New research suggests that neurons which track our movements are also involved in imaginary navigation

Brain cells involved in spatial navigation and mapping the environment also fire when we merely imagine moving through familiar surroundings, according to a new study by researchers at University College London. The research, published today in the journal Current Biology, shows that memory and imagination are intimately linked in the brain at the cellular level, and could help to explain some of the changes that occur in the early stages of Alzheimer’s Disease.

Related: The fly's neural compass works just like a mammal's

Related: 3D compass cells found in the bat brain

The discovery of an inhibitory memory circuit could lead to novel treatments for conditions such as PTSD

In order to remember, we must forget. Recent research shows that when your brain retrieves newly encoded information, it suppresses older related information so that it does not interfere with the process of recall. Now a team of European researchers has identified a neural pathway that induces forgetting by actively erasing memories. The findings could eventually lead to novel treatments for conditions such as post-traumatic stress disorder (PTSD).

We’ve known since the early 1950s that a brain structure called the hippocampus is critical for memory formation and retrieval, and subsequent work using modern techniques has revealed a great deal of information about the underlying cellular mechanisms. The hippocampus contains neural circuits that loop through three of its sub-regions – the dentate gyrus and the CA3 and CA1 areas – and it’s widely believed that memories form by the strengthening and weakening of synaptic connections within these circuits.

Related: Light switches memories on and off | Mo Costandi

Related: The Homer Simpson effect: forgetting to remember

“Badass” new method uses a magnetised protein to activate brain cells rapidly, reversibly, and non-invasively

Researchers in the United States have developed a new method for controlling the brain circuits associated with complex animal behaviours, using genetic engineering to create a magnetised protein that activates specific groups of nerve cells from a distance.

Understanding how the brain generates behaviour is one of the ultimate goals of neuroscience – and one of its most difficult questions. In recent years, researchers have developed a number of methods that enable them to remotely control specified groups of neurons and to probe the workings of neuronal circuits.

Related: Remote control of brain activity with heated nanoparticles

Related: Researchers read and write brain activity with light

State-of-the-art electron microscopy reveals the large-scale organization of the proteins that regulate neurotransmitter release

This spectacular image – which took the best part of a year to create – shows the fine structure of a nerve terminal at high resolution, revealing, for the very first time, an intricate network of fine filaments that controls the movements of synaptic vesicles.

The brain is soft and wet, with the consistency of a lump of jelly. Yet, it is the most complex and highly organized structure that we know of, containing hundreds of billions of neurons and glial cells, and something on the order of one quadrillion synaptic connections, all of which are arranged in a very specific manner.

Related: 3D model of a nerve terminal in atomic detail | Mo Costandi

Related: Blowing up the brain to reveal its finer details

Research suggests that gut bacteria may directly affect brain structure and function, offering new ways to treat multiple sclerosis and psychiatric conditions

Far from being silent partners that merely help to digest food, the bacteria in your gut may also be exerting subtle influences on your thoughts, moods, and behaviour. And according to a new study from researchers at University College Cork, your gut microbes might affect the structure and function of the brain in a more direct way, by regulating myelination, the process by which nerve fibres are insulated so that they can conduct impulses properly.

The surprising new findings, published today in the journal Translational Psychiatry, provide what is perhaps the strongest evidence yet that gut bacteria can have a direct physical effect on the brain, and suggest that it may one day be possible to treat debilitating demyelinating diseases such as multiple sclerosis, and even psychiatric disorders, by altering the composition of the gut’s microbial menagerie in some way or another.

Related: Brain’s immune cells hyperactive in schizophrenia

Related: White matter might matter much more than we thought | Mo Costandi

New research provides the first direct evidence that Zika virus causes severe birth defects, and explains exactly how it does so

“I lifted up my T-shirt to check on what I thought had just been a small heat rash,” writes BuzzFeed correspondent Ali Watkins. “It had shown up along the right of my back, extending out from a handful of mosquito bites I had picked up… it had seemed relatively tame [but] now, it was inching across the front of my stomach and down my legs... Meanwhile, my right eye was inflamed and bright red, almost akin to a busted blood vessel.”

Watkins is describing the symptoms of a Zika virus infection that she contracted on a recent trip to Mexico. For many people, infection with this mosquito-borne virus causes an illness with symptoms just like those experienced by Watkins: fever, skin rash, joint pain and conjunctivitis. For others, these symptoms are so mild that they go completely unnoticed.

Related: Zika virus spreads across Americas - in pictures

Related: Zika forest: birthplace of virus that has spread fear across the world

Mechanosensory hairs covering bumblebees’ bodies detect the small electrical fields emitted by flowers

Bumblebees use the fine hairs covering their bodies to detect electrical fields produced by the flowers they feed on and pollinate, according to a new study by researchers at the University of Bristol. The findings, just published in Proceedings of the National Academy of Sciences, may help to solve the mystery of how insects and other terrestrial creatures detect and respond to electric fields.

It’s well known that bumblebees use their sense of smell, as well as visual cues such as the colour, shape, and patterning of flowers, to find nectar, and in 2013, biologist Daniel Robert and his colleagues reported the surprising finding that they can also detect floral electric fields.

Related: Electric eels curl up to deliver double strength shocks

Related: Ancient arthropod brains surprise paleontologists

A toxin isolated from the Togo starburst tarantula provides new insights into pain mechanisms and could lead to new treatments for irritable bowel syndrome

With their large, hairy bodies and long legs, tarantulas are an arachnophobe’s worst nightmare. For pain researchers, however, these outsized spiders are a dream come true: Their venom contains a cocktail of toxins, each of which activates pain-sensing nerve fibres in different ways, and researchers in the United States have now identified one such toxin that will help them to better understand pain, and could also lead to treatments for the chronic pain associated with irritable bowel syndrome.

Physical pain signals are transmitted from the body to the brain by specialised sensory neurons called nociceptors. These pain-sensing neurons have cell bodies located just outside the spinal cord, and possess a single conductive fibre that splits in two, with one branch extending out towards the skin surface, and the shorter one entering the back of the cord.

Related: Uncomfortably numb: The people who feel no pain

Related: Researchers identify gatekeeper neurons that control pain and itch

New research reveals the secret behind the remarkable intelligence of some bird species

Related: Blind cave fish evolved a shrunken brain to save energy

Calling someone “bird brain” used to be considered as an insult. Birds’ brains are very small compared to those of mammals, and what’s more, they lack the heavily wrinkled cerebral cortex, which is characteristic of the human brain, and widely believed to the seat of intelligence. It was, therefore, widely assumed that birds aren’t very clever creatures, but recently this has started to change.

Related: Ravens cooperate with friends not foes

New research demonstrates an extreme form of inattentional blindness in which we fail to see the unexpected

There’s much more to visual perception than meets the eye. What we see is not merely a matter of patterns of light falling on the retina, but rather is heavily influenced by so-called ‘top-down’ brain mechanisms, which can alter the visual information, and other types of sensory information, that enters the brain before it even reaches our conscious awareness.

Related: Memory contaminates perception | Mo Costandi

Related: Language boosts invisible objects into visual awareness | Mo Costandi

New research shows that frigatebirds can sleep on the wing, with just one or both halves of their brain

When Charles Darwin arrived at the Galápagos Islands in 1839, he had the opportunity to observe the habits of frigatebirds, and marvelled at their graceful flight manoeuvres and their ability to soar up high. “When it sees any object on the surface of the water,” he wrote, “[it] descends from a great height… with the swiftness of an arrow; and at the instant of seizing with its long beak and outstretched neck, the floating morsel, it turns upwards, with extraordinary dexterity, by the aid of its forked tail, and its long, powerful wings.”

Related: Sleepy brains neglect half the world | Mo Costandi

Related: Birds pack more cells into their brains than mammals

A new imaging technique may give researchers fresh insights into brain development, function, and disease

The human brain is often said to be the most complex object in the known universe, and there’s good reason to believe that it is. That lump of jelly inside your head contains at least 80 billion nerve cells, or neurons, and even more of the non-neuronal cells called glia. Between them, they form hundreds of trillions of precise synaptic connections; but they all have moveable parts, and these connections can change. Neurons can extend and retract their delicate fibres; some types of glial cells can crawl through the brain; and neurons and glia routinely work together to create new connections and eliminate old ones.

These processes begin before we are born, and occur until we die, making the brain a highly dynamic organ that undergoes continuous change throughout life. At any given moment, many millions of them are being modified in one way or another, to reshape the brain’s circuitry in response to our daily experiences. Researchers at Yale University have now developed an imaging technique that enables them to visualise the density of synapses in the living human brain, and offers a promising new way of studying how the organ develops and functions, and also how it deteriorates in various neurological and psychiatric conditions.

Related: Brain’s immune cells hyperactive in schizophrenia

Related: 3D model of a nerve terminal in atomic detail | Mo Costandi

New research shows that the drug makes cells in the retina more sensitive to light

25 years ago, pharmacologist M. E. West of the University of the West Indies in Kingston, Jamaica, noted that local fisherman who smoke cannabis or drink rum made with the leaves and stems of the plant had “an uncanny ability to see in the dark,” which enabled them to navigate their boats through coral reefs. “It was impossible to believe that anyone could navigate a boat without compass and without light in such treacherous surroundings,” he wrote after accompanying the crew of a fishing boat one dark night, “[but] I was then convinced that the man who had taken the rum extract of cannabis had far better night vision than I had, and that a subjective effect was not responsible.”

Some of these crew members told West that Moroccan fishermen and mountain dwellers experience a similar improvement after smoking hashish, and in 2002, another research team travelled to the Rif mountains in Morocco to investigate further. They gave a synthetic cannabinoid to one volunteer, and hashish to three more, then used a newly developed piece of kit to measure the sensitivity of their night vision before and after. Confirming West’s earlier report, they found that cannabis improved night vision in all three of their test subjects.

Related: How marijuana impairs memory

Related: A brief history of psychedelic psychiatry | Mo Costandi

New research shows that a genetic mutation associated with schizophrenia alters the process of cellular differentiation, disturbing the balance of neurons and glia in the brain

Stem cells obtained from patients with schizophrenia carry a genetic mutation that alters the ratio of the different type of nerve cells they produce, according to a new study by researchers in Japan. The findings, published today in the journal Translational Psychiatry, suggest that abnormal neural differentiation may contribute to the disease, such that fewer neurons and more non-neuronal cells are generated during the earliest stages of brain development.

Schizophrenia is a debilitating mental illness that affects about 1 in 100 people. It is known to be highly heritable, but is genetically complex: so far, researchers have identified over 100 rare genetic variations and dozens of mutations associated with increased risk of developing the disease.

Related: Brain’s immune cells hyperactive in schizophrenia

Related: Turning urine into brain cells | Mo Costandi

It’s not just your waistline that suffers as you put on weight. Researchers are beginning to find puzzling new links between obesity, memory loss and dementia

Lucy Cheke and her colleagues at the University of Cambridge recently invited a few participants into her lab for a kind of ‘treasure hunt’.

The participants navigated a virtual environment on a computer screen, dropping off various objects along their way. They then answered a series of questions to test their memory of the task, such as where they had hidden a particular object.

Related: How your eyes betray your thoughts

Related: How to optimise your brain's waste disposal system

Related: Gut bacteria regulate nerve fibre insulation

Related: Obesity linked to memory deficits

New research shows that the rhythm of breathing directly impacts neural activity in a network of brain areas involved in smell, memory and emotions

The rhythm of breathing co-ordinates electrical activity across a network of brain regions associated with smell, memory, and emotions, and can enhance their functioning, according to a new study by researchers at Northwestern University. The findings, published in the Journal of Neuroscience, suggest that breathing does not merely supply oxygen to the brain and body, but may also organise the activity of populations of cells within multiple brain regions to help orchestrate complex behaviours.

Related: Your nose knows death is imminent | Mo Costandi

Related: A cooler way to evaluate brain surgery patients

New findings challenge our understanding of how the brain matures

Faces are important to us. From the moment we are are born, we prefer to look at faces than at other, inanimate objects, and, being social animals, we encounter faces every day of our lives. The face is the first thing we look to when identifying other people; faces also convey emotions, informing us of peoples’ mood, and from them we can usually determine a person’s sex and, sometimes, roughly how old they are. Eye movements can also reveal to us something about another person’s intentions.

Related: How your eyes betray your thoughts

Related: Live imaging of synapse density in the human brain

New research provides evidence for the idea that sleep restores cellular homeostasis in the brain and helps us to forget irrelevant information

We spend one third of our lives sleeping, but we still do not know exactly why we sleep. Recent research shows that that the brain does its housekeeping while we sleep, and clears away its waste. According to another hypothesis, sleep plays the vital role of restoring the right balance of brain synapses to enhance learning, and two studies published in today’s issue of Science now provide the most direct evidence yet for this idea.

We do know that sleep is important for consolidating newly formed memories. During waking hours, we learn all kinds of new information, both consciously and unconsciously. To store it, the brain modifies large numbers of synaptic connections, making some of them stronger and larger, and it’s now thought that as we sleep other synapses are weakened or destroyed, so that the important new information is stored for later use, while irrelevant material, which could interfere with learning, is not.

Related: The Homer Simpson effect: forgetting to remember

Related: How to optimise your brain's waste disposal system

New research shows that we can train our brains to become memory champions

To many of us, having to memorize a long list of items feels like a chore. But for others, it is more like a sport. Every year, hundreds of these ‘memory athletes’ compete with one another in the World Memory Championships, memorising hundreds of words, numbers, or other pieces of information within minutes. The current world champion is Alex Mullen, who beat his competitors by memorizing a string of more than 550 digits in under 5 minutes.

You may think that such prodigious mental feats are linked to having an unusual brain, or to being extraordinarily clever. But they are not. New research published in the journal Neuron shows that you, too, can be a super memorizer with just six weeks of intensive mnemonic training, and also reveals the long-lasting changes to brain structure and function that occur as a result of such training.

Related: The Homer Simpson effect: forgetting to remember

Related: A neural pathway that erases memories

Researchers at MIT have developed a new method of electrically stimulating deep brain tissues without opening the skull

Since 1997, more than 100,000 Parkinson’s Disease patients have been treated with deep brain stimulation (DBS), a surgical technique that involves the implantation of ultra-thin wire electrodes. The implanted device, sometimes referred to as a ‘brain pacemaker’, delivers electrical pulses to a structure called the subthalamic nucleus, located near the centre of the brain, and effectively alleviates many of the physical symptoms of the disease, such as tremor, muscle rigidity, and slowed movements.

DBS is generally safe but, like any surgical procedure, comes with some risks. First and foremost, it is highly invasive, requiring small holes to be drilled in the patient’s skull, through which the electrodes are inserted. Potential complications of this include infection, stroke, and bleeding on the brain. The electrodes, which are implanted for long periods of time, sometimes move out of place; they can also cause swelling at the implantation site; and the wire connecting them to the battery, typically placed under the skin of the chest, can erode, all of which require additional surgical procedures.

Related: Blowing up the brain to reveal its finer details

Related: Traces of memory in a dish | Mo Costandi

Belarus defies coronavirus concerns with VE Day parade, mayor of Milan issues warning, while football returns ... in the Faroe Islands

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As coronavirus infections approached 4 million worldwide, and Russia became a new hotspot for the outbreak, Belarus defied worries to hold a parade marking the 75th anniversary of victory over the Nazis, with thousands of people in attendance including elderly veterans.

South Korea, which is trying to relax physical distancing regulations, on Saturday shut down more than 2,100 clubs and bars in the capital after a new cluster of cases emerged, apparently linked to a single individual who had gone out while infected.

The Chinese president Xi Jinping has offered the North Korean leader, Kim Jong-un, support in tackling the coronavirus, state media said on Saturday.

As debates rage in other countries about the return of professional football, games will be played in the Faroe Islands on Saturday for the first time since the coronavirus outbreak.

Indonesia has reported its biggest daily increase in infections, with 533 new confirmed cases, taking the total to 13,645.

A French MP has failed in her bid to to get “love” added to the list of “compelling reasons” that must be given for anyone to travel more than 100km (62 miles) in the country.

Egypt’s president, Abdel-Fatah al-Sisi, approved amendments to the country’s state of emergency that granted him and security agencies additional powers, saying they were needed to combat the coronavirus outbreak.

Mexico’s president, Andrés Manuel López Obrador, said on Friday that he aimed to present plans next week to reopen the economy, as key sectors like car-making look to begin business again after over a month of quarantine measures.

Argentina will extend a quarantine covering its capital Buenos Aires but relax restrictions in the rest of the country.

Coronavirus crisis reveals weakness in supply chain as medicines in export ban rise from 29 to 196 this year

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NHS leaders and medical charities are calling for ministers to bring more drug manufacturing to the UK to reduce the risk of future shortages after the problems seen during the coronavirus crisis.

In addition to the well documented shortages of personal protective equipment, dealing with Covid-19 has placed huge strain on supplies of intensive care medicine, over-the-counter drugs and oxygen. The NHS has been forced to put new rationing measures in place to ensure hospitals do not run out.

The supply chain isn’t as good – isn’t as robust – as it could be

Over the past five years, Brighton-based photographer Richard Chivers has been shooting gas holders from London to Sunderland.for his project OFF-Grid, after learning that National Grid planned to demolish the structures. “They hold a certain nostalgia to our industrial heritage,” he says.

The myth of the American west meets the energy of riot grrrl in Justine Kurland’s photographs of free-spirited teenage girls

In 1997, Justine Kurland, then a fine arts student at Yale University, went in search of teenage girls to photograph. At a time of increasing conformity and commercialised ideas of beauty, the girls she had in mind were free-spirited and wild-haired; making dens and hanging out in woods, messing about in rivers, smoking in parking lots, lost in languid afternoons, careless not only of the male gaze but any onlookers at all.

Kurland started out on her quest in New Haven’s semi-industrial hinterland before travelling further afield over the next five years on a mazy road trip; if the girls were on the margins, then she would be too. She loosely choreographed the groups of teenagers that she found, but mostly invited the girls into a promising setting and let them do their thing. She took this photograph of four girls in an abandoned car in the millennium year, and called it Shipwrecked. The girls she chose invariably understood the idea of the pictures. “I can always spot people,” she has said. “It’s, like, really one of my superpowers. I can always tell which teenage girls would love living in the woods with their friends.”

When Rhys Graham first picked up his camera in lockdown, he assumed he would take a few portraits of friends. Now, weeks in, it has turned into a sprawling project documenting Australia’s new domesticity

In these strange, suspended times, a camera and lens can be an emotional bridge from one person to the next.

As a film-maker you become reliant on the manic energy of shooting and the warmth of your community – crews, actors, colleagues or subjects – to keep you buoyant.

After facing the existential threat of testing positive for Covid-19, these Australians describe the reactions of their communities

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When they emerged from isolation, one felt like an escapee, another saw friends turn on their heels and some questioned if they had really recovered. Though their symptoms varied, all the accounts from these people who have recovered from coronavirus echo the same sentiment: recovery came at a price. Weeks after getting better, strangers and loved ones still scrabble to create distance, afraid of contagion.

At the time of writing, 5,984 Australians had recovered from the 6,875 confirmed cases. While the emerging consensus is that recovery induces, at least, short-term immunity, the World Health Organization urges caution, and researchers and health authorities are racing to determine how long this defence lasts.

Jaston Khosa was one of 600,000 men from African countries who fought for Britain. He was quietly buried on VE Day after a life of abject poverty

In a crowded, Zambian slum on VE Day, a family gathered to bury one of the last veterans of Britain’s colonial army. Jaston Khosa of the Northern Rhodesia Regiment was laid to rest on the day the world commemorated the end of the war in which he fought.

The 95-year-old great-grandfather was among 600,000 Africans who fought for the British during World War Two, on battlefields across their own continent as well as Asia and the Middle East. Although their service has largely been forgotten, the mobilisation of this huge army from Britain’s colonies triggered the largest single movement of African men overseas since the slave trade.

Victor Grayson was briefly the most famous socialist in Edwardian England. But in 1920 he disappeared. His fate remains one of the most compelling mysteries in British political history

“Oh mad, foolish Grayson!”
Editorial in the socialist magazine The Clarion, August 1907

In the aftermath of the general election of February 1974, the mood in Marsden socialist club in west Yorkshire was grim. David Clark, the young Labour MP for Colne Valley, in which the former mill town of Marsden sits, had lost his seat. Clark gamely attempted to lift his activists’ spirits with a rousing speech. But one elderly stalwart remained unmoved: “Old Harry was sitting at the bar nursing a pint,” recalls Clark, who is now 80 and a Labour peer. “He said: ‘All due respect to master Dave, but we’ve only ever had one true socialist MP around here. And that was Victor Grayson.’”

Try a dark matt lipstick, but don’t be scary

Unless you are into goth, you wouldn’t look to The Addams Family for beauty inspiration. However, there’s a modern way to go there without alarming anyone on Zoom, and the fresh take at the Max Mara SS20 show makes the case. If you find the requisite black lips intimidating, replace with a less macabre deep burgundy or aubergine. Swap matt alabaster skin for something a little less lifeless – a decent tinted moisturiser will warm things up. Finish with a pastel wash of colour across the eyes. Immediately, everything looks less intense. Morticia would be mortified.

1. Jimmy Choo Seduction Lipstick in Purple Night £50, harrods.com
2. Huda Beauty Pastel Obsessions £27, selfridges.com
3. Laura Mercier Caviar Mascara £22, spacenk.com
4. Smashbox Always On Liquid Lips in Disorderly £19, smashbox.co.uk
5. Glossier Skywash Eyeshadow £15, glossier.com

Sales from online dealers has shot up during the lockdown. Here’s your chance to find some great deals and also to try some new bottles and grapes

Shaw and Smith Sauvignon Blanc, Adelaide Hills, Australia 2019 (£14.95, slurp.co.uk) With most of us living out most of our lives in the virtual world at the moment, it’s not surprising that a lot of wine buying has migrated online, too. Depending on which statistical data gatherer you believe, sales of alcohol online were up by as much as 50% in the first weeks of the crisis v “normal” times. A lot of those sales went through the virtual tills of the supermarkets, of course. But the online wine specialists have been benefiting, too. If you’re looking to dip a toe into online wine buying for the first time, many retailers are offering discounted mixed cases to get you started. Slurp.co.uk, for example, has a 10-bottle “Indulge in Isolation” case, which at £120 works out as a £50 discount. There are some nice wines in there, although, personally, I’d rather go à la carte on slurp’s extensive list, filling a case with bottles such as Shaw and Smith’s superbly zingy, pristine sauvignon.

De Martino Viejas Tinajas Cinsault, Itata, Chile 2018 (£14.95, virginwines.co.uk) One mixed case that I do like the look of is Virgin Wine’s selection of contemporary German bottles, which, includes pinot blanc and pinot noir as well as a scintillating example of the country’s most famous grape variety, Gunderloch Fritz’s Riesling, Rheinhessen 2017 (a bottle of which is £14.99 on its own; The Best of Modern Germany case of 12 bottles is £140). You could also include any of those Germans in a mixed case with a wine such as the gorgeously light, rosehippy-red fruited, clay amphora-made Viejas Tinajas from Chile. Meanwhile, the UK’s oldest wine retailer, and one of the first to make a success of online, Berry Bros & Rudd, has a tempting 12 for £200 mix and match offer of 30 smart bottles, which is pretty good value for wines from the likes of De Martino, the Loire’s Vincent Carême, Beaujolais’ Julien Sunier and the Douro’s Quinta de la Rosa.

A loving touch will get seedlings ready to plant

As spring turns to summer, gardeners everywhere will be itching to plant the seedlings and cuttings they’ve been raising indoors out in the garden. However, particularly for newbies, the effects of this transition from the cosseted conditions of a warm windowsill to the great outdoors can be a significant hurdle.

The reason why this switch is tricky is that plants have the amazing ability to adapt their anatomy to shield themselves from environmental threats, however they are only triggered to do so when stimulated by the threat itself. Indoors, plants enjoy stable temperatures, limited air movement and much lower light levels (as window glass filters out UVB rays). This means they tend to direct most of their energies into growing, instead of investing in these defences.

And they’re off! The baby peas and beans are out on their own. But will they survive?

Sleep restless, anxiety dreams, and if there wasn’t enough to be concerned about I am worrying about our baby beans and peas.

It is often like this in spring. The responsibility, it comes with the shorter nights and longer light, maybe I have more time on my hands. I have saved two hours a day on travelling and I only work a few miles’ walk from home. This extra time has now become a trip to the plot, or perhaps pottering on the terrace. A more intimate gardening relationship cemented in the spring mornings. Deepened, more dependent.

Author Dan Richards, who has travelled to the ‘ends of the earth’, says he is now applying similar coping skills to being alone and indoors for weeks

You join me overlooking an empty Edinburgh crossroads, an indoorsman considering my new neck of the woods. Near-empty buses roll down Dundas Street and shush across the junction in the haar (fog). In this brave moot world – a month of Christmas mornings so far – I watch lone joggers and mothers with children, and wave at good dogs. I write to my friends. I check in by phone. “Yes,” I say, several times a week, “Edinburgh’s very nice. Quiet.”

Two years ago, I spent several months travelling for a book, seeking out solitude and remote locations – strange to think now. I visited wild places on the edge – frozen Soviet ghost towns, Mars missions in the Utah desert, shrines perched high on Japanese mountains – as well as spartan structures whose wildness emanated from within, such as Simon Starling’s metamorphic installation Shedboatshed, the writing “Wendy houses” of Roald Dahl and Tove Jansson, and Roger Deakin’s Suffolk shepherd’s hut.

We may be spending less by not travelling to work, but with an uncertain future it’s time to take stock of personal finances

With gyms shut, taps turned off in pubs and the prospect of a holiday a distant dream, many people are finding their outgoings have dropped since lockdown. But the shadow of a looming recession and concern about whether jobs will even exist when offices reopen, means many are looking at their finances even more closely.

So what are the best ways to improve them amid extraordinary times and an uncertain future?

Dave Burd brings a lightly fictionalised tale of his comedy rap career in a new sitcom. Plus: The Fantastical Factory of Curious Craft. Here’s what to watch this evening

He gave McCartney tips on how to scream in tune and paved the way for everyone from Otis Redding to Prince. Richard Penniman showed the world how rock’n’roll could be a manifesto for personal liberation

Little Richard’s Rip It Up entered the UK top 30, right at the bottom, in December 1956. It looked up at a chart that included Bill Haley and Elvis Presley, but was mostly filled with light opera gloop such as Malcolm Vaughan’s St Therese of the Roses, three different versions of the cod-calypso of Cindy, Oh Cindy, and toddler-friendly novelties including Dickie Valentine’s Christmas Island and Mitchell Torok’s When Mexico Gave Up the Rhumba, while the spirit of the blitz lived on with Vera Lynn’s A House With Love in It. Play any of these records either side of Rip It Up and the effects are guaranteed goosebumps, an involuntary laugh and real surprise. With the sheer volume of Richard’s raw-throated scream – ebullient, gleeful, quite filthy – the shock of the new can still be felt. Rip It Up – that title alone!

Think of Bowie. Think of Prince. Little Richard was doing the same thing – with greater extravagance – decades earlier

The Observer’s critics recommend the best new arts shows to enjoy on TV, on the radio and online

Barber Shop Chronicles
A never-before-broadcast recording of Inua Ellams’s 2017 hit play splicing stories and banter with barbs and laughter. Available to stream for seven days from 7pm Thursday on the National Theatre’s YouTube channel. Clare Brennan

Author David McKee reveals why, 40 years on, his cautionary tale of the perils of ignoring children is still relevant

For the past 40 years it has been a warning to parents about the monstrous consequences of ignoring their children. Now new illustrations of the classic picture book Not Now, Bernard have been created to better reflect the daily life of families in the age of smartphones and tablets.

Eliza Hittman’s coming-of-age story about a US teenager seeking a termination is heartbreaking and painfully authentic

From Eliza Hittman, the remarkable writer-director of It Felt Like Love and Beach Rats, comes another drama that manages to blend the gritty authenticity of a documentary with the poetic sensibility of pure cinema. In her impressively measured and beautifully understated third feature, Hittman tells an oft-hidden story of reproductive rights – an age-old issue that has urgent contemporary relevance. Yet Never Rarely Sometimes Always never feels polemical. On the contrary, it is perhaps best described as a perfectly observed portrait of female friendship; a coming-of-age story with road-movie inflections, piercingly honest and deeply affecting.

Feature first-timer (and accomplished musician) Sidney Flanigan is superb as Autumn, a 17-year-old from Pennsylvania who discovers that she cannot get an abortion in her home town without parental consent. Quietly desperate, Autumn reluctantly confides in her more outgoing cousin Skylar (rising star Talia Ryder, soon to be seen in Spielberg’s West Side Story), who agrees to accompany her across state lines to New York. The pair imagine that the trip will be brief but find themselves spending days and nights on the streets, waiting for the procedure that Autumn was denied in Pennsylvania.

The former EastEnders actor talks about shooting a pilot on a deadly virus, telling British stories with a difference – and how playing a bit part as a pigeon changed his career

The so-called “curse of EastEnders” – the struggle for soap actors to transition into more prestigious dramatic roles after leaving the show – always weighed heavily on the mind of Himesh Patel.

So when he decided to leave the soap in 2016, after nine years playing Tamwar Masood, he knew whichever role he chose next would be critical in breaking typecast, perhaps even defining the rest of his career. He went to a friend whose theatre company, withWings, took inventive musical adaptations to the Edinburgh fringe. That year they were doing Le Bossu, a retelling of The Hunchback of Notre Dame. Patel mentioned that he wanted to get out of his comfort zone and do some theatre. “He came back to me and said, ‘Cool, well, I can offer you the role of a pigeon.’”

Prosecutor rejects Australia’s argument International Criminal Court has no jurisdiction because Palestine is ‘not a state’

The Australian government has told the International Criminal Court it should not investigate alleged war crimes in Palestine because Palestine is “not a state”, arguing the court prosecutor’s investigation into alleged attacks on civilians, torture, attacks on hospitals, and the use of human shields, should be halted on jurisdictional grounds.

Australia was lobbied to make the submission to the court by Israel, which is not a party to the court. But the office of the prosecutor has rejected Australia’s argument, saying it had not formally challenged Palestine’s right to be a party to the court before.

Rise of spy chief to premier comes as Iran struggles to maintain momentum months after killing of powerful general

In late February, six weeks after the Iranian general Qassem Suleimani was killed by a US drone, a candidate for Iraq’s vacant premiership was nervously preparing for an interview that would secure him the role.

Mustafa al-Kadhimi’s rise from intelligence chief to the seat of national power had been unorthodox, as was the journey he had just made – from Baghdad, where high-stakes appointments like his had mostly been made over the past decade.

Transport secretary announces £2bn package to get UK walking and cycling instead

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The enormity of the challenge of getting the UK back to work was laid bare on Saturday, as the government acknowledged that the capacity of Britain’s transport network will be reduced by 90%.

The transport minister, Grant Shapps, said at the daily Downing Street press briefing that even if a full public transport service is restored, the government’s two-metre physical distancing rule will mean 10% of the usual number of passengers will be able to travel.

At the go-getting estate agency’s AGM this week, all minds will be focused on getting out of a tricky situation

When a Foxtons employee looks in the mirror, the estate agent can discern a reflection that others cannot.

To them, the figure smiling back is a dashingly attired young tycoon – confident that their sharp wits are about to land them another tasty commission. But many of those attempting to buy a home in London might interpret that same image as – how shall we put this? – slightly less heroic.

Modest changes expected to include relaxing exercise rules and reopening garden centres

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Boris Johnson’s plans to ease the UK lockdown are likely to be in line with Wales, which would result in only modest changes such as the reopening of garden centres and libraries, and a relaxation of exercise rules, the Welsh first minister, Mark Drakeford, said on Saturday.

Drakeford said the prime minister’s announcement for England would be in line with the very smallest easing granted in Wales.

The museums of Europe have begun reopening their doors to art lovers desperate to see old favourites and new works

I am cursing my bad luck not to be stuck in lockdown in the Prado. A friend wishes she had stowed away in a closet before they bolted the doors of the National Gallery. Others would give anything for a week in the Rijksmuseum, a day in the Uffizi, an hour with Rembrandt or Vermeer, even just a few minutes with a Samuel Palmer moonscape in the Ashmolean or a Turner sunrise at Tate Britain. Museums are places of the heart.

We see art in time and place; we cannot see it otherwise. Of course there are other whereabouts of the works we most long to set eyes on again, during this evil pandemic: the cave paintings at Chaumet in France, Fra Angelico’s Annunciation in a Florentine monastery, Robert Smithson’s Spiral Jetty coiled in the glistening waters of the Great Salt Lake in Utah. These were all chosen in an unofficial and entirely self-selecting Twitter survey (mine), along with Leonardo’s The Last Supper and James Turrell’s Deer Shelter Skyspace, framing the blue heavens above Yorkshire Sculpture Park.

The highest rates of Covid-19 casualties are in countries run by know-nothing populists

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All of a sudden, and after years of bluffing, conservatives are warning of the dangers of jumping to hasty conclusions. Before I go any further, I must therefore say our newly scrupulous masters have a point. The league tables of national Covid-19 death figures are not the last word on the crisis, and may look different in a few weeks. That’s that done, then. Everybody happy? Good. Let’s get on with it.

In the world as it is, rather than as it may be, a shameful fact is undeniable. The highest Covid-19 casualties are in the US and the UK, where the mendacities of the populist right have deformed society. It turns out that being governed by Anglo-Saxon conservatives is a threat to the health of nations. Their rule kills the old and blights the futures of the young. To understand their ineptitude, think of how conservatism turned into a know-nothing culture in the past decade, and ask what Donald Trump and Boris Johnson would be doing in an alternative universe where they never came close to power.

Thatcher’s simplistic aversion to borrowing still haunts fiscal policy, but interest rates have been falling for many years

It is clear Boris Johnson has favoured his health advisers as he looks to ease the lockdown. Worries about a second coronavirus outbreak have clinched victory over concerns about keeping much of industry and commerce in a state of suspended animation.

After weeks of pleading by the Treasury to get the nation back to work, No 10 has opted to play it safe with people’s health, and particularly older people. And no wonder, after a hapless first few months in which the UK leapt to fourth place in probably the most ignominious league table in modern history – that of Covid-19 deaths per 100,000 population – behind Belgium, Spain and Italy.

The rights of the most vulnerable, including those with dementia, should not be violated

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Last week, driving to the shops, I passed a care home and saw a figure standing at an upstairs window: an old woman looking out at a world she could not enter. She looked like a prisoner. And in a way, that’s probably what she was.

Let’s talk about old people. Let’s talk about people in care homes, about people living with dementia and dying with dementia, out of sight and out of mind, and what the lockdown means for them. Let’s talk about what we are not talking about enough, not thinking about enough, not caring about enough.

Sincerity is an increasingly rare commodity among our leaders, but sombre addresses by the Queen and Germany’s president had it in spades

Public suspicion is often aroused by the neat use of rhetoric, or by hearing a clever trick of speech. It is understandable that a stylish phrase or a persuasive analogy from the mouth of an authority figure should be met with caution.

Many are now also wary of the comparisons with the Second World War that are lobbed at the population each week by politicians, for the globe is not waging a military campaign or fighting a battle, there is no violent human enemy to defeat. Instead, we are all engaged in a unique and sustained mass experiment in protection and survival.