science and technology

Amphipathic Emulsion Binder for Enhanced Performance of Lithium-Sulfur Batteries

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA01037J, Paper
Yuan He, Xulong Jing, Tianxing Lai, Dong Jiang, Chao Wan, Pavel S Postnikov, Olga Guselnikova, Lixin Xu, Xiaojun He, Yusuke Yamauchi , Biyu Jin
The application of polyvinylidene fluoride (PVDF) binder in lithium-sulfur batteries faces challenges due to inadequate adhesion, undesirable conductivities, limited lithium polysulfides absorbability, and its dependence on the use of toxic...
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science and technology

Green solvents in battery recycling: status and challenges

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D3TA07905H, Review Article
Wenyuan Qiao, Ren Zhang, Yikai Wen, Xinyi Wang, Zheng Wang, Guoqiang Tang, Minghao Liu, Hyokyeong Kang, Zafar Said, Jang-Yeon Hwang, Changhui Liu
A green solvent hybrid system will bring about sustainable development in the battery industry by efficiently and environmentally friendly recycling of valuable resources contained in waste batteries.
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science and technology

Molecular-polaron-coupling-enhanced photocatalytic CO2 reduction on copper phthalocyanine/NiMgFe layered double hydroxide nanocomposites

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D3TA07538A, Paper
Yuexian Li, Wenli Su, Xiaoyan Wang, Jun Lu, Wenkai Zhang, Shuo Wei
We built CuPcS/NiMgFe-LDHs composites and probed the unique photogenerated-carrier transfer mechanism. A series of long-range Forster energy transfers prolonged the lifetime of photogenerated carriers to match the timescale of surface reaction.
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science and technology

Constructing vacancy-rich metal phosphates by the spatial effect of ionic oligomers for enhanced OER activity

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA01706D, Paper
Yida Zhao, Xinyu He, Xiaoming Ma, Zhengxi Guo, Menghui Qi, Zhaoming Liu, Ruikang Tang
By rationally selecting ionic oligomers as building blocks, sub-nano-sized gaps can be constructed in the solid structure of catalysts. This can overcome the inherent limitations associated with vacancy formation of the traditional nucleation pathway.
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science and technology

Harvesting solar energy with a Ni-MOF-based evaporator for efficient solar thermal storage and steam generation

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA00203B, Paper
You Xu, Zhengyun Wang, Xianbao Wang, Zhenzhen Guo, Muhammad Sultan Irshad, Naila Arshad, Jiang Gong, Hongfang Liu, Guangfang Li
A hybrid solar evaporator comprising a Ni-based metal–organic framework material and a phase change material composite was fabricated for high performance solar-thermal energy storage and continuous solar vapor generation.
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science and technology

Fluorophore branching boosted photo-induced energy transfer in UiO-66 for ultrasensitive and instant hydrazine sensing

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA01549E, Paper
Ying Luo, Da Lei, Maohua Li, Yuansheng Ge, Jiguang Li, Baiyi Zu, Jun Yao, Xincun Dou
Metal organic frameworks (MOFs) have made great progress in the field of fluorescent sensing; however, whether the electronic structure and recognized sites can be adjusted by external functionalization still remains challenging.
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science and technology

S-doped TiN supported N, P, S-tridoped TiO2 with hetero-phase junctions for fuel cell startup/shutdown durability

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA01475H, Paper
Mitsuharu Chisaka, Jubair A. Shamim, Wei-Lun Hsu, Hirofumi Daiguji
A platinum group metal-free S-doped TiN-supported N, P, S-tridoped TiO2 catalyst with anatase/rutile TiO2 hetero-phase junctions is revealed to display a high durability against fuel cell startup/shutdown cycles not to lose its anion dopants.
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science and technology

Efficient first principles based modeling via machine learning: from simple representations to high entropy materials

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA00982G, Paper
Kangming Li, Kamal Choudhary, Brian DeCost, Michael Greenwood, Jason Hattrick-Simpers
Generalization performance of machine learning models: (upper panel) generalization from small ordered to large disordered structures (SQS); (lower panel) generalization from low-order to high-order systems.
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science and technology

Machine Learning Enabled Exploration of Multicomponent Metal Oxides for Catalyzing Oxygen Reduction in Alkaline Media

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA01884B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xue Jia, Hao Li
Low-cost metal oxides have emerged as promising candidates used as electrocatalysts for oxygen reduction reaction (ORR) due to their remarkable stability under oxidizing conditions, particularly in alkaline media. Recent studies...
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science and technology

Insight into piezoelectricity modulation mechanism of ZnO doped with Y ions

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA01317D, Paper
Zihan Wang, Yue Sun, Shenglong Wang, Da Xiong, Guo Tian, Longchao Huang, Boling Lan, Long Jin, Weiqing Yang, Weili Deng
ZnO is a performance-rich material due to its unique coupling of piezoelectricity and semiconductor properties. However, the intrinsic piezoelectric screening effect of ZnO weakens the electromechanical conversion efficiency and greatly...
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science and technology

The Role of Mn in Boosting Wide Potential Window on Solid Solution Derived Electrodes for Aqueous Supercapacitors

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA00979G, Paper
Ziying Shi, Enzuo Liu, Biao Chen, Junwei Sha, Lihua Qian, Zhijia Zhang, Xiaopeng Han, Wenbin Hu, Chunnian He, Naiqin Zhao, Jianli Kang
The interaction mechanism of the multi-element oxide electrodes remains a challenge, despite the fact that their synergy can not only improve the electronic structure, but also broaden the working potential...
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science and technology

Highly selective and high-performance sulfonated poly(ether ether ketone)-based hybrid membrane enabled by complexed UiO-66-NH2 and sulfonated graphitic carbon nitride for vanadium flow battery

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA00988F, Paper
Caiyuan Zhao, Haixia Wang, Lang Li, Liping Liu, Xinrui Cui, Haifeng Shi
A series of sulfonated poly(ether ether ketone) (SPEEK) hybrid membranes (SPEEK/NF) with a constant 1 wt% complexed nanofillers (NF) comprising of UiO-66-NH2 and sulfonated graphitic carbon nitride (s-g-C3N4) are prepared...
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science and technology

Enhanced surface reconstruction of V-Doped Ni3N driven by strong OH adsorption to boost 5-hydroxymethylfurfural electrooxidation for energy-saving H2 production

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA01543F, Paper
Qi Zhou, Juan Wang, Ga Jin, Huiling Liu, Cheng Wang
Coupling biomass electrooxidation with hydrogen evolution reaction (HER) provides an alternative approach for simultaneously increasing the energy efficiency of H2 production and producing high value-added chemicals. Here, a V-doped Ni3N...
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science and technology

Toward record high Zn2+ storage in carbon electrodes via pore confinement engineering

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA01191K, Paper
Xiubo Zhang, Chang Yu, Yuanyang Xie, Jinhe Yu, Yingbin Liu, Yi Yang, Jianjian Wang, Shuqin Lan, Siyi Hou, Kunlun Liu, Jieshan Qiu
The effective specific surface area is proposed and well correlated with Zn2+ storage, guiding maximum Zn2+ storage within carbon. Multiple in situ spectroscopy techniques clarify the co-adsorption mechanism of hydrated Zn2+, SO42−, and H+.
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science and technology

The fluorescence distinction of chiral enantiomers: a Zn coordination polymer sensor for the detection of cinchonine and cinchonidine

J. Mater. Chem. C, 2024, Advance Article
DOI: 10.1039/D4TC03506B, Paper
Wenping Hu, Nan Wu, Dechao Li, Yefang Yang, Shaowen Qie, Shuai Su, Ruijie Xu, Wenting Li, Ming Hu
A Zn coordination polymer was constructed to identify chiral cinchonine and cinchonidine with high sensitivity, selectivity, and reproducibility.
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science and technology

Plasticity tunable artificial synapses based on organic electrochemical transistors with aqueous electrolytes

J. Mater. Chem. C, 2024, Advance Article
DOI: 10.1039/D4TC03569K, Paper
Ruhua Wu, Miao Xie, Yuhua Cheng, Dan Zhao, Liang-Wen Feng, Jianhua Chen, Wei Huang
By regulating ion transporting kinetics and ion diffusion distances in organic mixed ionic–electronic conductor channels, highly tunable short- and long-term plasticity are obtained in vOECTs with aqueous electrolytes.
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science and technology

Pi-extended hypervalent iodine macrocycles and their supramolecular assembly with Buckminsterfullerene

J. Mater. Chem. C, 2024, Advance Article
DOI: 10.1039/D4TC04251D, Paper
Krishna Pandey, Samsul Arafin, Grayson Venus, Eli Jones, Yachu Du, Mina Dumre Pandey, Tahir Awais, Lichang Wang, Kyle N. Plunkett
Hypervalent iodine based macrocycles with enlarged aromatic cores can form extended supramolecular assemblies with Buckminsterfullerene.
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science and technology

Superconductivity above 30 K due to the introduction of oxygen element in CaFeAsF

J. Mater. Chem. C, 2024, Accepted Manuscript
DOI: 10.1039/D4TC03994G, Paper
Yixin Liu, Teng Wang, Zulei Xu, Da Jiang, Yi Zhao, Yanpeng Qi, Xiaoni Wang, Ming Yang, Mao Ye, Wei Peng, Gang Mu
Exploring new unconventional superconductors is of great value for both fundamental research and practical applications. It is a long-term challenge to develop and study more hole-doped superconductors in 1111 system...
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science and technology

Breaking the Trade-off Between ∆EST and Oscillator Strength in Hybrid LR/SR-CT Compounds for Enhanced TADF Performance

J. Mater. Chem. C, 2024, Accepted Manuscript
DOI: 10.1039/D4TC04549A, Paper
Nikhitha R., Anirban Mondal
Achieving an ideal thermally activated delayed fluorescence (TADF) emitter requires balancing a minimal singlet-triplet energy gap (∆EST) with a considerable oscillator strength (f), which are typically mutually exclusive. By strategically...
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science and technology

Multimodal anti-counterfeiting inks: modern use of an ancient pigment in synergy with a persistent phosphor

J. Mater. Chem. C, 2024, Accepted Manuscript
DOI: 10.1039/D4TC04228J, Paper
ALESSANDRO LO BIANCO, Francesco Armetta, Vitalii Boiko, Dariusz Hreniak, Maria Luisa Saladino
A multi-level luminescent, transparent and not-permanent inks for anti-counterfeiting systems and security was developed. The inks emit a radiation of different wavelength depending on the radiation used to illuminate them,...
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science and technology

Stronger Polar Ferromagnetism and Narrower Optical Band Gaps in Two-Dimensional Hybrid Copper Perovskites Induced by Bromine-Substitution

J. Mater. Chem. C, 2024, Accepted Manuscript
DOI: 10.1039/D4TC03532A, Paper
Ceng Han, Jason Allan McNulty, Alasdair Bradford, Alexandra Slawin, Stephen Lee, Philip Lightfoot
Two-dimensional (2D) organic–inorganic hybrid perovskites are attracting great interest due to their structural tunability and rich functional characteristics. Here, we report a series 2D layered hybrid copper (II) halide perovskites...
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science and technology

Dopant-free Tert-butyl Zn (II) Phthalocyanines: Impact of Substitution on Photo-Physical Properties in Their Role in Perovskite Solar Cells

J. Mater. Chem. C, 2024, Accepted Manuscript
DOI: 10.1039/D4TC04013A, Paper
Mahdi Gassara, Jose Garcés-Garcés, Luis Lezama, Javier Ortiz, Fernando Fernandez-Lazaro, Samrana Kazim, Angela Sastre-Santos, Shahzada Ahmad
We synthesized molecular hole-transporting materials (HTMs) featuring a zinc phthalocyanine (ZnPc) central core and modulated the non-perypheral position with different numbers of tert-butyl groups. The synthesized molecules were also integrated...
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science and technology

Giant Magnetocaloric Effect in Fe doped Rare earth Orthochromite GdCr0.5Fe0.5O3

J. Mater. Chem. C, 2024, Accepted Manuscript
DOI: 10.1039/D4TC03873H, Paper
Abinash Prusty, Sudipta Mahana, B. Sheetal Priyadarshini, Andrei Gloskovskii, Dinesh Topwal, Unnikrishnan Manju
In this manuscript we present the magnetic and magnetocaloric property investigations of Fe doped orthochromite system GdCr0.5Fe0.5O3, along with the structural, electronic and thermal properties. Manifestations of orbital mediated electron-phonon...
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science and technology

Chemical synthetic approaches to mimic the TRAIL: promising cancer therapeutics

RSC Med. Chem., 2024, 15,3639-3651
DOI: 10.1039/D4MD00183D, Review Article
Abdullah-Al Masum, Shin Aoki, Md. Mahbubur Rahman, Yosuke Hisamatsu
TRAIL induced apoptosis signalling by death receptors (DR4/DR5).
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science and technology

In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP

RSC Med. Chem., 2024, 15,3674-3694
DOI: 10.1039/D4MD00580E, Research Article
Jinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin Jin
Oridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.
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science and technology

New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation

RSC Med. Chem., 2024, 15,3759-3777
DOI: 10.1039/D4MD00498A, Research Article
Lucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. Enriz
A diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.
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science and technology

Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation

RSC Med. Chem., 2024, 15,3778-3794
DOI: 10.1039/D4MD00281D, Research Article
Carolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. Pilli
A novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.
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science and technology

Preventing SARS-CoV-2 infection using Fv-antibodies targeting the proprotein convertase (PPC) cleavage site

RSC Med. Chem., 2024, 15,3704-3710
DOI: 10.1039/D4MD00552J, Research Article
Jaeyong Jung, Jeong Soo Sung, Soonil Kwon, Hyung Eun Bae, Min-Jung Kang, Joachim Jose, Misu Lee, Jae-Chul Pyun
Fv-antibodies targeting the PPC region of SARS-CoV-2 to prevent infection, screened from an Fv-antibody library (displayed on outer membrane of E. coli cell).
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science and technology

Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity

RSC Med. Chem., 2024, 15,3711-3727
DOI: 10.1039/D4MD00584H, Research Article
Sara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-Dias
A series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.
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science and technology

Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction

RSC Med. Chem., 2024, 15,3652-3673
DOI: 10.1039/D4MD00425F, Review Article
Semim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra Borah
Metabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.
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science and technology

A photoswitchable CENP-E inhibitor with single blue-green light to control chromosome positioning in mitotic cells

RSC Med. Chem., 2024, 15,3795-3799
DOI: 10.1039/D4MD00458B, Research Article
Kazuya Matsuo, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki
A photoswitchable centromere-associated protein E (CENP-E) inhibitor based on the 4-methylaminoazobenzene photoswitch is reported, which is characterized with cistrans photoisomerization with blue-green light and fast thermal relaxation.
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science and technology

Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells

RSC Med. Chem., 2024, 15,3728-3745
DOI: 10.1039/D4MD00476K, Research Article
Vincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien Fortin
New water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.
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science and technology

Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety

RSC Med. Chem., 2024, 15,3837-3852
DOI: 10.1039/D4MD00426D, Research Article
Abdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L. K. Wong, Van T. D. Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M. C. Chow, Patrick J. Bednarski
Structure-guided optimization of fexinidazole led to analog (S)-51, a promising lead compound with superior activity, improved metabolic stability, and enhanced hERG safety
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science and technology

Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators

RSC Med. Chem., 2024, 15,3800-3816
DOI: 10.1039/D4MD00585F, Research Article
Marwa Abdel-Motaal, Dalal Ali Aldakhili, Ayman B. Farag, Ayman Abo Elmaaty, Marwa Sharaky, Nadia A. Mohamed, Saad Shaaban, Abdullah Yahya Abdullah Alzahrani, Ahmed A. Al-Karmalawy
Novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.
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science and technology

Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation

RSC Med. Chem., 2024, 15,3880-3888
DOI: 10.1039/D4MD00414K, Research Article
Phuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. Vo
Novel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.
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science and technology

Prediction of synergistic gemcitabine-based combination treatment through a novel tumor stemness biomarker NANOG in pancreatic cancer

RSC Med. Chem., 2024, 15,3853-3861
DOI: 10.1039/D4MD00165F, Research Article
Jiongjia Cheng, Ting Zhu, Shaoxian Liu, Jiayu Zhou, Xiaofeng Wang, Guangxiang Liu
The synergistic effect observed in gemcitabine-based combination therapies targeting pancreatic cancer stem cells was correlated with the inhibiting effect on the expression of stemness-related gene NANOG.
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science and technology

Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling

RSC Med. Chem., 2024, 15,3746-3758
DOI: 10.1039/D4MD00122B, Research Article
Open Access
Shadid U. Zaman, Piyusha P. Pagare, Hongguang Ma, Rosalie G. Hoyle, Yan Zhang, Jiong Li
We designed and synthesized novel IOX1-based PROTACs, which can selectively degrade KDM3A and KDM3B to eliminate colorectal cancer stem cells through inhibition of Wnt signaling.
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science and technology

Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway

RSC Med. Chem., 2024, 15,3817-3836
DOI: 10.1039/D4MD00477A, Research Article
Maha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa Matboli
ZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.
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science and technology

Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors

RSC Med. Chem., 2024, 15,3862-3879
DOI: 10.1039/D4MD00313F, Research Article
Daniele Pala, David Clark, Christine Edwards, Elisa Pasqua, Laura Tigli, Barbara Pioselli, Piotr Malysa, Fabrizio Facchinetti, Fabio Rancati, Alessandro Accetta
This study reports a novel, potent and selective series of ROCK inhibitors based on 8-(azaindolyl)-benzoazepinones identified through a core-hopping strategy.
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science and technology

Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery

RSC Med. Chem., 2024, 15,3695-3703
DOI: 10.1039/D4MD00546E, Research Article
Miyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke Demizu
A novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.
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science and technology

Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy

RSC Med. Chem., 2024, 15,3912-3912
DOI: 10.1039/D4MD90040E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex Joseph
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science and technology

Anticancer potential of copper(I) complexes based on isopropyl ester derivatives of bis(pyrazol-1-yl)acetate ligands

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00610K, Research Article
Open Access
Maura Pellei, Carlo Santini, Miriam Caviglia, Jo' Del Gobbo, Chiara Battocchio, Carlo Meneghini, Simone Amatori, Chiara Donati, Eleonora Zampieri, Valentina Gandin, Cristina Marzano
In this paper, the isopropyl ester derivatives LOiPr and L2OiPr of bis(pyrazol-1-yl)acetic acid and bis(3,5-dimethyl-pyrazol-1-yl)acetic acid were used as chelators for the preparation of the new Cu(I) phosphane complexes 1-4....
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science and technology

Advances in Detecting Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using Molecular Receptors and Nanostructured Assemblies

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00661E, Review Article
Avijit Kumar Das
The detection and quantification of non-steroidal anti-inflammatory drugs (NSAIDs) are crucial due to their widespread use and potential impact on human health and the environment. This review provides a comprehensive...
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science and technology

Affordable generics will stay relevant amid a premiumisation trend: Bhushan Akshikar

GSK will keep its existing portfolios while entering areas like oncology, said company officials at its centenary celebrations




science and technology

Afghanistan attends U.N. climate talks for first time since Taliban return to power

Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan




science and technology

Doctor stabbed at Kalaignar Centenary Super Speciality Hospital in Chennai; one arrested

The oncologist who was attacked has been identified as Balaji Jagannath. He has been admitted in the ICU, and his condition is said to be critical




science and technology

Why are countries fighting over climate finance at COP29?

Here is what you need to know about the November 11-22 summit talks on finance.




science and technology

COP29: India, other developing countries demand fair climate finance commitments

India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments




science and technology

Millions of Nigerians go hungry as floods compound hardship

Torrential rains and floods in 29 of Nigeria's 36 states this year have destroyed more than 1.5 million hectares of cropland, affecting more than nine million people




science and technology

29th Climate Conference (COP) tracker | Day 2 LIVE: Key speeches, UK NDC, and India’s reaction at 5 p.m. on November 13

Vibhuti Garg, an Associate and Senior Energy Specialist with over 13 years of experience in the energy sector, will guide us through the implications of these financial negotiations and the potential impacts on global energy transitions and climate commitments at 5 p.m. on November 13