Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI01942C, Research Article

Zhou Fang, Yi Tong, Yue Yang, Anjun Hu, Jianping Long, Yan Zhao, Xin Lai, Daojiang Gao, Mengjiao Liu
The present work simultaneously addresses the structural instability and poor diffusion kinetics of NH₄V₄O₁₀ cathodes using Ag⁺ intercalation, providing a new perspective on transition metal ion intercalation towards high-performance cathodes for AZIBs.
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Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02135E, Research Article

Tao Shao, Xianmeng Song, Zongnan Wei, Shuaibing Yang, Siying Zhang, Rong Cao, Minna Cao
Pd NP modification with Me₁₀CB[5]–M capsules boosted CO₂RR by enhancing CO₂ adsorption, tuning Pd's electronic structure, and optimizing *COOH/*CO binding.
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Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02280G, Research Article

Qixian Ren, Wangfei Che, Mengmeng Chen, Chen Cui, Yabo Wu, Zhi Su
Thioantimonates containing high oxidation state Sb5+ have proven to exhibit excellent performance in the design of new materials such as infrared optics crystals and lithium-ion batteries. However, as described by...
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Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02451F, Review Article

Chunwen Sun
The progress of nanoengineering of electrodes fabricated by various methods for SOFCs operating at low and intermediate temperatures is reviewed. Future research directions on nanoengineering of cathodes for next-generation SOFCs are also provided.
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Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02262A, Research Article

Tamara A. Bazhenova, Vyacheslav Kopotkov, Denis V. Korchagin, Elena Yureva, Michael V. Zhidkov, Alexey I Dmitriev, Ilya Yakushev, N. N. Efimov, Konstantin Andreevich Babeshkin, Vladimir Sergeevich Mironov, Eduard B. Yagubskii
A series of three new seven-coordinate pentagonal-bipyramidal (PBPY-7) Dy(III) complexes [Dy(L^CH3)(Cy₃PO)₂]ClO₄∙CH₃CN (1), [Dy(L^2(t-Bu))(Ph₃PO)₂]ClO₄∙0.63C₂H₅OH (2), [Dy(L^OCH3)(Ph₃PO)₂]ClO₄∙2H₂O (3) including various chelating pentadentate ligands with a [N₃O₂]²⁻ binding node in the equatorial plane,...
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Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02296C, Research Article

Katarzyna Zakret-Drozdowska, Bożena Szermer-Olearnik, Waldemar Goldeman, Michalina Gos, Dawid Drozdowski, Anna Gągor, Tomasz M. Goszczyński
Over the past decade, considerable scientific attention has been given to adapting cobalt bis(dicarbollides) as innovative agents with various biomedical applications. Although the studied compounds show great potential in this...
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Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02449D, Review Article

Ping Zhang, Yongchong Yu, Reyila Tuerhong, Xinyu Du, Keyi Chai, Xiaoping Su, Qiong Su, Shujuan Meng, Lijuan Han
The conventional synthetic ammonia industry is characterized by its high energy consumption, necessitating the exploration of a new environmentally sustainable method for NH3 synthesis. A prospective alternative to the Haber-Bosch...
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Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02422B, Research Article

Gengxin Wu, Yong-Kang Zhu, Dongxia Li, Jia-Rui Wu, Yan Wang, Zhiquan Zhang, Ying-Wei Yang
Engineering ideal functional coordination polymers (CPs) via post-synthetic modification has emerged as a powerful synthetic strategy to achieve desirable functionalities and superior properties. In this work, we report a versatile...
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Lab Chip, 2024, 24,2005-2016
DOI: 10.1039/D3LC00578J, Paper

Hossein Dayyani, Alireza Mohseni, Mohamad Ali Bijarchi
The manipulation of biocompatible magnetic liquid marbles, formed by wrapping magnetic nanoparticles around water droplets, on the water surface under the steady and variable magnetic fields.
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Lab Chip, 2024, 24,1965-1976
DOI: 10.1039/D3LC01007D, Paper

Wei-Jen Soong, Chih-Hung Wang, Chihchen Chen, Gwo-Bin Lee
We devised an innovative method for automated sorting of extracellular vesicles (EVs) employing optically-induced dielectrophoresis on an integrated microfluidic chip. EVs of three distinct size categories could be isolated in 1 h at a purity of 86%.
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Lab Chip, 2024, 24,2049-2057
DOI: 10.1039/D3LC00707C, Paper

Open Access

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Fumiaki Yokoyama, André Kling, Petra S. Dittrich
A microdevice with narrow winding channels is introduced to trap and culture single bacterial cells. It is used to study growth patterns of the cells and to monitor secretion of extracellular vesicles under treatment with an antibiotic drug.
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Lab Chip, 2024, 24,2017-2024
DOI: 10.1039/D3LC01050C, Paper

Samantha Bourg, Karol Rakotozandriny, Ivan T. Lucas, Emmanuel Letavernier, Christian Bonhomme, Florence Babonneau, Ali Abou-Hassan
The successful formation of a carbonated apatite coating inside a micrometer channel is described, which was used to investigate its role on the formation of calcium oxalate crystals in the context of kidney stones.
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Lab Chip, 2024, 24,1930-1946
DOI: 10.1039/D3LC00859B, Paper

Open Access

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Felix Richter, Maryline Calonne-Salmon, Marcel G. A. van der Heijden, Stéphane Declerck, Claire E. Stanley
A new microfluidic platform – the AMF-SporeChip – enables immobilisation of arbuscular mycorrhizal fungal spores and confrontation of asymbiotic hyphae with physical obstacles, allowing the identification of various exploration strategies.
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Lab Chip, 2024, 24,1977-1986
DOI: 10.1039/D3LC01017A, Paper

Liyu Dai, Xiaomin Wu, Huimin Hou, Zhifeng Hu, Yukai Lin, Zhiping Yuan
Cuboid pump systems driven by liquid metal multi-droplets using pillars to restrain the motion of droplets are designed, which achieve a significant increase in the flow rate of the pump.
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Lab Chip, 2024, 24,1903-1917
DOI: 10.1039/D3LC00908D, Paper

Zhangjie Li, Kai Niu, Chenyang Zhou, Feifan Wang, Kangyi Lu, Yijun Liu, Lian Xuan, Xiaolin Wang
We developed a multifunctional cardiac microphysiological system on transparent electrodes, enabling simultaneous electrical signal monitoring and optical observations of cardiac tissue, holding promise for applications in cardiac drug development.
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Lab Chip, 2024, 24,1887-1902
DOI: 10.1039/D3LC00507K, Paper

Open Access

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Chu-Chun Liang, Po-Yen Chen, Nien-Che Liu, I-Chi Lee
A 3D neural spheroid-based system with an interstitial level of flow for simulating the brain microenvironment toward a dynamic amyloid-β induced neuronal toxic model was established. A real-time impedance recording was used to monitor the neural network formation and disconnection.
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Lab Chip, 2024, 24,2107-2121
DOI: 10.1039/D3LC01075A, Paper

Open Access

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Wannes Verbist, Jolien Breukers, Sapna Sharma, Iene Rutten, Hans Gerstmans, Lotte Coelmont, Francesco Dal Dosso, Kai Dallmeier, Jeroen Lammertyn
A novel platform, called SeParate, enabling accurate multiplex droplet sorting by integrating serial and parallel sorting principles for three model systems with increasing complexity and intra-subpopulation variation in fluorescence intensities.
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Lab Chip, 2024, 24,2039-2048
DOI: 10.1039/D4LC00073K, Paper

Open Access

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Georgeta Vulpe, Guoyi Liu, Sam Oakley, Guanghao Yang, Arjun Ajith Mohan, Mark Waldron, Sanjiv Sharma
Development of wearable sensing devices for minimally invasive and real time monitoring of physiological information in ambulatory conditions.
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Lab Chip, 2024, 24,2025-2038
DOI: 10.1039/D3LC01044A, Paper

Qiyue Luan, Ines Pulido, Angelique Isagirre, Julian Carretero, Jian Zhou, Takeshi Shimamura, Ian Papautsky
Agarose microwell platform for modeling lung carcinoma using patient-derived tissues to decipher cancer associated fibroblast-induced drug resistance.
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Lab Chip, 2024, 24,2069-2079
DOI: 10.1039/D3LC00830D, Paper

Open Access

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Chaeeun Lee, Sumit Kumar, Juhee Park, Yongjun Choi, Elizabeth Maria Clarissa, Yoon-Kyoung Cho
Tonicity-induced cargo loading into extracellular vesicles (EVs) is achieved through controlled membrane permeability, ensuring cargo incorporation without causing damage to the EV membrane.
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Lab Chip, 2024, 24,1947-1956
DOI: 10.1039/D3LC00656E, Paper

Open Access

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Klaudia Staskiewicz, Maria Dabrowska-Zawada, Lukasz Kozon, Zofia Olszewska, Lukasz Drewniak, Tomasz S. Kaminski
Novel microfluidic technique for functional selection of biosurfactant-producing microorganisms. Single bacterial cells are encapsulated into picoliter droplets for clonal cultivation and passively sorted at high throughput by interfacial tension.
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Lab Chip, 2024, 24,1867-1874
DOI: 10.1039/D3LC00796K, Perspective

Open Access

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Umut A. Gurkan, David K. Wood, Dorn Carranza, Luke H. Herbertson, Scott L. Diamond, E. Du, Suvajyoti Guha, Jorge Di Paola, Patrick C. Hines, Ian Papautsky, Sergey S. Shevkoplyas, Nathan J. Sniadecki, Vamsee K. Pamula, Prithu Sundd, Asif Rizwan, Pankaj Qasba, Wilbur A. Lam
In this perspective article, we present the state of the microfluidic field regarding current limitations and propose future directions and new approaches for the field to advance lab-on-a-chip technologies closer to translation and clinical use.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00006D, Paper

Seyedaydin Jalali, Ponnambalam Ravi Selvaganapathy
A scalable method for creating perfusable 3D tissue constructs using self-assembly is introduced. Unlike conventional cell injection methods, here we leverage cell migration to form tissue barriers of low permeability, mimicking in vivo environments.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC00743J, Tutorial Review

Open Access

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Olivia M. Young, Xin Xu, Sunandita Sarker, Ryan D. Sochol
This Tutorial Review highlights strategies for leveraging the micron-to-submicron-scale additive manufacturing technique, “direct laser writing”, to enable 3D microfluidic technologies.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC00891F, Paper

Yu-Hsiang Hsu, Wen-Chih Yang, Yi-Ting Chen, Che-Yu Lin, Chiou-Fong Yang, Wei-Wen Liu, Subhashree Shivani, Pai-Chi Li
The DC-MPS device uses a velocity V-clamp to create a partition with a steep concentration gradient for simultaneously developing vasculogenic vessels and a tumor. It enables vessel–tumor interaction to develop a tumor model with angiogenic vessels.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC00933E, Paper

Open Access

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Huynh Quoc Nguyen, Van Dan Nguyen, Vu Minh Phan, Tae Seok Seo
The COVID-19 pandemic greatly impacted the in vitro diagnostic market, leading to the development of new technologies such as point-of-care testing (POCT), multiplex testing, and digital health platforms.
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Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00118D, Paper

Open Access

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Jiaheng Li, Lok Ting CHU, Hogi Hartanto, Guihuan Guo, Lu LIU, Jianpeng WU, Minghui Wu, Chenyu Cui, Gaobo Wang, Wengang LIU, Hoi Kwan Kwong, Siying WU, Ting-Hsuan Chen
Mucosal antibodies at the upper respiratory tract are the earliest and most critical responders to prevent respiratory infections, providing an indication to rapidly evaluate immune protection. Here, we report a...
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00131A, Paper

Fahima Akther, Hedieh Fallahi, Jun Zhang, Nam-Trung Nguyen, Hang Thu Ta
An atherothrombosis-on-chip model to evaluate thrombosis risk and patient-specific treatment strategy.
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Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D3LC01062G, Paper

Open Access

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Steven A. Soper, Chathurika Rathnayaka, Indu Chandrasoma, Junseo Choi, Katie Childers, Maximillian Chibuike, Khurshed Akabirov, Farhad Shiri, Adam R Hall, Collin J McKinney, Matthew David Verber, Sunggook Park
We report the generation of ~8 nm dual in-plane pores fabricated in a thermoplastic via nanoimprint lithography (NIL). These pores were connected in series with nanochannels, one of which served...
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC01101A, Paper

Wei Wang, Jaime de la Fuente Diez, Nicolas Delsuc, Juan Peng, Riccardo Spezia, Rodolphe Vuilleumier, Yong Chen
A new method uses piezoelectric and microfluidic tuning to study vibrational polaritons in liquids under flow. This enables modifying cavity length adjustments and flexibility in experimental setups.
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Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D3LC01066J, Paper

Open Access

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Artur Davletshin, Wen Song
Fluid-solid interactions in nanoporous materials underlie processes fundamental to nature and the engineered environment, including the thermochemical transformation of argillaceous materials during high-level nuclear waste disposal. Operando fluid-solid resolution at...
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Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D3LC00854A, Paper

Lu Xin, Xi Xiao, Wen Xiao, Ran Peng, Hao Wang, Feng Pan
The incidence of urothelial carcinoma continue to rise annually, particularly among the elderly. Prompt diagnosis and treatment can significantly enhance patient survival and quality of life. Urine cytology remains a...
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00165F, Paper

Xiaoming Chen, Shun Liu, Mo Shen, Jishun Shi, Chungang Wu, Zhipeng Song, Yong Zhao
We develop a microfluidic device with closed right-angle bipolar electrodes to realize dielectrophoretic characterization and selection of non-spherical flagellate algae.
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Lab Chip, 2024, 24,2176-2192
DOI: 10.1039/D3LC00912B, Paper

Open Access

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Priscilla Delgado, C. Alessandra Luna, Anjana Dissanayaka, Oluwamayokun Oshinowo, Jesse J. Waggoner, Sara Schley, Todd Fernandez, David R. Myers
This activity enables students to construct geometrically complex microfluidics at their desk with no specialized equipment. It can be easily transported, and helped students significantly improve their understanding of miniaturization science.
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Lab Chip, 2024, 24,2224-2236
DOI: 10.1039/D3LC00714F, Paper

Open Access

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Simon Seidel, Katja F. Winkler, Anke Kurreck, Mariano Nicolas Cruz-Bournazou, Katharina Paulick, Sebastian Groß, Peter Neubauer
This publication introduces a thermal segment microwell plate control device, integrating smart sensor technology and standardized well-plate geometry for automated biolab setups. It is tested in a high-throughput enzymatic activity assay.
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Lab Chip, 2024, 24,2237-2252
DOI: 10.1039/D3LC00694H, Paper

Open Access

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Nilay Vora, Prashant Shekar, Taras Hanulia, Michael Esmail, Abani Patra, Irene Georgakoudi
We present a deep-learning enabled, label-free flow cytometry platform for identifying circulating tumor cell clusters in whole blood based on the endogenous scattering detected at three wavelengths. The method has potential for in vivo translation.
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Lab Chip, 2024, 24,2262-2271
DOI: 10.1039/D4LC00055B, Paper

Kawin Khachornsakkul, Ruben Del-Rio-Ruiz, Lita Chheang, Wenxin Zeng, Sameer Sonkusale
A carbon dots and dopamine-imprinted polymer was immobilized onto a distance-based paper channel for simultaneous detection of three cytokine biomarkers without requiring expensive reagents and instruments.
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Lab Chip, 2024, 24,2317-2326
DOI: 10.1039/D4LC00151F, Paper

Open Access

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Amirreza Gholivand, Olivera Korculanin, Knut Dahlhoff, Mehrnaz Babaki, Timo Dickscheid, Minne Paul Lettinga
Taking microfluidics to the third dimension causes scrambling of memory effects in blood flow due to out-of-plane vessel structures.
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Lab Chip, 2024, 24,2358-2359
DOI: 10.1039/D4LC90026J, Correction

Open Access

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Lei Mou, Kalpana Mandal, Marvin Magan Mecwan, Ana Lopez Hernandez, Surjendu Maity, Saurabh Sharma, Rondinelli Donizetti Herculano, Satoru Kawakita, Vadim Jucaud, Mehmet Remzi Dokmeci, Ali Khademhosseini
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Lab Chip, 2024, 24,2287-2297
DOI: 10.1039/D3LC00866E, Paper

Arata Tsuchida, Taikopaul Kaneko, Kaori Nishikawa, Mayu Kawasaki, Ryuji Yokokawa, Hirofumi Shintaku
We introduce a simple integrated analysis method that links cellular phenotypic behaviour with single-cell RNA sequencing by utilizing a combination of optical indices from cells and hydrogel beads.
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Lab Chip, 2024, 24,2327-2334
DOI: 10.1039/D4LC00176A, Paper

Open Access

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Aravind M, Sajan D. George
Adhesive contrast contact lens fabricated by selective lubricant grafting splits tear film on specified zone by secretion and blinking. Integrating the contact lens with the spectroscopic technique offers an efficient platform for biomolecule sensing.
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Lab Chip, 2024, 24,2298-2305
DOI: 10.1039/D3LC00730H, Paper

Mahdi Samadi Khezri, Mohammad Reza Housaindokht, Mojtaba Firouzi
A volumetric bar-chart chip (V-chip) is a microfluidic device based on distance-based quantitative measurement that visualizes analyte concentration without the need for apparatus or data processing.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC00931A, Perspective

Open Access

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Fu Der Chen, Ankita Sharma, David A. Roszko, Tianyuan Xue, Xin Mu, Xianshu Luo, Hongyao Chua, Patrick Guo-Qiang Lo, Wesley D. Sacher, Joyce K. S. Poon
We explore the development of multifunctional nanophotonic neural probes, integrating microelectrodes, optical emitters, and microfluidic channels for multimodal brain mapping.
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Lab Chip, 2024, 24,2306-2316
DOI: 10.1039/D3LC01045G, Paper

Sabah H. Al-Jaf, Sameera Sh. Mohammed Ameen, Khalid M. Omer
On-site monitoring of ions in drinking water is essential for safeguarding public health, ensuring high water quality, and preserving the ecological balance of aquatic ecosystems.
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Lab Chip, 2024, 24,2335-2346
DOI: 10.1039/D4LC00032C, Paper

Rodin Chermat, Elena Refet-Mollof, Yuji Kamio, Jean-François Carrier, Philip Wong, Thomas Gervais
We introduce the first brachytherapy-on-chip device for in vitro testing of brachytherapy on naturally hypoxic tumor spheroids, for translational research and drug development.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00087K, Paper

Mohammad Mahdi Mardanpour, Ayyappasamy Sudalaiyadum Perumal, Zahra Mahmoodi, Karine Baassiri, Gala Montiel-Rubies, Kenneth M. LeDez, Dan V. Nicolau
This study conducted in vitro experimentation using microvascular tissue-like structures to examine the dynamics of interfacial forces leading to gas bubble cessation, with the objective of providing a medical guideline for preventing gas embolism.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC01052J, Paper

Wenxin Wang, Yiyuan Liu, Zhikai Yao, Dengbo Chen, Yue Tang, Jingwei Cui, Jiangjiang Zhang, Hong Liu, Zikai Hao
A depression-on-gut-chip (DoGC) is prepared and enables extended co-culture of aerobic human intestinal epithelial cells and anaerobic gut microbiota, and allows direct study of interactions between human gut microbiota and depression.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00159A, Paper

Lixue Liang, Xueying Wang, Dong Chen, Palaniappan Sethu, Guruprasad A. Giridharan, Yanxia Wang, Yu Wang, Kai-Rong Qin
The best pulsation frequency mode of the RBP would be one that changes every 2–3 times of the cardiac cycle. The proposed in vitro microfluidic model could provide an effective platform to select the best working mode of the RBP for heart failure.
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Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00291A, Paper

Nana Jin, Fan Jiang, Fengzhen Yang, Ying Ding, Ming Liao, Yanbin Li, Jianhan Lin
A colorimetric biosensor was elaboratively designed for fast, sensitive and multiplex bacterial detection on a single microfluidic chip using immune magnetic nanobeads for specific bacterial separation, immune gold@platinum palladium nanoparticles...
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC01116J, Paper

Duomei Tian, Zheng Mao, Li Wang, Xiaochen Huang, Wei Wang, Haoyue Luo, Juan Peng, Yong Chen
Tumor spheroids are cultured in hydrogel microwells with a gravity driven medium flow underneath the membrane on-a-chip. The rocking system is pumpless, powered with a rechargeable battery, and programmable with a built-in microprocess.
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