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Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation




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Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation




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Author Correction: Metabolic activity analyses demonstrate that Lokiarchaeon exhibits homoacetogenesis in sulfidic marine sediments




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Why the Most Important Idea in Behavioral Decision Making Is a Fallacy

The popular idea that avoiding losses is a bigger motivator than achieving gains is not supported by the evidence




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Global Warming Linked to Higher Suicide Rates across North America

A 1 degree Celsius rise corresponded to a 1.4 percent increase in suicides




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Faculty Positions at IDG/McGovern Institute for Brain Research at Peking University

Applications are invited for Principal Investigator (PI) positions at IDG/McGovern Institute for Brain Research at PKU. Positions are open at all ranks from Assistant, Associate to Full Investigator ship.
The Institute was established in 2012 with support from Peking University, IDG and Patrick J. McGovern and Lore Harp McGovern, who are committed to improving human welfare, communication and understanding through their support for neuroscience research. The Institute consists of neural and c…




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Faculty Positions at IDG/McGovern Institute for Brain Research at Peking University

Applications are invited for Principal Investigator (PI) positions at IDG/McGovern Institute for Brain Research at PKU. Positions are open at all ranks from Assistant, Associate to Full Investigator ship.
The Institute was established in 2012 with support from Peking University, IDG and Patrick J. McGovern and Lore Harp McGovern, who are committed to improving human welfare, communication and understanding through their support for neuroscience research. The Institute consists of neural and c…




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Faculty Positions at IDG/McGovern Institute for Brain Research at Peking University

Applications are invited for Principal Investigator (PI) positions at IDG/McGovern Institute for Brain Research at PKU. Positions are open at all ranks from Assistant, Associate to Full Investigator ship.
The Institute was established in 2012 with support from Peking University, IDG and Patrick J. McGovern and Lore Harp McGovern, who are committed to improving human welfare, communication and understanding through their support for neuroscience research. The Institute consists of neural and c…




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Clinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma




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Potential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors




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Rheumatoid arthritis Primer — behind the scenes




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Effectiveness of the adjunctive use of ozone and chlorhexidine in patients with chronic periodontitis




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Comparative efficacy of a hydroxyapatite and a fluoride toothpaste for prevention and remineralization of dental caries in children




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Clinical and radiographic evaluation of indirect pulp treatment of young permanent molars using photo-activated oral disinfection versus calcium hydroxide: a randomized controlled pilot trial




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Author Correction: Genetic circuit design automation for the gut resident species <i>Bacteroides thetaiotaomicron</i>




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Effect of simulated microgravity on the antidiabetic properties of wheatgrass (<i>Triticum aestivum</i>) in streptozotocin-induced diabetic rats

npj Microgravity, Published online: 24 February 2020; doi:10.1038/s41526-020-0096-x

Effect of simulated microgravity on the antidiabetic properties of wheatgrass (Triticum aestivum) in streptozotocin-induced diabetic rats




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Author Correction: Guidance for quantitative confocal microscopy




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Cellular thermal shift assay for the identification of drug–target interactions in the <i>Plasmodium falciparum</i> proteome




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Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy




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COVID-19 outcomes in patients with hematologic disease




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High rate of durable remissions post autologous stem cell transplantation for core-binding factor acute myeloid leukaemia in second complete remission




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COVID-19, HCT and wine




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Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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Dermatophagoides pteronyssinus peptidase 1 (DERP1)

In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma.




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Glutathione peroxidase 4 (GPX4)

Mouse studies suggest inhibiting ferroptosis could help treat ischemia/reperfusion injury in the liver and kidney.




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Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4

Mouse studies suggest chemically modified carbohydrate conjugates could be useful as antigens for the development of cancer vaccines.




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Epidermal growth factor receptor 1 (EGFR1; ErbB1; HER1); HER2 (EGFR2; ErbB2; neu); HER3 (EGFR3; ErbB3); VEGF

Tumor cell and mouse studies suggest tetravalent antibodies that target four different antigens could help treat cancers resistant to HER-targeted therapies.




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Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K)

Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy.




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Translational tidbits

Yabao and MRC Technology partner in PD; charities form Neuro-MAP to insource pharma's abandoned compounds; Singapore creates a diagnostic hub; a roundup of public-private partnerships.




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Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling




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Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity




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Bridging naïve and primed pluripotency




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Superfluid coating




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Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism




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Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization




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Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities




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Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys




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A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies




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Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear




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Author Correction: Insights into parathyroid hormone secretion




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Obesity affects skeletal muscle ketone oxidation




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Obesity and impaired metabolic health in patients with COVID-19




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Sweet signals — gut–brain circuit for sugar identified




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Nanoscale nights of COVID-19




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Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis




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Incidence of acute spinal cord injury in South Korea does not reflect a sizable number of traumatic spinal cord injuries




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A more accurate incidence of acute spinal cord injury in South Korea can be estimated by the national health insurance system