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After Almost Dying, Jeremy Renner's Back

On April 11, Hollywood star Jeremy Renner attended the premiere of his series Rennervations in Los Angeles.




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Ali Wong Thanks Ex-Husband For Globe Win

American stand-up comedian, actress, writer, producer, and director Ali Wong has won the 2024 Golden Globe for Best Actress in a Limited Series for her performance as Amy Lau in the Netflix series, Beef.




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Amy Jackson Gets Engaged!

In the images, Ed can be seen proposing to Amy on bended knee in Switzerland.




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The Song That Made Everyone Cry At The Oscars

Singer Billie Eilish moved everyone to tears when she performed the Barbie soundtrack, What Was I Made For?, at the Oscars 2024.




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The impact of gas purity on observed reactivity with NO using inductively coupled plasma tandem mass spectrometry

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01227E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Amanda D. French, Kirby P. Hobbs, Richard M Cox, Isaac J. Arnquist
Interference removal in inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) is strongly dependent on the gas selected for use within the collision/reaction cell.
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Surface-enhanced Raman scattering enhancement using a hybrid gold nanoparticles@carbon nanodot substrate for herbicide detection

Analyst, 2024, 149,5277-5286
DOI: 10.1039/D4AN00649F, Paper
Open Access
Naghmeh Aboualigaledari, Anitha Jayapalan, Panesun Tukur, Mengxin Liu, Frank Tukur, Yanling Zhang, Gerald Ducatte, Madan Verma, Janet Tarus, Simona E. Hunyadi Murph, Jianjun Wei
Hybrid nanoparticles composed of gold nanoparticles and carbon nanodots provide great signal amplification in SERS detection of herbicide molecules.
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Revealing the heterogeneous catalytic kinetics of PtRu nanocatalysts at the single particle level

Analyst, 2024, 149,5184-5190
DOI: 10.1039/D4AN01017E, Paper
Open Access
Bowei Zhang, Dezheng Zhang, Jinpeng Bao, Ce Han, Ping Song, Weilin Xu
The difference in kinetic information among PtRu bimetallic nanocatalysts, Pt and Ru monometallic nanocatalysts is revealed by the single-molecule fluorescence technique.
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Engineering fluorescent NO probes for live-monitoring cellular inflammation and apoptosis

Analyst, 2024, 149,5306-5312
DOI: 10.1039/D4AN00747F, Paper
Qun Wu, Chengbin Liu, Yifan Liu, Tao Li
A fluorescent probe for live-cell imaging of nitric oxide (NO) allows for sensitive detection of NO in cancer cells, thereby enabling real-time monitoring of doxorubicin-induced apoptosis and lipopolysaccharide-triggered inflammatory responses.
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A cerium-doped tungsten trioxide-functionalized sensing platform for photoelectrochemical detection of ascorbic acid with high sensitivity

Analyst, 2024, 149,5206-5212
DOI: 10.1039/D4AN01165A, Paper
Xueying Zhu, Tikai Liang, Dianping Tang
A highly efficient photoelectrochemical (PEC) strategy was proposed for the determination of ascorbic acid (AA).
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An ultra-sensitive ammonia sensor based on a quartz crystal microbalance using nanofibers overlaid with carboxylic group-functionalized MWCNTs

Analyst, 2024, 149,5191-5205
DOI: 10.1039/D4AN01061B, Paper
Ahmad Hasan As'ari, Rizky Aflaha, Laila Katriani, Ahmad Kusumaatmaja, Iman Santoso, Rike Yudianti, Kuwat Triyana
Utilizing the specific interaction between carboxylic groups and ammonia gas has led to the development of an ultra-sensitive ammonia sensor based on a quartz crystal microbalance using nanofibers overlaid with carboxylic group-functionalized MWCNTs.
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Reference-free quantitative mass spectrometry in the presence of nonlinear distortion caused by in situ chemical reactions among constituents

Analyst, 2024, 149,5320-5328
DOI: 10.1039/D4AN00961D, Paper
Yusuke Hibi
Nonlinear reference-free analysis in pyrolysis-MS enables accurate compositional analysis even in reactive and interactive systems.
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Detection of several volatile organic compounds through Ar+ induced chemical ionisation using inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS)

Analyst, 2024, 149,5174-5183
DOI: 10.1039/D4AN00996G, Paper
Takafumi Hirata, Kyoko Kobayashi, Hui Hsin Khoo, Osamu Shikino, Hisashi Asanuma
A new analytical technique for detection of organic compounds using inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS) is described.
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Utilizing solid-state nanopore sensing for high-efficiency and precise targeted localization in antiviral drug development

Analyst, 2024, 149,5313-5319
DOI: 10.1039/D4AN00946K, Paper
Wei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie Sha
The efficient identification and validation of drug targets are paramount in drug discovery and development.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A sulphide resistant Ag|AgCl reference electrode for long-term monitoring

Analyst, 2024, 149,5225-5231
DOI: 10.1039/D4AN01076K, Paper
Open Access
David S. Macedo, Mikko Vepsäläinen, Theo Rodopoulos, Stephen Peacock, Conor F. Hogan
Solid state reference electrodes (SSREs) with suspended AgCl are resistant to sulphide poisoning. Sulphide species are precipitated as Ag2S, inhibiting their diffusion through the polymer composite.
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Automatic detection of fluorescent droplets for droplet digital PCR: a device capable of processing multiple microscope images

Analyst, 2024, 149,5213-5224
DOI: 10.1039/D4AN01028K, Paper
Kaihao Mao, Ye Tao, Wenshang Guo, Qisheng Yang, Meiying Zhao, Xiangyu Meng, Yinghao Zhang, Yukun Ren
An automated microscope image detection device (A-MMD) is designed to detect fluorescent droplets in droplet digital PCR images captured by multiple microscopes.
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Storing liquid chromatographic separations on surface energy traps: decoupling the LC and the mass spectrometer

Analyst, 2024, 149,5336-5343
DOI: 10.1039/D4AN00828F, Paper
Timothy T. Salomons, David Simon, Richard Oleschuk
A micro-fractionation device to archive liquid chromatographic separations on an array of surface energy traps.
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A highly sensitive and reproducible fluorescence sensor for continuously measuring hydrogen peroxide at the sub-ppm level

Analyst, 2024, 149,5353-5359
DOI: 10.1039/D4AN00975D, Paper
Yang Yang, Rui Jiang, En-lai Yang, Jiahao Liang, Ying Xu, Xu-dong Wang
Highly sensitive and reversible fluorescence H2O2 sensor with a limit of detection of 0.02 ppm had been developed. The sensor responded rather fast, had high stability, and can be massively produced with good batch-to-batch consistency.
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Surface-enhanced Raman spectroscopy with single cell manipulation by microfluidic dielectrophoresis

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00983E, Paper
Kwanhwi Ko, Hajun Yoo, Sangheon Han, Won Seok Chang, Donghyun Kim
The combination of dielectrophoresis and surface-enhanced Raman spectroscopy provides an effective method for analyzing the Raman characteristics and the dielectrophoretic behavior of polystyrene beads and U-87MG cells in a microfluidic environment.
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The development of a method to produce diagnostic reagents using LaNiO3 nanospheres and their application in nanozyme-linked immunosorbent assay for the colorimetric screening of C-reactive protein with high sensitivity

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01160K, Paper
Maria Nikitina, Pavel Khramtsov, Stepan Devyatov, Rishat Valeev, Marina Eryomina, Andrey Chukavin, Mikhail Rayev
LaNiO3 nanosphere-based NLISA has been demonstrated for the first time. The assay enables the CRP effective detection with high sensitivity.
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Ti-based MOF nanosheets as a mass spectrometry imaging matrix for low molecular weight compounds to reveal the spatiotemporal content changes of hepatotoxic components during the processing of Polygonum multiflorum

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00964A, Paper
Feng-yan Kuang, De-jun Hu, Lu Wang, Fei Chen, Guang-ping Lv
The selection of the matrix is crucial for matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI).
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Phenoxy-1,2-dioxetane-Based Activatable Chemiluminescent Probes: Tuning of Photophysical Properties for Tracing Enzymatic Activities in Living Cells

Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01082E, Critical Review
Open Access
Jagpreet Singh Sidhu, Gurjot Kaur, Atharva Rajesh Chavan, Mandeep Chahal, Rajeev Taliyan
The use of chemiluminophores for tracing enzymatic activities in live-cell imaging has gained significant attention, making them valuable tools for diagnostic applications. Among various chemiluminophores, the phenoxy-1,2-dioxetane scaffold exhibits significant...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Advancing triage of acute lymphoblastic leukaemia subtypes diagnosis: label-free Raman spectroscopy for precise single-cell phenotyping and subtype classification

Analyst, 2024, 149,5443-5454
DOI: 10.1039/D4AN00956H, Paper
Patrycja Leszczenko, Anna M. Nowakowska, Patrycja Dawiec, Karolina Czuja, Justyna Jakubowska, Marta Zabczynska, Agata Pastorczak, Kinga Ostrowska, Szymon Tott, Wojciech Mlynarski, Malgorzata Baranska, Katarzyna Majzner
Acute lymphoblastic leukaemia (ALL) is a complex disease in pediatric oncology, necessitating accurate diagnostic strategies for effective treatment planning.
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Advancing cerumen analysis: exploring innovative vibrational spectroscopy techniques with respect to their potential as new point-of-care diagnostic tools

Analyst, 2024, 149,5381-5393
DOI: 10.1039/D4AN00868E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Edoardo Farnesi, Matteo Calvarese, Chen Liu, Carl Messerschmidt, MohammadSadegh Vafaeinezhad, Tobias Meyer-Zedler, Dana Cialla-May, Christoph Krafft, Jonas Ballmaier, Orlando Guntinas-Lichius, Michael Schmitt, Jürgen Popp
The study demonstrates the potential of advanced vibrational spectroscopy to reveal the complex molecular composition of cerumen, suggesting its promising application as a non-invasive diagnostic tool for identifying disease-related biomarkers.
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Electrochemical and imaging evaluations of electrochemically activated screen-printed gold electrodes

Analyst, 2024, 149,5401-5410
DOI: 10.1039/D4AN00990H, Paper
Nor Dyana Zakaria, Ibrahim Luqman Salih, Hairul Hisham Hamzah, Turgut Sönmez, Muhamad Huzaifah Omar, Noorhashimah Mohamad Nor, Khairunisak Abdul Razak, Venugopal Balakrishnan
The graphic abstract displays the integration of the SPGE measurement system with an electrochemical cell-based 3D printing to evaluate the electrochemical behaviors and 3D images of both unactivated and activated SPGEs.
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Selection of DNA aptamers for detecting metronidazole and ibuprofen: two common additives in soft drinks

Analyst, 2024, 149,5482-5490
DOI: 10.1039/D4AN01186D, Paper
Jin Wang, Xiangmei Li, Hongtao Lei, Juewen Liu
Using capture-SELEX, short aptamers for metronidazole and ibuprofen were isolated and they can be used for the detection of these drugs illicitly added to soft drinks.
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Evaluating protocols for reproducible targeted metabolomics by NMR

Analyst, 2024, 149,5423-5432
DOI: 10.1039/D4AN01015A, Paper
Darcy Cochran, Panteleimon G. Takis, James L. Alexander, Benjamin H. Mullish, Nick Powell, Julian R. Marchesi, Robert Powers
Evaluating how sample preparation methods and data analysis platforms impact measured metabolite concentrations underscores the need for a universal consensus in the followed approaches for metabolomics data analysis.
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Screen printed 3D microfluidic paper-based and modifier-free electroanalytical device for clozapine sensing

Analyst, 2024, 149,5411-5422
DOI: 10.1039/D4AN01136H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mohammad Hossein Ghanbari, Markus Biesalski, Oliver Friedrich, Bastian J. M. Etzold
Screen printing was employed for the first time to examine the effect of electrode size and arrangement on the performance of a microfluidic paper-based electroanalytical device for clozapine sensing.
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A nano-biosensing platform based on CuS-BSA for label-free fluorescence detection of Escherichia coli

Analyst, 2024, 149,5394-5400
DOI: 10.1039/D4AN01060D, Paper
Xiaoqing Zhang, Shanglin Li, Mei Liu
A fluorescence biosensing strategy was developed based on CuS-BSA for sensitive and rapid detection of Escherichia coli.
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Effects of media composition and light exposure on the electrochemical current response during scanning electrochemical microscopy live cell imaging

Analyst, 2024, 149,5555-5562
DOI: 10.1039/D4AN01075B, Paper
Nikita Thomas, Mengzhen Lyu, Jadon Khouv, Dhésmon Lima, Sabine Kuss
The cellular electrochemical current response is impacted by media composition and light exposure during scanning electrochemical microscopy (SECM).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Probing the role of ligation and exonuclease digestion towards non-specific amplification in bioanalytical RCA assays

Analyst, 2024, 149,5491-5503
DOI: 10.1039/D4AN00866A, Paper
Vandana Kuttappan Nair, Chandrika Sharma, Shrawan Kumar, Mrittika Sengupta, Souradyuti Ghosh
Comprehensive quantitative analysis of various ligation and digestion conditions to identify and minimize non-specific amplification in RCA bioanalytical methods.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Imaging specific proteins in living cells with small unnatural amino acid attached Raman reporters

Analyst, 2024, 149,5476-5481
DOI: 10.1039/D4AN00758A, Paper
Erli Cai, Yage Chen, Jing Zhang, Haozheng Li, Yiran Li, Shuai Yan, Zhiyong He, Quan Yuan, Ping Wang
For living HeLa cells, we report a small and minimally-invasive Raman reporter (about 2 aa and <1 kDa), which can be site-specifically introduced into proteins by genetic codon expansion combined with tetrazine ligation.
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Designing a novel paper-based microfluidic disc for rapid and simultaneous determination of multiple nutrient salts in water

Analyst, 2024, 149,5563-5571
DOI: 10.1039/D4AN01127A, Paper
Zhentao Sun, Youquan Zhao, Yameng Liu, Chen Chen, Hao Chen
A paper-based microfluidic disc is used for the rapid determination of various nutrients in water.
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Liquid saliva-based Raman spectroscopy device with on-board machine learning detects COVID-19 infection in real-time

Analyst, 2024, 149,5535-5545
DOI: 10.1039/D4AN00729H, Paper
Open Access
Katherine J. I. Ember, Nassim Ksantini, Frédérick Dallaire, Guillaume Sheehy, Trang Tran, Mathieu Dehaes, Madeleine Durand, Dominique Trudel, Frédéric Leblond
Raman spectroscopy and machine learning is used in combination to detect COVID-19 positive saliva in liquid form.
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Electrochemical Sensing of Sodium ions present in Bovine Serum using 4-tert Butylcalix[4]arene as Receptor

Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01297F, Paper
Adrian Ebenazer Paul, Gaurav Gaur, Abdullah Alswieleh, Jerry J. Wu, Sambandam Anandan
The concentration of sodium ions can cause severe imbalances (high pressure on blood vessels, swelling of the muscular tissues, and misfunctioning of the whole nervous system) to the system in...
The content of this RSS Feed (c) The Royal Society of Chemistry




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An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and a one-dimensional neural network combining ResNet and SENet

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00784K, Paper
Liang Ma, Wenqing Gao, Xiangyang Hu, Dongdong Zhou, Chenlu Wang, Jiancheng Yu, Keqi Tang
An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and 1D neural network combining ResNet and SENet is proposed and successfully applied to the diagnosis of ovarian cancer with high accuracy and strong fitting ability.
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Evaluation of extracellular vesicle aggregation by single vesicle analysis

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01112K, Paper
Johan Yi, Suyeon Kim, Chungmin Han, Jaesung Park
A TIRF microscopy-based method for single vesicle aggregation analysis enables precise assessment of EV aggregation under various conditions, enhancing EV characterization and functional analysis.
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Exploring gunshot residue detection in fingerprints by functionalized particle-coupled matrix-assisted laser desorption/ionization mass spectrometry

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01260G, Paper
Sunil S. Adav, Yan Wen Crystal Tan, Choon Teck Low, Song Wei Loo, Ridhwan Yusoff, Archana Gautam, Yuk Lin Yong, Chiew Yung Yang, Chin Chin Lim, Kee Woei Ng
In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction.
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Structural determination of fructooligosaccharides and raffinose family oligosaccharides using logically derived sequence tandem mass spectrometry

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00872C, Paper
Chia Yen Liew, Wun-Long Li, Chi-Kung Ni
Logical procedures for structural determination of fructooligosaccharides and raffinose family oligosaccharides.
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A Novel Light-Harvesting ZIF-9-TCPP as a Promising FRET-based Ratiometric Fluorescence Probe for Sperm Mobility

Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01305K, Paper
Yi-Xuan Li, Yu-Xuan Dai, Ju-Zheng Wang, Jérôme Chauvin, Xueji Zhang, Serge Cosnier, Robert Marks, Dan Shan
The concentration of zinc ions in semen is significantly correlated to the sperm viability and male fertility. In this work, a reliable ratiometric fluorescence probe (ZIF-9-TCPP) based on the efficient...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rapid lung ventilation MRI using parahydrogen-induced polarization of propane gas

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01029A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Md Raduanul H. Chowdhury, Clementinah Oladun, Nuwandi M. Ariyasingha, Anna Samoilenko, Tarek Bawardi, Dudari B. Burueva, Oleg G. Salnikov, Larisa M. Kovtunova, Valerii I. Bukhtiyarov, Zhongjie Shi, Kehuan Luo, Sidhartha Tan, Juri G. Gelovani, Igor V. Koptyug, Boyd M. Goodson, Eduard Y. Chekmenev
The feasibility of ultrafast (1.7 s) ventilation MRI with a 1 × 1 × 50 mm3 voxel size is demonstrated using hyperpolarized propane gas contrast agent in excised rabbit lungs on a 0.35 T clinical MRI scanner without any scanner modification.
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Towards high-resolution water isotope analysis in ice cores using laser ablation – cavity ring-down spectroscopy

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01054J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Eirini Malegiannaki, Pascal Bohleber, Daniele Zannoni, Ciprian Stremtan, Agnese Petteni, Barbara Stenni, Carlo Barbante, Bo M. Vinther, Vasileios Gkinis
A new micro-destructive technique for high-resolution water isotope analysis of ice samples using a Laser Ablation (LA) system coupled with a Cavity Ring Down Spectrometer (CRDS) is presented.
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The Big B way of branding



  • A J Vinayak

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Behind the glow: unveiling the nature of NanoLuc reactants and products

Phys. Chem. Chem. Phys., 2024, 26,27447-27458
DOI: 10.1039/D4CP02551B, Paper
Alessandro Bonardi, Michele Turelli, Giorgio Moro, Claudio Greco, Ugo Cosentino, Carlo Adamo
Among all the possible candidates involved in the NanoLuc bioluminiescnce, this computational analysis identifies the enol tautomer of furimazine as a probable reactive species and the zwitterionic forms of furimamide as the luminescent product.
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In silico validation of allosteric inhibitors targeting Zika virus NS2B–NS3 protease

Phys. Chem. Chem. Phys., 2024, 26,27684-27693
DOI: 10.1039/D4CP02867H, Paper
Yeng-Tseng Wang, Yuan-Chin Hsieh, Tin-Yu Wu
The Zika virus (ZIKV), a member of the Flaviviridae family, poses a major threat to human health because of the lack of effective antiviral drugs.
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A time-independent, variational method for studying the photodissociation of triatomic molecules

Phys. Chem. Chem. Phys., 2024, 26,27519-27529
DOI: 10.1039/D4CP02771J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Marco Pezzella, Georgi Mitev, Sergei N. Yurchenko, Jonathan Tennyson, Alexander O. Mitrushchenkov
The photodissociation of molecules is becoming an increasingly important factor to consider in the evolution of exoplanets' atmospheres orbiting around UV-rich stars, as it leads to the enrichment of atmospheric complexity.
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The effect of hydrogen bonding on the π depletion and the π–π stacking interaction

Phys. Chem. Chem. Phys., 2024, 26,27431-27438
DOI: 10.1039/D4CP02889A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Usman Ahmed, Dage Sundholm, Mikael P. Johansson
Calculations on molecules with self-complementary hydrogen bonding show that hydrogen bonds increase the energy of π–π stacking interactions.
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Comparing coupled cluster and composite quantum chemical methods for computing activation energies and reaction enthalpies of radical propagation reactions

Phys. Chem. Chem. Phys., 2024, 26,27536-27543
DOI: 10.1039/D4CP03676J, Paper
Timothy B. Huber, Ralph A. Wheeler
The accuracy of DLPNO-CCSD(T)/CBS and composite methods G3(MP2)-RAD and CBS-RAD is assessed against CCSD(T)/aug-cc-pVTZ for activation energies and reaction enthalpies in hydrocarbon radical addition reactions relevant to free radical polymerization.
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An in-depth investigation of lead-free KGeCl3 perovskite solar cells employing optoelectronic, thermomechanical, and photovoltaic properties: DFT and SCAPS-1D frameworks

Phys. Chem. Chem. Phys., 2024, 26,27704-27734
DOI: 10.1039/D4CP02974G, Paper
Md. Tarekuzzaman, Mohammad Hasin Ishraq, Md. Shahazan Parves, M. A. Rayhan, Sohail Ahmad, Md. Rasheduzzaman, K A Al Mamun, M. Moazzam Hossen, Md. Zahid Hasan
Crystal structure of KGeCl3 and the design configuration of the KGeCl3-based PSC.
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Machine-learning-accelerated structure prediction of PtSnO nanoclusters under working conditions

Phys. Chem. Chem. Phys., 2024, 26,27624-27632
DOI: 10.1039/D4CP03769C, Paper
Fanke Zeng, Wanglai Cen
Credible property calculations based on the structure prediction of multi-component catalyst clusters under working conditions via a machine-learning-accelerated genetic algorithm and ab initio thermodynamics approach.
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Hole-states in Li doped NiO: doping dependence of Zhang-Rice spectral weight

Phys. Chem. Chem. Phys., 2024, 26,27735-27740
DOI: 10.1039/D4CP03373F, Paper
Suman Mandal, Krishnakumar S. R. Menon
The structural and spectroscopic evolution of Li-doped NiO, along with the behavior of doped hole states, are investigated using XRD and XAS.
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