A keyboard with adjustable touch for a musical instrument, each key being a lever divided into front and rear arms, front arm forms on its upper part an operation surface and its lower part interacts with a centering guide, and the rear arm comprises, on its upper part, a counterweight and its lower part interacts with a stop each key comprises a key magnet (KM) mounted on the rear side, facing another magnet (SM) that is mounted on a regulation device which is affixed to the musical instrument chassis, the magnets (KM and SM) are substantially placed face to face, opposed by their equivalent polar faces, the relative position they have to each other is set by the regulation device and generating the effect on the keyboard touch.

A surface covering kit is disclosed, comprising a plurality of generally rectangular panels (100). Each panel is provided with grooves (301, 302, 301', 302') forming an insertion channel (303) when two panels (100) are laid next to each other along their transverse sides (105, 105') in a common laying plane (101). An extraneous locking element (210) is received by the insertion channel (303), the extraneous locking element (210) having a longitudinal dimension and a cross-section perpendicular to said longitudinal dimension which forms a cross with at least four cross arms. The corresponding cross arms of the insertion channel have two parallel flank surfaces (1603, 1604) each, and each of the cross arms is oriented diagonally in a plane perpendicular to the panel plane (102).

An apparatus for filling joints in precast concrete structures includes a core that has exceptionally low creep and conforms to ASTM D 1752 made of controlled particle size composites of recycled cellular rubber and plastic materials in the form of a rectangular slab. Holes are drilled through a central area and countersink recesses are formed around the holes. An outer coating of a thermoplastic polyurethane/polyurea elastomer system of a thickness of 0.075 inch covers the slab and countersink recesses. The coated core is abrasion and UV resistant while having the creep characteristics needed to make a dam expansion joint filler.

A resilient seal for mobile living quarters around a slide out room that includes a pair of attaching members extending along the inside and outside surfaces of the main living area wall at an aperture through which the slide out room moves and further includes a connecting member extending between the attaching members and along the edge of the wall defining the aperture. A wiper seal extends from the connecting member to flex against the walls of the slide out room, and the connecting member further includes an accordion pleat for adjusting the distance between the attaching members to thereby accommodate walls of different thicknesses.

A composite shield comprises a panel including an outer thin metallic strike surface layer, a highly strain rate hardening polymer layer and an inner structural armor plate layer. The structural armor plate layer has a multiplicity of traversing ports. The traversing ports have sufficient lateral area to allow deformation of the thin metallic strike surface layer and highly strain rate hardening polymer layer through the structural armor plate layer on the occurrence of explosive blast.

A method and device are presented that creates a channel adjacent a nailing flange of a window in between the window and the rough opening that receives the window. The channel is created by establishing a barrier that prevents foam insulation inserted into the space between the window and the rough opening from reaching the nailing flange. The channel then ensures proper drainage of water that enters the window cavity down to the window sill. A gasket is presented that can be attached to the window or the rough opening to create the barrier. Alternatively, a disintegrating object or a wicking object can be used to impede the flow of insulation foam and to create the appropriate channel. The present invention is equally applicable to doors or other framed objects received into the exterior shell of a building.

A suspended ceiling system for a building structure includes a plurality of parallel struts for supporting a plurality of parallel vanes suspended from the struts in perpendicular relationship thereto. The vanes can be suspended in downwardly spaced relationship to the struts or in contiguous relationship therewith and occur in different forms including illuminated vanes, adjustable vanes and the like.

The present disclosure provides devices for preventing or absorbing fluid (e.g., sweat) and/or odors from the intergluteal cleft of a subject. In some embodiments, the present disclosure provides devices for treating or preventing hemorrhoids and methods of using same.

A system and method for creating a medicated atmosphere in an organ, or body cavity is disclosed. The system includes a flexible nebulization catheter that can be manipulated during use, a device for the introduction of the nebulization catheter, a medication delivery apparatus configured to control delivery of a medication to the catheter, a gas delivery apparatus in communication with the catheter, a gas pressure relief apparatus configured to relieve pressure in the organ or body cavity, and a central controller. The system may include a liquid source having a mixture of hyaluronic acid and heparin that, in conjunction with the nebulizing catheter, are designed to generate an aerosol with a particle size of 10-25 microns in a body cavity. The method includes providing an aerosol of anti-adhesive medication to an organ or body cavity while controlling overall pressure in the organ or cavity.

A positive exhalation pressure device (1) is described. The device (1) comprises a housing (2) having an annular chamber (5), a chamber inlet (6) configured to permit air into the chamber, a chamber outlet (7) configured to permit air out of the chamber, and a mouthpiece (8) in fluid communication with the chamber inlet. A movable body such as a ball (3) is disposed in the housing within the annular chamber and configured to revolve around the annular chamber in response to flow of air through the chamber from the chamber inlet to the chamber outlet. The movable body is configured to at least partially block the chamber outlet as it revolves around the annular chamber causing cyclical fluctuations in airflow resistance.

In certain example embodiments, a system and/or method of guiding transitions between therapy modes in connection with the treatment and/or diagnosis of a patient for a respiratory disorder is/are provided. Respiratory disorder treatment according to a first therapy mode is provided. Input indicating a second therapy mode to be transitioned to following provision of the first therapy mode is received, with the second therapy mode being different from the first therapy mode. At least one default treatment parameter suitable for the second therapy mode is assigned or calculated. Each default treatment parameter of the second therapy mode is presented, with each default treatment parameter being adjustable by an operator during the presenting. Transitioning from the first therapy mode to the second therapy mode is performed by providing respiratory disorder treatment in accordance with the second therapy mode and each default treatment parameter and any adjustments made thereto prior to the transitioning. Advantageously, the chances of a patient being disturbed by transitioning from mode-to-mode are reduced.

An umbilical system for sourcing and delivering within a flexible protective covering, a plurality of different breathing gasses, safety tether, a plurality of ancillary lines for remotely distributable, documentable, multidirectional, multi-format data/communications acquisition and delivery, personal/situational awareness and ancillary power sources for tool, accessory or device enervation, to a plurality of Users in an adverse environment.

An example method for detecting respiratory disturbances experienced by a subject can include receiving an airflow signal and at least one of an acoustic or vibration signal, where the airflow, acoustic, and/or vibration signals are associated with the subjects breathing. At least one feature can be extracted from the airflow signal and at least one feature can be extracted from at least one of the acoustic or vibration signal. Based on the extracted features, at least one respiratory disturbance can be detected. The respiratory disturbance can be flow limited breath or inspiratory flow limitation (“IFL”).

The invention pertains to positioning a patient in prone position, comprising: positioning a patient in a supine position,attaching a chest body contact sheet to the chest of the patient with an attached inflatable chest cushion in the deflated state,attaching a pelvic body contact sheet to the pelvic region of the patient with an attached inflatable pelvis cushion in the deflated state,transferring the patient from the supine position to a prone position,with the chest body contact sheet attached to the chest of the patient and the pelvic body contact sheet attached to the pelvic region of the patient and the patient in the prone position, inflating the chest cushion and the pelvis cushion, thereby making that the chest cushion and the pelvis cushion together bear the weight of the torso of the patient with the abdominal region of the patient being decompressed. The invention is based on a combination of anatomy and physiology that is used for a reliable positioning the patient, which is safe for the patient and safe, hygienic and user friendly for the medical team.

A method and a control program for operating an anesthesia apparatus, as well as an anesthesia apparatus (12), which operates according to the method are provided. The anesthesia apparatus includes a breathing gas feed unit (22) intended for displacing a breathing gas volume in a breathing circuit (10). A piston (23) brings about the displacement of the breathing gas. Switching over between a first mode of operation and a second mode of operation during the return of the piston (23) allows for a presetting of a corresponding piston return velocity. The piston return velocity depends on a volume flow in an exhalation branch (34) of the breathing circuit (10) in the first mode of operation. The piston return velocity depends on a minimally necessary piston return velocity in the second mode of operation.

A smart oronasal mask for a positive-airway-pressure device includes a mask body and a temperature sensor. The mask body has an air inlet and an air outlet. The temperature sensor is deposited in the mask body and located between the air inlet and the air outlet for sensing a temperature of a mixture formed by gas entering the mask body through the air inlet of the mask body and gas entering the mask body through the air outlet of the mask body. Then the positive airway pressure device adjusts air feed according to the temperature sensed by the temperature sensor in a real-time manner, so as to help keep a patient's respiratory tract clear.

A mask with cushion that has an outer film is disclosed. The film may be self-skinning or a film formed about or glued to the cushion body. In another form the cushion may be formed with at least a portion having a plurality of adjacent voids having honeycomb-like structure.

A patient monitoring system is configured to monitor oxygen saturation and/or oxygenation of a patient's blood. The system is configured to re-oxygenate the patient in response to a determination that the patient's oxygen saturation and/or oxygenation has fallen below a threshold (e.g., if the patient is experiencing hypoxemia). A re-oxygenation routine may include an initial step of rapidly oxygenating the patient, followed by a reduction of oxygenation to make the oxygenation process more gradual. For instance, after the initial step of rapid oxygenation, the patient may be oxygenated with oxygen at an atmospheric level. The system may dynamically adjust the ratio of delivered oxygen versus delivered air, the duration of oxygenation, and the incidence of oxygenation. The system may also adjust the automated delivery of one or more drugs to the patient based on the patient's condition and/or the state of re-oxygenation.

Methods, systems, and apparatuses are described that indicate an amount at which various gas flow rates should be manually adjusted in order to achieve targeted total flow rates and concentration levels.

The invention relates to a method for automatically adjusting a plurality of tunable passive antennas, for instance a plurality of tunable passive antennas of a radio transceiver using several antennas simultaneously. The invention also relates to an automatically tunable antenna array using this method. An automatically tunable antenna array of the invention has 4 user ports, and comprises: 4 tunable passive antennas, the 4 tunable passive antennas operating simultaneously in a given frequency band and forming a multiport antenna array; 4 sensing units; 4 feeders; a signal processing unit delivering a tuning instruction; and a tuning control unit, the tuning control unit receiving the tuning instruction from the signal processing unit, the tuning control unit delivering tuning control signals to the tunable passive antennas, the tuning control signals being determined as a function of the tuning instruction.

A device comprising: a substrate; a transmit antenna fabricated on the substrate and configured to transmit radio-frequency (RF) signals; a receive antenna fabricated on the substrate and configured to receive RF signals; and circuitry, disposed on the substrate and differentially coupled to the transmit and receive antennas, and configured to provide to the transmit antenna RF signals to be transmitted by the transmit antenna and to process RF signals received by the receive antenna, wherein the substrate comprises material for reducing harmonic coupling between the transmit antenna and the receive antenna.

Aspects of the subject disclosure may include, for example, an antenna structure having a feed point for coupling to a dielectric core of a cable that propagates electromagnetic waves without an electrical return path, and a dielectric antenna, substantially or entirely devoid of conductive external surfaces, coupled to the feed point, the dielectric antenna facilitating receipt, at the feed point, the electromagnetic waves for propagating the electromagnetic waves to an aperture of the dielectric antenna for radiating a wireless signal. Other embodiments are disclosed.

Aspects of the subject disclosure may include, for example, a transmission device that includes a transmitter that generates a first electromagnetic wave to convey data. A coupler couples the first electromagnetic wave to a single wire transmission medium having an outer surface, to forming a second electromagnetic wave that is guided to propagate along the outer surface of the single wire transmission medium via at least one guided wave mode that includes an asymmetric or non-fundamental mode having a lower cutoff frequency. A carrier frequency of the second electromagnetic wave is selected to be within a limited range of the lower cutoff frequency, so that a majority of the electric field is concentrated within a distance from the outer surface that is less than half the largest cross sectional dimension of the single wire transmission medium, and/or to reduce propagation loss. Other embodiments are disclosed.

In embodiments of the present invention improved capabilities are described for an antenna-based detection method and system for sensing an environmental change condition. The method and system is adapted such that the states comprising the environmental change condition are capable of being determined at the location of the detection point utilizing only the magnitude component of the antenna impedance as altered by the discrete change in the environmental condition.

An appliance, such as an oven, includes a housing having an internal compartment and an RF antenna. At least a portion of the housing comprises an electrically conductive portion. The antenna includes an active component and a connection to the electrically conductive portion, which serves as a ground plane of the antenna. The housing may include a door assembly having a window that includes the electrically conductive portion in the form of a transparent conductive layer. The door assembly may be detachable and the connection to the antenna may be made by way of capacitive coupling. In an alternative arrangement, the housing includes a light fixture for illuminating the internal compartment, wherein the active component of the antenna is disposed in the light fixture.

An antenna having a passive antenna element that is integrated in a wireless communication chassis, is naturally in resonance, and is galvanically coupled to ground, and a passive indirect antenna element feed that is non-galvanically coupled to the antenna element. If the chassis is foldable, a parasitic element may be located opposite an antenna element feed when the foldable chassis is in at least one of a closed mode and a tablet mode.

A transmission apparatus includes a first metal plate including a first surface, a second surface opposite to the first surface, and a first through hole penetrating from the first surface to the second surface, the first metal plate; a first board being disposed on the first surface side of the first metal plate, the first board including a first patch antenna positioned inside the first through hole; and a second board being disposed on the second surface side of the first metal plate, the second board including a second patch antenna positioned inside the first through hole and opposed to the first patch antenna, wherein an interval between the first patch antenna and the second patch antenna is set in accordance with a distance for wireless communicating between the first patch antenna and the second patch antenna in a near field.

A folded planar antenna device for radio frequency identification (RFID) reading is provided. The folded planar antenna device includes an RFID chip, a conductor member comprising a binocular-shaped slot; and a substrate. The conductor member is mounted on the substrate and the substrate is connected to the RFID chip through the binocular-shaped slot. The folded planar antenna device can be mounted on different objects, such as metal, meat, or liquid container, without being completely de-tuned.

An antenna device includes: an antenna array configured to radiate or receive an electromagnetic wave signal; a feed network configured to connect the antenna array and a signal multiplexer; at least one signal multiplexer configured to divide one path of a signal from the feed network into at least two paths of a signal, or combine at least two paths of a signal to one path of a signal and transmit the one path of a signal to the feed network; and at least two interface modules connected to an active module and configured to receive a signal sent from the passive module or the active module, or send a signal to the active module. The antenna device can be used for sharing the antenna array and other parts in the active antenna systems.

An antenna array includes a plurality of patch antennas including a plurality of layers. Each of the plurality of layers are separated by a distance and each support a portion of the plurality of patch antennas. A plurality of connectors are each associated with one of the plurality of layers and supply a signal for transmission by the associated layer. A feed network on each of the plurality of layers provides a connection between a connector associated with the layer and the portion of the patch antennas located on the layer. Each layer transmits a signal having a different orthogonal function applied thereto that multiplexes each of the signals having a different orthogonal function applied thereto onto a single transmission beam. A parabolic reflector reflects the single transmission beam from the plurality of layers of the antenna array.

A multiplexer structure includes a passive substrate. The multiplexer structure may also include a high band filter on the passive substrate. The high band filter may include a 2D planar spiral inductor(s) on the passive substrate. The multiplexer structure may further include a low band filter on the passive substrate. The low band filter may include a 3D through-substrate inductor and a first capacitor(s) on the passive substrate. The multiplexer structure may also include a through substrate via(s) coupling the high band filter and the low band filter.

A method of manufacturing a thin-film transistor includes forming an oxide semiconductor on a substrate, stacking an insulating layer and a metal layer on the substrate to cover the oxide semiconductor, forming a photosensitive pattern on the metal layer, forming a gate electrode by etching the metal layer using the photosensitive pattern as a mask, where a part of the gate electrode overlaps a first oxide semiconductor region of the oxide semiconductor, forming a gate insulating film by partially etching the insulating layer using the photosensitive pattern as a mask, where the gate insulating film includes a first insulating region with a first thickness under the photosensitive pattern and a second insulating region with a second thickness less than the first thickness, and performing plasma processing on the gate insulating film so that a second oxide semiconductor region of the oxide semiconductor under the second insulating region becomes conductive.

A polymerizable liquid crystal compound represented by Chemical Formula 1: wherein in Chemical Formula 1, groups and variables are the same as defined in the detailed description.

According to one embodiment, a display device includes a liquid crystal display panel, a cover panel on a display surface of the liquid crystal display panel, a backlight unit opposed to the liquid crystal display panel, a case covering the backlight unit and the liquid crystal display panel, and including at least a part fixed to the cover panel, and an adhesive provided on the cover panel along the liquid crystal display panel. The adhesive includes a surface opposite to the cover panel, a first area on the surface, and a second area on the surface, located on an inner side closer to the liquid crystal display panel than the first area. The part of the case is adhered to the second area.

Carbon allotropes, a thin-film transistor array substrate comprising the same, and a display device comprising the same are disclosed. The thin-film transistor array substrate comprising a substrate, a gate electrode on the substrate, a gate insulating film on the gate electrode, an active layer positioned on the gate insulating film and comprising a semiconductor material and a plurality of carbon allotropes, and a source electrode and a drain electrode that make contact with the active layer.

A single molecule sensing or detecting device includes a first electrode and a second electrode separated from the first electrode by a gap. The first electrode and the second electrode have an opening formed therethrough. At least one of the first electrode and the second electrode is functionalized with a recognition molecule. The recognition molecule has an effective length L1 and is configured to selectively bind to a target molecule having an effective length L2. The size of the gap is configured to be greater than L2, but less than or equal to the sum of L1 and L2.

Methods and apparatus for treating an exhaust gas in a foreline of a substrate processing system are provided herein. In some embodiments, a method for treating an exhaust gas in an exhaust conduit of a substrate processing system includes: flowing an exhaust gas and a reagent gas into an exhaust conduit of a substrate processing system; injecting a non-reactive gas into the exhaust conduit to maintain a desired pressure in the exhaust conduit for conversion of the exhaust gas; and forming a plasma from the exhaust gas and reagent gas, subsequent to injecting the non-reactive gas, to convert the exhaust gas to abatable byproduct gases.

The present application discloses methods and apparatus for conversion of quantized vibrational energy. The present application discloses, by driving a medium that comprises arranged nuclei with one or more selected driving frequencies, the arranged nuclei in the medium are induced to oscillate coherently at one or more oscillating frequencies. The mechanical vibrational energy of the oscillating nuclei interacts with the oscillating medium. The interaction between the vibrational energy and the oscillating medium effectuates up-conversion or down-conversion of quantized vibrational energy.

The invention discloses a composite material used for catalyzing and degrading nitrogen oxide and its preparation method and application thereof. The invention of the hollow g-C3N4 nanospheres/reduced graphene oxide composite-polymer carbonized nanofiber material is prepared as follow: 1) the preparation of silica nanospheres; 2) the preparation of hollow g-C3N4 nanospheres; 3) the preparation of graphene oxide; 4) the preparation of surface modified hollow g-C3N4 nanoparticles preparation; 5) the preparation of composites; 6) the preparation of composite-polymer carbon nanofiber material. The raw materials used in the process is low cost and easy to get; the operation of the invention is simple and convenient without the use of expensive equipment in the whole process; the composite has high adsorption efficiency of ppb level nitrogen oxide with good repeatability.

Electrolytic liquid generating device (1) includes laminated body (41) in which conductive film (46) is laminated to be interposed between mutually adjacent electrodes (44, 45), and electrolytic part (40) which electrolyzes liquid. Furthermore, electrolytic liquid generating device (1) includes a passage having inflow port (71) in which liquid to be provided to electrolytic part (40) flows and outflow port (72) from which electrolytic liquid generated in electrolytic part (40) flows out. The passage is formed such that liquid flowing direction (X) crosses laminated direction (Z) of laminated body (41).

A system and method for dehydrating crude oil on a floating production storage and offloading installation include a separator vessel to receive an incoming produced water stream, followed by a flash vessel, a treatment block, a crude oil storage tank, and an electrostatic treater. The treatment block includes a low pressure degasser followed by a compact electrostatic separator pre-treater or a compact electrostatic separator pre-treater followed by a low pressure degasser. The flash vessel and/or the low pressure degasser may employ an inlet cyclonic distributor and demisting cyclones, while the electrostatic treater may employ DUAL FREQUENCY® technology. The separator vessel may be a single horizontal two-phase separator/degasser or two vertical two-phase separator/degassers that operate in parallel with each receiving approximately 50 percent of the incoming produced water stream. The final outlet stream preferably contains no more than 0.5 BS&W and 285 milligrams per liter salt.

Methods are provided for production of a composite layer comprising a plastic foil and a layer deposited directly thereon. A method for production of a composite layer comprising a plastic foil and at least one layer deposited directly onto the plastic foil by means of chemical gas-phase deposition within a vacuum chamber may be provided, wherein the plastic foil has a proportion of at least 20 percent by mass of a metal element or of a semiconductor element, wherein during the layer deposition, at least one monomer is supplied into the vacuum chamber and a plasma is formed within the vacuum chamber. After completed deposition of the layer, at least one surface region of the layer is exposed to accelerated electrons.

A magnetically enhanced low temperature high density plasma chemical vapor deposition (LT-HDP-CVD) source has a hollow cathode target and an anode, which form a gap. A cathode target magnet assembly forms magnetic field lines substantially perpendicular to the cathode surface. A gap magnet assembly forms a magnetic field in the gap that is coupled with the cathode target magnetic field. The magnetic field lines cross the pole piece electrode positioned in the gap. The pole piece is isolated from ground and can be connected to a voltage power supply. The pole piece can have negative, positive, floating, or RF electrical potentials. By controlling the duration, value, and sign of the electric potential on the pole piece, plasma ionization can be controlled. Feed gas flows through the gap between the hollow cathode and anode. The cathode can be connected to a pulse power or RF power supply, or cathode can be connected to both power supplies. The cathode target and substrate can be inductively grounded.

An Al—Te—Cu—Zr alloy sputtering target, comprising 20 at % to 40 at % of Te, 5 at % to 20 at % of Cu, 5 at % to 15 at % of Zr and the remainder of Al, wherein a Te phase, a Cu phase and a CuTe phase are not present in a structure of the target. An object of the present invention is to provide an Al—Te—Cu—Zr alloy sputtering target capable of effectively reducing particle generation, nodule formation and the like upon sputtering and further capable of reducing oxygen contained in the target.

A magnetically enhanced HDP-CVD plasma source includes a hollow cathode target and an anode. The anode and cathode form a gap. A cathode target magnet assembly forms magnetic field lines that are substantially perpendicular to a cathode target surface. The gap magnet assembly forms a cusp magnetic field in the gap that is coupled with the cathode target magnetic field. The magnetic field lines cross a pole piece electrode positioned in the gap. This pole piece is isolated from ground and can be connected with a voltage power supply. The pole piece can have a negative, positive, or floating electric potential. The plasma source can be configured to generate volume discharge. The gap size prohibits generation of plasma discharge in the gap. By controlling the duration, value and a sign of the electric potential on the pole piece, the plasma ionization can be controlled. The magnetically enhanced HDP-CVD source can also be used for chemically enhanced ionized physical vapor deposition (CE-IPVD). Gas flows through the gap between hollow cathode and anode. The cathode target is inductively grounded, and the substrate is periodically inductively grounded.

A film is sputter-deposited on an essentially plane, extended surface of a substrate which has recesses therein, namely at least one of grooves, of holes, of bores, of vias, of trenches. So as to establish on one hand a homogeneous thickness distribution of the film along the addressed surface of the substrate and, on the other hand, a thick film deposition within the recesses, sputter deposition is performed first at a large distance between a sputter surface of a target and the addressed surface of the substrate and then at a reduced distance between the addressed surfaces.

Self-propelling, programmable nanoscopic motors capable of harvesting energy from absorbed photons and undergoing subsequent photoeletrochemical (PEC) reactions are provided. A nanomotor can have a three-dimensional Janus configuration and can sense the direction of a light source. By controlling the zeta potential of different parts of the nanomotor with chemical modifications, the nanomotor can be programmed to show either positive phototaxis or negative phototaxis.

Light-addressable potentiometric sensing units are provided. A light-addressable potentiometric sensing unit comprises a conductive substrate, a metal oxide semiconductor layer, and a sensing layer. The metal oxide semiconductor layer is made of indium gallium zinc oxide, indium gallium oxide, indium zinc oxide, indium oxide co-doped with tin and zinc, tin oxide, or zinc oxide. The wide-band gap characteristic of the metal oxide semiconductor layer enables the light-addressable potentiometric sensing unit to resist the interference from visible light. The light-addressable potentiometric sensing unit therefore exhibits a more stable performance.

A capillary electrophoresis device including a capillary tube, a suction pump for taking liquid, an intake tube whose end is formed vertically downward, a connection block in which there is an intake flow path that holds the end of the capillary tube and connecting the suction pump to the intake tube, a sample storage unit which contains a sample and has an upward opening into which the tip of the intake tube may be inserted, an intake tube access mechanism to insert the tip of the intake tube into the sample storage unit, and a voltage application mechanism that applies an electric potential difference across the capillary tube.

In one aspect, a biological sequencing device comprising a cartridge configured to be removed from the instrument is disclosed. In various embodiments the cartridge can include one or more capillaries suitable for capillary electrophoresis, a reservoir and a pump. In various embodiments the reservoir can contain a separation matrix. In various embodiments the pump can load a capillary with separation matrix. In another aspect the biological sequencing device can include one or more capillaries and an integrated valve assembly. In various embodiments the integrated valve assembly can provide a polymer to the one or more capillaries.