She was born in Rome and reared in the love of Christ. She secretly left her parents' house and traveled by ship to Alexandria, where she found lodging with four virtuous pagan maidens. By her example and counsel these four were in time led to abandon idolatry and embrace Domnica's faith. The five then sailed to Constantinople, where it is said that the Patriarch Nectarius (October 11) was notified of their coming by an angel and met them at the dock. The Patriarch baptized the four maidens himself, giving them the names Dorothea, Evanthia, Nonna and Timothea, then settled them and Domnica in a monastery.   Soon the fame of Domnica's pure life, wise teaching, and wondrous healings spread throughout the city, and even the Emperor Theodosius, with the Empress and his court, came to see her. Soon the crowds made it impossible for her and her sisters to live the heavenly life for which they had entered the monastery; so they relocated the monastery to a remote, demon-haunted location where executions had once commonly been performed, since everyone avoided the area. Here a new monastery was built by order of the Emperor, and the sisters found peace.   Saint Domnica's fame continued, and she became not only a healer but an oracle for the city of Constantinople, prophesying the death of the Emperor Theodosius and the unrest which followed it. She reposed in peace, having first entrusted the care of the monastery to Dorothea. At the moment of her death, the whole monastery was shaken, and those present saw Saint Domnica dressed as a bride, being borne heavenward escorted by a company of white-clad monks and nuns.

He was born around 300 in Egypt and in his youth was a camel driver. While still living in his village, he withdrew to a small cell to devote himself exclusively to ascesis and prayer. When the people there wanted to make him a priest, he fled to another village. There a young woman who was discovered to be pregnant falsely accused Macarius of being the father. Macarius was seized, reviled and beaten, but made no effort to defend himself; instead he took on more work in order to provide for the mother and her child. When his innocence was finally discovered, the townspeople came to ask his forgiveness; but he fled to the desert of Sketis (now called Wadi Natrun). He was then thirty years old, and for the rest of his life he dwelt in the desert.   His humility and detachment from earthly things were so great that once, when he discovered a thief stealing his few possessions, he helped the man load them onto his camel, even pointing out to him the few things he had missed. Once a demon spoke to him thus: "Everything you do, I do too: you fast, but I never eat; you keep vigil, but I never sleep; you only exceed me in one way: your humility. Because of this I am helpless against you." The Saint said that the demons could be put in two categories: those who arouse passions such as anger, lust and greed; and others, much more dreadful, who deceive us by spiritual illusion, blasphemy and heresy.   Saint Macarius soon became known throughout Egypt, and many visitors came to his isolated home. He welcomed all with joy, judging no one and providing hospitality for all. His compassion extended to all, and he prayed even for the damned. Once he found the skull of a pagan priest, which addressed him, saying, "Each time you have pity on us who are in torment, immersed in fire and darkness, we receive a measure of comfort and are allowed to see the faces of our fellow sufferers."   Saint Macarius became a disciple of St Anthony the Great, and in his turn became the spiritual Father of many who came to live near him in the desert. He is considered the founder of the ancient and venerable monastic community at Sketis. At the age of forty he was ordained a priest at the urging of St Anthony, so that he and his brethren would not have to walk the forty miles of desert to Nitria to go to church.   Knowing that he was soon to die, he visited his disciples one last time, saying to them with tears in his eyes, "Let us weep, brethren, so that our eyes flow ceaselessly with tears, before we go to where our tears will scald our bodies." Soon thereafter he reposed. His relics now rest in the Coptic monastery that bears his name. The collection of fifty Spiritual Homilies attributed to St Macarius is a treasury of Orthodox spirituality.

Xenophon was a wealthy senator in Constantinople during the reign of Justinian. He and his wife Mary had two sons, Arcadius and John, to whom they gave every advantage of education. When they were of age, Xenophon sent them both to study law in Berytus (Beirut). But the ship on which they set out was wrecked in a storm, and the two brothers were cast ashore, alive but separated, neither knowing whether the other had survived.   Both brothers gave thanks to God for their salvation and, newly conscious of the vanity of earthly things, both became monks: John in Tyre and Arcadius in Jerusalem. Two years later, having heard no news from his sons, Xenophon made inquiries and found that they had never arrived at Beirut, and that they had seemingly perished in a shipwreck. Giving thanks to God, who gives and takes away, both Xenophon and his wife Mary put on coarse garments and went on pilgrimage to the Holy Land. In Jerusalem, they met the spiritual father of Arcadius, who told them that both their sons were alive and that they would soon see them.   By God's providence, John and Arcadius met one another at Golgotha and, joyfully reunited, spent some time serving Arcadius' holy Elder. Two days later Xenophon and Mary, visiting the Elder, spent time with their two sons but did not recognize them until the Elder revealed their identity. The parents wept for joy and decided immediately to take up the monastic life themselves. Giving away their considerable wealth, the two entered monasteries in the Holy Land. Both parents and sons went far in the life of prayer, being granted the power to work miracles and foreknow future events.

"The life of this saint is wonderful beyond measure and is worth reading in full. What did he not endure to fulfil the Law of God? At the age of eighteen, he went off into a mountain in Cappadocia called the Ark and spent 25 years in fasting, vigils and prayer, and struggling with manifold temptations. When a woman came to tempt him and he saw that he would fall into sin with her, he leapt barefoot into the fire and stood in it until the pain brought forth tears from his eyes and he had killed all lust within himself. When other temptations arose, he fled to a lonely rock in the sea and lived there. When, though, in a shipwreck, a woman swam to the rock, he leapt into the sea intending to drown himself. But a dolphin took him upon its back and brought him, by God'd providence, to the shore. He then decided to make nowhere his permanent home but to travel incessantly. Thus he pased through 164 towns in two years, exhorting and advising the people. He finally arrived in Athens, where he died in 422." (Prologue)

These twelve holy Martyrs suffered in the reign of Diocletian.   "The first of these, Pamphilius, was priest in the church at Caesarea in Palestine; a learned and devout man, he corrected the mistakes of various copiers in the text of the New Testament. He himself copied this saving Book and gave it to any who desired it. The second was a deacon, Valentine, old in years and white with wisdom. He was a great expert in the Holy Scriptures, knowing them by heart. The third was Paul, a respected and eminent man, who had on a previous occasion been cast into the fire for the sake of Christ. With them were five Egyptians, brothers both in blood and soul, who were returning to their native land from serving a sentence in the mines of Cilicia. As they reached the gate of the town of Caesarea they said that they were Christians, and were therefore brought to trial. When asked their names, they replied: 'We have cast away the pagan names given us by our mother, and are called Elias, Isaiah, Jeremiah, Samuel and Daniel.' when asked where they were from, they replied: 'From Jerusalem that is above.' They were all beheaded, and a young man called Porphyrius, who had searched for their bodies to give them burial, suffered soon afterwards. Him they burned. An officer, Seleucus, who had come up to the martyrs and embraced them before the sword descended on their heads, was also burned, and an old man, Theodulus, a servant of the Roman judge, who had embraced one of the martyrs while they were under escort. Lastly Julian, who had kissed the dead bodies of the martyrs and honoured them, followed them in death. So they exchanged the small for the greater, the tawdry for the precious and death for immortality, and went to the Lord in 308." (Prologue)   The Synaxarion concludes, "After the martyrdom of Pamphilius, the leader of the glorious cohort, the impious governor gave orders that his body and those of his companions should be left where they lay as food for carnivorous animals. However by God's Providence, no animal came near their holy relics, which the Christians were able to lay to rest with due honour." The account of these Martyrs was written by Eusebius of Caeserea, Pamphilius' disciple.

He lived at the time of the first persecutions of the holy icons. He was born in Ravenna to a noble family, and became bishop of his native city. Soon his reputation as a true shepherd of Christ's flock spread, and he was elected Bishop of Catania in Sicily. As is so often true even today, the city, though nominally Christian, was plagued by superstition and paganism. The holy bishop set about to turn the people away from error: by his prayers he caused a pagan temple to collapse and built a church on its site, dedicated to the Forty Maryrs of Sebaste. At that time the entire island was under the oppressive rule of a magus named Heliodorus, who used all his magical skills to oppress the people and advance himself. Though he had been taken captive by Imperial order, and condemned to death, he was always able to escape his captors by his occult skills. Saint Leo, who sought the conversion of everyone, did his best to turn the magus to Christ, but to no effect. One day Heliodorus entered the church during the Divine Liturgy, mocking the Mysteries of Christ. The Saint came out of the sanctuary and, casting his omophorion over the mocker, instantly deprived him of his demonic powers. The Prefect of Sicily ordered the magus to be burnt alive. Bishop Leo went to the stake with him, but emerged unmarked without even the smell of fire upon him, while Heliodorus was burnt to ashes.   Saint Leo's fierceness in defense of the Faith was matched by his love and compassion for the poor and defenseless, for whom he poured himself out unceasingly with prayers, alms and visitation. By his prayers he restored sight to the blind and healed the paralyzed. After his repose, his holy relics, which exuded a fragrant myrrh, were venerated in a church that he had founded in honor of Saint Lucia.

He was born at Ephesus around the year 70. St Irenaeus of Lyons, his disciple, says that St Polycarp was 'a disciple of the Apostles and acquainted with those who had seen the Lord.' His parents died as martyrs, and he was given into the care of a devout lady named Callista. As a child, the Saint was so eager to follow the commandments of Christ that he repeatedly emptied his foster-mother's pantry to feed the poor. Since her supplies were always miraculously renewed, Callista changed his name from Pancratius to Polykarpos, meaning 'Much fruit.'   When grown, Polycarp became a disciple of St John the Theologian, and in time became Bishop of Smyrna; it is told that the messages to the Church at Smyrna in the Book of Revelation are addressed to St Polycarp and his flock. He knew St Ignatius of Antioch personally, and some of their correspondence is preserved.   Polycarp led his Church in holiness for more than fifty years, and became known throughout the Christian world as a true shepherd and standard-bearer of the Faith. About the year 154 he traveled to Rome and consulted with Pope Anacletus on the defense of the Faith.   Not long after he returned to Smyrna, a fierce persecution was unleashed against Christians in Asia Minor; along with many others, St Polycarp was arrested, having predicted his imminent martyrdom. (The account of his martyrdom that follows is based on eyewitness accounts gathered immediately after his death.)   On the evening of Holy Friday, soldiers burst into the farmhouse where he was staying. The Bishop welcomed them cheerfully, and ordered that a meal be prepared for them. He was granted some time to pray, and for two hours stood commemorating everyone that he had known and praying for the Church throughout the world. His captors sorrowed that they had come to take such a venerable man, and reluctantly took him to the Proconsul. When urged to deny Christ and save his life, the aged Saint replied, 'For eighty-six years I have been his servant, and he has wronged me in nothing; how can I blaspheme my King and Savior?' Told that he would die by fire if he did not apostatize, Polycarp replied 'You threaten me with a fire that burns for a short time and then goes out, while you know nothing of the fire of the judgment to come and of the everlasting torment awaiting the wicked. Why wait any longer? Do what you will!'   Placed on the pyre, Polycarp lifted his eyes heavenward and gave thanks to God for finding him worthy to share with the holy Martyrs of the cup of Christ. When he had said his Amen, the executioners lit the fire. The eyewitnesses write that the fire sprang up around him like a curtain, and that he stood in its midst glowing like gold and sending forth a delightful scent of incense. Seeing that the fire was not harming him, the executioners stabbed him with a sword. His blood flowed so copiously that it put out the fire, and he gave back his soul to God. His relics were burned by the persecutors, but Christians rescued a few fragments of bone, which were venerated for many generations on the anniversary of his repose.

He was from Decapolis near the Sea of Galilee, and entered monastic life as a youth. When the Emperor Leo the Isaurian began his persecution of the holy icons, Procopius, who had previously spent his life in hiddenness and silence, boldly stood forth to defend the true Orthodox veneration of the icons. For this he was cruelly tortured and imprisoned. When the cruel Leo died and the icons were restored to the churches, Procopius returned to his monastery, where he lived in peace to a great old age. The Prologue concludes, 'In old age, he entered into God's Kingdom, where he beheld with joy the living angels and saints whose images were on the honoured icons on earth.'

"Two friends, John and Sergius, swore brotherhood before the icon of the holy Mother of God in this monastery. John was a rich man, with a five-year-old son, Zachariah. John fell ill, and at his death commended his son to the care of Sergius, and left in Sergius' keeping a large sum of silver and gold for him to hand over to Zachariah when he had grown up. When Zachariah came of age, however, Sergius denied receiving anything from the deceased John. Then Zachariah said: 'Let him swear before the same icon of the most holy Mother of God, in front of which he accepted brotherhood with my late father, that he received nothing from John, and then I will seek nothing more from him.' Sergius agreed, but when he had sworn this and went up to kiss the icon, some force held him back and would not allow him to come near. Then, tormented all at once by a demon, he began to cry out: 'Holy fathers Antony and Theodosius, do not let this merciless angel destroy me!' The demon had attacked him by God's permission. He then told them of all the money which John had left. But when they opened the box, they found double the amount. Taking it, Zachariah gave it to the monastery and was himself tonsured as a monk. He lived a long time and was worthy of God's great gifts, entering peacefully into eternity."

She was a servant of the Jewish wife of the governor of Thessalonica. When she refused to enter the synagogue with her mistress, she was beaten, then locked in a cell until she starved to death. Finally, her mistress ordered her body thrown from the roof of the house and left to lie in the open. Christians took her body and buried it honorably, and the bishop, Alexander, built a church over her grave.