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Newly published set of Test Guidelines

A set of new and updated OECD Test Guidelines was published at the end of July 2015 to test chemicals and identify hazards such as endocrine disruption, serious eye damage, genotoxicity, skin irritation or corrosion.




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Fundamental and Guiding Principles for (Q)SAR Analysis of Chemical Carcinogens with Mechanistic Considerations

The OECD has published fundamental and guiding principles to facilitate the application of QSAR methods to the risk assessment of chemicals. The main focus is on the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches of combining chemoinformatics and bioinformatics.




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Application of Good Laboratory Practice Principles to Computerised Systems

This new Advisory Document replaces the 1995 consensus document on the Application of the Principles of GLP to Computerised Systems. It retains all of the key text from the original 1995 document, but includes new text to reflect the current state-of-the art in this field.




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OECD publishes new and updated Test Guidelines for effects on human health and on environmental species

The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. Every year new and updated Test Guidelines are adopted to meet the regulatory needs in OECD member countries. The most recent Test Guidelines were adopted in July 2016.




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Developmental neurotoxicity: OECD/EFSA experts discuss non-animal test methods

Participants from 15 countries attended the Workshop on Developmental Neurotoxicity: The use of non-animal test methods for regulatory purposes” on 18 October 2016, in Belgium. The event, co-organised by the OECD and the European Food Safety Authority (EFSA), focused on opportunities and challenges related to alternative methods for testing and assessing the DNT potential of chemicals.




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Publications in the series on Pollutant Release and Transfer Registers

This new council act recommends that Member countries take steps to establish, as appropriate, implement and make publicly available a pollutant release and transfer register (PRTR) system using the principles and information set forth in the OECD Guidance Documents on PRTRs.




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Council Act: Revision to the "Decision-Recommendation on the Co-operative Investigation and Risk Reduction of Chemicals"

The Decision-Recommendation on the Co-operative Investigation and Risk Reduction of Chemicals revises and replaces a 1991 Decision-Recommendation of the Council. The Decision-Recommendation is composed of two parts: Part A focuses on the development of harmonised hazard and exposure assessment methodologies for chemicals and Part B focuses on risk prevention and reduction.




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Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption

This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines.




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Sustainable Chemistry

On 6 November 2018, the OECD was awarded the Silver Award in the research category at the 2018 Global Chemical Leasing Award for its report on the Economic Features of Chemical Leasing.




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Considerations for Assessing the Risks of Combined Exposure to Multiple Chemicals

This document outlines various approaches and methodologies for the assessment of risks from combined exposures to multiple chemicals. The document draws from approaches and experience in the regulatory context, and presents elements to consider in the assessment.




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Release of the Global Harmonised Submission Transport Standard (GHSTS) version 2.0

GHSTS is a standardised set of technical specifications for assembling electronic files for pesticide registration in a predefined manner. Once assembled according to the GHSTS, the dossier files can be transferred from a business to a regulatory authority and can be used in a regulatory process. Version 2.0 includes improved lifecycle management of documents over a series of submissions for one pesticide (or other) regulatory action.




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Safety of novel foods and feeds and on the harmonisation of regulatory oversight in biotechnology

A major fruit crop of temperate regions, APPLE is consumed worldwide as fresh fruit, juice and other food products. This consensus document provides science-based key insights for the regulatory assessment of the environmental safety of genetically-engineered products: taxonomy, reproductive biology, genetics, hybridisation and introgression, and ecology.




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The Slow Lane: Sharp satire isn’t all it seems

Caricaturist James Gillray was arrested over a print showing politicians kissing a new royal baby’s backside




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Horace – the best self-help there is

It is that forging and tempering that makes the poet’s utterances strong and flexible




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‘Catullus’ Bedspread’, by Daisy Dunn

An imaginative journey into the life and work of an elusive Roman poet




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Amazon’s phone is about credit, not calls

People seem to resign themselves to innovations they considered dubious at the outset




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OkCupid’s test was a poisoned arrow

A website’s faults do not absolve it from dealing fairly with users




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Tawdry trade tarnishes German justice

The Ecclestone case illustrates that power is migrating away from votes and towards money




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Trouble with trolls is they may be right

Uncivil rantings are not as uninformed as one might assume




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With Ebola, a little panic is healthy

The conditions of managing this crisis are coming to resemble those at Chernobyl




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The Trump Aesthetic: how his tastes will change America

What cultural impact will the incoming president have? Prepare for a mash-up of Sinatra, sports stars and reality TV




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Democrats risk over-reach after midterms

Americans resent inquisitions aimed at depriving them of their elected president




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Publicis CEO on adapting to digital disruptions in advertising

Sadoun: “This is how I work: I go fast, I take risk, I learn, I correct if it’s not good”




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Expedia boss Dara Khosrowshahi on new disrupters

The travel company CEO sees voice search as the next opportunity for growth




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Chubb CEO Greenberg on his winning M&A formula

The son of a towering industry figure is building his own empire




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Christer Gardell, Cevian Capital founder, on clearing out boards

Europe’s biggest activist investor shakes up management teams to unlock hidden value




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Jean-François van Boxmeer, Heineken CEO

The brewery chief has staved off decline with emerging market acquisitions




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Tokyo’s tourism boom is a barometer for Europe’s health

The capital is the cleanest, most orderly and safest bet for spending time in a global city




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The Fast Lane: A Swiss bunker and other border myths

The Swiss bunker mentality has always felt at once quaint, menacing and oddly reassuring




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The Fast Lane: from Swiss post to Swedish retail

A few of late summer’s more frequently asked questions




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The Fast Lane: how newspaper delivery has missed a trick

Many media companies still maintain a direct relationship with readers — but few still have access to foyers




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The Fast Lane: why all the world is going to Lisbon

While other countries spend a fortune attracting ‘influencers’, in Portugal it has happened organically




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Top 5 pension issues for consumers

Tips on how to improve your retirement income




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Seoul party district cluster of cases raises fears lockdown eased too soon

Social distancing reinstated as new cases are linked to one person who might have had contact with 1,500 others




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Experts warn coronavirus will divert resources from killer diseases

Fears for prevention and treatment of other illnesses such as malaria and dengue fever




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Parisian bookseller on edge as reopening looms

After weeks of lockdown, starting again will bring its own challenges for small retailers




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Airlines/social distancing: flights of fancy

In order to square restrictions with profitability, airlines would need to jack up ticket prices threefold




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Trillion-dollar club tightens grip on fund market during crisis

Market leaders such as BlackRock, Vanguard and State Street have gained control of 61% of the industry’s assets




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Foxtons and Restaurant Group criticised over equity raisings

Advisory groups urge shareholders to vote against companies’ actions at AGMs




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No, minister

Valuable insights from Samuel Brittan’s diary during his brief spell in the Department of Economic Affairs




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Who is afraid of currency wars?




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Inflation is a side effect, not the cure

It makes no sense to aim for a high rate in order to create jobs




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This is no time for a UK stimulus

The current period is reminiscent of 1937, when Keynes said the time was wrong to boost spending




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Banish talk of inequality from economics

True equality may not not even be possible in death – Mozart was buried in a paupers’ grave




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Osborne’s last chance to leave his mark

UK chancellor will have to balance his austere instincts against political pressure to ‘do something’




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UK’s gear shift reminiscent of 1970s boom

Samuel Brittan considers parallels in pre-election growth under chancellors Osborne and Barber




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UK’s McCarthyite misjudged frenzy over sex abuse

The police have been far too zealous in dealing with some claims