to A practical guide for the assay-dependent characterisation of irreversible inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00707G, Review ArticleLavleen K. Mader, Jessica E. Borean, Jeffrey W. KeillorKinetic evaluations for assay dependent characterization of irreversible inhibitors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
to SIGMAP: an explainable artificial intelligence tool for SIGMA-1 receptor affinity Prediction By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00722K, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Maria Cristina Lomuscio, Nicola Corriero, Vittoria Nanna, Antonio Piccinno, Michele Saviano, Rosa Lanzilotti, Carmen Abate, Domenico Alberga, Giuseppe Felice MangiatordiDeveloping sigma-1 receptor (S1R) modulators is considered a valuable therapeutic strategy to counteract neurodegeneration, cancer progression, and viral infections, including COVID-19. In this context, in-silico tools capable of accurately predicting...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
to Adjuvant strategies to tackle mcr-mediated polymyxin resistance By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00654B, Review ArticleMadison R. Nuske, Junlang Zhong, Renjie Huang, Vijayalekshmi Sarojini, Jack L. Y. Chen, Christopher J. Squire, Mark A. T. Blaskovich, Ivanhoe K. H. LeungThe emergence of the mobile colistin resistance (mcr) gene is a significant threat contributing to the worldwide antibiotic resistance crisis. This review discusses adjuvant strategies to restore polymyxin sensitivity in these resistant bacteria.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
to U.S. Presidential polls: Thulasendrapuram residents pray for Kamala Harris ‘victory By www.thehindu.com Published On :: Tue, 05 Nov 2024 12:48:36 +0530 Full Article U.S. Elections
to Changes in train services notified due to demolition of old bridge near Tiruchi junction By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:30:53 +0530 Full Article Tiruchirapalli
to Will decide on sharing stage with actor Vijay in consultation with VCK leaders: Thirumavalavan By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:44:09 +0530 Mr. Thirumavalavan told reporters in Tiruchi that the book release event was not something that was planned recently, and that he had consented to take part in it almost a year ago Full Article Tamil Nadu
to Frequent traffic snarls pose hardship to motorists in Tiruchi By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:45:36 +0530 It is common to see vehicles lining up for a long distance from the traffic signal near Cauvery bridge to Anna Statue. Full Article Tiruchirapalli
to Doctor assaulted inside Tiruchi ESI Hospital By www.thehindu.com Published On :: Tue, 05 Nov 2024 18:29:04 +0530 Full Article Tiruchirapalli
to 50 new primary health centres to be opened in State soon: Minister By www.thehindu.com Published On :: Tue, 05 Nov 2024 19:37:18 +0530 Full Article Tiruchirapalli
to Tiruchi Today (November 7, 2024) By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:16:44 +0530 Full Article Tiruchirapalli
to Duo arrested for possession of banned tobacco products worth ₹3 lakh in Tiruchi By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:23:30 +0530 Full Article Tiruchirapalli
to Agro-tourism push needs industry-specific policies, say farmers By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:37:41 +0530 Full Article Tiruchirapalli
to Three arrested for assaulting doctor in ESI hospital By www.thehindu.com Published On :: Wed, 06 Nov 2024 19:23:47 +0530 Full Article Tiruchirapalli
to Pumping stations to be set up in eight low-lying areas in Tiruchi to prevent inundation By www.thehindu.com Published On :: Wed, 06 Nov 2024 19:30:58 +0530 Full Article Tiruchirapalli
to Plea to include ‘panneer karumbu’ in Pongal gift hamper By www.thehindu.com Published On :: Wed, 06 Nov 2024 19:41:17 +0530 Full Article Tiruchirapalli
to Case filed against actor Kasthuri over remarks on Telugu community By www.thehindu.com Published On :: Wed, 06 Nov 2024 19:46:03 +0530 Full Article Tiruchirapalli
to HC directs authorities to maintain park and ensure no encroachment By www.thehindu.com Published On :: Wed, 06 Nov 2024 21:09:52 +0530 Full Article Madurai
to Property owners block the entrance to Balasubramanya temple in Karur By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:35:45 +0530 Full Article Tiruchirapalli
to Govt. urged to extend last date to pay crop insurance premium by farmers By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:45:02 +0530 Full Article Tiruchirapalli
to Udhayanidhi lays foundation stone for infrastructure development projects in Thanjavur district By www.thehindu.com Published On :: Thu, 07 Nov 2024 18:48:04 +0530 Buildings at the Government Arts and Science College, Thirukkattupalli, construction of compound wall and an indoor stadium at the Government Rajah Serfoji College, Thanjavur, are among the projects Full Article Tiruchirapalli
to Ernakulam Express to stop at Muthupettai during Kandhoori festival By www.thehindu.com Published On :: Thu, 07 Nov 2024 18:51:18 +0530 Full Article Tiruchirapalli
to Tiruchi Corporation embarks on special drive at night to capture and sterilise street dogs By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:10:58 +0530 About 125 stray dogs have been caught and sterilised at Tiruchi animal birth control centres in the last 10 days after the Corporation launched the special drive Full Article Tiruchirapalli
to HR&CE plans to bring properties around the Vennaimalai Temple under tenants list By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:36:32 +0530 The HR&CE department has cleared 34 properties around the Balasubramanyaswamy Temple at Vennaimalai in Karur district as per the High Court orders Full Article Tiruchirapalli
to Tiruchi district SHGs compete to prepare healthy millet-based recipes at food festival By www.thehindu.com Published On :: Fri, 08 Nov 2024 07:51:25 +0530 Women entrepreneurs urged to take advantage of social media platforms to advertise and market their products to a wider customer base Full Article Tiruchirapalli
to Consultant to be appointed soon to design Kalaignar grand library in Tiruchi By www.thehindu.com Published On :: Fri, 08 Nov 2024 18:41:18 +0530 The centre will offer translation, services for persons with disabilities and children, training and mentorship programmes, besides hosting monthly literary events Full Article Tiruchirapalli
to High-level committee formed to facilitate clearances for companies that signed MoU, says Minister By www.thehindu.com Published On :: Fri, 08 Nov 2024 18:56:40 +0530 Constant monitoring was being done now from the time of signing of MoUs to providing employment in new industrial units, says Industries Minister T.R.B. Rajaa Full Article Tiruchirapalli
to Fishermen seek healthcare and cold storage facilities By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:03:17 +0530 Full Article Tiruchirapalli
to NTK chief Seeman booked for alleged ‘derogatory remarks’ against Karunanidhi By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:03:53 +0530 Full Article Tiruchirapalli
to Small-scale handloom park to come up at Sengunthapuram By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:09:38 +0530 Ministers R. Gandhi and S.S. Sivashankar inspect the 13,205 sq. ft. site belonging to the Tamil Nadu Cotton Corporation at Sengunthapuram Full Article Tiruchirapalli
to Uppiliyapuram, gateway to scenic Pachamalai, lacks bus stand with passengers left to fight the elements By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:20:03 +0530 Buses stop at a busy junction making it difficult for commuters as well as local businessmen; a site is yet to be identified for the bus stand Full Article Tiruchirapalli
to Two doctors posted at Uppiliyapuram UPHC By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:29:46 +0530 Full Article Tiruchirapalli
to Library to hold Group II-A Mains, Group IV TNPSC model test By www.thehindu.com Published On :: Sat, 09 Nov 2024 17:59:22 +0530 Full Article Tiruchirapalli
to Man attempts to end life, kills his wife and daughter By www.thehindu.com Published On :: Sat, 09 Nov 2024 18:03:18 +0530 Full Article Tiruchirapalli
to AIADMK ready to join hands with like-minded parties to defeat DMK: Palaniswami By www.thehindu.com Published On :: Mon, 11 Nov 2024 00:39:42 +0530 Full Article Tiruchirapalli
to 542: Breaking Up with CSS-in-JS, Mastodon, and Stories on the Web By shoptalkshow.com Published On :: Mon, 21 Nov 2022 08:00:51 +0000 We're talking CSS-in-JS, Token CSS, Matuzo being suspended from Twitter, trying out Mastodon, testing out stable diffusion, stories on the web, and Jake Albaugh's new social network. Full Article All Episodes CSS mastodon stories Twitter
to 543: Zach Leatherman on Eleventy, Mastodon, Twitter, and is-land By shoptalkshow.com Published On :: Tue, 29 Nov 2022 16:30:32 +0000 Zach Leatherman talks with us about what's new with Eleventy, setting up on Mastodon, what's happened with Twitter, and is-land. Full Article All Episodes eleventy mastodon Twitter Web Components
to 552: Do You Want to Build a JS Framework? ☃️ CSS Wishlist for 2023 By shoptalkshow.com Published On :: Mon, 13 Feb 2023 10:07:40 +0000 Austin power updates, what do you need if you want to build a new JavaScript framework, and what do we hope CSS brings in 2023? Full Article All Episodes color CSS Javascript
to 565: The Hurdy-Gurdy, OKLCH, Edge Dev Tools, and Ad Blocking By shoptalkshow.com Published On :: Mon, 15 May 2023 08:20:15 +0000 Dave doesn't hate the hurdy-gurdy, but it's creation is an interesting parallel to software development. OKLCH follow up, @media, Edge drops new dev tools, CSS and Astro theming, JavaScript devs discover PHP, how many people block ads, and accessibility and grids. Full Article All Episodes Accessibility edge oklch
to 568: Display Contents, Passkeys Follow Up, Yellow Fade Technique, and TOTK Talk By shoptalkshow.com Published On :: Mon, 05 Jun 2023 19:53:09 +0000 Macho Man Randy Standards stops by for a quick chat, Passkeys follow up, discussing the safety of Display: contents, the yellow fade technique, how hot CSS is right now (so hot), and a check in on how everyone's doing with Tears of the Kingdom. Full Article All Episodes Astro botw passkeys totk yellow fade
to 571: Searching vs AI, Getting Designers to Play Nice, and Web Components By shoptalkshow.com Published On :: Mon, 26 Jun 2023 09:00:02 +0000 Do you listen at 2x? Do Chris and Dave sound weird at normal speed IRL? How searching compares to using AI, chatbots kind of suck at context, getting a designer to work with developers at an agency, what happened to content visibility, and how to best build a design system using web components. Full Article All Episodes AI chatgpt Web Components
to 578: Customer Support, P3 Color, Dave on Productivity, and Mobile vs Desktop By shoptalkshow.com Published On :: Mon, 14 Aug 2023 07:24:25 +0000 Is Apple's Numbers amazing or the worst? Customer support at various levels of software, Figma and P3 color, imagining a colorspace property in CSS, what's Dave doing for productivity, how has offloading CSS Tricks affected Chris, and should we build different websites for mobile vs desktop? Full Article All Episodes css tricks p3 Productivity Tools
to 583: Language Models, AI, and Digital Gardens with Maggie Appleton By shoptalkshow.com Published On :: Mon, 18 Sep 2023 08:20:09 +0000 Maggie Appleton talks with us about her work at Elicit, working with large and small language models, how humans vet the responses from AI, the discussion around the Soggoth meme in AI, using Discord as UI, what to do if your boss wants AI in your app, and why does she call her blog a digital garden? Full Article All Episodes AI Design digital garden
to 586: Micro.blogging with Manton Reece By shoptalkshow.com Published On :: Mon, 09 Oct 2023 10:00:38 +0000 Manton Reece, creator of Micro.blog, stops by to talk about the history of Micro.blog, what it's written in, how it handles feeds coming in and going out, cross-posting, authentication, and the somewhat hidden features of Micro.blog: bookmarking, bookshelves, and even podcasting. Full Article All Episodes Blogging micro.blog microblogging
to 594: Wiping Your Laptop, UX of Password Codes, and :Has Tips and Tricks By shoptalkshow.com Published On :: Mon, 04 Dec 2023 09:15:20 +0000 In this episode we're discussing making tech videos, website tinkering, :has tricks, SVG path commands, and the complexities of CSS & JavaScript logic. Full Article All Episodes bookshelf screencast shorts SVG tiktok
to 597: How Many VS Code Plugins, Poor Charlie’s Almanack, and Where to Start in 2024? By shoptalkshow.com Published On :: Mon, 08 Jan 2024 10:06:30 +0000 We're closing in on episode 600 and need your help to celebrate! Listen in to learn how to contribute to the episode. We're also talking GitHub desktop apps and code editors, how many VS Code plugins are needed, reading long form like Poor Charlie's Almanack, InVision shutting down, and answering our first Q of the year: how would you approach learning web development in 2024? Full Article All Episodes Education episode 600 Github vs code
to 620: Cloudflare #HotDrama, Auth, and Prototyping Thoughts By shoptalkshow.com Published On :: Mon, 17 Jun 2024 08:27:24 +0000 Show DescriptionWe dive a bit deeper into the Cloudflare drama of the past couple of weeks, Instagram ads vs Cara art, what to do about Auth in your app, pre-negging any sponsorships, prototyping and feedback on projects, and ideas for future topics. Listen on Website →Links Cloudflare took down our website after trying to force […] Full Article All Episodes Cloudflare Prototyping Web Components
to 628: Tending to RSS Feeds, Code Hike’s Fine Markdown, and Cloudflare R2 By shoptalkshow.com Published On :: Mon, 12 Aug 2024 07:04:48 +0000 Doc told me to travel but there's COVID on the planes, Dave's got a 2x life update, how often do you manage or prune your RSS feed subscriptions, checking in on Code Hike and their fine grained Markdown approach, JavaScript decorators use case, and using Cloudflare R2 for image storage. Full Article All Episodes Cloudflare covid-19 dogs markdown R2 rss
to How to save power By www.thehindu.com Published On :: Fri, 20 Feb 2015 19:25:41 +0530 U. V. Krishna Mohan Rao tells Hema Vijay how families waste electricity Full Article Green Living
to Grey to gold By www.thehindu.com Published On :: Fri, 20 Feb 2015 19:51:11 +0530 Use a three-compartment overhead tank to treat greywater. Full Article Green Living
to Design to beat the heat By www.thehindu.com Published On :: Sun, 03 May 2015 20:42:58 +0530 Keeping the air conditioner on for long will only create heat islands, says Sathya Prakash Varanashi Full Article Design