Analysis of taste sensory responses has been a powerful approach for understanding principles of taste detection and coding. The shared architecture of external taste sensing units, called sensilla, in insects opened up the study of tastant-evoked responses in any model of choice using a single-sensillum tip recording method that was developed in the mid-1900s. Early studies in blowflies were instrumental for identifying distinct taste neurons based on their responses to specific categories of chemicals. Broader system-wide analyses of whole organs have since been performed in the genetic model insect Drosophila melanogaster, revealing principles of stereotypical organization and function that appear to be evolutionarily conserved. Although limited in scope, investigations of taste sensory responses in mosquitoes showcase conservation in sensillar organization, as well as in groupings of functionally distinct taste neurons in each sensillum. The field is now poised for more thorough dissections of mosquito taste function, which should be of immense value in understanding close-range chemosensory interactions of mosquitoes with their hosts and environment. Here, we provide an introduction to the basic structure of a taste sensillum and functional analysis of the chemosensory neurons within it.

Transposon-mediated transgenesis of mosquito vectors of disease pathogens followed the early success of transgenesis in the vinegar fly, Drosophila melanogaster. The P transposable element used in Drosophila does not function canonically in mosquitoes, and repeatable, routine transgenesis in mosquitoes was not accomplished until new transposable elements were discovered and validated. A number of distinct transposons were subsequently identified that mediate the introduction of exogenous DNA in a stable and heritable manner in mosquito species, including members of the genera Aedes, Anopheles, and Culex. The most versatile element, piggyBac, is functional in all of these mosquito genera, as well as in many other insects in diverse orders, and has been used extensively outside the class. Transposon-mediated transgenesis of recessive and dominant marker genes and reporter systems has been used to define functional fragments of gene control sequences, introduce exogenous DNA encoding products beneficial to medical interests, and act as "enhancer traps" to identify endogenous genes with specific expression characteristics.

Volker (OM Montenegro) describes how their outdoor lessons for Roma kids were threatened by bad weather. Then God provided not only the solution - building a carport as a shelter - but also the funds and manpower needed to build it.

Local people notice the unity in Christ of OM Montenegro as the team work and relax together.

The OM team in Bar, Montenegro, received an enthusiastic response when they showed the JESUS film in the Roma language for the first time.

Every other week the OM team in Bar visits a Roma community to teach the children to read and write.

God transforms the hearts of teens from two people groups, who normally do not interact, to bring them together for worship, Bible study and friendship.

Can young people be united in faith, irrespective of their ethnic background? The answer is yes!

Even if things don't go quite to plan, the kids' craft sessions at OM Montenegro's Lighthouse centre result in wonderful presents for families.

After making friends at OM's English Cafe, Igor shares with them how he came from a similar background but was freed from despair when he met Jesus.

Pioneering Technology Allows Surgeons to Cut Precisely and Control Bleeding Without Causing Heat Damage to Tissue

Centuries-old university standardizes on SolidWorks Education Edition software so students can learn CAD and design validation skills

Knee replacement doesn’t have to be ‘total’

Quadruped Dinosaur Stomps the Rest of the Competition

Flagship Data Management Solution Introduces‘Item-Centric’ PDM and New BOM Functionality

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Quick design turnaround and easy documentation process help UK-based company move products to market faster

Switch to SolidWorks 3D CAD and Simulation Software Delivers Productivity Increase over AutoCAD

Sir Richard Branson, Jeff Ray, Jon Hirschtick, and World-Class Companies to Shine at World’s Largest Annual SolidWorks Gathering

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Eliminates the Cost and Complexity of Maintaining Online Parts Catalogs; Improves Search, Navigation, and Communication for Engineers Seeking 3D Part Models

Solutions Catch Problems Early and Drive Cost Out of Designs

Vault Structures Saves $150,000 in Prototyping Costs, Cuts Development Time by 70 Percent Using SolidWorks Software

New Licensing, Support Programs For Certification Accompany Software Upgrades

Leading elevator components supplier implements 550 licenses of the SolidWorks PDM solution

One Of Only Four Companies To Place Among Top Employers In Each Year Of The Publication’s Survey

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3D CAD Software’s Superior Data Translation Capabilities Support Growth of Tech Publishing and Engineering Services

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Non-Profit Cooperative Assembled Virtual Team to Prove $1,000 Incubator Was Possible, Safe, and Reliable

Engineers Use 3D CAD and Simulation To Customize Products With Quick Modifications, Testing, and Demonstrations

367.382 mph in a Two-Wheeled Missile

Curventa and RuRoc Adapt Original Design for Formula One Pit Crew Safety Wear

CAD and Documentation Solutions Enable U.K.-Based Company To Create Bath Fixtures For Safe, Easy Access

Sharing Information Between Design and Production Eliminates Budget Overruns That Erode Customers’ Profits

World Cup Champion Noelle Pikus-Pace Turns To Local Metal Shop – And Her Husband – For Innovative New Sled

Austrian Ski Manufacturer Reduces Development Time by 50 Percent with SolidWorks CAD and Simulation Software

ioSafe Uses SolidWorks to Design Disaster-Proof Computer Hardware; Company Saves $15,000 and Three Months