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Mediated electron transfer in a photo-bioreactor: continuous flow hydroxylation using cytochrome P450 BM3 in NADPH-free conditions

React. Chem. Eng., 2024, 9,803-815
DOI: 10.1039/D3RE00569K, Paper
Ali Fendri, Donya Valikhani, Joelle N. Pelletier
We designed a proof-of-concept photo-bioreactor enabling continuous flow NADPH-free activation of cytochrome P450 BM3 via mediated electron transfer.
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Synthesis of hollow sphere structured TiO2 loaded with Ag2O and its photocatalytic activity

React. Chem. Eng., 2024, 9,861-871
DOI: 10.1039/D3RE00473B, Paper
Hejin Liu, Ying Liu, Xueqin Wang, Peng Qiao, Wenyi Wang, Mei Zhang, Yanxiu Liu, Hua Song
Owing to its high stability and catalytic activity, TiO2 has been widely used as a photocatalyst where its photocatalytic performance can be significantly improved by microstructure regulation and semiconductor loading.
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A robust data analytical method to investigate sequence dependence in flow-based peptide synthesis

React. Chem. Eng., 2024, 9,825-832
DOI: 10.1039/D3RE00494E, Paper
Open Access
Bálint Tamás, Pietro Luigi Willi, Héloïse Bürgisser, Nina Hartrampf
A new data analytical method for flow-based peptide synthesis enables robust and quantitative analysis of sequence-dependent difficult couplings.
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The electrochemical oxidation of a thioether to form an API intermediate and the effects of substrate electronics on impurity formation

React. Chem. Eng., 2024, 9,883-887
DOI: 10.1039/D3RE00632H, Paper
Hamish R. Stephen, Holly Longhurst, Michael Nunn, Christopher D. Parsons, Matthew Burns
Electrochemistry was explored as a means of oxidising a thioether to form a sulfone API intermediate.
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Encapsulation of TixFeyLamOz nanoparticles into NH2-MIL-125(Ti) to fabricate a promising photocatalyst for the C–N coupling reaction

React. Chem. Eng., 2024, 9,849-860
DOI: 10.1039/D3RE00457K, Paper
Yahya Absalan, Mohammad Rafsanjani Dehghazi, Reza Samavati, Kambiz Souri, Mostafa Gholizadeh
An array of organic compounds and natural products can be synthesized through carbon–nitrogen coupling reactions.
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Machine-learning assisted optimisation during heterogeneous photocatalytic degradation utilising a static mixer under continuous flow

React. Chem. Eng., 2024, 9,872-882
DOI: 10.1039/D3RE00570D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Thomas M. Kohl, Yan Zuo, Benjamin W. Muir, Christian H. Hornung, Anastasios Polyzos, Yutong Zhu, Xingdong Wang, David L. J. Alexander
Machine-learning assisted optimisation of a continuous photodegradation reaction, using a TiO2 coated catalytic static mixer successfully accounting for catalyst degradation.
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From microkinetic model to process: understanding the role of the boron nitride surface and gas phase chemistry in the oxidative dehydrogenation of propane

React. Chem. Eng., 2024, 9,795-802
DOI: 10.1039/D3RE00600J, Paper
Unni Kurumbail, William P. McDermott, Edgard A. Lebrón-Rodríguez, Ive Hermans
In the oxidative dehydrogenation of propane over boron nitride, propylene selectivity is lost due to unselective gas-phase chemistry.
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At-line monitoring of hydrogen peroxide released from its photocatalytic and continuous synthesis

React. Chem. Eng., 2024, 9,777-781
DOI: 10.1039/D3RE00659J, Communication
Open Access
Anders Ø. Tjell, Lars-Erik Meyer, Barbara Jud, Selin Kara, Torsten Mayr
Photocatalytic synthesis of H2O2 in a continuous operation set-up using nitrogen-doped carbon nanodots (N-CNDs) and simultaneous determination of generated H2O2.
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Digital Pareto-front mapping of homogeneous catalytic reactions

React. Chem. Eng., 2024, 9,787-794
DOI: 10.1039/D3RE00673E, Communication
Open Access
Negin Orouji, Jeffrey A. Bennett, Sina Sadeghi, Milad Abolhasani
We present a digital framework for rapid multi-objective reaction space exploration and optimization of homogeneous catalytic reactions through autonomous experimentation and Bayesian optimization.
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Merging inline crystallization and pulsed flow operation to enable enantiospecific solid state photodecarbonylation

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00058G, Paper
Open Access
Bavo Vandekerckhove, Bart Ruttens, Bert Metten, Christian V. Stevens, Thomas S. A. Heugebaert
Photoelimination of α-chiral ketones in the solid state results in highly regio- and enantiospecific C–C bond formation. By combining inline crystallisation and pulsatile flow, the photochemistry of these slurries can now be run fully continuously.
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Selective hydrogenation of 5-hydroxymethylfurfural to 2,5-bis(hydroxymethyl)furan over Ni–Ga intermetallic catalysts and its kinetic studies

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00129J, Paper
Weixiao Sun, Fuzeyu Zhong, Xiaohu Ge, Wenyao Chen, Gang Qian, Yueqiang Cao, Xuezhi Duan, Xinggui Zhou, Jing Zhang
5-Hydroxymethylfurfural (HMF) has been listed as the “TOP 14” most important biomass-derived platform molecules, which can be converted into 2,5-bis(hydroxymethyl)furan (BHF) via selective hydrogenation of the carbonyl group on HMF.
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Catalytic degradation of pine sawdust over heterotopic Ca–Fe and HZSM-5 to produce aromatic hydrocarbons

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D3RE00572K, Paper
Huifen Kang, Xintong Guo, Mei An, Conghua Ma, Guozhang Chang, Qingjie Guo, Jingjing Ma
Up to 90.47% aromatic proportion and a 31.02 mg g−1 BTEX yield were obtained by heterogeneous catalysis of Ca–Fe and HZSM-5.
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Efficient aqueous-phase hydrogenation of m-xylylenediamine to 1,3-cyclohexandimethylamine over a highly active and stable ruthenium catalyst

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D3RE00712J, Paper
Jing Guo, Heng Shao, Le Gao, Wancheng Ma, Wei Zhang, Long Huang, Haibin Chu
The strong interaction between Ru and –NH2 in Ru/NH2–Al2O3 led to the formation of highly dispersed Ru and modification of its electronic properties, and consequently greatly enhanced its performance and stability.
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Automated kinetic model identification via cloud services using model-based design of experiments

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00047A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Emmanuel Agunloye, Panagiotis Petsagkourakis, Muhammad Yusuf, Ricardo Labes, Thomas Chamberlain, Frans L. Muller, Richard A. Bourne, Federico Galvanin
Industry 4.0 has birthed a new era for the chemical manufacturing sector, transforming reactor design and integrating digital twin into process control.
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Enhancing mass transport to accelerate photoreactions and enable scale-up

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D3RE00689A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Florian Gaulhofer, Markus Metzger, Alexander Peschl, Dirk Ziegenbalg
The importance of mixing in photoreactors along the direction of light propagation for competitive photochemical reactions is experimentally demonstrated in the MISCOP mini-plant photoreactor.
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Photochemical organocatalytic heteroarylation of anilines and secondary alicyclic amines in continuous-flow

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00130C, Paper
Egor N. Boronin, Milena M. Svetlakova, Ilya I. Vorobyov, Yulia B. Malysheva, Yuri V. Polushtaytsev, Sergey N. Mensov, Andrey V. Vorotyntsev, Alexey Yu. Fedorov, Timothy Noël, Alexander V. Nyuchev
Photoorganocatalytic arylation of amines in continuous-flow enables scaling up including decreasing of both reaction time and catalyst loading.
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On a seamlessly replicable circular photoreactor for lab-scale continuous flow applications

React. Chem. Eng., 2024, Accepted Manuscript
DOI: 10.1039/D4RE00109E, Paper
Yi-Hsuan Tsai, Martin Cattoen, Guillaume Masson, Gabrielle Christen, Lisa Traber, Morgan Donnard, Frederic R. Leroux, Guillaume Bentzinger, Sylvain Guizzetti, Jean-Christophe M. Monbaliu
A cost effective and replicable continuous flow circular photoreactor system is introduced. All body parts of the reactor are 3D-printed and the electronics are purchased from various mainstream suppliers. The...
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A sequential lumped kinetic modelling approach for the co-pyrolysis of plastic mixtures with a heavy refinery intermediate product in a tubular reactor

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00075G, Paper
Open Access
Sebastian-Mark Lorbach, Andreas E. Lechleitner, Teresa Schubert, Markus Lehner
A novel sequential approach for the lumped kinetic modelling of a plastic pyrolysis process in a tubular reactor.
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Correction: Applying quantum mechanics to deconvolute benchtop 1H NMR reaction data

React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE90015D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jiayu Zhang, Tristan Maschmeyer, Ben Shapiro, Sunil Babu Paudel, Matthew C. Leclerc, Jason E. Hein
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Synthesis and kinetic study of 1,3,2-dioxathiolane 2,2-dioxide in microreactors

React. Chem. Eng., 2024, Accepted Manuscript
DOI: 10.1039/D4RE00123K, Paper
Ting Wang, Junnan Wang, Chengxiang He, Zhongdong Wang, Yating Li, Chunying Zhu, Youguang Ma, Taotao Fu
1,3,2-dioxathiolane 2,2-dioxide (DTD) is an essential intermediate in organic synthesis and plays a vital role in improving the performance and service life of lithium-ion batteries. A large amount of heat...
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Bridgestone invests $85 million to boost premium tire production and development in India

Investment to focus on Bridgestone’s Pune and Indore manufacturing plants, with production capacity at the Pune plant set to increase by 1.1 million tires annually by 2029




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Shoppers Stop aims to scale up beauty distribution, bring more international brands to India

Shoppers Stop expects Global SS Beauty to end this fiscal with revenues to the tune of ₹220-250 crore




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Inteva Products to expand manufacturing facility in Pune with $3.3 million investment

Inteva Products’ expansion project to increase the plant’s production space by 70 per cent, to a total of 85,000 square feet




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Ola Electric sees 5% y-o-y loss reduction to ₹495 crore for Q2FY25

Revenue for the quarter under review increased by 38.5 per cent y-o-y to ₹1,240 crore from ₹896 crore in the year-ago period




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Tata Motors’ Q2 profit falls 11.18% due to weak performance

Lower sales volumes, supply constraints and underperformance of JLR, PVs resulted in the decline in profits




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Lupin aims to be part of ‘first wave of generics’ on GLP-1 products: Nilesh Gupta

GLP-1 products going off patent in some markets includes popular Type-2 diabetes and weight-loss drug Ozempic




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Ashok Leyland expands to Southeast Asia, expects domestic market recovery in H2

EV Arm Switch Mobility set for EBITDA break-even this fiscal




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Coca-Cola set to launch Vitaminwater in India

Company’s focus on premium hydration portfolio with an expected quick commerce first launch in top cities.




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Pantomath’s Bharat Value Fund invests ₹235 cr in Haldiram Bhujiawala

The company will use the funds to expand its manufacturing and markets outside East and North-East India




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Enphase Energy to cut workforce by 17%; to focus manufacturing in the US, India and China

500 employees and contractors to be affected by the lay-offs




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UnifyApps raises $20 million in Series A funding to deliver AI agents across enterprise

Iconiq Growth has invested in companies like Airbnb, Uber and Snowflake. ICONIQ Growth General Partner Matt Jacobson has joined UnifyApps’ board of directors as part of the new funding




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PFC turns down $2.4 billion debt to Shapoorji

With the latest move, the company may have to find new ways to raise money




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India’s steel exports rise 11% in October; imports moderate for the first time this fiscal

Indian steel exports rose to 0.44 million tonnes in October, while imports moderated for the first time this year to 0.98 million tonnes as India tightened import norms




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Asian Paints profit declines 43.7% to ₹693.7 crore in Q2

Asian Paints had logged a net profit of ₹1,232.39 crore during the July-September period a year ago




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Singapore Airlines to invest additional ₹3,195 crore in Air India post-Vistara merger

The merger will result in Singapore Airlines having a 25.1% stake in the enlarged Air India




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Zomato launches Food Rescue initiative to prevent wastage due to cancellations

The platform said that every month, about four lakh food orders are cancelled, posing a serious challenge




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Industrial AI firm Avathon to focus on India for R&D growth, aims to triple workforce in two years

India will play a pivotal role in our expansion, serving as a hub for product engineering, delivery, support and R&D, says CEO Johan




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KFC, Pizza Hut operator Devyani International posts net loss of ₹4.92 crore, revenues up 49%

The company also announced that it has secured Exclusive Master Franchise rights for three new QSR brands which include TeaLive, New York Fries and Sanook Kitchen




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India’s gaming industry soars to $3.8 billion, set to reach $9.2 billion by FY29: Report

The report, developed in collaboration with Google and Deloitte, shows that India is the world’s second-largest mobile gaming market, recording 15.2 billion downloads




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ITC’s snack brand Bingo! Inks five-year partnership to promote Pickleball in India

This partnership, starts with the Bingo! World Pickleball Championship (WPC)




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LB Brewers partners with Taiwanese company to launch bottled tea beer

LB Brewers also entered the craft rice lager segment with MAKA di Rocket Rice Lager, consumed across Goa, Uttar Pradesh, US, Canada, and UAE




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ZEISS India expands its GCC, plans to double workforce by 2028

The company currently employs 2,500 people across various functions




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Domestic tractor sales hit historic high in festive October, H2 outlook remains robust

Total tractor sales in the domestic market grew by 23%per cent to 144,675 units in October 2024




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Ramco Cements raises ₹376 cr via sale of non-core assets, repays ₹326 cr debt in October

Q2 net profit declines 74 per cent % year-on-year due to drop in prices




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20% of company’s R&D headcount based in India, GoTo CEO says

IT management company GoTo has around 20 per cent of its R&D headcount in India, said company CEO Rich Veldran




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Muted demand dents Britannia Industries consolidated Q2 PAT to ₹531 crore

Revenue from operations reached ₹4,667.57 crore in the second quarter (₹4,432.88 crore), up 5.29 per cent




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Exide Industries realigning B2B and B2C to strengthen go to market strategy

The leadership hiring move is a part of the company’s growth agenda to strengthen its business-to-consumer (B2C) and business-to-business (B2B)




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L&T Technology Services to acquire Silicon Valley-based Intelliswift

LTTS claims the acquisition will deepen its offerings across software product development, platform engineering, digital integration, data, and AI




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Other income takes TVS SCS into profits

Improved business environment attributed to the turnaround




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Wheelocity secures $15 million to transform e-commerce in semi-urban India 

Originally a B2B platform, Wheelocity has transitioned to a B2C model, now serving over 1 million households across 3,500 towns and villages