Provided is a pneumatic tire whose braking performance on ice and partial-wear resistance can be improved. Sipes 11X provided in a rib 5 on a tire equatorial plane TE are formed in such a three-dimensional shape that the amount at which the rib 5 collapses due to an external force is smaller in the tire rotational direction than in a direction opposite to the tire rotational direction. In each block 10 in each shoulder region 1S, sipes 11Ma in a block tread-in side portion 10A are each formed in such a three-dimensional shape that the amount at which the block 10, if entirely provided with the sipes 11Ma, collapses due to an external force will be smaller in the tire rotational direction than in the direction opposite to the tire rotational direction. Sipes 11Mb in a block kick-out side portion 10B are each formed in such a three-dimensional shape that the amount at which the block 10, if entirely provided with the sipes 11Mb, collapses due to an external force will be smaller in the direction opposite to the tire rotational direction than in the tire rotational direction.

A heavy duty pneumatic tire comprises a tread portion provided with circumferentially continuous main grooves and lateral grooves to form blocks in circumferential rows. The main grooves include a pair of shoulder main grooves disposed one on each side of the tire equator so that the center line thereof is at a distance of 0.30 to 0.65 times one half of the tread width from the tire equator. The blocks include crown blocks disposed in a tread crown region between the shoulder main grooves, and shoulder blocks disposed in shoulder regions axially outside the shoulder main grooves. Each of the crown blocks and shoulder blocks is provided with at least one axially extending sipe.

An object of the present invention is to provide a pneumatic tire of which rolling resistance is reduced without impairing wear resistance. Specifically, the pneumatic tire of the present invention comprises: a tread portion; a pair of side wall portions; a pair of bead portions; a carcass constituted of at least one carcass ply extending in a toroidal shape between bead cores in the respective bead portions; a belt disposed on the outer peripheral side of a crown region of the carcass and formed by at least one inclined belt layer made of cords extending to be inclined with respect to the equatorial plane of the tire; and a tread rubber disposed on the radially outer side of the belt, wherein a ratio of BD/BW satisfies the following formula: (0.062×tire aspect ratio−0.01)

In the invention, at least a tire outer circumferential side portion of a tread portion is formed of a non-conductive rubber layer. The non-conductive rubber layer is formed by winding and laminating a non-conductive rubber ribbon along a tire circumferential direction. A conductive layer is provided on an outer circumference of the non-conductive rubber ribbon, and the conductive layer continuously and spirally extends along the tire circumferential direction, and is exposed on a tread surface from a bottom surface of the non-conductive rubber layer toward a tire outer circumferential side. Accordingly, an electricity generated in a vehicle body is discharged to a road through the conductive layer. Since the conductive layer is scattered within the non-conductive rubber layer and exposure on the tread surface is preferably secured, it is possible to achieve an excellent conductivity.

A pneumatic tire in which: a carcass layer is laid between paired bead sections; a belt layer is buried, on the outer peripheral side of the carcass layer, in a tread section; and multiple main grooves extending in a tire circumferential direction are provided in the tread section. In the pneumatic tire, a maximum groove depth of each of the main grooves is 8.5 mm to 15.0 mm, a ratio α of a section height SH of an actual tire to a section height SHstd calculated from a tire size is set in a range of 0.97≦α≦0.99, a contact area ratio is 65% to 70% under a measurement condition where an air pressure is 200 kPa and a load is 50% of a load carrying ability with the air pressure of 200 kPa, and an average contact pressure P is 300 kPa to 400 kPa under the measurement condition. The tire achieves enhanced wet performance without increasing tire weight.

A rubber-steel hybrid cord of the present invention is characteristically formed by twisting a plurality of sheath filaments or sheath strands around a core in which a periphery of and space surrounded by one or a plurality of core filaments or a core strand are coated or filled with a filler rubber (A) containing an adhesion promoter, thereby forming a multilayer-twist steel cord or a multi-twist steel cord, and coating an outer surface of the multilayer-twist steel cord or the multi-twist steel cord with a coating rubber (C). Further, an amount of an adhesion promoter contained in the coating rubber (C) is equal to or more than an amount of the adhesion promoter contained in the filler rubber (A).

Provided is a pneumatic tire whose safety factor and durability are improved without generating a problem of an increase in the weight of a tire and an increase in the inner surface cord protrusion failure. Provided is a pneumatic tire including one or more carcasses 2 extending toroidally between bead cores 1 embedded in a pair of bead portions 11 respectively. A polyester fiber cord whose total decitex as a twisted cord is 4300 to 5100 dtex, whose cord strength as a dip treated cord is 6.5 to 7.2 cN/dtex and whose cord elongation at a stress loading of 2 cN/dtex is 3.5 to 4.0% is used as a reinforcing cord of the carcass 2, and the tenacity of a treat which is the reinforcing cord covered with rubber per unit width is 2.9 to 3.2 kN/cm.

A pneumatic tire for a commercial vehicle with a tread, wherein at least the part of the tread which comes into contact with the road contains a sulphur-vulcanized rubber mixture. The sulphur-vulcanized rubber mixture contains 90 to 50 phr (parts by weight, based on 100 parts by weight, of all of the rubbers in the mixture) of natural rubber, 10 to 50 phr of at least one polybutadiene having a glass transition temperature Tg of −110 to −65° C. and 5 to 50 phr of at least one aliphatic and/or aromatic hydrocarbon resin having a softening point (ring and ball to ASTM E 28) of 0 to 150° C., and a mean molecular weight Mn of less than 2000 g/mol and a polydispersity D=Mw/Mn of 1 to 5.

A pneumatic tire includes first and second side members at first and second sides and a tread section between the first and second side members. The tread section has a tread pattern including a pair of main grooves extending linearly in a circumferential direction of the tire and a land section extending in the circumferential direction between the main grooves. The land section includes a sub groove extending in the circumferential direction without connecting to the main grooves, and a first sipe connecting between the sub groove and one of the main grooves. The sub groove includes a first groove section extending diagonally toward the first side at 0 to 30 degrees with respect to the circumferential direction and a second groove section connecting to the first groove section and extending diagonally toward the second side at 10 to 45 degrees with respect to the circumferential direction.

Side lug rows are provided at both side regions of a tread surface and are formed by a plurality of lugs defined by lug grooves opening to edges in the tread width direction, and a central block row aligned on the tire equator and formed by a plurality of blocks is disposed between positions at ¼ of the tread surface width from the tire equator. The tire has a directional tread pattern, with a designated rotation direction, formed by circumferential grooves and width direction grooves that define the blocks of the central block row and are narrow grooves with a narrower groove width than the lug grooves. The distance from the tire equator to the groove wall in each of the circumferential grooves defining the blocks is set to be larger at a leading edge of each block than at a trailing edge of each block.

The pneumatic tire 1 includes a belt layer 14 that includes a circumferential reinforcing layer 145 and a pair of cross belts 142, 143. Also, the pneumatic tire 1 includes at least three or more circumferential main grooves 21 to 23 in the tread portion having groove bottoms that are convex in the groove depth direction. Also, the curvature radius RA of the groove bottom of an arbitrary first circumferential main groove 21, 22 and the curvature radius RB of the groove bottom of an arbitrary second circumferential main groove 23 have the relationship RA

A pneumatic tire comprises a tread portion, at least two circumferentially and continuously extending longitudinal grooves being provided with the tread portion, a land portion divided between the longitudinal grooves, a plurality of lateral grooves being provided with the land portion, each lateral grooves with one end communicating with one of the longitudinal grooves and the other end extending toward a tire equator, the longitudinal groove with a groove wall to which lateral grooves are connected, in each section between lateral grooves adjacent to a circumferential direction of the tire, the groove wall having a protruded portion and a dent portion being formed the nearest side of the tire equator, the protruded portion inclined with respect to the circumferential direction of the tire so as to gradually reduce a width of the longitudinal groove toward at least one lateral groove.

A pneumatic tire unit comprises a front tire to be mounted on a leading side of a vehicle, and a rear tire to be mounted on a trailing side of the vehicle. A plurality of recesses is provided in at least one tire side portion of the front tire, and a plurality of protrusions is provided on at least one tire side portion of the rear tire. A negative pressure region that can be generated at a back surface side of the vehicle is reduced and, therefore, air resistance of the vehicle is reduced and fuel economy is enhanced.

A reuse support system of an embodiment includes a display controller which displays, on a display, an image including an image of a boundary sample which serves as a reference for reuse of a facility in response to operation of a worker, an acceptor which accepts selection of a reuse mode of the facility, and a manager which manages a delivery destination of the facility based at least in part on the reuse mode of the facility selected by the acceptor.

A reuse support system is provided. The system includes an acquisitor which acquires skill data of workers, a grantor which grants a work license to the workers based on the acquired skill data of the workers and stores the granted work license for each of the workers in a storage, and a provider which reads the work license from the storage in response to authentication operation of the workers and provides an image according to the read work license.

Methods and systems in accordance with the present invention allow users to efficiently manipulate, analyze, and transmit eXtensible Business Reporting Language (“XBRL”) reports. They allow users to automatically build financial reports that are acceptable to governing agencies such as the IRS. In one embodiment, the reports are developed by a parser that transforms text documents into software elements containing a format with a hierarchal relationship between the software elements, and an editor that develops reports by referencing the software elements transformed from the text documents. Methods and systems in accordance with the present invention also enable reports to be automatically scheduled by gathering desired information from an accounting system, formatting the information into an XBRL document, and transmitting it to an end source. Furthermore, systems and methods in accordance with the present invention allow a user to translate an XBRL document into RDL format and use the RDL system to manipulate and analyze it.

Disclosed is a system for detonating a buried explosive device by discharging an electric discharge with at least five joules of energy to detonate the buried explosive device.

Transient liquid phase sintering compositions comprising one or more high melting point metals and one or more low melting temperature alloys are known in the art as useful compositions for creating electrically and/or thermally conductive pathways in electronic applications. The present invention provides transient liquid phase sintering compositions that employ non-eutectic low melting temperature alloys for improved sintering and metal matrix properties.

A device for changing the rotational angle position of a pneumatic tire relative to a rim, on which the pneumatic tire is fitted to the rim, includes a manipulating device with a gripper adapted to be rotated by a positionable rotary drive mechanism and having radially adjustable gripper fingers with oppositely facing lift-off devices. Via the gripper it is possible to load a wheel into a clamping fixture, and following unseating of the tire beads from the clamped rim the pneumatic tire can be rotated relative to the rim through a computed angular difference.

There is described a machine (1) for regeneration of pneumatic tires (2) comprising a beading device (5) for axial locking of the pneumatic tire to be regenerated in the direction of the revolving axis of the pneumatic tire (2) which provides an untranslatable bead (6) and a translatable bead (7) in said direction, a work rasp (9) mounted on a spindle (25), inflation means (66) of the pneumatic tire and a discharge cochlea (77). Said machine further comprises a roughing miller (8) suitable to prepare the pneumatic tire to a subsequent finishing by means of the rasp (9), said miller (8) being mounted on the same spindle (25) of the rasp (9) and after it, and constituted of a monoblock (27) with discharge channels (28) for chips produced by inserts (29) with a curved profile (30) providing a plurality of planar blades (31) joined by discharge grooves (32) of the chips produced.

A reusable flexible sheet for wrapping an object is presented. The flexible sheet includes a center portion having a first side, a second side, a third side, and a fourth side, the first side being parallel to the third side and the second side being parallel to the fourth side. Flaps are connected to the first side and the third side, and bow portions are connected to the second side and the fourth side. The bow portions tie together to form a decorative bow.

A reusable gift wrap and a method of wrapping a gift comprising a sheet of material and a fastener. The sheet has a plurality of corners. The fastener comprises a body fabricated from a resilient material and is attached near one of the corners. A plurality of coterminous radially extending slits are formed in a face of the body and define the edges of a plurality of pivotable flaps and an opening for receiving the other corners of the sheet. The flaps comprises a living hinge which permit each of the flaps to pivot. The flaps increase in thickness from the living hinge to the edge of the flap. The three flaps simulate the appearance of a cuboidal gift box.

A method of produced water treatment in an in-situ recovery method of producing bitumen from oil sand, the method has the steps of: separating bitumen from bitumen-mixed fluid so as to leave produced water, the bitumen-mixed fluid having been recovered from the oil sand wells; and filtering the produced water via a microfiltration membrane made of polytetrafluoroethylene.

The present invention provides a method of converting coal to a petroleum product. The method includes the steps of mixing the coal and water to form a mixture, and heating the mixture to approximately 500 degrees Fahrenheit. The method further includes separating the mixture in a first separator into a liquid stream of a water bearing minerals and a solid stream of coal, and transferring the coal from the first separator to a coking reactor wherein the temperature is raised to approximately 1,000 degrees Fahrenheit to drive off lighter fractions of the coal as a gas. The method also includes transferring the gas to a fourth separator to separate water and liquid petroleum product from the gas.

This disclosure relates to combination therapies comprising anti-Pseudomonas Psl and PcrV bispecific binding molecules and related compositions, for use in prevention and treatment of Pseudomonas infection.

The invention relates to a human Interleukin-2 (hIL-2) specific monoclonal antibody (mAb), or antigen binding fragment thereof, the binding of which to hIL-2 inhibits binding of hIL-2 to CD25 and the antibody is characterized by any of the parameters: the variable chain of the mAb comprises the amino acid sequence of SEQ ID NO 005 or SEQ ID NO 006; the binding to hIL-2 is characterized by a dissociation constant (KD)≦7.5 nmol/L; the binding to hIL-2 is characterized by an off-rate (Koff)≦1×10−4 s−1 and/or the antibody displays no measurable cross-reactivity to murine IL-2.

The invention provides compositions and methods for treating leukemia, for example, acute myeloid leukemia (AML) and B-cell acute lymphoid leukemia (B-ALL). The invention also relates to at least one chimeric antigen receptor (CAR) specific to CD123, vectors comprising the same, and recombinant T cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD123 binding domain. The invention also includes methods of bone marrow ablation for use in treatments necessitating bone marrow reconditioning or transplant.

The present invention provides methods for assessing whether a subject is at risk of developing a neurological disorder, diagnosing or confirming whether a subject is afflicted with a neurological disorder, assessing whether PD has progressed in a subject afflicted with PD, assessing whether a neurological disorder is developing in a subject who has been identified as being at risk of developing the neurological disorder, assessing whether a subject afflicted with a neurological disorder is likely to benefit from a therapy, assessing whether a subject afflicted with a neurological disorder has benefited from a therapy, treating a subject afflicted with a neurological disorder, and prophylactically treating a subject who has been identified as being at risk of developing a neurological disorder. The present invention also provides epitopes, compounds and compositions relating to these methods.

To compete with the increasing global food demand, it is necessary to increase the food production. Fertilizers which are in practice now a days has major disadvantage that 50% of nutrient contents loss due to leaching and also leads to ground water contamination. Slow release nitrogenous fertilizers are good in this regard in that they have minimum nutrient loss due to leaching. Potassium aluminum silicate (Leucite) nanoparticles occluded by calcium ammonium nitrates are slow release fertilizers and are synthesized by hydrothermal method. Its application as slow released nitrates fertilizers was determined by observing nitrate release for 16 days.

A self-supporting, rigid, and collapsible reusable bag made from flexible material and having a bottom, two first sidewalls, two second sidewalls, a top opening, and rigid insert. A rigid full-wall board is embedded in each of the two first sidewalls. A rigid insert comprised of at least one pair of sidewalls and bottom with substantially similar dimensions to the second sidewalls and bottom of the bag are placed in the interior and in frictional contact with the second sidewalls and bottom of the bag. The rigid insert sidewalls are held in place with securing devices located on the interior upper corners of the sidewalls of the bag. The bag can be collapsed by moving the rigid insert away from the second sidewalls and bottom to allow the second sidewalls to fold either inward or outward. A full-wall pocket is provided for each first sidewall to receive the full-wall board.

A device and methods for bilateral or unilateral physical therapy of lower limbs are disclosed. The device comprises a curved rail mounted on a base and a pair of support members configured to accommodate a portion of a leg of a person, and to slide along the curved rail. The curved rail allows lateral movements of the lower limbs with the support members, the movements being driven by a force of the lower limbs. The methods of the invention allow physical unilateral or bilateral therapy of lower limbs of a person. The initial reinforcement of the lower limbs of a person is improved by the use of this device, which reduces the friction or the resistance caused by the device during the prescribed movements. The invention provides to patients with severe lower limb disability, a physical therapy device that is easy to use with minimum supervision by a physical therapist.

A insensitive explosive comprises: 34.9 wt % diethylenetriamine trinitrate (DETN),33.4 wt % ethylenediamine dinitrate (EDD),25.4 wt % methyl-guanidine (MeNQ), and6.3 wt % guanidine (NQ). This quaternary eutectic is used in combination with a sensitive explosive. A low melting temperature facilitates melt casting to fill 155 mm artillery shells.

Provided is a steel cord for reinforcing a rubber article, which has an improved durability against so-called cuts, such as notches and perforations, which are generated in the case of treading on an obtusely or sharply pointed projection, without decreasing the strength in the axial direction of the cord, and without increasing the thickness in the radial direction, namely without increasing the weight of a tire, as well as a tire using the steel cord for reinforcing a rubber article as a reinforcing material, especially a construction vehicle tire. Also provided is a steel cord for reinforcing rubber articles with a multi-twisted structure formed by twisting a plurality of sheath strands formed by twisting a plurality of wires around a core strand formed by twisting a plurality of wires, and the core strand being constituted of an at least three-layer-twisted structure formed by twisting core filaments and sheath filaments. The lowest tensile breaking strength of filament bs and the tensile breaking strength of steel cord Bc satisfy the relationship represented by the following formula: bs/Bc×100≧0.65.

A steel cord for reinforcement of rubber articles, whose cord strength is enhanced by preventing occurrence of preceding break of the outermost layer filaments in the steel cord having a multi-twisted structure, and a pneumatic tire using it as a reinforcing material are provided. In a steel cord for reinforcement of rubber articles having a multi-twisted structure in which a plurality of strands are twisted together, which strands have a layered twisted structure in which a plurality of steel filaments are twisted together, dc/ds, which represents the ratio between dc, the diameter of outermost layer sheath filaments constituting the outermost layer sheath of a core strand, and ds, the diameter of outermost layer sheath filaments constituting the outermost layer sheath of sheath strands, is 1.05 to 1.25.

Without decreasing the strength in the axial direction of the cord, and without increasing the thickness in the radial direction, a steel cord for reinforcing a rubber article, which improves durability against cut, as well as a construction vehicle tire utilizing the steel cord for reinforcing a rubber article as a reinforcing material is provided. A steel cord for reinforcing a rubber article is formed by twisting a plurality of sheath strands 2 formed by twisting a plurality of wires around a core strand 1 formed by twisting a plurality of wires, wherein the core strand 1 is constituted of a 4-layer-twisted structure and the diameter of the steel cord is 5 mm or larger. The tire of the present invention is a tire which has a belt constituted with 6 belt plies with cords arrayed on the outer side in the radial direction of the tire at a crown part of the carcass, which are crossed between the laminated plies, and wherein the steel cords for reinforcing a rubber article are applied to the third belt layer and the fourth belt layer.

An excavation system employing a high-pressure pulsed air jet that may optionally be used in combination with a low-pressure high velocity blower for excavating improvised explosive devices or other buried objects. The excavation system may also be employed to operate a pneumatic tool such as a cut-off tool or a chisel. The high velocity blower may incorporate a bifurcated fan duct having two air outlets. The system may include a pressure control module for regulating the from a high-pressure air source to an evacuation valve. The evacuation valve employs first and second valves where the second valve controls the operation of the first valve.

Methods, apparatuses, computer readable media for spatial reuse for uplink multi-user transmissions. An apparatus of a station comprising processing circuitry is disclosed. The processing circuitry may be configured to decode a first portion of a physical layer convergence procedure (PLCP) protocol data unit (PPDU), and configure the station to transmit a frame, if the PPDU is an overlapping basic service set (OBSS) PPDU, and a receive power of the PPDU is below an overlapping power detect level. An apparatus of an access point comprising processing circuitry is disclosed. The processing circuitry may be configured to encode a PPDU comprising a basic service set identifier of the access point, and encode the PPDU to indicate spatial reuse (SR) delay, SR restricted, or SR not permitted. The processing circuitry may be further configured to configure the access point to transmit the PPDU.

A vibration isolator with a pneumatic spring that is effective only in vertical direction, the pneumatic spring including a working space in which a vertically effective actuator is disposed.

A decelerator apparatus for mounting at the end of a pneumatic or gravity-fed fruit harvesting or delivery tube. The decelerator comprises a housing with a moving decelerator body aligned with a fruit-receiving inlet connected to the delivery tube. The decelerator body, for example a padded rotating wheel, moves at a speed slower than the speed at which the fruit is delivered into the housing, includes multiple depressions or indentations for receiving and separating fruit, and further defines a compressive deceleration path that moves the fruit in a compressive but protective fit toward a housing exit, releasing the fruit after the fruit has been decelerated to the speed of the moving body.

A reusable casket includes a metal casket box having an opening at one end and including a panel section rotatably attached to the casket box which is closeable to enclose the opening and openable to allow longitudinal movement of a casket insert into and out of the casket box through the opening. A transverse member adjacent the panel section connects opposing side panels of the box to partially define the opening. The panel section is retained to the transverse member in the closed position by locking bolts extending through the panel section to engage the transverse member. A method of making the metal casket box includes welding side, end, and floor panels together, moveably attaching the panel section relative to an opening in the end of the casket box, and attaching the transverse member to the side panels adjacent the panel section.

The present application provides a back mixing device for use with a pneumatically conveyed flow of solids having a varying flow rate. The back mixing device may include a nozzle, a chamber in communication with the nozzle, and an exit. The chamber may include an expanded area leading to a restriction such that the chamber creates a recirculation pattern in the flow of solids so as to smooth the varying flow rate though the back mixing device.

Mineral, cosmetic, pharmaceutical, agricultural, nutraceutical, and other compositions are produced using a mineral composition containing minimal concentrations of cadmium, lead, arsenic, and mercury and containing relatively high concentrations of micro and macro mineral elements, of rare earth elements, of calcium, and of silica. The mineral concentrations are produced by processing naturally occurring clay soil to concentrate mineral elements naturally occurring in the soil.

An interior sock is fabricated of a flexible elastic polymer. The interior sock has a cylindrical closed toe section, a cylindrical open ankle section and an intermediate heel section. The heel section is provided between the toe and ankle sections. An exterior sock is fabricated of a knitted blend of cotton and a minor portion of an elastic. The exterior sock has a cylindrical closed toe section, a cylindrical open ankle section and an intermediate heel section. The heel section is provided between the toe and ankle sections. A quantity of therapeutic fluid is located within the interior sock. The therapeutic fluid is in contact with a foot of a user. The interior sock provides support for the therapeutic fluid. The exterior sock provides pressure and warmth to the interior sock and the therapeutic fluid.

A method and device are provided for simultaneously or near-simultaneously diagnosing and treating tension pneumothorax and/or hemothoraxA Veress-type needle portion includes a hollow needle for puncturing the chest wall over a blunt hollow probe biased by one or more springs to extend distally into the pleural cavity. Openings in the blunt hollow probe connect via a pathway to an automatic check valve, which permits the flow of air and/or fluid only in a proximal direction. Pressure from within the pleural cavity is transmitted to the interior surface of a pressure documenter. If pressure greater than atmospheric pressure is present in the pleural cavity, the pressure documenter will be automatically urged proximally to simultaneously allow air and/or fluid to escape from the pleural space through the device, thus treating the tension pneumothorax and/or hemothorax, as well as providing a stable indicator to positively document the diagnosis of increased pressure.

Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, nutraceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures.

A method and apparatus for controlling a dose of extreme ultraviolet (EUV) radiation generated by a laser produced plasma (LPP) EUV light source. In one embodiment, a running total of the EUV energy generated over a predetermined number of laser pulses is measured; once that number of pulses is exceeded, the energy from the pulse immediately preceding the most recent predetermined number of pulses is dropped from the running total, so that the running total is from the most recent predetermined number of pulses. If the running total of the EUV energy exceeds a target dose, the next pulse is caused to not hit a droplet. This avoids the unwanted side effects of various prior art solutions, such as needing to miss many droplets in a row, or requiring the laser pulses to be shortened or reduced in power as in other prior art solutions.

The present application, pertaining to the field of slow neutron detection, relates to a slow neutron converter and a slow neutron detector. The slow neutron converter includes a substrate, the substrate including a plurality of holes extending along a first direction and insulating walls between the plurality of holes, wherein the plurality of holes are through holes. The slow neutron converter further includes a boron layer at least covering an exposed surface of the plurality of holes. The slow neutron converter and the slow neutron detector having the slow neutron converter according to the present disclosure are capable of maintaining a high slow neutron detection efficiency. In addition, the manufacturing complexity and manufacturing cost of the detector are reduced, and thus the effective, convenient and low-cost slow neutron detection is achieved.

An apparatus comprises a neutron detector. The neutron detector comprises a conversion layer comprising a mixture of a neutron absorbing material and a scintillation material; and a photodetector optically coupled to the conversion layer and arranged to detect photons generated as a result of neutron absorption events in the conversion layer; wherein the apparatus is adapted to be carried by a user and the conversion layer is positioned within the neutron detector such that when the apparatus is being carried by a user in normal use neutrons are absorbed in the conversion layer after passing through the user such that the user's body provides a neutron moderating effect. In some cases the apparatus may be carried in association with a backpack or clothing worn by a user, for example, the neutron detector may be sized to fit in a pocket. In other cases the apparatus may be a hand-held device with the conversion layer arranged within a handle of the device to be gripped by a user when being carried.

A heater in a housing with an opening. The heater reacts with oxygen to produce heat and upon consumption of the oxygen, the heating reaction stops and can be restarted at a later point in time upon the introduction of additional oxygen and is used in a package for heating pre-moistened substrates such as sanitary wipes, and the like.

The present invention relates to an in vitro method of diagnosing chronic myelomonocytic leukemia (CMML) in a subject, said method comprising the steps of: a) Detecting a monocyte population in a biological sample from said subject; b) Quantifying the CD14+/CD16− monocytes in said biological sample; c) Comparing the value of step b) to a reference value; and d) Diagnosing CMML based on said comparison. Preferably, said detecting step a) is performed by an exclusion gating strategy by flow cytometry.