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Graphical display for sorting and filtering a list in a space-constrained view

Techniques for sorting and filtering a list in a space-constrained viewing area are described. A filter widget and a list of items are displayed in a view of an electronic display screen. In response to user input selecting the filter widget, and without changing to a different view, a filter category overlay is displayed in the view to provide various selectable filter categories. In response to selection of a filter category, a visual depiction of the selected filter category is displayed in the view. The list of items is filtered according to the selected filter category and displayed in the view without changing to any other view. Subsequently added visual depictions are linearly stacked in the view. Further, a filter modification overlay, which provides selectable filtering attributes, is displayed upon selection of a visual depiction.




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Apparatus and method for user input for controlling displayed information

In accordance with an example embodiment of the present invention, a method for proximity based input is provided, comprising: detecting presence of an object in close proximity to an input surface, detecting a displayed virtual layer currently associated with the object on the basis of distance of the object to the input surface, detecting a hovering input by the object, and causing a display operation to move at least a portion of the associated virtual layer in accordance with the detected hovering input.




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Altering a view of a document on a display of a computing device

A document authoring program provides different views of a document opened by a user. In the editing view, the user can view the document contents and edit the contents in using a menu bar. In the semantic zoom view, the user is presented with a heading pane and a thumbnail pane and the menu bar is removed. The user can toggle from the editing view to the semantic zoom view by zooming out past a defined threshold using various user interface controls. Once the threshold is exceeded, the semantic view is presented. The editing view is returned to by selecting a heading or a thumbnail page, which respectively returns the user the page incorporating the selected heading or to the page incorporating the selected heading. This page will be displayed in the editing view at the same zoom level prior to toggling to the semantic zoom view.




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Translating user motion into multiple object responses

A system for translating user motion into multiple object responses of an on-screen object based on user interaction of an application executing on a computing device is provided. User motion data is received from a capture device from one or more users. The user motion data corresponds to user interaction with an on-screen object presented in the application. The on-screen object corresponds to an object other than an on-screen representation of a user that is displayed by the computing device. The user motion data is automatically translated into multiple object responses of the on-screen object. The multiple object responses of the on-screen object are simultaneously displayed to the users.




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Controlling the rendering of supplemental content related to electronic books

Architectures and techniques are provided to control the rendering of supplemental content associated with electronic books. For example, electronic books may be associated with content that is in addition to the content originally provided to an individual acquiring the electronic book, such as annotations, social networking site information, media outlet information, and the like. Individuals may control the supplemental electronic book content that is rendered via their client devices via actuation of a physical input device or a representation of an input device shown via a touch sensitive display. The amount of supplemental content that is rendered may correspond to information associated with a specified number of categories of supplemental electronic book content based on a supplemental content rendering level. In other implementations, the amount of supplemental electronic book content that is rendered may correspond to an amount of supplemental content to be rendered for each category of supplemental content.




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Minimizing and maximizing between portrait dual display and portrait single display

Methods and devices for minimizing and maximizing displayed output associated with applications are provided. More particularly, an application presented as two or more pages in a portrait mode can be minimized to present one of the two or more pages following a minimization operation. The page that continues to be displayed can comprise a primary or preferred page, while the page that is dismissed can comprise a secondary or ancillary page. With respect to a maximization operation received with respect to a page of an application results in the display of an additional page associated with that application. Maximization can include controlling the respective screens on which first and second pages of the maximized application are displayed.




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Process of producing phosphinothricin employing nitrilases

The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.




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Aminohydroxylation of alkenes

The invention relates to a process for the aminohydroxylation of alkenes using N-oxycarbamate reagents, e.g. N-acyloxycarbamate, N-alkyloxycarbonyloxycarbamate and N-aralkoxycarbonyloxycarbamate reagents. The invention particularly relates to an intermolecular aminohydroxylation reaction that can be carried out in the absence of added base. The invention also relates to novel N-oxycarbamate reagents that are stable crystalline materials. The process of the invention is useful in the synthesis of compounds having a vicinal amino alcohol moiety, such as biologically active compounds.




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Organophosphorus compounds, catalytic systems comprising said compounds and method of hydrocyanation or of hydroformylation using said catalytic systems

Organophosphorus compounds, catalytic systems comprising a metallic element forming a complex with the organophosphorus compounds and methods of hydrocyanation and of hydroformylation employed in the presence of the catalytic systems are described.




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Substituted phenylcarbamoyl alkylamino arene compounds and N,N'-BIS-arylurea compounds

Substituted phenylcarbamoyl alkylamino arenes; substituted phenylthiocarbamyl alkylamino arenes; substituted phenylcarbamoyl alkylamino heteroarenes; substituted phenylthiocarbamyl alkylamino heteroarenes; N-substituted aryl, N'-substituted aryl urea compounds; N-substituted aryl, N'-substituted heteroaryl urea compounds; N-substituted aryl, N'-substituted aryl thiourea compounds and N-substituted aryl, N'-substituted heteroaryl thiourea compounds are provided and may find use as androgen receptor modulators. The compounds may find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.




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Nitrate esters and their use for the treatment of muscle and muscle related diseases

Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula: wherein, R1 is ONO2, CH2ONO2, CnH2n+1OH, CnH2n+1OH, or CH2CH2CH3, or H;R2 is ONO2, CH2ONO2, Cn'H2n'+1OH, Cn'H2n'+1OH, CH2CH2CH3 or H; andR3 is ONO2, CH2ONO2, Cn'″H2n″+1OH, Cn″H2n″+1OH, CH2CH2CH3 or H; wherein n is an integer from 0 to 9, n' is an integer from 0 to 9, and n″ is an integer from 0 to 9, and n+n'+n″≦9, and wherein at least one of R1, R2, and R3 is an ester nitrate selected from the group consisting of ONO2, CH2ONO2, and combinations thereof.




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***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***Method for producing aqueous acrylamide solution

There is provided a method for producing an aqueous acrylamide solution by reacting a composition including acrylonitrile with water to produce acrylamide, in which the composition including acrylonitrile includes 3 to 15 mg of propionitrile per 1 kg of the total weight of the composition including acrylonitrile. According to the present invention, a production method with which it is possible to suppress acrylamide polymerization without lowering quality and thereby obtain a stable aqueous acrylamide solution can be provided.




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Method for producing aqueous acrylamide solution

There is provided a method for producing an aqueous acrylamide solution by reacting a composition including acrylonitrile with water to produce acrylamide, in which the composition including acrylonitrile includes 3 to 15 mg of propionitrile per 1 kg of the total weight of the composition including acrylonitrile. According to the present invention, a production method with which it is possible to suppress acrylamide polymerization without lowering quality and thereby obtain a stable aqueous acrylamide solution can be provided.




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Streaming playback and dynamic ad insertion

There is provided a system and method for dynamically generated client side streaming playlists. There is provided a method comprising receiving a request to stream a video asset for playback, retrieving, from a network, a video asset playlist corresponding to the video asset and an ad campaign playlist, generating a consolidated video playlist including the video asset playlist and the ad campaign playlist, and processing the consolidated video playlist using a media playback framework to stream a plurality of video files from the network for decoding and output to a display. Discontinuity tags within the video asset playlist may be utilized as insertion points for portions of the ad campaign playlist. The consolidated video playlist may be accessed through a local HTTP web server, advantageously allowing the use of commonly installed media playback framework models such as QuickTime X to trigger adaptive bitrate support through HTTP Live Streaming.




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Internet streaming and dynamic reconfiguration of user displays

Internet streaming from broadcast radio or television stations is described wherein triggers for dynamic content from internal or external systems cause an encoder system to generate command messages, and to optionally synchronize those command messages with any delays associated with the triggering events. Command messages are delivered through a streaming media distribution system to client media players which obtain or present the dynamic content, in association with any desired configuration changes to the appearance of the media player or the method or manner in which the dynamic content is presented.




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System and method for using state replication between application instances to provide a collaborative desktop environment

Described herein are systems and methods for enabling a collaborative remote desktop environment. The system includes a computing device and a first application instance that has an application state associated therewith. The first application instance includes, or is associated with, a current state component and application data/data files. The system further includes an application launcher that is used to instantiate a second application instance operating either on the same or on a different computing device. The second application instance similarly has an application state associated therewith and is associated with the application launcher. Upon receiving a request from the second user to interact with the first application instance, the application state and the application data/data files are communicated to the application launcher, and the application launcher instantiates the second application instance so that its state is substantially identical to that of the first application instance.




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Simulated network

Systems, methods, and computer-readable and executable instructions are provided for providing a simulated network. Providing a simulated network can include collecting a number of network parameters for a plurality of locations and determining an application frequency of an application for the plurality of locations. Furthermore, providing a simulated network can include providing a simulated network with the number of network parameters to a number of testers of the application, wherein the number of network parameters are provided proportionally to the application frequency.




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Policy control for encapsulated data flows

Systems and methodologies are described that facilitate communicating encapsulation information for a related mobility protocol type utilized in communicating over a data flow with reduced specific implementation on the policy server to support different mobility protocol types. In this regard, encapsulation information can be transmitted to the policy server from a network gateway such that the policy server can forward the encapsulation information to a serving gateway along with policy rules related to a data flow type. The serving gateway can utilize the encapsulation information to detect and interpret the encapsulated data flow according to the policy rules. In this regard, the serving gateway can provide support (e.g., quality of service support) for the flow. The encapsulation information can relate to a mobility protocol type, an encapsulation header, an indication that encapsulation is required, parameters regarding locating an encapsulation header in a message, and/or the like.




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Application programming interface, system, and method for collaborative online applications

An application framework including different application programming interfaces (APIs) is described which performs a variety of mobile device functions in response to API calls from applications. For example, in response to relatively simple API calls made by applications the application framework manages the complex tasks associated with invitations and matchmaking. By way of example, the details of complex transactions such as establishing peer-to-peer connections between mobile devices may be transparent to the application developer, thereby simplifying the application design process. The application framework may include an application daemon for communicating with a first set of services and an applications services module for communicating with a separate set of services. The application framework may also include a cache for caching data for each of the services based on different cache management policies driven by each of the services. The cache may be updated by push notification cache updates sent from each of the services.




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System and method for supporting video processing load balancing for user account management in a computing environment

A system and method can support user account management in a computing environment. The computing environment can include a video encoding pool to support load balancing and a managing server, such as a privileged account manager server. The video encoding pool includes a set of nodes that are able to perform one or more video processing tasks for another node. Furthermore, the managing server can receive a request from a managed node in the computing environment for delegating a video processing task, and can select one or more nodes from the video encoding pool to load babalance and to perform the video processing task.




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Calendar display apparatus

A calendar display apparatus includes a reference signal generator, a calendar data generator, and rotational display members. The reference signal generator generates a reference signal every period of 24 hours. The calendar data generator generates year, month, date, and day data upon reception of the reference signal. The rotational display members are driven by signals from the calendar data generator so as to display a year, a month, a date, and a day. A scale corresponding to the rotational display member for displaying years is constituted by multiple circular scales. Scale marks representing years are sequentially and continuously formed on the multiple circular scales from its inner circumference to outer circumferences.




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Method of depositing a decorative wear-resistant coating layer on a substrate

A method for depositing a wear-resistant decorative coating on a substrate, comprising a first stage of vacuum deposition on the surface of the substrate of a layer of at least one metal of the group titanium, zirconium, hafnium, vanadium, niobium, tantalum, chromium, molybedenum, tungsten and aluminium, to which is added at least one element of the group carbon, nitrogen, oxygen, boron, silicon, fluorine, chlorine, sulfur and phosphorus; a second stage including activation of the first layer by ionic bombardment under vacuum conditions and simultaneous deposition of a second fine layer of a metal or metal alloy; and a third stage involving galvanic deposition of a third layer of a decorative metal coating over the second layer.




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Speech recognition apparatus with means for preventing errors due to delay in speech recognition

When a speech sound of at least a predetermined sound pressure is externally input while a time measurement is not being performed, a time measuring circuit starts a time measurement responsive to a signal from a speech detector. When another speech sound of at least a predetermined sound pressure is externally input while a time measurement is being performed by the time measuring circuit, a measurement time measured by the time measuring circuit at this moment is stored in a time information memory. After a predetermined time has elapsed, if a speech recognition circuit recognizes that the externally input speech sound is a "stop" command, the time measurement operation performed by the time measuring circuit is stopped, and the time information stored in the time information memory is read out and displayed as measurement time information on a display unit.




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Automatic program ventilation control system

An automatic programmed ventilation control system for operating a fan includes a fan drive circuit; a duty, cycle control circuit including means for selecting a duty cycle and means for setting the selected duty cycle; a timing circuit including means for selecting the time of day and means for setting the selected time of day; a fan speed control circuit including means for selecting a fan speed and means for setting the selected fan speed; and a manual override switch circuit for overriding the set duty cycle and fan speed for operating the fan at a predetermined speed for a preselected period of time.




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Wind direction indicator and time display device for golf courses

A wind direction indicating and time display unit is provided for use at the tee areas of a golf course. The unit wind direction indicating device is mounted on an upper surface of a support structure and extends upwardly therefrom. The wind direction indicating device includes a support pole, a sleeve mounted for rotation on the pole at the top thereof, a wind direction indicating element, such as a flag, secured to the sleeve and movable in response to changes in wind direction, and a pole support fitting. Secured to the upper surface of the support structure. A time display device, such as a clock, is secured in a laterally facing wall surface of the support structure.




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Radio paging selective receiver with display for notifying presence of unread message based on time of receipt

A radio paging selective receiver determines that a received message is unread based on the time difference between the message reception time and the current time being larger that some predetermined value of time, and the paging selective receiver provides an indication of the unread message by displaying the reception time of the unread message in a second fashion which is visibly different from a first fashion normally used to display the current time.




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Analog wrist watch and pager providing message display on cover glass

An LCD is integrated with the cover glass of a wrist watch radio paging receiver which indicates the time data with a dial plate and hands, and a message is displayed on the cover glass by controlling this LCD. In this message display, the parts of the characters indicating the message are made transparent and the remaining parts intercept light. In this manner, message display is made possible by the difference in light transmissivity.




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Combined table lamp and clock assembly

A combined table lamp and clock assembly includes a lamp unit and a clock unit. The lamp unit includes a lamp stand base, a lamp stand, and a lamp bulb holder. The lamp stand base has a top side formed with a cavity, and a bottom side adapted to be placed on a table top. The lamp stand extends uprightly from the lamp stand base, and has an upper end portion and a lower end portion that is mounted on the top side of the lamp stand base. The lamp bulb holder is mounted on the upper end portion of the lamp stand, and is adapted for mounting a lamp bulb thereon. The clock unit includes a clock base, an upright clock panel, and a clock mechanism. The clock base is received in the cavity in the top side of the lamp stand base, and is formed with an insert slot therethrough. The upright clock panel has a lower end formed with an insert portion that is inserted removably into the insert slot. The clock mechanism is mounted on the clock panel.




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Method for producing display device

An object of the present invention is to provide a method for producing a display device by which a substrate is thinned efficiently. Onto one original substrate having an area for a plurality of display devices, the other original substrate is bonded via a sealing resin layer, the pair of bonded original substrates is divided and separated into a plurality of pairs of substrates of a size of each individual display device, and thereafter a substrate thinning process of thinning the substrates is performed in a state where the substrates are held by substrate holding means.




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Diurnal solar event triggering mechanism

A mechanism for determining whether the sun is visible at a diurnal solar event and for mechanically triggering actions based upon the sun being visible during the diurnal solar event is disclosed. The mechanisms of the invention can perform these operations without intervention or supervision for long periods of time. Certain embodiments have been applied to provide a diurnal solar event trigger based upon sidereal noon for a clock providing accurate timing for 10,000 years without intervention or supervision.




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Portable self contained light generating device powered by a flow of falling granular material

A portable self contained light generating device which is powered by a flow of granular material falling under the influence of gravity to impinge upon and cause a paddle wheel to rotate thereby turning a small generator producing electricity to power one or more light emitting diodes for illumination. The device equipped with a multi-position power/illumination control switch and in some embodiments also provided with a battery providing supplemental power.




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Coupled resonator for regulating system

The coupled resonator comprises a first low frequency resonator, such as a balance spring (1) and a second higher frequency resonator, such as a tuning fork (2), the two resonators (1 and 2) including permanent mechanical coupling means. Application to the regulating system of a timepiece.




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Wristwatch with atomic oscillator

A wristwatch, which comprises an atomic oscillator comprising a system for detecting the beat frequencies obtained by the Raman effect.




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Sliding-window multi-class striping

A sequence of storage devices of a data store may include one or more stripesets for storing data stripes of different lengths and of different types. Each data stripe may be stored in a prefix or other portion of a stripeset. Each data stripe may be identified by an array of addresses that identify each page of the data stripe on each included storage device. When a first storage device of a stripeset becomes full, the stripeset may be shifted by removing the full storage device from the stripeset, and adding a next storage device of the data store to the stripeset. A class variable may be associated with storage devices of a stripeset to identify the type of data that the stripeset can store. The class variable may be increased (or otherwise modified) when a computer stores data of a different class in the stripeset.




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Systems and methods for operating a flash memory file system

A flash memory file system including a plurality of flash modules. Each of the plurality of flash modules includes a respective cache memory, a respective flash memory, and a respective flash controller in communication with the respective cache memory and the respective flash memory. A first flash module of the plurality of flash modules is configured to receive a file lookup message including a path name for file data stored on a second flash module of the plurality of flash modules. A third flash module of the plurality of flash modules is configured to select the second flash module based on the path name and a directory table, and generate a file metadata message responsive to the file lookup message. The file metadata message identifies the second flash module as containing the file data.




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Moving blocks of data between main memory and storage class memory

An abstraction for storage class memory is provided that hides the details of the implementation of storage class memory from a program, and provides a standard channel programming interface for performing certain actions, such as controlling movement of data between main storage and storage class memory or managing storage class memory.




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Automatically preventing large block writes from starving small block writes in a storage device

A mechanism is provided in a storage device for performing a write operation. The mechanism configures a write buffer memory with a plurality of write buffer portions. Each write buffer portion is dedicated to a predetermined block size category within a plurality of block size categories. For each write operation from an initiator, the mechanism determines a block size category of the write operation. The mechanism performs each write operation by writing to a write buffer portion within the plurality of write buffer portions corresponding to the block size category of the write operation.




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Managing CPU resources for high availability micro-partitions

A partition manager relocates a logical partition from a primary shared processor pool to a secondary shared processor pool in response to a predetermined condition, such as a hardware failure. The relocated logical partition is allocated a smaller quantity of processing units from the secondary pool than it was allocated from the primary pool. A quantity of processing units reserved for a second logical partition is identified in the secondary shared processor pool, and a portion of those reserved processing units are allocated to the relocated logical partition. The reserved processing units may be redistributed among multiple relocated logical partitions.




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Process for recovering aliphatic monocarboxylic acids from distillation

A process is provided for recovering aliphatic monocarboxylic acids having from 4 to 11 carbon atoms from the distillation residue obtained in the oxidation of the corresponding aldehyde by means of oxygen or oxygen-containing gas mixtures in the presence of alkali metal carboxylates or alkaline earth metal carboxylates to form the corresponding monocarboxylic acid and subsequent distillation, characterized in that the distillation residue is reacted with an aqueous acid in a tube reactor and the two-phase mixture flowing out from the tube reactor is introduced into a settling vessel in which the organic phase which separates out has a pH of 4.5 or less.




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Bio-based terephthalate polyesters

Bio-based terephthalic acid (bio-TPA), bio-based dimethyl terephthalate (bio-DMT), and bio-based polyesters, which are produced from a biomass containing a terpene or terpenoid, such as limonene are described, as well as the process of making these products. The bio-based polyesters include poly(alkylene terephthalate)s such as bio-based poly(ethylene terephthalate) (bio-PET), bio-based poly(trimethylene terephthalate) (bio-PTT), bio-based poly(butylene terephthalate) (bio-PBT), and bio-based poly(cyclohexylene dimethyl terephthalate) (bio-PCT).




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Methanol carbonylation process with rhodium catalyst and a metallic co-catalyst selected from transition metals, zinc, beryllium, indium, tin, strontium and barium

A carbonylation process for making acetic acid using a metallic co-catalyst composition, effective as a rhodium stabilizer and/or rate promoter, at molar ratios of metal/rhodium of about 0.5 to 40. The process includes reacting methanol with carbon monoxide in the presence of a rhodium-based catalytic metal complex with about 1 to 20 weight percent methyl iodide, less than about 8 weight % water and about 0.5 to about 30 weight percent methyl acetate. The crude acetic acid is flashed and further purified.




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Alanyl glutamine compound and preparation method thereof

A process for preparing a pure alanylglutamine comprises the steps of: 1) reacting N-(α-chloro)-propionyl-glutamine and hydrazine compound to obtain an alanylglutamine crude product; 2) mixing anhydrous methanol and the alanylglutamine crude product to provide a filter cake; 3) dissolving the filter cake in water, heating, adding ethanol, and cooling to yield the pure alanylglutamine.




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Composition for maintaining function of platelets

A composition for maintaining a function of platelets, the composition comprising, as an active ingredient, a compound represented by the following general formula (I) or a salt thereof, or a solvate thereof: wherein X represents a phenylene group;Y represents any one of a hydrogen atom and —(CH2)mR1;wherein m represents an integer of any one of 0 to 4; andR1 is any one of —NR5COR2, —NR5SO2R2, and —NR3R4;wherein R2 represents any one of a C1 to C6 alkyl group, an aryl group, a C1 to C6 alkoxy group, and the like;R3 and R4 represent a C1 to C6 alkyl group or the like; andR5 represents any one of a hydrogen atom, a C1 to C6 alkyl group, and the like; and Z represents any one of a hydrogen atom and a C1 to C6 alkyl group.




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Process for the (AMM)oxidation of lower molecular weight alkanes and alkenes

A process for producing unsaturated carboxylic acids or unsaturated nitriles by vapor phase oxidation reaction of their corresponding C3 to C5 alkanes, C3 to C5 alkenes, and mixtures thereof, as a hydrocarbon starting material, wherein the process performance is monitored and the path of gasses through catalyst beds is altered. Improved catalyst lifetimes may be achieved.




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Hydrocarboxylation of aqueous formaldehyde using a dehydrating recycle stream to decrease water concentration

Disclosed is a process for the production and purification of glycolic acid or glycolic acid derivatives by the carbonylation of aqueous formaldehyde. The water in the hydrocarboxylation zone is reduced via reaction with the ester bonds in a recycle stream comprising glycolic acid oligomers and/or methyl glycolate oligomers.




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Antisense modulation of PTP1B expression

Provided herein are methods, compounds, and compositions for reducing expression of PTP1B mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate metabolic disease, for example, diabetes, or a symptom thereof.




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Macromolecular nucleotide compounds and methods for using the same

The invention describes new structures of the nucleotide conjugates (nuc-macromolecules) comprising at lease one nucleotide moiety coupled to at least one macromolecular compound via a short linker. These conjugates can be used as substrates for various kinds of polymerizing enzymes in the enzymatic synthesis of nucleic acids. In particular, these compounds can be used for labeling nucleic acids.




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Production of glucose from starch using alpha-amylases from Bacillus subtilis

An α-amylase from Bacillus subtilis (AmyE) produces significant amounts of glucose from various carbohydrate substrates, including vegetable starch, maltoheptaose, and maltotriose. Among other things, this advantageous property allows AmyE or variants thereof to be used in a saccharification reaction having a reduced or eliminated requirement for glucoamylase. The reduction or elimination of the glucoamylase requirement significantly improves the efficiency of the production of ethanol or high fructose corn syrup, for example.




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Cytosine analogue, a method of preparation of a cytosine analogue, a DNA methyltransferase 1 inhibitor, a method for DNA methylation inhibition, the use of the analogue in the treatment of diseases associated with deviations from normal DNA methylation

A cytosine analog, a method of preparation of a cytosine analog, a DNA methyltransferase 1 inhibitor, and a method for DNA methylation inhibition, is provided for the treatment of diseases associated with deviations from normal DNA methylation. The analog of cytosine may be comprised of 1, N4, 5 and 6-substituted derivatives of cytosine or 5,6-dihydrocytosine, wherein the analog can be described by the chemical formula where R1 is H, R3, R4, 2'-deoxyribosyl, R4 is alkyl or aryl, X is N or C, wherein if X in the analog of formula I is N, then R5 is no substituent and if X in the analog of formula I and/or II is C or if X in the analog of formula II is N, then R5 and R6 are independently alkyl, aryl, hydroxyalkyl, aminoalkyl, hydroxyl, carboxyl, amino group, alkoxyl, aryloxyl, aminoalkyl, aminoaryl, thio group, sulfonyl, sulfinyl or halogen.




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RNAi-mediated inhibition of frizzled related protein-1 for treatment of glaucoma

RNA interference is provided for inhibition of Frizzled Related Protein-1 mRNA expression, in particular, for treating patients having glaucoma or at risk of developing glaucoma.