Graffiti artists and muralists are sending messages of hope and despair with coronavirus public art

Why not use quarantine as an opportunity to have your homeschoolers master woodworking or engine repair?

The National Book Award winner's new book delves into matters of family grief and loss

An abstract aerial view of a sand dune at sunset at Imperial Sand Dunes, Glamis, California.

A Guanaco (Lama guanicoe) surveys its surroundings from a vantage point at sunset, with the imposing Torres del Paine (Chile) in the background. Scouts like this individual keep an eye out for predators.

A macro depiction of a beetle called Epilachna chrysomelina

Rice terraces in Longji,China.

Depicts a woman standing at the end of a staircase on the edge of a building, while the pipes coming from the structure continue on only to come to an end. The woman posing in the photo stares straight into the lens of the camera to emphasize the dividing nature of the image.

Anaconda Glacial Cave in Iceland

Pink flamingo greeting each other.

A sled in the Smithsonian collections marks the historic race

The National Trust for Historic Preservation is looking for 1,000 places tied to women's history, and to share the stories of the figures behind them

While COVID-19 has us homebound, it’s a good time to reflect on the peculiar histories of housewares we take for granted

The Beatles guitarist visited his sister in southern Illinois just months before he'd become world famous

During his 20-year professional career, his boisterous style endeared him to fans but rankled traditionalists

A filmed documentary on the University of Michigan 1970 environmental teach-in, asks the questions: Do teach-ins work? (The Bentley Historical Library at the University of Michigan)

In 1799, Alexander von Humboldt set foot in the jungles of Cumana, in present-day Venezuela. What ensued was a detailed scientific mission to learn more about the natural world.

Henry Ford spent the majority of the war as a pacifist. By 1917, however, his state-of-the-art assembly line was churning out vital engine parts to feed the war machine.

The smart tool gives users step-by-step instructions based on WHO’s handwashing protocol

Veteran musher Lance Mackey has had his 21st place finish in this year's Iditarod Trail Sled Dog Race vacated because of a failed drug test, race officials announced Thursday.

In a written decision released Thursday, a panel of three appeal court judges said the judge who granted the award to McCaw North Drilling and Blasting Ltd. misinterpreted a clause in the contract for the cleanup.

Yellowknife RCMP confirmed the death of the missing 22-year-old woman on Friday and charged 27-year-old Devon Larabie in connection with her death.

The N.W.T. and Nunavut Workers’ Safety and Compensation Commission says it filed multiple charges in the Nunavut Court of Justice under the Nunavut Safety Act on May 1.

The remote cabin could be the difference between life and death for travellers stuck on the territory’s long winter road. It was built to remember Stella Barnaby, who would have been 55 this Saturday.

The government of the Northwest Territories has made an exemption on border restrictions for a veterinarian from Alberta to practice in the territory, after he received public and political support.

Alcohol industry groups were successful in getting the Yukon government to pull labels warning of the connection between alcohol and cancer from liquor store shelves, but the strategy may have ultimately backfired, researchers suggest.

Schools were closed March 13 to reduce the risk of spread of the coronavirus, and there is no plan to reopen them by the end of the current school year in June.

A 19-year-old man was flown back to Ontario after he pleaded guilty to violating New Brunswick’s emergency measures order prohibiting visitors from entering the province.

Seven people were displaced by a fire early Saturday on the north end of Saint John.

Closing arguments were presented at the trial of Phillip Lionel Levac on Friday at Regina Court of Queen's Bench.

The premier’s office confirmed the news in an email statement, blaming visibility issues under "very specific lighting conditions."

Police in Thunder Bay have arrested and charged a man from the northwestern Ontario city following an investigation into allegations of child luring.

It's been more than a week since there were any new or active cases of COVID-19 in the catchment area for the Northwestern Health Unit (NWHU), and staff can not focus increasing testing.

<span class="topsy_trackback_comment"><span class="topsy_twitter_username"><span class="topsy_trackback_content">12 Cool India Facts [For President Obama's Visit] – RantRave ...: Washington Post12 Cool India Facts [For Presid... http://bit.ly/dmozLC</span></span>

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Green Depots will begin to reopen across the province on Monday, according to the Multi-Materials Stewardship Board, though dates and hours of operation may vary between sites. 

64-year-old John Neville, in agony and needing his wisdom tooth extracted, has been navigating a complex tangle of COVID-19 restrictions in an unsuccessful attempt at getting emergency dental care.

Philip Pynn is being released from federal prison for a second time, after breaching conditions landed him back behind bars last year — but it's not clear where he can live.

Staff halted $100 service over pandemic concerns, forcing homeowners to private plumbers much more, and Danny Breen is urging them to contact the city.

The Art Zone is a place where teens can creatively express themselves and their worship for God. For Saskia, art is a way to quiet her mind and let God speak.

"It is unfortunate that it has come to pass that we have to collectively and overtly publicly declare that we are unified," says Alberta Medical Association president Christine Molnar.

Police are investigating a report of a suspicious package in north Edmonton.

Tensions are rising on Manitoulin Island because a First Nation is stopping travellers on provincial highways that go through the community. But opinions on M'Chigeeng's attempt to protect its people from COVID-19 are not divided along racial lines. 

The head of a Sudbury-based book publishing company says she’s shifting launches online due to COVID-19.

The following is a guest post by Martha H. Kennedy, Curator of Popular & Applied Graphic Art, Prints & Photographs Division. During Will Eisner Week, March 1-7, 2020, the Library of Congress joins art schools, libraries, universities, and museums in a global celebration of this legendary creator’s contributions to the world of comic art and […]

Below is an interview with Elizabeth Lindqwister, the summer 2019 Liljenquist Family Fellow, and Prints & Photographs Division staff members, Karen Chittenden and Micah Messenheimer, about creating a Story Map focusing on the Civil War experience of Susie King Taylor. Many courageous people are pulling double and triple duty in this time of quarantine for […]

Differential detergent fractionation of cells is a rapid method for extraction of cytoplasmic and nuclear proteins in preparation of an immunoprecipitation. This method can be applied for use of adherent or suspension cells and can significantly reduce nonspecific background in an immunoprecipitation by separation of cellular compartments into individual fractions. The lysis of cells by differential detergents permits the rapid extraction of proteins from the cytoplasm (digitonin), the cytoplasmic membranes, and organelles (Triton X-100), and nucleoplasm (Tween/DOC), facilitated through the use of distinct extraction buffers. Cytoplasmic and nuclear matrix proteins as well as DNA are left behind during the detergent-based extraction.

This rapid and efficient method to prepare highly purified recombinant adeno-associated viruses (rAAVs) is based on binding of negatively charged rAAV capsids to an anion-exchange resin that is pH dependent.

In this protocol, DNA fragments are separated according to size by electrophoresis through low-melting-temperature agarose, and then recovered by melting the agarose and extracting with phenol:chloroform. The protocol works best for DNA fragments ranging in size from 0.5 to 5.0 kb. Yields of DNA fragments outside this range are usually lower, but often are sufficient for many purposes.