and FILTERING APPARATUS, SPRINKLING APPARATUS INCLUDING THE FILTERING APPARATUS, AND FILTERING METHOD By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention provides a filtering apparatus, a sprinkling apparatus using the filtering apparatus, and a filtering method. The filtering apparatus includes a liquid passage chamber, a drainage chamber, and a recirculation chamber. The sprinkling apparatus further includes a jetting section. The filtering method includes the steps of closing a liquid passage hole, filtering a liquid, and flowing the liquid in to a compartment chamber while discharging filter residue. Full Article
and INTANK FILTER BOWL DE-AERATION OUTLET SHROUD AND FILTER BOWL AND FILTER ASSEMBLY INCLUDING THE SAME By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT An in-tank filter bowl de-aeration shroud for a hydraulic or oil reservoir includes an outlet shroud surrounding the filter bowl outlet at a proximal end thereof and having a shroud fluid outlet at a distal end thereof with a larger opening than an opening of the filter bowl outlet. The outlet shroud may be formed as or include a diverging member surrounding the filter bowl outlet at a proximal end thereof and having a diverging member fluid outlet at a distal end thereof, wherein the member diverges from the proximal end to the distal end thereof. The outlet shroud may further include a central deflector positioned within the diverging member and combining with the diverging member to form an annular passage to the diverging member fluid outlet. Full Article
and FILTER METHOD FOR FILTERING A FLUID AND FILTERING DEVICE FOR FILTERING A FLUID By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT a filtering method, with which a fluid to be filtered is led through a filter (4), the filter (4) is back-flushed at regular time intervals and a pre-treatment agent is added to the fluid at the entry side of the filter. A process variable which describes the efficiency of the filtration is continuously computed during the filtration, and a metering quantity of the pre-treatment agent is reset on the basis of the values for the process variable or a characteristic values derived from this. Full Article
and WATER TREATMENT METHOD AND WATER TREATMENT APPARATUS EACH USING MEMBRANE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Ozonated washing water is generated by injecting an ozone gas into pressurized washing water that is filtered water obtained by membrane filtration of untreated water and that is to be used at the time of backwashing, and the ozonated washing water is supplied to a membrane from the filtration secondary side to thereby remove a fouling substance inside the membrane, while causing ozone-containing bubbles to emerge in the filtration primary side to thereby remove a fouling substance on a membrane surface in the filtration primary side. Full Article
and Integral 3D graphene-carbon hybrid foam and devices containing same By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Provided is an integral 3D graphene-carbon hybrid foam composed of multiple pores and pore walls, wherein the pore walls contain single-layer or few-layer graphene sheets chemically bonded by a carbon material having a carbon material-to-graphene weight ratio from 1/100 to 1/2, wherein the few-layer graphene sheets have 2-10 layers of stacked graphene planes having an inter-plane spacing d002 from 0.3354 nm to 0.40 nm and the graphene sheets contain a pristine graphene material having essentially zero % of non-carbon elements, or a non-pristine graphene material having 0.01% to 25% by weight of non-carbon elements wherein said non-pristine graphene is selected from graphene oxide, reduced graphene oxide, graphene fluoride, graphene chloride, graphene bromide, graphene iodide, hydrogenated graphene, nitrogenated graphene, doped graphene, chemically functionalized graphene, or a combination thereof. Also provided are a process for producing the hybrid form, products containing the hybrid foam, and its applications. Full Article
and THERMO-SENSITIVE WATER ABSORBENT, METHOD OF WATER TREATMENT, AND WATER TREATMENT APPARATUS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A thermo-sensitive water absorbent is used as a draw material in production of fresh water by a forward osmosis process. The thermo-sensitive water absorbent has a cloud point, and coagulates when heated, the thermo-sensitive water absorbent being a block copolymer containing at least a hydrophobic part and a hydrophilic part, having a glycerin structure as a basic structure, and including an ethylene oxide group and a group consisting of propylene oxide and/or butylene oxide. Full Article
and Systems and arrangements for mitigating environmental damage caused by storm water carried pollution By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A pollution mitigation system is disclosed. The system can include a valve forming a passage the valve installable to form an orifice in a storm drain retention chamber that passes storm water into a conduit of a storm water management system. The valve having a stem connected to a closure member that can plug the orifice. The valve can have a spring loaded actuator that can move the closure member into a closed position. The system can also include a node such as a wireless sensor node or a mote that has sensors, a transceiver, an antenna, a microcontroller, memory, an energy source and at least one output to control movement of the closure member via the preloaded actuator. The node can have an output that provides the stimulus to the preloaded actuator to cause the preloaded actuator to move the closure member to a position that obstructs the passage in response to either the sensor or a transmission from a mobile telephone such as a cell phone or a smartphone. Full Article
and DEVICE AND METHOD FOR TREATING LIQUIDS BY MEANS OF OZONE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A method for treating contaminated liquids in a flow by ozone, wherein the ozone is fed in gas form into the flow at one point and then is mixed into the flow in stages by mixers following one another in the flow direction, so that an absolute quantity of introduced ozone increases after each mixer until a feed efficiency of more than 95 percent is reached. Full Article
and FILTER AND FILTERING ARRANGEMENT By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A filter for filtering pyrolysis oil and an arrangement. The filter is a split-flow filter (1, 1a, 1b), comprising a filter element (12), comprising plurality of apertures (17) extending through the filter element (12), a receiving channel (13) for receiving a flow (F) of pyrolysis oil to be filtered and for supplying said flow on first side (A) of the filter element (12), a main discharge channel (14) arranged on the first side (A) of the filter element (12) for discharging the portion of the flow (F) of pyrolysis oil having not penetrated through the filter element (12), and a filtrate channel (15) arranged on second side (B) of the filter element (12) for discharging the portion of the flow (F) of pyrolysis oil having penetrated through the filter element (12). Full Article
and PLANT AND METHOD FOR MELTING AND CLEANING OF SNOW AND ICE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Plant for melting and cleaning of snow and ice, distinguished in that the plant comprises a means for melting using enthalpy of a water source in order to melt snow and ice, and a means for cleaning for cleaning out the pollution from the water phase that contains the melted snow and ice. Method for melting and cleaning of snow and ice, using the plant according to the invention. Full Article
and Waste and/or Hazardous Liquid Containment and Collection System By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT 5 A liquid cleaning system rests on a surface having a non-porous material covering and a drain. A lower plate layer and an upper plate layer each have runners arranged in a grid. The lower plate layer rests upon the surface and the upper plate layer rests upon the lower plate layer offset at an angle with respect to the grid of the lower plate layer. An upper layer covers the upper plate layer and has a plurality of holes for the passage of fluids into the liquid cleaning system. As liquid enters the liquid cleaning system through the holes, the liquid traverses the grid of the lower plate layer and the grid of the upper plate layer flowing towards the drain, and contaminants within the liquid collect within the grid of the lower plate layer and the grid of the upper plate layer. Full Article
and Autumn Lights Festival Dazzled Oakland By www.eastbayexpress.com Published On :: Mon, 19 Oct 2015 13:23:00 -0700 If you could get through the long line, the Oakland Autumn Lights Festival dazzled with both large- and small-scale light installations woven into the greenery at the Gardens at Lake Merritt. Full Article Blogs/Arts & Music
and Friday’s FTP Rally Shows Schaaf Has Abandoned Her Nighttime Street March Ban By www.eastbayexpress.com Published On :: Mon, 23 Nov 2015 17:05:00 -0800 Roughly fifty demonstrators marched from Fruitvale BART on Friday night to Oakland City Hall in an anti-police rally called in response to the fatal shooting of Richard Perkins by Oakland police on November 15. But unlike protests earlier this year, police didn’t try to drive demonstrators onto the sidewalks to comply with Oakland Mayor Libby Schaaf’s policy banning nighttime street marches.… Full Article Blogs/News
and Boxing Night at 16th Street Station in West Oakland By www.eastbayexpress.com Published On :: Tue, 21 Jun 2016 18:00:00 -0700 A recent boxing showcase at a defunct West Oakland train station captured the historic spirit of the site. On Saturday June 11, Osric Pratt Promotions presented Unfinished Business, a showcase of Northern California boxing culture at the historic 16th Street train station in West Oakland. The event consisted of seven boxing matches, interspersed with hip-hop and poetry performances.… Full Article Arts & Culture/Culture Spy
and Jet Martinez Brings a Floral Green Flash to Downtown Oakland By www.eastbayexpress.com Published On :: Fri, 08 Jul 2016 13:44:00 -0700 Last week, Oakland artist Jet Martinez finished his largest mural yet, on the side of the I. Magnin Building in downtown Oakland — to stunning effect. The Mexico-born artist is known internationally for his gorgeous floral patterning inspired by motifs in Mexican folk art. But, according to a recent statement released about his new mural, he recently decided he wanted to contribute more directly to the community in which he lives by doing more local art.… Full Article Blogs/Arts & Music
and This Year’s Oakland Music Festival Was a Marathon of Small, Local Gigs By www.eastbayexpress.com Published On :: Mon, 10 Oct 2016 18:29:00 -0700 Jay Stone looked at home as he took the stage in a burgundy bathrobe last Thursday at The Night Light, a bar near Jack London Square.… Full Article Blogs/Arts & Music
and This Year's Oakland Music Festival Was a Marathon of Small, Local Gigs By www.eastbayexpress.com Published On :: Wed, 12 Oct 2016 01:00:00 -0700 Despite some growing pains, the fest successfully expanded into a ten-day concert series that highlighted outstanding local talent. Jay Stone looked at home as he took the stage in a burgundy bathrobe last Thursday at The Night Light, a bar near Jack London Square. He was headlining the seventh night of Oakland Music Festival, which dominated the local concert calendar from September 30 to October 9 with shows taking place at different venues every night.… Full Article Music/Music
and Treasure Island Music Festival Made a Valiant Attempt to Weather the Storm By www.eastbayexpress.com Published On :: Tue, 18 Oct 2016 18:30:00 -0700 Kamaiyah, Ice Cube, How to Dress Well, and Sigur Rós played in the rain despite the many delays, cancelations, and technical difficulties. Treasure Island promised one of its best lineups yet for its tenth anniversary, but severe weather literally rained on everyone's parade. Many performances were delayed or canceled, often with little communication to the public on Saturday.… Full Article Music/Music
and Bay Area Activists Protest Peter Thiel's Partnership With Immigration and Customs Enforcement By www.eastbayexpress.com Published On :: Tue, 14 Mar 2017 16:52:00 -0700 'Don’t build technology for Mordor.' On Saturday at Peter Thiel’s San Francisco home overlooking the Bay, protesters demonstrated against a collaboration between Immigration and Customs Enforcement and Palantir Technologies, a data-mining firm that Thiel co-founded. As reported in The Intercept, ICE will be using a new Palantir product called Investigative Case Management to to aid in its expanded deportation mission.… Full Article News & Opinion/News
and Photos from the ANSWER and Indivisible Counter-Protests Against ACT for America's 'March Against Sharia' By www.eastbayexpress.com Published On :: Mon, 12 Jun 2017 08:52:00 -0700 ACT for America, which the Southern Poverty Law Center has designated as an anti-muslim hate group, showed up on Saturday morning in cities nationwide, dubbing its protest a "March Against Sharia." Berkeley was spared, but the group appeared in nearby Santa Clara, and in Roseville, a suburb of Sacramento.… Full Article Blogs/News
and Photos: Warriors Celebrate Second Title in Three Years with Parade and Rally in Oakland By www.eastbayexpress.com Published On :: Fri, 16 Jun 2017 12:04:00 -0700 The Golden State Warriors paraded for the second time in three years in downtown Oakland yesterday. Players rode by in topless busses, paired with teammates and families, along with coaches, members of the team's ownership group, and of course the odd ambassadorial pairing of Mayor Libby Schaaf and MC Hammer.… Full Article Blogs/News
and The Complex Hustle of Oakland's BART Dancers By www.eastbayexpress.com Published On :: Wed, 04 Oct 2017 01:00:00 -0700 Turf dancing has become ubiquitous on the trains, providing steady income, a creative platform, and a built-in audience. On a recent Friday, Yaameen Muhammad stood on the West Oakland BART platform, the afternoon sun reflecting off his neon-yellow high-tops.… Full Article Arts & Culture/Arts Feature
and Photo Essay: On #510Day Our People Are Oakland By www.eastbayexpress.com Published On :: Fri, 11 May 2018 12:15:00 -0700 Recently, a video where a woman called the police on a Black family who was barbecuing at Lake Merritt went viral, and several local and national outlets published pieces on the outraging incident.… Full Article Blogs/Arts & Music
and Photos from the Warriors' 2018 Championship Parade in Oakland By www.eastbayexpress.com Published On :: Tue, 12 Jun 2018 19:41:00 -0700 Here are photos from today's Warriors' championship parade. Full Article Blogs/News
and SF’s Lava Mae Brings Showers, ‘Radical Hospitality’ to Oakland Homeless Encampments By www.eastbayexpress.com Published On :: Thu, 25 Oct 2018 11:45:00 -0700 The organization sets up at 27th Street and Northgate Avenue and at 6th and Castro streets. Blair Hippolyte and Jannie Rutledge, two Oakland residents who are homeless, sat on the sidewalk of 27th Street.… Full Article News & Opinion/Feature
and War and Peace By www.eastbayexpress.com Published On :: Fri, 21 Feb 2020 01:00:00 -0800 Beanpole sees post-WWII Russia through the eyes of two emotionally drained women. The scene is the former Leningrad in 1945, a few weeks after the close of World War II. The characters in Kantemir Balagov’s Beanpole are what’s left after the horrendous two-and-a-half-year siege of the city by the German invaders, in which some 800,000 civilians perished from cold and hunger.… Full Article Movie Review
and Hollow-Point Rounds in the Holy Land By www.eastbayexpress.com Published On :: Wed, 04 Mar 2020 01:00:00 -0800 Israeli film Incitement traces the trajectory of a rightwing terrorist. Yaron Zilberman's Incitement is a fine example of the dramatized history lesson that fills in the gaps of our knowledge on the subject of who did what to whom, and why, in the seemingly eternal political turmoil of modern-day Israel. In this case the subject is the 1995 assassination of Israeli Prime Minister Yitzhak Rabin, a crime committed to avenge Rabin's rapprochement with the Palestinian people — with the emphasis on the assassin, a religiously motivated young Jewish idealist named Yigal Amir.… Full Article Movie Review
and With Graffiti Pizza, Old Oakland Gets a Much-Needed Late-Night Slice House By www.eastbayexpress.com Published On :: Wed, 04 Mar 2020 01:00:00 -0800 From plain cheese slices to pan pizza to slices drizzled with balsamic reduction, Graffiti Pizza has you covered. After the clock strikes midnight in Oakland, there's no shortage of tacos, burritos, or won ton noodle soup. But one of the most classic of late-night foods — pizza by the slice — was hard to find in Oakland during the wee hours.… Full Article Restaurant Review
and Which Restaurants Are Open For Deliveries and Take-Out? By www.eastbayexpress.com Published On :: Wed, 25 Mar 2020 01:00:00 -0700 The chamber of commerce is maintaining a list of local eateries still open for business. The Oakland Chamber of Commerce has compiled a list of more than 175 Oakland restaurants offering takeout or home delivery. The City of Alameda had a similar idea, and has created a website listing about 85 restaurants.… Full Article Restaurant Review
and Oakland's Cream Co. Meats Now Sells Retail and Delivers By www.eastbayexpress.com Published On :: Wed, 01 Apr 2020 04:00:00 -0700 Oakland-based Cream Co. Meats announced recently that, for the first time ever, it will start delivering its products on a retail basis. Statewide Covid-19-related shelter-in-place regulations mandated the closure of many restaurants and other businesses that regularly serve and sell Cream Co. products.… Full Article Food News
and Crowd-Sourcing an Oakland Grammy Nomination By www.eastbayexpress.com Published On :: Wed, 01 Jan 2020 04:00:00 -0800 Oakland’s Alphabet Rockers lands a second nomination for best children’s music album for record honoring gender and cultural diversity. The motto of the Alphabet Rockers is: "We make music that makes change." On its most recent album, The Love, the Oakland hip-hop collective lives up to that promise.… Full Article Music/Music
and Hot Highlights of Oakland Restaurant Week By www.eastbayexpress.com Published On :: Wed, 08 Jan 2020 01:00:00 -0800 Oakland Restaurant Week is more than just about eating great food. The program, presented by Visit Oakland in partnership with See Eat Love, also celebrates the history of cuisine in The Town so that diners can learn the stories behind their meals and get rare peeks at behind-the-scenes events. ORW20 - 15sec from Visit Oakland on Vimeo. Oakland Restaurant Week is more than just about eating great food.… Full Article (Sponsored)
and SYSTEMS FOR HANDLING MICROFLUIDIC DROPLETS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The invention generally relates to assemblies for displacing droplets from a vessel that facilitate the collection and transfer of the droplets while minimizing sample loss. In certain aspects, the assembly includes at least one droplet formation module, in which the module is configured to form droplets surrounded by an immiscible fluid. The assembly also includes at least one chamber including an outlet, in which the chamber is configured to receive droplets and an immiscible fluid, and in which the outlet is configured to receive substantially only droplets. The assembly further includes a channel, configured such that the droplet formation module and the chamber are in fluid communication with each other via the channel. In other aspects, the assembly includes a plurality of hollow members, in which the hollow members are channels and in which the members are configured to interact with a vessel. The plurality of hollow members includes a first member configured to expel a fluid immiscible with droplets in the vessel and a second member configured to substantially only droplets from the vessel. The assembly also includes a main channel, in which the second member is in fluid communication with the main channel. The assembly also includes at least one analysis module connected to the main channel. Full Article
and METHODS AND COMPOSITIONS FOR PREDICTING TOBACCO USE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Provided herein are methods of reliably determining whether or not an individual is a user of tobacco. Full Article
and MUTATIONS OF THE PARKIN GENE, COMPOSITIONS, METHODS AND USES By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The invention concerns nucleic acids coding for mutated or truncated forms of the human parkin gene, or forms comprising multiplication of exons, and the corresponding proteins and antibodies. The invention also concerns methods and kits for identifying mutations of the parkin gene, and for studying compounds for therapeutic purposes. Full Article
and Process, Apparatus or System and Kit for Classification of Tumor Samples of Unknown and/or Uncertain Origin and Use of Genes of the Group of Biomarkers By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention refers to a process for classifying tumor samples of unknown and/or uncertain primary origin, specifically including the steps of obtaining patterns of biological activity modulation of tumor of unknown and/or uncertain primary origin and comparing them to an specific and unique group of biomarkers which determine the profiles of biological activity modulation of known origin tumors. The present invention belongs to the molecular biology and genetics field. Full Article
and METHODS AND COMPOSITIONS RELATING TO FUSIONS OF ALK FOR DIAGNOSING AND TREATING CANCER By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Disclosed are methods and compositions for detecting the presence of a cancer in a subject and assessing the efficacy of treatments for the same. The disclosed method use reverse transcription polymerase chain reaction (RT-PCR) and multiplex polymerase chain reaction techniques as well as Template Exchange Extension Reaction (TEER) to detect the presence of point mutations, truncations, or fusions of anaplastic lymphoma kinase. Full Article
and CANCER PROGRESSION OBSERVATION INDEX GENE GROUP AND METHOD OF DETECTING THE GENE GROUPS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A method of detecting a cancer progression observation index gene group, comprising: a) preparing a plurality of AKR/J mice in which an oncogene is inserted into a thymocyte; b) dividing the AKR/J mice into three groups, raising the first group of the AKR/J mice after high-dose ionizing radiation of 0.8 Gy/min, raising the second group of the AKR/J mice after low-dose ionizing radiation of 0.7 mGy/hr, and raising the third group of the AKR/J mice in a general environment; c) obtaining a thymus of a dead mouse of the first or second group of the AKR/J mice throughout the b) operation and diagnosing cancer when a weight of the thymus is increased to twice or more than before radiation; d) extracting thymuses by sacrificing the first to third groups of the AKR/J mice at the time at which the third group of the AKR/J mice initially die; and e) selecting only a thymus having no change in weight compared to the organs of the same-aged non-irradiated AKR/J mice from the organs extracted in d) and detecting a gene of the organ whose weight is increased or decreased by a factor of two or more through gene analysis. Full Article
and UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT In some embodiments, the present disclosure pertains to a method for retrieving at least one molecular recognition element in a fixed tissue. In some embodiments the method comprises preparing a solution comprising at least one aldehyde-scavenging agent. In some embodiments, the method comprises contacting the fixed tissue with the solution. In some embodiments, the tissue is fixed with an aldehyde-based cross-linking agent. In some embodiments, a reaction of the aldehyde-scavenging agent with the aldehydes comprising the cross-linking agent retrieves the at least one molecular recognition t. In some embodiments, the at least one rolecular recognition element comprises of amino acids, peptides, proteins, nucleic acids, carbohydrates, lipids, or a combination thereof. In some embodiments, the at least one aldehyde-scavenging agent comprises of beta-dicarbonyl compounds, mono or di-amide scavengers, ethyl alcohols, sulfur containing compounds, mercaptoethylamines, mercaptoethanols, hydrazines, ethanolamines, hydroxylamines, anilines, variation of amines, activated charcoal, phenols, or mixtures and combinations thereof. Full Article
and COMPOSITIONS, METHODS, AND SYSTEMS FOR TISSUE FIXATION By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present disclosure relates to use of high-concentration aldehyde-based fixatives to fix tissue samples. Aldehyde concentrations are selected that significantly increase rate of diffusion of the fixative solution into the tissue. When combined in the cold-temperature step of a two-temperature fixation, a substantial improvement in the preservation of post-translationally modified proteins is achieved. Full Article
and Novel Gold Nanostructures and Methods of Use By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The invention is drawn to novel nanostructures comprising hollow nanospheres and nanotubes for use as chemical sensors, conduits for fluids, and electronic conductors. The nanostructures can be used in microfluidic devices, for transporting fluids between devices and structures in analytical devices, for conducting electrical currents between devices and structure in analytical devices, and for conducting electrical currents between biological molecules and electronic devices, such as bio-microchips. Full Article
and Screening Assay for Choice of Prebiotic to Prevent/Treat Gastrointestinal and Systemic Diseases By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided. Full Article
and LIGHT HARVESTING MULTICHROMOPHORE COMPOSITIONS AND METHODS OF USING THE SAME By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Light harvesting luminescent multichromophores that are configured upon excitation to transfer energy to, and amplify the emission from, an acceptor signaling chromophore in energy-receiving proximity therewith are provided. Also provided are compositions for labelling a target. The labelling composition may include a donor light harvesting multichromophore and an acceptor signaling chromophore in energy-receiving proximity to the donor light harvesting multichromophore. Also provided is an aqueous composition for labelling a target, including: a donor light harvesting multichromophore; an acceptor signaling chromophore in energy-receiving proximity therewith; and a sensor biomolecule. Methods for using the subject compositions are also provided. Full Article
and NOVEL METHOD FOR DETECTING DETECTION OBJECT IN SAMPLE, AND DETECTION KIT USING SAME By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention relates to a novel method for detecting a detection object in a sample, and a detection device using the same. The detecting method of the present invention uses a “bridge composite” in which gold nanoparticles and an antibody specific to a detection object are coupled in order to induce a sufficient coupling reaction between the antibody and the detection object, thereby improving reactivity. Accordingly, since excellent resolution is provided, the method of the present invention has advantages of enabling accurate concentration measurement of a detection object in a sample, and amplifying a measurement signal. In addition, the method of the present invention can effectively detect small molecules such as hormones, vitamins, etc. having a small molecular weight. Full Article
and SENSING SENSOR AND SENSING DEVICE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A sensing sensor includes a wiring board, a piezoelectric resonator, a channel forming member, a case body, and a regulating portion. The case body houses the wiring board, the piezoelectric resonator, and the channel forming member. The case body includes a window faced to a region including the output terminal on the another surface side of the wiring board and an injection port supplying a supply liquid to the one end side of the channel. The regulating portion is disposed in the case body. The regulating portion regulates the wiring board from the one surface side when the wiring board is pressed from the another surface side. The piezoelectric resonator is pressed against the surrounding portion by the output terminal being pressed from the another surface side. Full Article
and COMPOSITIONS AND METHODS FOR AUTOIMMUNE DISEASE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease. Full Article
and Assays for the Detection of Anti-TNF Drugs and Autoantibodies By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention provides assays for detecting and measuring the presence or level of anti-TNFα drug therapeutics and autoantibodies in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNFα drug therapeutics to detect the presence or level of autoantibodies (e.g., HACA and/or HAHA) against the drug. Full Article
and SOLUBLE AND IMMUNOREACTIVE VARIANTS OF HTLV CAPSID ANTIGEN P24 By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The invention concerns soluble and antigenic HTLV p24 variants that can be fused to chaperones and their use in diagnostic applications such as immunoassays for detecting antibodies against HTLV-I or HTLV-II in an isolated biological sample. In particular, the invention relates to a soluble HTLV-I or HTLV-II p24 antigen comprising either the N- or the C-terminal domain of p24 and lacking the other domain. Moreover, the invention covers recombinant DNA molecules encoding these HTLV-I and -II fusion antigens as well as their recombinant production using expression vectors and host cells transformed with such expression vectors. In addition, the invention focuses on compositions of these HTLV p24 antigens with HTLV gp21 antigen and on an immunoassay method for detection of HTLV antibodies using the antigens of the invention. Also the use of HTLV p24 antigens in an in vitro diagnostic assay as well as a reagent kit for detection of anti-HTLV-antibodies comprising said HTLV antigens is encompassed. Full Article
and METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. Full Article
and MATERIALS AND METHODS FOR DIAGNOSIS, PROGNOSIS AND ASSESSMENT OF THERAPEUTIC/PROPHYLACTIC TREATMENT OF PROSTATE CANCER By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A method to detect prostate cancer comprising contacting a sample of prostate cells from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in prostate tumor tissue, PIN (intra-epithelial neoplasia), histologically benign tissue and benign prostatic hyperplasia (BPH); a method to combine immunofluorescence and FISH (IF-FISH) to facilitate the assessment of chromosomal abnormalities; a set of probes; and a kit comprising the set of probes and instructions for diagnosing prostate cancer in a patient. Full Article