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Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




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Potential through simplicity: thymidine kinase-1 as a biomarker for CDK4/6 inhibitors




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Comparative efficacy of a hydroxyapatite and a fluoride toothpaste for prevention and remineralization of dental caries in children




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A single-centre investigator-blinded randomised parallel-group study protocol to investigate the influence of an acclimatisation appointment on children’s behaviour during N<sub>2</sub>O/O<sub>2</sub> sedation as measured by psycho




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Clinical and radiographic evaluation of indirect pulp treatment of young permanent molars using photo-activated oral disinfection versus calcium hydroxide: a randomized controlled pilot trial




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Analysis of different characteristics of smile




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Viral contamination in biologic manufacture and implications for emerging therapies




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Author Correction: Genetic circuit design automation for the gut resident species <i>Bacteroides thetaiotaomicron</i>




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Effect of simulated microgravity on the antidiabetic properties of wheatgrass (<i>Triticum aestivum</i>) in streptozotocin-induced diabetic rats

npj Microgravity, Published online: 24 February 2020; doi:10.1038/s41526-020-0096-x

Effect of simulated microgravity on the antidiabetic properties of wheatgrass (Triticum aestivum) in streptozotocin-induced diabetic rats




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Growth of microorganisms in an interfacially driven space bioreactor analog

npj Microgravity, Published online: 08 April 2020; doi:10.1038/s41526-020-0101-4

Growth of microorganisms in an interfacially driven space bioreactor analog




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Cobaltaelectro-catalyzed C–H activation for resource-economical molecular syntheses




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Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity




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Author Correction: Guidance for quantitative confocal microscopy




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High rate of durable remissions post autologous stem cell transplantation for core-binding factor acute myeloid leukaemia in second complete remission




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Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




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Rituximab for desensitization during HLA-mismatched stem cell transplantation in patients with a positive donor-specific anti-HLA antibody




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells




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LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression




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MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer

Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers.




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Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs

miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors.




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Nanomolar-scale, high throughput chemical synthesis of drug-like molecules

A high throughput, miniaturized chemical synthesis platform could enable rapid discovery of lead compounds.




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c-jun N-terminal kinase (JNK); MAP kinase 1 (MAPK1; ERK-2); MAPK3 (ERK-1)

In vitro and rodent studies suggest ophiopogonin D could help prevent doxorubicin-induced cardiotoxicity.




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Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4

Mouse studies suggest chemically modified carbohydrate conjugates could be useful as antigens for the development of cancer vaccines.




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Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis




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MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis




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Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice




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TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials




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Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism




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Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy




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Microbiota and colorectal cancer: colibactin makes its mark




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Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions




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Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys




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A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies




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Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression




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Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial




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Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis




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SIN List criticism based on misunderstandings




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Author Correction: “Dysfunctions” induced by Roux-en-Y gastric bypass surgery are concomitant with metabolic improvement independent of weight loss




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Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis




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Expert opinion—management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors




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Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea




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Pomalidomide, dexamethasone, and daratumumab in relapsed refractory multiple myeloma after lenalidomide treatment




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SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia




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Leukemia




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Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke




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Noncanonical amino acids on display




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Mining bacteria for biosensors




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Get The Best Minds on Board, Hindustan Times

Years ago, working in the archives in New Delhi, I came across a brief, handwritten, letter from Jawaharlal Nehru to C. Rajagopalachari. It was dated 30th July 1947, and it read: ‘My dear Rajaji, This is to remind you that you have to approach Shanmukham Chetty—this must be done soon. I have seen Ambedkar and [...]




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Changing trends of ocular trauma in the time of COVID-19 pandemic