pro Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3817-3836DOI: 10.1039/D4MD00477A, Research ArticleMaha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa MatboliZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3695-3703DOI: 10.1039/D4MD00546E, Research ArticleMiyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke DemizuA novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3912-3912DOI: 10.1039/D4MD90040E, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex JosephThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Anticancer potential of copper(I) complexes based on isopropyl ester derivatives of bis(pyrazol-1-yl)acetate ligands By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00610K, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maura Pellei, Carlo Santini, Miriam Caviglia, Jo' Del Gobbo, Chiara Battocchio, Carlo Meneghini, Simone Amatori, Chiara Donati, Eleonora Zampieri, Valentina Gandin, Cristina MarzanoIn this paper, the isopropyl ester derivatives LOiPr and L2OiPr of bis(pyrazol-1-yl)acetic acid and bis(3,5-dimethyl-pyrazol-1-yl)acetic acid were used as chelators for the preparation of the new Cu(I) phosphane complexes 1-4....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Supreme Court stays order for CBI probe into sexual assault of minor in Chennai By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:07:47 +0530 Calls for a list of five to seven direct recruit IPS officers, including three women, who hail from other States but are now serving in Tamil Nadu cadre Full Article Tamil Nadu
pro Tamil Nadu CM Stalin to launch Phase II of nutritional intervention programme for malnourished children, mothers By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:23:48 +0530 Mothers of over 76,700 babies in the age group of zero to six months, identified as malnourished, would be covered under Phase II of the programme Full Article Tamil Nadu
pro CM Stalin inaugurates 27 new projects at temples across T.N. By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:23:55 +0530 Full Article Tamil Nadu
pro Godrej Industries Q2 net profit surges over three fold to ₹288 crore By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:47:28 +0530 Full Article Business
pro SKDRDP provides desks and benches worth ₹2.75 crore to 507 government primary schools in four districts of Karnataka By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:49:14 +0530 Rajya Sabha MP Veerendra Heggade urges parents to get their wards admitted to government schools as they now have better facilities Full Article Mangaluru
pro New road proposed from IIT-Tirupati campus to Rachagunneri By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:18:24 +0530 Rachagunneri is home to the massive 400/220/132kV electrical substation and also a private steel plant Full Article Andhra Pradesh
pro Andhra Pradesh govt. reaffirms commitment to ‘irrigating every acre of farmland’ in State through river-interlinking projects By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:43:13 +0530 Full Article Andhra Pradesh
pro Varun Hospitality announces eco-friendly mixed-use project to replace The Gateway Hotel in Visakhapatnam By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:28:31 +0530 Full Article Andhra Pradesh
pro Supreme Court sets pan-India guidelines against ‘bulldozer justice,’ calls demolitions without due process unconstitutional By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 11:31:53 +0530 The Apex court maintains that these guidelines do not apply in cases of unauthorized public land construction or where demolition is mandated by a court ruling Full Article News
pro Karnataka Chief Minister Siddaramaiah says no proposal to ease night traffic ban through Bandipur By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:45:12 +0530 Deputy Chief Minister D.K. Shivakumar had stated, in Wayanad in Kerala, that the government would take all possible measures to lift night traffic ban through Bandipur, which had riled wildlife conservationists in Karnataka Full Article Karnataka
pro Karnataka to roll out e-khatas for all properties in GPs, ULBs to avoid fictitious transactions By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:13:49 +0530 Full Article Karnataka
pro SoftBank swings to profit of $7.7 billion for September quarter on back of strong listings By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 09:49:56 +0530 Vision Funds (SVF1 and SVF2) sold investments totalling $1.85 billion for the six-month period ended September 30 Full Article Companies
pro Delhi HC sets aside Centre’s order cancelling U.S.-based professor’s OCI card By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:10:09 +0530 On the govt.’s allegation of his being involved in “anti-India activities”, the court says the notice lacks specific details or evidence supporting these claims Full Article Delhi
pro U.T. seeks Centre’s nod to implement Smart Meter Project with post-paid plan option By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:27:15 +0530 There is stiff resistance from various quarters for the pre-paid Smart Meter Project. It will be difficult to introduce the prepaid functionality at the beginning stages of the implementation, says Minister for Home A. Namassivayam in his memorandum submitted to Union Minister for Power Manohar Lal Khattar Full Article Puducherry
pro Gokaldas Exports posts 19% growth in Q2 net profit By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:28:34 +0530 Full Article Business
pro Pro Kabaddi League: Gujarat Giants return to winning ways with big win over Bengal Warriorz By www.thehindu.com Published On :: Thu, 14 Nov 2024 06:39:17 +0530 In the second match of the night, Haryana Steelers moved to the top of the table and extended their winning run to four games after defeating the Patna Pirates 37-32 Full Article Sport
pro Villagers oppose proposal for quarry near Sathanur dam at a public hearing By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:59:03 +0530 Tiruvannamalai Collector D. Bhaskara Pandian chaired the hearing organised by the TNPCB on Wednesday. The black granite quarry is proposed to be set up on about 8.46 hectares of government land in Sathanur Full Article Tamil Nadu
pro Unorganised workers federation protests New Labour Codes with demonstration By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:04:19 +0530 Full Article Tiruchirapalli
pro UPPSC aspirants protest continues for third day over exam format By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:35:28 +0530 The job aspirants protest multiple shifts and score normalisation in exams, demanding a fair and unified testing process Full Article Uttar Pradesh
pro Tambaram Corporation begins population survey and area mapping for improved coverage of UPHCs By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:18:44 +0530 Full Article Chennai
pro ED initiates restitution of properties of Heera Group of Companies’ investors By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:50:44 +0530 Full Article Telangana
pro Two men arrested for producing forged demand draft By www.thehindu.com Published On :: Thu, 14 Nov 2024 00:00:36 +0530 Full Article Chennai
pro Telangana’s Congress government is busy implementing programmes without thought By www.thehindu.com Published On :: Thu, 14 Nov 2024 00:40:52 +0530 There is a wide gap between planning and implementation. Full Article Comment
pro L-G approves proposal to deploy former bus marshals on anti-pollution duties By www.thehindu.com Published On :: Thu, 14 Nov 2024 01:08:11 +0530 Full Article Delhi
pro ED files Prosecution Complaint against Jaffer Sadiq before Additional CBI Court By www.thehindu.com Published On :: Thu, 14 Nov 2024 01:59:57 +0530 A release said 20 persons had been arraigned as accused in the case, and Jaffer Sadiq was identified as the mastermind Full Article Tamil Nadu
pro Catering services should only be provided by those having trade licence, says association By www.thehindu.com Published On :: Thu, 14 Nov 2024 07:00:00 +0530 Full Article Mangaluru
pro Lanthanum-doped nickel-based composite metal oxide catalyst for hydrogenation of isophthalonitrile to produce meta-xylenediamine By pubs.rsc.org Published On :: Catal. Sci. Technol., 2024, Advance ArticleDOI: 10.1039/D4CY00802B, PaperHeng Shao, Jing Guo, Rulong Li, Dekun Ji, Long Huang, Haibin ChuLanthanum-doped nickel-based composite metal oxide catalysts exhibited excellent activity in IPN hydrogenation reactions with remarkable stability in fixed-bed reactors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Centre approves widening of Rajahmundry-Anakapalli and Rayachoti-Kadapa national highways to six lanes, says MP By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:40:27 +0530 Full Article Visakhapatnam
pro There is an urgent need to build metro rail project in Visakhapatnam, say local MLAs in the State Assembly By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:53:57 +0530 People have been facing severe traffic problems in the and there is a need for rapid transport system like metro rail, says Gajuwaka MLA Full Article Visakhapatnam
pro Jana Sena Party corporator alleges neglect of crematorium facelift, stages protest By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:10:51 +0530 Full Article Visakhapatnam
pro VSEA expresses concern over iron ore supply to VSP due to proposed ArcelorMittal & Nippon Steel plant in Anakapalli By www.thehindu.com Published On :: Thu, 14 Nov 2024 00:51:25 +0530 We have appealed to the governments to take a note of RINL’s iron ore issue before finalising anything on Mittal’s steel plant in Anakapalli, says association general secretary Full Article Visakhapatnam
pro Gokaldas Exports net profit up by 19%, at ₹28.2 crore for Q2FY25 By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 14:50:23 +0530 The total income stood at ₹941.8 crore, reflecting an 85 per cent increase from ₹509 crore and the EBITDA margin for Q2 was 8.7 percent Full Article Companies
pro Favourable winter, kharif produce may temper inflation surge, says QuantEco By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 15:06:40 +0530 October’s inflation peak may soon be followed by a moderation, supported by a favourable winter season and increased availability of kharif produce Full Article Economy
pro EIH hopes to complete 20 properties by 2029 By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 18:03:40 +0530 EIH reported around 41 per cent surge in consolidated net profit to ₹132.70 crore for Q2FY25 Full Article Companies
pro Torrent Power reports 8.5% decline in Q2 net profit By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 18:39:43 +0530 Its revenue from operations rose 3 per cent to ₹7,176 crore in the second quarter Full Article Companies
pro Kalyan Jewellers posts ₹308 crore profit in H1 By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 18:53:46 +0530 Revenue rises to ₹11,601 crore during H1 Full Article Companies
pro R K Swamy’s Q2 profit decline, announces new customer facility launch By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 19:49:30 +0530 Shekar Swamy, Group CEO, said that despite the dip in revenue, the company’s new business pipeline remains strong Full Article Companies
pro Is boosting revenue via higher property taxes viable? By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 21:06:52 +0530 In India, there are hordes of unauthorised residential units, and levying even a low tax on these may be politically challenging Full Article Opinion
pro Google grants $1 million to Indian non-profit AI startup Karya By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:02:38 +0530 The startup has helped over 50,000 people in rural India in the past two years by offering them data annotation jobs Full Article Technology
pro Macquarie sees bright prospects for India’s power utilities and lenders: Buy calls for PFC, REC, NTPC, PGCIL By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 09:08:54 +0530 With strong balance sheets, PFC, REC, NTPC, and PGCIL are well-prepared to increase capital expenditure Full Article Markets
pro Sterlite Technologies secures ₹2,600 crore BharatNet project in Jammu and Kashmir By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 10:57:08 +0530 Sterlite Technologies to implement an automation-led fibre deployment approach, utilising drone surveys, GIS mapping, and AI-led network design Full Article Stocks
pro Anupamaa producer Rajan Shahi breaks silence over Rupali Ganguly's dispute with stepdaughter Esha Verma: 'You have...' By www.dnaindia.com Published On :: Thu, 14 Nov 2024 00:20:20 GMT Anupamaa producer Rajan Shahi has supported Rupali Ganguly after the actress slapped her stepdaughter Esha Verma with a legal notice, seeking Rs 50 crore in damages. Full Article Entertainment Television
pro Stars Buying Property After Property! By www.rediff.com Published On :: Wed, 13 Nov 2024 09:29:48 +0530 'Just this year alone, close to 40 major transactions involving Bollywood stars have been recorded.' Full Article
pro VideoProc Converter AI Review By www.infopackets.com Published On :: Mon, 12 Aug 2024 16:12:59 +0000 What's one of the best one-stop video/image quality enhancement and editing software available for Windows? Answer: Digiarty's VideoProc Converter AI! From the makers of WinX DVD Ripper and WinX Video Converter comes VideoProc Converter: a multi-award winning software program that is a one-stop video/image processing program that allows you to restore and enhance video image quality in 1 click, convert video/audio, rip DVDs, edit video, download videos, video to GIF maker ... plus much more! The latest version of VideoProc Converter AI includes the ability to upscale old pictures and video ... (view more) Full Article
pro Infopackets to Launch YouTube Tech Support Pilot Program By www.infopackets.com Published On :: Fri, 27 Sep 2024 20:44:27 +0000 Dear Infopackets Readers, I would like to introduce the launch of an exciting, new video-based tech support Q ... (view more) Full Article
pro Broadband Subsidy Program Ends But Debate Continues By www.infopackets.com Published On :: Wed, 09 Oct 2024 17:17:27 +0000 Four months after the end of a subsidy program for home broadband, individual states are figuring out if and how they can expand access. Meanwhile the debate over the value and impact of the Affordable Connectivity Program (ACP) continues to rage. The program launched in 2021 as part of a wider infrastructure package. It was available to households earning up to double the federal poverty level or with somebody in a government assistance program. Under the program, households would get a government-funded discount of up to $30 a month on broadband services and a one-off discount of $100 for a ... (view more) Full Article