ty Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3711-3727DOI: 10.1039/D4MD00584H, Research ArticleSara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-DiasA series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ty Fexinidazole optimization: enhancing anti-leishmanial profile, metabolic stability and hERG safety By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3837-3852DOI: 10.1039/D4MD00426D, Research ArticleAbdrrahman Shemsu Surur, Chin Fung Chan, Frieda-Marie Bartz, Iris L. K. Wong, Van T. D. Nguyen, Lukas Schulig, Andreas Link, Tak Hang Chan, Larry M. C. Chow, Patrick J. BednarskiStructure-guided optimization of fexinidazole led to analog (S)-51, a promising lead compound with superior activity, improved metabolic stability, and enhanced hERG safetyThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ty IIT Madras to conduct two-day summit on extended reality By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:19:23 +0530 The aim is to develop academic partnership programmes to boost research in XR or extended reality Full Article Chennai
ty IIT-M students develop robot for O.P. Jindal university’s Constitution Museum By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:44:27 +0530 It is trained to respond to questions from visitors in Hindi and English, IIT-M professor says Full Article Tamil Nadu
ty Delhi’s air quality turns ‘severe’ for first time this season: CPCB By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:52:21 +0530 According to Central Pollution Control Board data, Delhi’s air quality reaches ‘severe’ levels with AQI of 418 Full Article Delhi
ty Sensex, Nifty hit a five-month low By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:11:22 +0530 Fifth straight losing session at the bourses; shares in the midcap, small cap segments plunged harder than large companies’ stocks in what some called ‘correction mode’ Full Article Business
ty Varun Hospitality announces eco-friendly mixed-use project to replace The Gateway Hotel in Visakhapatnam By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:28:31 +0530 Full Article Andhra Pradesh
ty Doctor stabbed at Kalaignar Centenary Super Speciality Hospital in Chennai; one arrested By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:24:15 +0530 The oncologist who was attacked has been identified as Balaji Jagannath. He has been admitted in the ICU, and his condition is said to be critical Full Article Chennai
ty Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36352-36369DOI: 10.1039/D4RA07074G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mingxing Qian, Yuanjian Xu, Hong-Jin Shu, Zi-Wei Chen, Lei Wang, Charles F. Zorumski, Alex S. Evers, Steven Mennerick, Douglas F. CoveyPhotoaffinity labels (PALs) for sulfated steroid binding sites on GABAA and NMDA receptors. The PALs have varying profiles of positive and negative modulatory (PAM and NAM) actions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ty Synthesis of MOF-supported Pt catalyst with high electrochemical oxidation activity for methanol oxidation By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36370-36377DOI: 10.1039/D4RA06393G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Merve Akin, Hatice Kars, Muhammed Bekmezci, Aysenur Aygun, Mert Gul, Guray Kaya, Fatih SenIn this study, Pt and Pt@Ti-MOF NPs catalysts were synthesized by chemical reduction method. Ti-MOF structure was synthesized using the solvothermal method, and the effect of Ti-MOF on methanol oxidation was investigated.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ty Marakumbi atrocity case: 99 persons granted bail by High Court Dharwad Bench By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:34:18 +0530 Full Article Karnataka
ty Kalaburagi city police arrests 30 vehicle lifters, recovers 105 motorbikes By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:44:13 +0530 Full Article Karnataka
ty Why US chess champ Levon Aronian is connecting with the Armenian community in Chennai By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:54:02 +0530 Chess champion Levon Aronian, who competed in Chennai Grand Masters recently, on future Indian chess superstars Full Article Sport
ty Allison Transmission to double Chennai facility with $100 mn+ investment amid rising global demand By www.thehindubusinessline.com Published On :: Thu, 14 Nov 2024 07:33:39 +0530 The expansion aims to double the facility’s size, creating 167 new jobs, and enhance production capacity for automatic transmissions in response to growing global demand Full Article Companies
ty Daylight assault on doctor inside Chennai hospital leaves medical fraternity in shock By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:20:29 +0530 The attacker, Vignesh, was reportedly frustrated over the treatment given to his mother, who was diagnosed with Hodgkin’s Lymphoma in an advanced stage Full Article Chennai
ty Residents raise concerns over water quality and odour from Vellalore dump yard By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:22:04 +0530 Full Article Coimbatore
ty Indian gaming sector urged to embrace diversity beyond performative actions By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:43:04 +0530 ‘Inclusion of female and LGBTQIA+ characters remains limited, underscoring a lack of representation’ Full Article Hyderabad
ty The CKM syndrome as the price of modernity By www.thehindu.com Published On :: Thu, 14 Nov 2024 00:08:00 +0530 An unhealthy lifestyle and the influence of globalisation are silently shaping a major global health issue Full Article Comment
ty Parthiv Patel gets dual responsibility with Gujarat Titans: batting and assistant coach By www.thehindu.com Published On :: Thu, 14 Nov 2024 03:51:09 +0530 Parthiv Patel will perform the dual role in the support staff led by head coach Ashish Nehra Full Article Cricket
ty Fifty years ago | Tamil Nadu omnibus tax increase held valid By www.thehindu.com Published On :: Thu, 14 Nov 2024 04:35:00 +0530 Full Article Archives
ty Thiruvalluvar University in Vellore seeks contributions from public for its Academic Development Fund By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:03:27 +0530 Full Article Tamil Nadu
ty No roadmap yet for better traffic signage system in Kozhikode city By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:33:12 +0530 Emergency signboards and lane markings near roundabouts have not yet been introduced to streamline the traffic management Full Article Kerala
ty Policeman dies of heart attack while on duty By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:58:29 +0530 Full Article Chennai
ty Police arrest man for employing, abusing 11-year-old domestic help in Noida society By www.thehindu.com Published On :: Thu, 14 Nov 2024 00:58:38 +0530 Full Article Delhi
ty Delhi breathes its worst quality air of the season; smog blanket leads to disruptions at airport By www.thehindu.com Published On :: Thu, 14 Nov 2024 01:07:42 +0530 Official data place Capital on top of India’s most polluted cities list; no reprieve likely today; BJP takes on AAP govt. over the issue, demands closure of primary schools; keeping close watch on the situation, says Centre’s air quality monitoring panel Full Article Delhi
ty Demanding security, Tamil Nadu government doctors begin indefinite strike By www.thehindu.com Published On :: Thu, 14 Nov 2024 01:18:08 +0530 Federation of Government Doctors’ Association will decide on the next course of action at an executive committee meeting to be held on November 17, 2024. Full Article Tamil Nadu
ty Republicans complete power takeover with House majority By www.thehindu.com Published On :: Thu, 14 Nov 2024 05:26:43 +0530 After more than a week of vote counting Republicans party had reached the 218 seats needed to retain their majority in the 435-seat lower chamber, having already seized the Senate from the Democrats. Full Article U.S. Elections
ty India’s tea, sugar exports raise sustainability concerns at home | Explained By www.thehindu.com Published On :: Thu, 14 Nov 2024 05:30:00 +0530 Exports help strengthen India’s economy by increasing revenue but the rapid surge in exports poses multiple challenges to the sustainability of production, processing, and distribution systems Full Article Environment
ty In Beed, Independent candidates on strong footing against party nominees By www.thehindu.com Published On :: Thu, 14 Nov 2024 05:43:54 +0530 Candidates who rebelled against party diktat stand out with strong support at the ground level and also have high chances of winning the seat Full Article Maharashtra Assembly
ty Jana Sena Party corporator alleges neglect of crematorium facelift, stages protest By www.thehindu.com Published On :: Wed, 13 Nov 2024 22:10:51 +0530 Full Article Visakhapatnam
ty Stress on integrity at workplace By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:18:36 +0530 Full Article Madurai
ty Financial viability of Discoms a matter of concern: Power Minister By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 13:04:54 +0530 The Minister noted that the Average Cost of Supply (ACS)-Average Realizable Revenue (ARR) gap has improved to ₹0.21 per kilowatt-hour (kWh) in FY24 Full Article Economy
ty Equity markets slump as retail inflation soars, foreign fund outflows continue By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 17:40:21 +0530 Full Article Video
ty Own revenue sources of majority of the Municipal Corporations not adequate for meeting RevEx: RBI report By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 18:49:28 +0530 The revenue receipts of MCs, including own tax revenue, own non-tax revenue, and transfers, amounted to 0.6 per cent of GDP in 2023-24 (the same as in 2019-20). MCs are are the third tier of the government in large urban areas Full Article Economy
ty R K Swamy’s Q2 profit decline, announces new customer facility launch By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 19:49:30 +0530 Shekar Swamy, Group CEO, said that despite the dip in revenue, the company’s new business pipeline remains strong Full Article Companies
ty Is boosting revenue via higher property taxes viable? By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 21:06:52 +0530 In India, there are hordes of unauthorised residential units, and levying even a low tax on these may be politically challenging Full Article Opinion
ty How are Indian investors shaping the real estate boom at Expo City Dubai? By www.thehindubusinessline.com Published On :: Thu, 14 Nov 2024 06:00:00 +0530 Indian investors are among the top three buyers of residential and commercial real estate in Expo City, says Ahmed Al Khatib, Chief Development and Delivery Officer Expo City Dubai. Full Article Podcast
ty Day Trading Guide for November 14, 2024: Intraday supports, resistances for Nifty50 stocks By www.thehindubusinessline.com Published On :: Thu, 14 Nov 2024 06:30:00 +0530 Here are the intraday supports and resistances for widely traded stocks such as Reliance Industries, ITC, ONGC, Infosys, HDFC Bank, TCS, and SBI Full Article Day trading guide
ty Nifty slumps 10% from peak, Bank Nifty weekly contracts bid adieu By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 20:43:49 +0530 Inflation, firm dollar add to volatility amid FPI selling spree Full Article Markets
ty November 14, 1984, Forty Years Ago: Election Dates Out By indianexpress.com Published On :: Wed, 13 Nov 2024 21:30:20 +0000 Full Article 40 Years Ago Opinion
ty CoP’s hasty decision on carbon credits could do more harm than good By indianexpress.com Published On :: Wed, 13 Nov 2024 22:43:53 +0000 Full Article Editorials Opinion
ty Delhi's air quality worst in country, turns 'severe' By www.rediff.com Published On :: Thu, 14 Nov 2024 01:49:54 +0530 The city's 24-hour Air Quality Index, recorded at 4 pm every day, stood at 418, up from 334 the previous day, and it may trigger stringent restrictions under the third stage of the graded response action plan to mitigate hazardous conditions. Full Article
ty World Diabetes Day 2024: Types, causes, precaution to avoid this chronic disease By www.dnaindia.com Published On :: Thu, 14 Nov 2024 00:39:18 GMT While some types of diabetes are manageable with medications and lifestyle adjustments, others can lead to long-term health issues. Full Article Health
ty Stars Buying Property After Property! By www.rediff.com Published On :: Wed, 13 Nov 2024 09:29:48 +0530 'Just this year alone, close to 40 major transactions involving Bollywood stars have been recorded.' Full Article
ty Google Reveals Election Security Efforts By www.infopackets.com Published On :: Fri, 06 Sep 2024 19:23:33 +0000 Google has revealed a series of measures aimed to better inform US voters while reducing the risk of malicious misinformation. It includes restrictions on its AI tools and better protection against cyber attacks for election and campaign officials. The measures broadly break down into three categories. The first is better information for users who are trying to find out more about elections. For example, users who search YouTube for the name of an election candidate will get an information panel detailing official website and video channel links for the candidate. (Source: engadget.com ) ... (view more) Full Article
ty AI Songs Earn $12 Million in Royalty Scam By www.infopackets.com Published On :: Fri, 13 Sep 2024 17:40:02 +0000 A man who earned $12 million in royalties after "writing" hundreds of thousands of songs has been charged with fraud. Michael Smith allegedly created the songs with artificial intelligence, then used bots to "listen" to the music on streaming services to generated revenue. The case against Smith is not that the music itself was "not real" but rather that he was falsely claiming credit for listeners. Prosecutors say that not only did he steal money from the streaming sites, but that legitimate songwriters missed out. That's because some streaming sites divide a fixed ... (view more) Full Article
ty Win10 End-of-Life has Major Security Implications By www.infopackets.com Published On :: Fri, 25 Oct 2024 17:44:03 +0000 With less than a year to go, Microsoft is sticking to its vow to stop supporting Windows 10. Analysts remain unconvinced given it remains the most used version of Windows. Officially, October 14, 2025 will be the end of life date for the system. Although it will still work, Microsoft will no longer offer security updates for Windows as standard. Instead, users will have the option to pay for extended security support. (Source: microsoft.com ) 10 Year Life Cycle In principle, this is perfectly normal. Next year is 10 years after Windows 10 was first released, and that's the normal ... (view more) Full Article
ty Android 15 Boosts Security, Theft Detection Lock By www.infopackets.com Published On :: Mon, 28 Oct 2024 20:17:20 +0000 Google has announced a range of security and privacy boosts for Android 15. It's also rolling out a key feature called Theft Detection Lock to older handsets. The new version of Android is coming to Google's own Pixel handsets almost immediately and then will go out to other manufacturers. The release date and which handsets it works on depends on the manufacturer. Theft Detection Lock Explained Unlike some previous new versions of Android which have often seemed more focused on appearance and style, the focus this time is much more practical. The most high-profile change is Theft Detection ... (view more) Full Article
ty Authority in the Church By www.ancientfaith.com Published On :: 2015-01-26T03:22:54+00:00 Fr. Andrew Damick joins Fr. Barnabas to discuss the issue of authority in the Orthodox Church. How far does it extend? Who is the final authority? Full Article
ty African Americans and Orthodox Christianity By www.ancientfaith.com Published On :: 2015-10-26T02:45:59+00:00 Fr. Moses Berry joins Fr. Barnabas to discuss his journey to Orthodoxy as the great grandson of a slave. What does Orthodox Christianity offer to the African American today? Learn more about Fr. Moses and a documentary film being produced called Hard Promise to Keep. Full Article