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Immune cells blast infections and cancer with protein ‘bombs’

Cells use complex containers to launch toxic chemicals at their victims




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Julia Aguado Fernandez of Valencia battles for the ball with Laura Frey of BSC Young Boys

ZURICH, SWITZERLAND - MAY 10: Julia Aguado Fernandez of Valencia battles for the ball with Laura Frey of Young Boys during the Blue Stars FIFA Youth Cup 2018 Women's final match between Valencia Ladies and Young Boys Ladies at Sportanlage Buchler on May 10, 2018 in Zurich, Switzerland. (Photo by Alexander Hassenstein - FIFA/FIFA via Getty Images)




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From ambulances and education to pizza and asparagus




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Baresi: Real football fans understand the importance of defenders

Baresi: I’m lucky to have played at three World Cups




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#WorldCupAtHome | France v Croatia (France 1998)




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Vicky Kaushal: I have experienced sleep paralysis

Actor Vicky Kaushal feels the phenomenon of sleep paralysis is scary. On Instagram, Vicky recently conducted an interactive session with fans. When a user asked him if he has ever seen a ghost in real life, Vicky opened up on the subject of sleep paralysis.

"I have experienced sleep paralysis couple of times. It's damn scary," he wrote. Sleep paralysis is a medical condition where a person, on waking up from sleep, experiences temporary inability to move or speak.

The actor also shared that he is scared of watching horror films. Incidentally, he recently starred in the horror film, "Bhoot Part One: The Haunted Ship". The film performed below expectations.

Vicky will next be seen in Shoojit Sircar's "Sardar Udham Singh". He has also signed Meghna Gulzar's film biopic of Field Marshal Sam Manekshaw. He will be essaying the title roles in both films.

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Offline house party busted by cops at Anita Raaj's Bandra residence?

Neighbours of yesteryear actor Anita Raaj and her husband Sunil Hingorani have alleged that the couple had been entertaining guests at their Pali Hill home on Monday despite the lockdown. High drama ensued at the posh Bandra address when cops landed at the actor's doorstep following the neighbours' complaint.

A source says, "Ever since the lockdown was announced, the society has barred entry for outsiders. So, the neighbours were surprised at the steady stream of visitors at her flat and expressed concern about the threat it posed to their health. On Monday, when it was noticed that they were entertaining guests, the local cops were informed."

The situation apparently took a turn for the worse after the cops left the premises. In a video that is in possession of mid-day, it can be seen that Raaj and her husband had a heated argument with the security guard in the lobby. "They wanted to know who had complained about them to the cops. At one point, they asked the guard if he had informed the neighbours about the visitors," adds the source.

When mid-day reached out to Raaj, she offered a different version of events. "Since my husband is a doctor, one of his friends had come home for a medical emergency. His wife came with him for assistance. My husband couldn't refuse him on humanitarian grounds. After checking the situation, the cops apologised for the false complaint that was lodged with them and left immediately."

The actor, best remembered for films like Prem Geet (1981) and Naukar Biwi Ka (1983), and currently seen on television in Chhoti Sardaarni, asserted that she would not compromise the safety of others. "I won't behave irrationally by hosting a party in the current scenario."

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Raid 2 in the works; Ajay Devgn's film to be made into a multi-film franchise?

If you liked Ajay Devgn's 2018 mystery thriller Raid, then you will love this bit of news! It's being reported that Devgn's film will soon get a sequel, as the actor and producer Bhushan Kumar are already said to be working on it. Plus, according to a report, Raid will be turned into a multi-film franchise. Excited yet?

A source close to the development informed Mumbai Mirror, "The franchise seeks to bring into the public eye heroes who work closely with intelligence agencies to track white-collar crimes. To this day, nobody knows the identity of the officer on whom Ajay's Amay was modelled. Raid 2 will also be a tribute to men who don’t wear the uniform."

Bhushan Kumar, who produced the first film, told the publication, "It will be a huge multi-film franchise and Ajay Ji and I, along with Kumar Mangat ji, are looking to take Raid forward. The script of Part 2 is being developed. Since the original was a much-loved film, the sequel is a huge responsibility. After the super success of Tanhaji: The Unsung Warrior, there's a lot of pressure on this collaboration to live up to the expectation. We have always aimed at creating high concept films."

Raid, directed by Raj Kumar Gupta, starred Ajay Devgn an IRS officer, Amay Patnaik. While Devgn and Bhushan Kumar are already collaborating on Bhuj: The Pride Of India, news of them reuniting for the Raid series is much welcome for fans of the film!

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Amitabh Bachchan shares throwback picture of himself, says 'the age of innocence is over'

Amitabh Bachchan's social media feed is filled with moments and memories from his life. The superstar is known to dig out old photographs of himself and Bachchan family. His social media account is a treat for all the Bollywood buffs and especially people who are their fans and admirers. With the country undergoing lockdown due to coronavirus, the actor has taken up the task to fill smiles in this gloomy times through his adorable pictures.

Continuing the trend, Amitabh Bachchan posted another throwback picture of himself on his Instagram account. This picture is a collage of four images from his earlier years. The first picture is of the superstar in his youthful days, while the other three are just one picture, repeated thrice which shows off his "angry young man" look. Sharing the picture, the Piku actor wrote, "The age of innocence is over (sic)."

 
 
 
View this post on Instagram

The age of innocence is over ..

A post shared by Amitabh Bachchan (@amitabhbachchan) onApr 22, 2020 at 12:48pm PDT

Earlier, the superstar had shared a throwback picture of the premiere of his cult classic film Sholay. In the picture, he can be seen along with his co-star and wife Jaya Bachchan and Ramesh Sippy. "At the Premiere of SHOLAY .. 15th August 1975, at the Minerva .. Ma, Babuji, Jaya and a bow tied moi .. how pretty Jaya looks .. This was the 35 mm print at the Premiere .. the 70mm Stereo sound print , first time in India was stuck in Customs.. but after the Premiere got over by midnight, we got news that the 70mm print was out of Customs .. we told Ramesh ji to get it to the Minerva .. it came .. the first Indian film on 70mm Stereo .. and I sat on the floor of the Balcony with Vinod Khanna and finished seeing this amazing result till 3 in the morning (sic)", he captioned it.

 

 
 
 
View this post on Instagram

A post shared by Amitabh Bachchan (@amitabhbachchan) onApr 17, 2020 at 3:26am PDT

This was followed by a never-seen-before picture of himself from his younger days. "My very first photoshoot for a film magazine after joining the Industry in 1969 .. it was for the ‘Star & Style’ the only other prominent film mag., along with Filmfare at the time .. I was pushed and goaded into - a most reticent reluctant and very self-conscious shy me - by the most famed and feared journalist of the times - Devayani Chaubal .. obviously there was no ‘star’ or ‘style’ in the project .. but Devyani thought so .. a strong-minded lady, ever dressed in a shining white sari .. always !!! (sic)", he captioned it.

On the work front, Amitabh Bachchan will next be seen in Chehre alongside Emraan Hashmi, and Ayan Mukerji's Brahmastra with Alia Bhatt and Ranbir Kapoor. He recently wrapped up shooting for Gulabo Sitabo where he will be seen alongside Ayushmann Khurrana for the first time.

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Raveena Tandon's appeal: Help family of driver lynched in Palghar brutality

Actress Raveena Tandon has appealed all to extend help to the family of deceased Palghar lynching victim Nilesh Telwade. Sharing a website where one can donate, Raveena Tandon tweeted: "A fundraiser for the 29 yr old driver who was lynched along with Hindu sadhus. He leaves behind two little girls, please do your bit and help this family."

Twenty-nine-year-old Nilesh, a driver by profession, was lynched along with two sadhus by a mob of over 200 people in Maharashtra's Palghar last week. The brutal incident occurred while they were travelling from Nashik to Surat with some relief materials.

Suspecting them to be thieves, the crowd started questioning them, abused and then assaulted them brutally with sticks, rods and stones. Nilesh Telwade's untimely death has left his family including his wife and two little daughters in a helpless condition.

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This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever




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Shilpa Shetty and hubby show off Punjabi dance moves

Actress Shilpa Shetty and her husband Raj Kundra showed off some Punjabi dance moves in their new video. The couple are killing time during lockdown with some happy dancing, going by their latest TikTok video that has them dancing to a catchy tune. "If you're happy and you know it.. just Balle Balle," read the caption.

Dancing isn't their only fitness secret. Shilpa recently opened up about the workout schedule she and her family follow.

"I had shared a little exercise-fun with Viaan (Shilpa's son) a few days ago, and I was asked for the entire workout video. Well, I don't have the entire workout captured, but sharing what I found from my archives. I truly believe that the family that eats, prays and works out together... stays together!" Shilpa wrote, sharing a glimpse of her workout session with Raj, and their son Viaan.

"Oftentimes when @rajkundra9 and I workout in the mornings, we get Viaan to join us too. We do understand that if it's not fun for him, he's not going to enjoy the process. So, while we roped in some abs workout for ourselves, we got him to hop, slide, and jump around," she added in the social media post.

 
 
 
View this post on Instagram

I had shared a little exercise-fun with Viaan a few days ago, and I was asked for the entire workout video. Well, I don’t have the entire workout captured, but sharing what I found from my archives. I truly believe that the family that eats, prays and works out together... stays together! Oftentimes when @rajkundra9 and I workout in the mornings, we get Viaan to join us too. We do understand that if it's not fun for him, he's not going to enjoy the process. So, while we roped in some abs workout for ourselves, we got him to hop, slide, and jump around. Our workout helps us build & strengthen the abdominal muscles, while it also helps improve the mind-body coordination and enhances speed & endurance capacity. Viaan, on the other hand, was just happy to be jumping around and using up some of that pent up energy. A morning well-spent, this was! I hope you all are staying home and staying fit too! . @thevinodchanna . . . . #SwasthRahoMastRaho #GetFit2020 #MondayMotivation #FitIndia #FitIndiaMovement #homefitness #homeworkouts #fitness #COVID19

A post shared by Shilpa Shetty Kundra (@theshilpashetty) onApr 19, 2020 at 10:30pm PDT

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Five instances when Kareena Kapoor Khan showcased her wit and humour on Instagram

Is there anything Kareena Kapoor Khan can't do? She's a talented actor, a style icon, an amazing mum to little Taimur, and just about everything else that makes her uniquely Bebo. She may have joined the Instagram party late, but by now we know that Bebo is the life of any party she joins, even if she does so fashionably late!

Here are five instances on Instagram when Kareena Kapoor showcased her tremendous wit and humour!

When Bebo as a baby shared a gem about social distancing

First of all, how utterly adorable is this photo of a tiny little Kareena Kapoor? She used this throwback photo to talk about social distancing and show us how important it is in the deadly times of corona. Bebo captioned this image, "Me... when someone tries to shake my hand these days!
#StayHome #StaySafe #SocialDistancing"

When she modelled a pasta necklace made by Tim

Even a necklace made from pasta looks good on Bebo, proving that the Good Newwz actor can wear anything and look like a million bucks. This necklace was made by her dear little boy Taimur, and Kareena wrote alongside this picture, "Pasta la vista. Handmade Jewellery by Taimur Ali Khan #QuaranTimDiaries" #QuaranTimDiaries... now isn't that creative?

When Kareena stared in shock at the zit on her face

Yes, Bebo also falls victim to unwarranted and unwanted zits sometimes. But does she fret? No, the queen never frets! Instead, she makes fun of it by writing, "Meanwhile... I just sat there staring in wonder of what was being created. PS: The zit on my face didn't get the memo of no personal visits and social distancing... #HugeMess"

When she wished Aamir Khan in the funniest way

Kareena Kapoor Khan also found the best way to wish her Laal Singh Chaddha co-star, Aamir Khan, a happy birthday. Sharing a photo of a snoozing and pillow-cuddling Aamir, she wrote, "My fav co-star has to be @_aamirkhan's... pillow!" 

When she wanted to fall in love... or was it fall asleep?

Like us, Kareena, too, is bored sitting at home. And while husband Saif Ali Khan can be seen spending his time reading and lazing around in the grass, Kareena seems to be quite unoccupied in this photo! "Fall i̶n̶ ̶l̶o̶v̶e̶ asleep... #Mess" she captioned this cute picture of her passing time with Saif.

Which of Kareena Kapoor's Instagram photos did you like the most?

On the work front, Kareena was recently seen in Irrfan Khan and Radhika Madan's Angrezi Medium. She will be next Laal Singh Chadha opposite Aamir Khan. The film is a remake of Tom Hanks' Forrest Gump (1994) and is helmed by director Advait Chandan. The movie is slated to hit theatres on Christmas 2020.

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Kanika Kapoor finally breaks silence on her Coronavirus tests, reveals why she was silent

Kanika Kapoor has gone through a lot in the last few weeks. The singer traveled to the UK and was tested Coronavirus positive shortly after her return to India. Not once or twice, but she was tested Coronavirus positive as many as four times. Her family members were constantly with her and they even spoke about it.

However, nothing was heard from the singer. And little did she expect that her tests would also make her the talk of the town and people would even start making memes and opinions on social media. But now, it seems it was time for her to come out of the closet and reveal what kept her silent for so long. And she has! In a long Instagram post, she has finally spoken about her trip to London, her Coronavirus tests, and the long silence.

She wrote- "I know there are several versions of stories out there about me. Some of these seem to be fuelled even more because I have chosen to be silent till now. I stayed quiet not because I am wrong but in-fact being fully aware that there have been misunderstandings and wrong exchanges of information." (sic)

The post contains the minutest of details that will clear all the confusion people have had about her so far. Read it right here:

 
 
 
View this post on Instagram

Stay Home Stay Safe 🙏🏼

A post shared by Kanika Kapoor (@kanik4kapoor) onApr 26, 2020 at 1:50am PDT

In the end, she also asked us to stay home and stay safe. Well, given she has clarified everything; hopefully she should not be the target of memes and trolls now!

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7 years of Aashiqui 2: How Shraddha Kapoor became an overnight star and has been unstoppable ever since!

It has been seven years since Mohit Suri's Aashiqui 2, starring Aditya Roy Kapur and Shraddha Kapoor came out. It made the actress an overnight star and sensation, and her character, Aarohi, still continues to be remembered for her piquancy and innocence, and of course, singing.

Every year, the actress does something special on this day to mark this musical blockbuster's anniversary and this year was no exception. She not only changed her Instagram name to her screen name from the film and upload a new photo from one its stills, but also uploaded a collage of some of the film's scenes to create one beautiful picture.

This is truly an innovative and imaginative way to celebrate your film, don't miss this post:

Shraddha Kapoor is well known for always delivering hits along with a new character and fresh content with every project. Shraddha being a lover of always wanting to try something new has been unstoppable ever since Aashiqui 2.

After Aashiqui 2, taking no breaks, Shraddha was seen in Ek Villain, where the character of being full of life was super fresh. Not forgetting ABCD 2 where Shraddha's dance totally stole hearts. Shraddha showed her versatility factor and the audiences were stunned on how the actress can mould herself in every way possible.

Moulding herself into another new character, Shraddha was seen doing some kicks and punches in Baaghi. The actress has given a carousel of hits and is a roll as the actress chooses quality projects over quantity and this totally sets her apart. Shraddha knows how to treat her fans with the best of characters, where fresh content always hunts Shraddha.

On the work front, Shraddha will be seen in a Luv Ranjan directorial alongside Ranbir Kapoor. The actress is basking in the success of Baaghi 3. Truly we can't wait to see what this fresh pair has brewed for us!

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Acupuncture during IVF may not boost woman's chances of getting pregnant: Study

Acupuncture may not boost chances of IVF success



Undergoing acupuncture treatment during in vitro fertilisation (IVF) might not increase a woman's chances of conceiving, finds a study. The study, however, showed that acupuncture is no better than placebo for improving IVF success.

Acupuncture, a traditional Chinese medicine in which thin needles are inserted into the body, has become a widely used treatment prior to and during IVF.

It showed no significant benefit from IVF when compared with a short course of acupuncture using dummy needles placed away from "true" acupuncture points.

"Our findings do not support acupuncture as an efficacious treatment compared to sham," lead investigator Caroline Smith, Professor at the Western Sydney University in Australia.

For the study, published in the journal JAMA, the team included over 800 Australian and New Zealand women to examine the effects of acupuncture administered prior to and following an embryo transfer (ET).

The participants were given either acupuncture or a sham acupuncture control (a non-insertive needle placed away from the true acupuncture points).

The results showed the rate of live birth was 18.3 per cent among participants who received acupuncture versus 17.8 per cent who received the sham acupuncture control, a non-significant difference.

While a short course of acupuncture may statistically be no better than sham at improving live birth and pregnancy outcomes, a psycho-social benefit from acupuncture was reported by women undergoing IVF, the researchers said.

"Some studies suggest reproductive outcomes maybe improved when acupuncture is compared with no treatment," Smith said.

"Feeling relaxed and reporting relief from stress and women feeling good about themselves is to be welcomed for women as they undergo an IVF cycle," explained co-author Michael Chapman, Professor at the University of New South Wales, Sydney.

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Fighting with spouse may increase chronic pain



People with chronic conditions like arthritis or diabetes may suffer physical repercussions if they get into a fight with their spouse, according to a new study.

The findings, published in the journal Annals of Behavioral Medicine, suggests that in two groups of older individuals -- one group with arthritis and one with diabetes -- the patients who felt more tension with their spouse also reported worse symptoms on those days.

"The findings gave us an insight into how marriage might affect health, which is important for people dealing with chronic conditions like arthritis or diabetes," said co-author Lynn Martire, Professor at Pennsylvania State University in the US.

People with osteoarthritis in their knees who experience greater pain become disabled quicker, and people with diabetes that is not controlled have a greater risk for developing complications, the researcher said.

For the study, the researchers recruited a group of 145 patients with osteoarthritis in the knee and their spouses. The other included 129 patients with Type 2 diabetes and their spouses.

The participants in both groups kept daily diaries about their mood, how severe their symptoms were, and whether their interactions with their spouse were positive or negative. The participants in the arthritis and diabetes groups kept their diaries for 22 and 24 days, respectively.

The researchers found that within both groups of participants, patients were in a worse mood on days when they felt more tension than usual with their spouse, which in turn led to greater pain or severity of symptoms.

The researchers also found that within the group with arthritis, the severity of the patient's pain also had an effect on tensions with their spouse the following day.

When they had greater pain, they were in a worse mood and had greater tension with their partner the next day, the researcher added.





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Depression in male partner may lower pregnancy chances



Among couples being treated for infertility, depression in the male partner was linked to lower pregnancy chances, according to a study.

The study showed that couples in which the male partner had major depression were 60 per cent less likely to conceive and give birth than those in which the male partner did not have major depression.

On the other hand, depression in the female partner was not found to influence the rate of birth.

In addition, intake of a class of antidepressants known as non-selective serotonin reuptake inhibitors (non-SSRIs) was also linked to a higher risk of early pregnancy loss among females being treated for infertility, the study appearing in the journal Fertility and Sterility, noted.

However, SSRIs, another class of antidepressants, were not linked to pregnancy loss. Neither depression in the female partner nor the use of any other class of antidepressant were linked to lower pregnancy rates.

"Our study provides infertility patients and their physicians with new information to consider when making treatment decisions," said Esther Eisenberg, at National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in Maryland, US.

Citing previous studies, the authors noted that 41 per cent of women seeking fertility treatments have symptoms of depression.

Another study of men seeking in-vitro fertilisation (IVF) treatments reported that nearly 50 per cent experienced depression.

For the study, the team analysed data for 1,650 women and 1,608 men to evaluate the potential influence of depression in couples seeking non-IVF treatments.

Among the women, 5.96 per cent were rated as having active major depression, compared to 2.28 per cent of the men.

Women using non-SSRIs were roughly 3.5 times as likely to have a first-trimester pregnancy loss, compared to those not using antidepressants.

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Sex and certain virus can help fight cancer

Turns out, sex and some certain virus can provide aid to fight against cancer.

According to a research conducted by the Ottawa Hospital, a common treatment for erectile dysfunction combined with the flu vaccine may be able to help the immune system mop up cancer cells left behind after surgery.

The study showed that this unconventional strategy can reduce the spread of cancer by more than 90 percent in a mouse model. It is now being evaluated in a world-first clinical trial.

"Surgery is very effective in removing solid tumours," said senior author Rebecca Auer.

"However, we're now realizing that, tragically, surgery can also suppress the immune system in a way that makes it easier for any remaining cancer cells to persist and spread to other organs. Our research suggests that combining erectile dysfunction drugs with the flu vaccine may be able to block this phenomenon and help prevent cancer from coming back after surgery."

The current study investigated sildenafil (Viagra), tadalafil (Cialis) and an inactivated influenza vaccine (Agriflu) in a mouse model that mimics the spread of cancer (metastasis) after surgery.

Auer is now leading the first clinical trial in the world of an erectile dysfunction drug (tadalafil) and the flu vaccine in people with cancer.

It will involve 24 patients at The Ottawa Hospital undergoing abdominal cancer surgery. This trial is designed to evaluate the safety and look for changes in the immune system. If successful, larger trials could look at possible benefits to patients.

"We're really excited about this research because it suggests that two safe and relatively inexpensive therapies may be able to solve a big problem in cancer," said Auer. "If confirmed in clinical trials, this could become the first therapy to address the immune problems caused by cancer surgery."

Using a variety of mouse and human models, Auer's team also made progress in understanding how erectile dysfunction drugs and the flu vaccine affect cancer after surgery.

Normally, immune cells called natural killer (NK) cells play a major role in killing metastatic cancer cells. But surgery causes another kind of immune cell, called a myeloid-derived suppressor cell (MDSC), to block the NK cells.

Auer's team has found that erectile dysfunction drugs block these MDSCs, which allows the NK cells to do their job, fighting cancer. The flu vaccine further stimulated the NK cells.

"Cancer immunotherapy is a huge area of research right now, but we're still learning how best to use it in the time around surgery," said first author Lee-Hwa Tai. "This research is an important step forward that opens up many possibilities."

The study is published in the journal OncoImmunology.

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Here's how social isolation may increase stress, agression and fear



Researchers have found that long term chronic isolation cause the build-up of a chemical in the brain, that increases stress, aggression and fear.

The mice isolated for two weeks showed behavioural changes like, increased aggressiveness towards unfamiliar mice, persistent fear, and hypersensitivity to threatening stimuli.

When encountering a threatening stimulus, mice that have been socially isolated remain frozen in place long after the threat has passed, whereas normal mice stop freezing soon after the threat is removed, the research said.

Although the study was done in mice, it has potential implications for understanding how chronic stress affects humans and has potential applications for treating mental health disorders, said lead author Moriel Zelikowsky, postdoctoral scholar at the California Institute of Technology in the US.

Previous studies have determined that social isolation for two weeks in mice resulted in the upregulation of the signalling molecule neuropeptide, tachykinin 2 (Tac2)/neurokinin B (NkB) -- a short protein molecule.

In the new study, published in the journal Cell, the team found that chronic isolation leads to an increase in Tac2 gene expression and the production of a neuropeptide called neurokinin B (NkB) throughout the brain.

But, administration of a drug that chemically blocks NkB-specific receptors enabled the stressed mice to behave normally, eliminating the negative effects of social isolation.

On the other hand, artificially increasing Tac2 levels and activating the corresponding neurons in normal, animals led them to behave like isolated and stressed, the research showed.

Suppressing the Tac2 gene in certain different brain parts, increased fear behaviours, or aggression accordingly, implying that it must increase in different brain regions to produce the various effects of social isolation, the researchers said.

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Fasting every other day? It could increase diabetes risk

Representational picture

Washington D.C.: Intermittent fasting diets could increase diabetes risk, suggests a study. These findings suggest that fasting-based diets may be associated with long-term health risks and careful consideration should be made before starting such weight loss programmes.

In order to investigate whether an intermittent fasting diet could also generate damaging free radicals, Ana Bonassa and colleagues, from the University of Sao Paulo in Brazil, examined the effects of fasting every other day on the body weight, free radical levels and insulin function of normal, adult rats, over a 3-month period.

Although the rats' body weight and food intake decreased as expected over the study period, the amount of fat tissue in their abdomen actually increased. Furthermore, the cells of the pancreas that release insulin showed damage, with the presence of increased levels of free radicals and markers of insulin resistance were also detected.

Ana Bonassa commented, "This is the first study to show that, despite weight loss, intermittent fasting diets may actually damage the pancreas and affect insulin function in normal healthy individuals, which could lead to diabetes and serious health issues."

Ana cautioned, "We should consider that overweight or obese people who opt for intermittent fasting diets may already have insulin resistance, so although this diet may lead to early, rapid weight loss, in the long-term there could be potentially serious damaging effects to their health, such as the development of type-2 diabetes."

The findings were presented at the European Society of Endocrinology annual meeting, ECE 2018.

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This protein can treat triple-negative breast cancer

Representational Image

Researchers have developed a remedy to thwart the metastatic spread of breast cancer, a leading cause of death among women. The findings, published in the journal Nature Communications, showed that by inhibiting a protein called TAK1, the researchers were able to reduce lung metastasis in mice with triple-negative breast cancer (TNBC).

TNBC is a deadliest type of breast cancer that comprises 20 per cent of breast cancer cases and is particularly difficult to treat.

"For this subtype of breast cancer, few treatment options are available to target metastasis, and typically, these treatments are associated with high toxicity," said co-author Min Yu, Assistant Professor from the University of Southern California.

"A better understanding of tumour cells and their interactions with organs and tissues could help us design targeted therapies specific for metastasis," Yu added.

According to the study, TAK1 enables malignant cells from the breast to survive in the lungs and form new metastatic tumours.

Metastasis are the most common cause of cancer-related death.

There is already a potential drug, called OXO -- that can inhibit TAK1 -- and presumably make it much more difficult for breast cancer cells to form lung metastases. However, OXO is not stable in the blood, and therefore would not work in patients, the researcher said.

The researchers developed a nanoparticle -- consisting of a tiny fatty sac -- that works like a smart bomb to carry drugs through the bloodstream and deliver them directly to tumours.

The scientists loaded this nanoparticle with OXO, and used it to treat mice that had been injected with human breast cancer cells. While OXO did not shrink primary tumours in the breast, it greatly reduced metastatic tumours in the lungs with minimal toxic side effects.

"For patients with triple-negative breast cancer, systemic chemotherapies are largely ineffective and highly toxic. So nanoparticles are a promising approach for delivering more targeted treatments, such as OXO, to stop the deadly process of metastasis," Yu noted.

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Treatment for cancer is incomplete without a 360-degree approach

Cancer care
Former ATS chief Himanshu Roy took his life earlier this month. While his suicide note didn't mention a reason, doctors and friends claim repeated recurrence of cancer had broken him, and he was low.

When the fight to overpower the disease is long-drawn, often with no light at the end of the tunnel, patients don't just need medication but also counselling and physical therapy.


Viji Venkatesh

"There is a stigma associated with cancer in our society. Such that people even lose their jobs after it being detected, which adds to the financial stress. With such physical and mental strain, it is important to have a third person to share your problems with and help you cope," says Viji Venkatesh, region head, South Asia, The Max Foundation, an organisation that works for cancer patients.

"We get 60,000 new cases every year. We are able to sustain and offer proper support because of our network of support groups, where patients are provided encouragement at every level. In order to beat the darkness accompanying the disease, patients need something to look forward to. Every year, we take a group of patients for a trip to Goa; we organise group talk sessions with other patients and celebrate all festivals. We have identified 90 places with cheap accommodation near the [Tata Memorial] hospital, and we also have yoga sessions. All these small initiatives help build the psychological strength of the patient," explains SH Jafri, head of CSR and PR, and international patient advisor at The Tata Memorial Hospital, Parel.

Experts explain why a holistic approach to cancer treatment is essential.

The body
Patients have less muscle mass due to weight and protein loss in the body. Hence, there is a need to improve the quality of life by giving the right exercises and dietary plan based on the different stages of treatment to improve strength. "Cancer treatment is teamwork — the counsellor, physiotherapist, nutritionist and oncologist need to work together. One must understand the capacity of the body, how much it can take; this can be gauged only by a professional," elaborates Dr Nilesh Makwana, director and consulting physiotherapist, Muscle N Mind Physiotherapy Centre.


Dr. Nilesh

Chances of a relapse in some kinds of cancers reduce when the patient undergoes physical therapy. An expert will understand the fatigue level of the patient and devise a plan based on the kind and the stage of the disease. For example, during treatment, in addition to the pain medication given by the doctor, a physiotherapist will use electrotherapy modalities such as TENS to relieve the pain and block the pain channels and improve joint mobility and the properties of the muscle. The treatment for relapse patients is different as the intensity of their medication is higher. "Different cancers need different treatments. For example, one of my patients had lung cancer, for which a part of the lung had to be removed. This reduces lung capacity. So, we improved the stamina by giving rehabilitation with oxygen, so that the other part of the lung gets enough oxygen to oxygenate the rest of the body. Another patient suffering from bone cancer had the thigh bone removed, and a knee and hip replacement at an advanced stage. Plus, the chemotherapy had reduced the body mass. We devised a strengthening programme for the lower body, without oxygen procedure one would need for lung cancer, modified footwear to repair the body imbalance and other procedures," shares Dr Makwana.

The mind
"The need for counselling begins right from when the cancer is detected. Acceptance of diagnosis is difficult. The patient and the family need to know the outcome of the disease — you cannot just tell the patient that everything will be alright," says Dr Adwaita A Gore, medical oncologist, Zen Multi Speciality Hospital. Acceptance has to come from the family as only then will they have the collective strength to support the patient. Dr Gore has seen cases where a delay in treatment was caused because the family refused to accept the truth.

The link
Dr Gore says that doctors identify the main caregivers as they are the vital link between doctor and patient. Patient interaction with the doctor will be for a short period, as compared to a close member who will motivate the patient throughout. The stress also takes a toll on the caregiver, hence s/he too needs a support group.

Occupy your mind
Try and continue working unless the treatment demands one to stop. This helps to continue the treatment.


Dr Adwaita A Gore

The talk
Counselling differs for all age groups. "For someone who is going to undergo an operation for throat cancer, he or she needs to know before the surgery that they might lose their voice. It's only a counsellor who can successfully explain that while you may lose your voice, there are now techniques available to enable you to speak again," says Dr Gore.

Financial counselling
"Financial counselling is crucial to motivating patients to continue treatment. They need to know that their family can be taken care of after they are no more," says Dr Gore.


Madhu Kastia, 57, housewife

Survivor speak
You have to believe that you can fight cancer — without that, you can't do anything. Think of it as regular fever. I was diagnosed with ovarian cancer in 2014, and breast cancer in 2017. I was always into painting, and it was suggested to me that I pursue it to aid my treatment. I would finish one painting at every chemo session. I have gifted my works to my doctors, and a few have been displayed at Breach Candy Hospital. At hospitals, I would counsel other patients to be strong and take part in everything to live life like any other healthy person. I was advised by my doctors to pursue aqua aerobics and it has helped me improve my heart functioning from 25 to 40 per cent. My doctors emphasised the importance of physiotherapy. After my breast cancer surgery, I could move my hand easily because of physiotherapy. I had no hair when my daughter got married. But my supporters helped me in my fight, and to move on. Even getting a good wig that looks close to your real hair really helps build your confidence. My biggest support system has been my daughters and my husband.

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Beat the heat with these healthy thirst quenchers



Summer brings along with the struggle to find the right thirst quencher, or rather the healthy thirst quenchers. You should not opt for aerated drinks for aerated drinks to quench your thirst, because drinking aerated drinks can add unnecessary body weight. Instead, try lassi, coconut water, and sugarcane juice, suggest experts. Culinary researcher Akanksha Dean lists some healthy thirst quenchers to opt for in this scorching summer:

1. Coconut water: This is the most natural drink after regular water that helps you keep yourself hydrated during summers. It is naturally refreshing and boasts of a sweet nutty taste. Coconut water is the clear liquid that is extracted from a young green coconut, usually a harvest between 5-7 months. It rehydrates the body as it comprises of processed carbohydrates in the form of electrolytes and sugar, which in turn help balance the water levels in the body.

2. Lemonade: Possibly the most popular beverage in the world, it helps energise your body as well as kill your thirst. It is an excellent source of Vitamin C and helps in improving digestion. The good part about this beverage is that it helps in cleansing your body and reduces the risk of experiencing heartburn or bloating.

3. Lassi: The beverage is traditionally served in earthen clay pots, referred to as 'matkas', which aid in providing the instant coolness that is associated with the drink. This smoothie-like drink is made from yoghurt and boasts of a creamy texture. It is sweet in flavour, but can also be enjoyed in a savoury form. It is an excellent digestive and helps in energising the body as well.

4. Sugarcane juice: This is the perfect drink to beat the heat during the summer months. Sugarcane juice also serves as an energy drink. A glass of cold sugarcane juice can help rebuild the depleting energy levels in your body. It is rich in antioxidants, acts as a diuretic and helps keep your liver strong.

Dietician Jasleen Kaur, also the Founder of Just Diet, said: "It is loaded with abundant carbohydrates, proteins and minerals that our body needs. It is rich in antioxidants so it is great for dehydration. It has a surprising number of health benefits."

She lists four major benefits of sugarcane juice:

1. Immunity booster: Sugarcane juice is one of the best sources of instant energy. It is full of essential antioxidants that help our immune system. It reduces infections in the stomach, liver and respiratory zone. It fights against a number of diseases like cancer. It can help you to boost energy levels.

2. Rich in antioxidants: Sugarcane juice helps in cleansing the harmful toxins and other bad components from our body. It helps in boosting the metabolism of the body. It contains natural sugar which helps us to manage our weight.

3. Helps in proper digestion: Sugarcane juice acts as a good digestive tonic. It is very useful in treating the problem of constipation. It also helps maintain the acid base balance in our body.

4. Removes mouth odour: If you have a problem of bad breath or mouth odour, you should consider sugarcane juice as a home remedy. It contains calcium that helps build our strength including bones and teeth.

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Mild tremors experienced in Palghar district

Thane: Tremors measuring 3.1 on the Richter scale were experienced at around 1:38 am on Sunday in Dundalwadi village in Dahanu area of neighbouring Palghar district, a civic official said.

District Disaster Control Officer Vivekananad Kadam said no damage was reported. Earlier, on November 24 and November 3, tremors of the magnitude of 3.3 on the Richter scale shook Dahanu and Talasari talukas.

Civic officials said that quake-preparedness training programmes were held for villagers between November 26-29 in two talukas of Palghar district.

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Mumbai: 'Malfunctioning' superbike causes Virar man's death

A nagging defect in his superbike allegedly led to the death of biker Zoheb Merchant, 28, on Sunday morning. The Virar resident was on his way home after a joyride with his biker gang, when the front brake of his MV Agusta F3 800 jammed at Manor, throwing him off in another direction. This was the third time his superbike had malfunctioned since he bought it.

Merchant is survived by his parents, three brothers, wife and a six-year-old son. He was the eldest in the family and had a business selling firecrackers. The incident occurred on Sunday morning when Merchant and his group of 15-18 bikers had gone on their usual Sunday ride from Virar to Dahanu. When they were on their way back, the front brake of Merchant's bike allegedly jammed, leading him to lose control of the bike and ram into a divider.


Front brake of Merchant's bike allegedly jammed, leading him to lose control of bike and ram into divider.

One of his friends said, "We have a bikers' group and every Sunday morning, we ride the bike while following proper safety and traffic norms. Whatever happened came as a huge shock to us. Suddenly, some defect occurred in his bike, jamming the brake of the front tyre disc, which then led to him losing control of the bike and falling on the road." Third time Since they were riding at full speed, the impact of the malfunction became such that he was thrown off the bike in another direction. His vehicle, meanwhile, fell near the direction of the Ahmedabad-Mumbai National Highway.

Merchant's bike is manufactured by the Italian motorcycle maker MV Agusta, and retails for around R 20 lakh. According to his friends, since he bought it, he'd faced the same defect twice, which is an electric malfunction that jams the front tyre disc. He'd got it fixed and extended the vehicle's warranty till March 2019. He'd also written a Facebook post about the earlier issues he faced. However, the same defect occurred a third time, leading to his death.

Cause of death not known Another friend said, " We managed to bring an ambulance to the spot and took him to a government hospital on the highway, where he was declared dead on arrival. Looking at his body, doctors were shocked at not finding any external injuries." He had minor injuries on his head due to the impact of the fall. The cause of death has not been revealed as the post-mortem report is yet to be released. His friends suspect he died of internal bleeding.


This is the third time the MV Agusta 800 had allegedly malfunctioned.

While the case had initially been registered at the Virar police station, the matter has been transferred to the Manor police station as the incident occurred in their jurisdiction.

An officer from Virar police station said, "We have registered a case under section 304( a) ( death by negligence) of the Indian Penal Code and various sections of the Motor Vehicles Act against unidentified accused." Motoroyale, the dealer from whom Merchant bought the bike, couldn't be reached for comment.

18 No. of bikers in Zoheb's group

3 No. of times his bike glitched

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Experience flight of poetry with this Bengaluru psychaedelic rock band

Parvaaz, a four-member outfit, believes in spreading the message of peace through their progressive rock music with guitar-driven compositions. With their Urdu lyrics and the familiar sound of chimes, the soundscape is a refreshing change. Now, they are back in the city for a gig that promises to be about the coming together of western guitar techniques and Indian elements, making them one among a handful of true-blue fusion indie bands today.

Parvaaz, which translates to "flight", came together in 2010 when childhood friends Khalid Ahmed and Mir Kashif Iqbal (both on vocals and guitar), reconnected in Bengaluru over their shared love for blues rock melodies, and were joined by Sachin Banandur (drums and percussions) and Fidel D'Souza (bass). But they only started developing their own sound two years later. "We were playing at competitions and winning, which was a great boost. We felt confident enough to make original music, and our sound shifted towards progressive and classic rock of the '60s and '70s," says Ahmed, quoting Pink Floyd, Led Zeppelin, The Doors, and Indian Ocean and Avial, as their influences.

It was a process of trial and error till they found the best way to let all their individual influences flow while jamming, which is when the Urdu lyrics also came in, the natural form of communication for two members at least. "Hindi and Urdu come naturally to us. Singing in English would have just not flowed with the music. Besides, the sound of the fusion that comes out of a merging of different styles of music is what our goal has been. It is the sound that guides most of our writing," says Ahmed.

Their lyrics primarily talk about the human nature and comprise metaphorical poetry, like their song Beparwah, which talks about man's dependence on materialistic objects, and Shaad, which is about loss and regret.


Khalid Ahmed

But lyrics are the last thing that get added onto their music, and that too if they deem it necessary. "A lot of our jams just end up being instrumental, and hence our seven minute-long songs," reasons Ahmed.

They will also be playing some new songs from their upcoming album that they have been putting together for four years, and will be releasing later this year. For fans who like to sing along, they will also perform songs from their first EP and debut album, including Ziyankar and the achingly serene Itne Arse Ke Baad, which echoes a longing to go back home. Home, for Ahmed and Iqbal, is a sensitive issue now, since both hail from Kashmir, which is still trying to heal from the Pulwama attack. Both were reluctant to comment, and as they say, prefer to let their music do the talking.

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Traffic constable in coma for eleven months dies in Worli residence

Rajendra Jadhav, a traffic constable who remained in a comatose state for the last eleven months died on Sunday night at his residence in Worli. Jadhav, who was posted at Tardeo Traffic Division, had collapsed while on duty in April 2018 after suffering a stroke.

After treatment in Bhatia Hospital, he was shifted back to his home as per doctor's instructions as there was no improvement in his health. He passed away in his residence, his last rites were performed at the Worli Crematorium on Monday afternoon.

A batchmate on condition of anonymity said, "Jadhav's family was receiving his salary up until now. But the worry is what happens to his 7-year-old son, who suffers from rare congenital heart disease and needs an injection every alternate day for the same? We are currently trying to collect funds in order to aid his family," he added.

The fateful day
On 2nd April 2018, Rajendra Jadhav was walking towards a traffic chowky at Nana Chowk, Tardeo, when he suffered a stroke and collapsed on the ground. He was rushed to Bhatia Hospital, where it was revealed that he suffered a cardiac arrest due to which his brain was deprived of oxygen supply. After a month’s treatment, he slipped into a coma.

After being treated at Bhatia Hospital, which is not on the panel of the Mumbai Police Health scheme, he was shifted to Bombay Hospital followed by JJ Hospital. "Due to cardiac arrest, Jadhav went into a vegetative state," informed a colleague of Jadhav on condition of anonymity.

Babasaheb Dhangar, the constable in-charge at Tardeo Traffic said, "I worked with Jadhav for almost 4 years. He was very loyal and always ready to lend a helping hand. From the day he fell ill, we tried our best to help him and his family. We collected around Rs 4 lakh through contribution and his batch mates, too, contributed as much as they could," he added.

After initial treatment at Bhatia Hospital, Jadhav was shifted to Bombay Hospital. After a brief stay for a month, Jadhav was taken home as per instructions by the doctors. Another surgery was performed on him at JJ Hospital but it was not successful. 

Also Read: Mumbai: 25-year-old constable risks life to save family from blaze in Girgaum

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Fifty shades of music at this eight-hour concert in Lower Parel

It was in March 2018 that we had first written in these pages about Awestrung, a monthly gig series held at a Lower Parel mall. But after that, all information about subsequent editions had dried up. The reason is that the organisers had temporarily shelved the property because they felt that they needed to refresh the format, and come back with something bigger and better. And that's exactly what's happening this weekend when Awestrung returns on an unprecedented scale, with 50 artistes from diverse genres sharing the stage.

This comeback was orchestrated after Artists Aloud — the indie wing of a major music company — approached the folks at High Street Phoenix, the mall where the concert is held, with a proposition. Soumini Sridhara Paul, VP of Artists Aloud, tells us, "When we started speaking [to the mall authorities], we told them that we have a format where, in 2012, we had brought in 50 artistes to perform together on stage. We said, 'Why not replicate that model for Awestrung?' They replied, 'Let's do this.' And that's how we came to be partners."


Soumini Sridhara Paul

She adds that the line-up is curated in such a way that the emphasis is on independent artistes making original music. So, you have a Hindi rock band like the Delhi-based Faridkot. There's local electro-rock act Laxmi Bomb. Manganiyar mainstay Mame Khan is on the bill, too, as is rapper ACE of the crew Mumbai's Finest. Then there are electronic producers, singer-songwriters and Sufi acts, among others who complete the list of performers. In short, name it and chances are that you will have an act playing a genre you like.

Each outfit will get a maximum of 10 minutes on stage so that things keep moving, with a compère, Mihir Joshi, keeping the audience entertained in the interim. Mame Khan is the penultimate performer, before Smokey, a Mumbai-based DJ, brings the show to an end. She tells us, "Imagine, I am closing the festival. So, all the focus will be on me and there's thus a bit of both, nervousness and excitement. But I'll keep my set chilled, so that it's a nice goodbye for everyone." Which is just as well, because after the gamut of music that will be on offer, a mellow note is possibly the best way to end this massive, eight-hour concert.

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Khar eatery to host a pre-launch party for Avengers fans

The Endgame is near, and we are talking quite literally here about the latest instalment in the Avengers series of superhero movies, which releases on April 26. After this week's brouhaha over Game of Thrones Season 8, it's the next big visual experience that has sent fans in a tizzy. And a pub in Khar is now hosting a pre-launch party of sorts for them, with various activities and F&B offers themed around the film.

"We have collaborated with digital community Things2doinMumbai, and brought ticket sponsors on board for the event. In terms of the activities, there are Avenger- related games and trivia, winners for which will get free tickets and discounted ones when the movie releases. We also have an array of themed cocktails in store," says Pragnesh Rai, owner of SamBar, which will host the evening, adding that there are a number of discounts on the existing menu, too, with drinks starting at Rs 39.

The cocktails include a beer-based one called black wid'wow; iron anna, which has whisky; tha end, which is vodka-based; and a super-potent Long Island iced tea that's aptly named hammered by Thor.

As for the games, these include Ant Man, where a player will be given three soda bottles and raisins. The aim is to drop these raisins from eye level into all three bottles, without bending down. Then there's Black Widow. For this, one person will hold a hula-hoop and another will have a fake spider placed on his head. The latter has to go through the hoop in the shortest possible time, without dropping the spider. All in all, it sounds like an event perfectly suited for fans of the Avengers. And even if you aren't one, you can still gain from the cheap booze, meaning it's a win-win.

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Mumbai: UN Women India launches video campaign 'Mujhe Haq Hai'

UN Women India launched a video campaign called #MujheHaqHai on Wednesday which emphasises the power and potential of women in today's world.

The video features a host of independent and courageous women, who have excelled in their respective spheres and mapped India globally. The video sends out a strong message for female empowerment to women all over India with the belief that they have an equal participation in all walks of life.

Apurva Purohit, the President of Jagran Group, is one of the prominent personalities featured in the video alongside the likes of Aishwarya Rai Bachchan, Mithali Raj and Sania Mirza, to name a few.


Apurva Purohit, President, Jagran Group

Apurva Purohit said, "It’s an absolute honour to be a part of this initiative by UN Women India. Any and every small step towards the empowerment of women and giving them their rightful place under the sun is the need of the hour today. We need more examples of women who are breaking barriers every day so that the girls tomorrow can rise and shine. While there is enough discourse on everything that is not right, this initiative is a beacon of hope, one that celebrates the struggles, dreams and aspirations of women who have emerged as winners. #MujheHaqHai is an ode to the undying spirit and grit of the woman of today."

At the launch event, mid-day online caught up with Nishtha Satyam (Deputy Representative UN Women India MCO), who stated that, "Through this event, we are trying to create a movement that is based on Human Rights, a movement that recognises women rights as Human Rights, where women exercise their voice and make choices without any fear or judgement, and shape their careers and lives. We are trying to create a movement based on women understanding their own rights as individuals."

Talking about the outcome, she added, "Women should realise their own potential and rights and be able to pursue their dreams without any inhibitions or fear of repercussions. That would be the grandest outcome from a movement like this."





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Ghatkopar plane crash: Pilot's presence of mind saves hundreds

The Ghatkopar plane crash, which killed five, yesterday would have ended up becoming a mammoth disaster, considering it crashed in a densely populated residential area, had it not been for the pilot's presence of mind. Several residents from the area and eyewitnesses said the pilot did a good thing by ensuring the aircraft crashed at an under-construction site, avoiding the residential buildings in the vicinity.

Emergency response
The accident took place when the plane was about to land at Mumbai airport. The four onboard — pilot, co-pilot and maintenance engineers — and a passer-by on whom the wreckage fell have been identified as the deceased. Immediately after the incident, the fire brigade and police reached the spot, and within minutes pictures and videos of the crashed plane and a charred body near the crash site went viral on social media.

Afternoon happenings
mid-day spoke to residents from the area to find out what exactly happened, and most said it all started in the afternoon when they heard a deafening explosion, followed by thick smoke and a tree on fire. Locals said the situation would have been worse had the aircraft crashed on a residential building or the busy LBS Marg, which is adjacent, or the Versova-Andheri Ghatokpar Metro corridor, which, too, is just a few hundred metres away.

A paan shop owner from the area said, "I was sitting in my shop when I heard a loud noise. At first I thought a tyre of some truck busted, but then, a person from the MTNL lane came running to my shop and said a plane had crashed. "We should all be thankful to the pilot, as by crashing it at an under-construction site, he saved hundreds of lives."

Also Read: Mumbai: Chartered plane crashes in Ghatkopar; five killed





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Mumbra girl missing since 2016, finally tracked through Tik Tok app

Thane: A girl who had gone missing in 2016 from Mumbra was found in Goregaon through a post on social media site Tik Tok. Police took her into custody and learned that the girl went on her own accord.

According to Mirror Now, a woman on November 6, 2016, registered a complaint at the Mumbra police station that her daughter had been abducted. Acting on the complaint, police began searching for her through various means but were unsuccessful. The case was later transferred to the immoral trafficking prevention cell on May 11, 2018. Assistant Sub-Inspector Raju Mahale was appointed to investigate the case.

During the investigation, Police learned that the kidnapped girl has been using Tik Tok and shared it on social media. Police began tracking the girl on social media and asked her to make a video call. After confirming the identity, the police asked the girl to meet her sister under a false pretext of her mother being ill. She was then taken into custody and cops began interrogating her.

During the interrogation, the girl revealed that she left home on her own accord and not under pressure or threat from anyone. As a result, the kidnapping charge was dissolved. She also revealed that after running away from Mumbra, she was living in Goregaon for ten days and later started a catering business in Surat for 3-4 months. Later, she shifted to Vasai for few months. Since then, she has been living in Nalasopara.

On further investigation, it was revealed that the girl had made a fake account under the name of Abhay Shetty and befriended her sister and her husband after watching a video of them on Tik Tok ten days ago. The sister and her husband had uploaded a video of Bhojpuri song on a Tik-Tok mobile app. The girl began to chat with her sister and her husband and ask information about the family.

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Cops silence noisy bikers in Thane

Thane rural district's Navghar police are finally making the right noises following repeated complaints against noisy bikers by locals. The police have begun a heavy crackdown against bikers using modified silencers that create much noise, contributing to the already terrible noise pollution levels in the city.

The police are not just seizing such bikes but also destroying the modified silencers in front of their owners. More than 55 cases have been registered so far in this regard and more than 35 silencers have been destroyed in the last couple of weeks.

People living in Bhayander East have been forced to endure a cacophony of noises that the modified silencers or bikes with no silencers at all make. Also, patients admitted to nearby hospitals had complained to the local police on multiple occasions but no concrete action was taken so far.

Police fool violators
Action initiated against such bikers in the past has posed quite some challenge to the police who claim that if these bikers are followed, most of them speed away without a thought for their own lives or that of others. In such a situation, it is difficult to catch hold of them, said an officer of the Navghar police station. "We thus adopted a new method. We have formed a special team, members of which dress up as different people - beggars and godmen - and patrol areas around traffic signals to nab such bikers. The idea has worked so far," said PSI Vijay Takke from Navghar police station.

Locals have welcomed the move. "It is a nightmare for us as these bikes zip past our houses almost every day and it becomes extremely disturbing, more so for children and elderly people," said a local who had filed many complaints against errant bikers in the past. "The police action has now reduced the number of noisy bikers but the drive must not stop," he added.

55
No. of cases against errant bikers registered so far

35
No. of modified bike silencers destroyed so far

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Maha deputy engineer gets 16 months jail sentence for accepting bribe

A Maharashtra government official was Thursday sentenced to 16 months rigorous imprisonment by a court in the neighbouring Raigad district for accepting a bribe.

Raigad Additional District Judge BC Kamble convicted Ashik Bharti, a deputy engineer with the Kharbhoomi Sarvekshan and Anveshan Department of Pen, under the Prevention of Corruption Act and fined him Rs 5,000, said a senior Anti-Corruption Bureau official.

Deputy Commissioner of Police (ACB) Mahesh Patil said Bharti had demanded Rs 5 lakh from a contractor to get his bills cleared. The contractor approached the ACB following which a trap was laid on November 6, 2015, and Bharti was nabbed while accepting Rs 1 lakh, Patil said.

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Fake currency notes worth Rs 15.76 lakh seized in Thane

Counterfeit notes with a face value of Rs 15.76 lakh were seized from three persons in Mumbra area here in the early hours of Saturday, police said.

Assistance Commissioner of Police Ramesh Dhumal said the police had received a tip-off that some persons were going to arrive in Kismat Colony, carrying counterfeit notes with them.

Jainkumar Chunnulal (41), Mohammad Dilshad (26), both from Uttar Pradesh, and local resident Javed Ahmed Ansari (30) were arrested and a bag of counterfeit notes in Rs 2,000 denomination was seized from their possession, he said.

Jainkumar and Dilshad had allegedly procured the notes from Asansol in West Bengal by paying Rs 3.50 lakh, the ACP said. Police were probing if the contraband had any link with the ongoing election campaign, he said.

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Concert to cheer up children undergoing chemotherapy at Parel hospital

So many of us have lost someone we know to cancer. So when 15-year-old Devika Madgavkar, who was volunteering at the Tata Memorial Centre and working with kids with cancer, asked Alfred D'Souza, the director of her choir Stop-Gaps Junior Choral Ensemble, if they could do something to cheer up the children undergoing chemotherapy, he thought, "why not?"

And Carnival in Song was born. "Madgavakar wanted to do something for the kids, who she observed were quite self-conscious and distant after they lost their hair. Also, many of them hail from a low social economic background. The event is just before Lent, which begins on March 6, and as it's the season of hope, we wanted to brighten up their li­ves. I prepared two choirs and reached out to others, who agreed immediately," says D'Souza.


The Salvation Singers

The audience will get to hear ha­ppy numbers, and renditions of peppy tracks with a samba or calypso beat, akin to what you hear at a carnival, shares D'Souza, adding that while the Stop-Gaps Choral Ensemble will be performing Brazil and Senorita, The Salvation Singers will offer a medley of Hindi songs, and Siddharth Meghani will perform some Elvis Presley tracks. The line-up will also include The Victory Chorus Line, and soloists such as Ella Atai, Kim Cardoz, Mehmood Curmally and Darren Das, accompanied by Mimosa Almeida Pinto (piano) and Ishan Jadwani (drums), besides dancers on stage.

"We've been planning this since October. We have a lot of kids aged between five and 15 years, who have their term exams at the moment, but yet th­ey have been practising," adds D'Souza. All proceeds from the evening will be given to the centre's Runners of Hope Initiative.

ON March 1, 7.45 pm onwards
AT St 
Andrew's Auditorium, St Andrew's College, St Dominic Road, Bandra West 
LOG ON TO bookmyshow.com

CALL 26410926
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Aamir Khan celebrates birthday with media; makes special announcement

Aamir Khan had a customary cake-cutting ceremony with the media at his Bandra home, holding a press conference. On his birthday, the actor, who turned 54 today, made an announcement of his next film titled Laal Singh Chadda. Aamir's next release is a remake of Hollywood film Forest Gump (1994). The film starred Tom Hanks and Robin Wright and was based on a novel of the same name.

Following this, Aamir Khan will take off for North Ireland to attend the ongoing Belfast Film Festival. He will be in conversation with Nasreen Munni Kabir on 16th to discuss his body of work.

Check out the pictures of Aamir Khan's 54th birthday celebrations here. (All pictures/Shadab Khan, Yogen Shah)


Aamir Khan's 54th birthday celebration

Aamir Khan was accompanied by his wife Kiran Rao.


Aamir Khan cuts his birthday cake

Fans across the nation have been pouring in wishes for Aamir by posting the actor's pictures, which also saw a strong social trend with the #HappyBirthdayAamirKhan.


Aamir Khan and wife Kiran Rao at his 54th birthday celebrations with media persons


Kiran Rao clicked while feeding the birthday cake to Aamir Khan

Known as Mr Perfectionist of the industry, Aamir Khan for Bollywood has over the years created an image that many look up to. From making films that address the pertinent issues of the society, to speaking his mind on raging issues even off camera, Aamir Khan has always been the one with a calculative brain and has used his position to impart a change in the society.

On the professional front, Aamir Khan likes to explore with the character he plays and the actor likes to surprise his fans with new characters. To experiment with roles, Aamir grows his hair and beard before every film. This also gives him the flexibility to play with multiple looks in one film. We wonder, what Aamir Khan's look would be in Laal Singh Chadda!

Here's wishing a very happy birthday to Aamir Khan!

Also Read: Aamir Khan is a family man, these picture-perfect frames are proof!

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Taimur Ali Khan plays Holi with the paparazzi at his Bandra residence

It is the festival of colours and most of the people are celebrating their day of happiness with family and friends. Saif Ali Khan and Kareena Kapoor's son, Taimur Ali Khan, who is already a social media sensation, was spotted celebrating Holi with the paparazzi, whom time and again, he is seen waving and smiling at! 

A video shared by one of Taimur's fan club, where the tiny tot is seen playing with the water gun at his Bandra residence, has become a wave on the net. Take a look!

Taimur, in his house, is seen in a playful mode while spreading joy with his smile and spraying water from the balcony.

Meanwhile, Soha Ali Khan, sister of Saif Ali Khan, also shared a colourful pretty picture of Inaaya Naumi Kemmu on Instagram. Soha captioned the image: "Happy holi!!! [sic]"

 
 
 
View this post on Instagram

Happy holi!!! ❣

A post shared by Soha (@sakpataudi) onMar 20, 2019 at 11:25pm PDT

Isn't she looking adorably cute? 

Kareena Kapoor Khan, who is married to actor Saif Ali Khan, has time and again expressed concern over the growing paparazzi culture in India. She wondered how people could be so interested in her two-year-old son Taimur's life.

Also Read: Taimur Ali Khan is also a bookworm just like papa Saif Ali Khan; see photos

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Coolpad 'Note 6' with dual selfie cameras launched in India


Coolpad 'Note 6'. Pic courtesy/Twitter

Chinese handset maker Coolpad launched 'Note 6', an offline exclusive product in India on Tuesday. Two of the most notable features of Note 6 are 5.5-inch HD display and 8MP+5MP dual front cameras. The company in a statement said that smartphone will be available from Tuesday in 32GB and 64GB internal storage variants with 4GB RAM for Rs 8,999 and Rs 9,999 respectively.

Note 6 is powered by a Qualcomm Snapdragon 435 chipset, backed by 4,070 mAh battery and runs on Android 7.1 Nougat Operating System (OS). "Coolpad 'Note 6' will offer a great value for money smartphone for Indian customers," said Syed Tajuddin, CEO, Coolpad India.

"We are also planning to introduce more aggressive offline devices in the next few months to expand in the offline market through our retails partners and multi-brand outlets," Tajuddin added.

Coolpad "Note 6" will be available at over 300 multi-brand stores across eight states including Delhi-NCR, Telangana and Maharashtra.

(Edited by mid-day online desk, with inputs from IANS)

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Xiaomi 'Mi Music', 'Mi Video' launched in India

Xiaomi India on Wednesday announced the launch of "Mi Music" and "Mi Video" to offer value-added Internet services in India.

"With the launch of these two apps 'Mi Music' and 'Mi Video', we hope to serve millions of Xiaomi smartphone users with a better user experience through enhanced Internet services," Manu Jain, Vice President, Xiaomi and Managing Director, Xiaomi India, said in a statement.

"Mi Music" is a pre-installed music app which offers an integrated music streaming service along with the ability to store offline music and has nearly seven million daily active users in India, the statement said.

"Mi Video" is a pre-installed video app that provides integrated video streaming across platforms.

"Mi Video" content is currently powered by Hungama Play, SonyLiv and Voot. It offers more than 500,000 hours of content with nearly 80 per cent free content, the statement added.

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iVOOMi launches 'FitMe' health band at Rs 1,999


iVOOMi on Thursday launched its first health band, 'FitMe', in India at Rs 1,999. The fitness band sports a 90mAh battery, scratch-proof display heart rate monitor, sleep monitor, running mode, vibration reminder, pedometer, GPS and other features, the Chinese electronics company said in a statement

"The 'FitMe' health band is sleek, smart, dust-proof and water resistant and features a display of 128x32 pixels resolution that makes it crystal clear from all viewing angles," said iVOOMi India CEO Ashwin Bhandari.

With "IP67," the watch remains water-resistant for 30 minutes, has auto-sync for "Smart Me OS 2.0" and is capable of OTA (Over the Air Software) updates.

"FitMe" is chargeable without a USB cable; the display can be directly connected to any USB port to charge the device. The health band on available on Flipkart and 

Available on Flipkart, the health band comes with a six-month warranty.

(Edited by mid-day online desk, with inputs from IANS)

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Twitter working on encrypted messaging feature: Report


As data security concerns on Facebook and WhatsApp loom large, Twitter is reportedly working on a 'Secret' encrypted messages feature which could make the microblogging platform safer for sensitive communications.

With this feature, Twitter is expected to roll out options about encrypted messaging like starting a secret conversation and viewing both sides of the conversation for encryption keys to verify a secure connection, TechCrunch reported on Monday.

The encrypted Direct Message (DM) option was first spotted inside Twitter for APK that contains codes for unreleased features that companies are testing.

Instant messaging app WhatsApp uses "end-to-end encryption" in all conversations. This can be opted into Messenger.

End-to-end encrypted messages are secured with a lock and only the sender and recipient have the special key needed to unlock and read them.

For added protection, every message sent has its own unique lock and key. No one can intercept the communications.

Last week, WhatsApp co-founder and CEO Jan Koum quit reportedly "after clashing with its parent, Facebook, over the popular messaging service's strategy and Facebook's attempts to use its personal data and weaken its encryption".

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Twitter testing end-to-end encrypted messaging, say report

Representational picture

Washington: Twitter is reportedly testing a new feature on its Android app that makes messaging secure with end-to-end encryption.

Called 'Secret Conversation', the feature is expected to be available in the conversation info section in direct messaging of the Twitter app on Android, Mashable reports.

As users seek more security, end-to-end encryption has become a new mandate for messaging apps. The technology makes it difficult for snoopers to access or intercept messages which are exchanged between two parties.

NSA whistleblower Edward Snowden had asked Twitter CEO Jack Dorsey for such a feature on the platform a year ago. It remains to be seen when the end-to-end encryption is officially rolled out.

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5G India 2018 International Conference and Exhibition to be held in Mumbai

 

Digital Transformation with 5G – 2nd 5G India 2018 International Conference & Exhibition. The conference will be held on May 17 and 18, 2018 at The Leela, Mumbai

Bharat Exhibitions is organising the 2nd edition of the 5G India 2018 International Conference and Exhibition, bringing together India’s telecom industry leaders, policymakers and telecom analysts to discuss how 5G will enable the future ushering in a new India. The conference to be held on May 17 and 18 at The Leela, Mumbai will focus on issues and opportunities related to the deployment of 5G and high-speed digital applications that will drive cross-industry applications and spur digital transformation and connectivity to catalyze growth.

With 5G promising to bring about a sea change in the digital ecosystem by servicing more industries through one architecture, the conference will address the tremendous growth that promises to take place in the next few years to revolutionize the Indian Data market and help India to emerge as a qualitative internet market as against a quantitative one. Leading experts will speak about the challenges and opportunities that operators and technology providers will face in the transformation of mobile broadband to 5G.

The event will witness the 5G Demo by various organization (BSNL, Reliance Jio, Intel, IIT Hyderabad, IIT Bombay). The conference will include sessions and panel discussions on what will it take for India to emerge as one amongst the leaders in standardization for 5G technologies and applications, enabling the positive use of Artificial Intelligence for all, global perspectives on 5G, preparing for 5G, trends and drivers shaping 5G, spectrum and technology for 5G and a CXO Round Table on Digital Transformation with 5G.

Shri Manoj Sinha, Hon’ble Minister of Communications (Independent Charge) and Minister of State for Railways, Govt. of India will be the Chief Guest, Smt. Aruna Sundararajan, IAS, Chairman, TC & Secretary (Telecom), Department of Telecommunications, Govt. of India and Mr. Malcolm Johnson, Deputy Secretary-General, ITU will be the Guests of Honour, Introductory Address by Mr. Adrian Scrase, CTO, ETSI and Keynote will be deliver by Shri Anupam Shrivastava, Chairman & Managing Director, Bharat Sanchar Nigam Limited. 5G India 2018 International Conference and Exhibition is being supported by the Department of Telecommunications, Ministry of Communications, Govt. of India and the Ministry of Electronics and Information Technology, Govt. of India. With Broadband India Forum as the Knowledge Partner, the conference is also being supported by the industry associations including 3GPP, TSDSI, CEWiT India, COAI and TAIPA.

With plenary sessions, technical tracks in an innovative show formats and international case studies, the agenda will include visionary presentations from 30+ speakers across the globe including Mr. Klaus Pendl, First Counsellor – ICT, Delegation of the European Union to India, Mr. Sebastien Soriano, Chairman, ARCEP France, Mr. Daniel Brower, Vice President, Program, Deutsche Telekom, Mr. Julius Knapp, CTO, FCC USA and Dr. Wu Yong, Senior Standards Expert, 3GPP as well as Senior Spokesperson from BSNL, INTEL, Google, Savitri Telecom Services, Syniverse, Keysight Technologies, UTStarcom, Cambium Networks, CSG International, Rohde & Schwarz, Commscope, Infineon and Siae Microelettronica.

About Bharat Exhibitions

In a world where technology is erasing borders, it is indeed ironical that professionals find it increasingly difficult to maintain peer to peer contact on regular basis. Bharat Exhibitions fills in this space by managing and hosting some of India’s premier Telecom & IT events. We own niche and prestigious conference properties in the new generation technology arena such as 100 Smart Cities India, Cloud & Network Virtualisation India, 5G India, Data Centre India, Broadband Tech India, Smart-Sustainable Cities Technology & Innovation Summit, Cyber Security India, SMC Technology India and Telecom CXO Summit. We have a simple mission: Establish & deliver contacts that create value for your business.

For further details, please visit http://www.bharatexhibitions.com

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Ericsson launches customised network solutions for Indian market

Telecommunications service provider Ericsson on Thursday introduced a new category of radio products called Street Macro in India to enable a smooth evolution from 4G to 5G.

Street Macro is a new site type that addresses the need for operators to grow in cities with limited available radio locations.

The company also launched new radio products that support "Massive MIMO" technology to simplify use for wider 5G adoption.

"Operators today are looking at ways and means to increase network capacity, especially in urban areas. Ericsson's Street Macro adds a new layer in the network layer to boost capacity enabling service providers to cater to the growing demands of data users," Nitin Bansal, Managing Director, Ericsson India, told reporters here.

According to Ericsson's new economic study of enhanced mobile broadband, evolution to 5G will enable 10 times lower cost per gigabyte than current 4G networks.

To help operators capture growth opportunities presented by new 5G use cases, Ericsson has expanded its 5G Core System offering with new capabilities to support 5G New Radio (NR) standard and also enhanced its Distributed Cloud solution.

The announcement came on the sidelines of Ericsson's annual technology roadshow in India, where the company recreated a "Do Zone" to showcase the highlights from Mobile World Congress 2018.

To date Ericsson has signed 39 memorandums of understanding with service providers for trials, the company said.





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Samsung to launch Galaxy 'A' and 'J' series smartphones in India soon



Aiming to disrupt India's mid-segment smartphone market, Samsung is set to launch four new smartphones -- two each in Galaxy "A" and Galaxy "J" series -- this month.

The upcoming Galaxy A6 and Galaxy A6+ smartphones could be priced between Rs 20,000 and Rs 25,000 while the devices in Galaxy "J" series could cost customers Rs 15,000 to Rs 20,000, industry sources told IANS on Friday.

Two of the four smartphones in the upcoming line-up would come with dual camera set-up, the sources added.

All of them will be made at the company's Noida facility. The smartphones will feature Samsung's super AMOLED "Infinity Display" -- bezel-less screen that creates an immersive viewing experience.

Notably, Samsung's flagship smartphones such as Galaxy Note 8 and Galaxy S9 series feature the "Infinity Display". Now, with the upcoming devices, the display feature would be introduced at lower price points in the Indian market.

The South Korean giant first introduced the "Infinity Display" in Galaxy S8 series in 2017.

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Microsoft says, Artificial Intelligence facing large skills shortage


Microsoft

The fast-emerging field of Artificial Intelligence, which has suddenly caught the attention of the IT industry and the governments across the world, is facing a large skills shortage, a top Microsoft official has said.

The Artificial Intelligence (AI) is also facing the challenge of appropriate use of data, group programme manager of Microsoft Learning Matt Winkler told PTI.

"There is a pretty large skills shortage. Lots of folks are talking about it (AI). A lot of folks are very, very excited about it and then they want to go and make that real. And when they go to make that real, there's a really large skills shortage," Winkler said.

That's why it's so exciting to be trying to bring these technologies to more developers because it's going to bring more people into the mix, he said. Winkler said the second challenge is really around data.

"How do you get the data in the right shape? How do you prepare the data? Because all of the AI in the world is based on data, and so what makes it interesting is the data that you have, the data that your business has, that what you understand about your customers. So how do you most effectively use that data to go and produce models," he said.

Then within kind of any individual product project, one of the key challenges is the same thing that the industry has seen with software, which is, if one tries and do too much, the project gets much harder.

"And so we'll often times see failed projects, which are the result of trying to create just the most amazing thing having done nothing," he said.

At the recently concluded developers conference ¿ Build 2018 ¿ Microsoft's CEO Satya Nadella talked about how to make AI accessible for everyone.

"Our guidance to a lot of customers to pick a domain and pick a used case where you have a high, high-quality data and that it is really well understood. Start there, get some wins with that and then start expanding the use cases so far," Winkler said.

Microsoft is partnering with multiple players in both the private and governmental sectors to use AI for public good.

"Absolutely, AI is being used for public good. For instance, it is being used in school districts in order to predict drop-out rates in India.

"We see a ton of healthcare applications: patient re-admission rates is very very popular one. We have seen medical image analysis. We are doing some really interesting work doing diabetes prediction through scans of retinas," Winkler said.
Microsoft is working with the Snow Leopard Trust, a non-profit organisation dedicated to the preservation of the snow leopard and parts of Nepal and India to analyse in real time the presence of snow leopards.

"So it's fundamentally changed the way they do their research," he said, adding that the Microsoft is working with three-four other conservation agencies doing similar things.

"For a lot of the customers, what AI is enabling is not just an incremental... but It's something they fundamentally couldn't do before. So it really does introduce a step change for the things that they want to do in their business," Winkler added.

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Take the rumour mill with a pinch of salt

The recent frenzy over supposed cracks in the Kemps Corner bridge - the country's first-ever flyover - has been proved to be an overreaction, but also brings to light the power that WhatsApp has to spread misinformation and paranoia.

This paper yesterday reported that thousands of app users had received a picture of a fissure in a portion of the bridge, with claims that the flyover was in danger of collapsing. The viral photo sparked widespread panic; so much so, that the civic commissioner was drawn into the Kemps Corner frenzy. There was a post from a young politician seeking to reassure the public. The 86-year-old architect of the bridge also gave a statement to assuage fears and calm outrage bubbling on WhatsApp.

Through the days, more rumours came in, stating that the bridge was falling and traffic had been diverted. One can imagine the mental state of a motorist about to drive onto the bridge, if they were to glance at WhatsApp and spot the alarmist message. The rapid-fire messages sparked fear and anger. Reassurance, on the other hand, was much slower to come.

This shows just how important it is that we filter messages on WhatsApp, and not forward blindly. In this 'quick click' age, it takes just the push of a button to spread fear. Thankfully, the bridge fall phobia had no major repercussions, but it does bring to mind other times when WhatsApp messages have started and stoked the fires of a frenzied crisis.

Each of us has a responsibility to verify, or at least use some discretion, before pressing the forward button. There is no race where one has to be first to pass on information. In fact, there is merit in holding back, cross-checking, and then forwarding only if there is credibility in the message. In this instant age, let's not fall for anymore half-baked stories.

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Game Review: State of Decay 2 focuses on the importance of community

When the first State of Decay came out, it was unique in the way that it focused on the survival aspect of a zombie apocalypse rather than the all-out destruction and gore of killing countless zombies. With the new game, the developers have focused their attention on the community aspect of survival.

Right from the start, you get to choose two characters instead of one and each group and character has their own strengths, skills and background. Like the previous game, you can make your posse and build a base of operations complete with a farm and fortification. There are three open world maps — each the size of the map in the original game.

This huge world is littered with empty cabins, new places to build outposts and gather resources. Risky as it may be, the game forces you to explore resources simply because weapons break and you can run out of fuel, food and medical supplies. Venturing out also helps you meet new people to add to the community. State of Decay 2 really hits you home with all the death — losing a built-up human resource can be painful. You can die by getting killed in combat or by way of infection.

Dying in combat is also rare as the AI-controlled characters do a good job of handling themselves, while you take care of business. The only real time you are in danger is when you encounter morbidly obese super zombies that can tear you apart. These guys are tough, but they are the most fun combat you will face in the game, second only to running over zombies with a car, which could have been better if the cars handled better.

Plus, it pays to remember that fuel is a limited resource that you might want to save. Scavenging for resources is fairly simple — if you need fuel, you can raid a gas station; if you need food, find a convenience store or abandoned encampment. Gathered resources can be used to build up, upgrade and fortify your own camp. While there is a ton of stuff to do in the camp and in the surrounding areas, State of Decay 2 does have a main story.

The story mode is a great way to learn about the game and experience various situations as you search for plague hearts to destroy. Plague hearts are throbbing masses of flesh, and it is what produces the infectious plague zombies, identifiable with their glowing eyes. To reduce their numbers, you need to find and destroy the hearts. While the story mode is fulfilling, the camp building and exploring is where the game's strength lies.

We played an advanced copy of the game and the final game will be released on Tuesday. State of Decay 2 still has a lot of bugs, which hopefully will be ironed out soon. Some bugs we encountered on the PC version of the game were floating zombies, breaks in rendering and freezing. This is not a big issue and the developers are sure to patch this over time. And, while the game is very competitively priced, we would recommend waiting for a future bug-free version before jumping in.

State of Decay 2
Rating: 3.5/5
Developer: Undead Labs
Publisher: Microsoft
Platform: PC, XBOX
Price: Rs 1,924

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How you can increase your productivity at work


Lohit Bhatia, CEO of IKYA Human Capital Solutions, a division of Quess Corp, says that at the recruitment end of the business, productivity measures will include how many candidates were lined up as potential candidates for a job, how many were interviewed by the client, how many of these were given the letter and then, finally, how many joined the firm

A few weeks ago, an ad appeared on a premium page of a premium pink paper. The ad, by the homeopathy firm Welcome Cure, with the smiling faces of actors Riteish Deshmukh and Genelia D’Souza was targeted towards corporates, promising help in reducing absenteeism and increasing employee productivity. Chaitanya Choudhury, vice-president corporate relationship at the three-year-old firm with headquarters in Santacruz, says what they provide is a wellness package to employees. At sign up, when the employee’s health ailments are assessed by a Welcome Cure doctor, medicines are designed as per the ailment and sent to the employee on a regular basis at their doorstep.

"Homeopathy also builds immunity, which means that a person falls ill less often. When we sign up with companies, we also assess the specific ailments that professionals from that industry are susceptible to and align the treatment accordingly. If an employee needs special attention, we red flag it and let the HR know. Our doctors are available every day from 9 am to 9 pm. When stress is taken care of, chronic health issues are too. Productivity will naturally improve," adds Choudhury.


Bengaluru-based executive coach Sridhar Laxman conduct six-month-long training sessions where, among other aspects, he helps improve his clients' productivity. An entire training module with him could cost anywhere between Rs 2.5 lakhs to Rs 3.5 lakhs. Pic/Ajeesh F Rawther

The VFM race
In a piece in the Financial Express this April, Neelesh Hundekari, Partner and Head of Leadership, Change & Organisation Practice India, AT Kearney, stated that a study conducted by his firm had found that though Indian businesses have access to one of the largest young and educated workforces in the world, they have not able to make their people as productive as their counterparts across the world. "The revenue per employee in the Indian consumer packaged goods industry — on a PPP-adjusted basis—stood at $64,000, compared to China’s $87,000, South Korea’s $188,000 and the UK’s $287,000. In other words, a UK CPG firm is five times more productive than its Indian counterpart."

Yet, what is productivity? Mohit Gundecha, Co-founder and CEO of the Pune-based data analytics firm Jombay, says: "Many companies confuse productivity with efficiency. Efficiency is ‘getting the same output with less input’, while productivity is ‘getting more output with the same input’." That enhancing employee productivity is a prime objective for companies is easily understood when one sees the reams of research on this. A listicle on bookauthority.com mentions 11 books on the subject, all published only in the last nine months. And this is possibly just the tip of the iceberg. Last week, it was reported that a study published in the Journal of Psychopharmacology, had found that drinking coffee during meetings can lead to a more focussed group discussion, boost involvement and leave members feeling better about everyone’s participation.


Does your company spends too much time on meetings, or do your employees not collaborate well? Call in behavioural scientists Mayur Tekchandaney and Anand Damani who will study your office environment and suggest changes for the desired results. Pic/Ashish Raje

Lohit Bhatia, CEO of IKYA Human Capital Solutions, a division of Quess Corp, puts it down to a simple value-for-money equation. "With every passing year, capital is becoming scarce. And getting higher returns is paramount. Earlier, startups would be flooded with money, but in 2016-17, the money started evaporating. So, every rupee needs to count. After all, someone’s personal wealth is being invested, so it’s important for an outcome to be delivered."

A measure of your work
Where there are deliverables, there are measures to keep count. And, this count has, today, become an important part of the appraisal system that decides your annual increment. An employee at a top multi-national bank says her bonus is partially linked to this performance rating. The sales team, for instance, will be measured against the revenue they bring in, the number of new clients they crack and how many new products are sold. And, an internal software has been built to keep track.


WelcomeCure is a over three-year-old homoeopathy firm that employs over 200 doctors, all available for an online chat or video call between 9 am and 9 pm.

"Each customer has a relationship manager and so, any transaction by them is automatically credited into that manager’s account. At the end of the month, the performance management team will run the reports, check and pass on the information to payroll," says the employee. For those in the wealth management sector, targets include not just getting in more clients but keeping the assets you already have under management and taking care of their wealth.

While transactions are definitely measurable, what about all the work that goes on to make the transaction? The innumerable calls? Bhatia says that at Ikya, where productivity forms close to fifty per cent of the appraisal weightage, every part of the process is measurable. Take for instance, the sales and business development team. "What are the number of sales meetings they have on a daily basis and what is the conversion ratio? If it’s less than five per cent, it’s not constructive for business," he adds. For those involved in the firm’s recruitment end of the business, the numbers that need to add up are: how many candidates were lined up as potential candidates for a job? How many of these were interviewed by customers? What was the success rate i.e. how many of these were given the letter and then, finally, how many joined the firm?


This year, its CEO Punit Desai, started corporate packages which allow firms to extend its service to its employees. An annual package could cost around Rs 12,000 per employee and, says the firm, if the employee leaves the office in the middle of the year, the service still continue till the end of the package. Pics/Sneha Kharabe

Numbers don’t reveal all secrets
Not all jobs can be crunched down in numbers. Karan Khetarpal, director at The Chocolate Spoon Company Pvt. Ltd., which runs the Sassy Spoon chain of restaurants, says that while regular audits can help estimate productivity in different areas of the kitchen, the scope remains limited. "At our central kitchen for instance, we have multiple pastry chefs and here we can calculate their individual outputs. At the restaurant kitchen level, you can monitor wastage and yield of chefs based on inputs such as dairy, poultry and sea food, as well as ordering patterns. There’s an immediate economic impact of what they are doing. For instance, one day we realised that the burgers weren’t available at an outlet because the buns were out of stock. This happened because the kitchen had under ordered the previous day, so it was assessable," says Khetarpal, an investment banker by profession. But, while the sales team may have its targets, it’s not easy to count how many dishes a chef cooked or how many cocktails a particular bartender served. "This is not a factory where you can assess an individual’s productivity. Plus, the turnaround is so high, that the head chef will weed out those not being productive, anyway," he adds.


In January this year, Amazon opened its new office in Seattle with giant glass-and-metal domes filled with tropical and rare plants as a tool to "attract, retain and enhance the productivity and well-being of its fast-growing workforce". The dome took six years of planning and construction.

What the target measure has done, says Bhatia, is bring objectivity into the picture when annual appraisals are done. "There was a time when it was said that in India you got a hike depending on whether your manager liked your face or not. This is becoming a thing of the past because of target measures. Also, there used to be a gap between the organisation’s expectation, what’s being delivered and what the employee thought he was achieving for you. Now there’s an analytical, non-emotional conversation," he adds.

Where does quality fit in? T Muralidharan, founder and chairman of TMI Group, pan India talent and productivity consulting firm, says that output productivity has two key parts — Quantity and Quality. "While quantity is easily measurable, quality is not and hence the supervisor’s judgement comes into the play. In addition quality Vs quality determined by the relative weightage in the goal sheet requires a lot of careful review. Companies have to think a lot more on this. There’s no one-fits-all answer."


Amazon CEO Jeffrey Bezoz. Pics/PTI

The productivity docs
How then does a company improve its productivity? Adopting the latest technology, Gundecha says, is usually the first method. "More intuitive technology tools that work faster and provide analytical support for decision making are a constant demand. Allowing employees flexibility in working schedules is being recognised as a way to boost morale, build loyalty and encourage them to do more for the company." Better health will also mean a better employee.

"An office where every second person has a health issue makes for a depressing environment. However, imagine that your co-workers are all running marathons or climbing mountains. It will keep the environment motivated," says Vishal Gondal, the CEO and founder of GoQii, the fitness tracking firm that also ties up with corporates. Interestingly, for GoQii’s own employees, being fit (or atleast trying to get there) is part of the appraisal process. If you don’t walk an average of 10,000 steps a day or its equivalent, you might immediately be disqualified for assessment.


T Muralidharan, ChairmanTMI Group

Changing the environment
Briefcase is a Khar-based firm run by behavioural scientists Anand Damani and Mayur Tekchandaney. They say they use findings from experiments conducted on real people over the last 50 years to understand how a change in the environment can improve productivity, increase collaboration and motivation. How we sit in offices, says Damani, can impact team collaboration pointing out to the cubicle and workstation system most offices have. "However, when a team sits together on a round table there’s more eye contact and the whole direction is towards each other, employees tend to collaborate more." Are your meetings too long? Damani says replace the chair and tables with a long bar table with everyone standing. "Meetings will end faster since no one wants to stand for long," he says.

And when do they get called in? Damani says it typically begins with issues and problems being faced in the company, such as pace of work being slow or lack of ownership. "It’s the CEO who approaches us. Not the HR. At least not yet. We then find out what is at the heart of the problem." Not just relationship with the management, recognition patterns in the company can also affect productivity. He recalls an employee who’d won the company revenue worth lakhs, being rewarded with a dinner voucher of Rs 5000.


Lohit Bhatia, CEO, IKYA Human Capital Solutions

"The person should also have been made into a hero within the company. His achievement should have been made a case study and showcased to the company’s clients. The process should have been entered into differed awards." While Damani won’t reveal how much they charge the companies for their services, he says it usually takes them a year’s work with the firms. Sometimes, it’s individual training that’s required. This is where Bengaluru-based executive coach Sridhar Laxman steps in. For the last seven years, Laxman has been coaching individuals in what might be simply put as leadership training. Productivity is one component of this. Yet, he argues, when someone learns how to manage stress, not hesitate to take risks, and handle conflict resolution, they will take decisions on the fly easier and show up at work with greater levels of courage. "And when this happens, their productivity will improve."

Signing up with Laxman will cost you between Rs 2.5 lakh and Rs 3.5 lakh. The course is conducted over six to eight months with one hour long sessions every three weeks. Largely, up until now, he says, it’s been firms who have hired him to work with individual employees. It’s only in the last financial year, says Laxman, that 40 per cent of his clientele has been individuals seeking him out on their own. And what could you learn to do under his guidance? Firstly the ability to say no. "Many people struggle around it. They hesitate, fearing that if they say no, they will not be seen as effective contributors. However, saying no conveys that you understand that you have certain priorities now. And there’s no point taking on task six when those on priority one and and two need your immediate attention."