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Realizing the gains and losses in <i>C9ORF72</i> ALS/FTD




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Why It's So Hard to Junk Bad Decisions—Edging Closer to Understanding “Sunk Cost”

Humans, rats and mice all exhibit the decision-making phenomenon, but new research suggests not all choices are equally vulnerable to it




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Recruitment for director and research principal investigators of Shanghai Key Laboratory of Tissue Engineering Research, at Shanghai Ninth People's Hospital, Shanghai Jiao Tong University

Position
Laboratory director and independent principal investigators

Employer
Shanghai Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine

Location
639 Zhi Zao Ju Rd, Huang Pu District, 200011, Shanghai, China

Discipline
Tissue engineering and regenerative medicine related disciplines including: Stem Cell, Developmental Biology, Biomaterials, Biomedical Engineering

Aim:
Shanghai Tissue Engineering Key Laboratory is among the l…




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Early assessment of <i>KRAS</i> mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer




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Exogenous hormone use, reproductive factors and risk of intrahepatic cholangiocarcinoma among women: results from cohort studies in the Liver Cancer Pooling Project and the UK Biobank




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Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




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A single-centre investigator-blinded randomised parallel-group study protocol to investigate the influence of an acclimatisation appointment on children’s behaviour during N<sub>2</sub>O/O<sub>2</sub> sedation as measured by psycho




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Author Correction: Genetic circuit design automation for the gut resident species <i>Bacteroides thetaiotaomicron</i>




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Clinical utility of the exosome based ExoDx Prostate(<i>IntelliScore</i>) EPI test in men presenting for initial Biopsy with a PSA 2–10 ng/mL




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Effect of simulated microgravity on the antidiabetic properties of wheatgrass (<i>Triticum aestivum</i>) in streptozotocin-induced diabetic rats

npj Microgravity, Published online: 24 February 2020; doi:10.1038/s41526-020-0096-x

Effect of simulated microgravity on the antidiabetic properties of wheatgrass (Triticum aestivum) in streptozotocin-induced diabetic rats




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Thermophysical properties of a Si<sub>50</sub>Ge<sub>50</sub> melt measured on board the International Space Station

npj Microgravity, Published online: 25 March 2020; doi:10.1038/s41526-020-0100-5

Thermophysical properties of a Si50Ge50 melt measured on board the International Space Station




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Cellular thermal shift assay for the identification of drug–target interactions in the <i>Plasmodium falciparum</i> proteome




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Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&amp;T-seq




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Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in <i>Drosophila</i>




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Short-term NAD<sup>+</sup> supplementation prevents hearing loss in mouse models of Cockayne syndrome




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LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression




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Cell Death & Disease




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Genocea's mark on malaria

Genocea has identified an immunological imprint in patients with malaria and is using a $1.2 million grant from the Gates Foundation to turn the findings into a vaccine.




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Bridging naïve and primed pluripotency




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Nature Reviews Gastroenterology & Hepatology




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Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear




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Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial




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New insights into K<sub>ATP</sub> channel gene mutations and neonatal diabetes mellitus




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A standardized patient-centered characterization of the phenotypic spectrum of <i>PCDH19</i> girls clustering epilepsy




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Erythrocytosis with <i>JAK2</i> GGCC_46/1 haplotype and without <i>JAK2</i> V617F mutation is associated with <i>CALR</i> rs1049481_G allele




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Peter Ward: 'Membership organisations can thrive and prosper'




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You're invited to an online congress




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COVID-19's Painful Lesson About Strategy and Power

Joseph Nye writes that while trade wars have set back economic globalization,  the environmental globalization represented by pandemics and climate change is unstoppable. Borders are becoming more porous to everything from drugs to infectious diseases to cyber terrorism, and the United States must use its soft power of attraction to develop networks and institutions that address these new threats.




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There's No Such Thing as Good Liberal Hegemony

Stephen Walt argues that as democracies falter, it's worth considering whether the United States made the right call in attempting to create a liberal world order.




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Poll: What the American Public Likes and Hates about Trump's Nuclear Policies

The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons.




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Oil's Collapse Is a Geopolitical Reset In Disguise

The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets.  




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Romney's Reckless China Rhetoric Risks New Cold War

Rachel Esplin Odell argues for a wiser and more conservative strategy that resists the temptation to exaggerate the challenge posed by China.




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Maxwell Taylor's Cold War: From Berlin to Vietnam

Nathaniel Moir reviews Maxwell Taylor's Cold War: From Berlin to Vietnam by Ingo Trauschweizer.




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Julius Weitzdörfer: Managing the Impact of Nuclear Disasters

Julius Weitzdörfer’s earliest childhood memories are the major global events of 1986—the Space Shuttle Challenger explosion and the Chernobyl disaster. Looking back, he realizes that these events must have contributed to shaping his later research interests in managing technological risks. 




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The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing

The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions.




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There's No Such Thing as Good Liberal Hegemony

Stephen Walt argues that as democracies falter, it's worth considering whether the United States made the right call in attempting to create a liberal world order.




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Poll: What the American Public Likes and Hates about Trump's Nuclear Policies

The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons.




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What I Wish I Had Said on CNN About Trump's 'Lysol and Sunshine' Speech

Joel Clement appeared on CNN's Erin Burnett OutFront on April 23, 2020.  In this blog post for the Union of Concerned Scientists, he elaborates on what he wishes he had said during that interview.




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U.S. Intervention in Russia-Saudi Impasse Isn't Tenable (Radio)

Meghan L. O’Sullivan, Professor of International Affairs at Harvard’s Kennedy School, former National Security Council advisor, and a Bloomberg Opinion columnist, discusses the oil market plunge, and the Russia-Saudi relationship. Hosted by Lisa Abramowicz and Paul Sweeney.




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The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing

The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions.




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Oil's Collapse Is a Geopolitical Reset In Disguise

The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets.  




&

The Global Pandemic Has Spawned New Forms of Activism — and They're Flourishing

The authors have identified nearly 100 distinct methods of nonviolent action that include physical, virtual and hybrid actions.




&

There's No Such Thing as Good Liberal Hegemony

Stephen Walt argues that as democracies falter, it's worth considering whether the United States made the right call in attempting to create a liberal world order.




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Poll: What the American Public Likes and Hates about Trump's Nuclear Policies

The authors conducted a study which highlights how the U.S. public as a whole and various demographic groups view President Donald Trump's positions on nuclear weapons.




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What I Wish I Had Said on CNN About Trump's 'Lysol and Sunshine' Speech

Joel Clement appeared on CNN's Erin Burnett OutFront on April 23, 2020.  In this blog post for the Union of Concerned Scientists, he elaborates on what he wishes he had said during that interview.




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Author Correction: <i>Cdkn1a</i> deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation




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Biallelic mutations in <i>SORD</i> cause a common and potentially treatable hereditary neuropathy with implications for diabetes




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Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca<sup>2+</sup> channel internalization in mesenchymal stem cells




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Centros de documentación de diarios en el siglo XXI. Panorama después del tsunami

Guallar, Javier and Cornet, Anna Centros de documentación de diarios en el siglo XXI. Panorama después del tsunami. BiD, 2020, n. 44. [Journal article (Unpaginated)]