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Controlling CAR-T: How scientists plan to make the engineered T cell therapy safer, and work for more cancers

CAR T-cell therapy works wonders for some cancer patients. For others, it is a death sentence. To make the revolutionary therapy work for more people, scientists must devise better ways to control it




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William Sandford Durrell




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Sarepta acquires five muscular dystrophy gene therapies from Myonexus




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U.S. Army bioengineer develops high-tech fabrics to keep soldiers warm, dry, and safe

Paola D’Angelo discusses how her team develops high-performance textiles to protect and support soldiers on the battlefield




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Massive Attack’s space-age anniversary and an out-of-this-world vista




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EPA revises Obama-era industrial safety regulation

Updated following the West, Texas, fertilizer explosion, rule is intended to prevent incidents at facilities handling large amounts of hazardous materials




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Chemical Safety Board chair to resign

Move will leave agency with three of five board members




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Chemical Safety Board chair to resign

Move will leave agency with 3 of 5 board members




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Harcros plans specialties in Saudi Arabia




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Chemical Safety Board finalizes investigation into Arkema fires following Tropical Storm Harvey

Agency urges the chemical industry to better prepare for extreme weather




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EPA revises Obama-era industrial safety regulation

Updated following the West, Texas, fertilizer explosion, rule is intended to prevent incidents at facilities handling large amounts of hazardous materials




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Overhaul of scientific incentives needed to fix Ph.D. system, report says

National Academies committee calls for more emphasis on career counseling, teaching, and mentoring for grad students




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Avara advances in dosage form business with third buy




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U.S. clears Bayer’s acquisition of Monsanto




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Sadara plans pipeline for ethylene and propylene oxide




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Scientists push back against Trump administration’s proposed visa rules




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Chemical Safety Board finalizes investigation into Arkema fires following Tropical Storm Harvey

Agency urges the chemical industry to better prepare for extreme weather




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To shrink electronics further, innovative chemical deposition methods may save the day

Researchers experiment with area-selective atomic layer deposition to precisely place layers of conducting and insulating materials within circuits




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U.S. Chemical Safety Board’s internal woes could thwart its mission




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Sexual harassment pervasive in science, National Academies study says

Cultural change needed to prevent injury to female faculty, students




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Kristen Kulinowski to lead Chemical Safety Board




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Sanofi and Translate Bio to make mRNA vaccines for infectious diseases




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WuXi invests $60 million in Massachusetts




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Chemists synthesize Saturn-shaped molecule

Flat, macrocyclic host captures fullerene guest with CH–π interactions




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Setup may make transferring <em>tert</em>-butyl lithium and other pyrophoric reagents safer

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting




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Sarepta’s Duchenne gene therapy shows promise in small study

The early peek at data from a Phase I/II study excited families, physicians, and investors 




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U.S. report proposes lower safe level for perfluorochemical exposure

ATSDR daily dose numbers for PFOS and PFOA are one-tenth those of EPA




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Recipharm acquires Sanofi’s inhalation assets




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Setup may make transferring <i>tert</i>-butyl lithium and other pyrophoric reagents safer

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting




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Changes on tap at U.S. Chemical Safety Board

Chair departs, investigators leave, staff fears changing mission




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Evonik cuts jobs in cost savings




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A safety net for your many liability risks




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EC investigates sale of Solvay’s nylon unit to BASF




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Heat-stable peptide might save thousands of mothers from excessive bleeding after childbirth

Massive clinical trial including developing nations demonstrates carbetocin is no less effective or safe than oxytocin




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India must change how it evaluates researchers, Indian National Science Academy says




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BASF resumes some vitamin sales after plant fire




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Leading the chemical safety landscape




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Regulus cuts jobs after oligonucleotide safety setback




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Linde, Praxair ready second industrial gas sale




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Changes on tap at U.S. Chemical Safety Board

Chair departs, investigators leave, staff fears changing mission




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Sanofi pays $50 million for Revolution Medicines’ SHP2 inhibitor

The partners expect to begin clinical studies of the compound later this year




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Deadly blast in China highlights uneven enforcement of safety regulations

Facilities where 19 died had not been inspected or approved




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Switchable solvent could save potato chip bags from the trash

Approach dissolves adhesive polymers and recovers bags’ multiple components




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Leading change through a culture of safety




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Cambrex to acquire dosage-form drug contractor Halo

With purchase, manufacturer of active pharmaceutical ingredients will move downstream into finished drugs




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Hope and skepticism abound around Biogen and Eisai Alzheimer’s trial

An antibody called BAN2401 cleared amyloid-β proteins and slowed cognitive decline in people with mild Alzheimer’s disease




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Sangamo acquires TxCell for cell therapy




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Sandra Rosenthal wins Herty Award




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Cambrex to acquire dosage-form drug contractor Halo

With purchase, manufacturer of active pharmaceutical ingredients will move downstream into finished drugs




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BASF to supply human milk oligosaccharide