Bob Iaccino, Path Trading Partners

An Ontario court has declined to review a decision to deny Peter Nygard bail while the former fashion mogul appeals his sexual assault convictions and sentence.

Two buildings collapsed on Hamilton’s Gore Park early Monday morning after being boarded up for over a decade. The fire department says no one was injured and the city has issued an emergency demolition order.

A Mississauga couple is in the midst of a war of words with their townhouse complex's board of directors — which a handful of residents say is imposing unnecessarily strict new rules on the complex's roughly 140 homeowners.

Striking Brampton city workers paused their picket lines on Monday to show respect for war veterans and that means public transit buses in the city ran on their usual schedules without disruption.

One person is dead after a motorcycle and an SUV collided in Mount Albert, Ont., on Monday, Ontario Provincial Police say.

The number of visits to food banks in Toronto hit a new record once again, marking a continuation of a drastic rise in food bank use since the pandemic as Torontonians struggle keeping up with the rising cost of living.

The Ontario Liberal Party is pledging to reduce the income tax rate for middle class families and eliminate provincial sales tax on hydro bills, if they win in the 2026 election.

Statistics Canada data reviewed by CBC Toronto shows a dramatic shift in criminal outcomes in Ontario over the last decade. The majority of criminal cases in the province have ended with charges being withdrawn, stayed, dismissed or discharged before a decision at trial since 2020.

The Toronto Police Services Board unanimously approved a new five-year hiring plan for the force on Tuesday.

Brampton has reached a tentative deal with nearly 1,200 city workers who have been on strike since last week, according to Mayor Patrick Brown and the union.

Sgt. Harman Dhaliwal, who is from Calgary, says he's proud to be a part of the growing exhibit that highlights the relationship between the Sikh faith and military service.

Some Ukrainians living in Calgary say they're even more worried for their friends and family back home in light of Donald Trump's election win.

The provincial government is seeking contractors to restore hundreds of kilometres of land where fireguards were created during the 2023 wildfire season.

The Calgary-based team beat Hamilton Forge FC in a 2-1 nail-biter at home on Saturday, in front of a sold-out crowd of over 7,000 fans at Spruce Meadows.

New rebuilding regulations in Jasper have been approved, but roadblocks — including the sheer number of people that are needed for construction — are popping up.

After Canada Post workers gave a 72-hour notice to strike early Tuesday, some Calgary business owners are worried about what this means for holiday season sales. 

Charlottetown-born curler Brett Gallant says competing in the Olympics will be a dream come true for him and his fiancée, Jocelyn Peterman, even if COVID-19 protocols will make it difficult for them to see each other.

Brad Gushue, Mark Nichols, Brett Gallant and Geoff Walker discuss their team dynamics and what gives them the edge heading into the Beijing Olympics.

After COVID-19 challenges forced the cancellation of Canada's mixed doubles trials, several top curlers are anxiously waiting to learn whether they will be chosen to represent the country in the discipline at the Beijing Games.

The cancellation of the mixed doubles curling trials has generated a wide variety of emotions among players — illuminating a handful of issues, particularly about scheduling and the selection process as a whole.

Kamloops, B.C., has been selected as the host city of the 2023 Scotties Tournament of Hearts.

Laura Walker made a game-winning draw Sunday afternoon to win the Alberta women's curling playdowns and secure a berth in the upcoming national championship.

The oft-discussed wild-card setup at the national championships took centre stage again Monday with the release of updated rankings that appeared to determine the play-in game matchup at the Scotties Tournament of Hearts.

Curling Canada, with the assistance of Own the Podium and the Canadian Olympic Committee, announced Rachel Homan and John Morris as the mixed doubles team for Canada competing at the Beijing Olympics.

Now that all of Canada's Olympic curling teams are finally set, CBC Sports' daily newsletter takes a look at the three tournaments.

Rachel Homan and John Morris weren't the only ones celebrating after their selection to wear the Maple Leaf in mixed doubles curling competition at the Beijing Olympics. The nomination also cleared the path for Team Hollie Duncan to represent Ontario at the national championship.

Newly announced mixed doubles duo Rachel Homan and John Morris, skips Jennifer Jones and Brad Gushue, and broadcasters Mike Harris, Joanne Courtney and Bruce Rainnie all break down a busy week in curling news.

Curling Canada says the Scotties Tournament of Hearts in Thunder Bay, Ont., will operate under Ontario's current public health measures and an approved framework from the office of the chief medical officer.

CME Group, the world's leading derivatives marketplace, today announced its new CBL Australian Carbon Credit Unit (ACCU) futures have launched and are available for trading. A total of five...

CME Group, the world's leading derivatives marketplace, today announced it has received approval from the National Futures Association (NFA) to establish a futures commission merchant (FCM). "We...

CME Group, the world's leading derivatives marketplace, today announced that open interest in its global benchmark Henry Hub futures contract reached a record 1.73 million contracts on October 30,...

Record October ADV for interest rate, energy, metals and agricultural products Record October ADV across U.S. Treasury and SOFR complexes All-time record monthly ADV in U.S. Treasury options and...

Farmer sentiment saw an unexpected surge in October ahead of the upcoming U.S. election, according to the latest Purdue University/CME Group Ag Economy Barometer. The index rose to 115, marking a...

A researcher may have many reasons for wanting to establish new laboratory colonies from field-collected mosquitoes. In particular, the ability to study the diversity found within and among natural populations in a controlled laboratory environment opens up a wide range of possibilities for understanding how and why burdens of vector-borne disease vary over space and time. However, field-collected mosquitoes are often more difficult to work with than established laboratory strains, and considerable logistical challenges are involved in safely transporting field-collected mosquitoes into the laboratory. Here, we provide advice for researchers working with Aedes aegypti, Anopheles gambiae, and Culex pipiens, as well as notes on other closely related species. We provide guidance on each stage of the life cycle and highlight the life stages for which it is easiest to initiate new laboratory colonies for each species. In accompanying protocols, we provide methods detailing Ae. aegypti egg collection and hatching as well as how to transport larvae and pupae from the field.

Sleep is likely a whole-brain phenomenon, with most of the brain probably benefiting from this state of decreased arousal. Recent advances in our understanding of some potential sleep functions, such as metabolite clearance and synaptic homeostasis, make it evident why the whole brain is likely impacted by sleep: All neurons have synapses, and all neurons produce waste metabolites. Sleep experiments in the fly Drosophila melanogaster suggest that diverse sleep functions appear to be conserved across all animals. Studies of brain activity during sleep in humans typically involve multidimensional data sets, such as those acquired by electroencephalograms (EEGs) or functional magnetic resonance imaging (fMRI), and these whole-brain read-outs often reveal important qualities of different sleep stages, such as changes in frequency dynamics or connectivity. Recently, various techniques have been developed that allow for the recording of neural activity simultaneously across multiple regions of the fly brain. These whole-brain-recording approaches will be important for better understanding sleep physiology and function, as they provide a more comprehensive view of neural dynamics during sleep and wake in a relevant model system. Here, we present a brief summary of some of the findings derived from sleep activity recording studies in sleeping Drosophila flies and discuss the value of electrophysiological versus calcium imaging techniques. Although these involve very different preparations, they both highlight the value of multidimensional data for studying sleep in this model system, like the use of both EEG and fMRI in humans.

The establishment of neural connectivity is a major part of neural development. The central nervous system (CNS) midline is the most characterized axon guidance choice point, and work in Drosophila has played a pivotal role in understanding the molecular mechanisms responsible. Axons respond to attractive cues such as Netrin via the Frazzled receptor, and repulsive cues such as Slit via Robo receptors. Both signals are expressed at the CNS midline, affect pioneer axons, and have dramatic effects on the axon scaffold as a whole. Here, we focus on previous research analyzing classic mutants in the Slit/Robo pathway, which can readily be detected with a dissecting microscope. We also discuss analyzing these mutants in a teaching lab situation. The combination of sophisticated genetics and reliable axonal markers in Drosophila allows phenotypic analysis to be performed at the single-cell level. The elaborate architecture of neurons is very sensitive to disruption by genetic mutations, allowing the effects of novel mutations to be easily detected and assessed.

The host associations of mosquitoes vary by species, with some species being relative generalists, whereas others specialize, to varying extents, on a particular subset of the available host community. These host associations are driving factors in transmission dynamics of mosquito-vectored pathogens. For this reason, characterizing the host associations of mosquito species is critical for understanding the epidemiology of mosquito-vectored pathogens. Diverse methods have been used to associate mosquito species with their hosts. These typically include collecting mosquitoes that bite a restrained host (bait) or collecting wild blood-engorged mosquitoes and matching their blood meal to reference samples (blood meal analysis). Blood meal analysis refers to a collection of molecular techniques for determining the taxonomic identity of the source of a mosquito blood meal using cytological, serological, or DNA-based characteristics of the blood meal. Blood meal analyses that are based on DNA markers have advantages over cytological and serological methods and are effective for determining species-level identities of hosts from a broad range of potential host taxa. Here, we discuss effective techniques for analyzing blood meals.

OM Montenegro put on a two week Beach Outreach in the city of Bar.

No public playground exists in Bar, Montenegro. This year, OM Montenegro plans to build one with the help of an outreach team.

She only came for a week, but impacted lives of several families with children with autism. Isabel Black shares about her experiences in Montenegro.

Four volunteers from Switzerland. One empty park. Ten days to build a playground. Could it be done?

An OM couple serving in Bar, Montenegro share how a short-term team building a shelter has had positive and lasting impact on a community they serve through a club for kids.

Mozaik church, pioneered by the OM team in Bar, Montenegro, has recently baptised seven new believers in the Adriatic sea, at the beach.

Can young people be united in faith, irrespective of their ethnic background? The answer is yes!

Even if things don't go quite to plan, the kids' craft sessions at OM Montenegro's Lighthouse centre result in wonderful presents for families.

After making friends at OM's English Cafe, Igor shares with them how he came from a similar background but was freed from despair when he met Jesus.

OMers visit the beachfront cafes for weekly Bible study, seeking to bless the businesses and share God's love all year round.