of Biology and physiology of freshwater neotropical fishes By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9780128158739 (electronic bk.) Full Article
of Biology and ecology of venomous marine cnidarians By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Santhanam, Ramasamy, 1946- authorCallnumber: OnlineISBN: 9789811516030 (electronic bk.) Full Article
of Biodiversity of the Himalaya : Jammu and Kashmir State By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9789813291744 (electronic bk.) Full Article
of Beyond our genes : pathophysiology of gene and environment interaction and epigenetic inheritance By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783030352134 (electronic bk.) Full Article
of Atlas of ulcers in systemic sclerosis : diagnosis and management By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319984773 (electronic bk.) Full Article
of Atlas of sexually transmitted diseases : clinical aspects and differential diagnosis By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319574707 (electronic bk.) Full Article
of Atlas of mohs and frozen section cutaneous pathology By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319748474 978-3-319-74847-4 Full Article
of Atlas of male genital dermatology By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Hall, Anthony, author.Callnumber: OnlineISBN: 9783319997506 (electronic bk.) Full Article
of Atlas of Lymphatic System in Cancer By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Gantsev, Shamil. author. aut http://id.loc.gov/vocabulary/relators/autCallnumber: OnlineISBN: 9783030409678 978-3-030-40967-8 Full Article
of Atlas of Lasers and Lights in Dermatology By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Cannarozzo, Giovanni. author.Callnumber: OnlineISBN: 9783030312329 Full Article
of Arctic plants of Svalbard : what we learn from the green in the treeless white world By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Lee, Yoo Kyung, authorCallnumber: OnlineISBN: 9783030345600 (electronic bk.) Full Article
of Anomalies of the Developing Dentition : a Clinical Guide to Diagnosis and Management By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Soxman, Jane A., author.Callnumber: OnlineISBN: 9783030031640 (electronic bk.) Full Article
of Anatomical chart company atlas of pathophysiology By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Atlas of pathophysiology.Callnumber: OnlineISBN: 9781496370921 Full Article
of Anaerobic utilization of hydrocarbons, oils, and lipids By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319503912 (electronic bk.) Full Article
of An encyclopaedia of British bridges By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: McFetrich, David, author.Callnumber: OnlineISBN: 9781526752963 (electronic bk.) Full Article
of African edible insects as alternative source of food, oil, protein and bioactive components By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783030329525 (electronic bk.) Full Article
of A handbook of nuclear applications in humans' lives By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Tabbakh, Farshid, author.Callnumber: OnlineISBN: 9781527544512 (electronic bk.) Full Article
of Notice of Construction - Kennedy Rd. and Ravenshoe Rd. By www.eastgwillimbury.ca Published On :: Sun, 03 May 2020 16:28:03 GMT Full Article
of Notice of Construction - Woodbine Ave. By www.eastgwillimbury.ca Published On :: Fri, 24 Apr 2020 18:41:27 GMT Full Article
of Suntuity AirWorks Offering FREE Assistance in Drone Acquisition... By www.prweb.com Published On :: The drones and programs will be fully paid for by the DOJ as part of the $850 million funding that has been allocated to help public safety departments fight the spread of COVID-19. This includes...(PRWeb April 30, 2020)Read the full story at https://www.prweb.com/releases/suntuity_airworks_offering_free_assistance_in_drone_acquisition_through_850mm_federal_grant_assistance_program_for_public_safety_agencies/prweb17090555.htm Full Article
of Penalized generalized empirical likelihood with a diverging number of general estimating equations for censored data By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Niansheng Tang, Xiaodong Yan, Xingqiu Zhao. Source: The Annals of Statistics, Volume 48, Number 1, 607--627.Abstract: This article considers simultaneous variable selection and parameter estimation as well as hypothesis testing in censored survival models where a parametric likelihood is not available. For the problem, we utilize certain growing dimensional general estimating equations and propose a penalized generalized empirical likelihood, where the general estimating equations are constructed based on the semiparametric efficiency bound of estimation with given moment conditions. The proposed penalized generalized empirical likelihood estimators enjoy the oracle properties, and the estimator of any fixed dimensional vector of nonzero parameters achieves the semiparametric efficiency bound asymptotically. Furthermore, we show that the penalized generalized empirical likelihood ratio test statistic has an asymptotic central chi-square distribution. The conditions of local and restricted global optimality of weighted penalized generalized empirical likelihood estimators are also discussed. We present a two-layer iterative algorithm for efficient implementation, and investigate its convergence property. The performance of the proposed methods is demonstrated by extensive simulation studies, and a real data example is provided for illustration. Full Article
of Almost sure uniqueness of a global minimum without convexity By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Gregory Cox. Source: The Annals of Statistics, Volume 48, Number 1, 584--606.Abstract: This paper establishes the argmin of a random objective function to be unique almost surely. This paper first formulates a general result that proves almost sure uniqueness without convexity of the objective function. The general result is then applied to a variety of applications in statistics. Four applications are discussed, including uniqueness of M-estimators, both classical likelihood and penalized likelihood estimators, and two applications of the argmin theorem, threshold regression and weak identification. Full Article
of Asymptotic genealogies of interacting particle systems with an application to sequential Monte Carlo By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Jere Koskela, Paul A. Jenkins, Adam M. Johansen, Dario Spanò. Source: The Annals of Statistics, Volume 48, Number 1, 560--583.Abstract: We study weighted particle systems in which new generations are resampled from current particles with probabilities proportional to their weights. This covers a broad class of sequential Monte Carlo (SMC) methods, widely-used in applied statistics and cognate disciplines. We consider the genealogical tree embedded into such particle systems, and identify conditions, as well as an appropriate time-scaling, under which they converge to the Kingman $n$-coalescent in the infinite system size limit in the sense of finite-dimensional distributions. Thus, the tractable $n$-coalescent can be used to predict the shape and size of SMC genealogies, as we illustrate by characterising the limiting mean and variance of the tree height. SMC genealogies are known to be connected to algorithm performance, so that our results are likely to have applications in the design of new methods as well. Our conditions for convergence are strong, but we show by simulation that they do not appear to be necessary. Full Article
of Markov equivalence of marginalized local independence graphs By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Søren Wengel Mogensen, Niels Richard Hansen. Source: The Annals of Statistics, Volume 48, Number 1, 539--559.Abstract: Symmetric independence relations are often studied using graphical representations. Ancestral graphs or acyclic directed mixed graphs with $m$-separation provide classes of symmetric graphical independence models that are closed under marginalization. Asymmetric independence relations appear naturally for multivariate stochastic processes, for instance, in terms of local independence. However, no class of graphs representing such asymmetric independence relations, which is also closed under marginalization, has been developed. We develop the theory of directed mixed graphs with $mu $-separation and show that this provides a graphical independence model class which is closed under marginalization and which generalizes previously considered graphical representations of local independence. Several graphs may encode the same set of independence relations and this means that in many cases only an equivalence class of graphs can be identified from observational data. For statistical applications, it is therefore pivotal to characterize graphs that induce the same independence relations. Our main result is that for directed mixed graphs with $mu $-separation each equivalence class contains a maximal element which can be constructed from the independence relations alone. Moreover, we introduce the directed mixed equivalence graph as the maximal graph with dashed and solid edges. This graph encodes all information about the edges that is identifiable from the independence relations, and furthermore it can be computed efficiently from the maximal graph. Full Article
of Averages of unlabeled networks: Geometric characterization and asymptotic behavior By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Eric D. Kolaczyk, Lizhen Lin, Steven Rosenberg, Jackson Walters, Jie Xu. Source: The Annals of Statistics, Volume 48, Number 1, 514--538.Abstract: It is becoming increasingly common to see large collections of network data objects, that is, data sets in which a network is viewed as a fundamental unit of observation. As a result, there is a pressing need to develop network-based analogues of even many of the most basic tools already standard for scalar and vector data. In this paper, our focus is on averages of unlabeled, undirected networks with edge weights. Specifically, we (i) characterize a certain notion of the space of all such networks, (ii) describe key topological and geometric properties of this space relevant to doing probability and statistics thereupon, and (iii) use these properties to establish the asymptotic behavior of a generalized notion of an empirical mean under sampling from a distribution supported on this space. Our results rely on a combination of tools from geometry, probability theory and statistical shape analysis. In particular, the lack of vertex labeling necessitates working with a quotient space modding out permutations of labels. This results in a nontrivial geometry for the space of unlabeled networks, which in turn is found to have important implications on the types of probabilistic and statistical results that may be obtained and the techniques needed to obtain them. Full Article
of Efficient estimation of linear functionals of principal components By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Vladimir Koltchinskii, Matthias Löffler, Richard Nickl. Source: The Annals of Statistics, Volume 48, Number 1, 464--490.Abstract: We study principal component analysis (PCA) for mean zero i.i.d. Gaussian observations $X_{1},dots,X_{n}$ in a separable Hilbert space $mathbb{H}$ with unknown covariance operator $Sigma $. The complexity of the problem is characterized by its effective rank $mathbf{r}(Sigma):=frac{operatorname{tr}(Sigma)}{|Sigma |}$, where $mathrm{tr}(Sigma)$ denotes the trace of $Sigma $ and $|Sigma|$ denotes its operator norm. We develop a method of bias reduction in the problem of estimation of linear functionals of eigenvectors of $Sigma $. Under the assumption that $mathbf{r}(Sigma)=o(n)$, we establish the asymptotic normality and asymptotic properties of the risk of the resulting estimators and prove matching minimax lower bounds, showing their semiparametric optimality. Full Article
of Consistent selection of the number of change-points via sample-splitting By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Changliang Zou, Guanghui Wang, Runze Li. Source: The Annals of Statistics, Volume 48, Number 1, 413--439.Abstract: In multiple change-point analysis, one of the major challenges is to estimate the number of change-points. Most existing approaches attempt to minimize a Schwarz information criterion which balances a term quantifying model fit with a penalization term accounting for model complexity that increases with the number of change-points and limits overfitting. However, different penalization terms are required to adapt to different contexts of multiple change-point problems and the optimal penalization magnitude usually varies from the model and error distribution. We propose a data-driven selection criterion that is applicable to most kinds of popular change-point detection methods, including binary segmentation and optimal partitioning algorithms. The key idea is to select the number of change-points that minimizes the squared prediction error, which measures the fit of a specified model for a new sample. We develop a cross-validation estimation scheme based on an order-preserved sample-splitting strategy, and establish its asymptotic selection consistency under some mild conditions. Effectiveness of the proposed selection criterion is demonstrated on a variety of numerical experiments and real-data examples. Full Article
of Concentration and consistency results for canonical and curved exponential-family models of random graphs By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Michael Schweinberger, Jonathan Stewart. Source: The Annals of Statistics, Volume 48, Number 1, 374--396.Abstract: Statistical inference for exponential-family models of random graphs with dependent edges is challenging. We stress the importance of additional structure and show that additional structure facilitates statistical inference. A simple example of a random graph with additional structure is a random graph with neighborhoods and local dependence within neighborhoods. We develop the first concentration and consistency results for maximum likelihood and $M$-estimators of a wide range of canonical and curved exponential-family models of random graphs with local dependence. All results are nonasymptotic and applicable to random graphs with finite populations of nodes, although asymptotic consistency results can be obtained as well. In addition, we show that additional structure can facilitate subgraph-to-graph estimation, and present concentration results for subgraph-to-graph estimators. As an application, we consider popular curved exponential-family models of random graphs, with local dependence induced by transitivity and parameter vectors whose dimensions depend on the number of nodes. Full Article
of New $G$-formula for the sequential causal effect and blip effect of treatment in sequential causal inference By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Xiaoqin Wang, Li Yin. Source: The Annals of Statistics, Volume 48, Number 1, 138--160.Abstract: In sequential causal inference, two types of causal effects are of practical interest, namely, the causal effect of the treatment regime (called the sequential causal effect) and the blip effect of treatment on the potential outcome after the last treatment. The well-known $G$-formula expresses these causal effects in terms of the standard parameters. In this article, we obtain a new $G$-formula that expresses these causal effects in terms of the point observable effects of treatments similar to treatment in the framework of single-point causal inference. Based on the new $G$-formula, we estimate these causal effects by maximum likelihood via point observable effects with methods extended from single-point causal inference. We are able to increase precision of the estimation without introducing biases by an unsaturated model imposing constraints on the point observable effects. We are also able to reduce the number of point observable effects in the estimation by treatment assignment conditions. Full Article
of The phase transition for the existence of the maximum likelihood estimate in high-dimensional logistic regression By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Emmanuel J. Candès, Pragya Sur. Source: The Annals of Statistics, Volume 48, Number 1, 27--42.Abstract: This paper rigorously establishes that the existence of the maximum likelihood estimate (MLE) in high-dimensional logistic regression models with Gaussian covariates undergoes a sharp “phase transition.” We introduce an explicit boundary curve $h_{mathrm{MLE}}$, parameterized by two scalars measuring the overall magnitude of the unknown sequence of regression coefficients, with the following property: in the limit of large sample sizes $n$ and number of features $p$ proportioned in such a way that $p/n ightarrow kappa $, we show that if the problem is sufficiently high dimensional in the sense that $kappa >h_{mathrm{MLE}}$, then the MLE does not exist with probability one. Conversely, if $kappa <h_{mathrm{MLE}}$, the MLE asymptotically exists with probability one. Full Article
of Detecting relevant changes in the mean of nonstationary processes—A mass excess approach By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Holger Dette, Weichi Wu. Source: The Annals of Statistics, Volume 47, Number 6, 3578--3608.Abstract: This paper considers the problem of testing if a sequence of means $(mu_{t})_{t=1,ldots ,n}$ of a nonstationary time series $(X_{t})_{t=1,ldots ,n}$ is stable in the sense that the difference of the means $mu_{1}$ and $mu_{t}$ between the initial time $t=1$ and any other time is smaller than a given threshold, that is $|mu_{1}-mu_{t}|leq c$ for all $t=1,ldots ,n$. A test for hypotheses of this type is developed using a bias corrected monotone rearranged local linear estimator and asymptotic normality of the corresponding test statistic is established. As the asymptotic variance depends on the location of the roots of the equation $|mu_{1}-mu_{t}|=c$ a new bootstrap procedure is proposed to obtain critical values and its consistency is established. As a consequence we are able to quantitatively describe relevant deviations of a nonstationary sequence from its initial value. The results are illustrated by means of a simulation study and by analyzing data examples. Full Article
of Joint convergence of sample autocovariance matrices when $p/n o 0$ with application By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Monika Bhattacharjee, Arup Bose. Source: The Annals of Statistics, Volume 47, Number 6, 3470--3503.Abstract: Consider a high-dimensional linear time series model where the dimension $p$ and the sample size $n$ grow in such a way that $p/n o 0$. Let $hat{Gamma }_{u}$ be the $u$th order sample autocovariance matrix. We first show that the LSD of any symmetric polynomial in ${hat{Gamma }_{u},hat{Gamma }_{u}^{*},ugeq 0}$ exists under independence and moment assumptions on the driving sequence together with weak assumptions on the coefficient matrices. This LSD result, with some additional effort, implies the asymptotic normality of the trace of any polynomial in ${hat{Gamma }_{u},hat{Gamma }_{u}^{*},ugeq 0}$. We also study similar results for several independent MA processes. We show applications of the above results to statistical inference problems such as in estimation of the unknown order of a high-dimensional MA process and in graphical and significance tests for hypotheses on coefficient matrices of one or several such independent processes. Full Article
of Hypothesis testing on linear structures of high-dimensional covariance matrix By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Shurong Zheng, Zhao Chen, Hengjian Cui, Runze Li. Source: The Annals of Statistics, Volume 47, Number 6, 3300--3334.Abstract: This paper is concerned with test of significance on high-dimensional covariance structures, and aims to develop a unified framework for testing commonly used linear covariance structures. We first construct a consistent estimator for parameters involved in the linear covariance structure, and then develop two tests for the linear covariance structures based on entropy loss and quadratic loss used for covariance matrix estimation. To study the asymptotic properties of the proposed tests, we study related high-dimensional random matrix theory, and establish several highly useful asymptotic results. With the aid of these asymptotic results, we derive the limiting distributions of these two tests under the null and alternative hypotheses. We further show that the quadratic loss based test is asymptotically unbiased. We conduct Monte Carlo simulation study to examine the finite sample performance of the two tests. Our simulation results show that the limiting null distributions approximate their null distributions quite well, and the corresponding asymptotic critical values keep Type I error rate very well. Our numerical comparison implies that the proposed tests outperform existing ones in terms of controlling Type I error rate and power. Our simulation indicates that the test based on quadratic loss seems to have better power than the test based on entropy loss. Full Article
of On partial-sum processes of ARMAX residuals By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Steffen Grønneberg, Benjamin Holcblat. Source: The Annals of Statistics, Volume 47, Number 6, 3216--3243.Abstract: We establish general and versatile results regarding the limit behavior of the partial-sum process of ARMAX residuals. Illustrations include ARMA with seasonal dummies, misspecified ARMAX models with autocorrelated errors, nonlinear ARMAX models, ARMA with a structural break, a wide range of ARMAX models with infinite-variance errors, weak GARCH models and the consistency of kernel estimation of the density of ARMAX errors. Our results identify the limit distributions, and provide a general algorithm to obtain pivot statistics for CUSUM tests. Full Article
of Statistical inference for autoregressive models under heteroscedasticity of unknown form By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Ke Zhu. Source: The Annals of Statistics, Volume 47, Number 6, 3185--3215.Abstract: This paper provides an entire inference procedure for the autoregressive model under (conditional) heteroscedasticity of unknown form with a finite variance. We first establish the asymptotic normality of the weighted least absolute deviations estimator (LADE) for the model. Second, we develop the random weighting (RW) method to estimate its asymptotic covariance matrix, leading to the implementation of the Wald test. Third, we construct a portmanteau test for model checking, and use the RW method to obtain its critical values. As a special weighted LADE, the feasible adaptive LADE (ALADE) is proposed and proved to have the same efficiency as its infeasible counterpart. The importance of our entire methodology based on the feasible ALADE is illustrated by simulation results and the real data analysis on three U.S. economic data sets. Full Article
of Adaptive estimation of the rank of the coefficient matrix in high-dimensional multivariate response regression models By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Xin Bing, Marten H. Wegkamp. Source: The Annals of Statistics, Volume 47, Number 6, 3157--3184.Abstract: We consider the multivariate response regression problem with a regression coefficient matrix of low, unknown rank. In this setting, we analyze a new criterion for selecting the optimal reduced rank. This criterion differs notably from the one proposed in Bunea, She and Wegkamp ( Ann. Statist. 39 (2011) 1282–1309) in that it does not require estimation of the unknown variance of the noise, nor does it depend on a delicate choice of a tuning parameter. We develop an iterative, fully data-driven procedure, that adapts to the optimal signal-to-noise ratio. This procedure finds the true rank in a few steps with overwhelming probability. At each step, our estimate increases, while at the same time it does not exceed the true rank. Our finite sample results hold for any sample size and any dimension, even when the number of responses and of covariates grow much faster than the number of observations. We perform an extensive simulation study that confirms our theoretical findings. The new method performs better and is more stable than the procedure of Bunea, She and Wegkamp ( Ann. Statist. 39 (2011) 1282–1309) in both low- and high-dimensional settings. Full Article
of Distributed estimation of principal eigenspaces By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Jianqing Fan, Dong Wang, Kaizheng Wang, Ziwei Zhu. Source: The Annals of Statistics, Volume 47, Number 6, 3009--3031.Abstract: Principal component analysis (PCA) is fundamental to statistical machine learning. It extracts latent principal factors that contribute to the most variation of the data. When data are stored across multiple machines, however, communication cost can prohibit the computation of PCA in a central location and distributed algorithms for PCA are thus needed. This paper proposes and studies a distributed PCA algorithm: each node machine computes the top $K$ eigenvectors and transmits them to the central server; the central server then aggregates the information from all the node machines and conducts a PCA based on the aggregated information. We investigate the bias and variance for the resulting distributed estimator of the top $K$ eigenvectors. In particular, we show that for distributions with symmetric innovation, the empirical top eigenspaces are unbiased, and hence the distributed PCA is “unbiased.” We derive the rate of convergence for distributed PCA estimators, which depends explicitly on the effective rank of covariance, eigengap, and the number of machines. We show that when the number of machines is not unreasonably large, the distributed PCA performs as well as the whole sample PCA, even without full access of whole data. The theoretical results are verified by an extensive simulation study. We also extend our analysis to the heterogeneous case where the population covariance matrices are different across local machines but share similar top eigenstructures. Full Article
of Testing for independence of large dimensional vectors By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Taras Bodnar, Holger Dette, Nestor Parolya. Source: The Annals of Statistics, Volume 47, Number 5, 2977--3008.Abstract: In this paper, new tests for the independence of two high-dimensional vectors are investigated. We consider the case where the dimension of the vectors increases with the sample size and propose multivariate analysis of variance-type statistics for the hypothesis of a block diagonal covariance matrix. The asymptotic properties of the new test statistics are investigated under the null hypothesis and the alternative hypothesis using random matrix theory. For this purpose, we study the weak convergence of linear spectral statistics of central and (conditionally) noncentral Fisher matrices. In particular, a central limit theorem for linear spectral statistics of large dimensional (conditionally) noncentral Fisher matrices is derived which is then used to analyse the power of the tests under the alternative. The theoretical results are illustrated by means of a simulation study where we also compare the new tests with several alternative, in particular with the commonly used corrected likelihood ratio test. It is demonstrated that the latter test does not keep its nominal level, if the dimension of one sub-vector is relatively small compared to the dimension of the other sub-vector. On the other hand, the tests proposed in this paper provide a reasonable approximation of the nominal level in such situations. Moreover, we observe that one of the proposed tests is most powerful under a variety of correlation scenarios. Full Article
of Inference for the mode of a log-concave density By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Charles R. Doss, Jon A. Wellner. Source: The Annals of Statistics, Volume 47, Number 5, 2950--2976.Abstract: We study a likelihood ratio test for the location of the mode of a log-concave density. Our test is based on comparison of the log-likelihoods corresponding to the unconstrained maximum likelihood estimator of a log-concave density and the constrained maximum likelihood estimator where the constraint is that the mode of the density is fixed, say at $m$. The constrained estimation problem is studied in detail in Doss and Wellner (2018). Here, the results of that paper are used to show that, under the null hypothesis (and strict curvature of $-log f$ at the mode), the likelihood ratio statistic is asymptotically pivotal: that is, it converges in distribution to a limiting distribution which is free of nuisance parameters, thus playing the role of the $chi_{1}^{2}$ distribution in classical parametric statistical problems. By inverting this family of tests, we obtain new (likelihood ratio based) confidence intervals for the mode of a log-concave density $f$. These new intervals do not depend on any smoothing parameters. We study the new confidence intervals via Monte Carlo methods and illustrate them with two real data sets. The new intervals seem to have several advantages over existing procedures. Software implementing the test and confidence intervals is available in the R package verb+logcondens.mode+. Full Article
of Projected spline estimation of the nonparametric function in high-dimensional partially linear models for massive data By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Heng Lian, Kaifeng Zhao, Shaogao Lv. Source: The Annals of Statistics, Volume 47, Number 5, 2922--2949.Abstract: In this paper, we consider the local asymptotics of the nonparametric function in a partially linear model, within the framework of the divide-and-conquer estimation. Unlike the fixed-dimensional setting in which the parametric part does not affect the nonparametric part, the high-dimensional setting makes the issue more complicated. In particular, when a sparsity-inducing penalty such as lasso is used to make the estimation of the linear part feasible, the bias introduced will propagate to the nonparametric part. We propose a novel approach for estimation of the nonparametric function and establish the local asymptotics of the estimator. The result is useful for massive data with possibly different linear coefficients in each subpopulation but common nonparametric function. Some numerical illustrations are also presented. Full Article
of Eigenvalue distributions of variance components estimators in high-dimensional random effects models By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Zhou Fan, Iain M. Johnstone. Source: The Annals of Statistics, Volume 47, Number 5, 2855--2886.Abstract: We study the spectra of MANOVA estimators for variance component covariance matrices in multivariate random effects models. When the dimensionality of the observations is large and comparable to the number of realizations of each random effect, we show that the empirical spectra of such estimators are well approximated by deterministic laws. The Stieltjes transforms of these laws are characterized by systems of fixed-point equations, which are numerically solvable by a simple iterative procedure. Our proof uses operator-valued free probability theory, and we establish a general asymptotic freeness result for families of rectangular orthogonally invariant random matrices, which is of independent interest. Our work is motivated in part by the estimation of components of covariance between multiple phenotypic traits in quantitative genetics, and we specialize our results to common experimental designs that arise in this application. Full Article
of A unified treatment of multiple testing with prior knowledge using the p-filter By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Aaditya K. Ramdas, Rina F. Barber, Martin J. Wainwright, Michael I. Jordan. Source: The Annals of Statistics, Volume 47, Number 5, 2790--2821.Abstract: There is a significant literature on methods for incorporating knowledge into multiple testing procedures so as to improve their power and precision. Some common forms of prior knowledge include (a) beliefs about which hypotheses are null, modeled by nonuniform prior weights; (b) differing importances of hypotheses, modeled by differing penalties for false discoveries; (c) multiple arbitrary partitions of the hypotheses into (possibly overlapping) groups and (d) knowledge of independence, positive or arbitrary dependence between hypotheses or groups, suggesting the use of more aggressive or conservative procedures. We present a unified algorithmic framework called p-filter for global null testing and false discovery rate (FDR) control that allows the scientist to incorporate all four types of prior knowledge (a)–(d) simultaneously, recovering a variety of known algorithms as special cases. Full Article
of The middle-scale asymptotics of Wishart matrices By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Didier Chételat, Martin T. Wells. Source: The Annals of Statistics, Volume 47, Number 5, 2639--2670.Abstract: We study the behavior of a real $p$-dimensional Wishart random matrix with $n$ degrees of freedom when $n,p ightarrowinfty$ but $p/n ightarrow0$. We establish the existence of phase transitions when $p$ grows at the order $n^{(K+1)/(K+3)}$ for every $Kinmathbb{N}$, and derive expressions for approximating densities between every two phase transitions. To do this, we make use of a novel tool we call the $mathcal{F}$-conjugate of an absolutely continuous distribution, which is obtained from the Fourier transform of the square root of its density. In the case of the normalized Wishart distribution, this represents an extension of the $t$-distribution to the space of real symmetric matrices. Full Article
of Semi-supervised inference: General theory and estimation of means By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Anru Zhang, Lawrence D. Brown, T. Tony Cai. Source: The Annals of Statistics, Volume 47, Number 5, 2538--2566.Abstract: We propose a general semi-supervised inference framework focused on the estimation of the population mean. As usual in semi-supervised settings, there exists an unlabeled sample of covariate vectors and a labeled sample consisting of covariate vectors along with real-valued responses (“labels”). Otherwise, the formulation is “assumption-lean” in that no major conditions are imposed on the statistical or functional form of the data. We consider both the ideal semi-supervised setting where infinitely many unlabeled samples are available, as well as the ordinary semi-supervised setting in which only a finite number of unlabeled samples is available. Estimators are proposed along with corresponding confidence intervals for the population mean. Theoretical analysis on both the asymptotic distribution and $ell_{2}$-risk for the proposed procedures are given. Surprisingly, the proposed estimators, based on a simple form of the least squares method, outperform the ordinary sample mean. The simple, transparent form of the estimator lends confidence to the perception that its asymptotic improvement over the ordinary sample mean also nearly holds even for moderate size samples. The method is further extended to a nonparametric setting, in which the oracle rate can be achieved asymptotically. The proposed estimators are further illustrated by simulation studies and a real data example involving estimation of the homeless population. Full Article
of A knockoff filter for high-dimensional selective inference By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Rina Foygel Barber, Emmanuel J. Candès. Source: The Annals of Statistics, Volume 47, Number 5, 2504--2537.Abstract: This paper develops a framework for testing for associations in a possibly high-dimensional linear model where the number of features/variables may far exceed the number of observational units. In this framework, the observations are split into two groups, where the first group is used to screen for a set of potentially relevant variables, whereas the second is used for inference over this reduced set of variables; we also develop strategies for leveraging information from the first part of the data at the inference step for greater power. In our work, the inferential step is carried out by applying the recently introduced knockoff filter, which creates a knockoff copy—a fake variable serving as a control—for each screened variable. We prove that this procedure controls the directional false discovery rate (FDR) in the reduced model controlling for all screened variables; this says that our high-dimensional knockoff procedure “discovers” important variables as well as the directions (signs) of their effects, in such a way that the expected proportion of wrongly chosen signs is below the user-specified level (thereby controlling a notion of Type S error averaged over the selected set). This result is nonasymptotic, and holds for any distribution of the original features and any values of the unknown regression coefficients, so that inference is not calibrated under hypothesized values of the effect sizes. We demonstrate the performance of our general and flexible approach through numerical studies, showing more power than existing alternatives. Finally, we apply our method to a genome-wide association study to find locations on the genome that are possibly associated with a continuous phenotype. Full Article
of Convergence complexity analysis of Albert and Chib’s algorithm for Bayesian probit regression By projecteuclid.org Published On :: Tue, 21 May 2019 04:00 EDT Qian Qin, James P. Hobert. Source: The Annals of Statistics, Volume 47, Number 4, 2320--2347.Abstract: The use of MCMC algorithms in high dimensional Bayesian problems has become routine. This has spurred so-called convergence complexity analysis, the goal of which is to ascertain how the convergence rate of a Monte Carlo Markov chain scales with sample size, $n$, and/or number of covariates, $p$. This article provides a thorough convergence complexity analysis of Albert and Chib’s [ J. Amer. Statist. Assoc. 88 (1993) 669–679] data augmentation algorithm for the Bayesian probit regression model. The main tools used in this analysis are drift and minorization conditions. The usual pitfalls associated with this type of analysis are avoided by utilizing centered drift functions, which are minimized in high posterior probability regions, and by using a new technique to suppress high-dimensionality in the construction of minorization conditions. The main result is that the geometric convergence rate of the underlying Markov chain is bounded below 1 both as $n ightarrowinfty$ (with $p$ fixed), and as $p ightarrowinfty$ (with $n$ fixed). Furthermore, the first computable bounds on the total variation distance to stationarity are byproducts of the asymptotic analysis. Full Article
of Convergence rates of least squares regression estimators with heavy-tailed errors By projecteuclid.org Published On :: Tue, 21 May 2019 04:00 EDT Qiyang Han, Jon A. Wellner. Source: The Annals of Statistics, Volume 47, Number 4, 2286--2319.Abstract: We study the performance of the least squares estimator (LSE) in a general nonparametric regression model, when the errors are independent of the covariates but may only have a $p$th moment ($pgeq1$). In such a heavy-tailed regression setting, we show that if the model satisfies a standard “entropy condition” with exponent $alphain(0,2)$, then the $L_{2}$ loss of the LSE converges at a rate [mathcal{O}_{mathbf{P}}igl(n^{-frac{1}{2+alpha}}vee n^{-frac{1}{2}+frac{1}{2p}}igr).] Such a rate cannot be improved under the entropy condition alone. This rate quantifies both some positive and negative aspects of the LSE in a heavy-tailed regression setting. On the positive side, as long as the errors have $pgeq1+2/alpha$ moments, the $L_{2}$ loss of the LSE converges at the same rate as if the errors are Gaussian. On the negative side, if $p<1+2/alpha$, there are (many) hard models at any entropy level $alpha$ for which the $L_{2}$ loss of the LSE converges at a strictly slower rate than other robust estimators. The validity of the above rate relies crucially on the independence of the covariates and the errors. In fact, the $L_{2}$ loss of the LSE can converge arbitrarily slowly when the independence fails. The key technical ingredient is a new multiplier inequality that gives sharp bounds for the “multiplier empirical process” associated with the LSE. We further give an application to the sparse linear regression model with heavy-tailed covariates and errors to demonstrate the scope of this new inequality. Full Article
of On deep learning as a remedy for the curse of dimensionality in nonparametric regression By projecteuclid.org Published On :: Tue, 21 May 2019 04:00 EDT Benedikt Bauer, Michael Kohler. Source: The Annals of Statistics, Volume 47, Number 4, 2261--2285.Abstract: Assuming that a smoothness condition and a suitable restriction on the structure of the regression function hold, it is shown that least squares estimates based on multilayer feedforward neural networks are able to circumvent the curse of dimensionality in nonparametric regression. The proof is based on new approximation results concerning multilayer feedforward neural networks with bounded weights and a bounded number of hidden neurons. The estimates are compared with various other approaches by using simulated data. Full Article
of Negative association, ordering and convergence of resampling methods By projecteuclid.org Published On :: Tue, 21 May 2019 04:00 EDT Mathieu Gerber, Nicolas Chopin, Nick Whiteley. Source: The Annals of Statistics, Volume 47, Number 4, 2236--2260.Abstract: We study convergence and convergence rates for resampling schemes. Our first main result is a general consistency theorem based on the notion of negative association, which is applied to establish the almost sure weak convergence of measures output from Kitagawa’s [ J. Comput. Graph. Statist. 5 (1996) 1–25] stratified resampling method. Carpenter, Ckiffird and Fearnhead’s [ IEE Proc. Radar Sonar Navig. 146 (1999) 2–7] systematic resampling method is similar in structure but can fail to converge depending on the order of the input samples. We introduce a new resampling algorithm based on a stochastic rounding technique of [In 42nd IEEE Symposium on Foundations of Computer Science ( Las Vegas , NV , 2001) (2001) 588–597 IEEE Computer Soc.], which shares some attractive properties of systematic resampling, but which exhibits negative association and, therefore, converges irrespective of the order of the input samples. We confirm a conjecture made by [ J. Comput. Graph. Statist. 5 (1996) 1–25] that ordering input samples by their states in $mathbb{R}$ yields a faster rate of convergence; we establish that when particles are ordered using the Hilbert curve in $mathbb{R}^{d}$, the variance of the resampling error is ${scriptstylemathcal{O}}(N^{-(1+1/d)})$ under mild conditions, where $N$ is the number of particles. We use these results to establish asymptotic properties of particle algorithms based on resampling schemes that differ from multinomial resampling. Full Article
of Correction: Sensitivity analysis for an unobserved moderator in RCT-to-target-population generalization of treatment effects By projecteuclid.org Published On :: Wed, 15 Apr 2020 22:05 EDT Trang Quynh Nguyen, Elizabeth A. Stuart. Source: The Annals of Applied Statistics, Volume 14, Number 1, 518--520. Full Article