Substituted phenylcarbamoyl alkylamino arenes; substituted phenylthiocarbamyl alkylamino arenes; substituted phenylcarbamoyl alkylamino heteroarenes; substituted phenylthiocarbamyl alkylamino heteroarenes; N-substituted aryl, N'-substituted aryl urea compounds; N-substituted aryl, N'-substituted heteroaryl urea compounds; N-substituted aryl, N'-substituted aryl thiourea compounds and N-substituted aryl, N'-substituted heteroaryl thiourea compounds are provided and may find use as androgen receptor modulators. The compounds may find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.

Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula: wherein, R1 is ONO2, CH2ONO2, CnH2n+1OH, CnH2n+1OH, or CH2CH2CH3, or H;R2 is ONO2, CH2ONO2, Cn'H2n'+1OH, Cn'H2n'+1OH, CH2CH2CH3 or H; andR3 is ONO2, CH2ONO2, Cn'″H2n″+1OH, Cn″H2n″+1OH, CH2CH2CH3 or H; wherein n is an integer from 0 to 9, n' is an integer from 0 to 9, and n″ is an integer from 0 to 9, and n+n'+n″≦9, and wherein at least one of R1, R2, and R3 is an ester nitrate selected from the group consisting of ONO2, CH2ONO2, and combinations thereof.

The present invention relates to processes for preparing 3-methylsulfonylpropionitrile. The processes provide a good yield and a good purity of the final product and provide a controllable reaction. The present invention also relates to a crystalline form of 3-methylsulfonylpropionitrile having X-ray diffraction peaks at 13.9±0.1, 19.2±0.1, 20.0±0.1, 22.5±0.1, 23.2±0.1, 25.7±0.1, 28.1±0.1, 29.9±0.1, and 30.6±0.1 degrees 2θ, and wherein the most intense peak is the peak at 13.9±0.1 degrees 2θ.

There is provided a method for producing an aqueous acrylamide solution by reacting a composition including acrylonitrile with water to produce acrylamide, in which the composition including acrylonitrile includes 3 to 15 mg of propionitrile per 1 kg of the total weight of the composition including acrylonitrile. According to the present invention, a production method with which it is possible to suppress acrylamide polymerization without lowering quality and thereby obtain a stable aqueous acrylamide solution can be provided.

An improved multi-reaction zone process provides for improved nitrile product quality and yield. In a first reaction zone, 1,3-butadiene is reacted with hydrogen cyanide in the presence of a catalyst to produce pentenenitriles comprising 3-pentenenitrile and 2-methyl-3-butenenitrile. In a second reaction zone, 2-methyl-3-butenenitrile, recovered from the first reaction zone, is isomerized to 3-pentenenitrile. In an optional third reaction zone, 3-pentenenitrile recovered from the first and second reaction zones is reacted with hydrogen cyanide in the presence of a catalyst and a Lewis acid to produce adiponitrile. A portion of the first catalyst is purified and recycled. Zero valent nickel is added to the purified first catalyst before it is recycled.

Adiponitrile is made by reacting 3-pentenenitrile with hydrogen cyanide. The 3-pentenenitrile is made by reacting 1,3-butadiene with hydrogen cyanide and by isomerizing 2-methyl-3-butenenitrile. The reaction of 1,3-butadiene with hydrogen cyanide to produce 3-pentenenitrile also produces small amounts of dinitrile compounds, including adiponitrile (ADN) and methylglutaronitrile (MGN). Methylglutaronitrile is removed to provide an adiponitrile-enriched stream, which is used in a catalyst purification step.

The present invention relates to a process for hydrocyanating 3-pentenenitrile. The process can include feeding 3-pentenenitrile and HCN to a hydrocyanation reaction zone that includes a Lewis acid promoter, nickel, and a phosphorus-containing ligand. In various embodiments, the process can also include controlling water concentration within the hydrocyanation reaction zone sufficient to maintain a high activity of the ligand catalyst complex while recycling at least a portion of the ligand catalyst complex.

A method and apparatus for using an ad hoc peer-to-peer distributed message bus is provided. The method may include determining, by a local bus node, using a first power level communication protocol, that a remote bus node is available, obtaining, by the local bus node, connection information from the remote bus node using a second power level communication protocol, wherein the connection information comprises connection information for one or more remote endpoints associated with the remote bus node, and generating one or more local virtual endpoints, wherein each of the one or more local virtual endpoints corresponds to each of the one or more remote endpoints, and wherein the remote endpoint is described with reference to a well-known name, unique to the remote endpoint.

APIs discussed herein promote efficient and timely interoperability between hardware and software components within the media processing pipelines of media content players. A PhysMemDataStructure API facilitates a hardware component's direct access to information within a memory used by a software component, to enable the hardware component to use direct memory access techniques to obtain the contents of the memory, instead of using processor cycles to execute copy commands. The PhysMemDataStructure API exposes one or more fields of data structures associated with units of media content stored in a memory used by a software component, and the exposed fields store information about the physical properties of the memory locations of the units of media content. SyncHelper APIs are used for obtaining information from, and passing information to, hardware components, which information is used to adjust the hardware components' timing for preparing media samples of synchronously-presentable media content streams.

The system and method described herein may leverage passive and active vulnerability discovery to identify network addresses and open ports associated with connections that one or more passive scanners observed in a network and current connections that one or more active scanners enumerated in the network. The observed and enumerated current connections may be used to model trust relationships and identify exploitable weak points in the network, wherein the exploitable weak points may include hosts that have exploitable services, exploitable client software, and/or exploitable trust relationships. Furthermore, an attack that uses the modeled trust relationships to target the exploitable weak points on a selected host in the network may be simulated to enumerate remote network addresses that could compromise the network and determine an exploitation path that the enumerated remote network addresses could use to compromise the network.

An exemplary embodiment of the invention relates to a system and method for providing digital messaging services received from multiple sources over a communications network. The system includes a client system, including a display screen coupled to a communications link; a workstation including a web browser, a memory, and a processor, said workstation coupled to said communications link; a hosting system, including a graphics server, a content server, and a scheduling server, each in communication with each other via a communications link; and a workstation and data storage device coupled to the communications link; and a data storage device for storing data utilized by said hosting system. The client system requests and receives digital messaging services from said hosting system under a subscription agreement. Digital messaging services include advertisements procured from said client system, and one or more local content providers, national advertisers, local advertisers, corporate marketing groups, and advertising agencies. Interactive digital messaging services are also available through the present invention. A user accesses these services via a variety of input devices; such as a bar code scanner, a wireless telephone or personal digital assistant, a kiosk with touch screen design, microphone, or other similar input device.

An approach is disclosed that facilitates context delivery during communication sessions. The approach may be implemented in a computer infrastructure having computer executable code tangibly embodied on a computer readable storage medium having programming instructions operable to: render at least one service to a user device through a communication session; collect information of the communication session; and send the information of the communication session to a service provider when a call is setup between the user device and the service provider. The service provider renders the information of the communication session for viewing by the service provider.

A method, system and computer program product are disclosed for user initiated rule based restrictions on sending messages from a sender to a receiver in a communications network. The receiver establishes a set of rules for the sender that allows the sender a limited number of defined messages events with the receiver. The defined message events may be messages or message sessions. When the sender attempts to send a message to the receiver, it is determined whether a message session currently exists between the sender and the receiver. If a current session exists, the rules set by the receiver are used to determine if the message is allowed to be sent to the receiver. If a session does not currently exist, the rules are used to determine whether a new session is allowed. If a new message session is allowed, a new session is established, and the message is sent to the receiver during the new session.

Systems and methods reconfigure data transmitted on a network, the network using a communication protocol. The systems and methods include a processor that is operable to receive data from a second device on the network; a memory medium; and a data configurator operable to dynamically reconfigure the data from the second device, with the data from the second device being in the form of a network item defined by the second device. The data configurator is operable to pass the reconfigured data to the processor and/or the memory medium in the form of a device item that is native to the device. A data design tool generates a map configuration to define a unique relationship between the network item and the device item. The map configuration includes a network representation portion for data in the network item and a device representation portion for data in the data item.

A vehicle communication method comprises receiving a first wireless communication that is transmitted from a first remote device and managing a transmission of the first wireless communication over a vehicle network using a configurable message list. The receiving a first wireless communication is performed by a connectivity device coupled to a communication port of the vehicle network. The managing a transmission of the first wireless communication is performed by a message manager module of the connectivity device.

A method for depositing a wear-resistant decorative coating on a substrate, comprising a first stage of vacuum deposition on the surface of the substrate of a layer of at least one metal of the group titanium, zirconium, hafnium, vanadium, niobium, tantalum, chromium, molybedenum, tungsten and aluminium, to which is added at least one element of the group carbon, nitrogen, oxygen, boron, silicon, fluorine, chlorine, sulfur and phosphorus; a second stage including activation of the first layer by ionic bombardment under vacuum conditions and simultaneous deposition of a second fine layer of a metal or metal alloy; and a third stage involving galvanic deposition of a third layer of a decorative metal coating over the second layer.

The rotating metal rim (19) is equipped with a toothed ring made of synthetic material (23) catch-fastened to the rotatating rim and catch-mounted on the frame (1) or by means of a band. The toothing of the ring (23) cooperates with at least one pawl (9) mounted in a recess of the frame and held in place on the one hand by a foot (11) and on the other hand by the rotating rim itself. The mounting of the unit and the after-sales service are facilitated.

A clock security device to be hung on a wall of a facility such as, for example, a store. The clock face has a convex mirrored surface which provides reflected panoramic view of the facility. The clock security device also includes a mounting bracket which provides for the mounting of the clock security device on the wall with the concave mirrored surface at different positions from parallel to the wall to tilted downwardly at different selected angles to the wall.

A cap (2) is made of sintered hard metal and has on the inside a cylindrical surface (20) and a frusto-conical surface (21) that are true ground. The cap's cylindrical surface (20) is fitted with radial play around an outer cylindrical surface (9) of an underlying middle (1) and the cap's frusto-conical surface (21) has the same inclination as a subjacent frusto-conical surface (14) on the outside of the middle. The cap (2) and the middle (1) are secured to one another by a ring of deformable material sandwiched between their cylindrical surfaces (9, 20). On the outside the cap (2) is formed over its thicker main portion (18) with a trued and polished surface (22) having the same inclination as its inside frusto-conical surface (21) such as to provide the thicker portion (18) with a parallelogrammatic cross-section.

When a speech sound of at least a predetermined sound pressure is externally input while a time measurement is not being performed, a time measuring circuit starts a time measurement responsive to a signal from a speech detector. When another speech sound of at least a predetermined sound pressure is externally input while a time measurement is being performed by the time measuring circuit, a measurement time measured by the time measuring circuit at this moment is stored in a time information memory. After a predetermined time has elapsed, if a speech recognition circuit recognizes that the externally input speech sound is a "stop" command, the time measurement operation performed by the time measuring circuit is stopped, and the time information stored in the time information memory is read out and displayed as measurement time information on a display unit.

An analog type electronic watch having a step motor to drive hands has a movement indicator other than hands. The movement indicator has a magnet member and is driven with the magnetic influence of a rotor magnet of the step motor. The magnet member is arranged within a window provided in a dial plate of the watch within the range of the magnetic force of the rotor. The movement indicator is supported so as to be synchronously moved with the rotation of the rotor under the magnetic influence.

The disclosed device enables the recording of television broadcasts which are preprogrammed in a memory. The presence of data lines of the television signal in combination with the presence of a color television signal is checked. When the data lines stop, the video recorder is switched on in real time by a clock time signal.

A method is described for detecting the time messages in the faulty signal of a time-signal transmitter comprising the steps below. Probabilities are assigned to the received information/bits as they are received and whose sign specifies the value of the bit and whose numerical value indicates the certainty of reception. Except for the bits designating the minute information, the probabilities of successive time messages are totaled with time correctness in a one-dimensional memory field. From the totaled probabilities, a reduced time message is reconstructed that initially contains no information on the minutes. If the reconstructed time message does not change over two successive time intervals, and if preset minimum values for the number of probabilities are exceeded for all bits, then the reduced time message is recognized as being correct. The minutes are determined separately and added to the time message recognized as being correct.

A process is disclosed for producing tertiary alcohols by radical addition of secondary alcohols to alkenes. The reaction is carried out as a continuous process in the presence of an organic peroxide as a radical initiator and during a mean contact time of the reaction mixture of up to a maximum of 1 hour.

A radio paging selective receiver determines that a received message is unread based on the time difference between the message reception time and the current time being larger that some predetermined value of time, and the paging selective receiver provides an indication of the unread message by displaying the reception time of the unread message in a second fashion which is visibly different from a first fashion normally used to display the current time.

A system includes a system time counter associated with a micro controller and a secure clock module having a real time clock and an elapsed time counter. The system synchronizes operation between the secure clock module and the system time counter. The synchronized time entered into the system time counter is utilized in the operation of the system. The real time clock time can be caused to be entered into the elapsed time counter at certain point in the operation of the system. The relationship of the time provide enhanced systems security.

An electronic data system for use with sporting impliments for providing a user with an electronic device integrated into sport gloves to perform various functions unique to that particular sport. The electronic data system for use with sporting impliments includes a glove member designed for substantially enveloping a hand of a user. The glove member has a notch portion in a back side of the glove member. The notch portion is for facilitating insertion and removal of the user's hand from the glove member. The glove member has a tab portion positioned adjacent to a first side of the notch portion. A data assembly has a housing. The housing is operationally coupled to the glove member. The data assembly has a display for presenting a visual representation of information to the user.

A method and device for synchronizing the time between at least two integrated circuits (201, 202), which receive the same pulse signal. In the integrated circuits (201, 202) a counter (204, 206) is used to count the number of pulses in the received pulse signal to synchronize the common time between said integrated circuits.

A wristwatch, which comprises an atomic oscillator comprising a system for detecting the beat frequencies obtained by the Raman effect.

A Redundant Array of Independent Disks (RAID) controller receives new data that is to be written, wherein the new data is indicated in blocks of a first block size. The RAID controller reads old data, and old parity that corresponds to the old data, stored in blocks of a second block size that is larger in size than the first block size. The RAID controller computes new parity based on the new data, the old data, and the old parity. The RAID controller writes the new data and the new parity aligned to the blocks of the second block size, wherein portions of the old data that are not overwritten by the RAID controller are also written to the blocks of the second block size.

A Redundant Array of Independent Disks (RAID) controller receives new data that is to be written, wherein the new data is indicated in blocks of a first block size. The RAID controller reads old data, and old parity that corresponds to the old data, stored in blocks of a second block size that is larger in size than the first block size. The RAID controller computes new parity based on the new data, the old data, and the old parity. The RAID controller writes the new data and the new parity aligned to the blocks of the second block size, wherein portions of the old data that are not overwritten by the RAID controller are also written to the blocks of the second block size.

Various systems and methods are described for configuring a data storage system. In one embodiment, a plurality of actual capacities of a plurality of storage devices of the data storage system are identified and divided into a plurality of capacity slices. The plurality of capacity slices are combined into a plurality of chunks of capacity slices, each having a combination of characteristics of the underlying physical storage devices. The chunks of capacity slices are then mapped to a plurality of logical storage devices. A group of the plurality of logical storage devices is then organized into a redundant array of logical storage devices.

A memory storage apparatus, a memory controller and method for transmitting and identifying data streams are provided. The memory controller passes at least a portion of a data stream received from a host system to a smart card chip of the memory storage apparatus. Then, the host system accurately receives a response message from the smart card chip by executing a plurality of read commands. The memory controller is capable of adding a first verification code to a response data stream sent to the host system, and is capable of adding a write token to each of data segments of the response data stream. The host system confirms the accuracy of the response data stream by verifying the first verification code or by verifying the write token of each of the data segments.

For a plurality of input/output (I/O) operations waiting to assemble complete data tracks from data segments, a process, separate from a process responsible for the data assembly into the complete data tracks, is initiated for waking a predetermined number of the waiting I/O operations.

Techniques for handling version information using a copy engine. In one embodiment, an apparatus comprises a copy engine configured to perform one or more operations associated with a block memory operation in response to a command. Examples of block memory operations may include copy, clear, move, and/or compress operations. In one embodiment, the copy engine is configured to handle version information associated with the block memory operation based on the command. The one or more operations may include operating on data in a cache and/or modifying entries in a memory. In one embodiment, the copy engine is configured to compare version information in the command with stored version information. The copy engine may overwrite or preserve version information based on the command. The copy engine may be a coprocessing element. The copy engine may be configured to maintain coherency with other copy engines and/or processing elements.

In a computer system that includes multiple nodes and multiple logical partitions, a dynamic partition manager computes current memory affinity and potential memory affinity to help determine whether a reallocation of resources between nodes may improve memory affinity for a logical partition or for the computer system. If so, the reallocation of resources is performed so memory affinity for the logical partition or computer system is improved. Memory affinity is computed relative to the physical layout of the resources according to a hardware domain hierarchy that includes a plurality of primary domains and a plurality of secondary domains.

A memory system includes a volatile first storing unit, a nonvolatile second storing unit, and a controller. The controller performs data transfer, stores management information including a storage position of the data stored in the second storing unit into the first storing unit, and performs data management while updating the management information. The second storing unit has a management information storage area for storing management information storage information including management information in a latest state and a storage position of the management information. The storage position information is read by the controller during a startup operation of the memory system and includes a second pointer indicating a storage position of management information in a latest state in the management information storage area and a first pointer indicating a storage position of the second pointer. The first pointer is stored in a fixed area in the second storing unit and the second pointer is stored in an area excluding the fixed area in the second storing unit.

Methods and apparatuses for implementing a system cache with quota-based control. Quotas may be assigned on a group ID basis to each group ID that is assigned to use the system cache. The quota does not reserve space in the system cache, but rather the quota may be used within any way within the system cache. The quota may prevent a given group ID from consuming more than a desired amount of the system cache. Once a group ID's quota has been reached, no additional allocation will be permitted for that group ID. The total amount of allocated quota for all group IDs can exceed the size of system cache, such that the system cache can be oversubscribed. The sticky state can be used to prioritize data retention within the system cache when oversubscription is being used.

A mechanism is provided in a storage device for performing a write operation. The mechanism configures a write buffer memory with a plurality of write buffer portions. Each write buffer portion is dedicated to a predetermined block size category within a plurality of block size categories. For each write operation from an initiator, the mechanism determines a block size category of the write operation. The mechanism performs each write operation by writing to a write buffer portion within the plurality of write buffer portions corresponding to the block size category of the write operation.

A dispersed storage (DS) unit for use within a dispersed storage network is capable of self-configuring using registry information provided to the DS unit. The registry information includes a slice name assignment indicating a range of slice names corresponding to a plurality of potential data slices of potential data objects to be stored in the DS unit. Based on the registry information, the DS unit allocates a portion of physical memory to store the potential data slices.

A partition manager relocates a logical partition from a primary shared processor pool to a secondary shared processor pool in response to a predetermined condition, such as a hardware failure. The relocated logical partition is allocated a smaller quantity of processing units from the secondary pool than it was allocated from the primary pool. A quantity of processing units reserved for a second logical partition is identified in the secondary shared processor pool, and a portion of those reserved processing units are allocated to the relocated logical partition. The reserved processing units may be redistributed among multiple relocated logical partitions.

The invention pertains to a memory management unit for a microprocessor system, the memory management unit being connected or connectable to at least one processor core of the microprocessor system and being connected or connectable to a physical memory of the microprocessor system. The memory management unit is adapted to selectively operate in a hypervisor mode or in a supervisor mode, the hypervisor mode and the supervisor mode having different privilege levels of access to hardware The memory management unit comprises a first register table indicating physical address information for mapping at least one logical physical address and at least one actual physical address onto each other; a second register table indicating an allowed address range of physical addresses accessible to a process running in or under supervisor mode; wherein the memory management unit is adapted to prevent write access to the second register table by a process not in hypervisor mode. The memory management unit is further adapted to allow write access to the first register table of a process running in or under supervisor mode to reconfigure the physical address information indicated in the first register table with memory mapping information relating to at least one physical address, if the at least one physical address is in the allowed address range, and to prevent write access to the first register table of the process running in or under supervisor mode if the at least one physical address is not in the allowed address range. The invention also pertains to a microprocessor system and a method for managing memory.

A dynamically expandable and contractible fault-tolerant storage system employs a virtual hot spare that is created from unused storage capacity across a plurality of storage devices. This unused storage capacity is available if and when a storage device fails for storage of data recovered from the remaining storage device(s). On an ongoing basis, the storage system may determine the amount of unused storage capacity that would be required for the virtual hot spare (e.g., based on the number of storage devices, the capacities of the various storage devices, the amount of data stored, and the manner in which the data is stored) and generate a signal if additional storage capacity is needed for a virtual hot spare.

A data processing entity that includes a mass memory with a plurality of memory locations for storing memory blocks. Each of a plurality of software images includes a plurality of memory blocks with corresponding image addresses within the software image. The memory blocks of software images stored in boot locations of a current software image are relocated. The boot blocks of the current software image are stored into the corresponding boot locations. The data processing entity is booted from the boot blocks of the current software image in the corresponding boot locations, thereby loading the access function. Each request to access a selected memory block of the current software image is served by the access function, with the access function accessing the selected memory block in the associated memory location provided by the control structure.

The present application relates to novel substituted 1-benzylcycloalkylcarboxylic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

The present application relates to novel 3-phenylpropionic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.

According to one embodiment, an actinic-ray- or radiation-sensitive resin composition includes any of the compounds (A) of general formula (I) below that when exposed to actinic rays or radiation, generates an acid and a resin (B) whose rate of dissolution into an alkali developer is increased by the action of an acid. (The characters used in general formula (I) have the meanings mentioned in the description.)

A radiation-sensitive composition includes a compound represented by a formula (1), and a polymer having a structural unit that includes an acid-labile group. In the formula (1), R1 represents a group having a polar group; n is an integer of 1 to 4, wherein, in a case where R1 is present in a plurality of number, the plurality of R1s are identical or different, and optionally at least two R1s taken together represent a cyclic structure; A represents an alicyclic hydrocarbon group having a valency of (n+1); and M+ represents a monovalent onium cation.

The invention discloses a deep-ultraviolet chemically-amplified positive photoresist. The deep-ultraviolet chemically-amplified positive photoresist according to one embodiment of the invention includes a cyclopentenyl pimaric acid, a divinyl ether, a photoacid generator and an organic solvent. The deep-ultraviolet chemically-amplified positive photoresist according to the invention has a good sensitivity and a good transparency.

The invention features methods and compositions for the synthesis of multimerizing agents. An exemplary method for producing AP20187 may comprise: (a) coupling 2-N,Ndimethylaminomethyl-1,3-diaminopropane with AP20792 to produce the dimeric alcohol, AP20793; and (b) coupling the AP20793 so produced with API7362 to yield AP20187. In particular embodiments, the method further includes the step of producing API7362 by coupling API7360 with methyl-L-pipecolic acid, or a salt thereof.