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Facet-engineered CeO2 with Cu single atom drives photocatalytic selective oxidation of 5-hydroxymethylfurfural

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02230K, Research Article
Yifei Li, Senyao Meng, Ping Wang, Miao He, Jiasai Yao, Cheng Yang, Fangzhou Mo, Jiang Li, Zhenxing Li
The crystal facet of CeO2 is crucial in governing the catalytic performance. However, studies on the relationship between the photocatalytic oxidation performance of CeO2 and its crystal facets are scarce....
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Exchange of equatorial ligands in protein-bound paddlewheel Ru25+ complexes: new insights from X-ray crystallography and quantum chemistry

Inorg. Chem. Front., 2024, 11,7803-7811
DOI: 10.1039/D4QI01846J, Research Article
Open Access
Aarón Terán, Francesca Fasulo, Giarita Ferraro, Ana Edilia Sánchez-Peláez, Santiago Herrero, Michele Pavone, Ana Belén Muñoz-García, Antonello Merlino
The reactivity of [Ru2Cl(D-p-CNPhF)(O2CCH3)3]n (D-p-CNPhF = N,N'-bis(4-cyanophenyl)formamidinate) with the model protein RNase A has been investigated by X-ray crystallography and Quantum Chemistry.
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A tetranuclear-cluster-based MOF with a low-polarity pore environment for efficient C2H6/C2H4 separation

Inorg. Chem. Front., 2024, 11,7947-7954
DOI: 10.1039/D4QI01685H, Research Article
Meng Feng, Jiantang Li, Xirong Wang, Jingyu Wang, Dongmei Wang, Banglin Chen
Benefitting from reticular chemistry, the newly developed MOF material ZJNU-400 establishes a low-polarity environment that enables reversed ethane adsorption and facilitates the efficient separation of C2H6/C2H4.
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Design of DyIII single-molecule magnets with molecularly installed luminescent thermometers based on bridging [PtII(CN)2(C^N)]− complexes

Inorg. Chem. Front., 2024, 11,7966-7978
DOI: 10.1039/D4QI02373K, Research Article
Pawel J. Bonarek, Mikolaj Zychowicz, Jan Rzepiela, Michal Liberka, Sebastian Baś, Jakub J. Zakrzewski, Szymon Chorazy
Dysprosium(III) single-molecule magnets are bridged within a coordination polymer by Pt(II)-cyanido metalloligands serving as their temperature sensors.
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Copper-doped Bi2MoO6 with concurrent oxygen vacancies for enhanced CO2 photoreduction

Inorg. Chem. Front., 2024, 11,8003-8015
DOI: 10.1039/D4QI02005G, Research Article
Jiawei Liu, Xin Liu, Chunhui Dai, Chao Zeng, Sajjad Ali, Mohamed Bououdina, Yushuai Jia
Bi2MoO6 catalysts doped by monovalence Cu with self-adapting O vacancies (Ov) are prepared. The optimal Bi2MoO6–10% Cu exhibits an outstanding CO evolution rate of 11.40 μmol g−1 h−1, about 6 times higher than that of Bi2MoO6 (1.94 μmol g−1 h−1).
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In situ growth of δ-MnO2/C fibers as a binder-free and free-standing cathode for advanced aqueous Zn-ion batteries

Inorg. Chem. Front., 2024, 11,8016-8024
DOI: 10.1039/D4QI01661K, Research Article
Yan Li, Fei Zhang, Miaomiao Wu, Yong Guo, Yuanyuan Liang, Reyihanguli Ababaikeri, Luyang Wang, Qiao Liu, Xingchao Wang
δ-MnO2 anchored in N-doped carbon fibers, derived from coal, was prepared using an electrospinning method, demonstrating enhanced performance in AZIBs.
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A high-entropy FeCoMnCuNi diselenide self-standing electrode with outstanding water-electrolysis performance in alkaline medium

Inorg. Chem. Front., 2024, 11,7936-7946
DOI: 10.1039/D4QI01835D, Research Article
Xinxin Guo, Mengmeng Zhou, Ziwu Liu, Shiheng Mu, Kaijia Wang, Huanqiang Shi, Fang Wang, Shijian Lu, Zhonghai Ni, Guiqing Liu
A self-standing high-entropy FeCoMnCuNiSe2 electrode exhibited superior HER activity and OWS performance due to high entropy, lattice distortion and tip-enhancement effects.
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Equivalent cation-tuning to realize a new Ce(IV) fluoride with excellent comprehensive nonlinear optical performances

Inorg. Chem. Front., 2024, 11,8130-8138
DOI: 10.1039/D4QI02088J, Research Article
Bei-Bei Zhang, Wen-Ye Gao, Wei Xu, Liang Ma, Wenlong Liu, Ru-Ling Tang, Sheng-Ping Guo
The acentric Ce(IV) fluoride NH4Ce3F13 is systematically studied, exhibiting the strong SHG effect (1.2 × KDP) and high LIDTs (39 × AGS). It also possesses the largest band gap among NLO materials containing Ce(IV).
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Mesoscopic spiral nanoplates formed by porphyrin-spaced coordination frameworks for enhanced H2O2 photosynthesis

Inorg. Chem. Front., 2024, 11,8037-8046
DOI: 10.1039/D4QI01580K, Research Article
Liang He, Er-Xia Chen, Ju-Qiang Xiang, Yu-Jun Guo, Jian Zhang, Qipu Lin
Two-dimensional chiral bismuth–porphyrin metal–organic frameworks featuring mesoscopic square spiral terrace morphology significantly enhance H2O2 photosynthesis.
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Towards ultra-sensitive multimodal luminescent thermometers enabled by high crystal field strength of Lu2CaMg2Ge3O12:Yb3+,Nd3+,Er3+ phosphors

Inorg. Chem. Front., 2024, 11,7955-7965
DOI: 10.1039/D4QI01767F, Research Article
Zhijiao Zhao, Mengmeng Dai, Kejie Li, Guiying Liang, Yanling Wei, Zuoling Fu
An effective full-spectrum thermometer covering from the visible to NIR-II band was designed based on garnet Lu2CaMg2Ge3O12:Yb3+,Er3+/Nd3+ phosphors; meanwhile, Er3+ (4I13/2) split into four Stark sublevels due to high crystal field strength.
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Research progress in optical materials with cationic organic planar π-conjugated groups containing CN bonds

Inorg. Chem. Front., 2024, 11,7756-7774
DOI: 10.1039/D4QI02232G, Review Article
Hangwei Jia, Xueling Hou, Shilie Pan
The calculated polarizability anisotropy, hyperpolarizability and HOMO–LUMO gap of optically active groups.
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A long-range synergistic effect between Ptn clusters and Zn1 single atoms for efficient selective hydrogenations

Inorg. Chem. Front., 2024, 11,7822-7830
DOI: 10.1039/D4QI02027H, Research Article
Haisheng Wei, Jing Li, Xiaorui Yan, Tiantian Liu, Kairui Li, Dan Feng, Yujing Ren
Benefiting from the long-range synergistic effect between Ptn clusters and Zn1 single atoms, Ptn@Zn1-N–C displays superior catalytic performance in selective hydrogenations.
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Unusual solvent-regulated inversion of a metal stereocenter in an enantiopure Eu2L4 helicate: a new strategy for CPL inversion

Inorg. Chem. Front., 2024, 11,8093-8100
DOI: 10.1039/D4QI02276A, Research Article
Qing Ma, Sen Yin, Ziye Song, Ting Gao, Pengfei Yan, Yanyan Zhou, Hongfeng Li
The dinuclear helicate Eu2(LR)4 exhibits a solvent-regulated metal stereocenter Δ/Λ configurational inversion, independent of P/M helical conformational conversion. This reversal process is accompanied by an inversion of the CPL.
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Multicolor luminescence and afterglow from Cs2NaScCl6:Sb3+,Mn2+ crystals

Inorg. Chem. Front., 2024, 11,8123-8129
DOI: 10.1039/D4QI02019G, Research Article
Xiaojia Wang, Wei Zheng, Xiangzhou Zhang, Xiangxiang Chen, Yuhai Zhang
Cs2NaScCl6 crystals exhibit a pure blue emission originating from self-trapped excitons, which is significantly boosted by Mn2+/Sb3+ doping. The doped crystals shows not only a PL QY up to 62.4% but also a long afterglow after X-ray excitation.
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Shooting short-wavelength nonlinear optical materials with targeted balance performances in hydroxyborates through first-principles high-throughput screening

Inorg. Chem. Front., 2024, 11,7843-7852
DOI: 10.1039/D4QI02234C, Research Article
Chenxu Li, Abudukadi Tudi, Huanhuan Cheng, Qingyu Liu, Zhihua Yang, Shilie Pan
High-throughput screening of 222 hydroxyborates identified three as promising short-wavelength ultraviolet nonlinear optical. with phase-matching second harmonic generation capacity extending to the solar blind region (200–280 nm).
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Metal–organic framework micro-nano reactors as armour of Escherichia coli for hydrogen production in air

Inorg. Chem. Front., 2024, 11,8070-8077
DOI: 10.1039/D4QI02119C, Research Article
Yun Fan, Junyang Yan, Siyao Zhang, Ruifa Su, Baoli Zha, Weina Zhang
The MOF shell of an E. coli@ZIF-8 micro–nano reactor, used as armour for E. coli, not only protects the internal E. coli and improves its survival rate, but also delays the transport of oxygen to enable E. coli to produce hydrogen in air.
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Linker engineering in mixed-ligand metal–organic frameworks for simultaneously enhanced benzene adsorption and benzene/cyclohexane separation

Inorg. Chem. Front., 2024, 11,8101-8109
DOI: 10.1039/D4QI01796J, Research Article
Yong-Zheng Zhang, Xin-Dan Zhang, Yan-Kai Zhang, Fu-Tian Wang, Longlong Geng, Hui Hu, Zhen Li, Da-Shuai Zhang, Hongliang Huang, Xiuling Zhang
A novel mixed-ligand metal–organic framework, featuring naphthalene rings in its secondary linker, exhibits exceptional benzene adsorption and separation capacities.
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Modulating the birefringence of two-dimensional hybrid lead bromide perovskites using pyridine derivative cations

Inorg. Chem. Front., 2024, 11,7853-7859
DOI: 10.1039/D4QI01547A, Research Article
Li-Ling Zhang, Hua Huang, Qingran Ding, Hui-Ping Xiao, Qing-Yan Liu, Yu-Ling Wang
Crystal structures and optoelectronic performance of hybrid two-dimensional lead bromide halide perovskites are elaborately regulated by pyridyl cations, which achieve a significantly enhanced birefringence of 0.315 (550 nm) for crystal 2.
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Active molecular units in metal organic frameworks for artificial photosynthesis

Inorg. Chem. Front., 2024, 11,7682-7755
DOI: 10.1039/D4QI01363H, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Subrata Mandal, Sahar Yoosefi, Alexander K. Mengele, Sven Rau, Andrea Pannwitz
Metal–organic frameworks (MOFs) integrate photoactive and catalytic entities within a 3D structure. This review classifies photocatalytic MOFs by photosensitizer and catalyst localization and their roles in artificial photosynthesis.
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Correction: BaSc2(HPO3)4(H2O)2: a new nonlinear optical phosphite exhibiting a 3D {[Sc2(HPO3)4]2−}∞ anionic framework and phase-matchable SHG effect

Inorg. Chem. Front., 2024, 11,8146-8146
DOI: 10.1039/D4QI90072C, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ru-Ling Tang, Gang-Xiang Liu, Wen-Dong Yao, Li-Nan Zhang, Wenlong Liu, Sheng-Ping Guo
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Correction: Unexpected in crystallo reactivity of the potential drug bis(maltolato)oxidovanadium(IV) with lysozyme

Inorg. Chem. Front., 2024, 11,8147-8147
DOI: 10.1039/D4QI90073A, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Maddalena Paolillo, Giarita Ferraro, Irene Cipollone, Eugenio Garribba, Maria Monti, Antonello Merlino
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Optimizing the spin qubit performance of lanthanide-based metal–organic frameworks

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02324B, Research Article
Xiya Du, Lei Sun
Reducing the spin concentration, spin-orbit coupling strength, and ground spin state of lanthanide ions embedded in metal–organic frameworks improves their spin qubit performance.
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Reversible single-crystal to single-crystal photoreaction between a coordination comb and a ladder displays photo-switchable fluorescence

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02162B, Research Article
Ni-Ya Li, Xin-Yu Wang, Pei-Xuan Zhang, Ning-Ning Zou, Wen Qiu, Yu-Fei Xing, Yun-Jian Wang, Xiao-Yan Tang, Dong Liu
A unique coordination polymer can transform between comb-like and ladder-like bistable structures through reversible single-crystal-to-single-crystal photoreaction and exhibit photo-switchable fluorescence.
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Hierarchical FeCo LDH/NiSe heterostructure electrocatalysts with rich heterointerfaces for robust water splitting at industrial-level current density

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02426E, Research Article
Weiwei Han, Wenyi Wang, Jiahong Liao, Yi He, Xingwang Zhang, Chunlin Yu
Sustainable hydrogen production by electrocatalytic water splitting is a promising energy storage technology yet challenging due to the sluggish kinetics of the oxygen evolution reaction (OER). Rationally designed robust and...
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Ionic-liquid/metal-organic-framework composites: Synthesis and emerging sustainable applications

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02383H, Review Article
Maiyong Zhu
Ionic liquids (ILs) as emerging solvents have demonstrated a significant prospective in green chemistry, which can be used as green solvent, high efficiency catalyst, electrolyte, and so on. Metal–organic frameworks...
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Enhancing CO2 electroreduction with decamethylcucurbit[5]uril-alkaline earth metal modified Pd nanoparticles

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02135E, Research Article
Tao Shao, Xianmeng Song, Zongnan Wei, Shuaibing Yang, Siying Zhang, Rong Cao, Minna Cao
Pd NP modification with Me10CB[5]–M capsules boosted CO2RR by enhancing CO2 adsorption, tuning Pd's electronic structure, and optimizing *COOH/*CO binding.
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Ammonia and formate cosynthesis via nitrate electroreduction combined with methanol electrooxidation over nitrogen-doped carbon-encapsulated nickel iron phosphide

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02350A, Research Article
Zongyi Wang, Jiuli Chang, Zhiyong Gao
Nitrate–methanol co-electrolysis by the pairwise cathodic NO3RR and anodic MOR is a viable way to coproduce ammonia (NH3) and formate via gentle, sustainable and energy-saving “E-refining” and “E-reforming” means.
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Multifunctional separator modified with catalytic multishelled structural CoS2 enables a stable lithium–sulfur battery

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02340D, Research Article
Open Access
Ruyi Bi, Jilu Zhao, Mei Yang, Jiangyan Wang, Ranbo Yu, Dan Wang
A multifunctional separator modified with a multi-shelled CoS2 structure is developed to simultaneously inhibit the shuttle effect and effectively catalyze the redox reactions.
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Lithium extraction by metal–organic frameworks

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02228A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zongsu Han, Joshua Rushlow, Yihao Yang, Jiatong Huo, Wei Shi, Hong-Cai Zhou
Lithium extraction attracts great attention due to the rising demand for batteries, but faces challenges related to low natural abundance and environmental concerns. MOFs show promise in lithium extraction, benefitting from customizable structures.
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Pentagonal-bipyramidal Dysprosium(III) complexes with two apical phosphine oxide ligands and equatorial pentadentate N3O2 Schiff-base ligands: Breakdown of the apical magnetic axiality by strong equatorial crystal field†

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02262A, Research Article
Tamara A. Bazhenova, Vyacheslav Kopotkov, Denis V. Korchagin, Elena Yureva, Michael V. Zhidkov, Alexey I Dmitriev, Ilya Yakushev, N. N. Efimov, Konstantin Andreevich Babeshkin, Vladimir Sergeevich Mironov, Eduard B. Yagubskii
A series of three new seven-coordinate pentagonal-bipyramidal (PBPY-7) Dy(III) complexes [Dy(LCH3)(Cy3PO)2]ClO4∙CH3CN (1), [Dy(L2(t-Bu))(Ph3PO)2]ClO4∙0.63C2H5OH (2), [Dy(LOCH3)(Ph3PO)2]ClO4∙2H2O (3) including various chelating pentadentate ligands with a [N3O2]2− binding node in the equatorial plane,...
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Unraveling the Correlation between Biological Effects and Halogen Substituents in Cobalt bis(dicarbollide)

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02296C, Research Article
Katarzyna Zakret-Drozdowska, Bożena Szermer-Olearnik, Waldemar Goldeman, Michalina Gos, Dawid Drozdowski, Anna Gągor, Tomasz M. Goszczyński
Over the past decade, considerable scientific attention has been given to adapting cobalt bis(dicarbollides) as innovative agents with various biomedical applications. Although the studied compounds show great potential in this...
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Dynamic behavior of floating magnetic liquid marbles under steady and pulse-width-modulated magnetic fields

Lab Chip, 2024, 24,2005-2016
DOI: 10.1039/D3LC00578J, Paper
Hossein Dayyani, Alireza Mohseni, Mohamad Ali Bijarchi
The manipulation of biocompatible magnetic liquid marbles, formed by wrapping magnetic nanoparticles around water droplets, on the water surface under the steady and variable magnetic fields.
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Wearable intelligent sweat platform for SERS-AI diagnosis of gout

Lab Chip, 2024, 24,1996-2004
DOI: 10.1039/D3LC01094E, Paper
Zhaoxian Chen, Wei Wang, Hao Tian, Wenrou Yu, Yu Niu, Xueli Zheng, Shihong Liu, Li Wang, Yingzhou Huang
A wearable intelligent SERS platform enables the sensitive detection of UA (0.1 μM) in sweat for AI diagnosis of gout.
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Confining calcium oxalate crystal growth in a carbonated apatite-coated microfluidic channel to better understand the role of Randall's plaque in kidney stone formation

Lab Chip, 2024, 24,2017-2024
DOI: 10.1039/D3LC01050C, Paper
Samantha Bourg, Karol Rakotozandriny, Ivan T. Lucas, Emmanuel Letavernier, Christian Bonhomme, Florence Babonneau, Ali Abou-Hassan
The successful formation of a carbonated apatite coating inside a micrometer channel is described, which was used to investigate its role on the formation of calcium oxalate crystals in the context of kidney stones.
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AMF-SporeChip provides new insights into arbuscular mycorrhizal fungal asymbiotic hyphal growth dynamics at the cellular level

Lab Chip, 2024, 24,1930-1946
DOI: 10.1039/D3LC00859B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Felix Richter, Maryline Calonne-Salmon, Marcel G. A. van der Heijden, Stéphane Declerck, Claire E. Stanley
A new microfluidic platform – the AMF-SporeChip – enables immobilisation of arbuscular mycorrhizal fungal spores and confrontation of asymbiotic hyphae with physical obstacles, allowing the identification of various exploration strategies.
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Microfluidic impedance cytometry with flat-end cylindrical electrodes for accurate and fast analysis of marine microalgae

Lab Chip, 2024, 24,2058-2068
DOI: 10.1039/D3LC00942D, Paper
Xiaoming Chen, Mo Shen, Shun Liu, Chungang Wu, Liangliang Sun, Zhipeng Song, Jishun Shi, Yulong Yuan, Yong Zhao
We develop a novel microfluidic impedance cytometer for analysis of marine microalgae by inserting ground flat-end cylindrical electrodes into microchannels.
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Comparison between dynamic versus static models and real-time monitoring of neuronal dysfunction in an amyloid-β induced neuronal toxic model on a chip platform

Lab Chip, 2024, 24,1887-1902
DOI: 10.1039/D3LC00507K, Paper
Open Access
Chu-Chun Liang, Po-Yen Chen, Nien-Che Liu, I-Chi Lee
A 3D neural spheroid-based system with an interstitial level of flow for simulating the brain microenvironment toward a dynamic amyloid-β induced neuronal toxic model was established. A real-time impedance recording was used to monitor the neural network formation and disconnection.
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SeParate: multiway fluorescence-activated droplet sorting based on integration of serial and parallel triaging concepts

Lab Chip, 2024, 24,2107-2121
DOI: 10.1039/D3LC01075A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Wannes Verbist, Jolien Breukers, Sapna Sharma, Iene Rutten, Hans Gerstmans, Lotte Coelmont, Francesco Dal Dosso, Kai Dallmeier, Jeroen Lammertyn
A novel platform, called SeParate, enabling accurate multiplex droplet sorting by integrating serial and parallel sorting principles for three model systems with increasing complexity and intra-subpopulation variation in fluorescence intensities.
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Lab on skin: real-time metabolite monitoring with polyphenol film based subdermal wearable patches

Lab Chip, 2024, 24,2039-2048
DOI: 10.1039/D4LC00073K, Paper
Open Access
Georgeta Vulpe, Guoyi Liu, Sam Oakley, Guanghao Yang, Arjun Ajith Mohan, Mark Waldron, Sanjiv Sharma
Development of wearable sensing devices for minimally invasive and real time monitoring of physiological information in ambulatory conditions.
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Microphysiological pancreas-on-chip platform with integrated sensors to model endocrine function and metabolism

Lab Chip, 2024, 24,2080-2093
DOI: 10.1039/D3LC00838J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katharina Schlünder, Madalena Cipriano, Aline Zbinden, Stefanie Fuchs, Torsten Mayr, Katja Schenke-Layland, Peter Loskill
Pancreatic in vitro models are crucial for research on diseases such as diabetes mellitus. A novel thermoplastic organ-on-chip with integrated real-time read-outs models the complex microphysiological structure and function of the endocrine pancreas.
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Deciphering fibroblast-induced drug resistance in non-small cell lung carcinoma through patient-derived organoids in agarose microwells

Lab Chip, 2024, 24,2025-2038
DOI: 10.1039/D3LC01044A, Paper
Qiyue Luan, Ines Pulido, Angelique Isagirre, Julian Carretero, Jian Zhou, Takeshi Shimamura, Ian Papautsky
Agarose microwell platform for modeling lung carcinoma using patient-derived tissues to decipher cancer associated fibroblast-induced drug resistance.
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Recent developments and future perspectives of microfluidics and smart technologies in wearable devices

Lab Chip, 2024, 24,1833-1866
DOI: 10.1039/D4LC00089G, Critical Review
Sasikala Apoorva, Nam-Trung Nguyen, Kamalalayam Rajan Sreejith
Wearable devices are increasingly popular in health monitoring, diagnosis, and drug delivery. Advances allow real-time analysis of biofluids like sweat, tears, saliva, wound fluid, and urine.
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Direct laser writing-enabled 3D printing strategies for microfluidic applications

Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC00743J, Tutorial Review
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Olivia M. Young, Xin Xu, Sunandita Sarker, Ryan D. Sochol
This Tutorial Review highlights strategies for leveraging the micron-to-submicron-scale additive manufacturing technique, “direct laser writing”, to enable 3D microfluidic technologies.
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Screening for Urothelial Carcinoma Cells in Urine Based on Digital Holographic Flow Cytometry through Machine Learning and Deep Learning Method

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D3LC00854A, Paper
Lu Xin, Xi Xiao, Wen Xiao, Ran Peng, Hao Wang, Feng Pan
The incidence of urothelial carcinoma continue to rise annually, particularly among the elderly. Prompt diagnosis and treatment can significantly enhance patient survival and quality of life. Urine cytology remains a...
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Dielectrophoretic characterization and selection of non-spherical flagellate algae in parallel channels with right-angle bipolar electrodes

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00165F, Paper
Xiaoming Chen, Shun Liu, Mo Shen, Jishun Shi, Chungang Wu, Zhipeng Song, Yong Zhao
We develop a microfluidic device with closed right-angle bipolar electrodes to realize dielectrophoretic characterization and selection of non-spherical flagellate algae.
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Thermal segment microwell plate control for automated liquid handling setups

Lab Chip, 2024, 24,2224-2236
DOI: 10.1039/D3LC00714F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Simon Seidel, Katja F. Winkler, Anke Kurreck, Mariano Nicolas Cruz-Bournazou, Katharina Paulick, Sebastian Groß, Peter Neubauer
This publication introduces a thermal segment microwell plate control device, integrating smart sensor technology and standardized well-plate geometry for automated biolab setups. It is tested in a high-throughput enzymatic activity assay.
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Synthesis and photocatalytic property of Au–TiO2 nanocomposites with controlled morphologies in microfluidic chips

Lab Chip, 2024, 24,2253-2261
DOI: 10.1039/D3LC01053H, Paper
Ziran Ye, Ping Lu, Yiben Chen, Zhixian Xu, Haixia Huang, Mingjia Zhi, Zi Ang Chen, Bo Yan
We present an efficient approach for the consecutive synthesis of Au–TiO2 nanocomposites with controlled morphologies in a microfluidic chip.
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Deep learning-enabled detection of rare circulating tumor cell clusters in whole blood using label-free, flow cytometry

Lab Chip, 2024, 24,2237-2252
DOI: 10.1039/D3LC00694H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nilay Vora, Prashant Shekar, Taras Hanulia, Michael Esmail, Abani Patra, Irene Georgakoudi
We present a deep-learning enabled, label-free flow cytometry platform for identifying circulating tumor cell clusters in whole blood based on the endogenous scattering detected at three wavelengths. The method has potential for in vivo translation.
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Distance-based paper analytical device for multiplexed quantification of cytokine biomarkers using carbon dots integrated with molecularly imprinted polymer

Lab Chip, 2024, 24,2262-2271
DOI: 10.1039/D4LC00055B, Paper
Kawin Khachornsakkul, Ruben Del-Rio-Ruiz, Lita Chheang, Wenxin Zeng, Sameer Sonkusale
A carbon dots and dopamine-imprinted polymer was immobilized onto a distance-based paper channel for simultaneous detection of three cytokine biomarkers without requiring expensive reagents and instruments.
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Integrated biocompatible 3D printed isoporous membranes with 7 μm pores

Lab Chip, 2024, 24,2202-2207
DOI: 10.1039/D4LC00014E, Paper
Matthew S. Viglione, Aubrianna Saxton, Dawson Downs, Adam T. Woolley, Kenneth A. Christensen, Pam M. Van Ry, Gregory P. Nordin
A new 3D printing method allows for fabrication of porous membranes with 7 μm pores. A device mimicking an organ-on-a-chip design is fabricated and seeded with living cells, demonstrating potential for diverse biological and mechanical applications.
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