A liquid-crystal compound denoted by general formula (I) below wherein each of the groups is defined and Dye denotes an azo dye residue denoted by general formula (II) with X and n also being defined. The azo liquid-crystal compound is capable of orientation with a high degree of orientation order.

Described herein are pharmaceutical compositions and medicaments, and methods of using such pharmaceutical compositions and medicaments in the treatment of cancer.

A hypoxia contrast medium including nitroimidazole-amino acid chelate with a positively charged radioactive nuclide, a preparation method and use thereof. The contrast medium can be used in imaging cerebral thrombosis, tumors or other diseases such as ulceration, thrombosis, and so on.

The present invention relates to a process to dissolve plutonium or a plutonium alloy, by placing it in contact with an aqueous dissolution mixture, wherein said dissolution mixture comprises nitric acid, a carboxylic acid with complexing properties with respect to plutonium, and a compound comprising at least one —NH2 radical such as urea. The invention also relates to a process to convert plutonium or a plutonium alloy into plutonium oxide and to manufacture nuclear fuel from said oxide.The invention particularly applies to the dismantling of plutonium contained in nuclear weapons with a view to its use in civilian nuclear reactors, particularly in the form of MOX fuel.

One form of the invention is directed to an apparatus that comprises step-down circuitry to better match impedance between an input and an output that includes a number of stages each electrically coupled to another and each including a charge storage device. The circuitry further includes a number of switching devices operable in a first electrical connectivity state to connect the charge storage device of each of the stages in series to receive electrical charge from the input and in a second electrical connectivity state opposite the first state to connect the charge storage device of each of the stages in parallel to discharge electricity through the output. This circuitry can be used in connection with a radioisotopic conversion cell.

Compositions are provided that include nuclear fuel. Methods for treating nuclear fuel are provided which can include exposing the fuel to a carbonate-peroxide solution. Methods can also include exposing the fuel to an ammonium solution. Methods for acquiring molybdenum from a uranium comprising material are provided.

Compositions are provided that include nuclear fuel. Methods for treating nuclear fuel are provided which can include exposing the fuel to a carbonate-peroxide solution. Methods can also include exposing the fuel to an ammonium solution. Methods for acquiring molybdenum from a uranium comprising material are provided.

An apparatus for treating a radioactive nitrate waste liquid includes: a denitrification tank (12) that accommodates active sludge which adsorbs or takes in a radioactive substance in a nitrate waste liquid (11) containing nitrate and the radioactive substance and in which an anaerobic microorganism that reduces the nitrate to nitrogen gas grows; a reaeration tank (14) that aerates and mixes a denitrification-treated liquid (24) treated in the denitrification tank (12) with the active sludge in which the aerobic microorganism grows; and a sludge dissolution tank (81) that dissolves redundant sludge (26A, 26B) discharged from the denitrification tank (12) and the reaeration tank (14). Acetic peracid (80) is supplied to the sludge dissolution tank (81) to dissolve redundant sludge, a sludge lysate is supplied to the denitrification tank (12) as a carbon source (22), and acetic acid is supplied to the denitrification tank (12).

A reactor installation tool and method for installing a reactor unit in a reactor tube. A reactor installation tool including a movable assembly and a fixed assembly linked together such that the movable assembly can be adjusted relative to the fixed assembly. The movable assembly including a reactor sleeve attachment means for releasably securing a reactor sleeve loaded with a reactor unit to the tool. The fixed assembly including an expandable clamping unit for releasably securing the tool to a reactor tube. A reactor unit can be installed in the reactor tube by adjusting the movable assembly to extract the reactor unit from the reactor sleeve as the fixed assembly is rigidly secured to the reactor tube. The fixed assembly can be released from the reactor tube and the reactor installation tool can be removed from the reactor tube.

The invention relates to a polypeptide having a mutation at one or more position corresponding to T219 of SEQ ID NO: 55, wherein the polypeptide has at least 50% sequence identity with SEQ ID NO: 55, and wherein the polypeptide has permease activity.

Capture compounds and collections thereof and methods using the compounds for the analysis of biomolecules are provided. In particular, collections, compounds and methods are provided for analyzing complex protein mixtures, such as the proteome. The compounds are multifunctional reagents that provide for the separation and isolation of complex protein mixtures. Automated systems for performing the methods also are provided.

Acylated insulins wherein an acyl moiety is attached to the parent insulin and wherein the acyl moiety comprises repeating units of alkylene glycol containing amino acids and wherein there is only one lysine residue (K & Lys) in the parent insulin, having satisfactory properties when administered pulmonary.

Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.

This disclosure relates to temperature sensitive conjugates, compositions, and uses related thereto. In certain embodiments, the disclosure relates to conjugate polymers comprising a) a temperature sensitive polymer and b) an antibody. Typically the antibody has an epitope to a platelet receptor. The antibody may be a single-chain antibody wherein the platelet receptor is GPIIb/IIIa, such as an anti-GPIIb/IIIa antibody. In certain embodiments, the antibody binds specifically to the activated conformation of GPIIb/IIIa, i.e., an activation-specific GPIIb/IIIa antibody.

Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

The present invention relates to novel muteins derived from human lipocalin 2 (hNGAL) and related proteins that bind a given non-natural ligand with detectable affinity. The invention also related to corresponding nucleic acid molecules encoding such a mutein and to a method for their generation. The invention further relates to a method for producing such a mutein. Furthermore, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various uses of the mutein.

The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

A composition having proanthocyanidin compounds having an average degree of polymerization of at least about 6. A method of administering to an immunosuppressed patient or a patient diagnosed with sepsis or septic shock a composition having a proanthocyanidin. A method of administering to a patient diagnosed with a gram negative bacterial infection a composition having proanthocyanidin compounds having an average degree of polymerization of at least about 6.

Provided are a support for affinity chromatography which has excellent alkali resistance, and a method for isolating immunoglobulin. A support for affinity chromatography, containing an immobilized protein ligand represented by the following formula (1): R—R2 (1) wherein R represents a polypeptide consisting of 4 to 30 amino acid residues that contains an amino acid sequence represented by ATK or ASK; and R2 represents a polypeptide consisting of 50 to 500 amino acid residues containing an immunoglobulin-binding domain consisting of an amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 2, the partial sequence thereof, or an amino acid sequence having 70% or more identity to these sequences; with the proviso that a terminus at which R2 binds to R is C-terminus or N-terminus of the immunoglobulin-binding domain.

In an aspect, the invention relates to compositions and methods for permeabilizing membranes of cells. In an aspect, the invention relates to compositions and methods for killing cells. In an aspect, the invention relates to compositions and methods of permeabilizing the membranes of cancer cells or microbial cells.

Monitoring user activity on a mobile device is described. In one aspect, video content is received and played to a user of the mobile device. The monitoring activity detects an interruption of playback of the video content and determines an event associated with the interruption. The event is stored in the mobile device and communicated to a remote device.

An automatic content recognition (ACR)-enabled connected TV device may be associated with a paired device and the paired device may comprise a browser. The ACR-enabled connected TV device may be operable to enable, utilizing an ACR system, the browser to display, within a section of a browser window, interactive content related to certain content being presented by the ACR-enabled connected TV device. The ACR-enabled connected TV device may be operable to enable, utilizing the ACR system, a viewer to interact with the interactive content. The section of the browser window may be changed dynamically. The certain content may comprise an advertisement of a particular product and the interactive content may comprise a link to a website and/or other information related to the particular product. The certain content may comprise a program associated with a network and the interactive content may comprise information on polling questions related to the program.

A remote time shift buffer system with shadow tuning. The remote time shift buffer system includes a client in communication with a remote video recorder. The client tunes to a channel from a television signal source and sends the channel content to a television. When a channel change occurs at the client, the remote video recorder tunes to the same channel as the client and buffers the content. When a pause live television (PLTV) function is initiated, the remote video recorder generates an independent RTSB content stream using the buffered content. Once the RTSB content stream is available, the client switches inputs and displays the RTSB content stream from the remote video recorder. Manipulating the position within the RTSB content stream does not affect buffering of the live content. The remote time shift buffer system provides pause live television functionality with minimal loss of content.

In one embodiment, a broadcast transmitter includes: a viewer information memory configured to store viewer information regarding a viewer who signs up for a subscription; a generator configured to generate individual information regarding a conditional access of a content including a first expiration time indicating an expiration time of the individual information and a second expiration time set independently of the first expiration time for each the viewer who signs up for the subscription based on the viewer information; and a transmitter configured to transmit a broadcast signal including the generated individual information.

A method includes receiving, at a multimedia device, a data stream representing multimedia content, the data stream comprising first timing information for the multimedia content, and metadata representing interactive event information associated with the multimedia content, the metadata comprising second timing information for the interactive event information. During the playback of the multimedia content, a first user interactive event is identified that is associated with a first time point in the playback of the multimedia content based on the interactive event information, and the first user interactive event is performed concurrent with the first time point in the playback of the multimedia content.

The present invention provides techniques relating to rich media advertising. Techniques are provided in which an advertiser-provided image-based component of an advertisement creative is matched with an advertiser-provided audio component of the advertisement creative. A rich media advertisement may be served that includes the image-based component and a synchronously presented audio component. Presentation of the rich media advertisement on a user computer may not require downloading or utilization of a video player.

A digital television system is connected to a mobile computing and communication device through an ad hoc communication link. A program broadcasted by the television system includes a plurality frames delivered in a sequential manner. A user can freeze a frame by employing the mobile device. The frame can then be transmitted to the mobile device and be redisplayed on the mobile device. The redisplayed frame includes visible symbols pointing to displayed items associated with advertising messages. The frame can also be stored in a photograph folder for the user to view the frame and associated advertising messages in a later time.

A system and method in a television system for presenting information associated with a user-selected object in a television program is provided. An identity of a user-selected object in a television program being presented to a user is determined. Based at least in part on the identity of the user-selected object in the television program, information to present to the user is determined. The determined information is presented to the user on a television display.

An exemplary method includes a media service provider system 1) providing an end user of an integrated media service with access to a media program by way of a plurality of different media distribution models, 2) maintaining a catalog that includes comprehensive information about the media program, the comprehensive information being an aggregate of non-redundant information about the media program obtained from a plurality of independent source catalogs corresponding to the plurality of different media distribution models, and 3) providing, based on the comprehensive information included in the catalog, a media service user interface that supports discovery of the comprehensive information about the media program regardless of a user interface context from which a user request for information about the media program is received. Corresponding systems and methods are also described.

A display device such as a TV has both HDMI and IP network interfaces and uses the HDMI interface to exchange IP network parameters with an audio video application module (AVAM) upon HDMI connection. In this way, an IP-based peer-to-peer or client-server network connection can be automatically established to promote faster communication when sharing and executing applications between the devices than is typically available over the CEC link of HDMI.

A method for virtual channel management is provided. The method includes the following steps. In response to a command, a control unit of a network-based multimedia reproduction system determines whether the command is associated with virtual channel switching. When the command is associated with virtual channel switching, the control unit checks whether a channel value corresponding to the command exists in an application virtual channel table. When the channel value exists in the application virtual channel table, the control unit determines an application corresponding to the channel number from the application virtual channel table, and executes the application. According to a first operation parameter set corresponding to the application, the control unit sets the executed application to retrieve digital contents through a network unit of the network-based multimedia reproduction system.

An inflight entertainment (IFE) system preloads from head end equipment onto seat end video caches subsets of prerecorded video entertainment programs from a library of prerecorded video entertainment programs stored on the head end equipment. Preloading is done independent of play requests made by passengers using the IFE system. The selected subsets are selected using selection metrics such as program popularity, passenger demographics and/or passenger preferences. The same or a different subset may be selected for different passengers. As a result of the selective preloading of the seat end video caches, if the head end equipment or the distribution system becomes inoperable during the flight, the IFE system is able to continue to deliver a limited offering of popular, demographically indicated and/or passenger preferred video entertainment from the seat end video caches, without requiring a large multiplier in storage capacity or loading time.

An electronic device with one or more processors, memory and a display receives a first request to display a first video stream on the display. In response to receiving the first request, the electronic device displays the first video stream on the display. While displaying the first video stream on the display, the electronic device receives a second request to display a second video stream on the display. In response to receiving the second request, the electronic device displays at least a portion of the first video stream on the display concurrently with at least a portion of the second video stream, where the second video stream was received, at least in part, from a content source in response to a request from the electronic device to the content source for delivery of the second video stream from the content source.

Methods, devices, and computer program products for providing instant messaging in conjunction with an audiovisual, video, or audio program are provided. The methods include providing an audiovisual, video, or audio program to a user. Viewer/listener input is received requesting activation of a program-based instant messaging function. A viewer/listener identifier corresponding to the viewer/listener is associated with a program identifier that uniquely identifies the audiovisual, video, or audio program being provided to the user to thereby generate a program viewer/listener record. The program viewer/listener record is transmitted to an electronic database. A list of other users who are viewing or listening to the program in addition to the viewer/listener is acquired from the electronic database. The list of other users is transmitted to the viewer/listener.

Systems and methods for optimizing system performance of capacity and spectrum constrained, multiple-access communication systems by selectively discarding packets are provided. The systems and methods provided herein can drive changes in the communication system using control responses. One such control responses includes the optimal discard (also referred to herein as “intelligent discard”) of network packets under capacity constrained conditions. Some embodiments inspect a video stream to determine priorities for various elements of the video stream. The elements may be discarding using the priorities. In various embodiments, the elements include frames, slices, macroblocks, and data partitions.

A digital broadcast receiver on a mobile body includes: a tuner that receives a broadcast signal of a physical channel; a signal intensity detector that detects a signal intensity of the broadcast signal; a current position detector that detects a current position of the mobile body; a movement direction detector that detects a movement direction of the mobile body; a reception judging unit that controls the tuner to judge whether the physical channel can be received; an area information storage unit that stores receivable area information indicating a receivable area of the physical channel; and an area information updating unit that determines, when it is judged that the physical channel can be received, a position apart from the current position in the movement direction according to the signal intensity as a receivable position, and updates the receivable area information to extend the receivable area to the receivable position.

A method and apparatus for extracting advertisement keywords in association with situations of scenes of video include: establishing a knowledge database including a classification hierarchy for classifying situations of scenes of video and an advertisement keyword list, segmenting a video script corresponding to a received video in units of scenes, and determining a situation corresponding to each scene with reference to the knowledge database, and extracting an advertisement keyword corresponding to the situation of a scene of the received video with reference to the knowledge database.

Aspects of a method and system for data processing in a device with integrated set-top-box and femtocell functionality are provided. Data may be received via an integrated femtocell and set-top-box device and may be synchronously processed, utilizing a common clock, to perform one or more femtocell functions and/or set-top-box functions. The common clock may be derived from global navigation satellite system signals. The integrated femtocell and set-top-box device may convert the received data from a first to a second format. The converted data may be transmitted to a cellular enabled communication device via a cellular transmitter within said integrated femtocell and set-top-box device and/or to a multimedia device via a multimedia interface within said integrated femtocell and set-top-box device. The received data may comprise multimedia content. The integrated femtocell and set-top-box device may be operable to encode, decode, transcode, encrypt, decrypt, scramble, descramble, and present the received multimedia content.

A video-on-demand (VOD) content delivery system has a VOD Application Server which manages a database of templates ordered in a hierarchy for presentation of video content elements of different selected types categorized in hierarchical order. The templates include those for higher-order displays which have one or more links to lower-order displays of specific content. The VOD Application Server, in response to viewer request, displays a high-order templatized display, and in response to viewer selection of a link, displays the lower-order display of specific content. The hierarchical templatized displays enable viewers to navigate to an end subject of interest while having a unique visual experience of moving through a series of displays to the end subject of interest. For example, the higher-order display may be a product ad and the lower-order display may be an ad for a local retailer of the product. Similarly, a viewer can navigate from national product to local product ad, or classified ad category to specific classified ad, or bulletin board topic category to specific posting. In another embodiment, the VOD content delivery system is used to deliver consumer-generated classified ads on TV. A web-based Content Management System receives consumer-generated content uploaded online in industry-standard file formats with metadata for title and topical area, and automatically converts it into video data format compatible with the VOD content delivery system indexed by title and topical area. A User Interface for the system delivers listings data to the viewer's TV indexed by title and topical area, and displays a requested classified ad in response to viewer selection.

Provided is an adhesive composition for a protective film including an acrylic emulsion resin capable of providing contamination resistance on the film and low peel strength and minimizing generation of static electricity during peeling of the protective film. The acrylic emulsion resin includes a mixture including 80 to 99.9% by weight of a polymer of a (meth)acrylic acid ester monomer including a C1-C14 alkyl group and a (meth)acrylic acid ester monomer including an alkylene oxide unit, and 0.1 to 20% by weight of a monomer including a carboxyl group and/or a hydroxyl group or a combination thereof, and 5 to 30 parts by weight of a reactive emulsifier having a double bond structure radical-polymerizable with the polymer and including an alkylene oxide unit based on 100 parts by weight of the mixture.

This invention relates to whitlockite and a method for manufacturing the same. The method includes adding, to water, a calcium ion supplying material and a cation supplying material containing a cation (X) other than the calcium ion to prepare a cation aqueous solution, adding a phosphoric acid supplying material to the cation aqueous solution, and aging the cation aqueous solution including the phosphoric acid supplying material. As a result, whitlockite having high purity and high crystallinity can be mass produced using a simple process.

In one aspect, hollow nanoparticles are described herein. In some embodiments, a hollow nanoparticle comprises a metal shell and a cavity substantially defined by the shell, wherein the shell has a thickness greater than or equal to about 5 nm and the cavity has a curved surface. In another aspect, methods of making hollow nanoparticles are described herein. In some embodiments, a method of making hollow nanoparticles comprises forming a plurality of gas bubbles and forming a shell on the surface of at least one of the plurality of gas bubbles, wherein at least one of the gas bubbles is electrochemically generated. In another aspect, composite particles are described herein. In some embodiments, a composite particle comprises at least one nanoparticle and a polycrystalline metal shell substantially encapsulating at least one nanoparticle, wherein at least one surface of at least one nanoparticle is not in contact with the shell.

The invention relates to a glass item, at least one of the surfaces thereof having antimicrobial properties that are resistant to a temperature treatment, especially a temperature treatment in preparation of the subsequent tempering thereof. The glass item especially comprises an antimicrobial agent beneath the surface of the glass, and nanoparticles that are partially and/or totally incorporated into the mass of the glass close to said surface and consist of at least one inorganic component.

Disclosed is a hot-dip galvanized steel sheet or an alloyed hot-dip galvanized steel sheet, which has a tensile strength of 980 MPa or more, excellent workability, high yield ratio and high strength. The hot-dip galvanized steel sheet or the alloyed hot-dip galvanized steel sheet is characterized by containing 0.12-0.3% by mass of C, 0.1% by mass or less (excluding 0% by mass) of Si, 2.0-3.5% by mass of Mn, 0.05% by mass or less (excluding 0% by mass) of P, 0.05% by mass or less (excluding 0% by mass) of S, 0.005-0.1% by mass of Al and 0.015% by mass or less (excluding 0% by mass) of N, with the balance made up of iron and unavoidable impurities. The hot-dip galvanized steel sheet or the alloyed hot-dip galvanized steel sheet is also characterized in that the metallic structure thereof contains bainite as a matrix structure, and the area ratio of ferrite is 3-20% and the area ratio of martensite is 10-35% relative to the entire structure.

An OLED device comprises a cathode, an anode, and located therebetween a light-emitting layer containing a host material and a tris-C^N-cyclometallated complex of Ir or Rh wherein at least one of the ligands comprises a substituted quinazoline moiety. The device provides useful emission and stability attributes.

A heterocyclic compound represented by Formula 1 or Formula 2 below and an organic light-emitting device including the heterocyclic compound: wherein X1, X2, and R1 through R16 are defined as in the specification.

A perpendicular magnetic recording disk has a graded-anisotropy recording layer (RL) formed of at least two ferromagnetically exchange coupled CoPtCr-oxide magnetic layers (MAG1 and MAG2) with two nucleation films (NF1 and NF2) between the magnetic layers. NF1 is a metal film, preferably Ru or a Ru-based alloy like RuCr, sputter deposited on MAG1 at low pressure to a thickness between about 0.1-1.5 nm. NF2 is a metal oxide film, preferably an oxide of Ta, sputter deposited on NF1 at high pressure to a thickness between about 0.2-1.0 nm. MAG2 is sputter deposited over NF2. NF1 and NF2 provide a significant reduction in average grain size in the RL from a graded-anisotropy RL without nucleation films between MAG1 and MAG2, while also assuring that MAG1 and MAG2 are strongly exchange coupled.

A novel substance with which an increase in life and emission efficiency of a light-emitting element can be achieved is provided. A carbazole compound having a structure represented by General Formula (G1) is provided. Note that a substituent which makes the HOMO level and the LUMO level of a compound in which a bond of the substituent is substituted with hydrogen deep and shallow, respectively is used as each of substituents in General Formula (G1) (R1, R2, Ar3, and α3). Further, a substituent which makes the band gap (Bg) and the T1 level of a compound in which a bond of the substituent is substituted with hydrogen wide and high is used as each of the substituents in General Formula (G1) (R1, R2, Ar3, and α3).

In some embodiments, an improved mechanical adhesion of copper metallization to dielectric with partially cured epoxy fillers is presented. In this regard, a substrate build-up film is introduced having epoxy material and a plurality of epoxy microspheres, wherein an interior of the microspheres is not fully cured. Other embodiments are also disclosed and claimed.

A liquid crystalline polyester composition containing at least 100 parts by weight of liquid crystalline polyester (A) and 10 to 100 parts by weight of talc (B). The talc (B) has a ratio (a1/a2) of oil absorption (a1) ml/100 g to specific surface area (a2) m2/g in a range of 14.0 to 26.0 (ml·g)/(100 g·m2) and has a number-average particle diameter of 10 to 30 μm.