la The Association Between Poor Glycemic Control and Health Care Costs in People With Diabetes: A Population-Based Study By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To analyze the differences in health care costs according to glycemic control in people with type 2 diabetes. RESEARCH DESIGN AND METHODS Data on health care resource utilization from 100,391 people with type 2 diabetes were extracted from the electronic database used at the Catalan Health Institute. Multivariate regression models were carried out to test the impact of glycemic control (HbA1c) on total health care, hospital admission, and medication costs; model 1 adjusted for a variety of covariates, and model 2 also included micro- and macrovascular complications. Glycemic control was classified as good for HbA1c <7%, fair for ≥7% to <8%, poor for ≥8% to <10%, and very poor for ≥10%. RESULTS Mean per patient annual direct medical costs were 3,039 ± SD 6,581. Worse glycemic control was associated with higher total health care costs: compared with good glycemic control, health care costs increased by 18% (509.82) and 23% (661.35) in patients with very poor and poor glycemic control, respectively, when unadjusted and by 428.3 and 395.1, respectively, in model 2. Medication costs increased by 12% in patients with fair control and by 28% in those with very poor control (model 2). Patients with poor control had a higher probability of hospitalization than those with good control (5% in model 2) and a greater average cost when hospitalization occurred (811). CONCLUSIONS Poor glycemic control was directly related to higher total health care, hospitalization, and medication costs. Preventive strategies and good glycemic control in people with type 2 diabetes could reduce the economic impact associated with this disease. Full Article
la Diabetic Neuropathy Is a Substantial Burden in People With Type 1 Diabetes and Is Strongly Associated With Socioeconomic Disadvantage: A Population-Representative Study From Scotland By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To assess the contemporaneous prevalence of diabetic peripheral neuropathy (DPN) in people with type 1 diabetes (T1D) in Scotland and study its cross-sectional association with risk factors and other diabetic complications. RESEARCH DESIGN AND METHODS We analyzed data from a large representative sample of adults with T1D (N = 5,558). We assessed the presence of symptomatic neuropathy using the dichotomized (≥4) Michigan Neuropathy Screening Instrument Patient Questionnaire score. Logistic regression models were used to investigate associations between DPN and risk factors, as well as with other complications. RESULTS The burden of DPN is substantial with 13% prevalence overall. Adjusting for attained age, diabetes duration, and sex, the odds of DPN increased mainly with waist-to-hip ratio, lipids, poor glycemic control (odds ratio 1.51 [95% CI 1.21–1.89] for levels of 75 vs. 53 mmol/mol), ever versus never smoking (1.67 [1.37–2.03]), and worse renal function (1.96 [1.03–3.74] for estimated glomerular filtration rate levels <30 vs. ≥90 mL/min/1.73 m2). The odds significantly decreased with higher HDL cholesterol (0.77 [0.66–0.89] per mmol/L). Living in more deprived areas was associated with DPN (2.17 [1.78–2.65]) for more versus less deprived areas adjusted for other risk factors. Finally, individuals with prevalent DPN were much more likely than others to have other diabetes complications. CONCLUSIONS Diabetic neuropathy remains substantial, particularly affecting those in the most socioeconomically deprived groups. Those with clinically manifest neuropathy also have a higher burden of other complications and elevated levels of modifiable risk factors. These data suggest that there is considerable scope to reduce neuropathy rates and narrow the socioeconomic differential by better risk factor control. Full Article
la Escaped emu found playing in sprinkler one day later By www.upi.com Published On :: Wed, 06 May 2020 13:12:30 -0400 A Michigan family said their 6-foot-tall emu was found playing in another resident's sprinkler about a mile from home one day after escaping. Full Article
la Watch: Large flock of migrating birds shows up on Florida weather radar By www.upi.com Published On :: Wed, 06 May 2020 13:36:16 -0400 A Florida TV station's weather radar detected a large mass between the state and Cuba that turned out to be something other than an unseasonable storm -- it was a flock of migrating birds. Full Article
la Wallaby found wandering British countryside after zoo escape By www.upi.com Published On :: Thu, 07 May 2020 10:56:23 -0400 Police in Britain said a surprised jogger tipped officers off to the location of a wallaby that escaped from a zoo and went hopping through the countryside. Full Article
la Watch: Utah man reunited with class ring 38 years after it was lost in Germany By www.upi.com Published On :: Thu, 07 May 2020 15:42:56 -0400 A Utah man who lost his high school class ring in Germany in 1982 was reunited with the ring thanks to a man who found it on a beach in the United States. Full Article
la Watch: Bear makes late-night visit to Minnesota mall By www.upi.com Published On :: Fri, 08 May 2020 12:31:34 -0400 A security guard at a Minnesota mall that's currently closed to the COVID-19 pandemic captured photos and video of his encounter with a bear that went window-shopping for pasta. Full Article
la 16th Annual Immigration Law and Policy Conference By www.migrationpolicy.org Published On :: Tue, 28 May 2019 12:18:53 -0400 The 16th annual conference features thoughtful policy and legal analysis and discussion of the most important immigration topics from leading government officials, attorneys, researchers, advocates, and others. Full Article
la Colts QB Philip Rivers to coach at Alabama high school once NFL career ends By www.upi.com Published On :: Fri, 08 May 2020 21:04:31 -0400 Indianapolis Colts quarterback Philip Rivers will become the head football coach at St. Michael Catholic High School, the school announced Friday. Full Article
la Planet already seeing temps beyond human tolerability By www.upi.com Published On :: Sat, 09 May 2020 04:42:06 -0400 Researchers have predicted that if climate change goes unabated, the planet will experience intolerable heat in several decades. But a new study has found that in certain global hot spots, it's already happening. Full Article
la Lipid and Inflammatory Cardiovascular Risk Worsens Over 3 Years in Youth With Type 2 Diabetes: The TODAY clinical trial By care.diabetesjournals.org Published On :: 2013-06-01 TODAY Study GroupJun 1, 2013; 36:1758-1764TODAY Study Full Article
la Kidney Disease and Related Findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study By care.diabetesjournals.org Published On :: 2014-01-01 Ian H. de BoerJan 1, 2014; 37:24-30DCCT/EDIC 30th Anniversary Summary Findings Full Article
la New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 2 Diabetes Using Oral Agents and Basal Insulin: Glucose Control and Hypoglycemia in a 6-Month Randomized Controlled Trial (EDITION 2) By care.diabetesjournals.org Published On :: 2014-12-01 Hannele Yki-JärvinenDec 1, 2014; 37:3235-3243Emerging Technologies and Therapeutics Full Article
la Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia By care.diabetesjournals.org Published On :: 2016-07-01 Bernhard J. HeringJul 1, 2016; 39:1230-1240Emerging Technologies and Therapeutics Full Article
la The Fallacy of Average: How Using HbA1c Alone to Assess Glycemic Control Can Be Misleading By care.diabetesjournals.org Published On :: 2017-08-01 Roy W. BeckAug 1, 2017; 40:994-999Perspectives in Care Full Article
la Framingham, SCORE, and DECODE Risk Equations Do Not Provide Reliable Cardiovascular Risk Estimates in Type 2 Diabetes By care.diabetesjournals.org Published On :: 2007-05-01 Ruth L. ColemanMay 1, 2007; 30:1292-1293BR Cardiovascular and Metabolic Risk Full Article
la Exploring the Potential of the SGLT2 Inhibitor Dapagliflozin in Type 1 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Pilot Study By care.diabetesjournals.org Published On :: 2015-03-01 Robert R. HenryMar 1, 2015; 38:412-419Evolving Tactics With Inhibition of Sodium-Glucose Cotransporters Full Article
la Vitamin E Reduction of Protein Glycosylation in Diabetes: New Prospect for Prevention of Diabetic Complications? By care.diabetesjournals.org Published On :: 1991-01-01 Antonio CerielloJan 1, 1991; 14:68-72Short Report Full Article
la Early Signs of Cardiovascular Disease in Youth With Obesity and Type 2 Diabetes By care.diabetesjournals.org Published On :: 2005-05-01 Neslihan GungorMay 1, 2005; 28:1219-1221BR Pathophysiology/Complications Full Article
la Empagliflozin as Add-On to Metformin in Patients With Type 2 Diabetes: A 24-Week, Randomized, Double-Blind, Placebo-Controlled Trial By care.diabetesjournals.org Published On :: 2014-06-01 Hans-Ulrich HäringJun 1, 2014; 37:1650-1659Emerging Technologies and Therapeutics Full Article
la Serum 25-Hydroxyvitamin D3 Concentrations and Prevalence of Cardiovascular Disease Among Type 2 Diabetic Patients By care.diabetesjournals.org Published On :: 2006-03-01 Massimo CigoliniMar 1, 2006; 29:722-724BR Cardiovascular and Metabolic Risk Full Article
la Update on Cardiovascular Outcomes at 30 Years of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study By care.diabetesjournals.org Published On :: 2014-01-01 John M. LachinJan 1, 2014; 37:39-43DCCT/EDIC 30th Anniversary Summary Findings Full Article
la New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 2 Diabetes Using Basal and Mealtime Insulin: Glucose Control and Hypoglycemia in a 6-Month Randomized Controlled Trial (EDITION 1) By care.diabetesjournals.org Published On :: 2014-10-01 Matthew C. RiddleOct 1, 2014; 37:2755-2762Emerging Technologies and Therapeutics Full Article
la Neuropathy and Related Findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study By care.diabetesjournals.org Published On :: 2014-01-01 Catherine L. MartinJan 1, 2014; 37:31-38DCCT/EDIC 30th Anniversary Summary Findings Full Article
la Sodium-Glucose Cotransporter 2 Inhibition and Glycemic Control in Type 1 Diabetes: Results of an 8-Week Open-Label Proof-of-Concept Trial By care.diabetesjournals.org Published On :: 2014-05-01 Bruce A. PerkinsMay 1, 2014; 37:1480-1483Novel Communications in Diabetes Full Article
la Relationship Between {beta}-Cell Mass and Fasting Blood Glucose Concentration in Humans By care.diabetesjournals.org Published On :: 2006-03-01 Robert A. RitzelMar 1, 2006; 29:717-718BR Pathophysiology/Complications Full Article
la Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association By care.diabetesjournals.org Published On :: 2015-09-01 Caroline S. FoxSep 1, 2015; 38:1777-1803Scientific Statement Full Article
la Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From a Diabetes Care Editors Expert Forum By care.diabetesjournals.org Published On :: 2018-01-01 William T. CefaluJan 1, 2018; 41:14-31Diabetes Care Expert Forum Full Article
la Type 1 Diabetes Mellitus and Cardiovascular Disease: A Scientific Statement From the American Heart Association and American Diabetes Association By care.diabetesjournals.org Published On :: 2014-10-01 Sarah D. de FerrantiOct 1, 2014; 37:2843-2863Scientific Statement Full Article
la Lipoprotein Physiology in Nondiabetic and Diabetic States: Relationship to Atherogenesis By care.diabetesjournals.org Published On :: 1991-09-01 Henry N GinsbergSep 1, 1991; 14:839-855Diet and Diabetes Full Article
la HbA1c Levels Are Significantly Lower in Early and Late Pregnancy By care.diabetesjournals.org Published On :: 2004-05-01 Lene R. NielsenMay 1, 2004; 27:1200-1201Brief Reports Full Article
la Intensive Diabetes Treatment and Cardiovascular Outcomes in Type 1 Diabetes: The DCCT/EDIC Study 30-Year Follow-up By care.diabetesjournals.org Published On :: 2016-05-01 The Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research GroupMay 1, 2016; 39:686-693Cardiovascular Disease and Diabetes Full Article
la Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study? A Unifying Hypothesis By care.diabetesjournals.org Published On :: 2016-07-01 Sunder MudaliarJul 1, 2016; 39:1115-1122Diabetes Care Symposium Full Article
la Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010 By care.diabetesjournals.org Published On :: 2012-07-01 Franca B. BartonJul 1, 2012; 35:1436-1445Diabetes Care Symposium Full Article
la Relationship of Glucose Tolerance and Plasma Insulin to the Incidence of Coronary Heart Disease: Results from Two Population Studies in Finland By care.diabetesjournals.org Published On :: 1979-03-01 Kalevi PyöräläMar 1, 1979; 2:131-141Proceedings of the Kroc Foundation International Conference on Epidemiology of Diabetes and its Macrovascular Complications Full Article
la Coronary Heart Disease Incidence and Cardiovascular Mortality in Busselton with Reference to Glucose and Insulin Concentrations By care.diabetesjournals.org Published On :: 1979-03-01 T A WelbornMar 1, 1979; 2:154-160Proceedings of the Kroc Foundation International Conference on Epidemiology of Diabetes and its Macrovascular Complications Full Article
la Prevalence and Determinants of Glucose Intolerance in a Dutch Caucasian Population: The Hoorn Study By care.diabetesjournals.org Published On :: 1995-09-01 Johanna M MooySep 1, 1995; 18:1270-1273Short Report Full Article
la Hyperglycemie and Microvascular and Macrovascular Disease in Diabetes By care.diabetesjournals.org Published On :: 1995-02-01 Ronald KleinFeb 1, 1995; 18:258-268Kelly West Lecture 1994 Full Article
la Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham Study By care.diabetesjournals.org Published On :: 1979-03-01 W B KannelMar 1, 1979; 2:120-126Proceedings of the Kroc Foundation International Conference on Epidemiology of Diabetes and its Macrovascular Complications Full Article
la Latin American business leaders optimistic about region’s post-pandemic economy By www.upi.com Published On :: Wed, 06 May 2020 18:44:51 -0400 Despite worrying economic projections, business leaders in Latin America remain optimistic about post-pandemic economy. Full Article
la Gas leak at India chemical plant kills 8, sickens hundreds By www.upi.com Published On :: Thu, 07 May 2020 03:34:34 -0400 At least eight people died and hundreds were hospitalized after toxic gas leaked from a chemical factory in southern India early Thursday, officials said. Full Article
la Bank of England: British economy could decline 14 percent By www.upi.com Published On :: Thu, 07 May 2020 07:29:45 -0400 A Bank of England report said Thursday the British economy could fall as much as 14 percent this year, which would be its worst showing in more than 300 years. Full Article
la Report: South Korea tested new ballistic missile with larger warhead By www.upi.com Published On :: Thu, 07 May 2020 09:35:46 -0400 South Korea's military tested a ballistic missile capable of carrying a 2-ton warhead in March, according to local reports on Thursday. Full Article
la Google-related company pulls plug on Toronto 'smart city' project By www.upi.com Published On :: Thu, 07 May 2020 13:41:47 -0400 A Google-related company has pulled the plug on its ambitious high-tech waterfront city project in Toronto, citing financial strains from the coronavirus, but the project had also run into local opposition. Full Article
la More than 70 dead in Rwanda after floods, landslides By www.upi.com Published On :: Fri, 08 May 2020 11:29:22 -0400 Heavy rains, flash flooding and landslides have led to the deaths of more than 70 people in Rwanda, officials said Friday. Full Article
la Northrop Grumman awarded $123.5M to integrate Navy LAIRCM system By www.upi.com Published On :: Fri, 01 May 2020 19:14:31 -0400 Northrop Grumman received a $123.5 million contract modification Friday to integrate the Department of Navy Large Aircraft Infrared Countermeasures system onto aircraft for the U.S. military and two allied governments. Full Article
la Blue Angels to fly over Dallas, Houston, New Orleans on Wednesday By www.upi.com Published On :: Tue, 05 May 2020 13:47:57 -0400 The U.S. Navy Flight Demonstration Squadron, also known as the Blue Angels, will fly over Dallas/Fort Worth, Houston and New Orleans Wednesday to honor frontline workers fighting the COVID-19 pandemic. Full Article
la DoD releases name of soldier who died in 'non-combat-related' incident in Iraq By www.upi.com Published On :: Tue, 05 May 2020 17:38:37 -0400 The Pentagon announced Tuesday that Sgt. Christopher Wesley Curry died Monday in Iraq in what officials describe as a non-combat-related incident. Full Article
la Air Force sets May 16 launch for X-37B spy plane By www.upi.com Published On :: Wed, 06 May 2020 14:16:56 -0400 The Air Force said Wednesday it will launch the sixth mission of the uncrewed X-37B spy plane May 16 from Florida with a record number of experiments on board. Full Article
la Navy breaks ground on laser weapons test lab in California By www.upi.com Published On :: Thu, 07 May 2020 18:29:45 -0400 Navy leaders and private contractors broke ground this week on what will become the fleet's only dedicated facility to test, fire and evaluate complete laser weapon systems in a maritime environment. Full Article
