wit Tips for Getting Started with a Business Growth Framework By blog.avangate.com Published On :: Tue, 26 Mar 2019 00:00:00 +0000 Growth is top of mind for most companies, but it can be tricky to get started with developing a growth framework. For one thing, most companies aren’t organized around growth, so thinking about growth requires a lot of collaboration between teams. Additionally, companies often don’t have easy access to all of the data they need to understand growth. Full Article
wit News24 | Business as usual at Lebombo border post with traffic flowing between SA and Mozambique after unrest By www.news24.com Published On :: Saturday Nov 09 2024 12:26:31 It was business as usual at the Lebombo border post between SA and Mozambique on Saturday morning, with vehicles moving freely between both countries after a shutdown earlier this week. Full Article
wit News24 | Africa has other friends if Trump won't work with it - Kenya's AU candidate By www.news24.com Published On :: Saturday Nov 09 2024 18:36:48 Kenya's candidate for the top job at the African Union said on Saturday that if US president-elect Donald Trump does not want to work with Africa, the continent has "other friends". Full Article
wit News24 | UPDATE 1-Mauritius holds election with cost of living on everyone's minds By www.news24.com Published On :: Monday Jan 01 0001 00:00:00 PORT LOUIS, Nov 10 - Mauritius was holding a parliamentary election on Sunday with Prime Minister Pravind Kumar Jugnauth and his main rivals all promising to tackle a cost of living crisis in the Indian Ocean archipelago. Full Article
wit In Harmony with Nature By www.readingrockets.org Published On :: Wed, 24 Aug 2022 14:29:35 EDT My father, the birder, is often excited to share his sightings with me — especially so this summer when he got back from a long-planned trip to South Africa. 153 species! I love how he finds joy and peace by connecting with the world through observing birds, interacting with fellow birders, and telling tales of his birding adventures. In so many wonderful ways, Dad’s daily routines and way of life are linked to nature and the birds he loves. Full Article
wit Current State of the Evidence: Examining the Effects of Orton-Gillingham Reading Interventions for Students With or at Risk for Word-Level Reading Disabilities By www.readingrockets.org Published On :: Tue, 11 Oct 2022 10:40:37 EDT Over the past decade, parent advocacy groups led a grassroots movement resulting in most states adopting dyslexia-specific legislation, with many states mandating the use of the Orton-Gillingham (OG) approach to reading instruction. Orton-Gillingham is a direct, explicit, multisensory, structured, sequential, diagnostic, and prescriptive approach to reading for students with or at risk for word-level reading disabilities (WLRD). Evidence from a prior synthesis and What Works Clearinghouse reports yielded findings lacking support for the effectiveness of OG interventions. Full Article
wit Won’t Student Motivation Be Damaged If We Teach with Complex Text? By www.readingrockets.org Published On :: Wed, 12 Oct 2022 09:31:58 EDT Teacher question: I understand your claims that teaching students with grade-level texts instead of instructional level texts increases children’s opportunities to learn. However, what about children’s emotional needs, self-esteem, motivation, and self-starting skills when text is challenging. Children who struggle with sight words or sounding out words who are given a hard piece of text will shut down and refuse to try or will act out in the classroom. Full Article
wit Upgraded: Stopovers in Istanbul, with free tours courtesy of Turkish Airlines By www.upgradetravelbetter.com Published On :: Thu, 24 Feb 2011 07:40:04 +0000 Sure, some airlines let you work in a free stopover. But Turkish Airlines goes one step further and offers up a free city tour on a stopover as short as six hours. Maybe getting into a shuttle bus and tooling around Istanbul after seven hours on an Airbus isn’t your cup of tea, but if […] The post Upgraded: Stopovers in Istanbul, with free tours courtesy of Turkish Airlines first appeared on UPGRADE: TRAVEL BETTER. Full Article Travel
wit Top 3 Airports With Casinos By www.upgradetravelbetter.com Published On :: Sat, 27 May 2017 08:03:32 +0000 Have you ever been at an airport waiting to connect your flight for hours on end? We all have, and yeah, it always blows to twiddle your thumbs for hours waiting for a flight that might delay or not. Aside from drinking mugs after mugs of coffee, there really doesn’t seem to be much one […] The post Top 3 Airports With Casinos first appeared on UPGRADE: TRAVEL BETTER. Full Article Travel
wit AI / Deep Learning applications course – with hands-on experience By www.opengardensblog.futuretext.com Published On :: Mon, 26 Mar 2018 12:04:04 +0000 New workshop in London / remote Link - Enterprise AI workshop – Sep 2018 – in London or remote AI / Deep Learning applications course/ mentoring program – hands-on experience with limited spaces I am pleased to announce a new course on AI Applications The course combines elements of teaching, coaching and [...] Full Article BIG DATA FEATURED POSTS LATEST POSTS
wit AI labs – a club for #AI research and a chance to gain hands-on experience with AI By www.opengardensblog.futuretext.com Published On :: Wed, 07 Nov 2018 06:35:22 +0000 We have been working on this idea over the summer and have now launched the next stage of the AI labs in London Here are some more details. Think of AI labs – as a club for AI research AI labs addresses three problems a) Today, even if you are working on Machine Learning [...] Full Article BIG DATA FEATURED POSTS LATEST POSTS
wit How to read a book a week in the age of Facebook and twitter By www.opengardensblog.futuretext.com Published On :: Wed, 07 Nov 2018 22:08:25 +0000 Background When my son was nearing 14 years, I mentioned to him that I read James Clavell’s epic novel Shogun (1136 pages) around the age of 15 i.e. his age. Reading a book like Shogun at age 15 is admittedly not typical reading for a 15-year-old. But I have always been an avid reader [...] Full Article BIG DATA FEATURED POSTS LATEST POSTS
wit Amazon readies new AI chip to compete with Nvidia By readwrite.com Published On :: Tue, 12 Nov 2024 12:56:28 +0000 Nvidia might have some serious competition in the AI chip space coming. Amazon is now seeking to bring its own… Continue reading Amazon readies new AI chip to compete with Nvidia The post Amazon readies new AI chip to compete with Nvidia appeared first on ReadWrite. Full Article Big Tech Technology Amazon ChatGPT Nvidia
wit Brighter Shores infinite money glitch – get cash rich with all the money you will ever need By readwrite.com Published On :: Tue, 12 Nov 2024 13:20:45 +0000 If you are the type of person that likes to spoil a game from the off then Brighter Shores is… Continue reading Brighter Shores infinite money glitch – get cash rich with all the money you will ever need The post Brighter Shores infinite money glitch – get cash rich with all the money you will ever need appeared first on ReadWrite. Full Article Gaming Brighter Shores
wit LG gives glimpse into the future with stretchy display By readwrite.com Published On :: Tue, 12 Nov 2024 16:24:25 +0000 LG’s latest prototype screen is stretchy. Shown off at LG’s Science Park in Seoul, the company demonstrated the new type… Continue reading LG gives glimpse into the future with stretchy display The post LG gives glimpse into the future with stretchy display appeared first on ReadWrite. Full Article Gadgets LG
wit Dogecoin at the Edge of a Major Breakout – Could $2 Be Possible with Bitcoin Dominance Holding Strong? By readwrite.com Published On :: Tue, 12 Nov 2024 18:38:36 +0000 Dogecoin has experienced a significant surge in value since last month, with impressive price gains continuing today as it trades… Continue reading Dogecoin at the Edge of a Major Breakout – Could $2 Be Possible with Bitcoin Dominance Holding Strong? The post Dogecoin at the Edge of a Major Breakout – Could $2 Be Possible with Bitcoin Dominance Holding Strong? appeared first on ReadWrite. Full Article Cryptocurrency
wit News24 Business | Microsoft beefs-up its AI assistant with voice, vision By www.news24.com Published On :: Thursday Oct 03 2024 12:31:25 Microsoft on Tuesday doubled down on deploying artificial intelligence to consumers, releasing an updated version of its Copilot chatbot that can hold voice conversations and interpret images. Full Article
wit News24 | Wednesday's weather: Severe weather predicted in parts of the country with multiple warnings issued By www.news24.com Published On :: Tuesday Nov 12 2024 18:36:01 The country is set to experience varied weather conditions, with several impact-based warnings issued across various provinces, according to the South African Weather Service. Full Article
wit News24 | Patients lie on the floor at Uitenhage hospital - some with serious injuries By www.news24.com Published On :: Tuesday Nov 12 2024 19:38:05 Patients lie on the floor at Uitenhage Provincial Hospital in Kariega, some with drips in their veins. Full Article
wit News24 | SA Jewish Board of Deputies approaches Equality Court with social media hate speech complaint By www.news24.com Published On :: Wednesday Nov 13 2024 08:11:04 The Cape South African Jewish Board of Deputies has asked the Equality Court in Cape Town to declare politician Mehmet Vefa Dag's social media posts about about Jewish people hate speech. Full Article
wit News24 | Higher education minister clashes with NSFAS head over 'unexplained' suspension of 2 officials By www.news24.com Published On :: Wednesday Nov 13 2024 06:16:50 A formal disciplinary process, or lack thereof, around the suspensions of two high-ranking officials at the National Student Financial Aid Scheme (NSFAS) has pitted Higher Education and Training Minister Nobuhle Pamela Nkabane against NSFAS administrator Freeman Nomvalo. Full Article
wit News24 | Inside Gauteng legislature's shadowy deal with employees accused of fraud during Covid-19 spree By www.news24.com Published On :: Wednesday Nov 13 2024 04:45:15 Gauteng legislature secretary Linda Mwale has signed a sweetheart agreement with Nehawu to let 32 employees accused of defrauding the institution off the hook. Full Article
wit How We Travel with a Cat in Our Tiny 17' Casita Travel Trailer By vagabondish.com Published On :: Wed, 09 Dec 2020 16:08:22 +0000 Traveling with dogs is easy; cats not so much. Here's everything we've learned about traveling with cats in a travel trailer or RV. The post How We Travel with a Cat in Our Tiny 17′ Casita Travel Trailer appeared first on Vagabondish. Full Article Features RV Travel
wit "Laptop" with full 4090 GPU weighs 15 pounds By boingboing.net Published On :: Tue, 01 Oct 2024 16:25:57 +0000 There are laptops sold with NVidia's high-end 4090 graphics chip, but it's a power-constrained mobile version appropriate for portable machines. A Chinese-language blogger modded themselves a beast of a machine with a full desktop-class 4090 card. This thing weighs 15 pounds and its battery life is a Borgesian map of nothing (one must plug it in). — Read the rest The post "Laptop" with full 4090 GPU weighs 15 pounds appeared first on Boing Boing. Full Article Post computers gadgets hacks
wit Interactive Media Strategies believes Microsoft could win big with Skype By communicationtransformation.blogspot.com Published On :: Fri, 13 May 2011 22:01:00 +0000 Interactive Media Strategies (IMS) is a market research firm that follows streaming media. They discuss the news of Microsoft’s $8.5 billion acquisition of Skype, and the prospects for Skype to emerge as a viable platform for business video communications. Their research compares usage levels for a range of social media and communications applications, including Skype, YouTube and Facebook. Here is a link to the video. They report that personal use of Facebook and YouTube is relatively high but that has not yet translated into comparable levels of corporate use. They believe this raises the question of whether YouTube and Facebook will be able to outgrow their focus on the consumer side of the business to compete in the enterprise market. Usage levels for Skype are significantly lower overall, but Skype’s penetration in business communications is higher than they see for other communications apps online among young users most likely to experiment with emerging technologies. IMS puts forth the opinion that if Microsoft could make it easier for technology laggards to embrace Skype - i.e. integrate Skype with the Microsoft Office suite - then Skype could achieve significant enterprise adoption. Full Article
wit Teacher at Chino Valley School District Goes Off the Rails over a Student With a Trump Hat By conservativefiringline.com Published On :: Mon, 11 Nov 2024 19:14:43 +0000 The following article, Teacher at Chino Valley School District Goes Off the Rails over a Student With a Trump Hat, was first published on Conservative Firing Line. A “teacher” at Chino Valley School District launched into an unhinged rant after a student entered his classroom wearing a Trump hat. His name is Clyde J Colinco, who is also the girls golf course, and unfortunately, he still appears to be employed at Chino High School. “Trump Derangement Syndrome is a real thing. If … Continue reading Teacher at Chino Valley School District Goes Off the Rails over a Student With a Trump Hat ... Full Article Opinion Politics C J Colinco Chino Valley golf coach teacher rant Trump hat
wit Major Ruling In CNN Defamation Fight With James O’Keefe (Video) By conservativefiringline.com Published On :: Tue, 12 Nov 2024 18:15:00 +0000 The following article, Major Ruling In CNN Defamation Fight With James O’Keefe (Video), was first published on Conservative Firing Line. A federal appeals court has ruled against CNN in its attempt to have dismissed a defamation complaint from James O’Keefe and Project Veritas. O’Keefe launched Project Veritas and worked years with the organization, doing undercover interviews to uncover political scandals. He later left and now works with O’Keefe Media Group. But the dispute arose during … Continue reading Major Ruling In CNN Defamation Fight With James O’Keefe (Video) ... Full Article Politics CNN defamation lawsuit O'Keefe Veritas
wit "Back to Work" - Merlin's New Thing with Dan Benjamin at 5by5.tv By www.43folders.com Published On :: Tue, 18 Jan 2011 16:15:15 +0000 [update 2011-01-18 @ 16:07:40: We're up!] 5by5 Live Before Christ was a corporal, Dan Benjamin was already a bit of a hero to me. Since the early aughts–long before his insanely great 5by5.tv podcast network–Dan’s Hivelogic Enkoder was saving us millions of spam messages. His thoughtful tutorials on OS X (including unmissable advice on doing sane installs of MySQL and Rails, among others) are among the best on the web. His CSS has been widely stolen and reused without acknowledgment by thieves as diverse as other people and me. And his polymath posts on everything from Buddhism to The Paleo Diet to how to record a “Double-ender” have shown a charming combination of curiosity and empathy that, amongst numerous other reasons, clearly makes Dan a better human than me. A propos of nothing, Dan’s also the guy who conducted one of (mp3) the three best interviews with me in which it’s been my good fortune to participate.1 Today, I’m honored to say that Dan and I are starting a thing together. If it suits you, drop by 5by5.tv/live in about 35 minutes–at Noon Eastern/9am Pacific–to find out what we’re up to. I think it might be good. I’ll just say I’m as excited about this as I’ve been about any new project I’ve started in the past year or so. Anyway. You can judge for yourself. Whether you can tolerate me or otherwise, definitely do not miss the work Dan’s doing at 5by5. Because it really is outstanding and very polished stuff. As for our thing? My own goal, to paraphrase a bit from that interview with Dan, is to help you get excited, get better–and then?–Back to Work. More soon. Thanks. Favorite interviews. Just for the sake of completion, my all-time favorite interview was conducted by Colin Marshall for The Marketplace of Ideas (mp3); Dan’s “The Pipeline” eppy with me was a close second; and David and Katie’s recent nerderrific interview on my Mac workflow (mp3) on Mac Power Users has turned out to be a lot of peoples’ favorite thing I’ve done in years (love LOVE David’s stuff). ↩ And...we're up Back to Work | Ep.#1: Alligator in the Bathroom Download MP3 of "'Back to Work,' Ep. 1" In the inaugural episode of Back to Work, Merlin Mann and Dan Benjamin discuss why they’re doing this show, getting back to work instead of buying berets, the lizard brain, and compare the Shadow of the Mouse to San Francisco, and eventually get to some practical tips for removing friction. It's a start. Sexy Audio RSS Feed Sexy Subscription via iTunes Episode Links Welcome to BrettTerpstra.com, home of Brett Terpstra and his nerdery carlhuda/janus – GitHub practically efficient — technology, workflows, life MacSparky – Blog The Brooks Review And now it’s all this Dan Rodney’s List of Mac OS X Keyboard Shortcuts & Keystrokes 43f Podcast: John Gruber & Merlin Mann’s Blogging Panel at SxSW | 43 Folders waffle software · ThisService One Thing Well html2text: THE ASCIINATOR (aka html2txt) The Conversation #27: Missionless Statements – 5by5 ”"Back to Work" - Merlin's New Thing with Dan Benjamin at 5by5.tv” was written by Merlin Mann for 43Folders.com and was originally posted on January 18, 2011. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article hacer pimping Podcasts
wit Wrestling With The Gray Lady By battellemedia.com Published On :: Tue, 30 Apr 2024 18:16:16 +0000 The other day my wife and I heard a report on our local public radio station that mentioned the Biden Administration’s American Climate Corps (ACC) initiative, a new program seeking to recruit 20,000 young people into jobs on the front line of the climate crisis. Modeled on Franklin Roosevelt’s Depression-Era Civilian Conservation Corps (CCC), the … Continue reading "Wrestling With The Gray Lady" Full Article Columns Joints After Midnight & Rants Life Media/Tech Business Models Random But Interesting The Conversation Economy climate change journalism media new york times
wit Consume First, Deal with the Shit Later By battellemedia.com Published On :: Tue, 30 Jul 2024 14:54:54 +0000 Websites are Blocking the Wrong AI Scrapers (Because AI Companies Keep Making New Ones) – 404 Media *** I had a call the other day with the Dean of a top-five school of public health, and in between furiously scribbling notes (yes, I still take notes), it struck me that here in the United States … Continue reading "Consume First, Deal with the Shit Later" Full Article The Web As Platform ai artificial intelligence data Internet policy
wit Former BLM Chapter Co-Founder Switches To Trump In ’24 … What Changed His Mind? By clashdaily.com Published On :: Tue, 05 Nov 2024 10:10:35 +0000 Mark Fisher was co-founder of the Rhode Island chapter of BLM. He voted for Joe Biden in 2020. Does he have buyers remorse? Yeah, you could say so. His viral video is causing a stir... but there's more to that story. The post Former BLM Chapter Co-Founder Switches To Trump In ’24 … What Changed His Mind? appeared first on Clash Daily. Full Article Videos
wit Sport | More to Bok prodigy Moodie after turbulence with Duhan and Co in Edinburgh By www.news24.com Published On :: Tuesday Nov 12 2024 06:12:02 Canan Moodie used his start against Scotland to show that he is about far more than just pace out wide and aerial ability. Full Article
wit Farahat with Sandy Rios in the Morning By cynthiafarahat.com Published On :: Fri, 28 Oct 2022 15:06:00 +0000 Originally posted on Oct 28, 2022 It was an honor to be interviewed by the beautiful and patriotic Sandy Rios about my book and my journey writing it on her show, “Sandy Rios In the Morning.” https://afr.net/podcasts/sandy-rios-in-the-morning/2022/october/cynthia-farahat-discusses-her-new-book-the-secret-apparatus-the-muslim-brotherhood-s-industry-of-death/ Full Article Featured Articles
wit One on One with John DeDakis By cynthiafarahat.com Published On :: Tue, 06 Dec 2022 10:35:47 +0000 One on One with John DeDakis, Dec. 4, 2022 My interview with the impressive John DeDakis. John DeDakis is a former CNN Senior Copy Editor and writer for the Emmy and Peabody-Award winning news program “The Situation Room with Wolf Blitzer” from 2005-2013. He is also the author of the Lara Chadwick Mystery series. DeDakis […] Full Article Featured Articles
wit Farahat’s Interview with FDD By cynthiafarahat.com Published On :: Wed, 11 Jan 2023 12:42:02 +0000 FDD’s Foreign Podicy Podcast with Cynthia Farahat Dec. 27, 2022 The Muslim Brotherhood has been around for close to a century but most people – certainly most Americans and Europeans – know very little about it. Is it reformist and non-violent as its spokesmen and defenders claim? Or is it – as Cynthia Farahat argues in a […] Full Article Featured Articles
wit Newsroom: TikTok Ad Revenues to Surpass Twitter and Snapchat Combined By www.emarketer.com Published On :: Mon, 11 Apr 2022 04:01:00 GMT Worldwide revenues will triple in 2022   April 11, 2022 (New York, NY) – TikTok’s worldwide ad revenues will triple this year and surpass that of two competitors combined, according […] Full Article
wit Newsroom: Twitter MAUs Set to Grow Just 1.5% This Year By www.emarketer.com Published On :: Tue, 10 May 2022 04:01:00 GMT May 10, 2022 (New York, NY) – Elon Musk has his work cut out for him as he takes the reigns at Twitter. Worldwide user growth will be essentially flat […] Full Article
wit Climate justice with Chinese characteristics? By www.chathamhouse.org Published On :: Mon, 07 Nov 2022 11:36:21 +0000 Climate justice with Chinese characteristics? Expert comment NCapeling 7 November 2022 China’s latest grand concept, the Global Development Initiative (GDI), claims to be making sustainability a key feature of the programme. Since joining the World Trade Organization (WTO) in 2001, China has regularly unveiled a grand new strategic concept every four years or so. Each has been deeply rooted in the Chinese political system and communicated via ambitious slogans, such as A Harmonious World, or New Types of Great Power Relations. And all have reliably generated both excitement and confusion abroad and within China. China’s latest grand concept, the Global Development Initiative (GDI), is no exception. When Chinese president Xi Jinping introduced it at the United Nations General Assembly (UNGA) in September 2021, it made hardly any splash in the West, perhaps because China has already signalled its determination to shape international development in the post-COVID era. But the GDI is more than just a new label for an ongoing project. One of its core political functions is to deflect some of the fierce criticism directed at its older sibling, the gigantic Belt and Road Initiative (BRI), which has a tarnished reputation for being neither transparent nor sufficiently ‘green’. Focus on grants and capacity-building According to the Chinese government’s initial description of the GDI, sustainability is a key feature of the programme. Unlike the BRI, the GDI will focus less on physical infrastructure projects – such as roads, bridges, digital networks, and coal-fired power plants – and more on sustainable-development grants and capacity-building. China may be ruled by one party, but that doesn’t mean its central administration system can always speak with one voice in supporting sustainable development abroad In his remarks about GDI in 2021, Xi placed special emphasis on advancing the UN Sustainable Development Goals (SDGs) and helping developing countries manage the transition to a low-carbon economy. On paper, then, the GDI appears a laudable initiative. While ongoing geopolitical tensions have deepened divisions between China and the US, derailing collaboration on combatting climate change, China at least is adjusting its diplomacy and aid programmes to position itself as a more attractive partner for those seeking climate security. Since launching the GDI, it has already created the China-Pacific Island Countries Climate Action Cooperation Centre to help some of the world’s most vulnerable countries mitigate the damage from climate change. But the GDI is still very much in line with China’s past grand initiatives. Its implementation is opaque and there is considerable flexibility in how it will deliver projects and offer grants. This approach is well understood and frequently practiced by Chinese political elites, following Deng Xiaoping’s famous reform ethos of ‘crossing the river by feeling the stones’. Xi has clearly adopted this approach in introducing the GDI. But whereas Deng was steering China’s domestic economy during a period of isolation after the Cultural Revolution, Xi needs to involve many other countries in his vision. That will not be easy now that Russia’s war in Ukraine and other recent developments have complicated many of China’s international relationships. China’s leaders recognize the BRI was not warmly received in global development circles, owing partly to its role in increasing both climate and financial risks. In implementing the GDI, they need to rethink some basic assumptions. Although gigantic infrastructure investments drove China’s own economic miracle, the same approach is not necessarily applicable everywhere. Nor should China’s development aid be relentlessly used to seek diplomatic endorsement from other countries. Instead, producing a clear, concrete action plan with specific regional and thematic points of focus would enhance the GDI’s clarity and credibility. Consider Xi’s recent pledge to add $1 billion to the $3.1 billion South-South Cooperation Assistance Fund, which will be renamed the Global Development and South-South Cooperation Fund. If China is serious about the GDI’s green credentials, this money should go towards supporting the clean-energy transition in response to the current oil and gas price crunch. But the GDI’s success ultimately depends on how China deploys not just financial but political capital. It needs to show it can cooperate constructively with countries in the ‘GDI Friends Group’ launched at the UN in January 2022. Producing a clear, concrete action plan with specific regional and thematic points of focus would enhance the GDI’s clarity and credibility For many group members, the pandemic showed that existing development assistance programs urgently need to be updated to account for their recipients’ specific interests and priorities. After years of hollow diplomatic rhetoric, there is a craving for more meaningful assistance to help countries build resilience against climate-driven natural disasters and other growing threats. China could help meet this demand, but it also will need to manage expectations. Many in the Global South assume a grand-concept policy such as the GDI will be meticulously planned from within Xi’s cabinet and thus executed to deliver large-scale, rapid results. But the GDI will require broad coordination across a wide range of ministries, agencies, and state-owned banks. One party but not one voice China may be ruled by one party, but that doesn’t mean its central administration system can always speak with one voice in supporting sustainable development abroad. Since launching the BRI in 2013, China has showered the Global South with hundreds of billions of dollars in physical infrastructure investment. With the global climate debate increasingly focusing on the need to mobilize international financing for climate mitigation and adaptation in low and middle-income countries, many will be looking to both China and the advanced economies to provide the necessary support. Full Article
wit In conversation with David Miliband: Finding a new approach to tackle conflict, climate and extreme poverty By www.chathamhouse.org Published On :: Thu, 15 Aug 2024 09:57:13 +0000 In conversation with David Miliband: Finding a new approach to tackle conflict, climate and extreme poverty 11 September 2024 — 5:00PM TO 5:45PM Anonymous (not verified) 15 August 2024 Chatham House and Online David Miliband discusses how the climate crisis, extreme poverty and conflict are becoming inextricably linked and how the global community must respond. Combatting the climate crisis, ending protracted conflicts, and alleviating poverty are three of the greatest priorities for international action. However, these three challenges become increasingly concentrated in a handful of countries. The subsequent feedback loop makes addressing these challenges even more complex.The International Rescue Committee’s (IRC’s) work in crisis-affected communities highlights this new geography of crisis. Just 16 countries, which are both climate-vulnerable and conflict-affected. This represents 43% of all people living in extreme poverty, 44% of all people affected by natural disasters and 79% of all people in humanitarian need. This trend towards the concentration of crisis is only deepening. In three decades, the number of conflict-affected, climate-vulnerable states has increased from 44% to more than two-thirds.Affected countries - like Sudan, Myanmar, and Syria - are also among the least supported financially. Debt burdens are siphoning away critical resources needed for adaptation and resilience. Humanitarian aid budgets are being slashed by donor governments. The private sector refuses to invest in these communities they view as too risky. And the international financial institutions meant to alleviate poverty and spur climate action are not well-designed to work with crisis-affected states or local communities. With the upcoming COP29 Summit in Azerbaijan focused on the New Collective Quantified Goal for climate finance, vulnerable communities will be watching closely whether they will get support in their fight against the worst impacts of the climate crisis.Conflict, the climate crisis, and extreme poverty are taking their toll. But how can the world best respond?Key questions to be discussed during the session include:At a time of political disruption, how does the West engage with vulnerable countries? What actions should be prioritised in providing support to such countries?Can global institutions evolve to better protect vulnerable and displaced people from conflict and climate-risk, particularly as geopolitical rivalries reduce space for cooperation?What is the UK’s role in supporting climate action in fragile states and how does this align with its agenda on the Sustainable Development Goals and extreme poverty? Full Article
wit In conversation with HRH Prince Turki AlFaisal By www.chathamhouse.org Published On :: Fri, 16 Aug 2024 09:27:14 +0000 In conversation with HRH Prince Turki AlFaisal 13 September 2024 — 11:00AM TO 12:00PM Anonymous (not verified) 16 August 2024 Chatham House and Online This event will discuss how the ongoing Gaza war is impacting the region and the role external actors can play to support de-escalation. The Gaza war, now in its tenth month, continues with ever-worsening consequences for Palestinians and no end in sight. The Israeli-Palestinian conflict has also heightened tensions across the Middle East with fears of a broader regional war that would include Iran and aligned groups from the ‘axis of resistance’.Against this backdrop, ceasefire negotiations supported by regional and international mediators, have not amounted to an agreement nor have there been any concrete proposals for a way forward out of the crisis by key actors such as the United States, Gulf countries or other key stakeholders.In this event, His Royal Highness Prince Turki AlFaisal will discuss how the Gaza war and related developments are impacting the Middle East, and will share his views on the role of regional and external actors in supporting de-escalation efforts.The addresses:How are Middle Eastern countries managing regional security and heightened tensions with Iran and aligned groups in Iraq, Lebanon and Yemen?What role are Gulf countries playing in efforts to de-escalate tensions?How can they support short- and long-term planning for a way forward in the Israeli-Palestinian conflict?How are relationships between Middle East countries and external powers such as the United States changing as a result of the Gaza war?In person places for this event are balloted. Confirmations will be sent by email on Monday 9 September at 3pm or a placed on the waiting list. Virtual registrations are confirmed immediately.Individual membership provides you with the complete Chatham House experience, connecting you with a unique global policy community. Find out more about membership. Full Article
wit In conversation with Valerii Zaluzhnyi, Ukrainian Ambassador to the UK By www.chathamhouse.org Published On :: Mon, 16 Sep 2024 19:47:13 +0000 In conversation with Valerii Zaluzhnyi, Ukrainian Ambassador to the UK 17 October 2024 — 10:00AM TO 11:00AM Anonymous (not verified) 16 September 2024 Chatham House and Online The former Commander-in-Chief of the Armed Forces of Ukraine offers insight into the evolution of Russia’s war against his country, and what to expect next. More than two and a half years since Russia launched its full-scale invasion, Ukraine has consistently adapted to Moscow’s advances by implementing new strategies.Ukraine’s recent incursion into Russia’s Kursk region demonstrated operational tactical ingenuity, surprising both Russia and Ukraine’s Western supporters. Success against the Russian Black Sea Fleet has already showcased how Ukraine can skilfully beat back Russian aggression. And increasing numbers of targeted strikes on Russian supply depots and airfields are disrupting Russian operations behind the front lines.Critical Western supplies continue to resource Ukraine’s military. But questions linger over the quantity and sustainability of these supplies. Kyiv will be watching the US presidential election in November as its biggest backer goes to the polls with the possibility of an outcome that could seriously affect the war. Meanwhile, Russian forces continue to edge forward in Donbas, despite heavy casualties, and strike at Ukrainian towns and cities from the air, demonstrating that President Putin has no intention of relinquishing the fight.Amid these complexities, Ambassador Zaluzhnyi will discuss how the war is changing both sides, advances on the battlefield, and what dangers lie ahead for Ukraine in the coming months. Other key questions include:What kind of enemy is Russia today and how to secure its strategic defeat in Ukraine;How have new strategies, such as the recent incursion into the Kursk region, affected the state of play on the battlefield?What technologies and armaments does Ukraine need from its Western allies in both the short and long term?Individual membership provides you with the complete Chatham House experience, connecting you with a unique global policy community. Find out more about membership. Full Article
wit In conversation with Martin Griffiths: How can a divided world address conflict? By www.chathamhouse.org Published On :: Mon, 16 Sep 2024 19:52:13 +0000 In conversation with Martin Griffiths: How can a divided world address conflict? 1 October 2024 — 10:00AM TO 11:00AM Anonymous (not verified) 16 September 2024 Chatham House and Online The former United Nations Under-Secretary-General describes how a weakening multilateralism system and dysfunctional political diplomacy can be revitalized by a humanitarian approach. The international community is failing to stop conflict. Despite efforts by international organisations and state actors to resolve or prevent it from breaking out, wars around the world have left millions of people suffering. Unstable governments and global insecurity are contributing to an age of poly-crisis, compounded by growing inequity and impunity.How can a divided world work better to prevent and resolve conflict and reduce the suffering of the civilians affected?Martin Griffiths has spent decades working within the United Nations system and other institutions on conflict resolution and humanitarian action, most recently as Under-Secretary General for Humanitarian Affairs and the Emergency Relief Coordinator. He worked on peace deals in Indonesia, Spain, Thailand, Myanmar, Darfur, Syria and Yemen and responded to emergencies in Ethiopia, Haiti, Afghanistan, Syria, Ukraine, Sudan, Turkiye and Gaza and elsewhere. In this discussion, he casts his expertise over the biggest challenges in the world today and assess the prospects for international cooperation on conflict resolution in the future.Key questions to be discussed include:How can a lasting peace be secured in the conflict between Israel and Palestine ?Is the world too fragmented to prevent or resolve conflicts around the world?What role can the United Nations play in today’s geopolitical environment?How can the West and Global South better engage to limit conflict ?Individual membership provides you with the complete Chatham House experience, connecting you with a unique global policy community. Find out more about membership. Full Article
wit In conversation with Speaker Emerita Nancy Pelosi By www.chathamhouse.org Published On :: Thu, 19 Sep 2024 10:52:13 +0000 In conversation with Speaker Emerita Nancy Pelosi 14 October 2024 — 12:00PM TO 1:00PM Anonymous (not verified) 19 September 2024 Chatham House and Online The former Speaker of the House of Representatives discusses challenges to American democracy and the importance of leadership in an election year. As the US gears up for the 2024 Presidential election, the importance of leadership in politics has come to the fore. As the Harris and Trump campaigns move towards election day, the heightened sense of strong leadership is central to the position of both candidates.Following her first election to the House in 1987, Speaker Emerita Nancy Pelosi has been central to American political leadership for over two decades. Serving as the 52nd Speaker of the House of Representative, Speaker Pelosi rose to become one of the most powerful and consequential Speakers in American political history.Following the release of her recent book The Art of Power, Speaker Pelosi will discuss how she became a master legislator, working with numerous presidents, her political legacy in the house and her leadership during a contentious time in US politics. Full Article
wit Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography [Enzymology] By www.jbc.org Published On :: 2020-12-11T00:06:21-08:00 The main protease (3CL Mpro) from SARS–CoV-2, the etiological agent of COVID-19, is an essential enzyme for viral replication. 3CL Mpro possesses an unusual catalytic dyad composed of Cys145 and His41 residues. A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active-site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus. Here, we present the room-temperature neutron structure of 3CL Mpro, which allowed direct determination of hydrogen atom positions and, hence, protonation states in the protease. We observe that the catalytic site natively adopts a zwitterionic reactive form in which Cys145 is in the negatively charged thiolate state and His41 is doubly protonated and positively charged, instead of the neutral unreactive state usually envisaged. The neutron structure also identified the protonation states, and thus electrical charges, of all other amino acid residues and revealed intricate hydrogen-bonding networks in the active-site cavity and at the dimer interface. The fine atomic details present in this structure were made possible by the unique scattering properties of the neutron, which is an ideal probe for locating hydrogen positions and experimentally determining protonation states at near-physiological temperature. Our observations provide critical information for structure-assisted and computational drug design, allowing precise tailoring of inhibitors to the enzyme's electrostatic environment. Full Article
wit China's Evolving Economic Relations with North Africa: Before and After COVID-19 By www.chathamhouse.org Published On :: Thu, 20 Aug 2020 14:30:01 +0000 China's Evolving Economic Relations with North Africa: Before and After COVID-19 10 September 2020 — 12:00PM TO 1:30PM Anonymous (not verified) 20 August 2020 Online China’s economic presence across North Africa has grown in recent years. The global power has forged close economic relationships with Egypt and Algeria, while also continuing to develop ties with Morocco and Tunisia. Beijing, which views the region as a geostrategic intersection between Mediterranean, Middle East, and Africa, has primarily focused its efforts on developing bilateral relations, while also working within the Forum on China–Africa Cooperation (FOCAC) and the China–Arab States Cooperation Forum (CASCF). All countries of the region have agreed to participate in China’s Belt and Road initiative (BRI), which has raised concerns among Western powers. As North African countries grapple with fiscal constraints as part of the fallout from COVID-19 (and the oil price drop for hydrocarbon exporters such as Algeria), it is yet to be seen whether China’s ambitions and relations within the region will continue to develop at the same pace going forward. In this webinar, organized by Chatham House’s MENA and Asia-Pacific Programmes, experts will discuss the evolving economic relationship between China and North African states, and explore the impact of China’s pandemic diplomacy across the region. How asymmetric are economic relations between China and North African states? Which sectors are most important, and what are the prospects for China to develop the region’s digital and healthcare infrastructure? Will China’s increasing economic interests necessitate an increasing political and security engagement? Should North African states be wary of Chinese loans? What is the public opinion of China’s economic presence in North Africa? Have Chinese ‘soft power’ efforts helped to bolster economic (and political) ties? What will be the likely fallout of COVID-19 on BRI and infrastructure projects in the region? You can express your interest in attending by following this link. You will receive a Zoom confirmation email should your registration be successful. Alternatively, you can watch the event live on the MENA Programme Facebook page. Full Article
wit In conversation with Ursula Burns By www.chathamhouse.org Published On :: Thu, 15 Sep 2022 11:07:14 +0000 In conversation with Ursula Burns 27 September 2022 — 1:00PM TO 2:00PM Anonymous (not verified) 15 September 2022 Chatham House and Online Ursula Burns and Fred P. Hochberg share insights on American business and corporate life. In the next of our conversations with CEOs, Ursula Burns, former CEO of the Xerox corporation, joins Fred P. Hochberg, former chairman of the Export-Import Bank of the United States, to share her insights on American business and corporate life. Drawing from her recent book, Where You Are is not Who You Are, Burns will offer her reflections on the challenges leadership faces in a corporate world with rapidly changing technology and creating a diverse work environment. Hochberg and Burns will also discuss her views on racial and economic justice, as well as prospects for future business and economic growth. Full Article
wit Ethics of dealing with authoritarians By www.chathamhouse.org Published On :: Mon, 20 Mar 2023 16:32:13 +0000 Ethics of dealing with authoritarians 28 March 2023 — 12:00PM TO 1:00PM Anonymous (not verified) 20 March 2023 Chatham House How can democracies simultaneously defend human rights and promote open societies while still engaging with leaders from non-democratic states as strategic allies? In 2022, the Biden administration called upon the world’s democracies to unite against a rising tide of autocracy. Through its messaging, conferences, and op-eds, the US and its allies presented the public with a binary choice: democracy or autocracy. But in today’s world, and in the practice of international relations, the choice is rarely this simple. Joel Rosenthal, president of Carnegie Council, joins Chatham House to discuss how democracies and multilateral institutions can leverage ethics as a tool to assess concerns and trade-offs when engaging with illiberal actors. Can democracies afford to be adversarial with certain countries or overly selective in cooperation when facing global-scale challenges such as climate change and the emergence of AI? How can democracies simultaneously defend human rights and promote open societies while still engaging with leaders from non-democratic states as strategic allies? Full Article
wit A "Proteomic Ruler" for Protein Copy Number and Concentration Estimation without Spike-in Standards By www.mcponline.org Published On :: 2014-12-01 Jacek R. WiśniewskiDec 1, 2014; 13:3497-3506Research Full Article
wit Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues By www.mcponline.org Published On :: 2015-05-01 Roland BrudererMay 1, 2015; 14:1400-1410Research Full Article
wit A Tandem Affinity Tag for Two-step Purification under Fully Denaturing Conditions: Application in Ubiquitin Profiling and Protein Complex Identification Combined with in vivoCross-Linking By www.mcponline.org Published On :: 2006-04-01 Christian TagwerkerApr 1, 2006; 5:737-748Research Full Article