Analyst, 2024, 149,5353-5359
DOI: 10.1039/D4AN00975D, Paper

Yang Yang, Rui Jiang, En-lai Yang, Jiahao Liang, Ying Xu, Xu-dong Wang
Highly sensitive and reversible fluorescence H₂O₂ sensor with a limit of detection of 0.02 ppm had been developed. The sensor responded rather fast, had high stability, and can be massively produced with good batch-to-batch consistency.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00983E, Paper

Kwanhwi Ko, Hajun Yoo, Sangheon Han, Won Seok Chang, Donghyun Kim
The combination of dielectrophoresis and surface-enhanced Raman spectroscopy provides an effective method for analyzing the Raman characteristics and the dielectrophoretic behavior of polystyrene beads and U-87MG cells in a microfluidic environment.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01160K, Paper

Maria Nikitina, Pavel Khramtsov, Stepan Devyatov, Rishat Valeev, Marina Eryomina, Andrey Chukavin, Mikhail Rayev
LaNiO₃ nanosphere-based NLISA has been demonstrated for the first time. The assay enables the CRP effective detection with high sensitivity.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00964A, Paper

Feng-yan Kuang, De-jun Hu, Lu Wang, Fei Chen, Guang-ping Lv
The selection of the matrix is crucial for matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI).
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01005A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Oksana A. Bondar, Gamal A. I. Moustafa, Thomas B. R. Robertson
The NMR hyperpolarisation technique SABRE has been used to hyperpolarise ¹³C labelled pyruvate in a predominantly aqueous solution which has then been measured by benchtop NMR.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01082E, Critical Review

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Jagpreet Singh Sidhu, Gurjot Kaur, Atharva Rajesh Chavan, Mandeep Chahal, Rajeev Taliyan
The use of chemiluminophores for tracing enzymatic activities in live-cell imaging has gained significant attention, making them valuable tools for diagnostic applications. Among various chemiluminophores, the phenoxy-1,2-dioxetane scaffold exhibits significant...
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Analyst, 2024, 149,5372-5380
DOI: 10.1039/D4AN00861H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Felix Frank, Daniela Tomasetig, Peter Nahringbauer, Wolfgang Ipsmiller, Gerd Mauschitz, Karin Wieland, Bernhard Lendl
Coupling Raman and VIS spectroscopy enables the study of AgNP aggregations induced by surfactants.
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Analyst, 2024, 149,5443-5454
DOI: 10.1039/D4AN00956H, Paper

Patrycja Leszczenko, Anna M. Nowakowska, Patrycja Dawiec, Karolina Czuja, Justyna Jakubowska, Marta Zabczynska, Agata Pastorczak, Kinga Ostrowska, Szymon Tott, Wojciech Mlynarski, Malgorzata Baranska, Katarzyna Majzner
Acute lymphoblastic leukaemia (ALL) is a complex disease in pediatric oncology, necessitating accurate diagnostic strategies for effective treatment planning.
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Analyst, 2024, 149,5381-5393
DOI: 10.1039/D4AN00868E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Edoardo Farnesi, Matteo Calvarese, Chen Liu, Carl Messerschmidt, MohammadSadegh Vafaeinezhad, Tobias Meyer-Zedler, Dana Cialla-May, Christoph Krafft, Jonas Ballmaier, Orlando Guntinas-Lichius, Michael Schmitt, Jürgen Popp
The study demonstrates the potential of advanced vibrational spectroscopy to reveal the complex molecular composition of cerumen, suggesting its promising application as a non-invasive diagnostic tool for identifying disease-related biomarkers.
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Analyst, 2024, 149,5401-5410
DOI: 10.1039/D4AN00990H, Paper

Nor Dyana Zakaria, Ibrahim Luqman Salih, Hairul Hisham Hamzah, Turgut Sönmez, Muhamad Huzaifah Omar, Noorhashimah Mohamad Nor, Khairunisak Abdul Razak, Venugopal Balakrishnan
The graphic abstract displays the integration of the SPGE measurement system with an electrochemical cell-based 3D printing to evaluate the electrochemical behaviors and 3D images of both unactivated and activated SPGEs.
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Analyst, 2024, 149,5482-5490
DOI: 10.1039/D4AN01186D, Paper

Jin Wang, Xiangmei Li, Hongtao Lei, Juewen Liu
Using capture-SELEX, short aptamers for metronidazole and ibuprofen were isolated and they can be used for the detection of these drugs illicitly added to soft drinks.
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Analyst, 2024, 149,5411-5422
DOI: 10.1039/D4AN01136H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Mohammad Hossein Ghanbari, Markus Biesalski, Oliver Friedrich, Bastian J. M. Etzold
Screen printing was employed for the first time to examine the effect of electrode size and arrangement on the performance of a microfluidic paper-based electroanalytical device for clozapine sensing.
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Analyst, 2024, 149,5394-5400
DOI: 10.1039/D4AN01060D, Paper

Xiaoqing Zhang, Shanglin Li, Mei Liu
A fluorescence biosensing strategy was developed based on CuS-BSA for sensitive and rapid detection of Escherichia coli.
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Analyst, 2024, 149,5527-5534
DOI: 10.1039/D4AN01107D, Paper

Hongliang Ma, Shiqi Wang, Gaoxuan Wang, Qilei Zhang, Shenlong Zha, Xueyuan Cai, Lingli Li, Pan Pan, Qiang Liu, Shengbao Zhan
A novel method combining dual-channel concentration signal averaging with detector gain optimization is proposed to improve the measurement precision and response speed of the sensor within the 1–10 second integration time.
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Analyst, 2024, 149,5555-5562
DOI: 10.1039/D4AN01075B, Paper

Nikita Thomas, Mengzhen Lyu, Jadon Khouv, Dhésmon Lima, Sabine Kuss
The cellular electrochemical current response is impacted by media composition and light exposure during scanning electrochemical microscopy (SECM).
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Analyst, 2024, 149,5463-5475
DOI: 10.1039/D4AN01044B, Paper

Zuriel Erikson Joven, Piyush Raj, Ishan Barman
Monte Carlo simulations of spatially offset Raman spectroscopy (SORS) produce widely-applicable, quantitative frameworks for optimizing and interpreting SORS experiments.
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Analyst, 2024, 149,5433-5442
DOI: 10.1039/D4AN00787E, Paper

Qi Wang, Pei Liu, Ke Xiao, Wenying Zhou, Jinfeng Li, Yun Xi
Group A streptococcus (GAS) is a pathogen typically transmitted through respiratory droplets and skin contact, causing an estimated 700 million mild non-invasive infections worldwide each year.
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Analyst, 2024, 149,5491-5503
DOI: 10.1039/D4AN00866A, Paper

Vandana Kuttappan Nair, Chandrika Sharma, Shrawan Kumar, Mrittika Sengupta, Souradyuti Ghosh
Comprehensive quantitative analysis of various ligation and digestion conditions to identify and minimize non-specific amplification in RCA bioanalytical methods.
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Analyst, 2024, 149,5476-5481
DOI: 10.1039/D4AN00758A, Paper

Erli Cai, Yage Chen, Jing Zhang, Haozheng Li, Yiran Li, Shuai Yan, Zhiyong He, Quan Yuan, Ping Wang
For living HeLa cells, we report a small and minimally-invasive Raman reporter (about 2 aa and <1 kDa), which can be site-specifically introduced into proteins by genetic codon expansion combined with tetrazine ligation.
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Analyst, 2024, 149,5563-5571
DOI: 10.1039/D4AN01127A, Paper

Zhentao Sun, Youquan Zhao, Yameng Liu, Chen Chen, Hao Chen
A paper-based microfluidic disc is used for the rapid determination of various nutrients in water.
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Analyst, 2024, 149,5518-5526
DOI: 10.1039/D4AN01139B, Paper

Tapparath Leelasattarathkul, Thithawat Trakoolwilaiwan, Kawin Khachornsakkul
A simple and low-cost distance-based paper analytical device (dPAD) was combined with gold nanomaterials for uric acid quantification.
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Analyst, 2024, 149,5546-5554
DOI: 10.1039/D4AN01096E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ruchi Gupta, Nicholas J. Goddard
In this work, acoustically levitated droplets serve as wells of microtitre plates and are acoustically manipulated to perform chemical and biological reactions in a non-contact fashion.
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Analyst, 2024, 149,5535-5545
DOI: 10.1039/D4AN00729H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Katherine J. I. Ember, Nassim Ksantini, Frédérick Dallaire, Guillaume Sheehy, Trang Tran, Mathieu Dehaes, Madeleine Durand, Dominique Trudel, Frédéric Leblond
Raman spectroscopy and machine learning is used in combination to detect COVID-19 positive saliva in liquid form.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00784K, Paper

Liang Ma, Wenqing Gao, Xiangyang Hu, Dongdong Zhou, Chenlu Wang, Jiancheng Yu, Keqi Tang
An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and 1D neural network combining ResNet and SENet is proposed and successfully applied to the diagnosis of ovarian cancer with high accuracy and strong fitting ability.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01244E, Paper

Léa Habib, Rime Michael-Jubeli, Marie Abboud, Roger Lteif, Ali Tfayli
Blue light alters lipids and proteins in the reconstructed human epidermis.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01112K, Paper

Johan Yi, Suyeon Kim, Chungmin Han, Jaesung Park
A TIRF microscopy-based method for single vesicle aggregation analysis enables precise assessment of EV aggregation under various conditions, enhancing EV characterization and functional analysis.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01175A, Minireview

Chenyang Xu, Huanhuan Shi, Zhongjian Tan, Yun Zheng, Weizheng Xu, Zhengxian Dan, Jiacong Liao, Zhiying Dai, Yali Zhao
This review discusses the formation and manipulation of magnetic droplets on microfluidic chips and classifies related detection techniques. Applications in biomedicine were reviewed. Future development of this emerging field is provided.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00872C, Paper

Chia Yen Liew, Wun-Long Li, Chi-Kung Ni
Logical procedures for structural determination of fructooligosaccharides and raffinose family oligosaccharides.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01269K, Paper

Hong Zeng, Xiao Ma, Shufen Pan, Yuting Han, Yanyan Tang, Yulan Fan, Yongquan Wu
Inflammation is a complex physiological response involving various cellular and molecular events. Sulfur dioxide (SO2), which is usually in the form of HSO3- and SO32- under physiological conditions, plays a...
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01164C, Paper

Anil Sharma, Thomas Hulse, Aymen H. Qatamin, Monica Moreno, Klester S. Souza, Marcelo B. Pereira, Fabricio S. Campos, Leandro B. Carneiro, Antonio M. H. de Andrade, Paulo M. Roehe, Flavio Horowitz, Sergio B. Mendes
This article focuses on the application of electrochemically modulated surface plasmon waves for structural characterization and for assessing signal transduction performance of redox-labeled DNA-based sensing platforms.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01029A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Md Raduanul H. Chowdhury, Clementinah Oladun, Nuwandi M. Ariyasingha, Anna Samoilenko, Tarek Bawardi, Dudari B. Burueva, Oleg G. Salnikov, Larisa M. Kovtunova, Valerii I. Bukhtiyarov, Zhongjie Shi, Kehuan Luo, Sidhartha Tan, Juri G. Gelovani, Igor V. Koptyug, Boyd M. Goodson, Eduard Y. Chekmenev
The feasibility of ultrafast (1.7 s) ventilation MRI with a 1 × 1 × 50 mm³ voxel size is demonstrated using hyperpolarized propane gas contrast agent in excised rabbit lungs on a 0.35 T clinical MRI scanner without any scanner modification.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01054J, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Eirini Malegiannaki, Pascal Bohleber, Daniele Zannoni, Ciprian Stremtan, Agnese Petteni, Barbara Stenni, Carlo Barbante, Bo M. Vinther, Vasileios Gkinis
A new micro-destructive technique for high-resolution water isotope analysis of ice samples using a Laser Ablation (LA) system coupled with a Cavity Ring Down Spectrometer (CRDS) is presented.
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Phys. Chem. Chem. Phys., 2024, 26,27325-27331
DOI: 10.1039/D4CP00954A, Paper

Feijun Huang, Wenli Su, Yubo Yang, Hang Wang, Zhishan Bo, Pengfei Jing, Wenkai Zhang
The Se-modified PDI oligomers experience triplet states formation in the solvents, but there are differences in the efficiency of triplet state generation due to variations in molecular structure.
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Phys. Chem. Chem. Phys., 2024, 26,27447-27458
DOI: 10.1039/D4CP02551B, Paper

Alessandro Bonardi, Michele Turelli, Giorgio Moro, Claudio Greco, Ugo Cosentino, Carlo Adamo
Among all the possible candidates involved in the NanoLuc bioluminiescnce, this computational analysis identifies the enol tautomer of furimazine as a probable reactive species and the zwitterionic forms of furimamide as the luminescent product.
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Phys. Chem. Chem. Phys., 2024, 26,27363-27370
DOI: 10.1039/D4CP03470H, Paper

Rouhollah Farghadan
This study explores how bending and gate voltage tune the spintronic properties of zigzag phosphorene nanoribbons (ZPNRs) for advanced applications.
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Phys. Chem. Chem. Phys., 2024, 26,27348-27362
DOI: 10.1039/D4CP02431A, Paper

Millena Logrado, Yara Hellen Firmo Gomes, Tomiki Inoue, Shingo Nakane, Yoshinari Kato, Hiroki Yamazaki, Akihiro Yamada, Hellmut Eckert
Superposition of ¹⁷O triple-quantum magic-angle spinning NMR spectra of 20MgO–20Al₂O₃–60SiO₂ (MAS**) and 20Na₂O–20Al₂O₃–60SiO₂ (NAS**) glasses prepared at ambient pressure (AP) and pressurized and decompressed at 25 GPa at room temperature (HP(25)).
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Phys. Chem. Chem. Phys., 2024, 26,27301-27313
DOI: 10.1039/D4CP03217A, Paper

Valentina V. Sobornova, Valeriya V. Mulloyarova, Konstantin V. Belov, Alexey A. Dyshin, Peter M. Tolstoy, Mikhail G. Kiselev, Ilya A. Khodov
The structural and sorption characteristics of a composite material consisting of a silica aerogel loaded with flufenamic acid were investigated using a variety of nuclear magnetic resonance techniques.
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Phys. Chem. Chem. Phys., 2024, 26,27648-27659
DOI: 10.1039/D4CP01811G, Paper

Lokesh Soni, Raj Kumar, Kamendra P. Sharma, Ajay Singh Panwar
Dispersion of protein–polymer surfactant bioconjugates was stabilised by a combination of surface overcharging and steric exclusion of long chain cations in neat aprotic ionic liquid.
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Phys. Chem. Chem. Phys., 2024, 26,27382-27394
DOI: 10.1039/D4CP03716B, Paper

Steve Scheiner
All metals of the d-block are capable of forming σ and π-hole bonds to a nucleophile. Some of these bonds are typical of noncovalent bonds, but others are strong enough to be characterized as a covalent coordinate bond.
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Phys. Chem. Chem. Phys., 2024, 26,27431-27438
DOI: 10.1039/D4CP02889A, Paper

Open Access

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Usman Ahmed, Dage Sundholm, Mikael P. Johansson
Calculations on molecules with self-complementary hydrogen bonding show that hydrogen bonds increase the energy of π–π stacking interactions.
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