The Decision-Recommendation on the Co-operative Investigation and Risk Reduction of Chemicals revises and replaces a 1991 Decision-Recommendation of the Council. The Decision-Recommendation is composed of two parts: Part A focuses on the development of harmonised hazard and exposure assessment methodologies for chemicals and Part B focuses on risk prevention and reduction.

The OECD Conference on Genome Editing: Applications in Agriculture – Implications for Health, Environment and Regulation will explore the regulatory considerations raised by genome edited products, with the aim to favour a coherent policy approach to facilitate innovation involving genome editing. More information on the programme and the speakers.

This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines.

This paper reviews and compares five case studies on quantification and economic valuation of benefits in cost-benefit analyses (CBAs) of regulating phthalates, mercury, PFOA (perfluoro-octanic acid) and its salts, NMP (1 methyl-2-pyrroloidine) and formaldehyde. The case studies had all been carried out as part of the SACAME project, and the purpose of the present paper is to draw out cross-cutting findings from these studies.

The Product Release and Exposure Data Warehouse is a Microsoft® Access 2016 database is designed to house existing data on releases of chemicals from, and exposures to, commercial and consumer end products. A number of forms provide a simple approach to data entry and access to the existing data.

This document outlines various approaches and methodologies for the assessment of risks from combined exposures to multiple chemicals. The document draws from approaches and experience in the regulatory context, and presents elements to consider in the assessment.

The OECD releases a video tutorial on how to find GHS information in eChemPortal through the substance search and how to search by GHS classification. Currently 11 databases provide GHS information, independent of whether the classifications have undergone a review by a regulatory body or intergovernmental organisation or are based on self-classifications by the producers or importers.

Today, OECD Council adopted the Recommendation on Countering the Illegal Trade of Pesticides to strengthen cooperation between countries and inspectors and identify illegal pesticides throughout their lifecycle with a Best Practice Guidance.

This report outlines the customisation opportunities for IUCLID version 6. It also gives an overview of what IUCLID offers to regulatory bodies and industry as a key application to record, store, maintain and exchange data on chemicals. IUCLID is used in a variety of countries and regulatory contexts, therefore the report describes to which extent it is customisable to facilitate the management of chemical data across these contexts.

Nanomaterials have unique physical and chemical features. OECD's Decision Framework and Guiding Principles tools fill data gaps in the hazard characterisation by identifying the most useful parameters and best available methods for a given type of nanomaterial.

The purpose of this document is to give guidance to Receiving Authorities on the evaluation of the GLP compliance status of nonclinical safety studies submitted for regulatory purposes. This guidance does not address the scientific evaluation and interpretation of the submitted data or the risk assessment based on these data.

Latest releases: AOPs are the central element of a toxicological knowledge framework, promoted by member countries through OECD, built to support chemical risk assessment based on mechanistic reasoning. Seven New AOPs have now been published.

Two new cases have been published that focus on use of metabolism information to support read-across and use of a combination of novel methods to identify potential endocrine disruptors, respectively. In addition a considerations document includes lessons and learnings from analysis across case studies and an analysis of uncertainties in six read-across cases.

On Thursday 26 September 2019, the OECD discussed "Finding Alternatives to Per- and Polyfluoroalkyl Substances of Concern: A Difficult and Continuing Challenge" with the participation of W.L. Gore & Associates, Inc. Presenters shared efforts, successes and challenges in eliminating per and polyfluorinated chemicals of environmental concern from the life cycle of consumer products.

A major fruit crop of temperate regions, APPLE is consumed worldwide as fresh fruit, juice and other food products. This consensus document provides science-based key insights for the regulatory assessment of the environmental safety of genetically-engineered products: taxonomy, reproductive biology, genetics, hybridisation and introgression, and ecology.

This document is intended to provide universal Guiding Principles that should be considered when developing or augmenting systematic approaches to Weight of Evidence (WoE) for chemical evaluation and Key Elements to formulating a systematic approach to WoE. The ultimate goal is to facilitate that regulators follow a consistent, clear and transparent delivery of evidence using the Principles and Elements described in this document.

Standard & Poor's credit rating for the United States stands at AA+ with stable outlook. Moody's credit rating for the United States was last set at Aaa with stable outlook. Fitch's credit rating for the United States was last reported at AAA with stable outlook. DBRS's credit rating for the United States is AAA with stable outlook. In general, a credit rating is used by sovereign wealth funds, pension funds and other investors to gauge the credit worthiness of the United States thus having a big impact on the country's borrowing costs. This page includes the government debt credit rating for the United States as reported by major credit rating agencies.

United States recorded 1347318 Coronavirus Cases since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 78616 Coronavirus Deaths. This page includes a chart with historical data for the United States Coronavirus Cases.

United States recorded 80040 Coronavirus Deaths since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 1347318 Coronavirus Cases. This page includes a chart with historical data for the United States Coronavirus Deaths.

United States recorded 238080 Coronavirus Recovered since the epidemic began, according to the World Health Organization (WHO). In addition, United States reported 80040 Coronavirus Deaths. This page includes a chart with historical data for the United States Coronavirus Recovered.

Standard & Poor's credit rating for Turkey stands at B+ with stable outlook. Moody's credit rating for Turkey was last set at B1 with negative outlook. Fitch's credit rating for Turkey was last reported at BB- with stable outlook. DBRS's credit rating for Turkey is BB (high) with negative outlook. In general, a credit rating is used by sovereign wealth funds, pension funds and other investors to gauge the credit worthiness of Turkey thus having a big impact on the country's borrowing costs. This page includes the government debt credit rating for Turkey as reported by major credit rating agencies.

The ATX decreased 983 points or 30.44% since the beginning of 2020, according to trading on a contract for difference (CFD) that tracks this benchmark index from Austria. Historically, the Austria Stock Market (ATX) reached an all time high of 5010.93 in July of 2007. The Vienna Stock Exchange Index is a major stock market index which tracks the performance of all companies listed in Austria. It is a market capitalisation weighted price index. The WBI represents around 60% of Austrian stock trade. The index has a base value of EUR100 as of December 31, 1967.

Have we gone from protecting nature to managing it on behalf of the Earth’s dominant species?

The story of Sisyphus compares quite well with the experience of zero-hours contracts

Caricaturist James Gillray was arrested over a print showing politicians kissing a new royal baby’s backside

Perhaps a lot of rugby has always been prosaic but I struggle to recall such a dearth of poetry

An imaginative journey into the life and work of an elusive Roman poet

Elected rulers use heavy-handed authority to prevent being toppled by swings in opinion

Whatever his short-term plans, Trump wants a radical tightening of US border policy

Americans resent inquisitions aimed at depriving them of their elected president

With new owners, falling viewers and spiralling costs, Formula One is at a crossroads

After a stormy summer, the chief is shaking up the world’s biggest shipping company

After weathering the country’s worst recession, Candido Bracher is looking to expand

The Japanese trading house trusts its history of investment to create new lines of business

In a male-dominated industry, the executive says she has not been held back

Your boss and possibly you have a completely outdated view of the Thai capital and need to give it a fresh look

I can’t help but question if airlines wouldn’t be further ahead if they had just stuck to getting the basics right

Young Canadians should do like Aussies and Kiwis by getting out into the world for extended periods

The facts are very simple: automatic weapons have no place in civil society, even when licensed

Is Bombardier C Series the plane business travellers have been waiting for?

My desk and I are having issues. I’m away so often, it’s decided to lead a life of its own

US 52 Week Bill Bond Yield was 0.15 percent on Friday May 8, according to over-the-counter interbank yield quotes for this government bond maturity. Historically, the United States 52 Week Bill Yield reached an all time high of 17.31 in September of 1981.

US 1 Month Bill Bond Yield was 0.10 percent on Friday May 8, according to over-the-counter interbank yield quotes for this government bond maturity. Historically, the United States 4 Week Bill Yield reached an all time high of 5.17 in November of 2006.

US 3 Year Note Bond Yield was 0.21 percent on Friday May 8, according to over-the-counter interbank yield quotes for this government bond maturity. Historically, the United States 3 Year Note Yield reached an all time high of 9.11 in May of 1990.

US 2 Year Note Bond Yield was 0.15 percent on Friday May 8, according to over-the-counter interbank yield quotes for this government bond maturity. Historically, the United States 2 Year Note Yield reached an all time high of 16.95 in September of 1981.

For investors tempted to put money into the stock market, there are some basic rules to consider

Economy minister says comprehensive inspection is part of measures needed to save economy

The emirate’s economy is especially vulnerable, and may need a bailout from its big brother, Abu Dhabi