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Drawings from India




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Drawings from India




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Ringing in their independence

On this day in 1776, the Liberty Bell rang out from the tower of the Pennsylvania State House.




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Drawings from India




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Drawings from India




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Drawings from India




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Drawings from India




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Drawings from India




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25YT_DRAWINGS FROM INDIA part I




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25YT_DRAWINGS FROM INDIA part II




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Drawings from India




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Drawings from India




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Drawings from India




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Drawings from India




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Drawings from India I




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Drawings from India II




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Drawings from India III




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Drawings from India IV




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A water mediated multicomponent reaction for the synthesis of novel spirooxindole derivatives and their antifungal activity

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00256C, Paper
Min Zhang, Liang Shi, Li Chen, Zhengyu Liu, Ting Zhao, Chunyin Zhu, Liuqing Yang
A total of 27 novel spirooxindoles were synthesized through a water mediated three-component reaction of isatin, 4-aminocoumarin, and 1,3-cyclodicarbonyl compounds. Several compounds showed excellent antifungal activity against Physalospora piricola.
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Dehydrative alkynylation of 3-hydroxyisoindolinones with terminal alkynes for the synthesis of 3-alkynylated 3,3-disubstituted isoindolinones

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00190G, Paper
Kai-Cheng Yang, Shi-Lu Zheng, Zhong Wen, Yu-Shan Zhang, Hai-Liang Ni, Long Chen
A HOTf or Fe(OTf)3-catalyzed dehydrative alkynylation of 3-hydroxyisoindolinones with terminal alkynes was developed, which represents a brand-new procedure for the synthesis of 3-alkynylated 3,3-disubstituted isoindolinones.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Diastereoselective synthesis of functionalized spiroindolines via intramolecular ipso-iodocyclization/nucleophile addition cascade reactions of indole-tethered ynones

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00112E, Paper
Debojyoti Bag, Sanghapal D. Sawant
Herein, we describe a highly diastereoselective approach for synthesizing polyfunctionalized spiroindolines from indolyl-ynones involving an ipso-iodocyclization/nucleophile addition cascade.
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Photoinduced decatungstate-catalyzed C(sp3)–H thioetherification by sulfinate salts

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00394B, Paper
Pengcheng Li, Jia-Lin Tu, Ao-Men Hu, Lin Guo, Chao Yang, Wujiong Xia
A visible light photoinduced decatungstate-catalyzed C(sp3)–H thioetherification of hydrocarbons by sodium sulfite is herein reported.
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HFIP-mediated C-3-alkylation of indoles and synthesis of indolo[2,3-b]quinolines & related natural products

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00414K, Paper
Auqib Rashid, Waseem I. Lone, Preeti Dogra, Showkat Rashid, Bilal A. Bhat
An expeditious metal free C-3 alkylation of indoles and its NIS-mediated deviation to indolo[2,3-b]quinolines is reported. Applications of these strategies in accessing bioactive natural products have also been demonstrated.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Iron-catalyzed selective construction of indole derivatives via oxidative C(sp3)–H functionalization of indolin-2-ones

Org. Biomol. Chem., 2024, 22,3073-3079
DOI: 10.1039/D4OB00133H, Paper
Wei Chen, Lang-Qi Wen, Xiao-Bing Lu, Hui Zhou
We have developed a clean and efficient iron-catalyzed C(sp3)–H functionalization of indolin-2-ones for the chemodivergent synthesis of value-added indole derivatives, including isatins, and symmetrical and non-symmetrical isoindigos.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cu(OTf)2/HFIP catalyzed regioselective cycloisomerization of indole-C3-functionalized alkynols to carbazoles

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00421C, Communication
Srinivasarao Yaragorla, Tabassum Khan, Sayonika Chakroborty
We report here a simple and atom economic cycloisomerization reaction of indole-tethered alkynols for constructing diverse carbazoles via 1,2-alkly migration using Cu(OTf)2/HFIP as the excellent promoter system.
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Tetrabutylammonium decatungstate (TBADT), a compelling and trailblazing catalyst for visible-light-induced organic photocatalysis

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00171K, Review Article
Bor-Cherng Hong, Ranadheer Reddy Indurmuddam
This review summarizes recent developments in visible-light or near-visible-light photocatalysis reactions enabled by the TBADT catalyst.
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K2CO3-Mediated (3+3-1) Annulation of 1,3-Acetonedicarboxylates with 2-Fluoro-1-nitroarenes: Synthesis of Indoles

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00488D, Paper
Meng-Yang Chang, Chin-Huey Ho, Hsing-Yin Chen
The K2CO3-mediated one-pot reaction of 1,3-acetonedicarboxylates with 2 equiv. of substituted 2-fluoro-1-nitrobenzenes has been developed to synthesize various 2,3-dicarboxylate indoles via a tandem (3 + 3 − 1) annulation pathway....
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Indian aviation: A study in paradox

Accurate reading of the market is critical




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Air India sale: Who will bag the Maharaja's crown?

Financial bid winner for sale of the State-owned airlines to be declared in three weeks; sources say it may take longer




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India ahead in tech to make airports safer

Airports are also keeping pace to ensure safe, touchless and seamless journeys




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Lost your baggage in transit? You might find it in Alabama

Every year, nearly 25 million bags are lost in transit out of 4.3 billion 




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As India builds its newest airports, it needs robust, fail-proof SOPs

A near air mishap on Bengaluru skies that put the lives of 430 people in danger shows safety risk norms require constant refresh




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Aviation industry shifts focus to digital

The pandemic has helped usher in automated touchpoints for tech-savvy flight passengers




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Domestic airline industry may face a rejig

The pandemic laid bare fault-lines within India’s airlines




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Redressing flaws: IndiGo needs to tweak its way

How the human element can help the airline appease passengers and employees




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Slots scarcity hits Indian airlines’ flight roadmap

The solution demands a comprehensive expansion of airside capacity across the country, but that has not materialised




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5 things Indian airlines must do to break their way out of pandemic blues

Post pandemic, the airlines must revamp strategies and resort to long-term measures to recover from the crisis 




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Why do planes leave a white trail behind them?




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Air India’s roadmap can be tricky to pull off

The airline has to work hard to drastically grow its network and fleet while improving reliability as well




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Why has private capital not been taken to Indian aviation 

With banks becoming increasingly cautious and credit flows tightening, private capital must be explored and enticed




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Youtube introduces shopping affiliate programme for eligible Indian creators via Flipkart and Myntra

As more platforms allow creators to earn from viewers’ purchases of featured products, YouTube also announced its Shopping affiliate programme in India




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Sarvam AI launches Sarvam 1 for Indic languages

The custom training corpus, Sarvam-2T comprised of 20 percent datasets in Hindi as well as English and programming languages so the AI model can perform multilingual tasks




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Crypto firm Consensys to cut 20% of workforce amid macroeconomic, regulatory headwinds

The crypto firm added that elevated interest rates, inflationary pressures, and tightening liquidity have created a more “cautious macroeconomic environment”




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Indonesia bans sales of Google phones days after blocking Apple's iPhone 16

Indonesia said it has banned sales of smartphones made by Alphabet's Google due to rules requiring the use of locally manufactured components




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Sexual harassment rampant in Maharashtra medical colleges, finds survey

The survey also found that a majority of students believed that reporting these events could negatively affect their grades and future prospects; it highlighted the need for better safety mechanisms on campus




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Acute Flaccid Paralysis surveillance as a crucial defence against polio in India | Explained

India needs to continue efforts to maintain its polio-free status, and AFP surveillance has to remain a cornerstone of its strategy




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Over 77 per cent of India’s children lack WHO-suggested diversity in diet, study finds

The states of Uttar Pradesh, Rajasthan, Gujarat, Maharashtra and Madhya Pradesh reported the highest levels of inadequate diversity in children's diets -- all above 80 per cent -- while Sikkim and Meghalaya were the only two to report an under-50 per cent prevalence




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Trachoma eliminated as a public health problem in India; what next?

The achievement marks a significant public health victory and has profound economic implications. Trachoma’s impact, through blindness and visual impairment, results in an estimated economic loss of $2.9 to 5.3 billion annually due to reduced productivity




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Drugs regulator finds 49 samples not of standard quality, manufacturers asked to withdraw their products

Four spurious drugs were also found and action has been initiated against the makers, the DCGI said




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Doctors struggle to treat long Covid patients in India; researchers point to inadequate studies

Global efforts to understand and manage long Covid post-pandemic, with varied symptoms and limited treatment guidelines worldwide