id Selective ratiometric red-emission detection of In3+ in aqueous solutions and in live cells using a fluorescent peptidyl probe and metal chelating agent By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00288G, PaperJoohee Park, Hyeongseok Yu, See-Hyoung Park, Keun-Hyeung LeeA ratiometric fluorescent detection method for In3+ in aqueous buffered solution, ground water, and live cells was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id A highly efficient preconcentration route for rapid and sensitive detection of endotoxin based on an electrochemical biosensor By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00315H, PaperWenrui Ma, Lulu Liu, Yi Xu, Li Wang, Li Chen, Sheng Yan, Lingling Shui, Zhijun Wang, Shunbo LiAn impedimetric aptasensor for detection of endotoxin in a microfluidic chip was proposed, in which the Apt/AuNPs/SPCE sensing surface was fabricated in screen-printed electrode with good biological activity and stability....The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id FRET based fluorescent ratiometric probes for rapid detection of endogenous hydrogen sulphide in living cells By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00531B, PaperYuming Zhang, Yuncong Chen, Bai Yang, Xueling Xue, Weijiang He, Zijian GuoReal time monitor of hydrogen sulphide (H2S) level change is of crucial importance for the study of its complicated roles in physiology. Herein, we developed a FRET strategy for designing...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Laser-induced graphene hybrid photoelectrode for enhanced photoelectrochemical detection of glucose By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00252F, PaperHui Li, Chengxiang Guo, Changchun Liu, Lei Ge, Feng LiThe in situ and synchronous fabrication of Ni0/NiO–CdS–graphene hybrid photoelectrodes is developed using a facile and scalable direct-laser-writing method for photoelectrochemical detection of glucose.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Liquid-crystal-based immunosensor for detection of cardiac troponin I By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00425A, PaperChunli Xia, dong Zhou, yueming Su, guangkai Zhou, Lishuang Yao, Weimin sun, yongjun LiuCardiac troponin I (cTnI) is one of the most sensitive and specific markers of myocardial cell injury, which can detect even minor myocardia damage. It is recognized as the main...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Driving Force to Detect Alzheimer's Disease Biomarkers: The Application Of A Thioflavine T@Er-MOF Ratiometric Fluorescent Sensor for Smart Detection of Presenilin 1, amyloid β-protein and Acetyl Choline By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00440E, PaperXing Ze Wang, jing du, Nannan Xiao, Yan Zhang, Ling Fei, Jed D. LaCoste, Zhuo Huang, Qian wang, Xin Rui Wang, Bin DingCurrently, the highly sensitive detection of Alzheimer's Disease (AD) biomarkers, namely presenilin 1, amyloid β-protein (Aβ), and acetylcholine (ACh), are vital to helping us prevent and diagnose AD. In this...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Naked-Eye Sensing of Phytic Acid at Sub-Nanomolar Level in 100% Water Medium by Charge Transfer Complex Derived from off-the-shelf Ingredients By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00671H, PaperNilanjan DeyNaked-eye sensing of phytic acid, one of the most abundant antinutrients, was achieved in 100% water medium using charge transfer complex, comprised of pyranine and methyl viologen. Since both the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id A homogeneous photoelectrochemical hydrogen sulfide sensor based on the electronic transfer mediated by tetrasulfophthalocyanine By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00302F, PaperXinyang Wang, Huanan Zhao, Zhonghui Chen, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin, Jian WangA homogeneous photoelectrochemical sensor for H2S detection based on the electronic transfer mediated by [Fe(III)PcS4]+ was developed with an un-modified photoelectrode.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id An Integrated Microfluidic Platform for Selective and Real-Time Detection of Thrombin Biomarkers using a Graphene FET By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00251H, PaperNiazul Islam Khan, Mohammad Mousazadehkasin, Sujoy Ghosh, John G. Tsavalas, Edward SongLab-on-a-chip technology offers an ideal platform for low-cost, reliable, and easy-to-use diagnostics of key biomarkers needed for early screening of diseases and other health concerns. In this work, a graphene...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Rapid on-site and naked-eye detection of common nitro pesticides with ionic liquids By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00452A, Paper Kovida, Vikas Sharma, Apurba Lal KonerRapid ‘in-field’ detection of environmentally hazardous organophosphorus and nitro-containing pesticides is highly essential due to the lethal effects caused by the inhibition of the activity of acetylcholinesterase (AChE).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Core–shell magnetic microporous covalent organic framework with functionalized Ti(IV) for selective enrichment of phosphopeptides By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00038H, PaperFengjuan Ding, Yameng Zhao, Haiyan Liu, Weibing ZhangWe fabricated a core-shell magnetic Ti4+-functionalized covalent organic framework composite to selectively capture phosphopeptides in biosamples. This method is applicable to achieve rapid, selective and efficient phosphopeptide analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Acid–base titration using a microfluidic thread-based analytical device (μTAD) By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00522C, PaperPurim Jarujamrus, Akarapong Prakobkij, Sodsai Puchum, Sawida Chaisamdaeng, Rattapol Meelapsom, Wipark Anutrasakda, Maliwan Amatatongchai, Sanoe Chairam, Daniel CitterioThis work presents a novel analytical approach for precise and quick (within 2 minutes) determination of acid and base concentrations (of very small amount) by titration using a microfluidic thread-based analytical device (μTAD).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id A Simple and Ubiquitous Device for Picric Acid Detection in Latent Fingerprints using Carbon Dots By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00750A, PaperArunkumar Kathiravan, Annasamy Gowri, Srinivasan Venkatesan, Trevor Smith, Muthpandian Ashokkumar, Asha Jhonsi MariadossThis work addresses the synthetic optimization of carbon dots (CDs) and their application in sensing picric acid from latent fingerprint by exploiting a smartphone-based RGB tool. The optimization in the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00721H, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xiaoxiao Guo, Jodie R Malcolm, Marrwa M Ali, Goreti Ribeiro Morais, Steve Shnyder, Paul Loadman, L H Patterson, Robert Andrew FalconerThe polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id Phenyl doped graphitic carbon nitride nanosheets for sensing of copper ions in living cells By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00795A, PaperZhiping Song, Yuanteng Xu, Liangqia GuoCopper (Cu) is a vital mental element for human and animals. Monitoring and evaluating the concentration level of Cu2+ in biological body is an effective way to prevent a variety...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
id [ASAP] Nucleic Acid Detection Using CRISPR/Cas Biosensing Technologies By feedproxy.google.com Published On :: Tue, 17 Mar 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00507 Full Article
id [ASAP] A Novel Biosynthetic Pathway for the Production of Acrylic Acid through ß-Alanine Route in <italic toggle="yes">Escherichia coli</italic> By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00019 Full Article
id [ASAP] Genome-Wide CRISPRi-Based Identification of Targets for Decoupling Growth from Production By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00143 Full Article
id [ASAP] Introduction of the Menaquinone Biosynthetic Pathway into <italic toggle="yes">Rhodobacter sphaeroides</italic> and <italic toggle="yes">de Novo</italic> Synthesis of Menaquinone for Incorporation into He By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00066 Full Article
id [ASAP] Engineering Stable <italic toggle="yes">Pseudomonas putida</italic> S12 by CRISPR for 2,5-Furandicarboxylic Acid (FDCA) Production By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00006 Full Article
id [ASAP] Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in <italic toggle="yes">E. coli</italic> Nissle Residing in the Mammalian Gut By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00040 Full Article
id [ASAP] Truncating the Structure of Lipopolysaccharide in <italic toggle="yes">Escherichia coli</italic> Can Effectively Improve Poly-3-hydroxybutyrate Production By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00071 Full Article
id [ASAP] Multicomponent Microscale Biosynthesis of Unnatural Cyanobacterial Indole Alkaloids By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00038 Full Article
id [ASAP] Imidazo[1,2-<italic toggle="yes">a</italic>]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells By feedproxy.google.com Published On :: Mon, 20 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01910 Full Article
id [ASAP] Synthesis and Structure–Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01961 Full Article
id [ASAP] Pyridine-Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00280 Full Article
id [ASAP] Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma By feedproxy.google.com Published On :: Thu, 23 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02161 Full Article
id [ASAP] Correction to Toggling Preassembly with Single-Site Mutation Switches the Cytotoxic Mechanism of Cationic Amphipathic Peptides By feedproxy.google.com Published On :: Fri, 24 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00608 Full Article
id [ASAP] Discovery and Structure–Activity Relationship Study of (<italic toggle="yes">Z</italic>)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00227 Full Article
id [ASAP] Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02035 Full Article
id [ASAP] Structure–Activity Relationship of SPOP Inhibitors against Kidney Cancer By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00161 Full Article
id [ASAP] Discovery of (2<italic toggle="yes">R</italic>)-<italic toggle="yes">N</italic>-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1<italic toggle="yes">H</italic>-indol-7 By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01392 Full Article
id [ASAP] Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00015 Full Article
id [ASAP] Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01936 Full Article
id [ASAP] Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01937 Full Article
id [ASAP] Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00442 Full Article
id [ASAP] Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00337 Full Article
id [ASAP] Chimeric Peptidomimetics of SOCS 3 Able to Interact with JAK2 as Anti-inflammatory Compounds By feedproxy.google.com Published On :: Mon, 30 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00664 Full Article
id [ASAP] Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-<italic toggle="yes">a</italic>]pyridines against the 1A Family By feedproxy.google.com Published On :: Tue, 31 Mar 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00686 Full Article
id [ASAP] Glycans Meet Sphingolipids: Structure-Based Design of Glycan Containing Analogues of a Sphingosine Kinase Inhibitor By feedproxy.google.com Published On :: Wed, 01 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00665 Full Article
id [ASAP] Peptoid NPhe<sup>4</sup> in AGRP-Based c[Pro<sup>1</sup>-Arg<sup>2</sup>-Phe<sup>3</sup>-Phe<sup>4</sup>-Xxx<sup>5</sup>-Ala<sup>6</sup>-Phe<sup>7</sup> By feedproxy.google.com Published On :: Wed, 01 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00641 Full Article
id [ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00669 Full Article
id [ASAP] Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00045 Full Article
id [ASAP] Substituted Naphthalenediimide Compounds Bind Selectively to Two Human Quadruplex Structures with Parallel Topology By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00041 Full Article
id [ASAP] Escaping from Flatland: Substituted Bridged Pyrrolidine Fragments with Inherent Three-Dimensional Character By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00039 Full Article
id [ASAP] Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening By feedproxy.google.com Published On :: Fri, 03 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00076 Full Article
id [ASAP] Chiral Analogues of PFI-1 as BET Inhibitors and Their Functional Role in Myeloid Malignancies By feedproxy.google.com Published On :: Tue, 07 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00625 Full Article
id [ASAP] Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface By feedproxy.google.com Published On :: Tue, 07 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00111 Full Article
id [ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents By feedproxy.google.com Published On :: Wed, 08 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00639 Full Article
id [ASAP] Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00594 Full Article
