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Delhi violence: Court rejects bail plea of Shahrukh Pathan




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Woman thrashed over husband’s affair; dies

A woman died during treatment at Patna Medical College and Hospital (PMCH) on Saturday after she was allegedly thrashed by her husband Vinay Ram and other in-laws for opposing his illicit relationship with his aunt and brother’s wife (sister-in-law).




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Shramik train leaves Coimbatore for UP's Akbarpur




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A Systemic Look At Schizophrenia

Proteomic analysis of peripheral cells reveals aspects of psychiatric disorder.




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Common threads in breast cancer proteomes

The changes in protein expression common to several cancerous cell lines focus attention on cell spreading and focal adhesion kinase.




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Virat-Anushka's adorable throwback picture

Anushka Sharma might be away from the silver screen but she is definitely grabbing a lot of attention on social media for all the right reasons. The talented actress is spending quality time with her husband Virat Kohli at home and the two are making the most of the quarantine period.




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JFA pays tributes to martyr journalist Pankaj Kulashrestha

JFA pays tributes to martyr journalist Pankaj Kulashrestha




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Coronavirus | Andhra’s dire finances drive it to seek Central help

Revenue deficit, COVID-19 burden and industry distress leave State on edge




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Five Shramik trains leave State

Five Shramik Special trains — four from Bengaluru and one from Mangaluru — left for north Indian States on Saturday from Karnataka to ferry migrant wo




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Judge rules against PPG in chromium cleanup lawsuit




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Aurangabad train mishap: NHRC notice to Maharashtra govt




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Three more trains leave Coimbatore on Saturday with migrant workers

One train to Bihar and two to Uttar Pradesh; each train ferries 1,140 passengers




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A COVID-19 social exercise that seems to have got it right on three counts

It is a case of trying to understand the society around us through experiential knowledge transfer




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Aid to poor through post offices from Monday

Special CorrespondentHyderabad




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Update your Google Chrome browser immediately: CERT-In

Update your Google Chrome browser immediately: CERT-In




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Shriya Saran urges fans to help small businesses during the COVID-19 crisis

Shriya Saran urges fans to help small businesses during the COVID-19 crisis




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Mother's Day 2020: Sara Ali Khan shares a beautiful throwback picture and thanks her 'Maa ki Maa' for creating her mommy

Mother's Day 2020: Sara Ali Khan shares a beautiful throwback picture and thanks her 'Maa ki Maa' for creating her mommy




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Esports: Wehrlein ends Guenther's run of virtual Formula E success

Esports: Wehrlein ends Guenther's run of virtual Formula E success




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More than half of all Shramik trains departed from Gujarat

More than half of all Shramik trains departed from Gujarat




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Awareness through music

Awareness through music




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Actor Rajshri Deshpande reaches out to the needy via a crowdfunding platform

Actor Rajshri Deshpande reaches out to the needy via a crowdfunding platform




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Tesla sues California county in factory closure fight, threatens to leave

Tesla said the county's position left it no choice but to take legal action to ensure Tesla and its employees can go back to work




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Punjabi singer Sippy Gill booked for promoting violence through his song




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Unemployed teachers in Punjab threaten to jump into canal




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One more tests positive for COVID-19 in Punjab, total count rises to three




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Three more test positive in Punjab; total rises to six




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Three more COVID-19 positive cases in Punjab




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Punjab ministers not to take salaries for three months




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Dept inquiry initiated against officer accused of stripping three persons at police station last year




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Three arrested in Punjab for smuggling liquor amid lockdown




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Five returnees from Shri Hazur Sahib test positive for COVID-19, all pilgrims to be quarantined: Punjab govt




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263 stranded people leave for Heathrow from Amritsar




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63 Hazur Sahib pilgrims test positive for COVID-19 in Punjab's Nawanshahr




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Ban on entry of unregistered Keralites through Talapady

Surge in number of returnees without registration




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347 returnees quarantined in Thrissur

The quarantine centres for Keralites returning from abroad and other States have accommodated 347 people in Thrissur district. They were sent to the c




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Coronavirus lockdown | Three migrant workers on way to Uttar Pradesh die on Maharashtra-Madhya Pradesh border

The trio were among thousands of migrant workers who have set out on foot for their home states from Maharashtra in the last few weeks amid lockdown on account for coronavirus.




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Coronavirus | Fatalities dog Andhra Pradesh, Telangana battle against virus

Two expatriates test positive in Kerala; Karnataka focuses on Bengaluru cases




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Elon Musk threatens to exit California over virus restrictions

He wrote that whether the company keeps any manufacturing in Fremont depends on how Tesla is treated in the future.





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IndiGo's pay cuts for senior employees to remain effective through FY21

The aviation sector has been hit hard due to the suspension of all commercial passenger flights during the coronavirus-induced lockdown in the country




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128 Covid deaths, 3,277 cases in 24 hrs; toll 2,109

Of the 2,109 fatalities, Maharashtra tops the tally with 779 deaths. Gujarat comes second with 472 deaths, followed by Madhya Pradesh at 215, West Bengal at 171, Rajasthan at 106, Uttar Pradesh at 74, Delhi at 73, and Andhra Pradesh and Tamil Nadu at 44.




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Tracking US President Donald Trump’s response to Covid-19 through his top 10 quotes




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Shraddha Kapoor’s airport looks mirror the ‘girl next door’ theme




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Low-dose X-ray structure analysis of cytochrome c oxidase utilizing high-energy X-rays

To investigate the effect of high-energy X-rays on site-specific radiation-damage, low-dose diffraction data were collected from radiation-sensitive crystals of the metal enzyme cytochrome c oxidase. Data were collected at the Structural Biology I beamline (BL41XU) at SPring-8, using 30 keV X-rays and a highly sensitive pixel array detector equipped with a cadmium telluride sensor. The experimental setup of continuous sample translation using multiple crystals allowed the average diffraction weighted dose per data set to be reduced to 58 kGy, and the resulting data revealed a ligand structure featuring an identical bond length to that in the damage-free structure determined using an X-ray free-electron laser. However, precise analysis of the residual density around the ligand structure refined with the synchrotron data showed the possibility of a small level of specific damage, which might have resulted from the accumulated dose of 58 kGy per data set. Further investigation of the photon-energy dependence of specific damage, as assessed by variations in UV-vis absorption spectra, was conducted using an on-line spectrometer at various energies ranging from 10 to 30 keV. No evidence was found for specific radiation damage being energy dependent.




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Fast identification of mineral inclusions in diamond at GSECARS using synchrotron X-ray microtomography, radiography and diffraction

Mineral inclusions in natural diamond are widely studied for the insight that they provide into the geochemistry and dynamics of the Earth's interior. A major challenge in achieving thorough yet high rates of analysis of mineral inclusions in diamond derives from the micrometre-scale of most inclusions, often requiring synchrotron radiation sources for diffraction. Centering microinclusions for diffraction with a highly focused synchrotron beam cannot be achieved optically because of the very high index of refraction of diamond. A fast, high-throughput method for identification of micromineral inclusions in diamond has been developed at the GeoSoilEnviro Center for Advanced Radiation Sources (GSECARS), Advanced Photon Source, Argonne National Laboratory, USA. Diamonds and their inclusions are imaged using synchrotron 3D computed X-ray microtomography on beamline 13-BM-D of GSECARS. The location of every inclusion is then pinpointed onto the coordinate system of the six-circle goniometer of the single-crystal diffractometer on beamline 13-BM-C. Because the bending magnet branch 13-BM is divided and delivered into 13-BM-C and 13-BM-D stations simultaneously, numerous diamonds can be examined during coordinated runs. The fast, high-throughput capability of the methodology is demonstrated by collecting 3D diffraction data on 53 diamond inclusions from Juína, Brazil, within a total of about 72 h of beam time.




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BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring – recent advances and future perspectives

Being able to visualize biology at the molecular level is essential for our understanding of the world. A structural biology approach reveals the molecular basis of disease processes and can guide the design of new drugs as well as aid in the optimization of existing medicines. However, due to the lack of a synchrotron light source, adequate infrastructure, skilled persons and incentives for scientists in addition to limited financial support, the majority of countries across the African continent do not conduct structural biology research. Nevertheless, with technological advances such as robotic protein crystallization and remote data collection capabilities offered by many synchrotron light sources, X-ray crystallography is now potentially accessible to Africa-based scientists. This leap in technology led to the establishment in 2017 of BioStruct-Africa, a non-profit organization (Swedish corporate ID: 802509-6689) whose core aim is capacity building for African students and researchers in the field of structural biology with a focus on prevalent diseases in the African continent. The team is mainly composed of, but not limited to, a group of structural biologists from the African diaspora. The members of BioStruct-Africa have taken up the mantle to serve as a catalyst in order to facilitate the information and technology transfer to those with the greatest desire and need within Africa. BioStruct-Africa achieves this by organizing workshops onsite at our partner universities and institutions based in Africa, followed by post-hoc online mentoring of participants to ensure sustainable capacity building. The workshops provide a theoretical background on protein crystallography, hands-on practical experience in protein crystallization, crystal harvesting and cryo-cooling, live remote data collection on a synchrotron beamline, but most importantly the links to drive further collaboration through research. Capacity building for Africa-based researchers in structural biology is crucial to win the fight against the neglected tropical diseases, e.g. ascariasis, hookworm, trichuriasis, lymphatic filariasis, active trachoma, loiasis, yellow fever, leprosy, rabies, sleeping sickness, onchocerciasis, schistosomiasis, etc., that constitute significant health, social and economic burdens to the continent. BioStruct-Africa aims to build local and national expertise that will have direct benefits for healthcare within the continent.




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Generating three-color pulses in high-gain harmonic-generation free-electron lasers with a tilted electron bunch

A multi-color light source is a significant tool for nonlinear optics experiments, pump–dump/repump–probe experiments and in other fields. Here, a novel method is proposed to create three-color pulses based on a high-gain harmonic-generation (HGHG) free-electron laser with a tilted electron bunch. In this method, the initial bunch tilt is created by transverse wakefields after the bunch passes through a corrugated structure with an off-axis orbit, and is further enlarged in a following drift section. Then the tilted bunch experiences the off-axis field of a quadrupole magnet to cool down the large transverse velocity induced before. After that, it enters an HGHG configuration adopting a transverse gradient undulator (TGU) as the radiator, where only three separated fractions of the tilted bunch will resonate at three adjacent harmonics of the seed wavelength and are enabled to emit three-color pulses simultaneously. In addition, the use of the natural transverse gradient of a normal planar undulator instead of the TGU radiator to emit three-color pulses is also studied in detail. Numerical simulations including the generation of the tilted bunch and the free-electron laser radiation confirm the validity and feasibility of this scheme both for the TGU radiator and the natural gradient in the extreme-ultraviolet waveband.




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An enlightening procedure to explain the extreme power of synchrotron radiation

A simple approach exploits quantum properties to justify the dependence on γ4 of the total synchrotron emitted power. It also clarifies some apparent puzzles and brings to light the underlying, multiple relativistic phenomena.




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Performance of nearly fixed offset asymmetric channel-cut crystals for X-ray monochromators

X-ray double-crystal monochromators face a shift of the exit beam when the Bragg angle and thus the transmitted photon energy changes. This can be compensated for by moving one or both crystals accordingly. In the case of monolithic channel-cut crystals, which exhibit utmost stability, the shift of the monochromated beam is inevitable. Here we report performance tests of novel, asymmetrically cut, channel-cut crystals which reduce the beam movements by more than a factor of 20 relative to the symmetric case over the typical energy range of an EXAFS spectrum at the Cu K-edge. In addition, the presented formulas for the beam offset including the asymmetry angle directly indicate the importance of this value, which has been commonly neglected so far in the operation of double-crystal monochromators.




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Coherence properties of the high-energy fourth-generation X-ray synchrotron sources

An analysis of the coherence properties of the fourth-generation high-energy storage rings with emittance values of 10 pm rad is performed. It is presently expected that a storage ring with these low emittance values will reach diffraction limit at hard X-rays. Simulations of coherence properties were performed with the XRT software and an analytical approach for different photon energies from 500 eV to 50 keV. It was demonstrated that a minimum photon emittance (diffraction limit) reached at such storage rings is λ/2π. Using mode decomposition it is shown that, for the parameters of the storage ring considered in this work, the diffraction limit will be reached for soft X-ray energies of 500 eV. About ten modes will contribute to the radiation field at 12 keV photon energy and even more modes give a contribution at higher photon energies. Energy spread effects of the electron beam in a low-emittance storage ring were analysed in detail. Simulations were performed at different relative energy spread values from zero to 2 × 10−3. A decrease of the degree of coherence with an increase of the relative energy spread value was observed. This analysis shows that, to reach the diffraction limit for high photon energies, electron beam emittance should go down to 1 pm rad and below.