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AT#674 - Travel to the Le Marche Region of Italy

Hear about travel to the Le Marche Region of Italy as the Amateur Traveler talks to Chantelle and Giovanni from theitalianontour.com about this off the beaten path destination.




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AT#579 - Travel to Istanbul, Turkey (Repeat)

Hear about travel to Istanbul, Turkey as the Amateur Traveler talks to Christopher Mitchell from travelingmitch.com about the city where he lived for 3 years.




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AT#676 - Travel to La Rochelle, France

Hear about travel to La Rochelle, France as the Amateur Traveler talks to Jacob Kell from facilitateluxury.com about this beautiful medieval city. What things are there to do in La Rochelle.




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AT#677 - Travel to Nagoya, Japan

Hear about travel to Nagoya, Japan as the Amateur Traveler talks to Lena Yamaguchi from nagoyafoodie.com about her adopted home.




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AT#678 - Travel to to Porto, Portugal

Hear about travel to Porto, Portugal as the Amateur Traveler talks to João Reis and Sara Silva from nofootprintnomads.com about their home city.




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AT#573 - Travel to the Yukon Territory (Repeat)

Hear about travel to the Yukon Territory in Canada as the Amateur Traveler talks to Stephen Reynolds from Tourism Yukon about a recent trip that I did to his home.




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AT#680 - Travel to the Canary Islands

Hear about travel to the Canary Islands as the Amateur Traveler talks to Alice Ford from alicesadventuresonearth.com about the best of the Canary Islands.




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AT#681 - Travel to Chennai India

Hear about travel to Chennai India as the Amateur Traveler talks to Amanda from millennialtraveller.com about this city in southern India. 




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AT#683 - Travel to Saint Lucia

Hear about travel to Saint Lucia as the Amateur Traveler talks to Keiwa Simpson from discoverstluciatours.com about her beautiful island.




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AT#684 - Travel to Berlin

Hear about travel to Berlin as the Amateur Traveler talks to Dan Noll and Audrey Scott from uncorneredmarket.com about the city they now call home.




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AT#685 - Travel to Krabi, Thailand

Hear about travel to Krabi, Thailand as the Amateur Traveler talks to Annette Fortner from chaseforadventure.com about this tropical paradise.




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AT#589 - Travel to Lombok, Indonesia (Repeat)

Hear about travel to Lombok in Indonesia as the Amateur Traveler talks to Jason Andrew Jenkins from AnEpicEducation.com about his family's recent 5 week trip to this island paradise.




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AT#686 - Travel to Moldova

Hear about travel to Moldova as the Amateur Traveler talks to Christina Lutcan from findingelevation.com about her country of origin.




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AT#687 - Travel to Switzerland

Hear about travel to Switzerland as the Amateur Traveler talks to Zack Best about this beautiful country where he has studied and worked.




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AT#688 - Travel to the Mississippi Gulf Coast

Hear about travel to the Mississippi Gulf Coast as the Amateur Traveler talks to Charles McCool from McCoolTravel.com about this tasty area with great beaches.




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AT#689 - Travel to Namibia (Sossusvlei and Namib-Naukluft National Park)

Hear about travel to Namibia as the Amateur Traveler talks to Karthik Iyer about his most recent trip to this desert country.




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AT#690 - Travel to Tainan, Taiwan

Hear about what to do in Tainan, Taiwan as the Amateur Traveler talks to Katy Liang from photospired.com about her native Taiwan.




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AT#691 - Travel to Bulgaria

Hear about travel to Bulgaria as the Amateur Traveler talks to Tom and Patty Burkett about their road trip from Sofia to the Black Sea.




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AT#692 - Travel to Yunnan, China

Hear about travel to the Yunnan province of China as the Amateur Traveler talks to Zach and Leah from peregrination-travel.com about their trip to this mountainous corner of the country.




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AT#694 - Travel to Northern Pakistan

Hear about travel to Northern Pakistan and the  Karakoram Highway as the Amateur Traveler talks to David Harden from travelwornsatchel.com about his road trip in this remote and beautiful country.




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AT#695 - Travel to Ecuador

Hear about places to visit in Ecuador on your Ecuador vacation as the Amateur Traveler talks to Keenan Ennis about this country that he now calls home.




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AT#696 - Travel to Asheville, North Carolina

Hear about things to do in Asheville, NC as the Amateur Traveler talks to music journalist and cocktail aficionado Bill Kopp about his adopted hometown.




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AT#697 - Travel to the Alsace Region of France

Hear about travel to the Alsace Region of France as the Amateur Traveler talks to Brighde Reed from worldvegantravel.com about this lovely wine region.




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AT#698 - Travel to Costa Rica

Hear about travel to Costa Rica as the Amateur Traveler talks to Costa Rica travel experts Sam and Yeison from mytanfeet.com about their beautiful country.




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AT#701 - Travel to West Virginia

Hear about travel to southern West Virginia as the Amateur Traveler talks to Ethan Starcher from WaywardWings.net about his home state.




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AT#702 - Travel to Senegal and The Gambia

Hear about travel to West Africa to Senegal and the Gambia as the Amateur Traveler talks to Brian Asher from theworldhiker.com about this under-visited region.




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AT#703 - Travel to Tbilisi and Eastern Georgia

Hear about travel to Tbilisi and the eastern part of the Republic of Georgia as the Amateur Traveler talks to Tommo & Megsy from FoodFunTravel.com who have settled in Georgia.




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Watch: Cops Save Helpless Stray Cat Found with Head Stuck in Soup Can

A stray cat from Las Vegas has lived to see another day thanks to kindhearted police officers who paused to remove a soup can wedged firmly onto the cat’s head. The lure of a salty, potent-smelling soup can was likely too tempting to resist for the cat who was hooked at the first taste. As…

The post Watch: Cops Save Helpless Stray Cat Found with Head Stuck in Soup Can appeared first on The Western Journal.




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New Study Confirms We Were Right: Reading, Math Scores Have Collapsed Thanks to Obama, Common Core

Conservatives had this Common Core thing all wrong, it was said. We’d be proven wrong by history. Common Core, pushed by President Barack Obama, was going to work. It wasn’t like all the other liberal education plans. A new study by the Pioneer Institute reveals that, no, we were right all along. The study, released…

The post New Study Confirms We Were Right: Reading, Math Scores Have Collapsed Thanks to Obama, Common Core appeared first on The Western Journal.




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Ted Cruz Stops by Shelly Luther’s Salon for a Trim, ‘True Authenticity’ Leaves Her Sobbing

Sen. Ted Cruz was apparently about to get into mullet territory. He hadn’t had a haircut in three months. Things were looking grim for the Texas senator. Thankfully, Shelley Luther is able to do something about that. Luther is both famous and free after a viral clip of her standing up to a judge who…

The post Ted Cruz Stops by Shelly Luther’s Salon for a Trim, ‘True Authenticity’ Leaves Her Sobbing appeared first on The Western Journal.




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Predictions 2020: Facebook Caves, Google Zags, Netflix Sells Out, and Data Policy Gets Sexy

A new year brings another run at my annual predictions: For 17 years now, I’ve taken a few hours to imagine what might happen over the course of the coming twelve months. And my goodness did I swing for the fences last year — and I pretty much whiffed. Batting .300 is great in the majors, but it … Continue reading "Predictions 2020: Facebook Caves, Google Zags, Netflix Sells Out, and Data Policy Gets Sexy"




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Will The Coronavirus Save Big Tech?

Who’s Really Behind That “Death of the Techlash” Narrative?   One of my least favorite kinds of journalism is the easy win. It’s the kind of story that just lands in your lap. It feels contrarian, yet of the moment, it’s often predicated by the appearance of a primary source dangling easy data, and unlike most … Continue reading "Will The Coronavirus Save Big Tech?"




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For Some Refugees, Safe Haven Now Depends on a DNA Test

Changes to a program designed to reunite refugees with family in the U.S. have slowed -- and in some cases outright denied -- legitimate entries into the country.




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A Campaign of Disappearances in Syria Leaves Thousands Missing

At least 65,116 individuals have been "forcibly disappeared" by the Syrian government, according to a new report by Amnesty International.




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Silicone mini-pinch bowls have 101 uses

These little silicone rubber bowls come in handy in so many ways.

I use them with my digital scale to measure the bulk powder supplements I take. We use them at the dinner table to hold condiments. We use them while preparing meals to hold spices and minced herbs. I keep finding new ways to use them. For instance, when I fry or scramble eggs, I now crack the eggs over one of these bowls so I can pull out shell pieces and woogers (I wish I had a wooger snatcher but the bowl will have to do). Read the rest




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Puppy training doesn’t have to descend your house into chaos thanks to these online classes

One positive upside of the past two months is how sheltering at home has all but emptied area animal shelters. It’s tough to get solid numbers nationally, but shelters in cities and regions all across America are reporting massive surges in animal adoptions

Even the steep increase in Google searches for “adopt a pet,” up a whopping 335 percent in April, proves what we probably all knew anyway — that in times of stress, having a furry friend is a huge comfort for millions.

Unfortunately, one of the downsides of the past two months is there are no trainers available to help whip some of these new family pets, particularly puppies, into shape. From barking and jumping to house training and scratching, The Complete Guide to Puppy and Dog Training Bundle is a full plan for getting the newest member of your family integrated into the house safely and sanely all by yourself.

The collection includes eight courses all geared toward getting a new dog or puppy behaving the right way. And if you’ve ever had any thoughts about starting a dog training business of your own, this coursework is a perfect starting spot.

Puppies: A-Z Guide to Puppy & Dog Training kicks off the learning, explaining the best way to train, teach and socialize your puppy so they grow into a joyful, well balanced, and well-behaved dog. 

Of course, most puppies each have their particular issues, so a handful of courses look more closely at some of the tactics for helping your puppy overcome certain challenging behaviors. Read the rest




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Talking Adventure Games with Dave Gilbert

Game designer and publisher Dave Gilbert founded Wadjet Eye Games in 2006.  This interview features conversation about point and click adventure games; digital game development, marketing and publishing; and the relationship between art, passion and real world commerce.

Jeffery Klaehn: How did you first become interested in point and click adventure games?

Dave Gilbert: I played King’s Quest at a very impressionable age! I typed the word “jump” and I saw Graham actually jump, and I was so blown away that I’ve been playing them ever since.

JK: You founded Wadjet Eye Games in 2006 to sell your game, The Shivah, commercially, then moved to pursue game design on a full-time basis and released The Blackwell Legacy, the first in what would become a series of five games.  What are your thoughts on these games and on the market then compared to now?

Dave Gilbert: I am Blackwell Legacy’s biggest critic. It was the first game I wrote with the intention of selling commercially – The Shivah was originally freeware, so I don’t count it – and it shows every inch of my inexperience. The gameplay is clunky, the story is told in three giant infodumps, and the main characters weren’t very likable. But that said, I know with absolute certainty that it was the very best game I could have made with the experience, resources and time I had available. So I stand by it.

As for the market, everything is different. Back in 2006, indie games in general were a very new thing. Read the rest




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Sport24.co.za | Nadal believes Djokovic will have to be vaccinated

Rafael Nadal insists all players, including Novak Djokovic, will need to take a coronavirus vaccine should one become available.




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9 Frugal Tips for Families to Save Money

Family is an integral part of any person’s life. When we live with our families, it’s either we’re dependent on somebody or somebody is dependent on us. Many conflicts arise in a family due to improper finance management. When you have a family, you might often come across situations where you might feel there is […]

The post 9 Frugal Tips for Families to Save Money appeared first on Dumb Little Man.




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Pros and Cons of Traveling by Car You Should Know

Many people all over the world are fond of traveling. Which kind of vehicle for trips is the most comfortable? Probably, the only answer here is that everything is individual. However, when you travel by car, you are your own boss on the road. In this article, we gathered the common pros and cons of […]

The post Pros and Cons of Traveling by Car You Should Know appeared first on Dumb Little Man.




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45 Funny, Heartfelt, Unforgettable Travel Stories

I tell travel stories for a living. I do this because I can’t NOT tell travel stories — every experience I have is shaped in the moment and waits in anticipation to shoot out of my fingertips. And I live to share those stories with an audience. As humans, we’re hard-wired to be influenced by …

45 Funny, Heartfelt, Unforgettable Travel Stories Read More »

The post 45 Funny, Heartfelt, Unforgettable Travel Stories appeared first on Adventurous Kate.




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3 Easy Steps to Save Money for Travel

Finding ways to save money is much easier than you think, because you’re probably spending money you don’t have to spend.

The article 3 Easy Steps to Save Money for Travel originated at EverInTransit.com








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7 Must-Have Gadgets to Trick Out Your RV Kitchen for 2019

We love to cook. But RV kitchens are notoriously — almost impossibly — small. The limited workspace can challenge even the most skilled food truck chefs. The key to actually enjoying cooking in such a confined space is finding the right tools that pack maximum versatility into a compact, lightweight, and durable package. Here are seven of our favorite RV kitchen gadgets. The Best RV Kitchen Gadgets for Every On-the-Go Chef Flexible Wood Cutting Board The easiest way to keep […]

The post 7 Must-Have Gadgets to Trick Out Your RV Kitchen for 2019 appeared first on Vagabondish.




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Top Travel Mistakes Foreign Tourists Make

Travel is fun, when you plan things properly. If you have visited many countries, then surely you have made many mistakes such as booking resorts at wrong places or buying costly souvenirs which are easily available in your country. We all make silly mistakes when we visit a new country and there is no need to feel ashamed. What you need to do is make sure that you don’t repeat those mistakes.

When it comes to mistakes, I am not talking about flight or hotel ticket booking blunders. There are many more small oversights that can ruin your vacation. Let’s explore some of the common mistakes that tourists make every year.

No research about the place: You may know the name of the country, its capital and its currency exchange rate, but do you really know the place you are visiting? For example, in India, there are many prepaid taxi booths that charge right amount for a trip, but if you just pick any cab from the road, the driver may charge you double because you don’t know the route to your destination. Similarly, it is important to know the things you can and can’t do in the place you are visiting. For example, taking pictures is prohibited in many religious places.

Over-packing: Never carry too many clothes, because you are going to carry your bags, and if those are too heavy, you will curse yourself. Besides, the airlines charge hefty amount if your luggage crosses the weight limit. Always pack only those things that are necessary for the place you are visiting. For example, if you are going to Tadoba tiger reserve forest and staying at Tadoba tiger resort, then you don’t need to pack a cocktail party dress. It is better to pack a few jeans and t-shirts.

Speaking English only: Try to learn a few sentences in the local language. For example, words of greetings, how to ask for road directions and how to ask the price of something. The more you communicate with the locals in their own language, the more confident you will feel.

Disrespecting the customs: India is a conservative county, and the culture of Indians is very different from Americans. However, that does not mean you can mock or disrespect their culture. For example, Americans enter churches wearing shoes, but in India, you can’t wear shoes in a temple. Respect the rule while visiting any temple in India. After all, you are visiting a new country to understand its culture.

Reading guidebooks only: Guidebooks are for references and they can’t give you all the information about the place. For example, a guidebook may tell you that Taj Mahal is wonderful, but unless you raise your face from the book, can you truly appreciate its beauty?

Booking hotels and flights separately: Take a look at the famous travel portals and you will find that they are offering great hotel + airplane deals. When you book return tickets and also hotel rooms, you can save a few hundred dollars. Besides, it is a hassle free process as you are getting everything from one site.

Interrupting the guide: You can be the history professor in a college, but if you interrupt the guide when he is talking about a historical place, then you are being rude. All the other tourists have paid for the guided tour and by interrupting the guide frequently you are making everyone angry.

So, when you visit a foreign country this year, make sure that you don’t make the mistakes mentioned above. Enjoy nature, history and culture of the place you are visiting and you will feel rejuvenated by the end of your vacation.

If you like traveling to exotic places, check out our Machu Picchu Tours page



  • Tips and Things To Know

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5 Ways To Get The Most Out Of Solo Travelling

Planning a little solo jaunt across the land? If this is your first time planning your virgin solo adventure, I understand completely how excited and nervous you are. I was once in your shoes.

Before you slap on your backpack and march out that door, here’s a small checklist of things you might want to do to ensure a better trip.

Image courtesy of bluetidalwave.com

Research, Research, Research

It doesn’t matter if you’re headed into uncharted territory or a bustling metropolis, it only helps if you already know what to expect when you set foot in your destination. A quick google search should give you enough information on things like the local culture, geography, weather and political climate to start with. Oh, and do not forget to check out the local laws, either-written and unwritten. People have in the past gotten into trouble for using the wrong gesture or for looking the wrong person in the eye. Did you also know that shaking your head can be interpreted as ‘yes’ in India?

“Hi, would you like to buy some drugs?

– Nervously shakes head –

“Great! Here’s two kilograms of cocaine!”

Kuh-Myoo-Nick-Ashion

Learn a few words and phrases from the local language and the appropriate situations to use them in. You would be surprised at how much a ‘Yallah’ or a ‘Habibi’ can get people to warm up to you in the Middle East. Also, knowing the language makes ordering food that much easier. Just saying.

Who Ya’ Gonna Call?

It’s very useful to have in hand a bunch of contacts that you can get in touch with if-knock on wood- you should ever find yourself in trouble, eg: Your home country’s Embassy/Consulate(stolen passports are a thing in some countries you know?), local emergency numbers etc. If you have friends or relatives in the country/area, make sure you have their numbers as well. There’s no telling what kind of emergency you might encounter on the road.

Link Up With Other Travellers And Locals!

This is for many people, the single greatest reward of solo travel-meeting new people. There’s so much you discover from engaging with people from different cultures and backgrounds. Yes, I’m being captain obvious here, but it’s a point that just had to be reiterated.  Being alive in the internet age has its perks.

A slew of apps and websites have made it that much easier for travelers to get in touch with people at their destinations. It doesn’t matter if you’re just hanging out with your host from ‘AirBnB’ and ‘Couchsurfing’ or finding fellow travelers to share in your adventure from ‘Penroads’, you’re guaranteed to meet some cool people on your journey. As a matter of fact, Penroads is the best way for you to connect with international travellers coming in from all over the world, so it’s definitely a useful tool to have (It’s a shameless plug. I am so sorry. But it really works!).

Stay Healthy!

Last but never the least, take care of your body. Stay hydrated. It’s no good if your mind yells “Onward!” and your body groans “Hell no!”. Find out if you need to get vaccinated before setting off. Carry some basic medicines and bandages if you can, especially if you’re venturing into the wilderness. On occasion you might have to be careful about where and what you eat as well. Talk to someone who has travelled to India and you just might hear the story about how the delicious chicken Tikka from a street vendor gave them a bad case of ‘Delhi Belly’.

Happy tripping!

Parag Murali is the Marketing & Happiness Manager at penroads.com. He combines his love for travelling and people into a daily passion for bringing travellers together. You can contact him at parag@penroads.com for just about anything, so feel free!

 



  • Hiking and Trekking
  • Machu Picchu Inca Trail
  • Tips and Things To Know

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Radical new business model for pharmaceutical industry needed to avert antibiotic resistance crisis

7 October 2015

20151009Antibiotics.jpg

High-level complex of physiologically active antibiotic substance extracted from blastema at the Arctic Innovation Center (AIC) of Ammosov, North-Eastern Federal University (NEFU) in Yakutsk. Photo: Yuri Smityuk/ITAR-TASS Photo/Corbis.

Revenues for pharmaceutical companies need to be 'delinked' from sales of antibiotics to avoid their over-use and avert a public health crisis, says a new report from the think-tank Chatham House.

Over-use of antibiotics is contributing to the growing resistance of potentially deadly bacteria to existing drugs, threatening a public health crisis in the near future. The report notes that, by 2050, failing to tackle antibiotic resistance could result in 10 million premature deaths per year.                                       

Novel antibiotics to combat resistant pathogens are thus desperately needed, but market incentives are exacerbating the problem. Towards a New Global Business Model for Antibiotics: Delinking Revenues from Sales states that,                                       


'The current business model requires high levels of antibiotic use in order to recover the costs of R&D. But mitigating the spread of resistance demands just the opposite: restrictions on the use of antibiotics.'

                                       

To tackle this catch-22 problem, the Centre on Global Health Security at Chatham House recommends the establishment of a global body to implement a radical new business model for the industry, which would encourage investment and promote global access to - and conservation of - antibiotics.      

The current business model has several perverse effects. As R&D is an inherently risky and costly endeavour, the industry is chronically under-investing in new treatments. Today, few large pharmaceutical companies retain active antibacterial drug discovery programmes. Re-stoking the industry's interest in antibiotics would be one of the primary roles of the new body.   

Secondly, the need to recover sunk cost under the current business model encourages both high prices and over-marketing of successful drugs, making potentially life-saving treatments unaffordable to many in developing countries, while simultaneously encouraging over-use in developed markets and increasing resistance.   

The new global body would address these challenges by ‘delinking’ pharmaceutical revenues from sales of antibiotics. It would do this by directly financing the research and development of new drugs, which it would then acquire at a price based on production costs rather than the recovery of R&D expenses. Acquisition could take the form of procurement contracts with companies, the purchase of full IP rights or other licensing mechanisms.                                       

This would enable it to promote global access to antibiotics while simultaneously restricting over-use. Conservation would be promoted through education, regulation and good clinical practice, with the report recommending that 'proven conservation methods such as antibiotic stewardship programmes… be incentivized and implemented immediately.'

Priorities for R&D financing would be based on a comprehensive assessment of  threats arising from resistance. Antibiotics would qualify for the highest level of financial incentives if they combat resistant pathogens posing a serious threat to human health.                                       

Finance for the new body would come from individual nation states, with the report noting that this could 'begin with a core group of countries with significant research activity and large antibiotic markets, (though) it is envisaged that all high income countries should make an appropriate financial contribution.'                                 

It is not yet clear exactly how much funding would be necessary to combat resistance, but with inaction expected to cost $100 trillion in cumulative economic damage, the report argues that 'an additional global investment of up to $3.5 billion a year (about 10 per cent of the current value of global sales of antibiotics) would be a bargain.'

Editor's notes

Towards a New Global Business Model for Antibiotics: Delinking Revenues from Sales, is a Chatham House report edited by Charles Clift, Unni Gopinathan, Chantal Morel, Kevin Outterson, John-Arne Røttingen and Anthony So.

The report is embargoed until 00.01 GMT Friday 9 October.

For more information, or to request an interview with the editors, contact the press office.

Contacts

Press Office

+44 (0)20 7957 5739