ma

Challenging cases in dermatology.

El-Darouti, Mohammad Ali.
9783030218553 (electronic bk.)




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Cellular internet of things : from massive deployments to critical 5G applications

Liberg, Olof, 1943- author.
9780081029039 (electronic bk.)




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Breakfast cereals and how they are made : raw materials, processing, and production

9780128120446 (electronic bk.)




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Biosystematics of Triticeae.

Yen, Chi, author
9789811399312 (electronic bk.)




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Biology and ecology of venomous marine cnidarians

Santhanam, Ramasamy, 1946- author
9789811516030 (electronic bk.)




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Biologic and systemic agents in dermatology

9783319668840 (electronic bk.)




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Biodiversity of the Himalaya : Jammu and Kashmir State

9789813291744 (electronic bk.)




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Binary code fingerprinting for cybersecurity : application to malicious code fingerprinting

Alrabaee, Saed, authior
9783030342388 (electronic bk.)




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Berquist's musculoskeletal imaging companion

Peterson, Jeffrey J., author.
9781496314994




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Atlas of ulcers in systemic sclerosis : diagnosis and management

9783319984773 (electronic bk.)




ma

Atlas of male genital dermatology

Hall, Anthony, author.
9783319997506 (electronic bk.)




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Atlas of Lasers and Lights in Dermatology

Cannarozzo, Giovanni. author.
9783030312329




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Anomalies of the Developing Dentition : a Clinical Guide to Diagnosis and Management

Soxman, Jane A., author.
9783030031640 (electronic bk.)




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Animal agriculture : sustainability, challenges and innovations

9780128170526




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A treatise on topical corticosteroids in dermatology : use, misuse and abuse

9789811046094




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A handbook of nuclear applications in humans' lives

Tabbakh, Farshid, author.
9781527544512 (electronic bk.)




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100 cases in clinical pharmacology, therapeutics and prescribing

Layne, Kerry, author.
9780429624537 electronic book




ma

Fill Management Plan PIC




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InBios receives Emergency Use Authorization for its Smart Detect...

InBios International, Inc. announces the U.S. Food and Drug Administration (FDA) issued an emergency use authorization (EUA) for its diagnostic test that can be used immediately by CLIA...

(PRWeb April 08, 2020)

Read the full story at https://www.prweb.com/releases/inbios_receives_emergency_use_authorization_for_its_smart_detect_sars_cov_2_rrt_pcr_kit_for_detection_of_the_virus_causing_covid_19/prweb17036897.htm





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Penalized generalized empirical likelihood with a diverging number of general estimating equations for censored data

Niansheng Tang, Xiaodong Yan, Xingqiu Zhao.

Source: The Annals of Statistics, Volume 48, Number 1, 607--627.

Abstract:
This article considers simultaneous variable selection and parameter estimation as well as hypothesis testing in censored survival models where a parametric likelihood is not available. For the problem, we utilize certain growing dimensional general estimating equations and propose a penalized generalized empirical likelihood, where the general estimating equations are constructed based on the semiparametric efficiency bound of estimation with given moment conditions. The proposed penalized generalized empirical likelihood estimators enjoy the oracle properties, and the estimator of any fixed dimensional vector of nonzero parameters achieves the semiparametric efficiency bound asymptotically. Furthermore, we show that the penalized generalized empirical likelihood ratio test statistic has an asymptotic central chi-square distribution. The conditions of local and restricted global optimality of weighted penalized generalized empirical likelihood estimators are also discussed. We present a two-layer iterative algorithm for efficient implementation, and investigate its convergence property. The performance of the proposed methods is demonstrated by extensive simulation studies, and a real data example is provided for illustration.




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Markov equivalence of marginalized local independence graphs

Søren Wengel Mogensen, Niels Richard Hansen.

Source: The Annals of Statistics, Volume 48, Number 1, 539--559.

Abstract:
Symmetric independence relations are often studied using graphical representations. Ancestral graphs or acyclic directed mixed graphs with $m$-separation provide classes of symmetric graphical independence models that are closed under marginalization. Asymmetric independence relations appear naturally for multivariate stochastic processes, for instance, in terms of local independence. However, no class of graphs representing such asymmetric independence relations, which is also closed under marginalization, has been developed. We develop the theory of directed mixed graphs with $mu $-separation and show that this provides a graphical independence model class which is closed under marginalization and which generalizes previously considered graphical representations of local independence. Several graphs may encode the same set of independence relations and this means that in many cases only an equivalence class of graphs can be identified from observational data. For statistical applications, it is therefore pivotal to characterize graphs that induce the same independence relations. Our main result is that for directed mixed graphs with $mu $-separation each equivalence class contains a maximal element which can be constructed from the independence relations alone. Moreover, we introduce the directed mixed equivalence graph as the maximal graph with dashed and solid edges. This graph encodes all information about the edges that is identifiable from the independence relations, and furthermore it can be computed efficiently from the maximal graph.




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Optimal prediction in the linearly transformed spiked model

Edgar Dobriban, William Leeb, Amit Singer.

Source: The Annals of Statistics, Volume 48, Number 1, 491--513.

Abstract:
We consider the linearly transformed spiked model , where the observations $Y_{i}$ are noisy linear transforms of unobserved signals of interest $X_{i}$: egin{equation*}Y_{i}=A_{i}X_{i}+varepsilon_{i},end{equation*} for $i=1,ldots ,n$. The transform matrices $A_{i}$ are also observed. We model the unobserved signals (or regression coefficients) $X_{i}$ as vectors lying on an unknown low-dimensional space. Given only $Y_{i}$ and $A_{i}$ how should we predict or recover their values? The naive approach of performing regression for each observation separately is inaccurate due to the large noise level. Instead, we develop optimal methods for predicting $X_{i}$ by “borrowing strength” across the different samples. Our linear empirical Bayes methods scale to large datasets and rely on weak moment assumptions. We show that this model has wide-ranging applications in signal processing, deconvolution, cryo-electron microscopy, and missing data with noise. For missing data, we show in simulations that our methods are more robust to noise and to unequal sampling than well-known matrix completion methods.




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Efficient estimation of linear functionals of principal components

Vladimir Koltchinskii, Matthias Löffler, Richard Nickl.

Source: The Annals of Statistics, Volume 48, Number 1, 464--490.

Abstract:
We study principal component analysis (PCA) for mean zero i.i.d. Gaussian observations $X_{1},dots,X_{n}$ in a separable Hilbert space $mathbb{H}$ with unknown covariance operator $Sigma $. The complexity of the problem is characterized by its effective rank $mathbf{r}(Sigma):=frac{operatorname{tr}(Sigma)}{|Sigma |}$, where $mathrm{tr}(Sigma)$ denotes the trace of $Sigma $ and $|Sigma|$ denotes its operator norm. We develop a method of bias reduction in the problem of estimation of linear functionals of eigenvectors of $Sigma $. Under the assumption that $mathbf{r}(Sigma)=o(n)$, we establish the asymptotic normality and asymptotic properties of the risk of the resulting estimators and prove matching minimax lower bounds, showing their semiparametric optimality.




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Bootstrap confidence regions based on M-estimators under nonstandard conditions

Stephen M. S. Lee, Puyudi Yang.

Source: The Annals of Statistics, Volume 48, Number 1, 274--299.

Abstract:
Suppose that a confidence region is desired for a subvector $ heta $ of a multidimensional parameter $xi =( heta ,psi )$, based on an M-estimator $hat{xi }_{n}=(hat{ heta }_{n},hat{psi }_{n})$ calculated from a random sample of size $n$. Under nonstandard conditions $hat{xi }_{n}$ often converges at a nonregular rate $r_{n}$, in which case consistent estimation of the distribution of $r_{n}(hat{ heta }_{n}- heta )$, a pivot commonly chosen for confidence region construction, is most conveniently effected by the $m$ out of $n$ bootstrap. The above choice of pivot has three drawbacks: (i) the shape of the region is either subjectively prescribed or controlled by a computationally intensive depth function; (ii) the region is not transformation equivariant; (iii) $hat{xi }_{n}$ may not be uniquely defined. To resolve the above difficulties, we propose a one-dimensional pivot derived from the criterion function, and prove that its distribution can be consistently estimated by the $m$ out of $n$ bootstrap, or by a modified version of the perturbation bootstrap. This leads to a new method for constructing confidence regions which are transformation equivariant and have shapes driven solely by the criterion function. A subsampling procedure is proposed for selecting $m$ in practice. Empirical performance of the new method is illustrated with examples drawn from different nonstandard M-estimation settings. Extension of our theory to row-wise independent triangular arrays is also explored.




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Spectral and matrix factorization methods for consistent community detection in multi-layer networks

Subhadeep Paul, Yuguo Chen.

Source: The Annals of Statistics, Volume 48, Number 1, 230--250.

Abstract:
We consider the problem of estimating a consensus community structure by combining information from multiple layers of a multi-layer network using methods based on the spectral clustering or a low-rank matrix factorization. As a general theme, these “intermediate fusion” methods involve obtaining a low column rank matrix by optimizing an objective function and then using the columns of the matrix for clustering. However, the theoretical properties of these methods remain largely unexplored. In the absence of statistical guarantees on the objective functions, it is difficult to determine if the algorithms optimizing the objectives will return good community structures. We investigate the consistency properties of the global optimizer of some of these objective functions under the multi-layer stochastic blockmodel. For this purpose, we derive several new asymptotic results showing consistency of the intermediate fusion techniques along with the spectral clustering of mean adjacency matrix under a high dimensional setup, where the number of nodes, the number of layers and the number of communities of the multi-layer graph grow. Our numerical study shows that the intermediate fusion techniques outperform late fusion methods, namely spectral clustering on aggregate spectral kernel and module allegiance matrix in sparse networks, while they outperform the spectral clustering of mean adjacency matrix in multi-layer networks that contain layers with both homophilic and heterophilic communities.




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Optimal rates for community estimation in the weighted stochastic block model

Min Xu, Varun Jog, Po-Ling Loh.

Source: The Annals of Statistics, Volume 48, Number 1, 183--204.

Abstract:
Community identification in a network is an important problem in fields such as social science, neuroscience and genetics. Over the past decade, stochastic block models (SBMs) have emerged as a popular statistical framework for this problem. However, SBMs have an important limitation in that they are suited only for networks with unweighted edges; in various scientific applications, disregarding the edge weights may result in a loss of valuable information. We study a weighted generalization of the SBM, in which observations are collected in the form of a weighted adjacency matrix and the weight of each edge is generated independently from an unknown probability density determined by the community membership of its endpoints. We characterize the optimal rate of misclustering error of the weighted SBM in terms of the Renyi divergence of order 1/2 between the weight distributions of within-community and between-community edges, substantially generalizing existing results for unweighted SBMs. Furthermore, we present a computationally tractable algorithm based on discretization that achieves the optimal error rate. Our method is adaptive in the sense that the algorithm, without assuming knowledge of the weight densities, performs as well as the best algorithm that knows the weight densities.




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Model assisted variable clustering: Minimax-optimal recovery and algorithms

Florentina Bunea, Christophe Giraud, Xi Luo, Martin Royer, Nicolas Verzelen.

Source: The Annals of Statistics, Volume 48, Number 1, 111--137.

Abstract:
The problem of variable clustering is that of estimating groups of similar components of a $p$-dimensional vector $X=(X_{1},ldots ,X_{p})$ from $n$ independent copies of $X$. There exists a large number of algorithms that return data-dependent groups of variables, but their interpretation is limited to the algorithm that produced them. An alternative is model-based clustering, in which one begins by defining population level clusters relative to a model that embeds notions of similarity. Algorithms tailored to such models yield estimated clusters with a clear statistical interpretation. We take this view here and introduce the class of $G$-block covariance models as a background model for variable clustering. In such models, two variables in a cluster are deemed similar if they have similar associations will all other variables. This can arise, for instance, when groups of variables are noise corrupted versions of the same latent factor. We quantify the difficulty of clustering data generated from a $G$-block covariance model in terms of cluster proximity, measured with respect to two related, but different, cluster separation metrics. We derive minimax cluster separation thresholds, which are the metric values below which no algorithm can recover the model-defined clusters exactly, and show that they are different for the two metrics. We therefore develop two algorithms, COD and PECOK, tailored to $G$-block covariance models, and study their minimax-optimality with respect to each metric. Of independent interest is the fact that the analysis of the PECOK algorithm, which is based on a corrected convex relaxation of the popular $K$-means algorithm, provides the first statistical analysis of such algorithms for variable clustering. Additionally, we compare our methods with another popular clustering method, spectral clustering. Extensive simulation studies, as well as our data analyses, confirm the applicability of our approach.




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Robust sparse covariance estimation by thresholding Tyler’s M-estimator

John Goes, Gilad Lerman, Boaz Nadler.

Source: The Annals of Statistics, Volume 48, Number 1, 86--110.

Abstract:
Estimating a high-dimensional sparse covariance matrix from a limited number of samples is a fundamental task in contemporary data analysis. Most proposals to date, however, are not robust to outliers or heavy tails. Toward bridging this gap, in this work we consider estimating a sparse shape matrix from $n$ samples following a possibly heavy-tailed elliptical distribution. We propose estimators based on thresholding either Tyler’s M-estimator or its regularized variant. We prove that in the joint limit as the dimension $p$ and the sample size $n$ tend to infinity with $p/n ogamma>0$, our estimators are minimax rate optimal. Results on simulated data support our theoretical analysis.




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Sparse SIR: Optimal rates and adaptive estimation

Kai Tan, Lei Shi, Zhou Yu.

Source: The Annals of Statistics, Volume 48, Number 1, 64--85.

Abstract:
Sliced inverse regression (SIR) is an innovative and effective method for sufficient dimension reduction and data visualization. Recently, an impressive range of penalized SIR methods has been proposed to estimate the central subspace in a sparse fashion. Nonetheless, few of them considered the sparse sufficient dimension reduction from a decision-theoretic point of view. To address this issue, we in this paper establish the minimax rates of convergence for estimating the sparse SIR directions under various commonly used loss functions in the literature of sufficient dimension reduction. We also discover the possible trade-off between statistical guarantee and computational performance for sparse SIR. We finally propose an adaptive estimation scheme for sparse SIR which is computationally tractable and rate optimal. Numerical studies are carried out to confirm the theoretical properties of our proposed methods.




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The phase transition for the existence of the maximum likelihood estimate in high-dimensional logistic regression

Emmanuel J. Candès, Pragya Sur.

Source: The Annals of Statistics, Volume 48, Number 1, 27--42.

Abstract:
This paper rigorously establishes that the existence of the maximum likelihood estimate (MLE) in high-dimensional logistic regression models with Gaussian covariates undergoes a sharp “phase transition.” We introduce an explicit boundary curve $h_{mathrm{MLE}}$, parameterized by two scalars measuring the overall magnitude of the unknown sequence of regression coefficients, with the following property: in the limit of large sample sizes $n$ and number of features $p$ proportioned in such a way that $p/n ightarrow kappa $, we show that if the problem is sufficiently high dimensional in the sense that $kappa >h_{mathrm{MLE}}$, then the MLE does not exist with probability one. Conversely, if $kappa <h_{mathrm{MLE}}$, the MLE asymptotically exists with probability one.




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Detecting relevant changes in the mean of nonstationary processes—A mass excess approach

Holger Dette, Weichi Wu.

Source: The Annals of Statistics, Volume 47, Number 6, 3578--3608.

Abstract:
This paper considers the problem of testing if a sequence of means $(mu_{t})_{t=1,ldots ,n}$ of a nonstationary time series $(X_{t})_{t=1,ldots ,n}$ is stable in the sense that the difference of the means $mu_{1}$ and $mu_{t}$ between the initial time $t=1$ and any other time is smaller than a given threshold, that is $|mu_{1}-mu_{t}|leq c$ for all $t=1,ldots ,n$. A test for hypotheses of this type is developed using a bias corrected monotone rearranged local linear estimator and asymptotic normality of the corresponding test statistic is established. As the asymptotic variance depends on the location of the roots of the equation $|mu_{1}-mu_{t}|=c$ a new bootstrap procedure is proposed to obtain critical values and its consistency is established. As a consequence we are able to quantitatively describe relevant deviations of a nonstationary sequence from its initial value. The results are illustrated by means of a simulation study and by analyzing data examples.




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Intrinsic Riemannian functional data analysis

Zhenhua Lin, Fang Yao.

Source: The Annals of Statistics, Volume 47, Number 6, 3533--3577.

Abstract:
In this work we develop a novel and foundational framework for analyzing general Riemannian functional data, in particular a new development of tensor Hilbert spaces along curves on a manifold. Such spaces enable us to derive Karhunen–Loève expansion for Riemannian random processes. This framework also features an approach to compare objects from different tensor Hilbert spaces, which paves the way for asymptotic analysis in Riemannian functional data analysis. Built upon intrinsic geometric concepts such as vector field, Levi-Civita connection and parallel transport on Riemannian manifolds, the developed framework applies to not only Euclidean submanifolds but also manifolds without a natural ambient space. As applications of this framework, we develop intrinsic Riemannian functional principal component analysis (iRFPCA) and intrinsic Riemannian functional linear regression (iRFLR) that are distinct from their traditional and ambient counterparts. We also provide estimation procedures for iRFPCA and iRFLR, and investigate their asymptotic properties within the intrinsic geometry. Numerical performance is illustrated by simulated and real examples.




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Joint convergence of sample autocovariance matrices when &#36;p/n o 0&#36; with application

Monika Bhattacharjee, Arup Bose.

Source: The Annals of Statistics, Volume 47, Number 6, 3470--3503.

Abstract:
Consider a high-dimensional linear time series model where the dimension $p$ and the sample size $n$ grow in such a way that $p/n o 0$. Let $hat{Gamma }_{u}$ be the $u$th order sample autocovariance matrix. We first show that the LSD of any symmetric polynomial in ${hat{Gamma }_{u},hat{Gamma }_{u}^{*},ugeq 0}$ exists under independence and moment assumptions on the driving sequence together with weak assumptions on the coefficient matrices. This LSD result, with some additional effort, implies the asymptotic normality of the trace of any polynomial in ${hat{Gamma }_{u},hat{Gamma }_{u}^{*},ugeq 0}$. We also study similar results for several independent MA processes. We show applications of the above results to statistical inference problems such as in estimation of the unknown order of a high-dimensional MA process and in graphical and significance tests for hypotheses on coefficient matrices of one or several such independent processes.




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Minimax posterior convergence rates and model selection consistency in high-dimensional DAG models based on sparse Cholesky factors

Kyoungjae Lee, Jaeyong Lee, Lizhen Lin.

Source: The Annals of Statistics, Volume 47, Number 6, 3413--3437.

Abstract:
In this paper we study the high-dimensional sparse directed acyclic graph (DAG) models under the empirical sparse Cholesky prior. Among our results, strong model selection consistency or graph selection consistency is obtained under more general conditions than those in the existing literature. Compared to Cao, Khare and Ghosh [ Ann. Statist. (2019) 47 319–348], the required conditions are weakened in terms of the dimensionality, sparsity and lower bound of the nonzero elements in the Cholesky factor. Furthermore, our result does not require the irrepresentable condition, which is necessary for Lasso-type methods. We also derive the posterior convergence rates for precision matrices and Cholesky factors with respect to various matrix norms. The obtained posterior convergence rates are the fastest among those of the existing Bayesian approaches. In particular, we prove that our posterior convergence rates for Cholesky factors are the minimax or at least nearly minimax depending on the relative size of true sparseness for the entire dimension. The simulation study confirms that the proposed method outperforms the competing methods.




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A smeary central limit theorem for manifolds with application to high-dimensional spheres

Benjamin Eltzner, Stephan F. Huckemann.

Source: The Annals of Statistics, Volume 47, Number 6, 3360--3381.

Abstract:
The (CLT) central limit theorems for generalized Fréchet means (data descriptors assuming values in manifolds, such as intrinsic means, geodesics, etc.) on manifolds from the literature are only valid if a certain empirical process of Hessians of the Fréchet function converges suitably, as in the proof of the prototypical BP-CLT [ Ann. Statist. 33 (2005) 1225–1259]. This is not valid in many realistic scenarios and we provide for a new very general CLT. In particular, this includes scenarios where, in a suitable chart, the sample mean fluctuates asymptotically at a scale $n^{alpha }$ with exponents $alpha <1/2$ with a nonnormal distribution. As the BP-CLT yields only fluctuations that are, rescaled with $n^{1/2}$, asymptotically normal, just as the classical CLT for random vectors, these lower rates, somewhat loosely called smeariness, had to date been observed only on the circle. We make the concept of smeariness on manifolds precise, give an example for two-smeariness on spheres of arbitrary dimension, and show that smeariness, although “almost never” occurring, may have serious statistical implications on a continuum of sample scenarios nearby. In fact, this effect increases with dimension, striking in particular in high dimension low sample size scenarios.




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On optimal designs for nonregular models

Yi Lin, Ryan Martin, Min Yang.

Source: The Annals of Statistics, Volume 47, Number 6, 3335--3359.

Abstract:
Classically, Fisher information is the relevant object in defining optimal experimental designs. However, for models that lack certain regularity, the Fisher information does not exist, and hence, there is no notion of design optimality available in the literature. This article seeks to fill the gap by proposing a so-called Hellinger information , which generalizes Fisher information in the sense that the two measures agree in regular problems, but the former also exists for certain types of nonregular problems. We derive a Hellinger information inequality, showing that Hellinger information defines a lower bound on the local minimax risk of estimators. This provides a connection between features of the underlying model—in particular, the design—and the performance of estimators, motivating the use of this new Hellinger information for nonregular optimal design problems. Hellinger optimal designs are derived for several nonregular regression problems, with numerical results empirically demonstrating the efficiency of these designs compared to alternatives.




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Hypothesis testing on linear structures of high-dimensional covariance matrix

Shurong Zheng, Zhao Chen, Hengjian Cui, Runze Li.

Source: The Annals of Statistics, Volume 47, Number 6, 3300--3334.

Abstract:
This paper is concerned with test of significance on high-dimensional covariance structures, and aims to develop a unified framework for testing commonly used linear covariance structures. We first construct a consistent estimator for parameters involved in the linear covariance structure, and then develop two tests for the linear covariance structures based on entropy loss and quadratic loss used for covariance matrix estimation. To study the asymptotic properties of the proposed tests, we study related high-dimensional random matrix theory, and establish several highly useful asymptotic results. With the aid of these asymptotic results, we derive the limiting distributions of these two tests under the null and alternative hypotheses. We further show that the quadratic loss based test is asymptotically unbiased. We conduct Monte Carlo simulation study to examine the finite sample performance of the two tests. Our simulation results show that the limiting null distributions approximate their null distributions quite well, and the corresponding asymptotic critical values keep Type I error rate very well. Our numerical comparison implies that the proposed tests outperform existing ones in terms of controlling Type I error rate and power. Our simulation indicates that the test based on quadratic loss seems to have better power than the test based on entropy loss.




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Sampling and estimation for (sparse) exchangeable graphs

Victor Veitch, Daniel M. Roy.

Source: The Annals of Statistics, Volume 47, Number 6, 3274--3299.

Abstract:
Sparse exchangeable graphs on $mathbb{R}_{+}$, and the associated graphex framework for sparse graphs, generalize exchangeable graphs on $mathbb{N}$, and the associated graphon framework for dense graphs. We develop the graphex framework as a tool for statistical network analysis by identifying the sampling scheme that is naturally associated with the models of the framework, formalizing two natural notions of consistent estimation of the parameter (the graphex) underlying these models, and identifying general consistent estimators in each case. The sampling scheme is a modification of independent vertex sampling that throws away vertices that are isolated in the sampled subgraph. The estimators are variants of the empirical graphon estimator, which is known to be a consistent estimator for the distribution of dense exchangeable graphs; both can be understood as graph analogues to the empirical distribution in the i.i.d. sequence setting. Our results may be viewed as a generalization of consistent estimation via the empirical graphon from the dense graph regime to also include sparse graphs.




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On partial-sum processes of ARMAX residuals

Steffen Grønneberg, Benjamin Holcblat.

Source: The Annals of Statistics, Volume 47, Number 6, 3216--3243.

Abstract:
We establish general and versatile results regarding the limit behavior of the partial-sum process of ARMAX residuals. Illustrations include ARMA with seasonal dummies, misspecified ARMAX models with autocorrelated errors, nonlinear ARMAX models, ARMA with a structural break, a wide range of ARMAX models with infinite-variance errors, weak GARCH models and the consistency of kernel estimation of the density of ARMAX errors. Our results identify the limit distributions, and provide a general algorithm to obtain pivot statistics for CUSUM tests.




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Adaptive estimation of the rank of the coefficient matrix in high-dimensional multivariate response regression models

Xin Bing, Marten H. Wegkamp.

Source: The Annals of Statistics, Volume 47, Number 6, 3157--3184.

Abstract:
We consider the multivariate response regression problem with a regression coefficient matrix of low, unknown rank. In this setting, we analyze a new criterion for selecting the optimal reduced rank. This criterion differs notably from the one proposed in Bunea, She and Wegkamp ( Ann. Statist. 39 (2011) 1282–1309) in that it does not require estimation of the unknown variance of the noise, nor does it depend on a delicate choice of a tuning parameter. We develop an iterative, fully data-driven procedure, that adapts to the optimal signal-to-noise ratio. This procedure finds the true rank in a few steps with overwhelming probability. At each step, our estimate increases, while at the same time it does not exceed the true rank. Our finite sample results hold for any sample size and any dimension, even when the number of responses and of covariates grow much faster than the number of observations. We perform an extensive simulation study that confirms our theoretical findings. The new method performs better and is more stable than the procedure of Bunea, She and Wegkamp ( Ann. Statist. 39 (2011) 1282–1309) in both low- and high-dimensional settings.




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Distributed estimation of principal eigenspaces

Jianqing Fan, Dong Wang, Kaizheng Wang, Ziwei Zhu.

Source: The Annals of Statistics, Volume 47, Number 6, 3009--3031.

Abstract:
Principal component analysis (PCA) is fundamental to statistical machine learning. It extracts latent principal factors that contribute to the most variation of the data. When data are stored across multiple machines, however, communication cost can prohibit the computation of PCA in a central location and distributed algorithms for PCA are thus needed. This paper proposes and studies a distributed PCA algorithm: each node machine computes the top $K$ eigenvectors and transmits them to the central server; the central server then aggregates the information from all the node machines and conducts a PCA based on the aggregated information. We investigate the bias and variance for the resulting distributed estimator of the top $K$ eigenvectors. In particular, we show that for distributions with symmetric innovation, the empirical top eigenspaces are unbiased, and hence the distributed PCA is “unbiased.” We derive the rate of convergence for distributed PCA estimators, which depends explicitly on the effective rank of covariance, eigengap, and the number of machines. We show that when the number of machines is not unreasonably large, the distributed PCA performs as well as the whole sample PCA, even without full access of whole data. The theoretical results are verified by an extensive simulation study. We also extend our analysis to the heterogeneous case where the population covariance matrices are different across local machines but share similar top eigenstructures.




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Projected spline estimation of the nonparametric function in high-dimensional partially linear models for massive data

Heng Lian, Kaifeng Zhao, Shaogao Lv.

Source: The Annals of Statistics, Volume 47, Number 5, 2922--2949.

Abstract:
In this paper, we consider the local asymptotics of the nonparametric function in a partially linear model, within the framework of the divide-and-conquer estimation. Unlike the fixed-dimensional setting in which the parametric part does not affect the nonparametric part, the high-dimensional setting makes the issue more complicated. In particular, when a sparsity-inducing penalty such as lasso is used to make the estimation of the linear part feasible, the bias introduced will propagate to the nonparametric part. We propose a novel approach for estimation of the nonparametric function and establish the local asymptotics of the estimator. The result is useful for massive data with possibly different linear coefficients in each subpopulation but common nonparametric function. Some numerical illustrations are also presented.




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Test for high-dimensional correlation matrices

Shurong Zheng, Guanghui Cheng, Jianhua Guo, Hongtu Zhu.

Source: The Annals of Statistics, Volume 47, Number 5, 2887--2921.

Abstract:
Testing correlation structures has attracted extensive attention in the literature due to both its importance in real applications and several major theoretical challenges. The aim of this paper is to develop a general framework of testing correlation structures for the one , two and multiple sample testing problems under a high-dimensional setting when both the sample size and data dimension go to infinity. Our test statistics are designed to deal with both the dense and sparse alternatives. We systematically investigate the asymptotic null distribution, power function and unbiasedness of each test statistic. Theoretically, we make great efforts to deal with the nonindependency of all random matrices of the sample correlation matrices. We use simulation studies and real data analysis to illustrate the versatility and practicability of our test statistics.




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Eigenvalue distributions of variance components estimators in high-dimensional random effects models

Zhou Fan, Iain M. Johnstone.

Source: The Annals of Statistics, Volume 47, Number 5, 2855--2886.

Abstract:
We study the spectra of MANOVA estimators for variance component covariance matrices in multivariate random effects models. When the dimensionality of the observations is large and comparable to the number of realizations of each random effect, we show that the empirical spectra of such estimators are well approximated by deterministic laws. The Stieltjes transforms of these laws are characterized by systems of fixed-point equations, which are numerically solvable by a simple iterative procedure. Our proof uses operator-valued free probability theory, and we establish a general asymptotic freeness result for families of rectangular orthogonally invariant random matrices, which is of independent interest. Our work is motivated in part by the estimation of components of covariance between multiple phenotypic traits in quantitative genetics, and we specialize our results to common experimental designs that arise in this application.




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Exact lower bounds for the agnostic probably-approximately-correct (PAC) machine learning model

Aryeh Kontorovich, Iosif Pinelis.

Source: The Annals of Statistics, Volume 47, Number 5, 2822--2854.

Abstract:
We provide an exact nonasymptotic lower bound on the minimax expected excess risk (EER) in the agnostic probably-approximately-correct (PAC) machine learning classification model and identify minimax learning algorithms as certain maximally symmetric and minimally randomized “voting” procedures. Based on this result, an exact asymptotic lower bound on the minimax EER is provided. This bound is of the simple form $c_{infty}/sqrt{ u}$ as $ u oinfty$, where $c_{infty}=0.16997dots$ is a universal constant, $ u=m/d$, $m$ is the size of the training sample and $d$ is the Vapnik–Chervonenkis dimension of the hypothesis class. It is shown that the differences between these asymptotic and nonasymptotic bounds, as well as the differences between these two bounds and the maximum EER of any learning algorithms that minimize the empirical risk, are asymptotically negligible, and all these differences are due to ties in the mentioned “voting” procedures. A few easy to compute nonasymptotic lower bounds on the minimax EER are also obtained, which are shown to be close to the exact asymptotic lower bound $c_{infty}/sqrt{ u}$ even for rather small values of the ratio $ u=m/d$. As an application of these results, we substantially improve existing lower bounds on the tail probability of the excess risk. Among the tools used are Bayes estimation and apparently new identities and inequalities for binomial distributions.




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Phase transition in the spiked random tensor with Rademacher prior

Wei-Kuo Chen.

Source: The Annals of Statistics, Volume 47, Number 5, 2734--2756.

Abstract:
We consider the problem of detecting a deformation from a symmetric Gaussian random $p$-tensor $(pgeq3)$ with a rank-one spike sampled from the Rademacher prior. Recently, in Lesieur et al. (Barbier, Krzakala, Macris, Miolane and Zdeborová (2017)), it was proved that there exists a critical threshold $eta_{p}$ so that when the signal-to-noise ratio exceeds $eta_{p}$, one can distinguish the spiked and unspiked tensors and weakly recover the prior via the minimal mean-square-error method. On the other side, Perry, Wein and Bandeira (Perry, Wein and Bandeira (2017)) proved that there exists a $eta_{p}'<eta_{p}$ such that any statistical hypothesis test cannot distinguish these two tensors, in the sense that their total variation distance asymptotically vanishes, when the signa-to-noise ratio is less than $eta_{p}'$. In this work, we show that $eta_{p}$ is indeed the critical threshold that strictly separates the distinguishability and indistinguishability between the two tensors under the total variation distance. Our approach is based on a subtle analysis of the high temperature behavior of the pure $p$-spin model with Ising spin, arising initially from the field of spin glasses. In particular, we identify the signal-to-noise criticality $eta_{p}$ as the critical temperature, distinguishing the high and low temperature behavior, of the Ising pure $p$-spin mean-field spin glass model.




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The middle-scale asymptotics of Wishart matrices

Didier Chételat, Martin T. Wells.

Source: The Annals of Statistics, Volume 47, Number 5, 2639--2670.

Abstract:
We study the behavior of a real $p$-dimensional Wishart random matrix with $n$ degrees of freedom when $n,p ightarrowinfty$ but $p/n ightarrow0$. We establish the existence of phase transitions when $p$ grows at the order $n^{(K+1)/(K+3)}$ for every $Kinmathbb{N}$, and derive expressions for approximating densities between every two phase transitions. To do this, we make use of a novel tool we call the $mathcal{F}$-conjugate of an absolutely continuous distribution, which is obtained from the Fourier transform of the square root of its density. In the case of the normalized Wishart distribution, this represents an extension of the $t$-distribution to the space of real symmetric matrices.




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Semiparametrically point-optimal hybrid rank tests for unit roots

Bo Zhou, Ramon van den Akker, Bas J. M. Werker.

Source: The Annals of Statistics, Volume 47, Number 5, 2601--2638.

Abstract:
We propose a new class of unit root tests that exploits invariance properties in the Locally Asymptotically Brownian Functional limit experiment associated to the unit root model. The invariance structures naturally suggest tests that are based on the ranks of the increments of the observations, their average and an assumed reference density for the innovations. The tests are semiparametric in the sense that they are valid, that is, have the correct (asymptotic) size, irrespective of the true innovation density. For a correctly specified reference density, our test is point-optimal and nearly efficient. For arbitrary reference densities, we establish a Chernoff–Savage-type result, that is, our test performs as well as commonly used tests under Gaussian innovations but has improved power under other, for example, fat-tailed or skewed, innovation distributions. To avoid nonparametric estimation, we propose a simplified version of our test that exhibits the same asymptotic properties, except for the Chernoff–Savage result that we are only able to demonstrate by means of simulations.




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Doubly penalized estimation in additive regression with high-dimensional data

Zhiqiang Tan, Cun-Hui Zhang.

Source: The Annals of Statistics, Volume 47, Number 5, 2567--2600.

Abstract:
Additive regression provides an extension of linear regression by modeling the signal of a response as a sum of functions of covariates of relatively low complexity. We study penalized estimation in high-dimensional nonparametric additive regression where functional semi-norms are used to induce smoothness of component functions and the empirical $L_{2}$ norm is used to induce sparsity. The functional semi-norms can be of Sobolev or bounded variation types and are allowed to be different amongst individual component functions. We establish oracle inequalities for the predictive performance of such methods under three simple technical conditions: a sub-Gaussian condition on the noise, a compatibility condition on the design and the functional classes under consideration and an entropy condition on the functional classes. For random designs, the sample compatibility condition can be replaced by its population version under an additional condition to ensure suitable convergence of empirical norms. In homogeneous settings where the complexities of the component functions are of the same order, our results provide a spectrum of minimax convergence rates, from the so-called slow rate without requiring the compatibility condition to the fast rate under the hard sparsity or certain $L_{q}$ sparsity to allow many small components in the true regression function. These results significantly broaden and sharpen existing ones in the literature.