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Diphenyl Diselenide Protects Caenorhabditis elegans Model for Huntington's Disease by Activation of Antioxidant Pathway and Decrease in Protein Aggregation

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00074D, Paper
Fabiane Bicca Obetine Baptista, Marina Lopes Machado, Aline da Silva Franzen, Larissa Marafiga Cordeiro, Tassia da Silveira, Leticia Arantes, Félix A. A. Soares
Huntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease with a distinct phenotype. It occurs due to a mutation in huntingtin (or IT19) gene with abnormal CAG repeat, leading...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The study of levels from redox-active elements in cerebrospinal fluid of amyotrophic lateral sclerosis patients carrying disease-related gene mutations shows potential copper dyshomeostasis

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00051E, Paper
Federica Violi, Nikolay Solovyev, Marco Vinceti, Jessica Mandrioli, Marianna Lucio, Bernhard Michalke
Gene-environment interaction is as a possible key factor in the development of ALS. The levels of redox species of Cu, Fe, and Mn were assessed in cerebrospinal fluid, showing a possible positive association between Cu and genetic ALS.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Evidence that levels of nine essential metals in post-mortem human-Alzheimer's-brain and ex vivo rat-brain tissues are unaffected by differences in post-mortem delay, age, disease staging, and brain bank location

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00048E, Paper
Melissa Scholefield, Stephanie J. Church, Jingshu Xu, Sarah Kassab, Natalie J. Gardiner, Federico Roncaroli, Nigel M. Hooper, Richard D. Unwin, Garth J. S. Cooper
Metal findings in human Alzheimer brains are consistent despite differences in sample post-mortem delay, age, Braak stage and biobank location.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Reacher Said Nothing: Lee Child and the Making of Make Me


 
It had never been attempted before, and might never be done again. One man watching another man write a novel from beginning to end.
 
On September 1, 2014, in an 11th floor apartment in New York, Lee Child embarked on the twentieth book in his globally successful Jack Reacher series. Andy Martin was there to see him do it, sitting a couple of yards behind him, peering over his shoulder as the writer took another drag of a Camel cigarette and tapped

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Reacher Said Nothing: Lee Child and the Making of Make Me


 
It had never been attempted before, and might never be done again. One man watching another man write a novel from beginning to end.
 
On September 1, 2014, in an 11th floor apartment in New York, Lee Child embarked on the twentieth book in his globally successful Jack Reacher series. Andy Martin was there to see him do it, sitting a couple of yards behind him, peering over his shoulder as the writer took another drag of a Camel cigarette and tapped

Read More...




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Bodies merged, new guidelines implemented

Bodies merged, new guidelines implemented




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TSE proprietor extends helping hand to widows, differently abled persons

TSE proprietor extends helping hand to widows, differently abled persons




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Dr S Ranjan provides relief material again

Dr S Ranjan provides relief material again




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Kangpokpi asks passenger vehicles not to stop midway

Kangpokpi asks passenger vehicles not to stop midway




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[ASAP] In Vitro Identification of the Hamiltonian Cycle Using a Circular Structure Assisted DNA Computer

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00150




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[ASAP] Ce(OTf)<sub>3</sub>-Catalyzed Multicomponent Reaction of Alkynyl Carboxylic Acids, <italic toggle="yes">tert</italic>-Butyl Isocyanide, and Azides for the Assembly of Triazole–Oxazole Derivatives

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00012




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[ASAP] Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00001




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Annual Report to the Nation: Overall cancer mortality continues to decline; Special section on adults ages 20 to 49 shows higher cancer incidence and mortality for women than men

The 2019 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline and cancer incidence dropped in men and remained stable in women. A special section reports on recent cancer trends in younger adults.




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NCI study finds long-term increased risk of cancer death following common treatment for hyperthyroidism

Findings from a new NCI study of patients who received radioactive iodine (RAI) treatment for hyperthyroidism show an association between the dose of treatment and long-term risk of death from solid cancers, including breast cancer.




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In NIH trial, selumetinib shrinks tumors, provides clinical benefit for children with NF1

An NCI clinical trial finds the drug selumetinib improves outcomes for children with neurofibromatosis type 1 (NF1), shrinking inoperable tumors called plexiform neurofibromas, reducing pain, and improving function and overall quality of life.




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NCI study provides genetic insights into osteosarcoma in children

A new study offers insight into genetic alterations associated with osteosarcoma, the most common bone tumor of children and adolescents, and the findings have implications for genetic testing of children with osteosarcoma and their families.




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NCI statement on clinical trials during COVID-19 pandemic

Statement from the National Cancer Institute providing information regarding treatment of cancer patients and participation in clinical trials during the COVID-19 pandemic.




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Manyjilyjarra - English pictorial dictionary of landscape terms / [prepared for Kanyirninpa Jukurrpa by Clair Hill and Andrew Turk with assistance from Martu language speakers: Gladys Bidu; Jakayu Biljabu; Nancy Chapman; Mulyatingki Marney; Minyawu Miller




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Meng Yuan di guo chu qi de zheng jiao guan xi / Hu Qide zhu

Hu, Qide




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Chun qiu fan lu / Zhang Shiliang, Zhong Zhaopeng, Zhou Guidian yi zhu




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Ren kou dao gua di qu she hui guan li yan jiu = A study of public administration in areas where migrant residents outnumber permanent residents / Jin Sanlin zhu

Jin, Sanlin




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Cheng xiang gong ping shi yu xia de dang dai Zhongguo hu ji zhi du yan jiu = Chengxiang gongping shiyuxia de dangdai Zhongguo huji zhidu yanjiu / Bie Hongxuan zhu

Bie, Hongxuan, author




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Di fang wen hua yu xin yang gong tong ti de sheng cheng : ren lei xue yu Zhongguo Jidu jiao yan jiu / Huang Jianbo zhu

Huang, Jianbo, author




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Zhongguo xin xing cheng zhen hua jian she yan jiu = Zhongguo xinxing chengzhenhua jianshe yanjiu / zhu bian Zhang Zhanbin, Zhang Xiaode, Fan Jida




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Hetaria : Axis powers 2 / Himaruya Hidekazu

Himaruya, Hidekazu




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Hetaria : Axis powers / Himaruya Hidekazu

Himaruya, Hidekazu




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Tanomoshiki Nihongo / Kawasaki Bura, Yoshida Sensha

Kawasaki, Bura, 1963-




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Price of inequality : how today's divided society endangers our future. Chinese

Stiglitz, Joseph E




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[ASAP] Carbene-Catalyzed a,?-Deuteration of Enals under Oxidative Conditions

ACS Catalysis
DOI: 10.1021/acscatal.0c00636




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[ASAP] Fe Single-Atom Catalyst for Visible-Light-Driven Photofixation of Nitrogen Sensitized by Triphenylphosphine and Sodium Iodide

ACS Catalysis
DOI: 10.1021/acscatal.0c00920




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[ASAP] Positive Effects of H<sub>2</sub>O on the Hydrogen Oxidation Reaction on Sr<sub>2</sub>Fe<sub>1.5</sub>Mo<sub>0.5</sub>O<sub>6-d</sub>-Based Perovskite Anodes for Solid Oxide Fuel Cells

ACS Catalysis
DOI: 10.1021/acscatal.9b05458




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[ASAP] Electrostatically Driven Multielectron Transfer for the Photocatalytic Regeneration of Nicotinamide Cofactor

ACS Catalysis
DOI: 10.1021/acscatal.0c01478




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[ASAP] Tuning the Metal–Support Interaction and Enhancing the Stability of Titania-Supported Cobalt Fischer–Tropsch Catalysts via Carbon Nitride Coating

ACS Catalysis
DOI: 10.1021/acscatal.0c01121




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[ASAP] Selective Room-Temperature Hydrogenation of Amides to Amines and Alcohols Catalyzed by a Ruthenium Pincer Complex and Mechanistic Insight

ACS Catalysis
DOI: 10.1021/acscatal.0c01406




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[ASAP] The Energetics of Hydrogen Molecule Oxidation in NiFe-hydrogenase

ACS Catalysis
DOI: 10.1021/acscatal.0c00396




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[ASAP] Toward the Atomic Scale Simulation of Intricate Acidic Aluminosilicate Catalysts

ACS Catalysis
DOI: 10.1021/acscatal.0c01136




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[ASAP] A Mechanistic Rationale Approach Revealed the Unexpected Chemoselectivity of an Artificial Ru-Dependent Oxidase: A Dual Experimental/Theoretical Approach

ACS Catalysis
DOI: 10.1021/acscatal.9b04904




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[ASAP] Heterolytic Hydrogen Activation: Understanding Support Effects in Water–Gas Shift, Hydrodeoxygenation, and CO Oxidation Catalysis

ACS Catalysis
DOI: 10.1021/acscatal.0c01059




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[ASAP] Au/Pb Interface Allows the Methane Formation Pathway in Carbon Dioxide Electroreduction

ACS Catalysis
DOI: 10.1021/acscatal.0c00749




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[ASAP] Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes

ACS Catalysis
DOI: 10.1021/acscatal.0c01103




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[ASAP] Role of Water on the Structure of Palladium for Complete Oxidation of Methane

ACS Catalysis
DOI: 10.1021/acscatal.0c01069




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[ASAP] Modulating Location of Single Copper Atoms in Polymeric Carbon Nitride for Enhanced Photoredox Catalysis

ACS Catalysis
DOI: 10.1021/acscatal.0c01099




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[ASAP] Regioselective Cross-Electrophile Coupling of Epoxides and (Hetero)aryl Iodides via Ni/Ti/Photoredox Catalysis

ACS Catalysis
DOI: 10.1021/acscatal.0c01199




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[ASAP] Photocatalytic Deoxygenation of Sulfoxides Using Visible Light: Mechanistic Investigations and Synthetic Applications

ACS Catalysis
DOI: 10.1021/acscatal.0c00690




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[ASAP] Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease

ACS Catalysis
DOI: 10.1021/acscatal.0c00110




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[ASAP] Gold(I)-Catalyzed Highly Enantioselective [4 + 2]-Annulations of Cyclopentadienes with Nitrosoarenes via Nitroso-Povarov versus Oxidative Nitroso-Povarov Reactions

ACS Catalysis
DOI: 10.1021/acscatal.0c01293




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[ASAP] Isolated Pd Sites as Selective Catalysts for Electrochemical and Direct Hydrogen Peroxide Synthesis

ACS Catalysis
DOI: 10.1021/acscatal.0c01305




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[ASAP] Development of Ketone-Based Brominating Agents (KBA) for the Practical Asymmetric a-Bromination of Aldehydes Catalyzed by Tritylpyrrolidine

ACS Catalysis
DOI: 10.1021/acscatal.0c01596




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Data | Sudden spike in cases results in fastest COVID-19 doubling rate in Punjab in the past week

The State has a low testing rate relative to India's avg despite cases doubling quickly in the last week




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Kerala Institute says it has a faster and cheaper test for COVID-19

A Kerala-based institute has developed a diagnostic test for Covid-19 which it claims can furnish results in less than half the time taken by the method currently being used in the country and for a fraction of its cost — ₹1,000.