This Mexico City taquero serves tacos and tortas sure to satisfy soccer stars. Most gym-goers have a favorite post-workout meal. Some swear by chocolate milk with its blend of sugar, protein, and fat, while others swear by cottage cheese, oatmeal, or smoothies.…

The 10th restaurant from Bay Area restaurateur Hoyul Steven Choi offers a creative take on Korean-infused cuisine. You'd think that after opening nearly a dozen successful restaurants in the ultra-competitive Bay Area dining scene, restaurateur Hoyul Steven Choi would have calmed his new restaurant jitters by now. But Choi says that's not the case.…

Provided herein are methods of reliably determining whether or not an individual is a user of tobacco.

Disclosed are methods and compositions for detecting the presence of a cancer in a subject and assessing the efficacy of treatments for the same. The disclosed method use reverse transcription polymerase chain reaction (RT-PCR) and multiplex polymerase chain reaction techniques as well as Template Exchange Extension Reaction (TEER) to detect the presence of point mutations, truncations, or fusions of anaplastic lymphoma kinase.

The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.

Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.

In flow cytometry, particles (2) can be distinguished between populations (8) by combining n-dimensional parameter data, which may be derived from signal data from a particle, to mathematically achieve numerical results representative of an alteration (48). An alteration may include a rotational alteration, a scaled alteration, or perhaps even a translational alteration. Alterations may enhance separation of data points which may provide real-time classification (49) of signal data corresponding to individual particles into one of at least two populations.

Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include contacting a biological sample having cells with an assay reagent that includes one or more analyte-specific binding members to produce a biological sample assay composition and introducing the biological assay composition into an inlet of a flow cytometer having an integrated acoustic separator. Systems, including a flow cytometer with integrated acoustic separator having one or more acoustic concentrator devices suitable for practicing the subject methods are also described.

An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.

Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease.

The present invention provides assays for detecting and measuring the presence or level of anti-TNFα drug therapeutics and autoantibodies in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNFα drug therapeutics to detect the presence or level of autoantibodies (e.g., HACA and/or HAHA) against the drug.

The present invention relates to in vitro methods of assessing the susceptibility or responsiveness of a subject to the treatment with an epidermal growth factor receptor (EGFR) inhibitor/antagonist, wherein the subject has been diagnosed or suspected of suffering from inflammation-associated. These methods comprise determining the level of expression of EGFR in myeloid cells in a sample from the subject, wherein an expression of EGFR in the myeloid cells is indicative of the subject being susceptible to the treatment with an EGFR inhibitor/antagonist. The invention also relates to EGFR inhibitors/antagonists for use in the treatment or amelioration of inflammation-associated cancer. The invention furthermore provides in vitro methods of prognosing the survival time, progression-free survival time or disease course of a subject that has been diagnosed or suspected of suffering from from inflammation-associated cancer. In addition thereto, the invention relates to in vitro diagnostic methods of assessing the proneness of a subject to develop inflammation-associated cancer in which the expression of EGFR is determined in myeloid cells from the subject.

The present invention relates to an in vitro method of diagnosing chronic myelomonocytic leukemia (CMML) in a subject, said method comprising the steps of: a) Detecting a monocyte population in a biological sample from said subject; b) Quantifying the CD14+/CD16− monocytes in said biological sample; c) Comparing the value of step b) to a reference value; and d) Diagnosing CMML based on said comparison. Preferably, said detecting step a) is performed by an exclusion gating strategy by flow cytometry.

The diagnosis of male infertility is based predominantly on the results of standard semen analysis for concentration, total motility, progressive motility, volume, pH, viscosity and/or morphology. When sperm enter the female reproductive tract, they must undergo a series of physiological changes, known as capacitation, in order to fertilize an egg. This process involves plasma membrane changes that occur in response to stimuli within the female tract. These changes include removal of sterols and redistribution of the ganglioside GM1. Semen analysis identifies only half the cases of male infertility due to standard semen analysis providing little information on sperm functional competence. Previous data demonstrated that localization of the ganglioside, GM1, identifies sub-populations of sperm capable of undergoing the functional maturation process known as capacitation and tracks strongly with fertility.

Compositions and methods useful for point of care testing for hemophilia by measuring coagulation factor levels are provided.

Oakland's alaMar Kitchen & Bar is about to start serving 1,500 free meals per week to restaurant workers who have been displaced and derailed by the coronavirus outbreak.

Located at 100 Grand Ave., chef Nelson German's popular seafood restaurant has just issued this announcement:

"We are here for you, Oakland! ...…

Off the Grid will stage a two-part free-meal giveaway today, April 8, from 12 noon to 1 p.m. at Nob Hill Foods Alameda and from 2:30 p.m. to 3:30 p.m. at Pak 'N Save Emeryville.

It's part of the Grocery Employees Meal Fund, which OTG recently launched to help creators feed grocery-store employees and their family members throughout the Covd-19 crisis.…

East Bay resident Miles Woodruff, CEO of the pioneering vegan-seafood brand Sophie's Kitchen, has just donated 3,000 cases of plant-based Toona to the Food Bank of Contra Costa and Solano County as well as several other Bay Area food shelters.

Amidst the Covid-19 outbreak, the company's brand-new Lemon Grass Toona flavor has not yet arrived in grocery stores — but 100 percent of it is now being provided to people in need.…

People for the Ethical Treatment of Animals sent UC Berkeley chancellor Carol Christ a letter today requesting permission to place a banner on the university's famous clocktower that reads "It's High Time We Went Vegan. PETA."…

Now through May 5, healthcare workers and first responders can collect free "Thank You Meals" at any McDonald's location nationwide.

The promotion began on April 22.…

Celebrated chef-restaurateur Kyle Itani, who helms both Itani Ramen and Hopscotch Restaurant & Bar in Uptown Oakland, has just launched a brand-new project: a takeout sushi spot.

Operating out of Itani Ramen and serving its fare via pickup and delivery, Nikkei Sushi will be open Wednesday through Sunday, 2 p.m. - 8 p.m. during its soft opening with hours extending in the future.…

Celebrated chef-restaurateur Kyle Itani, who helms Itani Ramen and Hopscotch Restaurant & Bar in Uptown Oakland, has just launched a brand-new project: a takeout sushi spot.

California today announced its intent to declare bisphenol A a reproductive hazard. Under a state law known as Prop 65, warning signs would be required for consumer items that contain a certain high level of BPA.…

Stories you shouldn’t miss:

1. Alameda County Public Health Director Muntu Davis contends that gentrification should be examined in terms of health impacts because of the displacement and stress it causes for low-income residents, the Bay Area News Group$ reports.…

If you happen to run into any medical residents anytime soon, they may look a little fatigued and broke, especially if they happen to be residents or pediatricians of UCSF Benioff Children’s Hospital of Oakland. Today, the CIR/SEIU Healthcare union that represents resident physicians and pediatricians said it plans to rally in front of the hospital on Friday at 12:15 p.m. along with nurses and community leaders to demand better wagers and working conditions.…

An apparatus is disclosed which includes an electrolytic capacitive element with multiple capacitor sections.

A conductive composite is provided, which includes a conductive conjugated polymer and a mixture. The mixture includes (a) boron oxide, and (b) sulfur-containing compound, nitrogen-containing compound, or a combination thereof. A capacitor is also provided, which includes an anode electrode, a dielectric layer on the anode electrode, a cathode electrode, and an electrolyte between the dielectric layer and the cathode electrode, wherein the electrolyte includes the described conductive composite.

A capacitor structure is provided, which includes a positive electrode, a dielectric layer on the positive electrode, and an organic-inorganic composite layer on the dielectric layer. The capacitor structure also includes a negative electrode, and a conductive conjugated polymer electrolyte disposed between the organic-inorganic composite layer and the negative electrode.

A wiring device includes a housing that encloses a line voltage port and a low-voltage port for providing power to at least one removable load. The removable load can couple to a connector PCB. The connector PCB may include a tongue portion with retention surface features and a body portion with supporting circuitry. The tongue portion may be disposed within a low-voltage port of the wiring device. A plurality of conductive traces may extend from the body to the tongue of the connector PCB. The low voltage port may include sidewalls disposed around the tongue portion to guide the plug of a removable load into engagement with the conductive traces of the tongue portion so that one or more of the plurality of conductive traces electrically contact the removable load to deliver power to the removable load.

A switching regulator control circuit is used in a switching regulator that converts an input voltage into an output voltage by the switching of a switching device, and generates a switching signal for controlling the ON/OFF operation of the switching device. The switching regulator control circuit has a fault detector and a fault protector. The fault detector detects, based on the duty ratio of the switching signal or a variable correlated to it and included in a control signal used to generate the switching signal, a fault state where the duty ratio falls outside the normal modulation range. The fault protector stops the switching of the switching device when the fault detector detects a fault state.

A system for board-to-board interconnect is described herein. The system includes a first printed circuit board (PCB) having a first recess along a first edge of the first PCB that exposes a first solder pad on a layer of the first PCB. The system also includes a second PCB having a second recess along a second edge of the second PCB that exposes a second solder pad on a layer of the second PCB. The second recess is complementary to the first recess to allow the first PCB to mate with the second PCB. The first solder pad is aligned with the second solder pad when the first PCB is mated with the second PCB. The system additionally includes an assembly configured to electronically couple the first solder pad with the second solder pad.

An automation field device having a housing and a modular field device electronics unit located inside the housing. The electronics unit has a first circuit board having at least one first and one second plug-in connector element, wherein the first plug-in connector element is used to electrically connect a peripheral unit, wherein both the first and the second plug-in connector elements can be contacted essentially from the same preferred plug-in direction, and a second circuit board having at least one third plug-in connector element, wherein the circuit boards are arranged such that the second plug-in connector element is connected to the third plug-in connector element in a detachable manner to electrically connect the peripheral unit to the second circuit board, and the second circuit board has at least one opening, via which the first plug-in connector element of the first circuit board is accessible for connecting the peripheral unit.

According to one embodiment, a storage device includes an enclosure, and a circuit board assembly in the enclosure. The circuit board assembly includes a first circuit board, a second circuit board opposed to the first circuit board, a third circuit board opposed to the second circuit board, a first connector connecting the first and second circuit boards to each other, a second connector connecting the second and third circuit boards to each other, and is offset to the first connector in a plane direction, a first spacer between the first and second circuit boards, and a second spacer between the second and third circuit boards. The first spacer includes a support body at a position opposed to the second connector and in contact with the first and second circuit boards.

According to one embodiment, a storage device includes an enclosure, and a circuit board assembly in the enclosure. The circuit board assembly includes a first circuit board on which a heat-producing component is mounted, a second circuit board, a third circuit board, a first connector connecting the first and second circuit boards, a second connector connecting the second and third circuit boards, a first spacer sandwiched between the first and second circuit boards, and a second spacer sandwiched between the second and third circuit boards. The first spacer includes a spacer frame, a partition member opposed to the heat-producing component with a gap between, and a thermal transfer member attached to the partition member and in contact with the first circuit board.

The present invention is to provide a chassis switch, which comprises a chassis for accommodating a designated number of line cards therein; a backplane installed on the back side of the chassis and having a plurality of connectors disposed thereon; at least one line card plugged into one of the connectors corresponding thereto via a front side of the chassis and each having an access switch chip adapted to switch local network signals and an interconnect switch chip adapted to switch the signals between ports of the at least one line card; and a loop adapted to connect the corresponding ports of the access switch chip and the interconnect switch chip respectively through the connectors, so as to enable each line card plugged into the chassis switch to perform a local network switching function and a switching function between the at least one line card.

I was wondering why the iconic Civic Centre clock in Southampton is not lit up blue on Thursday at 8pm to clap for the NHS.

CHRISTINE Cassell (letters 28th April) asks a pertinent question when she enquires where the responsibility for the problem with PPEs for front line NHS workers lies.

I SHOULD like to pay tribute to Alan Wiltshire the Echo and Romsey Advertiser reporter whose death was sadly announced last week

ONLY a delusional Lib Dem like Martin Kyrle could come up with an excuse like this about his beloved party doing well in the last election when in fact they lost over half their seats, then blaming it on our undemocratic electoral system, it’s the system we have, and our MP’s are elected on that system.

HE MAY NOT be held in the highest regard by the public but there’s something to love about Piers Morgan on Good Morning Britain.

On Facebook, live streaming just got taken things a step further: with monetization. Many suspected monetizing virtual events was coming, and it seems to be rapidly arriving on the largest social network. Facebook has come forward with new updates to assert its dominance in this COVID-19 era of online entertainment and relationships. New Facebook Tools […]

The post Facebook Now Lets You Charge Entry To Livestream Events appeared first on DJ TechTools.

Right now there’s a lot of uncertainty in the world – with lots of people within our industry struggling to figure out what they’re going to do next. So when Bandcamp announced their fee-free Fridays were happening again, we decided to lean in and help our own community be supported in something great: making music. […]

The post 80+ DJTT Artists You Should Support Today On Bandcamp appeared first on DJ TechTools.

If you haven’t looked at Traktor DJ, Native Instruments’ iOS app (it runs on Mac and PC too) recently, a new update and the concurrent global stay-home happening seems like the perfect time to do it. The update to Traktor DJ 2.4 has a bunch of features that look like they’re straight out of a […]

The post Traktor DJ 2.4: Transport Control UI Improvements, Genre Sorting appeared first on DJ TechTools.

The provocative A Human Ounce at Central Works asks whether the creator can be separate from the creation. Central Works opens its 30th anniversary season with A Human Ounce, a new play by Nicole Parizeau that poses provocative questions. What is the value of great art, literature, music, commerce, scientific discovery — even Peet's coffee — when scandalous information about its creators or owners comes to light?…

Coming on the heels of the AB5 trauma, the coronavirus lockdown poses an extra economic threat. The COVID-19 pandemic has affected all facets of life in California and the world.…

A reading list specifically appropriate to these trying times. Okay, you're stuck in the house, but is it really that awful? OK, probably.…

Embodiments are directed to an electromagnetic memory device having a memory cell and an encapsulation layer formed over the memory cell. The memory cell may include a magnetic tunnel junction (MTJ), and the encapsulation layer may be formed from a layer of hydrogenated amorphous silicon. Amorphous silicon improves the coercivity of the MTJ but by itself is conductive. Adding hydrogen to amorphous silicon passivates dangling bonds of the amorphous silicon, thereby reducing the ability of the resulting hydrogenated amorphous silicon layer to provide a parasitic current path to the MTJ. The hydrogenated amorphous silicon layer may be formed using a plasma-enhanced chemical vapor deposition, which can be tuned to enable a hydrogen level of approximately 10 to approximately 20 percent. By keeping subsequent processing operations at or below about 400 Celsius, the resulting layer of hydrogenated amorphous silicon can maintain its hydrogen level of approximately 10 to 20 percent.

A method of making a MRAM device includes forming a magnetic tunnel junction on an electrode, the magnetic tunnel junction comprising a reference layer positioned in contact with the electrode, a tunnel barrier layer arranged on the reference layer, and a free layer arranged on the tunnel barrier layer; and depositing an encapsulating layer on and along sidewalls of the magnetic tunnel junction; wherein the exposing of the magnetic tunnel junction to hydrogen plasma is performed at a temperature from about 150 to about 250° C. An MRAM device including an encapsulating layer comprising either silicon nitride or aluminum oxide is also provided.

The semiconductor device according to the present invention has an upper electrode, a first lower layer wiring that also functions as a lower electrode, an electrical resistance-changing film interposed between the upper electrode and the first lower layer wiring, a second lower layer wiring, and a contact plug, the contact plug connecting to the upper electrode and to the second lower layer wiring. The present invention yields a semiconductor device with which it is possible to dispose elements in high density while maintaining the reliability and manufacturing yield of the electrical resistance-changing element.

A polymer compound comprising a structural unit represented by the formula (1): wherein R1, R2, R3 and R4 each independently represent an alkyl group, an aryl group or a monovalent heterocyclic group, and these groups optionally have a substituent, two rings A may be the same or different, and represent a thiophene ring, a benzothiophene ring or a thienothiophene ring, n represents 1 or 2, and X represents a halogen atom, an alkyl group, an alkoxy group, an alkylthio group, an amino group, an aryl group, a monovalent heterocyclic group, an alkenyl group or an alkynyl group, and these groups optionally have a substituent, and when n is 2, two groups X may be the same or different.