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Nanomedicine – a promising therapy for hematological malignancies

Biomater. Sci., 2020, 8,2376-2393
DOI: 10.1039/D0BM00129E, Review Article
Lifen Huang, Jun Huang, Junbin Huang, Hongman Xue, Zhiqing Liang, Jun Wu, Chun Chen
Nanoparticles (NPs) are used for the diagnosis and treatment of hematological tumors by loading various pharmacodynamic molecules.
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Topography induced stiffness alteration of stem cells influences osteogenic differentiation

Biomater. Sci., 2020, 8,2638-2652
DOI: 10.1039/D0BM00264J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Liangliang Yang, Qi Gao, Lu Ge, Qihui Zhou, Eliza M. Warszawik, Reinier Bron, King Wai Chiu Lai, Patrick van Rijn
Topography-driven alterations to single cell stiffness rather than alterations in cell morphology, is the underlying driver for influencing cell biological processes, particularly stem cell differentiation.
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Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis

Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper
Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
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Advances in living cell-based anticancer therapeutics

Biomater. Sci., 2020, 8,2344-2365
DOI: 10.1039/D0BM00036A, Review Article
He Dong, Xiao Xu, Leikun Wang, Ran Mo
This review summarizes recent advances in the applications of living cells as drug carriers or active drugs for anticancer drug delivery and cancer therapy.
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A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection

Biomater. Sci., 2020, 8,2682-2693
DOI: 10.1039/D0BM00162G, Paper
Yuanbiao Tu, Ji Tao, Fang Wang, Peifei Liu, Zhihao Han, Zhaolun Li, Yi Ma, Yueqing Gu
The designed novel peptide GB-6 with targeted GRPR-binding possesses more favorable pharmacokinetic properties and metabolic stability, as well as superior tumor-targeting ability in pancreatic cancer models, relative to BBN7–14.
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An intelligent vancomycin release system for preventing surgical site infections of bone tissues

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00255K, Paper
Yuan Li, Guang Li, Xiaoling Sha, Litao Li, Kuo Zhang, Daohong Liu, Yanfei Hao, Xu Cui, Lei Wang, Hao Wang
An intelligent anti-bacterial system can be constructed on implants during surgery.
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Outstanding Reviewers for Biomaterials Science in 2019

Biomater. Sci., 2020, 8,2343-2343
DOI: 10.1039/D0BM90031A, Editorial

We would like to take this opportunity to highlight the Outstanding Reviewers for Biomaterials Science in 2019, as selected by the editorial team for their significant contribution to the journal.
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A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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Functionalized Biomaterials to Combat Biofilm

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00526F, Minireview
Dan-ni Huang, Jing Wang, Kefeng Ren, Jian Ji
Pathogenic microbial biofilms readily form on implantable medical devices or human tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive strategies of biofilms, leaving a...
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Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting CD44v6 receptor in colon cancer cells

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper
Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
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Ex vivo toxicological evaluation of experimental anticancer gold(I) complexes with lansoprazole-type ligands

Toxicol. Res., 2019, 8,885-895
DOI: 10.1039/C9TX00149B, Paper
Natalia Estrada-Ortiz, Elena Lopez-Gonzales, Ben Woods, Stefan Stürup, Inge A. M. de Graaf, Geny M. M. Groothuis, Angela Casini
Novel experimental anticancer gold-based compounds were studied for their mechanisms of toxicity in healthy rat kidney and liver tissues, using the Precision Cut Tissue Slices (PCTS) technique.
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Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice

Toxicol. Res., 2019, 8,928-938
DOI: 10.1039/C9TX00191C, Paper
Xuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress

Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper
Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
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Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics

Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper
Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
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Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines

Toxicol. Res., 2019, 8,1016-1027
DOI: 10.1039/C9TX00179D, Paper
Open Access
Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux, Andreas Luch
To answer questions about nanoparticle toxicity, translocation and biokinetics following inhalation exposure, in vitro models should have functional barrier properties to mimic the in vivo situation as closely as possible.
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Central Board of Direct Taxes amends Rule 44G of Income-tax Rules 1962

It also states that if a resolution is arrived, the same shall be communicated to the assessee, who shall communicate his acceptance or non-acceptance within 30 days




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Lockdown period not to be counted for determining residency of NRIs: CBDT

There were apprehensions that this extended stay could lead to these individuals becoming Indian residents as per Section 6 of the Income Tax Act




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Sitharaman launches two exchanges to take on offshore currency market

The launch comes amid the world's most expansive coronavirus lockdown, which has crippled businesses and hurt trading volumes in the country's financial markets.




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Covid-19: Relief for NRIs, foreign visitors as tax residency rules eased

The government imposed a lockdown on March 24 and is yet to open up travel, including international flights.




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Ministry of Defence inks Rs 1,200 cr contract to boost electronics sector

The deal, Modernisation of Air Field Infrastructure Phase 2 (MAFI-2), follows from an earlier contract, called MAFI-1, which TPSED won in 2011 to upgrade 30 IAF airfields.




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Probing permanent dipoles in CdSe nanoplatelets with transient electric birefringence

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR00884B, Paper
Ivan Dozov, Claire Goldmann, Patrick Davidson, Benjamin Abécassis
Transient electric birefringence experiments with colloidal suspensions of zinc-blende CdSe semiconducting nanoplatelets prove that these particles bear a large ground-state electric dipole despite the cubic structure of bulk zinc-blende CdSe.
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RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10673A, Paper
Amit S. Yadav, N. Naga Venkata Radharani, Mahadeo Gorain, Anuradha Bulbule, Dattatrya Shetti, Gaurab Roy, Thejus Baby, Gopal C. Kundu
Peptide functionalized pH sensitive raloxifene-chitosan nanoparticles with high biocompatibility synergistically inhibit tumor growth and angiogenesis in breast cancer.
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Dual-sensitized Upconversion-assisted, Triple-band Absorbing Luminescent Solar Concentrators

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01008A, Paper
Sung Kyung Nam, Kiwon Kim, Ji-Hwan Kang, Jun Hyuk Moon
Luminescent solar concentrator-photovoltaic systems (LSC-PV) harvest solar light by using transparent photoluminescent plates, which is expected to be particularly useful for building-integrated PV applications. LSC panels that absorb multiple wavelength...
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Hybrid Phase 1T/2H-MoS2 with Controllable 1T Concentration and Its Promoted Hydrogen Evolution Reaction

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02525A, Paper
Yuxiao Zhang, Yasutaka Kuwahara, Kohsuke Mori, Catherine Louis, Hiromi Yamashita
MoS2 has been investigated as a low-cost alternative to Pt in electrochemical hydrogen evolution reaction. One of the promising method to further activate MoS2 is phase engineering. MoS2 generally exhibit...
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Proton exchange membrane with plasmon-active surface for enhancement of fuel cell effectivity

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00295J, Paper
Roman Elashnikov, Kristina Zahorjanova, Elena Miliutina, Zdenka Kolska, Miroslav Cieslar, Václav Švorčík, Oleksiy Lyutakov
The action of fuel cells with proton-exchanged membrane (PEM) requires the implementation of hydrogen oxidation reaction (HOR) and oxygen reduction reaction (ORR) on the opposite sides of PEM. Recently, based...
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Correction: Anomalous polarization dependence of Raman scattering and crystallographic orientation of black phosphorus

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR90098B, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jungcheol Kim, Jae-Ung Lee, Jinhwan Lee, Hyo Ju Park, Zonghoon Lee, Changgu Lee, Hyeonsik Cheong
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Functional nanoarrays for investigating stem cell fate and function

Nanoscale, 2020, 12,9306-9326
DOI: 10.1039/C9NR10963C, Review Article
Jin-Ho Lee, Jeffrey Luo, Hye Kyu Choi, Sy-Tsong Dean Chueng, Ki-Bum Lee, Jeong-Woo Choi
An overview of the recent progress of nanoarray synthesis and applications for controlling stem cell fate and monitoring live cell functions.
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Boosting the photocatalytic CO2 reduction of metal–organic frameworks by encapsulating carbon dots

Nanoscale, 2020, 12,9533-9540
DOI: 10.1039/D0NR01696A, Paper
Shumin Li, Kang Ji, Meng Zhang, Cangshuang He, Jin Wang, Zhengquan Li
Small carbon dots as cocatalysts were loaded in MOF particles for CO2 reduction and their location effect was explored.
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Ionic liquid assisted preparation and modulation of the photoluminescence kinetics for highly efficient CsPbX3 nanocrystals with improved stability

Nanoscale, 2020, 12,9569-9580
DOI: 10.1039/D0NR00579G, Paper
Ting Chen, Yanqiao Xu, Zhixiang Xie, Weihui Jiang, Lianjun Wang, Wan Jiang
A facile approach was performed to synthesize CsPbBr3 NCs with the assistance of ionic liquid [Bmim]Br, which could modulate the surface property and enhace the stability of NCs effectively.
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Analysis of sparse molecular distributions in fibrous arrangements based on the distance to the first neighbor in single molecule localization microscopy

Nanoscale, 2020, 12,9495-9506
DOI: 10.1039/C9NR10805J, Paper
Alan M. Szalai, Lucía F. Lopez, Miguel Ángel Morales-Vásquez, Fernando D. Stefani, Pedro F. Aramendía
We introduce a robust and sensitive metric to characterize the underlying structure responsible for the molecular distribution, even at a very low labeling density.
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Facile synthesis of core–shell structured Si@graphene balls as a high-performance anode for lithium-ion batteries

Nanoscale, 2020, 12,9616-9627
DOI: 10.1039/D0NR01346C, Paper
Anif Jamaluddin, Bharath Umesh, Fuming Chen, Jeng-Kuei Chang, Ching-Yuan Su
Encapsulating silicon (Si) nanoparticles with graphene nanosheets in a microspherical structure is proposed to increase electrical conductivity and solve stability issues when using Si as an anode material in lithium-ion batteries (LIBs).
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A high-efficiency ammonia-responsive solar evaporator

Nanoscale, 2020, 12,9680-9687
DOI: 10.1039/D0NR00791A, Paper
Jingjing Xing, Jintao Tong, Ye Liu, Yutong Guo, Lanjian Zhuge, Dafeng Zhang, Ruomeng Duan, Bo Song, Yu Zhao, Bin Dong
We report a highly efficient solar evaporator based on the TiO2NP and PPyNP composite with ammonia responsiveness.
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Oxygen vacancy-rich amorphous porous NiFe(OH)x derived from Ni(OH)x/Prussian blue as highly efficient oxygen evolution electrocatalysts

Nanoscale, 2020, 12,9557-9568
DOI: 10.1039/D0NR00607F, Paper
Shuang Wang, Xingbo Ge, Chao Lv, Cun Hu, Hongtai Guan, Jing Wu, Zhengnan Wang, Xianhui Yang, Yan Shi, Jiangfeng Song, Zhi Zhang, Akira Watanabe, Jinguang Cai
Oxygen vacancy-rich amorphous porous NiFe(OH)x on carbon paper is prepared through a two-step electrochemical depostion of Prussian blue nanocrystal layer and Ni(OH)x layer followed by an alkaline etching process for efficient OER catalysis.
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Enhanced motility in a binary mixture of active nano/microswimmers

Nanoscale, 2020, 12,9717-9726
DOI: 10.1039/D0NR01765E, Paper
Debajyoti Debnath, Pulak Kumar Ghosh, Vyacheslav R. Misko, Yunyun Li, Fabio Marchesoni, Franco Nori
The proposed mechanism of motility transfer from more active to less active species allows enhancing the motility of active nano-/microswimmers, e.g., Janus particles, as agents of chemical reactions, or weak sperm cells, for better fertilization.
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Enhanced type I photoreaction of indocyanine green via electrostatic-force-driven aggregation

Nanoscale, 2020, 12,9517-9523
DOI: 10.1039/D0NR01208D, Paper
Huizhen Fan, Yu Fan, Wenna Du, Rui Cai, Xinshuang Gao, Xinfeng Liu, Hao Wang, Lei Wang, Xiaochun Wu
ICG forms aggregates in positively charged mesoporous silica, which show an enhanced type I photoreaction pathway.
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Plasmonic nanopapers: flexible, stable and sensitive multiplex PUF tags for unclonable anti-counterfeiting applications

Nanoscale, 2020, 12,9471-9480
DOI: 10.1039/D0NR01223H, Paper
Hongrui Cheng, Yongfeng Lu, Dongyan Zhu, Lorenzo Rosa, Fei Han, Mingguo Ma, Wenyue Su, Paul S. Francis, Yuanhui Zheng
Highly flexible and stable plasmonic nanopaper comprised of silver nanocubes and cellulose nanofibres was fabricated through a self-assembly-assisted vacuum filtration method.
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NiSe2-anchored N, S-doped graphene/Ni foam as a free-standing bifunctional electrocatalyst for efficient water splitting

Nanoscale, 2020, 12,9866-9872
DOI: 10.1039/D0NR00879F, Paper
Jinhao Zhou, Zegao Wang, Dongxu Yang, Fei Qi, Xin Hao, Wanli Zhang, Yuanfu Chen
A strategy to synthesize free-standing electrocatalysts coupling active nanostructured NiSe2 with conductive S, N-doped 3D graphene foam (3DSNG) is presented and the hybrid delivers superior performances for the HER, OER and overall water splitting.
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In situ growth of well-aligned Ni-MOF nanosheets on nickel foam for enhanced photocatalytic degradation of typical volatile organic compounds

Nanoscale, 2020, 12,9462-9470
DOI: 10.1039/D0NR01027H, Paper
Xin Ding, Hongli Liu, Jiangyao Chen, Meicheng Wen, Guiying Li, Taicheng An, Huijun Zhao
Well-aligned Ni-MOF nanosheet arrays vertically grown on nickel foam were synthesized via a facile in situ solvothermal strategy, which exhibited remarkably improved photocatalytic activities to typical VOCs under visible light irradiation.
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Trace metals dramatically boost oxygen electrocatalysis of N-doped coal-derived carbon for zinc–air batteries

Nanoscale, 2020, 12,9628-9639
DOI: 10.1039/C9NR10800A, Paper
Huimin Liu, Xinning Huang, Zhenjie Lu, Tao Wang, Yaming Zhu, Junxia Cheng, Yue Wang, Dongling Wu, Zhenyu Sun, Alex W. Robertson, Xingxing Chen
The commercialization of metal–air batteries requires efficient, low-cost, and stable bifunctional electrocatalysts for reversible electrocatalysis of the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER).
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Point defect induced intervalley scattering for the enhancement of interlayer electron transport in bilayer MoS2 homojunctions

Nanoscale, 2020, 12,9859-9865
DOI: 10.1039/D0NR01339K, Paper
Yang Ou, Zhuo Kang, Qingliang Liao, Shihan Gao, Zheng Zhang, Yue Zhang
The interlayer transport of MoS2 homojunctions can be enhanced by point defect induced K–Q intervalley scattering.
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2D molybdenum disulphide nanosheets incorporated with single heteroatoms for the electrochemical hydrogen evolution reaction

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01295E, Minireview
Thomas H. M. Lau, John S. Foord, S. C. Edman Tsang
2D nanosheets give enhanced surface area to volume ratios in particle morphology and they can also provide defined surface sites to disperse foreign atoms.
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Quantitative encapsulation and retention of 227Th and decay daughters in core–shell lanthanum phosphate nanoparticles

Nanoscale, 2020, 12,9744-9755
DOI: 10.1039/D0NR01172J, Paper
M. Toro-González, A. N. Dame, C. M. Foster, L. J. Millet, J. D. Woodward, J. V. Rojas, S. Mirzadeh, S. M. Davern
La(227Th)PO4 core +2 shells nanoparticles retained >99.75% of activity from 227Th and decay daughters (223Ra, 211Pb) for targeted alpha therapy.
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Tuning the electronic structure of transition metals embedded in nitrogen-doped graphene for electrocatalytic nitrogen reduction: a first-principles study

Nanoscale, 2020, 12,9696-9707
DOI: 10.1039/D0NR00072H, Paper
Xiaonan Zheng, Yuan Yao, Ya Wang, Yang Liu
The Fe/Mn–N–C catalyst is a promising candidate for the NRR as it shows significantly improved NRR catalytic activity and strong selectivity against the HER.
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Elucidating the relationship between nanoparticle morphology, nuclear/magnetic texture and magnetic performance of sintered SrFe12O19 magnets

Nanoscale, 2020, 12,9481-9494
DOI: 10.1039/D0NR01728K, Paper
Matilde Saura-Múzquiz, Anna Zink Eikeland, Marian Stingaciu, Henrik Lyder Andersen, Cecilia Granados-Miralles, Maxim Avdeev, Vladimir Luzin, Mogens Christensen
The relationship between nanoparticle morphology, self-induced atomic/magnetic texture and magnetic properties of high-performance hexaferrite magnets is elucidated using neutron/X-ray pole figure analysis and neutron/synchrotron powder diffraction.
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Double Fano resonances in hybrid disk/rod artificial plasmonic molecules based on dipole-quadrupole coupling

Nanoscale, 2020, 12,9776-9785
DOI: 10.1039/D0NR00461H, Paper
Zhiquan Chen, Shi Zhang, Yiqin Chen, Yanjun Liu, Ping Li, Zhaolong Wang, Xupeng Zhu, Kaixi Bi, Huigao Duan
Double Fano resonances can be aroused in a simple disk and rods coupled artificial plasmonic molecule. Two Fano peaks can be independently tuned by changing one rod length or the gap distances between rods and disk.
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Theoretical Anchoring Effect of New Phosphorus Allotropes for Lithium-sulfur Batteries

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02359K, Paper
Chunmei Li, Linxin He, Jianglei Luo, Jianfeng Tang, Nanpu Cheng, Zhiqian Chen
Lithium-sulfur battery system has appeared as a new-generation alternative to lithium-ion batteries with 5-7 times higher specific energy density than conventional lithium-ion batteries. But its commercial implementation is still impeded...
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Mild generation of surface oxygen vacancy on CeO2 for improved CO2 photoreduction activity.

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00717J, Paper
Min Wang, Meng Shen, Xixiong Jin, Jianjian Tian, Yajun Zhou, Yiran Shao, Lingxia Zhang, Yongsheng Li, Jianlin Shi
The vacancy defects of semiconductor photocatalysts play a key role in enhancing their photocatalytic CO2 reduction activity. In this work, CeO2 was chosen as a model catalyst and oxygen vacancy...
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Single-wavelength phototheranostics for colon cancer via thiolytic reaction

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02393K, Paper
Yucheng Zhu, Chao Chen, Qinghua Wu, Guoliang Yang, Zhiyong Liu, Erhong Hao, Hongliang Cao, Yun Gao, Weian Zhang
It’s a huge challenge to develop effective nanosystems combined the capabilities of diagnoses and therapies together for colon cancer in clinic. Herein, we constructed a far-red absorbing phototheranostic nanosystem (FR-H2S)...
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The influence of surface roughness on the adhesive interactions and phase behavior of suspensions of calcite nanoparticles

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00834F, Paper
Open Access
Juan D. Olarte-Plata, Goran Svaland, Fernando Bresme
We investigate the impact of nanoparticle roughness on the phase behaviour of suspensions lue{in models} of calcium carbonate nanoparticles. We use a Derjaguin approach that incorporates roughness effects and interactions...
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Ultrathin Two-Dimensional Vertical Ferroelectric Tunneling Junction based on CuInP2S6 Monolayer

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01475C, Paper
Min Zhao, Gaoyang Gou, Xiangdong Ding, Jun Sun
Ferroelectric (FE) materials, especially ABO3 FE perovskite oxides have been extensively studied for their important applications in memories, electronics and sensors. However, the integration of FE perovskite oxides into minimized...
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