Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00688G, Paper

Larissa G. Velasco, Danielly S. Rocha, Richard P. S. de Campos, Wendell K. T. Coltro
Digital microfluidics (DMF) is a platform that allows the automated manipulation of individual droplets, ranging from nanoliters to microliters, and coupling sensing techniques can be facilitated by paper-based devices (PAD).
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01227E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Amanda D. French, Kirby P. Hobbs, Richard M Cox, Isaac J. Arnquist
Interference removal in inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) is strongly dependent on the gas selected for use within the collision/reaction cell.
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Analyst, 2024, 149,5255-5264
DOI: 10.1039/D4AN00780H, Paper

Lucille Kuster, Priscilia Diane Mamboundou, Asma Boushih, Yasmine Rassi, Alexandre Benoît, Samuel Parent-Vézina, Michel Lord-St-Vincent, Jean-Philippe Guillemette, Mathieu Frenette
Edible oils oxidize in air to form a variety of α,β-unsaturated carbonyl containing products collectively called ‘lipid-derived electrophiles’. A commercially available “turn-on” fluorescent probe 7-mercapto-4-methylcoumarin is used to quantify ‘electrophilic content’ in oil-containing foods.
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Analyst, 2024, 149,5243-5254
DOI: 10.1039/D4AN00813H, Paper

Chunhao Wei, Xinxin Xu, Lingling Guo, Aihua Qu, Aihong Wu, Chuanlai Xu, Hua Kuang
LFIA has been successfully applied to actual sample detection for Hbl B and L2, with an LOD of 1 ng mL⁻¹.
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Analyst, 2024, 149,5165-5173
DOI: 10.1039/D4AN00973H, Paper

Emily Dominique, Christophe Renault
The strong adsorption of 6PPD onto glassy carbon and its reversible two electron oxidation enables simple and sensitive electrochemical detection with an LOD of 10 nM.
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Analyst, 2024, 149,5287-5297
DOI: 10.1039/D4AN00916A, Paper

Jian Song, Wenlong Liang, Hongtao Huang, Hongyan Jia, Shouning Yang, Chunlei Wang, Huayan Yang
A novel feature-extractor-based fusion-assisted machine learning strategy was developed for high accuracy and rapid strain differentiation using MALDI-TOF MS and Raman spectra.
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Analyst, 2024, 149,5232-5242
DOI: 10.1039/D4AN00958D, Paper

Xuyang Ma, Liqiang Liu, Shanshan Song, Hua Kuang, Chuanlai Xu, Xinxin Xu
The determination of glyphosate in soybean (a) and corn (b) samples using a lateral strip assay.
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Analyst, 2024, 149,5277-5286
DOI: 10.1039/D4AN00649F, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Naghmeh Aboualigaledari, Anitha Jayapalan, Panesun Tukur, Mengxin Liu, Frank Tukur, Yanling Zhang, Gerald Ducatte, Madan Verma, Janet Tarus, Simona E. Hunyadi Murph, Jianjun Wei
Hybrid nanoparticles composed of gold nanoparticles and carbon nanodots provide great signal amplification in SERS detection of herbicide molecules.
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Analyst, 2024, 149,5298-5305
DOI: 10.1039/D4AN00995A, Paper

Keqi Ye, Jiacheng Ye, Yinghua Yan, Chuan-Fan Ding
This work introduces rapid quantification of disaccharide isomers by derivatization in combination with ion mobility spectrometry in beer and milk.
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Analyst, 2024, 149,5265-5276
DOI: 10.1039/D4AN01102C, Paper

Longmei Yao, Xue Mei, Jiajia Zhi, Wenchang Wang, Qingyi Li, Ding Jiang, Xiaohui Chen, Zhidong Chen
In this study, a novel electrochemiluminescent (ECL) sensor for highly sensitive detection of trilobatin (Tri) was developed based on silver metal–organic frameworks (AgMOFs) and nitrogen-doped carbon quantum dots (N-CDs).
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Analyst, 2024, 149,5306-5312
DOI: 10.1039/D4AN00747F, Paper

Qun Wu, Chengbin Liu, Yifan Liu, Tao Li
A fluorescent probe for live-cell imaging of nitric oxide (NO) allows for sensitive detection of NO in cancer cells, thereby enabling real-time monitoring of doxorubicin-induced apoptosis and lipopolysaccharide-triggered inflammatory responses.
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Analyst, 2024, 149,5206-5212
DOI: 10.1039/D4AN01165A, Paper

Xueying Zhu, Tikai Liang, Dianping Tang
A highly efficient photoelectrochemical (PEC) strategy was proposed for the determination of ascorbic acid (AA).
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Analyst, 2024, 149,5191-5205
DOI: 10.1039/D4AN01061B, Paper

Ahmad Hasan As'ari, Rizky Aflaha, Laila Katriani, Ahmad Kusumaatmaja, Iman Santoso, Rike Yudianti, Kuwat Triyana
Utilizing the specific interaction between carboxylic groups and ammonia gas has led to the development of an ultra-sensitive ammonia sensor based on a quartz crystal microbalance using nanofibers overlaid with carboxylic group-functionalized MWCNTs.
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Analyst, 2024, 149,5320-5328
DOI: 10.1039/D4AN00961D, Paper

Yusuke Hibi
Nonlinear reference-free analysis in pyrolysis-MS enables accurate compositional analysis even in reactive and interactive systems.
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Analyst, 2024, 149,5329-5335
DOI: 10.1039/D4AN00793J, Paper

Kelli Moseman, Sasha Noble, Sage Sanders, Huiyuan Guo, John R. Swierk
REACH legislation in Europe has banned the use of Pigment Blue 15:3 and Pigment Green 7 in tattoo inks and permanent makeups and requires all labels include an accurate list of ingredients.
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Analyst, 2024, 149,5156-5164
DOI: 10.1039/D4AN01109K, Minireview

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Derya Yaman, Melanie Jimenez, Sofia Ferreira Gonzalez, Damion Corrigan
Electrochemical detection of liver biomarkers, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), bilirubin, gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), and albumin, all with vital physiological functions.
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Analyst, 2024, 149,5213-5224
DOI: 10.1039/D4AN01028K, Paper

Kaihao Mao, Ye Tao, Wenshang Guo, Qisheng Yang, Meiying Zhao, Xiangyu Meng, Yinghao Zhang, Yukun Ren
An automated microscope image detection device (A-MMD) is designed to detect fluorescent droplets in droplet digital PCR images captured by multiple microscopes.
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Analyst, 2024, 149,5353-5359
DOI: 10.1039/D4AN00975D, Paper

Yang Yang, Rui Jiang, En-lai Yang, Jiahao Liang, Ying Xu, Xu-dong Wang
Highly sensitive and reversible fluorescence H₂O₂ sensor with a limit of detection of 0.02 ppm had been developed. The sensor responded rather fast, had high stability, and can be massively produced with good batch-to-batch consistency.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00983E, Paper

Kwanhwi Ko, Hajun Yoo, Sangheon Han, Won Seok Chang, Donghyun Kim
The combination of dielectrophoresis and surface-enhanced Raman spectroscopy provides an effective method for analyzing the Raman characteristics and the dielectrophoretic behavior of polystyrene beads and U-87MG cells in a microfluidic environment.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01160K, Paper

Maria Nikitina, Pavel Khramtsov, Stepan Devyatov, Rishat Valeev, Marina Eryomina, Andrey Chukavin, Mikhail Rayev
LaNiO₃ nanosphere-based NLISA has been demonstrated for the first time. The assay enables the CRP effective detection with high sensitivity.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00964A, Paper

Feng-yan Kuang, De-jun Hu, Lu Wang, Fei Chen, Guang-ping Lv
The selection of the matrix is crucial for matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI).
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01005A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Oksana A. Bondar, Gamal A. I. Moustafa, Thomas B. R. Robertson
The NMR hyperpolarisation technique SABRE has been used to hyperpolarise ¹³C labelled pyruvate in a predominantly aqueous solution which has then been measured by benchtop NMR.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01082E, Critical Review

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Jagpreet Singh Sidhu, Gurjot Kaur, Atharva Rajesh Chavan, Mandeep Chahal, Rajeev Taliyan
The use of chemiluminophores for tracing enzymatic activities in live-cell imaging has gained significant attention, making them valuable tools for diagnostic applications. Among various chemiluminophores, the phenoxy-1,2-dioxetane scaffold exhibits significant...
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Analyst, 2024, 149,5372-5380
DOI: 10.1039/D4AN00861H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Felix Frank, Daniela Tomasetig, Peter Nahringbauer, Wolfgang Ipsmiller, Gerd Mauschitz, Karin Wieland, Bernhard Lendl
Coupling Raman and VIS spectroscopy enables the study of AgNP aggregations induced by surfactants.
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Analyst, 2024, 149,5455-5462
DOI: 10.1039/D4AN00965G, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Hao Zhou, Weixiong Zhao, Weihua Cui, Bingxuan Lv, Bo Fang, Nana Yang, Guangfeng Xiang, Weijun Zhang, Lunhua Deng, Weidong Chen
A simple five-parameters spectrogram model for the VIPA spectrometer frequency calibration is developed, which has the advantages of high accuracy, simple setup and easy-to-solve.
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Analyst, 2024, 149,5443-5454
DOI: 10.1039/D4AN00956H, Paper

Patrycja Leszczenko, Anna M. Nowakowska, Patrycja Dawiec, Karolina Czuja, Justyna Jakubowska, Marta Zabczynska, Agata Pastorczak, Kinga Ostrowska, Szymon Tott, Wojciech Mlynarski, Malgorzata Baranska, Katarzyna Majzner
Acute lymphoblastic leukaemia (ALL) is a complex disease in pediatric oncology, necessitating accurate diagnostic strategies for effective treatment planning.
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Analyst, 2024, 149,5381-5393
DOI: 10.1039/D4AN00868E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Edoardo Farnesi, Matteo Calvarese, Chen Liu, Carl Messerschmidt, MohammadSadegh Vafaeinezhad, Tobias Meyer-Zedler, Dana Cialla-May, Christoph Krafft, Jonas Ballmaier, Orlando Guntinas-Lichius, Michael Schmitt, Jürgen Popp
The study demonstrates the potential of advanced vibrational spectroscopy to reveal the complex molecular composition of cerumen, suggesting its promising application as a non-invasive diagnostic tool for identifying disease-related biomarkers.
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Analyst, 2024, 149,5504-5517
DOI: 10.1039/D4AN01142B, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Enoch Amoah, Taghi Sahraeian, Ayesha Seth, Abraham K. Badu-Tawiah
Halide adduction enables the generation of diagnostic fragments ions for oligosaccharide isomers enabling multi-dimensional mass spectrometry analysis without prior separation.
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Analyst, 2024, 149,5482-5490
DOI: 10.1039/D4AN01186D, Paper

Jin Wang, Xiangmei Li, Hongtao Lei, Juewen Liu
Using capture-SELEX, short aptamers for metronidazole and ibuprofen were isolated and they can be used for the detection of these drugs illicitly added to soft drinks.
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Analyst, 2024, 149,5423-5432
DOI: 10.1039/D4AN01015A, Paper

Darcy Cochran, Panteleimon G. Takis, James L. Alexander, Benjamin H. Mullish, Nick Powell, Julian R. Marchesi, Robert Powers
Evaluating how sample preparation methods and data analysis platforms impact measured metabolite concentrations underscores the need for a universal consensus in the followed approaches for metabolomics data analysis.
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Analyst, 2024, 149,5411-5422
DOI: 10.1039/D4AN01136H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Mohammad Hossein Ghanbari, Markus Biesalski, Oliver Friedrich, Bastian J. M. Etzold
Screen printing was employed for the first time to examine the effect of electrode size and arrangement on the performance of a microfluidic paper-based electroanalytical device for clozapine sensing.
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Analyst, 2024, 149,5394-5400
DOI: 10.1039/D4AN01060D, Paper

Xiaoqing Zhang, Shanglin Li, Mei Liu
A fluorescence biosensing strategy was developed based on CuS-BSA for sensitive and rapid detection of Escherichia coli.
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Analyst, 2024, 149,5527-5534
DOI: 10.1039/D4AN01107D, Paper

Hongliang Ma, Shiqi Wang, Gaoxuan Wang, Qilei Zhang, Shenlong Zha, Xueyuan Cai, Lingli Li, Pan Pan, Qiang Liu, Shengbao Zhan
A novel method combining dual-channel concentration signal averaging with detector gain optimization is proposed to improve the measurement precision and response speed of the sensor within the 1–10 second integration time.
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Analyst, 2024, 149,5463-5475
DOI: 10.1039/D4AN01044B, Paper

Zuriel Erikson Joven, Piyush Raj, Ishan Barman
Monte Carlo simulations of spatially offset Raman spectroscopy (SORS) produce widely-applicable, quantitative frameworks for optimizing and interpreting SORS experiments.
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Analyst, 2024, 149,5491-5503
DOI: 10.1039/D4AN00866A, Paper

Vandana Kuttappan Nair, Chandrika Sharma, Shrawan Kumar, Mrittika Sengupta, Souradyuti Ghosh
Comprehensive quantitative analysis of various ligation and digestion conditions to identify and minimize non-specific amplification in RCA bioanalytical methods.
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Analyst, 2024, 149,5563-5571
DOI: 10.1039/D4AN01127A, Paper

Zhentao Sun, Youquan Zhao, Yameng Liu, Chen Chen, Hao Chen
A paper-based microfluidic disc is used for the rapid determination of various nutrients in water.
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Analyst, 2024, 149,5518-5526
DOI: 10.1039/D4AN01139B, Paper

Tapparath Leelasattarathkul, Thithawat Trakoolwilaiwan, Kawin Khachornsakkul
A simple and low-cost distance-based paper analytical device (dPAD) was combined with gold nanomaterials for uric acid quantification.
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Analyst, 2024, 149,5535-5545
DOI: 10.1039/D4AN00729H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Katherine J. I. Ember, Nassim Ksantini, Frédérick Dallaire, Guillaume Sheehy, Trang Tran, Mathieu Dehaes, Madeleine Durand, Dominique Trudel, Frédéric Leblond
Raman spectroscopy and machine learning is used in combination to detect COVID-19 positive saliva in liquid form.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01297F, Paper

Adrian Ebenazer Paul, Gaurav Gaur, Abdullah Alswieleh, Jerry J. Wu, Sambandam Anandan
The concentration of sodium ions can cause severe imbalances (high pressure on blood vessels, swelling of the muscular tissues, and misfunctioning of the whole nervous system) to the system in...
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00784K, Paper

Liang Ma, Wenqing Gao, Xiangyang Hu, Dongdong Zhou, Chenlu Wang, Jiancheng Yu, Keqi Tang
An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and 1D neural network combining ResNet and SENet is proposed and successfully applied to the diagnosis of ovarian cancer with high accuracy and strong fitting ability.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01203H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Claire E. Hefner, Prakash Aryal, Eric Brack, Todd Alexander, Charles S. Henry
Assessment of pesticide exposure using a fast-flow capillary device (created with Bio.Render.com).
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01244E, Paper

Léa Habib, Rime Michael-Jubeli, Marie Abboud, Roger Lteif, Ali Tfayli
Blue light alters lipids and proteins in the reconstructed human epidermis.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01112K, Paper

Johan Yi, Suyeon Kim, Chungmin Han, Jaesung Park
A TIRF microscopy-based method for single vesicle aggregation analysis enables precise assessment of EV aggregation under various conditions, enhancing EV characterization and functional analysis.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01103A, Critical Review

Wenteng Tang, Junlei Han, Wenhong Zhang, Huimin Li, Jun Chen, Wei Song, Li Wang
Molecularly imprinted polymer sensors, combined with electrochemical, optical, thermal, and acoustic detection technologies, detect biomarkers for key cardiovascular diseases: coronary artery disease, acute myocardial infarction, and heart failure.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01260G, Paper

Sunil S. Adav, Yan Wen Crystal Tan, Choon Teck Low, Song Wei Loo, Ridhwan Yusoff, Archana Gautam, Yuk Lin Yong, Chiew Yung Yang, Chin Chin Lim, Kee Woei Ng
In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01175A, Minireview

Chenyang Xu, Huanhuan Shi, Zhongjian Tan, Yun Zheng, Weizheng Xu, Zhengxian Dan, Jiacong Liao, Zhiying Dai, Yali Zhao
This review discusses the formation and manipulation of magnetic droplets on microfluidic chips and classifies related detection techniques. Applications in biomedicine were reviewed. Future development of this emerging field is provided.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01305K, Paper

Yi-Xuan Li, Yu-Xuan Dai, Ju-Zheng Wang, Jérôme Chauvin, Xueji Zhang, Serge Cosnier, Robert Marks, Dan Shan
The concentration of zinc ions in semen is significantly correlated to the sperm viability and male fertility. In this work, a reliable ratiometric fluorescence probe (ZIF-9-TCPP) based on the efficient...
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01269K, Paper

Hong Zeng, Xiao Ma, Shufen Pan, Yuting Han, Yanyan Tang, Yulan Fan, Yongquan Wu
Inflammation is a complex physiological response involving various cellular and molecular events. Sulfur dioxide (SO2), which is usually in the form of HSO3- and SO32- under physiological conditions, plays a...
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01164C, Paper

Anil Sharma, Thomas Hulse, Aymen H. Qatamin, Monica Moreno, Klester S. Souza, Marcelo B. Pereira, Fabricio S. Campos, Leandro B. Carneiro, Antonio M. H. de Andrade, Paulo M. Roehe, Flavio Horowitz, Sergio B. Mendes
This article focuses on the application of electrochemically modulated surface plasmon waves for structural characterization and for assessing signal transduction performance of redox-labeled DNA-based sensing platforms.
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