the Pediatric injectable drugs : the teddy bear book By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9781585285402 (electronic bk.) Full Article
the Ocular therapeutics handbook : a clinical manual By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Onofrey, Bruce E., author.Callnumber: OnlineISBN: 197510904X Full Article
the Nanobiomaterial engineering : concepts and their applications in biomedicine and diagnostics By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9789813298408 (electronic bk.) Full Article
the Models of tree and stand dynamics : theory, formulation and application By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Mäkelä, Annikki, authorCallnumber: OnlineISBN: 9783030357610 Full Article
the Milk and dairy foods : their functionality in human health and disease By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9780128156049 (electronic bk.) Full Article
the Mayo Clinic strategies to reduce burnout : 12 actions to create the ideal workplace By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Swensen, Stephen J., author.Callnumber: OnlineISBN: 9780190848996 electronic book Full Article
the Low-dose radiation effects on animals and ecosystems : long-term study on the Fukushima Nuclear Accident By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9789811382185 (electronic bk.) Full Article
the Introduction to the chemistry of food By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Zeece, Michael, author.Callnumber: OnlineISBN: 9780128117262 (electronic bk.) Full Article
the Interaction of nanomaterials with the immune system By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783030339623 (electronic bk.) Full Article
the Insect collection and identification : techniques for the field and laboratory By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Gibb, Timothy J., author.Callnumber: OnlineISBN: 9780128165713 (ePub ebook) Full Article
the In china's wake : how the commodity boom transformed development strategies in the global south By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Jepson, Nicholas, author.Callnumber: OnlineISBN: 9780231547598 electronic book Full Article
the Implants in the aesthetic zone : a guide for treatment of the partially edentulous patient By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319726014 (electronic bk.) Full Article
the Imaging of the temporomandibular joint By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319994680 (electronic book) Full Article
the Hypertension in the dog and cat By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783030330200 (electronic bk.) Full Article
the Health issues and care system for the elderly By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9789811317620 (electronic bk.) Full Article
the Handbook of the mammals of Europe By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319650388 electronic book Full Article
the Handbook of the cerebellum and cerebellar disorders By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319979113 (electronic bk.) Full Article
the Handbook of geotechnical testing : basic theory, procedures and comparison of standards By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Li, Yanrong (Writer on geology), author.Callnumber: OnlineISBN: 0429323743 electronic book Full Article
the Green criminology and green theories of justice : an introduction to a political economic view of eco-justice By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Lynch, Michael J., authorCallnumber: OnlineISBN: 9783030285739 (electronic bk.) Full Article
the Functional foods in cancer prevention and therapy By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9780128165386 (electronic bk.) Full Article
the Fractures in the elderly : a guide to practical management By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319722283 (electronic bk.) Full Article
the Epidemics and society : from the Black Death to the present By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Snowden, Frank M. (Frank Martin), 1946- author.Callnumber: OnlineISBN: 9780300249149 (electronic book) Full Article
the Effective treatments for pain in the older patient By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9781493988273 (electronic bk.) Full Article
the DeJong's the neurologic examination By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Campbell, William W., Jr. (William Wesley), author.Callnumber: OnlineISBN: 9781496386168 (hardcover) Full Article
the Cullin-RING ligases and protein neddylation : biology and therapeutics By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9789811510250 (electronic bk.) Full Article
the Computational processing of the Portuguese language : 14th International Conference, PROPOR 2020, Evora, Portugal, March 2-4, 2020, Proceedings By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: PROPOR (Conference) (14th : 2020 : Evora, Portugal)Callnumber: OnlineISBN: 9783030415051 (electronic bk.) Full Article
the Common problems in the newborn nursery : an evidence and case-based guide By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319956725 (electronic bk.) Full Article
the Clinical approaches in endodontic regeneration : current and emerging therapeutic perspectives By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319968483 (electronic bk.) Full Article
the Breakfast cereals and how they are made : raw materials, processing, and production By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9780128120446 (electronic bk.) Full Article
the Biodiversity of the Himalaya : Jammu and Kashmir State By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9789813291744 (electronic bk.) Full Article
the Bacteriophages : biology, technology, therapy By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Callnumber: OnlineISBN: 9783319405988 electronic book Full Article
the Arctic plants of Svalbard : what we learn from the green in the treeless white world By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Lee, Yoo Kyung, authorCallnumber: OnlineISBN: 9783030345600 (electronic bk.) Full Article
the Aquatic biopolymers : understanding their industrial significance and environmental implications By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Olatunji, Ololade.Callnumber: OnlineISBN: 9783030347093 (electronic bk.) Full Article
the Anomalies of the Developing Dentition : a Clinical Guide to Diagnosis and Management By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Soxman, Jane A., author.Callnumber: OnlineISBN: 9783030031640 (electronic bk.) Full Article
the 100 cases in clinical pharmacology, therapeutics and prescribing By dal.novanet.ca Published On :: Fri, 1 May 2020 19:44:43 -0300 Author: Layne, Kerry, author.Callnumber: OnlineISBN: 9780429624537 electronic book Full Article
the Hays County Joins the Texas Purchasing Group by BidNet Direct By www.prweb.com Published On :: Hays County announced it has joined the Texas Purchasing Group and will be publishing and distributing upcoming bid opportunities on the system along with their current platform in these unprecedented...(PRWeb April 09, 2020)Read the full story at https://www.prweb.com/releases/hays_county_joins_the_texas_purchasing_group_by_bidnet_direct/prweb17021429.htm Full Article
the Optimal prediction in the linearly transformed spiked model By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Edgar Dobriban, William Leeb, Amit Singer. Source: The Annals of Statistics, Volume 48, Number 1, 491--513.Abstract: We consider the linearly transformed spiked model , where the observations $Y_{i}$ are noisy linear transforms of unobserved signals of interest $X_{i}$: egin{equation*}Y_{i}=A_{i}X_{i}+varepsilon_{i},end{equation*} for $i=1,ldots ,n$. The transform matrices $A_{i}$ are also observed. We model the unobserved signals (or regression coefficients) $X_{i}$ as vectors lying on an unknown low-dimensional space. Given only $Y_{i}$ and $A_{i}$ how should we predict or recover their values? The naive approach of performing regression for each observation separately is inaccurate due to the large noise level. Instead, we develop optimal methods for predicting $X_{i}$ by “borrowing strength” across the different samples. Our linear empirical Bayes methods scale to large datasets and rely on weak moment assumptions. We show that this model has wide-ranging applications in signal processing, deconvolution, cryo-electron microscopy, and missing data with noise. For missing data, we show in simulations that our methods are more robust to noise and to unequal sampling than well-known matrix completion methods. Full Article
the Consistent selection of the number of change-points via sample-splitting By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Changliang Zou, Guanghui Wang, Runze Li. Source: The Annals of Statistics, Volume 48, Number 1, 413--439.Abstract: In multiple change-point analysis, one of the major challenges is to estimate the number of change-points. Most existing approaches attempt to minimize a Schwarz information criterion which balances a term quantifying model fit with a penalization term accounting for model complexity that increases with the number of change-points and limits overfitting. However, different penalization terms are required to adapt to different contexts of multiple change-point problems and the optimal penalization magnitude usually varies from the model and error distribution. We propose a data-driven selection criterion that is applicable to most kinds of popular change-point detection methods, including binary segmentation and optimal partitioning algorithms. The key idea is to select the number of change-points that minimizes the squared prediction error, which measures the fit of a specified model for a new sample. We develop a cross-validation estimation scheme based on an order-preserved sample-splitting strategy, and establish its asymptotic selection consistency under some mild conditions. Effectiveness of the proposed selection criterion is demonstrated on a variety of numerical experiments and real-data examples. Full Article
the The numerical bootstrap By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Han Hong, Jessie Li. Source: The Annals of Statistics, Volume 48, Number 1, 397--412.Abstract: This paper proposes a numerical bootstrap method that is consistent in many cases where the standard bootstrap is known to fail and where the $m$-out-of-$n$ bootstrap and subsampling have been the most commonly used inference approaches. We provide asymptotic analysis under both fixed and drifting parameter sequences, and we compare the approximation error of the numerical bootstrap with that of the $m$-out-of-$n$ bootstrap and subsampling. Finally, we discuss applications of the numerical bootstrap, such as constrained and unconstrained M-estimators converging at both regular and nonstandard rates, Laplace-type estimators, and test statistics for partially identified models. Full Article
the The multi-armed bandit problem: An efficient nonparametric solution By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Hock Peng Chan. Source: The Annals of Statistics, Volume 48, Number 1, 346--373.Abstract: Lai and Robbins ( Adv. in Appl. Math. 6 (1985) 4–22) and Lai ( Ann. Statist. 15 (1987) 1091–1114) provided efficient parametric solutions to the multi-armed bandit problem, showing that arm allocation via upper confidence bounds (UCB) achieves minimum regret. These bounds are constructed from the Kullback–Leibler information of the reward distributions, estimated from specified parametric families. In recent years, there has been renewed interest in the multi-armed bandit problem due to new applications in machine learning algorithms and data analytics. Nonparametric arm allocation procedures like $epsilon $-greedy, Boltzmann exploration and BESA were studied, and modified versions of the UCB procedure were also analyzed under nonparametric settings. However, unlike UCB these nonparametric procedures are not efficient under general parametric settings. In this paper, we propose efficient nonparametric procedures. Full Article
the Optimal rates for community estimation in the weighted stochastic block model By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Min Xu, Varun Jog, Po-Ling Loh. Source: The Annals of Statistics, Volume 48, Number 1, 183--204.Abstract: Community identification in a network is an important problem in fields such as social science, neuroscience and genetics. Over the past decade, stochastic block models (SBMs) have emerged as a popular statistical framework for this problem. However, SBMs have an important limitation in that they are suited only for networks with unweighted edges; in various scientific applications, disregarding the edge weights may result in a loss of valuable information. We study a weighted generalization of the SBM, in which observations are collected in the form of a weighted adjacency matrix and the weight of each edge is generated independently from an unknown probability density determined by the community membership of its endpoints. We characterize the optimal rate of misclustering error of the weighted SBM in terms of the Renyi divergence of order 1/2 between the weight distributions of within-community and between-community edges, substantially generalizing existing results for unweighted SBMs. Furthermore, we present a computationally tractable algorithm based on discretization that achieves the optimal error rate. Our method is adaptive in the sense that the algorithm, without assuming knowledge of the weight densities, performs as well as the best algorithm that knows the weight densities. Full Article
the New $G$-formula for the sequential causal effect and blip effect of treatment in sequential causal inference By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Xiaoqin Wang, Li Yin. Source: The Annals of Statistics, Volume 48, Number 1, 138--160.Abstract: In sequential causal inference, two types of causal effects are of practical interest, namely, the causal effect of the treatment regime (called the sequential causal effect) and the blip effect of treatment on the potential outcome after the last treatment. The well-known $G$-formula expresses these causal effects in terms of the standard parameters. In this article, we obtain a new $G$-formula that expresses these causal effects in terms of the point observable effects of treatments similar to treatment in the framework of single-point causal inference. Based on the new $G$-formula, we estimate these causal effects by maximum likelihood via point observable effects with methods extended from single-point causal inference. We are able to increase precision of the estimation without introducing biases by an unsaturated model imposing constraints on the point observable effects. We are also able to reduce the number of point observable effects in the estimation by treatment assignment conditions. Full Article
the The phase transition for the existence of the maximum likelihood estimate in high-dimensional logistic regression By projecteuclid.org Published On :: Mon, 17 Feb 2020 04:02 EST Emmanuel J. Candès, Pragya Sur. Source: The Annals of Statistics, Volume 48, Number 1, 27--42.Abstract: This paper rigorously establishes that the existence of the maximum likelihood estimate (MLE) in high-dimensional logistic regression models with Gaussian covariates undergoes a sharp “phase transition.” We introduce an explicit boundary curve $h_{mathrm{MLE}}$, parameterized by two scalars measuring the overall magnitude of the unknown sequence of regression coefficients, with the following property: in the limit of large sample sizes $n$ and number of features $p$ proportioned in such a way that $p/n ightarrow kappa $, we show that if the problem is sufficiently high dimensional in the sense that $kappa >h_{mathrm{MLE}}$, then the MLE does not exist with probability one. Conversely, if $kappa <h_{mathrm{MLE}}$, the MLE asymptotically exists with probability one. Full Article
the Detecting relevant changes in the mean of nonstationary processes—A mass excess approach By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Holger Dette, Weichi Wu. Source: The Annals of Statistics, Volume 47, Number 6, 3578--3608.Abstract: This paper considers the problem of testing if a sequence of means $(mu_{t})_{t=1,ldots ,n}$ of a nonstationary time series $(X_{t})_{t=1,ldots ,n}$ is stable in the sense that the difference of the means $mu_{1}$ and $mu_{t}$ between the initial time $t=1$ and any other time is smaller than a given threshold, that is $|mu_{1}-mu_{t}|leq c$ for all $t=1,ldots ,n$. A test for hypotheses of this type is developed using a bias corrected monotone rearranged local linear estimator and asymptotic normality of the corresponding test statistic is established. As the asymptotic variance depends on the location of the roots of the equation $|mu_{1}-mu_{t}|=c$ a new bootstrap procedure is proposed to obtain critical values and its consistency is established. As a consequence we are able to quantitatively describe relevant deviations of a nonstationary sequence from its initial value. The results are illustrated by means of a simulation study and by analyzing data examples. Full Article
the A smeary central limit theorem for manifolds with application to high-dimensional spheres By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Benjamin Eltzner, Stephan F. Huckemann. Source: The Annals of Statistics, Volume 47, Number 6, 3360--3381.Abstract: The (CLT) central limit theorems for generalized Fréchet means (data descriptors assuming values in manifolds, such as intrinsic means, geodesics, etc.) on manifolds from the literature are only valid if a certain empirical process of Hessians of the Fréchet function converges suitably, as in the proof of the prototypical BP-CLT [ Ann. Statist. 33 (2005) 1225–1259]. This is not valid in many realistic scenarios and we provide for a new very general CLT. In particular, this includes scenarios where, in a suitable chart, the sample mean fluctuates asymptotically at a scale $n^{alpha }$ with exponents $alpha <1/2$ with a nonnormal distribution. As the BP-CLT yields only fluctuations that are, rescaled with $n^{1/2}$, asymptotically normal, just as the classical CLT for random vectors, these lower rates, somewhat loosely called smeariness, had to date been observed only on the circle. We make the concept of smeariness on manifolds precise, give an example for two-smeariness on spheres of arbitrary dimension, and show that smeariness, although “almost never” occurring, may have serious statistical implications on a continuum of sample scenarios nearby. In fact, this effect increases with dimension, striking in particular in high dimension low sample size scenarios. Full Article
the Hypothesis testing on linear structures of high-dimensional covariance matrix By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Shurong Zheng, Zhao Chen, Hengjian Cui, Runze Li. Source: The Annals of Statistics, Volume 47, Number 6, 3300--3334.Abstract: This paper is concerned with test of significance on high-dimensional covariance structures, and aims to develop a unified framework for testing commonly used linear covariance structures. We first construct a consistent estimator for parameters involved in the linear covariance structure, and then develop two tests for the linear covariance structures based on entropy loss and quadratic loss used for covariance matrix estimation. To study the asymptotic properties of the proposed tests, we study related high-dimensional random matrix theory, and establish several highly useful asymptotic results. With the aid of these asymptotic results, we derive the limiting distributions of these two tests under the null and alternative hypotheses. We further show that the quadratic loss based test is asymptotically unbiased. We conduct Monte Carlo simulation study to examine the finite sample performance of the two tests. Our simulation results show that the limiting null distributions approximate their null distributions quite well, and the corresponding asymptotic critical values keep Type I error rate very well. Our numerical comparison implies that the proposed tests outperform existing ones in terms of controlling Type I error rate and power. Our simulation indicates that the test based on quadratic loss seems to have better power than the test based on entropy loss. Full Article
the Adaptive estimation of the rank of the coefficient matrix in high-dimensional multivariate response regression models By projecteuclid.org Published On :: Wed, 30 Oct 2019 22:03 EDT Xin Bing, Marten H. Wegkamp. Source: The Annals of Statistics, Volume 47, Number 6, 3157--3184.Abstract: We consider the multivariate response regression problem with a regression coefficient matrix of low, unknown rank. In this setting, we analyze a new criterion for selecting the optimal reduced rank. This criterion differs notably from the one proposed in Bunea, She and Wegkamp ( Ann. Statist. 39 (2011) 1282–1309) in that it does not require estimation of the unknown variance of the noise, nor does it depend on a delicate choice of a tuning parameter. We develop an iterative, fully data-driven procedure, that adapts to the optimal signal-to-noise ratio. This procedure finds the true rank in a few steps with overwhelming probability. At each step, our estimate increases, while at the same time it does not exceed the true rank. Our finite sample results hold for any sample size and any dimension, even when the number of responses and of covariates grow much faster than the number of observations. We perform an extensive simulation study that confirms our theoretical findings. The new method performs better and is more stable than the procedure of Bunea, She and Wegkamp ( Ann. Statist. 39 (2011) 1282–1309) in both low- and high-dimensional settings. Full Article
the Inference for the mode of a log-concave density By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Charles R. Doss, Jon A. Wellner. Source: The Annals of Statistics, Volume 47, Number 5, 2950--2976.Abstract: We study a likelihood ratio test for the location of the mode of a log-concave density. Our test is based on comparison of the log-likelihoods corresponding to the unconstrained maximum likelihood estimator of a log-concave density and the constrained maximum likelihood estimator where the constraint is that the mode of the density is fixed, say at $m$. The constrained estimation problem is studied in detail in Doss and Wellner (2018). Here, the results of that paper are used to show that, under the null hypothesis (and strict curvature of $-log f$ at the mode), the likelihood ratio statistic is asymptotically pivotal: that is, it converges in distribution to a limiting distribution which is free of nuisance parameters, thus playing the role of the $chi_{1}^{2}$ distribution in classical parametric statistical problems. By inverting this family of tests, we obtain new (likelihood ratio based) confidence intervals for the mode of a log-concave density $f$. These new intervals do not depend on any smoothing parameters. We study the new confidence intervals via Monte Carlo methods and illustrate them with two real data sets. The new intervals seem to have several advantages over existing procedures. Software implementing the test and confidence intervals is available in the R package verb+logcondens.mode+. Full Article
the Projected spline estimation of the nonparametric function in high-dimensional partially linear models for massive data By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Heng Lian, Kaifeng Zhao, Shaogao Lv. Source: The Annals of Statistics, Volume 47, Number 5, 2922--2949.Abstract: In this paper, we consider the local asymptotics of the nonparametric function in a partially linear model, within the framework of the divide-and-conquer estimation. Unlike the fixed-dimensional setting in which the parametric part does not affect the nonparametric part, the high-dimensional setting makes the issue more complicated. In particular, when a sparsity-inducing penalty such as lasso is used to make the estimation of the linear part feasible, the bias introduced will propagate to the nonparametric part. We propose a novel approach for estimation of the nonparametric function and establish the local asymptotics of the estimator. The result is useful for massive data with possibly different linear coefficients in each subpopulation but common nonparametric function. Some numerical illustrations are also presented. Full Article
the Exact lower bounds for the agnostic probably-approximately-correct (PAC) machine learning model By projecteuclid.org Published On :: Fri, 02 Aug 2019 22:04 EDT Aryeh Kontorovich, Iosif Pinelis. Source: The Annals of Statistics, Volume 47, Number 5, 2822--2854.Abstract: We provide an exact nonasymptotic lower bound on the minimax expected excess risk (EER) in the agnostic probably-approximately-correct (PAC) machine learning classification model and identify minimax learning algorithms as certain maximally symmetric and minimally randomized “voting” procedures. Based on this result, an exact asymptotic lower bound on the minimax EER is provided. This bound is of the simple form $c_{infty}/sqrt{ u}$ as $ u oinfty$, where $c_{infty}=0.16997dots$ is a universal constant, $ u=m/d$, $m$ is the size of the training sample and $d$ is the Vapnik–Chervonenkis dimension of the hypothesis class. It is shown that the differences between these asymptotic and nonasymptotic bounds, as well as the differences between these two bounds and the maximum EER of any learning algorithms that minimize the empirical risk, are asymptotically negligible, and all these differences are due to ties in the mentioned “voting” procedures. A few easy to compute nonasymptotic lower bounds on the minimax EER are also obtained, which are shown to be close to the exact asymptotic lower bound $c_{infty}/sqrt{ u}$ even for rather small values of the ratio $ u=m/d$. As an application of these results, we substantially improve existing lower bounds on the tail probability of the excess risk. Among the tools used are Bayes estimation and apparently new identities and inequalities for binomial distributions. Full Article