of

A systematic review and meta-analysis of bone loss in space travelers

npj Microgravity, Published online: 05 May 2020; doi:10.1038/s41526-020-0103-2

A systematic review and meta-analysis of bone loss in space travelers




of

Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity




of

Simultaneous noninvasive recording of electrocardiogram and skin sympathetic nerve activity (neuECG)




of

CRISPR off-target detection with DISCOVER-seq




of

Cellular thermal shift assay for the identification of drug–target interactions in the <i>Plasmodium falciparum</i> proteome




of

Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&amp;T-seq




of

Tissue-specific alteration of gene expression and function by RU486 and the GeneSwitch system




of

Short-term NAD<sup>+</sup> supplementation prevents hearing loss in mouse models of Cockayne syndrome




of

Repository of proposed pathways and protein–protein interaction networks in age-related macular degeneration




of

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging




of

npj Aging and Mechanisms of Disease




of

High rate of durable remissions post autologous stem cell transplantation for core-binding factor acute myeloid leukaemia in second complete remission




of

Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




of

Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




of

Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment




of

Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells




of

Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells




of

The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors




of

WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2




of

NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas




of

MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer

Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers.




of

Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




of

Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs

miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors.




of

Nanomolar-scale, high throughput chemical synthesis of drug-like molecules

A high throughput, miniaturized chemical synthesis platform could enable rapid discovery of lead compounds.




of

Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue inhibitor of metalloproteinases 3 (TIMP3)

Mouse studies suggest inhibiting PGF could help treat hypertension.




of

Neutralizing the negatives of RNAi

The siRNN technology that Solstice licensed from UCSD could take RNAi-based therapies to tissues outside the liver and expand their use to a host of new diseases.




of

Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity




of

In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states




of

Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis




of

UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53




of

The rise of integrated quantum photonics




of

Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization




of

Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation




of

An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




of

Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions




of

Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities




of

Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys




of

Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear




of

A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology




of

Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity




of

Role of long non-coding RNA in T1DM




of

Nanoscale nights of COVID-19




of

Probing nanoscale fluctuation of ferromagnetic meta-atoms with a stochastic photonic spin Hall effect




of

Listening to the sound of a bacterium




of

Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis




of

Publisher Correction: Optomechanical detection of vibration modes of a single bacterium




of

MOF water harvesters




of

Nonoperative treatment of traumatic spinal injuries in Tanzania: who is not undergoing surgery and why?




of

Incidence of acute spinal cord injury in South Korea does not reflect a sizable number of traumatic spinal cord injuries




of

A more accurate incidence of acute spinal cord injury in South Korea can be estimated by the national health insurance system