rt A portable electrochemiluminescence bipolar electrode array for the visualized sensing of Cas9 activity By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00678E, PaperRui Guo, Shanwen Hu, Zonghua WangA new type of closed BPE-ECL system based on an Au electric circuit at a portable substrate is designed for the visualized sensing of Cas9 Activity in the CRISPR/Cas9 system.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Portable surface-enhanced Raman scattering analysis performed with microelectrode-templated silver nanodendrites By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00484G, PaperJoshua Raveendran, Aristides DocoslisUsing a handheld Raman spectrometer, we demonstrate how silver nanodendritic substrates formed on microelectrode platforms can be used for ultrasensitive detection of target analytes, such as cocaine and melamine. The...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt A signal cascade amplification strategy based on RT-PCR triggering of G-quadruplex DNAzyme for a novel electrochemical detection of viable Cronobacter sakazakii By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00270D, PaperYuanyuan Yuan, Xianyong Wu, Zhanmin Liu, QIqi Ning, Liqiang Fu, Sujuan WuCronobacter sakazakii is an important opportunistic food-borne pathogen, and it can cause severe diseases with main symptoms including neonatal meningitis, necrotizing enterocolitis, and sepsis. For the achievement of practical and...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt iso-μmGene: Isothermal amplification-based portable microfluidic system for simple, reliable and flexibly multiplexed Genetic identification and quantification By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00560F, PaperRuntao Zhong, Shilin Liu, Guohao Zhang, Mengyu Wang, Yeqing SunSimple, reliable and flexibly multiplexed genetic identification and quantification of microbial pathogens is in urgent need for early disease diagnosis and timely treatment. This study presented an isothermal amplification-based portable...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Accelerated non-crosslinking assembly of DNA-functionalized nanoparticles in alcoholic solvents: for application in the identification of clear liquors By feeds.rsc.org Published On :: Analyst, 2020, 145,3229-3235DOI: 10.1039/D0AN00029A, PaperLuyang Wang, Guoqing Wang, Yali Shi, Lan Zhang, Ran An, Tohru Takarada, Mizuo Maeda, Xingguo LiangAccelerated aggregation of DNA-functionalized gold nanoparticles is discovered in alcoholic solvents upon adding full-match DNA and is potentially useful for the identification of Baijiu.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt In vitro simultaneous mapping of the partial pressure of oxygen, pH and inorganic phosphate using electron paramagnetic resonance By feeds.rsc.org Published On :: Analyst, 2020, 145,3236-3244DOI: 10.1039/D0AN00168F, PaperAkihiro Taguchi, Stephen DeVience, Benoit Driesschaert, Valery V. Khramtsov, Hiroshi HirataA simultaneous mapping method was established for the partial pressure of oxygen, pH and inorganic phosphate using electron paramagnetic resonance.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Why ammonium detection is particularly challenging but insightful with ionophore-based potentiometric sensors – an overview of the progress in the last 20 years By feeds.rsc.org Published On :: Analyst, 2020, 145,3188-3210DOI: 10.1039/D0AN00327A, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.María Cuartero, Noemi Colozza, Bibiana M. Fernández-Pérez, Gastón A. CrespoAn overview of ionophore-based electrodes for ammonium sensing critically analyzing contributions in the last 20 years and with focus in analytical applications.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Model independent peak fitting and uncertainty assignment for high-precision time-of-flight mass spectrometry By feeds.rsc.org Published On :: Analyst, 2020, 145,3401-3406DOI: 10.1039/D0AN00325E, PaperAleksey Vladimirovich Chudinov, Marco Rosenbusch, Vyacheslav Ivanovich Kozlovskiy, Valeriy Vladislavovich Raznikov, Peter Schury, Michiharu Wada, Hermann WollnikLogarithmic scale splines for smooth extraction of a native peak shape, and uncertainty estimation using direct trials.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Colorimetric identification of lanthanide ions based on two carboxylic acids as an artificial tongue By feeds.rsc.org Published On :: Analyst, 2020, 145,3359-3363DOI: 10.1039/D0AN00357C, PaperChi Zhang, Juan Huang, Wei Wei, Zhengbo ChenWe report a colorimetric array, which consists of two carboxylic acids (quinolinic acid (QA), tannic acid (TCA)) as the sensor element and Eriochrome Black T (EBT) as the colorimetric signal readout.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Nano-crystalline cellulose-coated magnetic nanoparticles for affinity adsorption of glycoproteins By feeds.rsc.org Published On :: Analyst, 2020, 145,3407-3413DOI: 10.1039/D0AN00442A, PaperJiaying Zhang, Xiangyu Feng, Jing Wang, Guozhen Fang, Jifeng Liu, Shuo WangA new core–shell structured nanomaterial based on Fe3O4 nanoparticles and 2,3-dialdehyde nanocrystalline cellulose (DAC) coatings and its high efficiency in the preconcentration of glycoproteins were described in this work.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt In situ amplified photothermal immunoassay for neuron-specific enolase with enhanced sensitivity using Prussian blue nanoparticle-loaded liposomes By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00417K, PaperLi-Juan Zhi, Ai-Li Sun, Dianping TangMethods based on prussian blue nanoparticles (PBNPs) have been reported for photothermal immunoassays in analytical nanoscience fields but most suffer from low sensitivity and are not beneficial for routine use.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Driving Force to Detect Alzheimer's Disease Biomarkers: The Application Of A Thioflavine T@Er-MOF Ratiometric Fluorescent Sensor for Smart Detection of Presenilin 1, amyloid β-protein and Acetyl Choline By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00440E, PaperXing Ze Wang, jing du, Nannan Xiao, Yan Zhang, Ling Fei, Jed D. LaCoste, Zhuo Huang, Qian wang, Xin Rui Wang, Bin DingCurrently, the highly sensitive detection of Alzheimer's Disease (AD) biomarkers, namely presenilin 1, amyloid β-protein (Aβ), and acetylcholine (ACh), are vital to helping us prevent and diagnose AD. In this...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt Portable and field-deployed surface plasmon resonance and plasmonic sensors By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00316F, Critical ReviewJean-Francois MassonPlasmonic sensors are portable devices that can be employed in situ for the detection of analytes in environmental sciences, clinical diagnostics, infectious diseases, food, and industrial applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt A paper-supported sandwich immunosensor based on upconversion luminescence resonance energy transfer for the visual and quantitative determination of a cancer biomarker in human serum By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/C9AN02307K, PaperMengyuan He, Ning Shang, Lin Shen, Zhi-hong LiuIn this paper, a paper-supported analytical device based on a sandwich immunoreaction and luminescence resonance energy transfer (LRET) was reported for the visual and quantitative determination of a cancer biomarker,...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
rt [ASAP] Facilitating Protein Expression with Portable 5'-UTR Secondary Structures in <italic toggle="yes">Bacillus licheniformis</italic> By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00355 Full Article
rt Relief for the Uncertain By feeds.christianitytoday.com Published On :: Our covenant-making, covenant-keeping Lord goes before us and he is with us. Full Article
rt [ASAP] Molecule Property Analyses of Active Compounds for <italic toggle="yes">Mycobacterium tuberculosis</italic> By feedproxy.google.com Published On :: Mon, 20 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02075 Full Article
rt [ASAP] Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties By feedproxy.google.com Published On :: Wed, 22 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00117 Full Article
rt [ASAP] Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma By feedproxy.google.com Published On :: Thu, 23 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02161 Full Article
rt [ASAP] Computational Chemistry on a Budget: Supporting Drug Discovery with Limited Resources<subtitle>Miniperspective</subtitle> By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02126 Full Article
rt [ASAP] Both <sc>d</sc>- and <sc>l</sc>-Glucose Polyphosphates Mimic <sc>d</sc>-<italic toggle="yes">myo</italic>-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00215 Full Article
rt [ASAP] Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin—Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00441 Full Article
rt [ASAP] Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00075 Full Article
rt [ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00669 Full Article
rt [ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents By feedproxy.google.com Published On :: Wed, 08 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00639 Full Article
rt [ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1 By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00131 Full Article
rt [ASAP] Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00066 Full Article
rt Construction has started on the largest solar project in Nepal By latestsolarnews.com Published On :: Tue, 01 May 2018 18:55:50 +0000 The reports say that the constructions of a 25MW largest solar PV project in Nepal has begun. The foundation stone was laid last week at Devighat in Nuwakot by Minister for Energy, Water Resources and Irrigation, Barsha Man Pun. The government plans to finish the construction of the project in a year. As stated by … The post Construction has started on the largest solar project in Nepal appeared first on LatestSolarNews. Full Article News
rt Contextual styling with custom properties By simurai.com Published On :: Sun, 01 Apr 2018 00:00:00 +0000 Something I’ve been wanting for a long time, define different regions like a footer section, or side bar and not have to deal with all the contextual styling hassle. A.k.a. “Now that this button is used on a dark background, the button needs to change its colors too. Where should the styles live?”. Here an old post about struggling with contextual styling. So then the other day I was doing some experiments with using custom properties for Atom’s UI. Turns out, using custom properties might make contextual styling a bit easier. For the rest of the post, let’s switch to a more simple example. A page where the main area is light, but then has a dark hero and footer section. Like this: In the past, I probably would’ve created variations like Button--dark or overwrote it with header .Button {…}. Depends a bit on the project. Here another approach: Create themes with a set of variables, then apply the theme to the different areas. 1. Default theme First let’s define our default theme with a bunch of variables. [data-theme="default"] { --fg: hsl(0,0%,25%); --border: hsl(0,0%,75%); --bg: hsl(0,0%,95%); --button-bg: hsl(0,0%,99%); --input-bg: hsl(0,0%,90%); } Then we create some components where we use the variables defined above. [data-theme] { color: var(--fg); background-color: var(--bg); } .Button { color: var(--fg); border: 1px solid var(--border); background-color: var(--button-bg); } .Input { color: var(--fg); border: 1px solid var(--border); background-color: var(--input-bg); } And lastly we add the [data-theme="default"] attribute on the body so that our components will pick up the variables. <body data-theme="default"> If you wonder why use data-theme attributes over classes? Well, no specific reason. Maybe with attributes, it’s a hint that only one theme should be used per element and is more separated from your other classes. At this point we get this: See the Pen Contextual styling with custom properties (1/3) by simurai (@simurai) on CodePen. 2. Dark theme But our designer wants the hero and footer to be dark. Alright, let’s define another theme region. [data-theme="dark"] { --fg: hsl(0,10%,70%); --border: hsl(0,10%,10%); --bg: hsl(0,0%,20%); --button-bg: hsl(0,0%,25%); --input-bg: hsl(0,0%,15%); } And add the theme attribute to the header and footer. <header data-theme="dark"> <footer data-theme="dark"> Which gives us this: See the Pen Contextual styling with custom properties (2/3) by simurai (@simurai) on CodePen. The reason why this works is that custom properties cascade and can be overridden on nested elements, just like normal properties. 3. Hero theme A few months pass and our designer comes back with a redesigned hero section. “To make it look fresh” with a splash of color. No problem! Just like with the dark theme, we define a new “hero” theme. [data-theme="hero"] { --fg: hsl(240,50%,90%); --border: hsl(240,50%,10%); --bg: hsl(240,33%,30%); --button-bg: hsl(240,33%,40%); --input-bg: hsl(240,33%,20%); } <header data-theme="hero"> And here is that fresh hero: See the Pen Contextual styling with custom properties (3/3) by simurai (@simurai) on CodePen. It’s also not limited to colors only, could be used for sizes, fonts or anything that makes sense to define as variables. Benefits Using these theme “regions” lets your components stay context un-aware and you can use them in multiple themes. Even on the same page. Developers can add components, move components around, without having to know about in what context (theme) they live. The markup for the components stays the same. Design systems authors can create new components without worrying about where they get used, the variables used in components stay the same. Designers can define new theme regions, or change existing ones, without having to make changes to a component’s HTML or CSS, it stays the same. Less time to talk about who, how and where, more time to talk about the weather. ☔️???? Concerns Yeah, right. The big question: But does it scale? Can this be used for all use cases. Ok, I’m pretty sure it doesn’t fit all situations. There are just too many to find a single solution for them all. And I’m actually not sure how well it scales. I guess it works great in these simple demos, but I have yet to find a larger project to test it on. So if you have used (or plan to use) this approach, I’m curious to know how it went. A concern I can imagine is that the list of variables might grow quickly if themes have totally different characteristics. Like not just a bit darker or lighter backgrounds. Then you might need to have foreground and border colors for each component (or group of components) and can’t just use the general --fg and --border variables. Naming these variables is probably the hardest part. Update I @giuseppegurgone made an interesting comment: in suitcss projects I used to define component level custom props, theme variables and then create themes by mapping the former to the latter suitcss-toolkit So if I understood it correctly, by mapping theme variables to component variables, you could avoid your theme variables from growing too much and you can decide for each component how to use these theme variables. Update II If it’s too early to use custom properties in your project, @szalonna posted an example how to do something similar in SCSS. Full Article
rt Thanks to Covid-19, Website Accessibility Has Never Been More Important By www.webdesignerdepot.com Published On :: Thu, 07 May 2020 10:45:59 +0000 The first global pandemic of the digital era is upon us. We’re living in unprecedented and uncomfortable times. For our senior citizens, these past several weeks have been particularly discomforting. According to the CDC, men and women over the age of 65 are significantly more likely to develop complications from COVID-19. As we seek to […] Full Article Interactive Design a11y design for seniors older web users web design for elderly website accessibility
rt The matter of photography in the Americas / Natalia Brizuela and Jodi Roberts ; with contributions by Lisa Blackmore, Amy Sara Carroll, Marianela D'Aprile, María Fernanda Domínguez, Heloisa Espada, Rachel Price, Diana Ruiz, Tatiane Santa Ro By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - TR184.B75 2018 Full Article
rt How art can be thought: a handbook for change / Allan deSouza By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N7425.D459 2018 Full Article
rt Library of light: encounters with artists and designers / Jo Joelson By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N8219.L5 J64 2019 Full Article
rt Mathias Goeritz: modernist art and architecture in Cold War Mexico / Jennifer Josten By library.mit.edu Published On :: Sun, 16 Feb 2020 06:00:01 EST Rotch Library - N6559.G64 J67 2018 Full Article
rt Djordje Ozbolt: regaining memory loss / exhibition curator, Nicoletta Lambertucci By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 Y8 Full Article
rt New design, neoplasticism: Nieuwe beelding / Piet Mondrian ; English translation by Harry Holtzman and Martin S. James By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6948.5.D42 M6613 2019 Full Article
rt Art for people's sake: artists and community in Black Chicago, 1965-1975 / Rebecca Zorach By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - NX512.3.A35 Z67 2019 Full Article
rt It's about time: Pavilion of Applied Arts / curator, Ralph Rugoff ; artist, Marysia Lewandowska By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A67 Full Article
rt Altered states: Substanzen in der zeitgenössischen Kunst = substances in contemporary art / herausgegeben von = edited by Milena Mercer ; Texte = texts, Max Daly ... [and thirteen others] By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8251.S555 A48 2018 Full Article
rt Women, art and money in late Victorian and Edwardian England: the hustle and the scramble / Maria Quirk By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N8354.Q57 2019 Full Article
rt Neuer Norden Zürich: ein Kunstprojekt im öffentlichen Raum, 9. Juni-2. September 2018 = New north Zurich: a public art project, 9th of June-2nd of September 2018 / herausgegeben von Christoph Doswald ; fotografiert von Pierluigi Macor ; Übe By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6496.3.S9 Z876 2018 Full Article
rt Fogo Island arts: what do we know? What do we have? What do we miss? What do we love? / Brigitte Oetker, Nicolaus Schafhausen (eds.) By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6546.N6 F64 2019 Full Article
rt Raoul de Keyser: oeuvre / editors, Martin Germann and Bernhart Schwenk By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - ND673.K396 A4 2019 Full Article
rt April in Paris: theatricality, modernism, and politics at the 1925 Art Deco Expo / Irena R. Makaryk By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Hayden Library - N6493 1925.M35 2018 Full Article
rt New life quarterly / Wolfman By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Hayden Library - NX60.N49 2018 Full Article
rt Biennale Arte 2019: may you live in interesting times: 11.05-24.11 Venezia Giardini/Arsenale By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 A1 Full Article
rt Saules: Suns / artist = māksliniece, Daiga Grantin̦a ; curators = kuratori, Valentinas Klimašauskas, Inga Lāce By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 L35 Full Article
rt Padiglione Indonesiano all Biennale di Venezia 2019 / team artistico, Syagini Ratna Wulan, Handiwirman Saputra, artisti ; Asmudjo J. Irianto, Yacobus Ari Respati, curatore By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 I5 Full Article
rt Socially engaged art and the neoliberal city / Cecilie Sachs Olsen By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N72.A76 O47 2019 Full Article
rt Conversation pieces: the world of Bruegel / Abdelkader Benali, Alexandra van Dongen, Katrien Lichtert, Sabine Pénot, Lucinda Timmermans ; translation, Patrick Lennon, Michael Lomax By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - ND673.B73 B46 2018 Full Article