Biomater. Sci., 2024, 12,1788-1800
DOI: 10.1039/D4BM00034J, Paper

Jingjing Cheng, Haixin Zhang, Kunyan Lu, Yi Zou, Dongxu Jia, Hong Yang, Hong Chen, Yanxia Zhang, Qian Yu
A bi-functional antibiofilm nanoplatform was developed based on a complex of quercetin and copper integrating bactericidal and anti-quorum sensing properties.
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Biomater. Sci., 2024, 12,1871-1882
DOI: 10.1039/D3BM01922E, Paper

Meng Zhang, Hongjin Xue, Jiaxin Yang, Xin Zhao, Mei Xue, Wei Sun, Jianfeng Qiu, Zhihong Zhu
A Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu²⁺ and Vc-Ca to achieve improved chemodynamic therapy via H₂O₂ self-supply and GSH depletion.
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Biomater. Sci., 2024, 12,1822-1840
DOI: 10.1039/D3BM01931D, Paper

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Robert J. Cavanagh, Patrícia F. Monteiro, Cara Moloney, Alessandra Travanut, Fatemeh Mehradnia, Vincenzo Taresco, Ruman Rahman, Stewart G. Martin, Anna M. Grabowska, Marianne B. Ashford, Cameron Alexander
Combinations of the topoisomerase II inhibitor doxorubicin and the poly (ADP-ribose) polymerase inhibitor olaparib offer potential drug–drug synergy for treatment of triple negative breast cancers (TNBC) both in free drug form and when delivered by oxidation-responsive nanoparticles.
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Biomater. Sci., 2024, 12,1617-1629
DOI: 10.1039/D3BM01894F, Review Article

Mengjun Huang, Qiliang Teng, Fei Cao, Jinsheng Huang, Jun Pang
Existing treatments could be sensitized by targeting the ferroptosis pathway in prostate cancer.
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Biomater. Sci., 2024, 12,1864-1870
DOI: 10.1039/D3BM01994B, Paper

Yongzhi Chen, Qiuxia Tan, Yuanyu Tang, E. Pang, Rui Peng, Minhuan Lan, Dousheng Bai
Hepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality.
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Biomater. Sci., 2024, 12,1761-1770
DOI: 10.1039/D3BM02035E, Paper

Hao Deng, Yuheng Jiang, Junhao Deng, Feifan Chang, Junyu Chen, Xinyu Sun, Dongliang Cheng, Zhongqi Wang, Ran Li, Jiang Liu, Yi Li, Licheng Zhang, Pengbin Yin
Extracellular vesicles (EVs) produced by 3D-cultured MSCs can modulate macrophage activation through ANXA1, thereby promoting wound healing.
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Biomater. Sci., 2024, 12,1924-1931
DOI: 10.1039/D3BM01926H, Paper

Xiaoke Zhang, Qianwen Yang, Sensen Zhou, Cheng Li, Xiqun Jiang
A H₂O₂-sensitive macromolecular optical probe which can effectively bind to collagen was developed for real time noninvasive visualization of fibrotic tissues.
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Biomater. Sci., 2024, 12,1771-1787
DOI: 10.1039/D3BM01150J, Paper

Jin Teng Chung, Mehrnoosh Rafiei, Ying Chau
Antigens are delivered in self-adjuvanted arginine-modified dextran-based nanogels to the dendritic cells in promoting antigen specific cellular immunity.
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Biomater. Sci., 2024, 12,1801-1821
DOI: 10.1039/D3BM01688A, Paper

Manju Sharma, Samraggi Choudhury, Anand Babu, Varun Gupta, Dipanjan Sengupta, Syed Afroz Ali, Mrunali D. Dhokne, Ashok Kumar Datusalia, Dipankar Mandal, Jiban Jyoti Panda
The graphical abstract portraying the utility of peizoactive polydopamine-coated PVDF nanospheres as potential therapeutic modalities for Alzheimer's disease. The nanospheres induced fibril disaggregation and neuroprotection upon acoustic activation in neural cells and animal model.
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Biomater. Sci., 2024, 12,1914-1923
DOI: 10.1039/D3BM01675G, Paper

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Pei Wei, Lijiao Wu, Hongteng Xie, Zhaohong Chen, Rongwei Tan, Zhaorong Xu
A novel meshed ADS combined with NPWT can reduce the risk of scaffold-related complications, which helps to improve the quality of wound repair and promotes a broader range of applications.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01338C, Review Article

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Adam Shearer, Matthew Molinaro, Maziar Montazerian, Jessica J. Sly, Marta Miola, Francesco Baino, John C. Mauro
Alkali and alkaline earth elements play a crucial role in the structure, processing, and properties of bioactive glasses, widely used in medical applications since their inception in 1969.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00061G, Paper

Hang Ren, Peng Wang, Hanwen Huang, Junshen Huang, Yuheng Lu, Yanfeng Wu, Zhongyu Xie, Youchen Tang, Zhaopeng Cai, Huiyong Shen
Modified Ti with a porous N-halaminated spermidine-containing polymeric coating is constructed, and it has both excellent antibacterial and osteogenic abilities to enhance osseointegration, making it potentially applicable in orthopedics.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00155A, Review Article

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Yungang Hu, Lu Yu, Qiang Dai, Xiaohua Hu, Yuming Shen
Due to their distinctive physical and chemical properties as well as their biological functionalities, multifunctional antibacterial hydrogels possess significant advantages in the treatment of chronic wounds.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00003J, Paper

Jing Liu, Jie Zhang, Yongteng Zhang, Wei Wei, Meixiao Zhan, Zhiren Zhang, Bing Liu, Xianglong Hu, Weiling He
Facile conjugation of chlorambucil with IR775 chloride can afford IR775-Cbl with mitochondria-targeting potency for tumor cells, exhibiting distinct “1 + 1 > 2” tumor inhibition.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01900D, Paper

Veronika Sarnatskaya, Yuliia Shlapa, Denis Kolesnik, Olexandra Lykhova, Dmytro Klymchuk, Serhii Solopan, Svitlana Lyubchyk, Iuliia Golovynska, Junle Qu, Yurii Stepanov, Anatolii Belous
Nano-dispersed cerium dioxide is promising for use in medicine due to its unique physicochemical properties, low toxicity, the safety of in vivo usage, active participation in different redox processes occurring in living cells, and its regenerative potential.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90027H, Correction

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Safieh Boroumand, Faraz Sigaroodi, Seyed Mohsen Ahmadi Tafti, Keyvan Khoshmaram, Masoud Soleimani, Mohammad-Mehdi Khani
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90029D, Correction

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Ee Taek Hwang, Yeahwa Yoon, Ka Ram Kim, Chan Hee Lee, Kyung Chan Jeon, Ji Ho Min, Jae Won Lee, Jangyong Kim
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90028F, Correction

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Keqin Ji, Mingrui Fan, Dong Huang, Lingna Sun, Bingqin Li, Ruoting Xu, Jiajing Zhang, Xuan Shao, Yanzuo Chen
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00357H, Paper

Bin Zhang, Rui Yang, Hongwei Yu, Yamin Peng, Haoyu Huang, Meera Moydeen Abdul Hameed, Han Wang, Guixiang Zhang, Mohamed EL-Newehy, Mingwu Shen, Xiangyang Shi, Shaojun Peng
Macrophage membrane-camouflaged nanoclusters of ultrasmall iron oxide nanoparticles can be developed to cross the blood–brain barrier for magnetic resonance imaging and chemo/chemodynamic therapy.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00158C, Paper

Yiduo Chen, Yirong Guo, Xinyi Li, Yanchen Chen, Jiarong Wang, Honglin Qian, Jing Wang, Youxiang Wang, Xinyang Hu, Jian'an Wang, Jian Ji
Three surface-initiated hydrogel coatings (pMPC, pAMPS, pHEMA) are constructed on polymeric heart valves. The zwitterionic pMPC coating displays optimal performances, including durable anti-coagulation, anti-inflammation, and anti-calcification.
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Biomater. Sci., 2024, 12,2041-2056
DOI: 10.1039/D3BM01674A, Paper

David A. McBride, James S. Wang, Wade T. Johnson, Nunzio Bottini, Nisarg J. Shah
The study develops a computational framework to model factors that lead to the evolution of autoreactive T cells in inflammatory arthritis. The results provide a tool for planning immunomodulatory strategies focused on new disease-modifying agents.
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Biomater. Sci., 2024, 12,2121-2135
DOI: 10.1039/D3BM01901B, Paper

Ruideng Wang, Xi He, Zhengyang Chen, Shilong Su, Jinwu Bai, Haifeng Liu, Fang Zhou
A photo-crosslinked nanocomposite hydrogel was prepared by incorporating an osteo-inductive inorganic nanoparticle for endogenous bone regeneration.
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Biomater. Sci., 2024, 12,1981-2006
DOI: 10.1039/D3BM01841E, Review Article

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Ali Zareein, Mina Mahmoudi, Shruti Sunil Jadhav, Joel Wilmore, Yaoying Wu
Biomaterials enhance B cell immunity by modulating the delivery approach, crosslinking B cell receptors, and promoting T cell help, while inhibitory co-receptor engagement via biomaterial design suppresses B cell function.
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Biomater. Sci., 2024, 12,2096-2107
DOI: 10.1039/D4BM00125G, Paper

Yimeng Zhao, Xuefei Lv, Yu Chen, Chen Zhang, Di Zhou, Yulin Deng
Neuroinflammatory response on a novel combinatorial cell–cell interaction chip.
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Biomater. Sci., 2024, 12,2019-2032
DOI: 10.1039/D3BM02070C, Review Article

Zheng Wang, Zilong Chen, Zhenhao Zhang, Hongzhen Wang, Haichang Zhang
Organic fluorescent materials (OFMs) play a crucial role in the development of biosensors, enabling the extraction of biochemical information within cells and organisms, extending to the human body.
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Biomater. Sci., 2024, 12,1943-1949
DOI: 10.1039/D3BM02008H, Minireview

Yang Song
Biological liquid–liquid phase separation (LLPS) provides novel insights for the assembly of biomaterials with tailored structure and intrinsic functionality.
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Biomater. Sci., 2024, 12,2067-2085
DOI: 10.1039/D3BM01466E, Paper

Akansha Dixit, Aman Mahajan, Rakshita Saxena, Saptomee Chakraborty, Dhirendra S. Katti
In this study, we combined the β-sheet mediated self-stiffening ability of silk with growth factor presenting ability of sulphated carboxymethyl cellulose in an injectable interpenetrating network hydrogel for repair of articular cartilage defects.
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Biomater. Sci., 2024, 12,2136-2148
DOI: 10.1039/D3BM01912H, Paper

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Edina Sehic, Lucía de Miguel Gómez, Hardis Rabe, Emy Thorén, Ingigerdur Gudmundsdottir, Mihai Oltean, Randa Akouri, Mats Brännström, Mats Hellström
Innovative bioengineering strategies utilizing extracellular matrix (ECM) based scaffolds derived from decellularized tissue offer new prospects for restoring damaged uterine tissue.
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Biomater. Sci., 2024, 12,2033-2040
DOI: 10.1039/D4BM00004H, Review Article

Yifan Zheng, Yudi Du, Ling Chen, Wei Mao, Yuan Pu, Steven Wang, Dan Wang
Shape memory polymers (SMPs), which initiate shape transformation in response to environmental stimuli, have attracted significant attention in both academic research and technological innovation.
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Biomater. Sci., 2024, 12,2057-2066
DOI: 10.1039/D3BM02071A, Paper

Song Lin, Houjin Jing, Xiaojiao Du, Xianzhu Yang, Jun Wang
A siRNA delivery system was developed using clinically approved mPEG-b-PLGA, cationic lipid and ionizable lipid for siRNA delivery and cancer immunotherapy.
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Biomater. Sci., 2024, 12,2149-2164
DOI: 10.1039/D3BM01911J, Paper

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Sofia F. Melo, Alicia Nondonfaz, Abdelhafid Aqil, Anna Pierrard, Alexia Hulin, Céline Delierneux, Bartosz Ditkowski, Maxime Gustin, Maxime Legrand, Bibian M. E. Tullemans, Sanne L. N. Brouns, Alain Nchimi, Raoul Carrus, Astrid Dejosé, Johan W. M. Heemskerk, Marijke J. E. Kuijpers, Jan Ritter, Ulrich Steinseifer, Johanna C. Clauser, Christine Jérôme, Patrizio Lancellotti, Cécile Oury
Non-isocyanate polyurethanes (NIPUs) were developed and tested in vitro. Prosthetic heart valves made of NIPU were designed and manufactured. NIPUs showed low thrombogenicity and the produced valves performed well in terms of hydrodynamics.
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Biomater. Sci., 2024, 12,2167-2167
DOI: 10.1039/D4BM90023E, Retraction

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Tao Li, Hongtao He, Zezheng Yang, Junjie Wang, Yuxin Zhang, Guangxu He, Jun Huang, Deye Song, Jiangdong Ni, Xiaojun Zhou, Junfeng Zhu, Muliang Ding
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Biomater. Sci., 2024, 12,2165-2166
DOI: 10.1039/D4BM90022G, Correction

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Yinjie Wang, Zhenqi Jiang, Bo Yuan, Yuchen Tian, Lingchao Xiang, Yanying Li, Yong Yang, Juan Li, Aiguo Wu
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM02017G, Review Article

Zhiwei Xu, Bingbing Wang, Ruoyu Huang, Mengyao Guo, Di Han, Lan Yin, Xiaoyun Zhang, Yong Huang, Xiaoming Li
Repair of bone defects exceeding critical size has been always a big challenge in clinic. Tissue engineering has exhibited great potentials to effectively repair the defects with less adverse effect...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00048J, Review Article

Hewan Dawit, Yuewu Zhao, Jine Wang, Renjun Pei
The brain-computer interface (BCI) allows the human or animal brain to direct interact with the external environment through the neural interfaces, thus playing the role of monitoring, protecting, improving/restoring, enhancing,...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00319E, Review Article

Minzi Ju, Lu Yang, Guowei Wang, Feng Zong, Yu Shen, Shuangshuang Wu, Xuna Tang, Decai Yu
Photodynamic therapy (PDT) is a minimally invasive therapeutic modality employed for the treatment of various types of cancers, localized infections, and other diseases. Upon illumination, the photo-excited photosensitizer generates singlet...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00164H, Paper

Wenmo Zhang, Runze Zhang, Rong Yang, Yage Sun, Qian Zhang, Xuequan Feng, Chunyan Cui, Wenguang Liu
Intestine damage is an acute abdominal disease that usually requires emergency sealing. However, traditional surgical suture not only causes secondary damage to the injured tissue, but also results in adhesion...
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00412D, Paper

Hao Fu, Yongxin Zhang, Cheng Wang, Zhencheng Sun, Shuyi Lv, Minghui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu
A universal strategy is developed to remarkably enhance the photothermal conversion efficiency of photothermal materials. This advancement enables effective treatment of drug-resistant bacterial infections through safe photothermal therapy.
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM02074F, Paper

Yanzhi Dong, Jiaojiao Wang, Ting Zhou, Jinbing Pan, Xu Wang, Shao-Kai Sun
We developed ultrasmall catechol-PEG-anchored ferrite nanoparticles for highly sensitive MRA. The probe enables the diagnosis of carotid artery stenosis and subsequent evaluation of reperfusion through a single injection.
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM01687K, Review Article

Xuan Wang, Fushuang Liu, Tianyi Wang, Yikai He, Yongwen Guo
Epidemiological studies reveal that symptoms of TMD occur in 60-70% of adults. The inflammatory damage caused by TMD can easily lead to defects in the articular disc, condylar cartilage, subchondral...
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM90033B, Correction

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Ya Liu, Yajun Xu, Ying Wang, Jianlin Lv, Kun Wang, Zhaohui Tang
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00289J, Paper

Rui Ding, Pandi Peng, Jingjing Huo, Kun Wang, Pengxiang Liu, Hanxue Wu, Likun Yan, Peng Li
This work demonstrates that CT coatings would be a promising material against implant-related infection in a pH-responsive manner including but not limited to the field of hernioplasty.
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00313F, Review Article

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Hana Cho, Kang Moo Huh, Hyun Ji Cho, Bogeon Kim, Min Suk Shim, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Young Jik Kwon, Han Chang Kang
Various strategies in the microscale/nanoscale have been developed to improve oral absorption of therapeutics. Among them, gastrointestinal (GI)-transporter/receptor-mediated nanosized drug delivery systems (NDDSs) have drawn attention due to their many...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00214H, Review Article

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Xin-Gui Li, Junjian Li, Jinfeng Chen, Liangmei Rao, Libin Zheng, Fei Yu, Yijing Tang, Jie Zheng, Jie Ma
Covalent organic frameworks (COFs) constitute a class of highly functional porous materials characterized by ordered structures, high crystallinity, and a substantial specific surface area, primarily composed of light atoms such...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00099D, Paper

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Maya Rima, Christina Villeneuve-Faure, Marvine Soumbo, Fatima El Garah, Ludovic Pilloux, Christine Roques, Kremena Makasheva
The interaction of foreign implants with its surrounding environment is significantly influenced by the adsorption of proteins on the biomaterial surfaces, playing role in the microbial adhesion. Therefore, understanding protein...
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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00107A, Paper

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Lesley Trask, Niamh A. Ward, Ruth Tarpey, Rachel Beatty, Eimear Wallace, Joanne O'Dwyer, William Ronan, Garry P. Duffy, Eimear B. Dolan
Implantable medical devices that can facilitate therapy transport to localized sites are being developed for a number of diverse applications, including the treatment of diseases such as diabetes and cancer,...
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Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00035H, Paper

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Woojin Back, Jiyun Rho, Kyungsu Kim, Hwan Seok Yong, Ok Hwa Jeon, Byeong Hyeon Choi, Hyun Koo Kim, Ji-Ho Park
We report the development of an injectable hydrogel-based dual computed tomography (CT) and near-infrared (NIR) imaging marker for use in preoperative pulmonary localization and intraoperative dual-imaging of deep-seated nodules.
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