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Swatantrya Veer Savarkar Review

With the kind of money and talent that has gone into making this movie, a really good biopic of a personality like Savarkar could be made.But this film is lost in polemics, as is the case with almost every biopic and period drama today, observes Utkarsh Mishra.





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Gaanth Chapter 1: Jamnaa Paar Review

It introduces random characters, goes on several wild goose chases and is incapable of holding onto any thread of the plot, sighs Deepa Gahlot.




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PM Modi, Kejriwal extend birthday wishes to Punjab CM Bhagwant Mann




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Sri Lanka hires South African consultant coach

Neil McKenzie’s playing career highlights included sharing a 415-run stand with Graeme Smith against Bangladesh in 2008




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Deshwal powers Jaipur Pink Panthers with 19-point performance against Bengaluru Bulls

Arjun Deshwal scored 19 points for the two-time PKL champions, with the second-highest scorer for the Jaipur Pink Panthers being Lucky Sharma




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25 venues in Thiruvananthapuram for State School Arts Festival

Nearly 15,000 students will participate in 249 competitive events at fete that will be held from January 4 to 8




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As UPPSC aspirants protest for 2nd day, U.P. govt. faces flak

Thousands of youth are protesting outside the UPPSC headquarters in Prayagraj against the conduct of Civil Services (preliminary), Review Officer/Assistant Review Officer examination in multiple shifts and against normalisation of score. UPPSC argues when exams are held on multiple days or shifts for a single recruitment notification, the score normalisation process is essential in evaluating the results as the difficulty level of the paper in each shift/day varies.




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Nilakanta Sastri’s take on Dravidian-Aryan divide and the claims on the Indus Valley Civilisation

In his lectures at Patna University in 1964, Sastri quotes J. Burrow, Professor of Oxford University, who had suggested that “Vedic speech was influenced not by the Dravidian languages of history as we know them, but by an earlier form, a sort of proto-Dravidian, which has long preceded them as well as Aryan advent into India”




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Cantonment MLA pushes for merger with GHMC




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Reining in civil servants in Kerala

Recent incidents highlight the importance of official channels in resolving issues




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Elephant, calf found dead at Thenkara




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Booker Prize 2024: British writer Samantha Harvey wins for space-station novel 'Orbital'

She called the book a “space pastoral” about six astronauts circling the Earth, which she began writing during COVID-19 pandemic lockdowns




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Non-bailable warrant issued against former BJD MP in connection with 2010 murder case

BJD leader N. Bhaskar Rao and five others are linked to the murder of a tribal leader in 2010




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Morning Digest: British writer Samantha Harvey’s space-station novel ‘Orbital’ wins Booker Prize for fiction; Big names face test as Jharkhand votes in Phase I, and more

Here is a select list of stories to start the day




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Assistant Commissioner is empowered to seek bank guarantee for release of vehicles seized in cow slaughter Act case, says court





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How can Sushant be gone?

'You were looking for perfection in an incurably imperfect world,' mourns Subhash K Jha who knew Sushant Singh Rajput well.





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Remembering my conversations with Sushant

'I once thought Shah Rukh Khan to be the most knowledgeable actor in our industry,' Paresh Rawal once told me.'But Sushant was just as well-informed on any topic under the sun.'Subhash K Jha recalls his many conversations with the actor.




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Only if Sushant had believed his lines from Chhichhore

'Isn't 11.3 million Instagram followers and 1.9 million Twitter followers enough to make you feel wanted and loved as a successful star?' 'Can a huge bank balance, a fleet of fancy cars, and a big house assure you happiness and contentment in life?' 'For Sushant, it did not.'







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Badhaai Do Is A Giant Step Forward

Two men smiling, eyeing each other as they briefly let their guard down, with no care of what the world around them is thinking, that has almost never been shown in a Bollywood film, notes Aseem Chhabra.




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Who Says Animal Is Anti-Women?

Be it Kabir Singh or Ranvijay Singh, alpha males are nothing but grown men in diapers, observes Durba Dhyani.




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Why Sahir Ludhianvi Is Relevant Today

While the country is gripped by Ram Mandir frenzy, Danish Husain -- without shouting from the rooftops -- silently staged his opinion with this play on one of India's best-known poets, observes Neeta Kolhatkar.




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Sit Down Servant, Sit Down

Much can be said about this song’s sacred and secular connotations. At first glance, one might assume that the song speaks to its religious roots; however, given the environment in which the song was created, the song can be taken literally. Taken from The Colonial Williamsburg Foundation’s enhanced CD, From Ear to Ear, and adapted from field recordings by John and Alan Lomax, this song was known to have been sung by the 1871 Fisk University Jubilee Singers.




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A Numerous and Brilliant Assembly: A Colonial Williamsburg Musical Sampler

Selected performances from nine of Colonial Williamsburg's recordings, including fife and drum marches, chamber music, slave chants, and tavern songs.




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To curb antimicrobial resistance, government may include antibiotics in definition of new drug

If brought into the new drug bracket, manufacturing, marketing and sale of antibiotics will be documented; patients will be able to buy antibiotics on prescription only




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Thiruvananthapuram observatory captures stunning images of rare comet C/2023 A3

Although the comet was closest to Earth on October 12, the inclement weather in Thiruvananthapuram hindered observations on that day




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What do the Atlantic Ocean hurricane forecasts foretell for India?

Climate models forecast cyclones indirectly, based on metrics that indicate cyclonic activity and its potential intensity




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Ancient meteorite was 'giant fertiliser bomb' for life on earth

The meteorite would have delivered a large amount of phosphorous, a nutrient for microbes crucial for the molecules central to storing and conveying genetic information.




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RRI team use quantum magnetometry to make more precise atomic clocks




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Stem cell transplant recipients demystify the fate of donated stem cells




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Study finds long-term dynamics of transplanted stem cells




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Why Cambodia’s novel H5N1 reassortant virus needs close monitoring

All available data suggest human infections caused by the reassortant virus are attributed to direct poultry-to-human transmission, with no evidence of human-to-human spread




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Panel on education policy wants UGC Act to lapse

The committee's report, submitted recently to the HRD Ministry, says the UGC has been unable to effectively implement its regulations.




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Twin advantage at University of Southampton

Hemanth Iyappa Guddanda writes about his exciting stints at the university's Malaysia and the U.K. campuses.




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Want number of Indian students in France to climb to 20,000 by 2025: French Minister

French Minister Catherine Colonna stressed that gender balance was a necessity in the field of education




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CUET-UG not to make board exams redundant, says UGC Chairman Jagadesh Kumar

UGC Chairman Jagadesh Kumar emphasises that board exams are not likely to be made irrelevant in light of the decline in pass percentage in CBSE class 12 exams this year




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Want to be a work traveller?

Co-working is the new watchword of the creative young. An affordable lifestyle and low rents make Berlin their preferred destination.Shonali Muthalaly




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Get a bite with Bitcoin: Bangalore restaurant now accepts payment in Bitcoins

Suryawanshi in Bengaluru is the second restaurant in the country to have started accepting bitcoins.




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Bharatiya Anthariksh Station: India To Have Its Space Station, Announces PM Modi

The Union Cabinet today approved the first step towards the Bharatiya Antariksh Station.




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Poignant narratives

Important episodes from the Ramayana were presented at a three-day Kathakali festival in Ambalappuzha.




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Sindhu Trade Links Limited - Board Meeting Intimation for To Consider And Approve The Unaudited Financial Results (Consolidated) IND -AS Compliant Of The Company For The Quarter Ended On 30Th June, 2019




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Paul Merchants Ltd - Standalone As Well As Consolidated Un-Audited Financial Results Alongwith Segment Results For The Quarter Ended June 30, 2019 Along With Limited Review Report Issued By Statutory Auditors Of The Company




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Sonal Mercantile Ltd - Board Meeting Intimation for To Consider And Approve (Standalone As Well As Consolidated) Un-Audited Financial Results Of The Company For The Quarter Ended June 30, 2019




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Pacheli Industrial Finance Ltd - Board Meeting Intimation for Intimation Of The Board Meeting To Be Held On August 14Th, 2019 For Approval Of Financial Results Pursuant To Regulation 29(1)(A) Of The SEBI (Listing Obligation And Disclosure Requirements) Re




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Directed evolution of C-methyltransferase PsmD for enantioselective pyrroloindole derivative production

Catal. Sci. Technol., 2024, 14,6298-6306
DOI: 10.1039/D4CY00657G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Diana A. Amariei, Julia Tenhaef, Thomas Classen, Benoit David, Tobias M. Rosch, Holger Gohlke, Stephan Noack, Jörg Pietruszka
The engineering of stereoselective C-methyltransferase PsmD through saturation mutagenesis led to improved activity for larger substrates. An automated process was designed and successfully applied for the mutant library production and screening.
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