ed

Chemistry breakthrough could speed up drug development

Scientists have successfully developed a new technique to reliably grow crystals of organic soluble molecules from nanoscale droplets, unlocking the potential of accelerated new drug development.




ed

Hydrogen blamed for interfering with nickelate superconductors synthesis

Prof. ZHONG Zhicheng's team at the Ningbo Institute of Materials Technology and Engineering has investigated the electronic structure of the recently discovered nickelate superconductors NdNiO2. They successfully explained the experimental difficulties in synthesizing superconducting nickelates, in cooperation with Prof. Karsten Held at Vienna University of Technology.




ed

The Lancet: New triple antiviral drug combination shows early promise for treating COVID-19 in phase 2 randomized trial

A two-week course of antiviral therapy with interferon beta-1b plus lopinavir-ritonavir and ribavirin, started within 7 days of showing COVID-19 symptoms, is safe and more effective at reducing the duration of viral shedding than lopinavir-ritonavir alone in patients with mild to moderate illness, according to the first randomized trial of this triple combination therapy involving 127 adults (aged 18 and older) from six public hospitals in Hong Kong.




ed

Discovered a multilayer haze system on Saturn's Hexagon

The most extensive system of haze layers ever observed in the solar system have been discovered and characterised on the planet Saturn.




ed

Epithelial GPS: Position of RNAi machinery is associated with epithelial identity

Researchers at the Medical University of South Carolina show in a new report that the RNA interference machinery, normally thought to reside in the nucleus or cytoplasm, predominantly localizes to these apical junctions and influences cell biology in the colon. Interestingly, in colon tumors, this localization is dysregulated and may shift the balance of RNAs to promote tumorigenesis.




ed

Plasma medicine research highlights antibacterial effects and potential uses

As interest in the application of plasma medicine -- the use of low-temperature plasma (LTP) created by an electrical discharge to address medical problems -- continues to grow, so does the need for research advancements proving its capabilities and potential impacts on the health care industry. Across the world, many research groups are investigating plasma medicine for applications including cancer treatment and the accelerated healing of chronic wounds, among others.




ed

To climb like a gecko, robots need toes

Researchers know the secret to geckos' ability to walk on the ceiling: their hairy toes. But how do they use their five toes per foot to adjust to gravity when running horizontally along walls. At UC Berkeley, biologists used high-speed cameras to record how geckos orient their toes with shifting weight, especially when encountering slippery or rough patches, and found a remarkable ability to adjust toe orientation to stick and peel while running full speed.




ed

Individualized mosaics of microbial strains transfer from the maternal to the infant gut

Researchers have used a microbiome 'fingerprint' method to report that an individualized mosaic of microbial strains is transmitted to the infant gut microbiome from a mother giving birth through vaginal delivery. They detailed this transmission by analyzing existing metagenomic databases of fecal samples from mother-infant pairs, as well as analyzing mouse dam and pup transmission in a germ-free, or gnotobiotic, mouse model, where the dams were inoculated with human fecal microbes.




ed

Pediatric coronavirus disease (COVID-19) x-ray, CT in review of new lung disorders

Although the clinical symptoms of SARS, H1N1, MERS, EVALI, and COVID-19 may be nonspecific, some characteristic imaging findings are emerging, says the American Journal of Roentgenology (AJR). Careful evaluation of the distribution, lung zone preference, and symmetry of the abnormalities with an eye for a few unique differentiating imaging features can allow radiologists to offer a narrower differential diagnosis in pediatric patients, leading to optimal patient care.




ed

'Detailed' plans being drawn up to restart economy, Jenrick says as testing falls below 100,000 for fourth day

The update comes after Prime Minister Boris Johnson confirmed he would set out a lockdown exit strategy on Sunday.




ed

Debenhams accused of 'stealing' as retailer demands 90% discount on clothes from suppliers already at UK ports

ITV News has seen correspondence from Debenhams’ administrator to Bangladeshi suppliers demanding a 90% discount on garments orders.




ed

Hospices still denied access to PPE as Health Secretary insists government is doing 'as much as we can'

One hospice ITV News spoke to is three days away from running out of protective gowns needed to treat patients with coronavirus.




ed

Kraftwerk co-founder Florian Schneider dies aged 73

Florian Schneider, co-founder of the pioneering electronic music group Kraftwerk, has died at the age of 73.




ed

Four-year-old with cancer reunited with father after seven weeks kept apart in lockdown

Mila Sneddon hasn't seen her father in seven weeks in order to keep her safe during coronavirus lockdown.




ed

Man arrested on suspicion of attempting to murder police officer

The officer’s injuries are not thought to be life-threatening.




ed

Medieval arrows caused similar injuries to gunshots, say archaeologists

Arrows fired from longbows could penetrate right through the human skull creating small entry and large exit wounds.




ed

People want to see green spaces prioritised after lockdown – poll

Survey finds people are appreciating their local parks, countryside and green belt more.




ed

Portrait of Dame Vera Lynn unveiled to mark VE Day

The oil on canvas painting is entitled The Enduring Sweetheart.




ed

Special front cover of The Big Issue created by Gruffalo illustrator

Characters created by Axel Scheffler from his popular books with Julia Donaldson are on the cover.




ed

Only half of businesses prepared to return to pre-crisis levels after lockdown lifts

One in twenty businesses said they would be unable to viably operate as long as social distances measures are still enforced.




ed

Woman charged with murder of church warden in Co-op attack

Zara Anne Radcliffe, 29, will appear in court accused of murdering 88-year-old John Rees and the attempted murder of three others.




ed

What is likely to change as lockdown measures are eased and what isn’t?

While the Government’s aim is to return things to normal as far as possible, it is likely that some measures will remain in place.




ed

Tesla chief Elon Musk set for £600m payday after targets reached

He will receive nearly 1.69 million stock options priced at 350.02 dollars (£285).




ed

Shipment of 400,000 delayed protective gowns from Turkey deemed unusable

A shipment of 400,000 gowns from Turkey which was part of a delayed consignment of PPE has been impounded after falling short of standards.




ed

What does the Virgin Media-O2 merger mean for the UK?

The two firms have announced plans to bring together their mobile, broadband and pay-TV services.




ed

We’ve passed the peak - but Boris Johnson should remember that most accidents happen on the way down

Lockdown restrictions are set to be eased - Tom Clarke shares his reservations on the idea.




ed

Nottingham MP claims she was 'sacked' as volunteer carer for speaking out on PPE

The care home where she worked says they no longer needed the help of the UK’s youngest parliamentarian.




ed

Nicola Sturgeon says lockdown must continue in Scotland but people may be allowed out more than once per day to exercise

Scotland's First Minister Nicola Sturgeon says the lockdown period in the country should be extended.




ed

Notting Hill Carnival 2020: Event cancelled for the first time ever

Notting Hill Carnival has been cancelled for the first time ever because of the ongoing coronavirus crisis.




ed

Lockdown: Any easing of coronavirus restrictions in England will be 'very limited', No 10 says

The government will move with "maximum caution" when lifting coronavirus lockdown restrictions in England, Number 10 has said.




ed

UK coronavirus death toll increases to 30,615 as further 539 deaths confirmed

Dominic Raab announced the latest figures during the daily briefing.




ed

Study begins into how coronavirus spreads and why some people are more affected than others

As part of the study, samples of blood, saliva and nasal swabs from healthcare workers in a bid to answer key questions about the virus.




ed

Is the UK ready for the coronavirus lockdown to be eased?

Number 10 said the government will move with "maximum caution" when lifting restrictions in England, but some are worried.




ed

Legal proceedings launched against Andrew ‘over unpaid ski resort bill’

Le Temps newspaper says the chalet was bought in 2014.




ed

Increase in driving blamed on ‘lockdown fatigue’

RAC data shows that drivers clocked up 23% more miles per day last week compared with four weeks earlier.




ed

Lower paid essential workers ‘substantially constrained’ over childcare

The report stated that the groups identified are not an exhaustive list of essential employees.




ed

Consumer confidence ‘severely depressed’ as families sit on their cash

A new survey by GfK found there was a slight overall improvement in mood but fears for the future remain.




ed

AI used to create ‘one-stop shop’ of coronavirus scientific research

It is hoped the development will accelerate the search for promising new drug targets and treatments.




ed

At-risk workers must have right to be furloughed, says charity

Citizens Advice claims cancer patients are among those having to go to work despite being eligible for the job retention scheme.




ed

VE Day remembered as 'day of hope' and lockdown exit plans lead the papers

The marking of Victory in Europe and the coronavirus lead the Friday papers.




ed

How Florence Nightingale shaped the way modern nurses are tackling coronavirus

Nightingale pioneered many of the practices carried out today, such as maintaining good hygiene and regularly washing hands




ed

Queen’s televised addresses just weeks apart

The monarch will speak to the nation on Friday to mark 75 years since VE Day.




ed

Father and son charged with murder in death of Ahmaud Arbery

The arrests followed the release of a video of the February incident which sparked national outcry.




ed

Public urged to resist going outdoors over bank holiday weekend

Resist the urge to sunbath and socialise despite hints from the PM lockdown might be eased soon, Dominic Raab said.




ed

Lockdown changes for Wales to be announced tomorrow

Welsh ministers understood to have agreed only 'cautious' changes to lockdown restrictions here in Wales




ed

Public warned to expect ‘limited' changes to lockdown in England

Culture Secretary Oliver Dowden said the government was also prepared to row back from easing restrictions if ‘things…get out of control’.




ed

Lockdown extended for three more weeks in Wales

Exercise will be permitted more than once a day but only if it begins and ends at home.




ed

UK Weather Forecast: Warm sunny spells and scattered showers today and tomorrow.

Warm sunny spells and scattered showers today and tomorrow.




ed

UK nations may move at different speeds on easing lockdown, Nicola Sturgeon says

The First Minister of Scotland said the lockdown would continue in Scotland.




ed

'No need to get worked up': Britons urged to abide by coronavirus lockdown rules ahead of Sunday's review

It comes as a six-week-old baby was among the 332 deaths announced by NHS England.