Biomater. Sci., 2020, 8,2234-2244
DOI: 10.1039/C9BM01931F, Paper

Qiaojie Luo, Xiaojun Li, Ying Wang, Jianfang He, Qiao Zhang, Pengfei Ge, Xia Cai, Qiang Sun, Weipu Zhu, Zhiquan Shen, Xiaodong Li
A biodegradable CO₂-based polymeric nanodrug is obtained via a surfactant- and solvent-free miniemulsion preparation, which can be concentrated at tumor site by EPR and releases the encapsulated drug through pH responsiveness.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2274-2282
DOI: 10.1039/C9BM02036E, Paper

Yue Cai, Zhuomin Xu, Qi Shuai, Fangtao Zhu, Jiao Xu, Xin Gao, Xuanrong Sun
PEG-PLA micelles are modified with F3 peptides, thus endowing the micelles with active-targeting ability due to the nucleolin-binding ability of the F3 peptides.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2283-2288
DOI: 10.1039/D0BM00088D, Paper

Guihong Lu, Liping Zuo, Jinfeng Zhang, Houshun Zhu, Wanru Zhuang, Wei Wei, Hai-Yan Xie
A highly efficient two-step targeting strategy integrating metabolic lipid-engineering with in situ click chemistry is developed, thus significantly improved the tumor theranostic performance of the red blood cells ghosts based drug delivery.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2245-2254
DOI: 10.1039/C9BM02010A, Paper

Gil Yeroslavsky, Masakazu Umezawa, Kyohei Okubo, Karina Nigoghossian, Doan Thi Kim Dung, Keiji Miyata, Masao Kamimura, Kohei Soga
Encapsulation of ICG and IR-1061 in PCL–PEG micelles producing agents with increased stability of ICG and tunable PTT and PDT activity. The micelles are also useful for NIR imaging and NIR nanothermometry.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2120-2128
DOI: 10.1039/D0BM00242A, Paper

Yan Fang Cheng, Dicky Pranantyo, Gopinath Kasi, Zhi Song Lu, Chang Ming Li, Li Qun Xu
An amino-containing tannic acid derivative was self-polymerized to form colorless and uniform coatings on various substrate surfaces, and the resultant coatings can be further utilized to construct bioactive, antifouling and antibacterial surfaces.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00453G, Paper

Zhongzheng Yu, Yong Yao Chun, Jingwen Xue, Jodie Zu Yi Tan, Wen Kiat Chan, Weizheng Cai, Yan Zhang, Timothy Thatt Yang Tan
Balancing the thickness of sensitizing and inert layers in neodymium-sensitized tetralayer nanoconstructs for optimal ultraviolet upconversion.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00323A, Paper

Bunty Sharma, Gurpreet Kaur, Ganga Ram Chaudhary, Santosh L. Gawali, P. A. Hassan
Developments in the field of photodynamic therapy (PDT) are being made by investigating appropriate photosensitizers (PSs) and enhancing the penetration effect of light by developing new metallocatanionic vesicles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02056J, Paper

Yadu N. Vakkipurath Kodakkadan, Kristyna Idzakovicova, Josef Sepitka, Daniël ten Napel, Eric Safai, Petr Cigler, Frantisek Štěpánek, Ivan Rehor
We introduce a method for photolithographic synthesis of arbitrarily shaped microgels composed purely of a biopolymer of choice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00187B, Paper

Yuping Hu, Xuechun Wang, Peng Zhao, Hao Wang, Wei Gu, Ling Ye
The accelerated O₂ release from CaO₂ catalyzed by MnO₂ nanozyme leads to a rapid and efficient hypoxia relief, an increased yield of ¹O₂, a down-regulated HIF-1α and VEGF, and eventually a super-efficient PDT.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00015A, Paper

Manisha Ahir, Priyanka Upadhyay, Avijit Ghosh, Sushmita Sarker, Saurav Bhattacharya, Payal Gupta, Swatilekha Ghosh, Sreya Chattopadhyay, Arghya Adhikary
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00331J, Communication

Yihang Wu, Yue Xiong, Ling Wang, Quanming Zhou, Linxian Li, Pavel A. Levkin, Gary Davidson, Liqian Gao, Wenbin Deng
A library of lipidoids self-assembling to liposomes exhibits excellent transfection efficiency in HEK 293T cells and mESCs with low cytotoxicity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM90037K, Correction

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Zhilin Liu, Na Shen, Zhaohui Tang, Dawei Zhang, Lili Ma, Chenguang Yang, Xuesi Chen
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01990A, Paper

Taufiq Ahmad, Hayeon Byun, Hyeok Jun Shin, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Young Min Shin, Heungsoo Shin
Adenosine and its receptors have emerged as alternative targets to control cellular functions for bone healing.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00155D, Paper

Sergio Acosta, Arturo Ibañez-Fonseca, Conrado Aparicio, J. Carlos Rodríguez-Cabello
Protein-engineered polymers can be used as multivalent platforms for AMP tethering on implant surfaces as cytocompatible coatings with strong antibiofilm properties.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00063A, Paper

Yuyang Xia, Hongying Bao, Jie Huang, Xiaodi Li, Chenggong Yu, Zhijun Zhang, Haishui Wang
A dual-labeling strategy integrating near-infrared-persistent luminescence and RfLuc-based bioluminescence imaging techniques has been developed to track the transplanted stem cells, deepening the understanding of the role played by stem cells in PF treatment.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00076K, Paper

Jungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung Lee
Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00003E, Paper

Jia Qu, Dengke Teng, Guoqing Sui, Shihui Guan, Yang Wang, Qimeihui Wang, Yuanqiang Lin, Haitao Ran, Zhigang Wang, Hui Wang
The advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00159G, Minireview

Nicole F. Steinmetz, Sierin Lim, Frank Sainsbury
Protein cages found in nature have evolved for a variety of purposes and this review focuses on how they are being co-opted for use in immunotherapy and therapeutic delivery.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01968E, Paper

Teng Zhang, Qingguang Wei, Hua Zhou, Wenhao Zhou, Daoyang Fan, Xinhong Lin, Zehao Jing, Hong Cai, Yan Cheng, Xiaoguang Liu, Weishi Li, Chunli Song, Yun Tian, Nanfang Xu, Yufeng Zheng, Zhongjun Liu
Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6A14V for treating MRSA bone infection and enhancing osteogenesis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00062K, Paper

Chaoli Xu, Ting Zhang, Guangming Lu, Kun Chen, Jun Tao, Yunlei Zhang, Zhaogang Teng, Bin Yang
Herein, we successfully constructed a combined therapeutic nanoplatform with high tumor targeting for cancer treatment by integrating gold nanorods with disulfiram (denoted Au-DSF). The Au-DSF integrates possess a uniform length...
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2447-2458
DOI: 10.1039/C9BM01889A, Paper

Yanqiu Wang, Xinyu Shen, Shang Ma, Qianqian Guo, Wei Zhang, Lu Cheng, Liming Ding, Zhuobin Xu, Jing Jiang, Lizeng Gao
Combining nanozymes and bacteria to eliminate dental biofilms in a mixed-species model.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2481-2487
DOI: 10.1039/D0BM00021C, Paper

Zhen Ke, Aize Xie, Jianjiao Chen, Zhenyuan Zou, Lei Shen, Yansong Dai, Dengfeng Zou
Hypericin undergoing electron transfer can be used for type I PDT and PTT.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper

Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2472-2480
DOI: 10.1039/D0BM00172D, Paper

Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper

Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2590-2599
DOI: 10.1039/D0BM00314J, Paper

Julie Tzu-Wen Wang, Umberto Martino, Rehan Khan, Maasoomeh Bazzar, Paul Southern, Dönüş Tuncel, Khuloud T. Al-Jamal
Self-red-emitting magnetic PLGA-PEG nanocapsules for optical imaging and magnetic tumour targeting.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2366-2375
DOI: 10.1039/C9BM02098E, Review Article

Jie Wu, Guanghui Ma
The design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2507-2513
DOI: 10.1039/D0BM00078G, Paper

Rong Jin, Jing Sun, Liefu Zhou, Xuelian Guo, Aoneng Cao
Core-crosslinked dual-responsive micelles can be readily constructed from a pair of clickable copolymers and applied for controlled release of anticancer drugs in cancer therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2488-2506
DOI: 10.1039/C9BM02081K, Paper

Hai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao Ran
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper

Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)₂ complex as a promising hypoxia selective cytotoxin in prostate cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2627-2637
DOI: 10.1039/D0BM00041H, Paper

Hwan D. Kim, Jungha Park, Sivashanmugam Amirthalingam, R. Jayakumar, Nathaniel S. Hwang
VEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2537-2548
DOI: 10.1039/D0BM00104J, Paper

Weinan Cheng, Zhaozhao Ding, Xin Zheng, Qiang Lu, Xiangdong Kong, Xiaozhong Zhou, Guozhong Lu, David L. Kaplan
Tunable multiple angiogenic and osteogenic cues were introduced into hydrogel systems simultaneously to optimize the niches for bone regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2666-2672
DOI: 10.1039/C9BM02063B, Paper

Xiao-Ting Gong, Wenguang Xie, Jing-Jing Cao, Shengxiang Zhang, Kanyi Pu, Hao-Li Zhang
A NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2376-2393
DOI: 10.1039/D0BM00129E, Review Article

Lifen Huang, Jun Huang, Junbin Huang, Hongman Xue, Zhiqing Liang, Jun Wu, Chun Chen
Nanoparticles (NPs) are used for the diagnosis and treatment of hematological tumors by loading various pharmacodynamic molecules.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, 8,2398-2403
DOI: 10.1039/C9BM01757G, Communication

Ewa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank Caruso
Multilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00311E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong Park
The use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper

Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,842-849
DOI: 10.1039/C9TX00069K, Paper

M. Martinez, I. M. U. Rossetto, R. M. S. Arantes, F. S. N. Lizarte, L. F. Tirapelli, D. P. C. Tirapelli, L. G. A. Chuffa, F. E. Martinez
Alcoholism is a multifactorial disease with high risk for dependence determined by genetic background, environmental factors and neuroadaptations.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,850-861
DOI: 10.1039/C9TX00067D, Paper

Wei Huang, Chuanxin Liu, Lijuan Xie, Yuming Wang, Yanyan Xu, Yubo Li
Integrated network pharmacology and targeted metabolomics to reveal the nephrotoxicity mechanism of triptolide.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,875-884
DOI: 10.1039/C9TX00100J, Paper

Xuan-Ying Chen, Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping Xiong
Bevacizumab (BVZ) is a widely investigated angiogenesis inhibitor in cancer patients. Although the anti-tumor effects has been verified, cardiotoxicity may be the most serious side-effect for BVZ.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,908-917
DOI: 10.1039/C9TX00146H, Paper

Yiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
Cadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,928-938
DOI: 10.1039/C9TX00191C, Paper

Xuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper

Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,953-963
DOI: 10.1039/C9TX00147F, Paper

Fatemeh Amereh, Akbar Eslami, Simin Fazelipour, Mohammad Rafiee, Mohammad Ismail Zibaii, Mohammad Babaei
At this time, little is known about the long-term effects of micro(nano)plastics on public health. In the present study, early warning signs of thyroid endocrine disruption were noticed in adult Wistar rats from the ingestion of virgin polystyrene nanoparticles.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,994-1001
DOI: 10.1039/C9TX00126C, Paper

Yan-Ming Xu, Heng Wee Tan, Wei Zheng, Zhan-Ling Liang, Fei-Yuan Yu, Dan-Dan Wu, Yue Yao, Qiu-Hua Zhong, Rui Yan, Andy T. Y. Lau
A comparative proteome analysis was conducted to identify global changes in the protein expression profiles of cadmium telluride quantum dot-exposed human bronchial epithelial BEAS-2B cells.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,988-993
DOI: 10.1039/C9TX00193J, Paper

Ali Raza Ebrahim Soltani, Abdolmohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad Sistani
Inhalatory anesthetics may impact spermatogenesis and sexual behavior.
The content of this RSS Feed (c) The Royal Society of Chemistry

Toxicol. Res., 2019, 8,972-978
DOI: 10.1039/C9TX00142E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Rashin Ghaffari, John H. Richburg
Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
The content of this RSS Feed (c) The Royal Society of Chemistry