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Multifunctional streptavidin–biotin conjugates with precise stoichiometries

Chem. Sci., 2020, 11,4422-4429
DOI: 10.1039/D0SC01589J, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Dongdong Xu, Seraphine V. Wegner
Multifunctional streptavidin-biotin conjugates with defined stoichiometry and number of open binding pockets provide molecularly precise alternatives to the statistical mixture of products that typically forms.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A highly stable RNA aptamer probe for the retinoblastoma protein in live cells

Chem. Sci., 2020, 11,4467-4474
DOI: 10.1039/D0SC01613F, Edge Article
Open Access
Thao T. Le, Andreas Bruckbauer, Bogachan Tahirbegi, Alastair J. Magness, Liming Ying, Andrew D. Ellington, Anthony E. G. Cass
An RNA G-quadruplex aptamer, specific for the human retinoblastoma protein (RB) and highly stable inside cells, is selected and its application to live cell probing of the protein illustrated.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Geometric landscapes for material discovery within energy–structure–function maps

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC00049C, Edge Article
Open Access
Seyed Mohamad Moosavi, Henglu Xu, Linjiang Chen, Andrew I. Cooper, Berend Smit
We introduce a representation for the geometric features of the pores of porous molecular crystals. This representation provides a good basis for supervised (predict adsorption properties) and unsupervised (polymorph classification) tasks.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Quinone Methide Dimers Lacking Labile Hydrogen Atoms Are Surprisingly Excellent Radical-Trapping Antioxidants

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC02020F, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Derek A. Pratt, Mark A R Raycroft, Jean-Philippe R Chauvin, Matthew Galliher, Kevin Romero, Corey Stephenson
Hydrogen atom transfer (HAT) is the mechanism by which the vast majority of radical-trapping antioxidants (RTAs), such as hindered phenols, inhibit autoxidation. As such, at least one weak O–H bond...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Regioselective Molybdenum-catalyzed allylic substitution of tertiary allylic electrophiles: methodology development and applications

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC01763A, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Muhammad Salman, Yaoyao Xu, Shahid Khan, Junjie Zhang, Ajmal Khan
The first molybdenum-catalyzed allylic sulfonylation of tertiary allylic electrophile is described. The method utilizes a readily accesable catalyst (Mo(CO)6/2,2'-bipyridine, both are commercially available) and represent the first example of the...
The content of this RSS Feed (c) The Royal Society of Chemistry




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N2Phos – an easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki–Miyaura cross couplings in water

Chem. Sci., 2020, Advance Article
DOI: 10.1039/D0SC00968G, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nnamdi Akporji, Ruchita R. Thakore, Margery Cortes-Clerget, Joel Andersen, Evan Landstrom, Donald H. Aue, Fabrice Gallou, Bruce H. Lipshutz
A new, biaryl phosphine-containing ligand, N2Phos, forms a 1 : 1 complex with Pd resulting in an active catalyst at the ppm level for Suzuki–Miyaura couplings in water, enabled by an aqueous micellar medium. Notably, aryl chlorides are shown to be amenable substrates.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Electrochemical Radical Reactions of Alkyl Iodides: A Highly Efficient, Clean, Green Alternative to Tin Reagents

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC01694B, Edge Article
Open Access
diyuan Li, Tsz-Kan Ma, Reuben J Scott, Jonathan David Wilden
An electrochemical ‘redox-relay’ system has been developed which allows the generation of C-centered radicals. Intermolecular ‘tin-like’ radical reactions can subsequently be conducted under the most benign of conditions. The yields...
The content of this RSS Feed (c) The Royal Society of Chemistry




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'Procure TrueNat machines for speedy corona test'

CM Nitish Kumar on Thursday ordered expeditious procurement of TrueNat machines and their installation in all district hospitals for speedy coronavirus test results. The machine yields the result in less than an hour if it is negative, and in the case of positive case, it requires cross-checking with the other method.




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Delhi: 2nd 'shramik spl train' leaves for Bihar

The workers were ferried to the New Delhi Railway station mostly in Delhi Transport Corporation (DTC) buses, and in some cases in police vans from shelters homes run by the city government.




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We are buying in this market on a daily basis, says LIC MD Vipin Anand

The IPO is a time-consuming thing, which is going to be there, says Vipin Anand.




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Japan IPO cancellations hit record this month on coronavirus

Investors who had planned to buy new offerings might opt for existing start-up shares instead.




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Half of FY20 IPOs hold head above water in this selloff, some remain multibaggers

Out of the 15 stocks that got listed in FY 2019-20, seven are still trading above issue prices.




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Preschool in three cultures revisited : China, Japan, and the United States / Joseph Tobin, Yeh Hsueh, and Mayumi Karasawa

Tobin, Joseph Jay




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International guide to student achievement / edited by John Hattie, Eric M. Anderman




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Reflective teaching in higher education / Paul Ashwin and [and 10 others]

Ashwin, Paul, 1970-




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Researching higher education : international perspectives on theory, policy and practice / edited by Jennifer M. Case and Jeroen Huisman




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Teaching and learning for the twenty-first century : educational goals, policies, and curricula from six nations / Fernando M. Reimers, Connie K. Chung, editors




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Handbook of research on teaching / edited by Drew H. Gitomer and Courtney A. Bell




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Observation [videorecording] : the developing child / Magna Systems, Inc. ; program producers, Shanta and Milan Herzog ; design and script, Janet Gonzalez-Mena ; editor, Susan Jenkins




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The inside story [videorecording] : developing children's understanding about their bodies




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Corporate humanities in higher education : moving beyond the neoliberal academy / Jeffrey R. Di Leo

Di Leo, Jeffrey R., author




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Neoliberalism, education, and terrorism : contemporary dialogues / by Jeffrey R. Di Leo, Henry A. Giroux, Sophia McClennen, and Kenneth J. Saltman

Di Leo, Jeffrey R., author




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Thinking with a line (TWAL©) : teacher's guide to the interactive CD-ROM / Cathy Weisman Topal

Topal, Cathy Weisman, author




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Thinking through new literacies for primary and early years / Jayne Metcalfe [and three others] ; edited by Dr Eileen Honan

Metcalfe, Jayne, author




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Situation models and children's reading comprehension : what role does visual imagery play? / by Maroulia Katsipis

Katsipis, Maroulia, author




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Teaching for social justice : a Democracy and education reader / edited by William Ayers, Jean Ann Hunt, and Therese Quinn




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Loose parts : inspiring play in young children / Lisa Daly and Miriam Beloglovsky ; photography by Jenna Daly

Daly, Lisa




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Teaching language in context / Beverly Derewianka, Pauline Jones

Derewianka, Beverly, 1946- author




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Early childhood and neuroscience : theory, research and implications for practice / Mine Conkbayir

Conkbayir, Mine, author




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Still learning to think thinking to learn : within the Australian curriculum : planning with a thinking focus / Michael Pohl

Pohl, Michael, author




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Teaching thinking skills in the primary years : a whole school approach / by Michael Pohl

Pohl, Michael




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Effective teaching strategies : lessons from research and practice / Roy Killen

Killen, Roy, 1947-




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Learning English as a second language in the early years : hundreds of ideas for supporting children with English as an additional language / Anita Soni & Liz Rouse

Soni, Anita, (Educational psychologist), author




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Making learning whole : how seven principles of teaching can transform education / David N. Perkins

Perkins, David N




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How colleges work : the cybernetics of academic organization and leadership / Robert Birnbaum

Birnbaum, Robert




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Savage inequalities : children in America's schools / Jonathan Kozol

Kozol, Jonathan, author




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You're telling the story : how to develop useful assessments for learning in early childhood / Janet Moles

Moles, Janet




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A study on the effectiveness of anonymous agents in computer-supported collaborative learning (CSCL) for the facilitation of student learning and execution of team projects / Wudhijaya Philuek

Philuek, Wudhijaya, author




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Record of oral language : observing changes in the acquisition of language structures : a guide for teaching / Marie M. Clay, Malcolm Gill, Ted Glynn, Tony McNaughton, Keith Salmon

Clay, Marie M. (Marie Mildred), author




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Handbook of research on collaborative teaching practice in virtual learning environments / Gianni Panconesi (Esplica, Italy), Maria Guida (National Institute for Documentation, Innovation, and Educational Research, Italy), [editors]




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Numeracy and learning difficulties : approaches to teaching and assessment / Peter Westwood

Westwood, Peter S. (Peter Stuart), 1936- author




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Teaching the arts : early childhood and primary education / David Roy, William Baker, Amy Hamilton

Roy, David M. S., author




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Comparative and international education : an introduction to theory, method, and practice / David Phillips and Michele Schweisfurth

Phillips, David, 1944 December 15- author




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Teaching in inclusive school environments / Roselyn Dixon, Stuart Woodcock, Kathleen Tanner, Leanne Woodley, Amanda Webster

Dixon, Roselyn M




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50 fantastic ideas for exploring emotions / Sally and Phill Featherstone

Featherstone, Sally, author




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The toxic university : zombie leadership, academic rock stars and neoliberal ideology / John Smyth

Smyth, W. J. (William John), 1944- author




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Developing the curriculum : improved outcomes through systems approaches / William R. Gordon II, Ed.D. (Chief Operations Officer, Retired, Florida virtual School, Orlando, Florida), Rosemarye T. Taylor, Ph.D. (Professor, Educational Leadership, University

Gordon, William, II, author




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Assessment for teaching / edited by Patrick Griffin




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The early years of schooling. Defining and clarifying intentional teaching, guided play and child-directed play and learning / Western Australian Primary Principals' Association




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Media and moral education : a philosophy of critical engagement / Laura D'Olimpio

D'Olimpio, Laura, author