la The regulation and functions of DNA and RNA G-quadruplexes By feeds.nature.com Published On :: 2020-04-20 Full Article
la The expanding regulatory mechanisms and cellular functions of circular RNAs By feeds.nature.com Published On :: 2020-05-04 Full Article
la Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal By feeds.nature.com Published On :: 2020-04-23 Full Article
la Defense Playbook for Campaigns By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020The 2018 National Defense Strategy (NDS) is predicated on a single organizing principle: America’s military pre-eminence is rapidly eroding. This is not a new concept. For years, experts have warned that the economic and technological advancements of U.S. adversaries, coupled with the 2008 financial crisis and America’s focus on peripheral conflicts, have caused a decline in America’s military dominance. In this context, the advances of near-peer competitors such as China and Russia have created plausible “theories of victory” in potential conflicts across Eastern Europe and East Asia. Competitors’ unaddressed improvements in strategic innovation, economic investment, and dual-use technology increases the risk of conflict and strains the U.S. alliance system. It is urgent that the United States reestablish and maintain credible deterrents against these near-peer competitors. After decades of focusing on post-Cold War ‘shaping’ operations, the American military needs to reinvigorate for full spectrum great power competition. This report is intended as a blueprint on how to begin that process from graduate students at the Belfer Center for Science and International Affairs at Harvard University. Contained inside are 12 memorandums. Each provides a high-level overview and specific recommendations on a key issue of American defense policy. Full Article
la Oil's Collapse Is a Geopolitical Reset In Disguise By feedproxy.google.com Published On :: Apr 29, 2020 Apr 29, 2020The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets. Full Article
la Breaking the Ice: How France and the UK Could Reshape a Credible European Defense and Renew the Transatlantic Partnership By feedproxy.google.com Published On :: May 7, 2020 May 7, 2020History is replete with irony, but rarely more poignantly than in the summer of 2016 when, on 23 June, the UK voted to leave the European Union and the next day, 24 June, the EU published its Global Strategy document asserting its ambition of “strategic autonomy.” Whither Franco-British defense cooperation in such chaotic circumstances? This paper attempts to provide the outline of an answer to that question. Full Article
la Defense Playbook for Campaigns By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020The 2018 National Defense Strategy (NDS) is predicated on a single organizing principle: America’s military pre-eminence is rapidly eroding. This is not a new concept. For years, experts have warned that the economic and technological advancements of U.S. adversaries, coupled with the 2008 financial crisis and America’s focus on peripheral conflicts, have caused a decline in America’s military dominance. In this context, the advances of near-peer competitors such as China and Russia have created plausible “theories of victory” in potential conflicts across Eastern Europe and East Asia. Competitors’ unaddressed improvements in strategic innovation, economic investment, and dual-use technology increases the risk of conflict and strains the U.S. alliance system. It is urgent that the United States reestablish and maintain credible deterrents against these near-peer competitors. After decades of focusing on post-Cold War ‘shaping’ operations, the American military needs to reinvigorate for full spectrum great power competition. This report is intended as a blueprint on how to begin that process from graduate students at the Belfer Center for Science and International Affairs at Harvard University. Contained inside are 12 memorandums. Each provides a high-level overview and specific recommendations on a key issue of American defense policy. Full Article
la Oil's Collapse Is a Geopolitical Reset In Disguise By feedproxy.google.com Published On :: Apr 29, 2020 Apr 29, 2020The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets. Full Article
la Breaking the Ice: How France and the UK Could Reshape a Credible European Defense and Renew the Transatlantic Partnership By feedproxy.google.com Published On :: May 7, 2020 May 7, 2020History is replete with irony, but rarely more poignantly than in the summer of 2016 when, on 23 June, the UK voted to leave the European Union and the next day, 24 June, the EU published its Global Strategy document asserting its ambition of “strategic autonomy.” Whither Franco-British defense cooperation in such chaotic circumstances? This paper attempts to provide the outline of an answer to that question. Full Article
la Spying: Hiding in Plain Sight By feedproxy.google.com Published On :: Mar 11, 2020 Mar 11, 2020Spycraft has always excited people, with stories of daring agents using high-tech wizardry to bust terrorists in the act. But the reality is much less glamorous—and much more dangerous. As spying entered the 1960s, technology started to play a serious role in getting intel. Full Article
la In Memoriam: Patricia McLaughlin By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020Patricia (Pat) McLaughlin, our beloved colleague and friend at the Center since 2001, passed away in February after a brief illness. Hired as Faculty Assistant to John Holdren, Co-Director of the Center’s Science, Technology, and Public Policy Program (STPP) nearly 20 years ago, she continued to work with STPP and with John until her illness. Full Article
la Closing Critical Gaps that Hinder Homeland Security Technology Innovation By feedproxy.google.com Published On :: Apr 23, 2020 Apr 23, 2020Rapid technological advances are making nonstate actors much more capable than they were even a decade ago. Malicious actors like terrorist groups, criminal organizations, and state proxies are increasingly able to threaten American civilians and their interests around the world. At the same time, we are increasingly vulnerable to the emergence of new disease and natural disasters, as vividly shown by the hurricanes of 2017 (Harvey, Irma, and Maria) and the COVID-19 pandemic. Effectively countering these threats, including by developing and supporting private sector-generated new technological solutions, is a core government responsibility. DHS is the U.S. government’s primary civilian public safety agency and the main source of government funding for nonmilitary development of public safety technologies. Unfortunately, DHS has a poor record of developing new technological solutions to advance its mission and address emerging threats. This article assesses the current situation, identifies lines of research that are urgently needed, and makes recommendations on how DHS can more effectively partner with industry and how new technologies can be quickly seeded. Full Article
la Spying: Hiding in Plain Sight By feedproxy.google.com Published On :: Mar 11, 2020 Mar 11, 2020Spycraft has always excited people, with stories of daring agents using high-tech wizardry to bust terrorists in the act. But the reality is much less glamorous—and much more dangerous. As spying entered the 1960s, technology started to play a serious role in getting intel. Full Article
la In Memoriam: Patricia McLaughlin By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020Patricia (Pat) McLaughlin, our beloved colleague and friend at the Center since 2001, passed away in February after a brief illness. Hired as Faculty Assistant to John Holdren, Co-Director of the Center’s Science, Technology, and Public Policy Program (STPP) nearly 20 years ago, she continued to work with STPP and with John until her illness. Full Article
la Closing Critical Gaps that Hinder Homeland Security Technology Innovation By feedproxy.google.com Published On :: Apr 23, 2020 Apr 23, 2020Rapid technological advances are making nonstate actors much more capable than they were even a decade ago. Malicious actors like terrorist groups, criminal organizations, and state proxies are increasingly able to threaten American civilians and their interests around the world. At the same time, we are increasingly vulnerable to the emergence of new disease and natural disasters, as vividly shown by the hurricanes of 2017 (Harvey, Irma, and Maria) and the COVID-19 pandemic. Effectively countering these threats, including by developing and supporting private sector-generated new technological solutions, is a core government responsibility. DHS is the U.S. government’s primary civilian public safety agency and the main source of government funding for nonmilitary development of public safety technologies. Unfortunately, DHS has a poor record of developing new technological solutions to advance its mission and address emerging threats. This article assesses the current situation, identifies lines of research that are urgently needed, and makes recommendations on how DHS can more effectively partner with industry and how new technologies can be quickly seeded. Full Article
la Innovations in dialysis membranes for improved kidney replacement therapy By feeds.nature.com Published On :: 2020-04-22 Full Article
la Targeting inflammation in AKI by P2Y14 receptor inhibition in mice By feeds.nature.com Published On :: 2020-05-05 Full Article
la Lebanon has formed a controversial new government in a polarised, charged atmosphere, and protesters are not going to be easily pacified by its promises, explains Rami Khoury. By feedproxy.google.com Published On :: Jan 22, 2020 Jan 22, 2020The fourth consecutive month of Lebanon's unprecedented political and economic crisis kicked off this week with three dramatic developments that will interplay in the coming months to define the country's direction for years to come: Escalating protests on the streets, heightened security measures by an increasingly militarising state, and now, a new cabinet of controversial so-called "independent technocrats" led by Prime Minister-designate Hassan Diab. Seeking to increase pressure on the political elite to act responsibly amid inaction vis-a-vis the slow collapse of the economy, the protesters had launched the fourth month of their protest movement, which had begun on 17 October last year, with a 'Week of Anger', stepping up their tactics and targeting banks and government institutions. Full Article
la H-Diplo Review Essay 192 on Lawson. Anatomies of Revolution By feedproxy.google.com Published On :: Feb 14, 2020 Feb 14, 2020Emily Whalen reviews Anatomies of Revolution by George Lawson (Cambridge: Cambridge University Press, 2019). Full Article
la The Future of the Transatlantic Defense Relationship: Views from Finland and the EU By feedproxy.google.com Published On :: Mar 3, 2020 Mar 3, 2020February 7, 2020: With the advent of the digital age and the rise of Russia and China as global powers, the EU must do more to defend itself and its relationship with the United States, according to Janne Kuusela, Director General Janne Kuusela. In an event moderated by Cathryn Clüver Ashbrook, Executive Director of the Future of Diplomacy Project and the Project on Europe and the Transatlantic Relationship he explained why Finland could be a potential paradigm for the EU’s defense strategy. Full Article
la A β-galactosidase kiss of death for senescent cells By feeds.nature.com Published On :: 2020-05-04 Full Article
la Molecular architecture of the luminal ring of the <i>Xenopus laevis</i> nuclear pore complex By feeds.nature.com Published On :: 2020-05-04 Full Article
la Structure of the cytoplasmic ring of the <i>Xenopus laevis</i> nuclear pore complex by cryo-electron microscopy single particle analysis By feeds.nature.com Published On :: 2020-05-06 Full Article
la Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity By feeds.nature.com Published On :: 2020-05-06 Full Article
la Urban Waste to Energy Recovery Assessment Simulations for Developing Countries By feedproxy.google.com Published On :: Mar 26, 2020 Mar 26, 2020In this paper, a quantitative Waste to Energy Recovery Assessment (WERA) framework is used to stochastically analyze the feasibility of waste-to-energy systems in selected cities in Asia. Full Article
la Transatlantic Dialogue: The Missing Link in Europe’s Post-Covid-19 Green Deal? By feedproxy.google.com Published On :: Apr 10, 2020 Apr 10, 2020This policy brief emphasizes that the European Green Deal's effectiveness in a post Covid-19 world will require the involvement of strategic partners, especially the US. In the context of a potential US withdrawal from the Paris Agreement and the consequential vacuum, it will be even more important to engage the US in implementing the GD. In light of divergence between the US and the EU during past climate negotiations (e.g. Kyoto, Copenhagen, and Paris), we suggest a gradual approach to US engagement with GD initiatives and objectives. Full Article
la Oil's Collapse Is a Geopolitical Reset In Disguise By feedproxy.google.com Published On :: Apr 29, 2020 Apr 29, 2020The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets. Full Article
la Can respirator face masks in a developing country reduce exposure to ambient particulate matter? By feeds.nature.com Published On :: 2020-04-21 Full Article
la Association between maternal exposure to particulate matter (PM<sub>2.5</sub>) and adverse pregnancy outcomes in Lima, Peru By feeds.nature.com Published On :: 2020-04-30 Full Article
la How neuroscience labs can limit their environmental impact By feeds.nature.com Published On :: 2020-05-08 Full Article
la The U.S. Is Now Resorting to Plan C By feedproxy.google.com Published On :: Apr 29, 2020 Apr 29, 2020Americans are not going to wait for sufficient testing. So what happens then? Juliette Kayyem describes "opening up" as a high-stakes version of a coloring book. States can use more and more crayons, but the goal is to avoid going over the edges. Full Article
la UK plans 14-day compulsory quarantine for all airport arrivals By economictimes.indiatimes.com Published On :: 2020-05-09T17:06:23+05:30 The UK is planning to bring in compulsory 14-day quarantine for all travellers arriving in the country from any part of the world, except the Republic of Ireland, as part of measures to track the spread of coronavirus. Full Article
la Over 1 lakh migrants to return to UP on 114 trains by Saturday night: Official By economictimes.indiatimes.com Published On :: 2020-05-09T18:10:47+05:30 Over 1 lakh migrant workers from Uttar Pradesh stranded in different parts of the country following the coronavirus-induced lockdown will return to the state by Saturday night on 114 trains, a senior government official said. Full Article
la JD(U) trashes Delhi govt's claim of bearing migrant labourers train fare By economictimes.indiatimes.com Published On :: 2020-05-09T18:46:35+05:30 The ruling JD(U) on Saturday slammed AAP for claiming that it bore the cost of ferrying migrant workers from Delhi to their home in Bihar, saying the party was speaking "half-truth" as the Arvind Kejriwal government has sought reimbursement of the payment. Full Article
la 1.5 lakh migrant workers want to return to Haryana, 8 lakh want to leave: Home Minister By economictimes.indiatimes.com Published On :: 2020-05-09T20:01:48+05:30 While nearly eight lakh migrant workers stranded in Haryana have registered themselves on a government portal to return to their native states, over 1.5 lakh of them have applied on the same portal from different states to return back to work, state Home Minister Anil Vij said. Full Article
la Spying: Hiding in Plain Sight By feedproxy.google.com Published On :: Mar 11, 2020 Mar 11, 2020Spycraft has always excited people, with stories of daring agents using high-tech wizardry to bust terrorists in the act. But the reality is much less glamorous—and much more dangerous. As spying entered the 1960s, technology started to play a serious role in getting intel. Full Article
la In Memoriam: Patricia McLaughlin By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020Patricia (Pat) McLaughlin, our beloved colleague and friend at the Center since 2001, passed away in February after a brief illness. Hired as Faculty Assistant to John Holdren, Co-Director of the Center’s Science, Technology, and Public Policy Program (STPP) nearly 20 years ago, she continued to work with STPP and with John until her illness. Full Article
la Closing Critical Gaps that Hinder Homeland Security Technology Innovation By feedproxy.google.com Published On :: Apr 23, 2020 Apr 23, 2020Rapid technological advances are making nonstate actors much more capable than they were even a decade ago. Malicious actors like terrorist groups, criminal organizations, and state proxies are increasingly able to threaten American civilians and their interests around the world. At the same time, we are increasingly vulnerable to the emergence of new disease and natural disasters, as vividly shown by the hurricanes of 2017 (Harvey, Irma, and Maria) and the COVID-19 pandemic. Effectively countering these threats, including by developing and supporting private sector-generated new technological solutions, is a core government responsibility. DHS is the U.S. government’s primary civilian public safety agency and the main source of government funding for nonmilitary development of public safety technologies. Unfortunately, DHS has a poor record of developing new technological solutions to advance its mission and address emerging threats. This article assesses the current situation, identifies lines of research that are urgently needed, and makes recommendations on how DHS can more effectively partner with industry and how new technologies can be quickly seeded. Full Article
la Defense Playbook for Campaigns By feedproxy.google.com Published On :: Mar 24, 2020 Mar 24, 2020The 2018 National Defense Strategy (NDS) is predicated on a single organizing principle: America’s military pre-eminence is rapidly eroding. This is not a new concept. For years, experts have warned that the economic and technological advancements of U.S. adversaries, coupled with the 2008 financial crisis and America’s focus on peripheral conflicts, have caused a decline in America’s military dominance. In this context, the advances of near-peer competitors such as China and Russia have created plausible “theories of victory” in potential conflicts across Eastern Europe and East Asia. Competitors’ unaddressed improvements in strategic innovation, economic investment, and dual-use technology increases the risk of conflict and strains the U.S. alliance system. It is urgent that the United States reestablish and maintain credible deterrents against these near-peer competitors. After decades of focusing on post-Cold War ‘shaping’ operations, the American military needs to reinvigorate for full spectrum great power competition. This report is intended as a blueprint on how to begin that process from graduate students at the Belfer Center for Science and International Affairs at Harvard University. Contained inside are 12 memorandums. Each provides a high-level overview and specific recommendations on a key issue of American defense policy. Full Article
la Oil's Collapse Is a Geopolitical Reset In Disguise By feedproxy.google.com Published On :: Apr 29, 2020 Apr 29, 2020The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets. Full Article
la Breaking the Ice: How France and the UK Could Reshape a Credible European Defense and Renew the Transatlantic Partnership By feedproxy.google.com Published On :: May 7, 2020 May 7, 2020History is replete with irony, but rarely more poignantly than in the summer of 2016 when, on 23 June, the UK voted to leave the European Union and the next day, 24 June, the EU published its Global Strategy document asserting its ambition of “strategic autonomy.” Whither Franco-British defense cooperation in such chaotic circumstances? This paper attempts to provide the outline of an answer to that question. Full Article
la H-Diplo Review Essay 192 on Lawson. Anatomies of Revolution By feedproxy.google.com Published On :: Feb 14, 2020 Feb 14, 2020Emily Whalen reviews Anatomies of Revolution by George Lawson (Cambridge: Cambridge University Press, 2019). Full Article
la Punjab govt advances paddy sowing, transplantation dates By economictimes.indiatimes.com Published On :: 2020-05-09T19:35:08+05:30 The agriculture department had earlier fixed May 10 as the date to begin sowing of paddy nursery and June 20 for paddy transplantation, during the current kharif season. The farmers had raised concerns about meeting the cultivation/sowing requirements in view of the labour shortage resulting from migrant labourers returning to their homes in view of the COVID-19 crisis. Full Article
la Extinction Watch: How African Black Rhino came back from extinction By economictimes.indiatimes.com Published On :: 2020-04-13T23:51:05+05:30 Between 2012 and 2018, the Black Rhino (Diceros bicornis) population across Africa has grown at a modest annual rate of 2.5% from an estimated 4,845 to 5,630 animals in the wild, respectively. Population models predict a further slow increase over the next five years, according to IUCN’s March 2020 update. Full Article