co An Overheated Narrative Unanswered: How the Global Compact for Migration Became Controversial By www.migrationpolicy.org Published On :: Fri, 14 Dec 2018 10:33:54 -0500 While the Global Compact for Safe, Orderly, and Regular Migration was formally adopted by 164 of the UN's 193 Member States, it's worth asking how it became a point of contention and ultimately was rejected by more than a dozen countries. The answer? A long lag time between negotiation and adoption, during which overheated claims against it went largely unanswered, as this commentary explores. Full Article
co A Conversation with António Vitorino, the Director General of the International Organization for Migration By www.migrationpolicy.org Published On :: Fri, 22 Feb 2019 12:06:18 -0500 In his first public address on his inaugural official visit to Washington, DC, IOM Director General António Vitorino discusses his vision for IOM; reforms in the UN system; coordination with other organizations in addressing humanitarian protection; and the operational steps IOM is taking to respond to forced migration and displacement. Full Article
co Criminalizing Irregular Migrant Labor: Thailand’s Crackdown in Context By www.migrationpolicy.org Published On :: Tue, 10 Oct 2017 10:05:59 -0400 Thailand has become a key destination for migrant workers, primarily from Myanmar, Cambodia, and Laos. Many lack authorization, however, and as their numbers have grown, so has the government's intent in regulating their movement—sometimes provoking unintended results. This article explores recent patterns in labor migration to Thailand and examines the likely impacts of a 2017 decree criminalizing illegal employment. Full Article
co The Global Compact for Migration: How Does Development Fit In? By www.migrationpolicy.org Published On :: Mon, 27 Nov 2017 12:38:09 -0500 Migration and development are intimately linked, but they have not always shared the international policy stage. As UN Member States kick off negotiations for the Global Compact for Safe, Orderly, and Regular Migration—and with adoption planned for 2018—this brief examines the evolving relationship between these policy areas and considers what a global compact has to offer, if well designed. Full Article
co Moving Beyond “Root Causes:” The Complicated Relationship between Development and Migration By www.migrationpolicy.org Published On :: Tue, 09 Jan 2018 18:12:25 -0500 Development assistance may be a blunt tool for reshaping migration patterns—and indeed one that could increase flows over the short term. Shifting the focus away from increasing individuals’ skills and assets toward investments in the broader economic or governance structures that are a prerequisite for growth and stability may offer more alternatives to emigration in the long run. Full Article
co Welcome to Work? Legal Migration Pathways for Low-Skilled Workers By www.migrationpolicy.org Published On :: Tue, 30 Jan 2018 09:51:37 -0500 Although in many countries immigrants fill labor gaps in fields such as agriculture and construction, few legal migration pathways exist for low-skilled workers. As states meet to negotiate a Global Compact for Safe, Orderly, and Regular Migration, this policy brief takes stock of the channels available for such workers to move legally and take up work abroad, highlighting promising practices and policy gaps. Full Article
co Making the Global Compact on Migration a Reality: Ideas for Enhancing Regular Migration Pathways at All Skill Levels By www.migrationpolicy.org Published On :: Thu, 30 Aug 2018 19:11:37 -0400 As the final phase of preparations for the historic adoption of a Global Compact for Safe, Orderly, and Regular Migration approaches, this webinar explores two central objectives of the compact: enhancing the availability and flexibility of pathways for regular migration, and investing in skills development. Full Article
co Making the Global Compact on Migration a Reality: Ideas for Enhancing Regular Migration Pathways at All Skill Levels By www.migrationpolicy.org Published On :: Wed, 12 Sep 2018 17:30:25 -0400 As the final phase of preparations for the historic adoption of a Global Compact for Safe, Orderly, and Regular Migration approaches, this webinar explores two central objectives of the compact: enhancing the availability and flexibility of pathways for regular migration, and investing in skills development. Full Article
co Understanding the Policy Context for Migrant Return and Reintegration By www.migrationpolicy.org Published On :: Thu, 08 Nov 2018 16:04:53 -0500 In advance of the December 2018 adoption of the Global Compact for Safe, Orderly, and Regular Migration and its commitment to facilitate the return, readmission, and reintegration of migrants, this webinar examines the policies, practices, and contextual factors that make compulsory returns such a difficult issue for international cooperation, and the programs that are being implemented to make reintegration of returnees sustainable. Full Article
co The Road Ahead: Coordination Challenges of Implementing the GCM By www.migrationpolicy.org Published On :: Fri, 30 Nov 2018 10:26:30 -0500 The Member States of the United Nations convened in December to adopt the Global Compact for Safe, Orderly, and Regular Migration (GCM). Ahead of the adoption, this side event in Marrakech (open only to those with GFMD credentials) considered the coordination and mechanisms most needed to achieve the commitments laid out in the GCM. Full Article
co A Once-Smooth Path for the Global Compact on Migration Becomes Rocky By www.migrationpolicy.org Published On :: Tue, 11 Dec 2018 15:48:39 -0500 The world’s first international agreement on migration was approved by 164 countries in December 2018, but not without turbulence. U.S. withdrawal from the nonbinding Global Compact on Safe, Orderly, and Regular Migration, on grounds it could impinge on sovereignty, triggered similar actions by others, particularly in Eastern Europe. Amid ongoing political ripple effects, attention now turns to implementation of the deal's goals. Full Article
co A Tightening Grip Abroad: Authoritarian Regimes Target Their Emigrant and Diaspora Communities By www.migrationpolicy.org Published On :: Wed, 21 Aug 2019 11:46:22 -0400 Authoritarian states have long attempted to restrict citizens’ movement. But what happens when their reach extends beyond their borders? The October 2018 assassination of Saudi journalist Jamal Khashoggi brought into sharp relief the long arm of these regimes in reaching citizens abroad. This phenomenon, “transnational authoritarianism,” further shows that the relationship between migration and authoritarianism is becoming more complex. Full Article
co Democratic Republic of the Congo: A Migration History Marked by Crises and Restrictions By www.migrationpolicy.org Published On :: Tue, 19 Apr 2016 14:11:11 -0400 One of the least developed countries in sub-Saharan Africa, the Democratic Republic of the Congo has experienced significant migration outflows and inflows tied to political and economic crises in recent decades. While most Congolese migrants head to neighboring countries, destinations have diversified, with an uptick in those leaving for opportunities in Europe and beyond. This country profile explores historical and contemporary patterns of migration to and from DR Congo. Full Article
co As Colombia Emerges from Decades of War, Migration Challenges Mount By www.migrationpolicy.org Published On :: Wed, 12 Apr 2017 10:06:18 -0400 Colombia has more internally displaced persons (IDPs) than any other country in the world, the result of a 52-year civil war. Beyond improving the lives of its 7.3 million IDPs, the country faces a number of crucial migration issues as it works to achieve stability in the wake of an historic peace accord signed in late 2016. This country profile examines historical trends and current and future migration challenges in Colombia. Full Article
co Afghanistan: Displacement Challenges in a Country on the Move By www.migrationpolicy.org Published On :: Tue, 14 Nov 2017 15:42:47 -0500 Nearly 6 million Afghans fled after violence erupted in the late 1970s, primarily to Iran and Pakistan. While millions returned after the collapse of the Taliban in 2001, the security situation has since deteriorated and the government struggles to meet the needs of vulnerable populations, particularly the internally displaced. This country profile explores Afghanistan’s complex migration and displacement history as well as ongoing challenges. Full Article
co Australia: A Welcoming Destination for Some By www.migrationpolicy.org Published On :: Mon, 12 Feb 2018 12:34:51 -0500 Immigration has driven economic and social development in Australia for more than two centuries. Even as more than one-fourth of the country’s population is foreign born and Australia ranks third among top refugee resettlement countries worldwide, controversy surrounding its hardline treatment of asylum seekers arriving by boat has cast a shadow on its reputation as a welcoming country, as this article explores. Full Article
co Egypt: Migration and Diaspora Politics in an Emerging Transit Country By www.migrationpolicy.org Published On :: Tue, 07 Aug 2018 17:44:33 -0400 From being a source of labor emigration to the Gulf region to a destination for refugees from Syria, sub-Saharan Africa, and elsewhere, Egypt has long experienced different forms of mobility. This article, which profiles the trends and policies that have shaped Egypt's migration history, focuses on its long-standing use of migration as a soft-power tool to achieve its foreign policy aims and as a safety valve for political discontent. Full Article
co Changing U.S. Policy and Safe-Third Country “Loophole” Drive Irregular Migration to Canada By www.migrationpolicy.org Published On :: Wed, 16 Oct 2019 09:51:08 -0400 Nearly 50,000 asylum seekers have entered Canada irregularly via land crossing from the United States since spring 2017—contributing to a doubling in the overall number of asylum requests seen in 2016. Based on interviews with asylum claimants, this article analyzes their motivations for making the journey and the political implications of rising irregular migration to Canada. Full Article
co Redefining Nepal: Internal Migration in a Post-Conflict, Post-Disaster Society By www.migrationpolicy.org Published On :: Wed, 17 Jun 2015 17:16:02 -0400 Even as Nepal will lean more heavily on its international diaspora to help recover from devastating earthquakes that killed thousands and decimated parts of the country, the disasters have had effects on internal migration. Class and gender dynamics have long driven significant internal flows. This feature article explores migration trends in Nepal, including movement between ecological zones, growing urbanization, and the feminization of an increasingly mobile workforce. Full Article
co Indonesia: A Country Grappling with Migrant Protection at Home and Abroad By www.migrationpolicy.org Published On :: Mon, 17 Sep 2018 11:13:07 -0400 Indonesia, which has a long history as a major origin for migrant labor in the Asia-Pacific and beyond, more recently has reluctantly found itself a transit and destination country, including for asylum seekers. Still, policymakers remain focused on protection of its nationals abroad rather than on assuring the status of Chinese and other foreigners in the country. This country profile explores Indonesia's rich migration history. Full Article
co A Conversation with António Vitorino, the Director General of the International Organization for Migration By www.migrationpolicy.org Published On :: Wed, 06 Mar 2019 16:08:40 -0500 In his first public address during his inaugural formal visit to Washington, DC. International Organization for Migration (IOM) Director General António Vitorino discussed his vision for the agency; reforms in the UN system designed to address migration matters better; the coordination of efforts between IOM, the UN High Commissioner for Refugees, and other international partners in addressing humanitarian protection; and the operational steps IOM is taking to respond to forced migration and displacement in hotspots around the world, including Venezuela, Bangladesh, and Libya. Full Article
co How One Woman Fled Domestic Violence During COVID-19 Pandemic By feeds.socialpsychology.org Published On :: 2020-05-01T06:47:43-04:00 Source: USA Today - Top StoriesWhen the coronavirus initially hit Colorado in early March, many flocked to grocery stores and cleared shelves, preparing to hunker down in their homes. But for Jeara and her four young children, those first days of the pandemic were different: They were settling into a domestic violence shelter after an incident involving her husband days earlier. Full Article
co Signs Your COVID-19 Anxiety Has Become Unhealthy, and What to Do By feeds.socialpsychology.org Published On :: 2020-05-05T02:40:13-04:00 Source: CNN - HealthAs the coronavirus pandemic drags on, experts fear that some of us may begin to lose our ability to cope with the anxiety and stress. Here are five signs that coronavirus anxiety is becoming unhealthy, and tips on how to reduce it. Full Article
co Climate Change and COVID-19: Five Charts That Explain the Impacts By feeds.socialpsychology.org Published On :: 2020-05-05T11:33:35-04:00 Source: BBC News - Top HeadlinesWe're living through the biggest carbon crash ever recorded. No war, no recession, no previous pandemic has had such a dramatic impact on emissions of carbon dioxide over the past century as COVID-19 has in a few short months. What does this unrivaled drop in carbon dioxide mean for climate change? Full Article
co U.N. Chief Says Disabled People Should Be Included in COVID-19 Plans By feeds.socialpsychology.org Published On :: 2020-05-06T09:18:05-04:00 Source: United Press International - Health NewsDisabled people are among the hardest hit by the coronavirus pandemic, United Nations Secretary-General Antonio Guterres said Wednesday, and the inequalities that they already experience are being further intensified by the crisis. To address the problem, Guterres released a report recommending an integrated approach aimed at ensuring people with disabilities are included in response and recovery plans. Full Article
co Color Boost: How Vivid Hues in Your Home Can Lift Your Mood By feeds.socialpsychology.org Published On :: 2020-05-06T09:32:56-04:00 Source: CNN - Top StoriesHow do colors make us feel? This question has guided color specialist Leatrice Eiseman since childhood. As the executive director of the Pantone Color Institute, she leads color trends and forecasts as well as the decision-making behind the company's annual "Color of the Year" (the choice for 2020, Classic Blue, is proving to be an apt calming color for an already anxious year). Full Article
co Navajo Nation Reels Under Weight of Coronavirus and History of Neglect By feeds.socialpsychology.org Published On :: 2020-05-08T13:31:17-04:00 Source: Yahoo News - Top HeadlinesThe Navajo Nation now has the highest per-capita coronavirus infection rate after New York and New Jersey, but it has a fraction of the resources to treat and prevent the pandemic. "This has got to end," said president Jonathan Nez after federal relief funds arrived six weeks after they were promised and a week after the U.S. government missed a congressional deadline for distribution. Full Article
co Reaching a “Fair Deal” on Talent: Emigration, Circulation, and Human Capital in Countries of Origin By www.migrationpolicy.org Published On :: Tue, 02 Feb 2016 10:39:57 -0500 While skilled migration brings widely acknowledged economic benefits for destination countries and migrants, its impact on countries of origin has been the subject of more debate. Despite a growing consensus that origin countries can benefit from emigration and the circulation of skills, enabling this potential to be fully exploited remains a challenge. This report examines initiatives that develop skills and human capital. Full Article
co Achieving Skill Mobility in the ASEAN Economic Community: Challenges, Opportunities, and Policy Implications By www.migrationpolicy.org Published On :: Thu, 11 Feb 2016 10:15:00 -0500 This report by MPI and the Asian Development Bank lays out a realistic roadmap toward freer movement among skilled professionals within the ASEAN Economic Community (AEC), encouraging cooperation among ASEAN Member States in recognizing foreign qualifications and making government investments in training and educations systems that prepare workers in accordance with common standards. Full Article
co The Germany-Turkey Migration Corridor: Refitting Policies for a Transnational Age By www.migrationpolicy.org Published On :: Thu, 18 Feb 2016 10:53:32 -0500 This Transatlantic Council on Migration report describes how the migration of nationals between Germany and Turkey has developed over recent decades; examines the economic, social, and political factors behind this development; and discusses the policy implications and lessons that can be drawn. Full Article
co Firing Up Regional Brain Networks: The Promise of Brain Circulation in the ASEAN Economic Community By www.migrationpolicy.org Published On :: Tue, 14 Feb 2017 09:01:28 -0500 Given diverging demographics, rising educational attainment and wide variation in economic opportunities, countries in the Association of Southeast Asian Nations are poised to see an expansion of both the demand for and supply of skilled migrants willing and able to move. The convergence of these megatrends represents unique opportunities for human-capital development and brain circulation, as this report explores. Full Article
co Children on the Run: An Analysis of First-Hand Accounts from Children Fleeing Central America By www.migrationpolicy.org Published On :: Wed, 05 Mar 2014 12:07:59 -0500 This event with UN High Commissioner for Refugees António Guterres includes a discussion on the state of citizen security in Central America and the resulting humanitarian impact, featuring findings from Children on the Run, a UNHCR report based on interviews with more than 400 unaccompanied children from the region. Full Article
co Regional Enforcement: A Profile of Migrants Deported from the United States and Mexico to the Northern Triangle By www.migrationpolicy.org Published On :: Fri, 28 Aug 2015 12:13:52 -0400 Marking the release of an MPI report, speakers on this webinar present an overview of regional immigration enforcement trends, including U.S. and Mexican apprehensions and deportations of both children and adults, along with a demographic, socioeconomic, and criminal profile of child and adult deportees. Full Article
co Migrants Deported from the United States and Mexico to the Northern Triangle: A Statistical and Socioeconomic Profile By www.migrationpolicy.org Published On :: Mon, 31 Aug 2015 15:46:25 -0400 This report examines the rising numbers of apprehensions and deportations of Central American children and adults by the United States and Mexico, and provides a demographic, socioeconomic, and criminal profile of deportees to El Salvador, Guatemala, and Honduras. The report traces how rising Mexican enforcement is reshaping regional dynamics and perhaps ushering in changes to long-lasting trends in apprehensions. Full Article
co Regional Enforcement: A Profile of Migrants Deported from the United States and Mexico to the Northern Triangle By www.migrationpolicy.org Published On :: Thu, 03 Sep 2015 18:28:05 -0400 This webinar includes an overview of regional immigration enforcement trends, including U.S. and Mexican apprehensions and deportations of Central American migrants, along with a demographic, socioeconomic, and criminal profile of child and adult deportees. Full Article
co La Situación de Cambio Constante entre EE UU y México: Tendencias y Políticas de Migración, Incluyendo Menores No Acompañados By www.migrationpolicy.org Published On :: Wed, 23 Aug 2017 15:25:50 -0400 Una llamada en español que analiza las dinámicas cambiantes y las cuestiones políticas relacionadas con la migración a través de México a los Estados Unidos. Full Article
co La Situación de Cambio Constante entre EE UU y México: Tendencias y Políticas de Migración, Incluyendo Menores No Acompañados By www.migrationpolicy.org Published On :: Fri, 01 Sep 2017 12:31:52 -0400 Durante este seminario, ponentes presentaron hallazgos de un reciente informe que utiliza datos de agencias gubernamentales mexicanas, entrevistas con funcionarios clave y relatos de la sociedad civil para examinar el marco legal para la protección de menores no acompañados y su aplicación, al igual que las brechas entre este marco y su aplicación durante los procesos de detención, interrogación y alojamiento. El presidente de MPI, Andrew Selee, también expuso cómo el cambio en la dinámica política en Estados Unidos puede afectar las cuestiones migratorias con México, así como los efectos en la relación bilateral en medio de tensiones sobre el muro fronterizo, la renegociación del acuerdo del TLCAN y una cifra significativa de repatriaciones de migrantes mexicanos. Full Article
co Vanishing Frontiers: The Forces Driving Mexico and the United States Together By www.migrationpolicy.org Published On :: Thu, 17 May 2018 10:04:04 -0400 Marking the release of MPI President Andrew Selee's book, this discussion explores the emerging trends in migration, economic interdependence, technology innovation, and cultural exchange that are transforming the relationship between the United States and Mexico. Full Article
co Promising Strategies for Reintegration of Migrants Returning to Mexico and Central America By www.migrationpolicy.org Published On :: Mon, 07 Jan 2019 10:55:18 -0500 Authors of a year-long study of reception and reintegration services in Mexico and the Northern Triangle discuss the findings of their fieldwork, including the differing reintegration needs of individual migrant groups, promising reception and reintegration programs, ongoing challenges for origin communities, and policy recommendations to improve reintegration strategies. Full Article
co Economy By www.rssmicro.com Published On :: Sat, 09 May 2020 17:20:27 GMT Economy (date: 5/9/2020 - Rank: 3) Full Article
co COVID By www.rssmicro.com Published On :: Sat, 09 May 2020 17:20:27 GMT COVID (date: 5/9/2020 - Rank: 1) Full Article
co Superior Long-term Survival for Simultaneous Pancreas-Kidney Transplantation as Renal Replacement Therapy: 30-Year Follow-up of a Nationwide Cohort By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE In patients with type 1 diabetes and end-stage renal disease, it is controversial whether a simultaneous pancreas-kidney (SPK) transplantation improves survival compared with kidney transplantation alone. We compared long-term survival in SPK and living- or deceased-donor kidney transplant recipients. RESEARCH DESIGN AND METHODS We included all 2,796 patients with type 1 diabetes in the Netherlands who started renal replacement therapy between 1986 and 2016. We used multivariable Cox regression analyses adjusted for recipient age and sex, dialysis modality and vintage, transplantation era, and donor age to compare all-cause mortality between deceased- or living-donor kidney and SPK transplant recipients. Separately, we analyzed mortality between regions where SPK transplant was the preferred intervention (80% SPK) versus regions where a kidney transplant alone was favored (30% SPK). RESULTS Of 996 transplanted patients, 42%, 16%, and 42% received a deceased- or living-donor kidney or SPK transplant, respectively. Mean (SD) age at transplantation was 50 (11), 48 (11), and 42 (8) years, respectively. Median (95% CI) survival time was 7.3 (6.2; 8.3), 10.5 (7.2; 13.7), and 16.5 (15.1; 17.9) years, respectively. SPK recipients with a functioning pancreas graft at 1 year (91%) had the highest survival (median 17.4 years). Compared with deceased-donor kidney transplant recipients, adjusted hazard ratios (95% CI) for 10- and 20-year all-cause mortality were 0.79 (0.49; 1.29) and 0.98 (0.69; 1.39) for living-donor kidney and 0.67 (0.46; 0.98) and 0.79 (0.60; 1.05) for SPK recipients, respectively. A treatment strategy favoring SPK over kidney transplantation alone showed 10- and 20-year mortality hazard ratios of 0.56 (0.40; 0.78) and 0.69 (0.52; 0.90), respectively. CONCLUSIONS Compared with living- or deceased-donor kidney transplantation, SPK transplant was associated with improved patient survival, especially in recipients with a long-term functioning pancreatic graft, and resulted in an almost twofold lower 10-year mortality rate. Full Article
co Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease--A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Dysglycemia, in this survey defined as impaired glucose tolerance (IGT) or type 2 diabetes, is common in patients with coronary artery disease (CAD) and associated with an unfavorable prognosis. This European survey investigated dysglycemia screening and risk factor management of patients with CAD in relation to standards of European guidelines for cardiovascular subjects. RESEARCH DESIGN AND METHODS The European Society of Cardiology’s European Observational Research Programme (ESC EORP) European Action on Secondary and Primary Prevention by Intervention to Reduce Events (EUROASPIRE) V (2016–2017) included 8,261 CAD patients, aged 18–80 years, from 27 countries. If the glycemic state was unknown, patients underwent an oral glucose tolerance test (OGTT) and measurement of glycated hemoglobin A1c. Lifestyle, risk factors, and pharmacological management were investigated. RESULTS A total of 2,452 patients (29.7%) had known diabetes. OGTT was performed in 4,440 patients with unknown glycemic state, of whom 41.1% were dysglycemic. Without the OGTT, 30% of patients with type 2 diabetes and 70% of those with IGT would not have been detected. The presence of dysglycemia almost doubled from that self-reported to the true proportion after screening. Only approximately one-third of all coronary patients had completely normal glucose metabolism. Of patients with known diabetes, 31% had been advised to attend a diabetes clinic, and only 24% attended. Only 58% of dysglycemic patients were prescribed all cardioprotective drugs, and use of sodium–glucose cotransporter 2 inhibitors (3%) or glucagon-like peptide 1 receptor agonists (1%) was small. CONCLUSIONS Urgent action is required for both screening and management of patients with CAD and dysglycemia, in the expectation of a substantial reduction in risk of further cardiovascular events and in complications of diabetes, as well as longer life expectancy. Full Article
co Glucosamine Use, Inflammation, and Genetic Susceptibility, and Incidence of Type 2 Diabetes: A Prospective Study in UK Biobank By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Glucosamine is a widely used supplement typically taken for osteoarthritis and joint pain. Emerging evidence suggests potential links of glucosamine with glucose metabolism, inflammation, and cardiometabolic risk. We prospectively analyzed the association of habitual glucosamine use with risk of type 2 diabetes (T2D) and assessed whether genetic susceptibility and inflammation status might modify the association. RESEARCH DESIGN AND METHODS This study analyzed 404,508 participants from the UK Biobank who were free of diabetes, cancer, or cardiovascular disease at baseline and completed the questionnaire on supplement use. Cox proportional hazards models were used to evaluate the association between habitual use of glucosamine and risk of incident T2D. RESULTS During a median of 8.1 years of follow-up, 7,228 incident cases of T2D were documented. Glucosamine use was associated with a significantly lower risk of T2D (hazard ratio 0.83, 95% CI 0.78–0.89) after adjustment for age, sex, BMI, race, center, Townsend deprivation index, lifestyle factors, history of disease, and other supplement use. This inverse association was more pronounced in participants with a higher blood level of baseline C-reactive protein than in those with a lower level of this inflammation marker (P-interaction = 0.02). A genetic risk score for T2D did not modify this association (P-interaction = 0.99). CONCLUSIONS Our findings indicate that glucosamine use is associated with a lower risk of incident T2D. Full Article
co Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Reparixin is an inhibitor of CXCR1/2 chemokine receptor shown to be an effective anti-inflammatory adjuvant in a pilot clinical trial in allotransplant recipients. RESEARCH DESIGN AND METHODS A phase 3, multicenter, randomized, double-blind, parallel-assignment study (NCT01817959) was conducted in recipients of islet allotransplants randomized (2:1) to reparixin or placebo in addition to immunosuppression. Primary outcome was the area under the curve (AUC) for C-peptide during the mixed-meal tolerance test at day 75 ± 5 after the first and day 365 ± 14 after the last transplant. Secondary end points included insulin independence and standard measures of glycemic control. RESULTS The intention-to-treat analysis did not show a significant difference in C-peptide AUC at both day 75 (27 on reparixin vs. 18 on placebo, P = 0.99) and day 365 (24 on reparixin vs. 15 on placebo, P = 0.71). There was no statistically significant difference between treatment groups at any time point for any secondary variable. Analysis of patient subsets showed a trend for a higher percentage of subjects retaining insulin independence for 1 year after a single islet infusion in patients receiving reparixin as compared with patients receiving placebo (26.7% vs. 0%, P = 0.09) when antithymocyte globulin was used as induction immunosuppression. CONCLUSIONS In this first double-blind randomized trial, islet transplantation data obtained with reparixin do not support a role of CXCR1/2 inhibition in preventing islet inflammation-mediated damage. Full Article
co The Future of Enrichment: Math Contests or Math Circles? By blogs.ams.org Published On :: Mon, 13 Jan 2020 07:36:00 +0000 by Doug O’Roark Executive Director, Math Circles of Chicago The New York Times recently published an article entitled “The Right Answer? 8,186,699,633,530,061 (An Abacus Makes It Look Almost Easy)”. Its lead photograph features over 100 children seated at desks, facing … Continue reading → Full Article K-12 Education Mathematics Education Research Outreach Student Experiences extra-curricular math circles math contests math festivals
co Help! I need to teach my course online and I’ve never done this before By blogs.ams.org Published On :: Mon, 16 Mar 2020 16:05:52 +0000 By: Yvonne Lai, University of Nebraska-Lincoln Ray Levy, Mathematical Association of America This is cross-posted in MathValues and Abbe Herzig has written a companion post. Additional resources and future meetings are also available here: https://tinyurl.com/OnlineTalkshop. In times of crisis we … Continue reading → Full Article Faculty Experiences Online Education
co Online learning in the time of Coronavirus: Tips for students and the instructors who support them By blogs.ams.org Published On :: Mon, 30 Mar 2020 10:00:26 +0000 Abbe Herzig, AMS Director of Education In the midst of the upheaval due to the Coronavirus, students and faculty are transitioning to new virtual classrooms. Many of us haven’t chosen to learn or teach, but here we are, making the … Continue reading → Full Article Graduate Education Mathematics Education Research Online Education Student Experiences education Mathematics Education online learning
co Dallas Cowboys sign former first-round pick Cameron Erving By www.upi.com Published On :: Wed, 06 May 2020 19:14:49 -0400 The Dallas Cowboys agreed to terms with free-agent offensive lineman Cameron Erving, the team announced Wednesday. Full Article
co NFL lays out protocols for reopening of team facilities By www.upi.com Published On :: Wed, 06 May 2020 23:33:40 -0400 The NFL outlined protocols Wednesday for the gradual reopening of team facilities amid the coronavirus pandemic. Full Article