at Method and apparatus for processing audio frames to transition between different codecs By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method (700, 800) and apparatus (100, 200) processes audio frames to transition between different codecs. The method can include producing (720), using a first coding method, a first frame of coded output audio samples by coding a first audio frame in a sequence of frames. The method can include forming (730) an overlap-add portion of the first frame using the first coding method. The method can include generating (740) a combination first frame of coded audio samples based on combining the first frame of coded output audio samples with the overlap-add portion of the first frame. The method can include initializing (760) a state of a second coding method based on the combination first frame of coded audio samples. The method can include constructing (770) an output signal based on the initialized state of the second coding method. Full Article
at Encoder, decoder and methods for encoding and decoding data segments representing a time-domain data stream By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An apparatus for decoding data segments representing a time-domain data stream, a data segment being encoded in the time domain or in the frequency domain, a data segment being encoded in the frequency domain having successive blocks of data representing successive and overlapping blocks of time-domain data samples. The apparatus includes a time-domain decoder for decoding a data segment being encoded in the time domain and a processor for processing the data segment being encoded in the frequency domain and output data of the time-domain decoder to obtain overlapping time-domain data blocks. The apparatus further includes an overlap/add-combiner for combining the overlapping time-domain data blocks to obtain a decoded data segment of the time-domain data stream. Full Article
at System and methods for matching an utterance to a template hierarchy By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system and methods for matching at least one word of an utterance against a set of template hierarchies to select the best matching template or set of templates corresponding to the utterance. Certain embodiments of the system and methods determines at least one exact, inexact, and partial match between the at least one word of the utterance and at least one term within the template hierarchy to select and populate a template or set of templates corresponding to the utterance. The populated template or set of templates may then be used to generate a narrative template or a report template. Full Article
at System, method and program product for providing automatic speech recognition (ASR) in a shared resource environment By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A speech recognition system, method of recognizing speech and a computer program product therefor. A client device identified with a context for an associated user selectively streams audio to a provider computer, e.g., a cloud computer. Speech recognition receives streaming audio, maps utterances to specific textual candidates and determines a likelihood of a correct match for each mapped textual candidate. A context model selectively winnows candidate to resolve recognition ambiguity according to context whenever multiple textual candidates are recognized as potential matches for the same mapped utterance. Matches are used to update the context model, which may be used for multiple users in the same context. Full Article
at Language model creation device By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT This device 301 stores a first content-specific language model representing a probability that a specific word appears in a word sequence representing a first content, and a second content-specific language model representing a probability that the specific word appears in a word sequence representing a second content. Based on a first probability parameter representing a probability that a content represented by a target word sequence included in a speech recognition hypothesis generated by a speech recognition process of recognizing a word sequence corresponding to a speech, a second probability parameter representing a probability that the content represented by the target word sequence is a second content, the first content-specific language model and the second content-specific language model, the device creates a language model representing a probability that the specific word appears in a word sequence corresponding to a part corresponding to the target word sequence of the speech. Full Article
at Low power activation of a voice activated device By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT In a mobile device, a bone conduction or vibration sensor is used to detect the user's speech and the resulting output is used as the source for a low power Voice Trigger (VT) circuit that can activate the Automatic Speech Recognition (ASR) of the host device. This invention is applicable to mobile devices such as wearable computers with head mounted displays, mobile phones and wireless headsets and headphones which use speech recognition for the entering of input commands and control. The speech sensor can be a bone conduction microphone used to detect sound vibrations in the skull, or a vibration sensor, used to detect sound pressure vibrations from the user's speech. This VT circuit can be independent of any audio components of the host device and can therefore be designed to consume ultra-low power. Hence, this VT circuit can be active when the host device is in a sleeping state and can be used to wake the host device on detection of speech from the user. This VT circuit will be resistant to outside noise and react solely to the user's voice. Full Article
at Messaging response system providing translation and conversion written language into different spoken language By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A messaging response system is disclosed wherein a service providing system provides services to users via messaging communications. In accordance with an exemplary embodiment of the present invention, multiple respondents servicing users through messaging communications may appear to simultaneously use a common “screen name” identifier. Full Article
at Systems, methods, and apparatus for gain factor attenuation By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method of signal processing according to one embodiment includes calculating an envelope of a first signal that is based on a low-frequency portion of a speech signal, calculating an envelope of a second signal that is based on a high-frequency portion of the speech signal, and calculating a plurality of gain factor values according to a time-varying relation between the envelopes of the first and second signal. The method includes attenuating, based on a variation over time of a relation between the envelopes of the first and second signals, at least one of the plurality of gain factor values. In one example, the variation over time of a relation between the envelopes is indicated by at least one distance among the plurality of gain factor values. Full Article
at Audio signal decoder, time warp contour data provider, method and computer program By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An audio signal decoder has a time warp contour calculator, a time warp contour data rescaler and a warp decoder. The time warp contour calculator is configured to generate time warp contour data repeatedly restarting from a predetermined time warp contour start value, based on time warp contour evolution information describing a temporal evolution of the time warp contour. The time warp contour data rescaler is configured to rescale at least a portion of the time warp contour data such that a discontinuity at a restart is avoided, reduced or eliminated in a rescaled version of the time warp contour. The warp decoder is configured to provide the decoded audio signal representation, based on an encoded audio signal representation and using the rescaled version of the time warp contour. Full Article
at Apparatus and method for encoding and decoding an audio signal using an aligned look-ahead portion By www.freepatentsonline.com Published On :: Tue, 02 Jun 2015 08:00:00 EDT An apparatus for encoding an audio signal having a stream of audio samples has: a windower for applying a prediction coding analysis window to the stream of audio samples to obtain windowed data for a prediction analysis and for applying a transform coding analysis window to the stream of audio samples to obtain windowed data for a transform analysis, wherein the transform coding analysis window is associated with audio samples within a current frame of audio samples and with audio samples of a predefined portion of a future frame of audio samples being a transform-coding look-ahead portion, wherein the prediction coding analysis window is associated with at least the portion of the audio samples of the current frame and with audio samples of a predefined portion of the future frame being a prediction coding look-ahead portion, wherein the transform coding look-ahead portion and the prediction coding look-ahead portion are identically to each other or are different from each other by less than 20%; and an encoding processor for generating prediction coded data or for generating transform coded data. Full Article
at Method, system, and computer readable medium for creating clusters of text in an electronic document By www.freepatentsonline.com Published On :: Tue, 21 Jul 2015 08:00:00 EDT Disclosed herein are systems and methods for navigating electronic texts. According to an aspect, a method may include determining text subgroups within an electronic text. The method may also include selecting a text seed within one of the text subgroups. Further, the method may include determining a similarity relationship between the text seed and one or more adjacent text subgroups that do not include the selected text seed. The method may also include associating the text seed with the one or more adjacent text subgroups based on the similarity relationship to create a text cluster. Full Article
at Time warp contour calculator, audio signal encoder, encoded audio signal representation, methods and computer program By www.freepatentsonline.com Published On :: Tue, 29 Mar 2016 08:00:00 EDT A time warp contour calculator for use in an audio signal decoder receives an encoded warp ratio information, derives a sequence of warp ratio values from the encoded warp ratio information, and obtains warp contour node values starting from a time warp contour start value. Ratios between the time warp contour node values and the time warp contour starting value are determined by the warp ratio values. The time warp contour calculator computes a time warp contour node value of a given time warp contour node, on the basis of a product-formation having a ratio between the time warp contour node values of the intermediate time warp contour node and the time warp contour starting value and a ratio between the time warp contour node values of the given time warp contour node and of the intermediate time warp contour node as factors. Full Article
at Error concealment method and apparatus for audio signal and decoding method and apparatus for audio signal using the same By www.freepatentsonline.com Published On :: Tue, 21 Jun 2016 08:00:00 EDT An error concealment method and apparatus for an audio signal and a decoding method and apparatus for an audio signal using the error concealment method and apparatus. The error concealment method includes selecting one of an error concealment in a frequency domain and an error concealment in a time domain as an error concealment scheme for a current frame based on a predetermined criteria when an error occurs in the current frame, selecting one of a repetition scheme and an interpolation scheme in the frequency domain as the error concealment scheme for the current frame based on a predetermined criteria when the error concealment in the frequency domain is selected, and concealing the error of the current frame using the selected scheme. Full Article
at Methods and systems for creating a shaped playlist By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Methods and systems are described for generating media playlists, or selecting a media asset, according to a “shape” selected by a user. Specifically, a user may “shape” the playlist by designating specific sub-categories of media assets that should be presented at selected times in the playlist. The media application then interpolates the sub-categories for a media asset between the selected times such that adjacent media assets have smooth categorical transitions (e.g., feature incremental changes in the range of sub-categories). Full Article
at Method for configuring displets for an interactive platform for analyzing a computer network performance By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A method for configuring an interactive platform for monitoring the performance and the quality of a computer network, the monitoring data being suitable to be displayed on a dynamic page of type webpage in a form of graphic components called “displets”; including providing, on the interactive platform a configuration interface in which are defined, for at least one given user, filtering criteria for displaying displets, the criteria being defined in the form of parameters for configuring the rights of the at least one user. Full Article
at Information processing apparatus, information processing system, information processing apparatus control method, and storage medium By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An information processing apparatus according to this invention, being capable of communicating with a Web server via a network, receives from the Web server a response to a processing request issued to a Web application of the Web server. The information processing apparatus changes, when screen control information described in a header of the response contains information which designates priority of a screen display by a Web browser of the information processing apparatus, priority of the screen display by the Web browser to the designated priority. When an event to display a screen other than a screen by the Web browser occurs while the Web browser presents a screen display corresponding to the response, the information processing apparatus inhibits an interrupt display by the event in order for the designated priority. Full Article
at Switch control in report generation By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT In one embodiment, a view in a graphical user interface includes a selection area that includes identifiers associated with a plurality of attributes, each of the attributes having a plurality of possible values. The area further includes one or more graphical tools to define filter criteria based at least in part on selected ones of the plurality of possible values of one or more of the attributes. The area further includes one or more switch controls each being associated with a respective one of the one or more of the attributes and indicating presentation criteria including: whether selected ones of the possible values of the respective attribute are to be shown in a report, and a dimension of the report in which to space the selected ones of the possible values from one another if the selected ones of the possible values are to be shown in the report. Full Article
at System and method for simultaneous display of multiple information sources By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A computerized method of presenting information from a variety of sources on a display device. Specifically the present invention describes a graphical user interface for organizing the simultaneous display of information from a multitude of information sources. In particular, the present invention comprises a graphical user interface which organizes content from a variety of information sources into a grid of tiles, each of which can refresh its content independently of the others. The grid functionality manages the refresh rates of the multiple information sources. The present invention is intended to operate in a platform independent manner. Full Article
at Information processing apparatus for displaying screen information acquired from an outside device in a designated color By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT An information processing apparatus configured to display a user interface on a display unit according to screen information acquired from an outside device changes the screen information according to a display attribute set by a user, and if setting of a display attribute of an object included in the screen information is unchangeable, color conversion processing of a specified object included in the screen information is performed and the screen information obtained by executing conversion processing according to the display attribute set by the user with respect to the screen information including the object which has undergone the color conversion processing is displayed. Full Article
at Alert event notification By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Alert event notifications may be provided by: displaying a first user interface layer including at least one user interface element configured to provide an alert event notification; displaying a second user interface layer such that at least a portion of the second user interface layer overlays the at least one user interface element configured to provide an alert event notification; detecting an alert event; and at least partially displaying the at least one user interface element configured to provide an alert event notification in an area where the at least a portion of the second user interface layer overlays the at least one user interface element configured to provide an alert event notification. Full Article
at Methods and apparatus to create process control graphics based on process control information By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Methods and apparatus to automatically link process control graphics to process control algorithm information are described. An example method involves displaying a first process control image including process control algorithm information and displaying adjacent to the first process control image a second process control image to include process control graphics. The method automatically links at least some of the process control algorithm information to a graphic in the second process control image in response to user inputs associated with the first and second process control images. Full Article
at Multi-lane time-synched visualizations of machine data events By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A visualization can include a set of swim lanes, each swim lane representing information about an event type. An event type can be specified, e.g., as those events having certain keywords and/or having specified value(s) for specified field(s). The swim lane can plot when (within a time range) events of the associated event type occurred. Specifically, each such event can be assigned to a bucket having a bucket time matching the event time. A swim lane can extend along a timeline axis in the visualization, and the buckets can be positioned at a point along the axis that represents the bucket time. Thus, the visualization may indicate whether events were clustered at a point in time. Because the visualization can include a plurality of swim lanes, the visualization can further indicate how timing of events of a first type compare to timing of events of a second type. Full Article
at System and method for managing and displaying securities market information By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A message screen display comprises a static non-scrollable display area for display of at least part of a first message, the first message having an associated first message time. The message screen display further comprises a scrollable display area for display of at least part of a second message, the second message having an associated second message time. The message screen display further comprises a feature applied to at least part of the first message that varies based on time as referenced to the associated first message time. Full Article
at Post selection mouse pointer location By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A technique is provided for post selection location of a mouse pointer icon in a display screen of a computing device. A software tool receives input of the post selection location for the mouse pointer icon. The post selection location defines a default location to move the mouse pointer icon in response to a window action taken on a window displayed in the display screen. In response to the window action in which the mouse pointer icon is initially displayed at a selection location corresponding to the window action, the mouse pointer icon is moved to the post selection location such that the mouse pointer icon is displayed at the post selection location in the display screen. Full Article
at Vehicular manipulation apparatus By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A remote manipulation apparatus includes a main body and a manipulating handle manipulated by a user to move to cover all the orientations from a manipulation basis position defined on a basis of the main body. Movement of the manipulating handle relative to the manipulation basis position corresponds to movement of a pointer image relative to a screen basis position on a screen of a display apparatus. An auxiliary navigational display window includes a specified button image assigned with pointer-pulling information. When the auxiliary navigational display window appears on the screen, the manipulating handle is automatically driven to a position that corresponds to a position of the specified button image on the screen so that the pointer image is moved onto the specified button image that is assigned with the pointer-pulling information. Full Article
at User interfaces for displaying relationships between cells in a grid By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT User interfaces for displaying relationships between cells in a grid. In one example embodiment, a user interface includes a grid including rows and columns and a plurality of cells each having a specific position in the grid. A first one of the cells is related to a second one of the cells. The grid is configured to display, upon selection of the first cell or second cell, a visual representation of the relationship between the first cell and the second cell. Full Article
at Representation of overlapping visual entities By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Various embodiments present a combined visual entity that represents overlapping visual entities. The combined visual entity can include a primary visualization that represents one of the overlapping visual entities and annotations that represent others of the overlapping visual entities. For example, a map view can include multiple geographical entities that overlap. A primary visualization can be rendered that represents one of the multiple geographical entities. The primary visualization can be visually annotated (e.g., with symbols, letters, or other visual indicators) to indicate others of the multiple geographical entities. In some embodiments, a zoom operation can cause visual entities to be added and/or removed from the combined visual entity. Full Article
at Visualization techniques for imprecise statement completion By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT When a user enters text into an application, the application can utilize an auto-complete feature to provide the user with estimations as to a complete term a user is attempting to enter into the application. Visualization can be provided along with an estimation to disclose the likelihood the estimation is what the user intends to enter. Furthermore, a rationale can be provided to the user for the reason an estimation was provided to the user. Full Article
at Data processing apparatus, data processing method of data processing apparatus, and computer-readable memory medium storing program therein By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT To freely establish a peripheral equipment selection operating environment of excellent operability which can remarkably reduce an operation burden which is applied until construction information of selectable peripheral equipment can be confirmed and can easily confirm the construction information of the selectable peripheral equipment by everyone by a simple operating instruction, a CPU obtains construction information of a printer that is being selected and default setting on the basis of a selection instructing state relative to a selectable printer candidate on a network and allows them to be caption-displayed at a position near the position indicated by a cursor on a printer selection picture plane displayed on a CRT. Full Article
at Apparatus and method for user input for controlling displayed information By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT In accordance with an example embodiment of the present invention, a method for proximity based input is provided, comprising: detecting presence of an object in close proximity to an input surface, detecting a displayed virtual layer currently associated with the object on the basis of distance of the object to the input surface, detecting a hovering input by the object, and causing a display operation to move at least a portion of the associated virtual layer in accordance with the detected hovering input. Full Article
at Detecting automated identities in computer user communities By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A computer-implemented method of detecting automated identities, including. The method includes, using one or more computing devices, providing for display to a user a first representation of a first profile for a first identity and a second representation of a second profile for a second identity, providing for display to the user a choice indication mechanism for indicating a judgment about the first representation of the first profile for the first identity and the second representation of the second profile for the second identity, receiving an indication of the judgment from the user about the first representation of the first profile for the first identity and the second representation of the second profile for the second identity, and determining whether at least one of the first identity, the second identity, or the user is more or less likely to be automated, based at least in part on the received indication. Full Article
at Device, method, and graphical user interface for managing concurrently open software applications By www.freepatentsonline.com Published On :: Tue, 16 Jun 2015 08:00:00 EDT A method includes displaying a first application view. A first input is detected, and an application view selection mode is entered for selecting one of concurrently open applications for display in a corresponding application view. An initial group of open application icons in a first predefined area and at least a portion of the first application view adjacent to the first predefined area are concurrently displayed. The initial group of open application icons corresponds to at least some of the concurrently open applications. A gesture is detected on a respective open application icon in the first predefined area, and a respective application view for a corresponding application is displayed without concurrently displaying an application view for any other application in the concurrently open applications. The open application icons in the first predefined area cease to be displayed, and the application view selection mode is exited. Full Article
at Handheld electronic device and method for performing spell checking during text entry and for providing a spell-check learning feature By www.freepatentsonline.com Published On :: Tue, 16 Jun 2015 08:00:00 EDT A handheld electronic device includes a reduced QWERTY keyboard and is enabled with a disambiguation routine that is operable to disambiguate text input. In addition to identifying and outputting representations of language objects that are stored in the memory and that correspond with a text input, the device is able to perform a spell check routine during input of a text entry and to learn and automatically correct mistakes typically made by the particular user. Full Article
at Method and apparatus for aliased item selection from a list of items By www.freepatentsonline.com Published On :: Tue, 16 Jun 2015 08:00:00 EDT The present invention introduces an aliased selection system with audible cues to allow a user of a handheld computer system locate a desired item from a list of item. The aliased selection system allows a user to spell out a desired item by activating an input that specifics a subset that containing a next letter. In one embodiment, two different subsets are used: A to M and N to Z. When the user has entered information on enough letters such that the number of possibilities fits entirely on a display screen then a first audible cue is given. The user may enter additional information on until a single list item is uniquely identified. Once a single item is uniquely identified, the system emits a second audible cue that informs the user that a single item has been specified. The aliased selection system allows a user to select a desired item from a list with a single hand and without looking at the display screen. However, the user may shorten the selection process by looking at the display screen. Full Article
at Translating user motion into multiple object responses By www.freepatentsonline.com Published On :: Tue, 07 Jul 2015 08:00:00 EDT A system for translating user motion into multiple object responses of an on-screen object based on user interaction of an application executing on a computing device is provided. User motion data is received from a capture device from one or more users. The user motion data corresponds to user interaction with an on-screen object presented in the application. The on-screen object corresponds to an object other than an on-screen representation of a user that is displayed by the computing device. The user motion data is automatically translated into multiple object responses of the on-screen object. The multiple object responses of the on-screen object are simultaneously displayed to the users. Full Article
at Controlling the rendering of supplemental content related to electronic books By www.freepatentsonline.com Published On :: Tue, 25 Aug 2015 08:00:00 EDT Architectures and techniques are provided to control the rendering of supplemental content associated with electronic books. For example, electronic books may be associated with content that is in addition to the content originally provided to an individual acquiring the electronic book, such as annotations, social networking site information, media outlet information, and the like. Individuals may control the supplemental electronic book content that is rendered via their client devices via actuation of a physical input device or a representation of an input device shown via a touch sensitive display. The amount of supplemental content that is rendered may correspond to information associated with a specified number of categories of supplemental electronic book content based on a supplemental content rendering level. In other implementations, the amount of supplemental electronic book content that is rendered may correspond to an amount of supplemental content to be rendered for each category of supplemental content. Full Article
at Analysis of images located within three-dimensional environments By www.freepatentsonline.com Published On :: Tue, 01 Sep 2015 08:00:00 EDT Images are analyzed within a 3D environment that is generated based on spatial relationships of the images and that allows users to experience the images in the 3D environment. Image analysis may include ranking images based on user viewing information, such as the number of users who have viewed an image and how long an image was viewed. Image analysis may further include analyzing the spatial density of images within a 3D environment to determine points of user interest. Full Article
at Method and apparatus for annotating an electronic document By www.freepatentsonline.com Published On :: Tue, 17 Nov 2015 08:00:00 EST A method and apparatus to mark-up an electronic document (i.e., a second electronic document) that is superimposed on a first electronic document keeping the first electronic document unchanged. The second electronic document is optionally viewed concurrently with the first electronic document. The second electronic document is capable of being viewed or modified using different application programs so long as the different application programs process the format used by the second electronic document. The second electronic document is saved as a separate document independent of the first electronic document. Full Article
at Soft-sending chat messages By www.freepatentsonline.com Published On :: Tue, 26 Jan 2016 08:00:00 EST Techniques are disclosed for supplying users in an online environment with a safe and effective chat facility. The chat facility is “safe” in the sense that the ability of users to compose inappropriate messages is greatly restricted, while “effective” in the sense that users are still allowed a broad range of expressivity in composing and exchanging chat messages. Full Article
at Addition-fragmentation agents By www.freepatentsonline.com Published On :: Tue, 17 Mar 2015 08:00:00 EDT Addition-fragmentation agents of the formula are disclosed having the following functional groups: 1) a labile addition-fragmentation group that can cleave and reform to relieve strain, 2) a free-radically polymerizable group, and 3) a surface-modifying functional group that associates with the surface of a substrate. Full Article
at Catalytic system for CO2/epoxide copolymerization By www.freepatentsonline.com Published On :: Tue, 17 Mar 2015 08:00:00 EDT The present invention related to a method of manufacturing a polycarbonate including the process of copolymerizing epoxide compound and CO2 using cobalt(III) or chromium(III), where the ligands contains at least 3 ammonium cations, central metal has formal −1 charge, and conjugated anions of the two cationic ammonium groups are acid-base homoconjugation, as catalyst. According to the present invention, the initial induction time can be reduced when the said polycarbonate is manufactured and it is possible to improve the activity of the catalyst and the molecular weight of the obtained polymer. Full Article
at Isocyanate and isothiocyanate compounds for cancer treatment By www.freepatentsonline.com Published On :: Tue, 24 Mar 2015 08:00:00 EDT The present invention relates to novel isocyanate and isothiocyanate compounds, to pharmaceutical compositions comprising them, and to the use thereof in the treatment of cancer diseases in humans and animals. The novel isocyanate and isothiocyanate compounds are distinguished, as compared with the known isocyanate and isothiocyanate compounds, by improved therapeutical breadth, i.e. fewer side effects while having high anti-tumor activity. Full Article
at Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method By www.freepatentsonline.com Published On :: Tue, 24 Mar 2015 08:00:00 EDT Provided is an efficient technology for synthesizing diamino acids (diamino acid derivatives). Disclosed is a manufacturing method for diamino acid derivatives wherein the fluorenyl groups of the diamino acid derivative starting materials represented by General Formula [II] or [IV] are removed. Full Article
at Point of use generation of amyl nitrite By www.freepatentsonline.com Published On :: Tue, 24 Mar 2015 08:00:00 EDT The present disclosure relates to devices and methods for the preparation of amyl nitrite formulations at a point of use location from relatively shelf-stable reagents employing acidic cationic exchange resins. Full Article
at Aminohydroxylation of alkenes By www.freepatentsonline.com Published On :: Tue, 24 Mar 2015 08:00:00 EDT The invention relates to a process for the aminohydroxylation of alkenes using N-oxycarbamate reagents, e.g. N-acyloxycarbamate, N-alkyloxycarbonyloxycarbamate and N-aralkoxycarbonyloxycarbamate reagents. The invention particularly relates to an intermolecular aminohydroxylation reaction that can be carried out in the absence of added base. The invention also relates to novel N-oxycarbamate reagents that are stable crystalline materials. The process of the invention is useful in the synthesis of compounds having a vicinal amino alcohol moiety, such as biologically active compounds. Full Article
at Carbonate prodrugs and methods of using the same By www.freepatentsonline.com Published On :: Tue, 31 Mar 2015 08:00:00 EDT The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages. Full Article
at Isomerized alpha olefin sulfonate and method of making the same By www.freepatentsonline.com Published On :: Tue, 31 Mar 2015 08:00:00 EDT The present invention is directed to an isomerized alpha olefin sulfonate and a method of making the same wherein the isomerized alpha olefin sulfonate is derived from sulfonating an isomerized alpha olefin with sulfur trioxide in the presence of air thereby producing an isomerized alpha olefin sulfonic acid, wherein the isomerized alpha olefin is derived from the isomerization of C12-C20 normal alpha olefins; and neutralizing the isomerized alpha olefin sulfonic acid with a source of an alkali metal or ammonium or substituted ammonium ion. Full Article
at Precursors of glutamate derivatives By www.freepatentsonline.com Published On :: Tue, 07 Apr 2015 08:00:00 EDT This invention relates to novel precursors suitable for 18F radiolabeling of glutamate derivatives, methods for preparing such compounds and its intermediates, compositions comprising such compounds, kits comprising such compounds or compositions and methods for 18F radiolabeling of glutamate derivatives wherein the obtained 18F radiolabeled glutamate derivatives are suitable for diagnostic imaging by Positron Emission Tomography (PET) of proliferative diseases e.g. tumor in mammals. Full Article
at Process for the preparation of fluoroalkyl (fluoro)alkyl carbonates and carbamates By www.freepatentsonline.com Published On :: Tue, 07 Apr 2015 08:00:00 EDT Fluoroalkyl alkyl carbonates and fluorosubstituted carbamates which are suitable as additives or solvents in lithium ion batteries are prepared from fluoroalkyl fluoroformates and the respective alcohol or amine. Methanol is the preferred alcohol, dimethylamine and diethylamine are preferred amines. Fluoromethyl methyl carbonate is the preferred compound to be produced. Fluoroalkyl fluoroformates can be prepared from aldehydes and carbonyl fluoride. Full Article
at Process for the preparation of 2-cyanophenylboronic acid and esters thereof By www.freepatentsonline.com Published On :: Tue, 07 Apr 2015 08:00:00 EDT The present invention relates to a process for the synthesis of 2-cyanophenylboronic acid and the esters and salts thereof of formula (II), which are intermediates of the synthesis of active pharmaceutical ingredients such as Perampanel or E2040. formula (II): (II). Full Article